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statistics-enrichment-analysis/IllustratePathwayEnrichmentMethods.R
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@ -39,6 +39,11 @@ diff.res <- dds.bc %>%
diff.res %>%
plotMA(.)
##output the results
diff.res %>%
as.data.frame() %>%
rownames_to_column('Gene') %>%
write.csv(., "bladder_cancer_diff_exp_results.csv", row.names = FALSE)
##load the pathway gene set data-bases
database_lists <- load("databases.RData")#has wp, pfocr, go

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---
title: "Statistics of Enrichment Analyses"
author: "Reuben Thomas"
date: "8/12/2021"
output: html_document
---
```{r setup, include=FALSE}
knitr::opts_chunk$set(echo = TRUE)
```
Let us load the libraries requires for the various analyses described in this document
```{r}
##libraries for "tidy" manipulation of data
suppressMessages(library(tidyverse))
##libraries for "tidy" manipulation of data
suppressMessages(library(magrittr))
##library used for normalizing gene expression data and then perform statistical association of gene expression with tumor vs normal comparison of bladder cancer samples
suppressMessages(library(DESeq2))
##library used for generating a Volcano Plot
suppressMessages(library(EnhancedVolcano))
##library to illustrate the use of Over Representation Analyses (ORA) and Gene Set Enrichment Analyses (GSEA) with gene permutation
suppressMessages(library(clusterProfiler))
##library to illustrate the use of Simulataneous Enrichment Analyses (SEA)
suppressMessages(library(rSEA))
##library to illustrate the use of Significance Analysis of Function and Expression (SAFE), Pathway Analysis with Down-weighting of Overlapping Genes (PADOG) and Gene Set Enrichment Analyses (GSEA) with sample permutation
suppressMessages(library(GSEABenchmarkeR))
```
# Scientific Question
*What are the biological pathways/gene sets differerntially regulated between the tumor and normal tissues in bladder cancer patients?*
# Data
The gene expression we will work with are assayed using RNA-seq in the tumor and normal tissues drawn from 19 subjects with bladder cancer. These data are derived from [The Cancer Genome Atlas](https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga) (TCGA).
# Methods
The methods we will use to answer the scientific question are described below:
1. Load the gene expression data and understand the study design
2. Perform differential expression analyses
3. Run six different enrichment analyses methods.
**Note:** In normal practice we may run only one or at most two methods to answer our question. However, our purpose here is to illustrate the use of different methods, higlight and interpret their results in the context of the associated assumptions of each method. The choice of the methods we use will depend on ...
a. ... the nature of our hypothesis, i.e., are we interested in a very specific biochemical pathway? or
b. ... are we agnostic of the nature of the biochemical pathways we discover to be asssociated with what we are studying?,
c. ... if we want to interpret the resulting p-values as measures of reproducibility of our enriched pathways by other research groups using data derived from new bladder cancer patient samples?
d. ... whether the assay we are using is a genome-wide assay or a very targeted assay focusing on a specific group of genes or proteins
# Analyses
## Load the data and understand the experimental data
The gene expression data will be loaded as a [SummarizedExperiment](https://bioconductor.org/packages/release/bioc/html/SummarizedExperiment.html) object in an [RDS](https://www.rdocumentation.org/packages/base/versions/3.6.2/topics/readRDS) file.
```{r}
tcga <- readRDS("bladder_cancer_tcga_summarized_experiment.rds")
##short summary of tcga. Note the 12,264 rownames represent the gene names as Entrez IDs
tcga
print("Short summary of the RNA-seq samples")
##quick summary of 38 samples. Note the variable GROUP refers to tumor vs normal assignment while the variable BLOCK refers to the patient. From each of the 19 patients, tumor and normal tissue are derived and assayed for gene expression
colData(tcga)
##turn the GROUP and BLOCK variables to categorical variables
tcga$GROUP <- as.factor(tcga$GROUP)
tcga$BLOCK <- as.factor(tcga$BLOCK)
print("Look at the read counts of 4 genes for a 5 samples")
(assays(tcga))$exprs[1:4,1:5]
```
## Differential expression analyses
```{r message=FALSE}
##create a DESeq data object
dds.bc <- DESeqDataSet(tcga, design = ~ GROUP + BLOCK)
##estimate normalization/size-factors and dispersions
dds.bc %<>% DESeq(.)
##variance stabilizing transformation to view the normalize data
vsd.bc <- dds.bc %>%
vst(., blind=TRUE)
##generate the PCA plot using the normalized data. Note the clustering of the samples by the tumor versus normal comparisons
vsd.bc %>%
plotPCA(., intgroup=c("GROUP"))
##differential expression association for tumor versus normal differences controlling for patient specific differences
diff.res <- dds.bc %>%
results(., contrast = c("GROUP", "1", "0"), pAdjustMethod="bonferroni")
##visualize the results using a Volcano Plot
diff.res %>%
as.data.frame() %>%
EnhancedVolcano(.,
lab = rownames(.),
x = 'log2FoldChange',
y = 'padj',
xlim = c(-5, 8))
##output the results
diff.res %>%
as.data.frame() %>%
rownames_to_column('Gene') %>%
write.csv(., "bladder_cancer_diff_exp_results.csv", row.names = FALSE)
```
## Load the gene set/pathway databases of interest
We will load the Gene Ontology and WikiPathways databases. Note, an additional database called *PFOCR* is also loaded. We will ignore this database during this workshop.
```{r}
##load the pathway gene set data-bases
database_lists <- load("databases.RData")#has wp, pfocr, go
##WikiPathways annotation is a data frame that links genes (in terms of their Entrez IDs) to each of the WikiPathways (annotated by their names and IDs)
head(wp_annotation)
##WikiPathways list is a list of character vectors of Entrez IDs representing genes associated with each pathway
head(wp_list)
```
## Illustration of different enrichment analyses methods
### Over Representation Analyses (ORA)
The input to this analyses is a list of genes of interest (here it would be the list of genes deemed differentially expressed between the tumor and normal samples) and also the universe of genes from which the former list of genes were derived.
We will use a function in the *clusterProfiler* library to perform this analysis.
```{r}
##Choose set of differential expressed genes
##pick the differentially expressed genes using 0.05 threshold
diff_genes <- diff.res %>%
as.data.frame() %>%
rownames_to_column('gene') %>%
filter(padj < 0.05) %>%
.$gene
##important to pick the universe of genes. We will use all genes for which we have gene counts
universe_genes <- diff.res %>%
as.data.frame() %>%
rownames_to_column('gene') %>%
.$gene
##run the ORA analyses
res_ora <- enricher(
gene = diff_genes,
universe = universe_genes,
pAdjustMethod = "BH",
pvalueCutoff = 1, #p.adjust cutoff
qvalueCutoff = 1,
minGSSize = 1,
maxGSSize = 100000,
TERM2GENE = wp_annotation[,c("set_id","gene")],
TERM2NAME = wp_annotation[,c("set_id","name")])
res_ora <- res_ora@result
## view the first few rows of the results
head(res_ora)
#GeneRatio: Proportion of differentially expressed in each WikiPathway
#BgRatio: Proportion of all genes that are association with at least WikiPathway that is associated with each WikiPathway
##Estimate the odds ratio
#k: total number of differentially expressed genes annotated to at least one WikiPathway that are also part of each gene set
k <- sapply(res_ora$GeneRatio, function(x) as.numeric(strsplit(x, "/")[[1]][1]))
#n: total number of differentially expressed genes annotated to at least one WikiPathway
n <- sapply(res_ora$GeneRatio, function(x) as.numeric(strsplit(x, "/")[[1]][2]))
#M: total number of genes in each gene set
M <- sapply(res_ora$BgRatio, function(x) as.numeric(strsplit(x, "/")[[1]][1]))
#N: total number of genes assigned to at least one WikiPathway. Note, this number will be less than or equal to the total number of genes for which you have count data in the RNA-seq (gene expression) data set
N <- sapply(res_ora$BgRatio, function(x) as.numeric(strsplit(x, "/")[[1]][2]))
odds_ratio <- (k*(N-M-n+k))/((M-k)*(n-k))
res_ora %<>% mutate(odds_ratio=odds_ratio)
## view the first few rows of the results
head(res_ora)
res_ora %>%
write.csv(., "bladder_cancer_WikiPathways_ora.csv", row.names = FALSE)
```
### Simultaneous Enrichment Analyses (SEA)
These analyses require as input the (unadjusted) p-values associated with differential expression for each gene.
```{r}
# ##get estimates of the overall proportion of genes asssociated with the tumor vs normal comparison
TDPestimate_full <- setTDP(diff.res$pvalue, universe_genes, alpha = 0.05)
TDPestimate_full
##run rSEA method
res_rSEA <- SEA(diff.res$pvalue, universe_genes, pathlist = wp_list)
##add additional column named Name so that these results can be merged with the wp_annotation data frame
res_rSEA %<>% mutate(set_id=Name)
##get pathway names
wp_id_2_names <- wp_annotation %>%
select(1,2) %>%
unique()
res_rSEA %<>% merge(wp_id_2_names,.)
##View the first few rows of the results. Note: SC.adjP represents the adjusted p-value for the significance of self-contained null hypothesis while Comp.adjP represents the adjusted p-values for the significance of the competitive null hypothesis
res_rSEA %>%
dplyr::slice(order(Comp.adjP)) %>%
head()
res_rSEA %>% dplyr::slice(order(Comp.adjP)) %>%
write.csv(., "bladder_cancer_WikiPathways_rSEA.csv", row.names = FALSE)
```
### Significance Analyses of Function and Expression (SAFE)
These analyses require as input the normalized expression matrix of gene expression across all genes over all the 38 samples. The estimation of the significance of the association of a given gene set with the tumor vs normal comparison is based on permutation of the sample (tumor or normal) labels per subject.
```{r}
##We will use the GSEABenchmarkeR package to run this analyses. The function requires as input a list of SummarizedExperiment objects which includes additional rowData giving the differential expression results
tcga.de <- readRDS("bladder_cancer_tcga_summarized_experiment_w_de_results.rds")
##Note the function runEA takes the raw data, normalizes the expression data using the vst function in DESeq2 that generates the variance stabilized transformed normalized data which is then used as input to the SAFE method
##We will not run the analyses here because the 1000 permutations will take some time to complete
# res_safe_sample_perm <- runEA(tcga.de, method="safe", gs=wp_list, perm=1000)
# res_safe <- res_safe_sample_perm$safe[[1]]$ranking %>% as.data.frame()
# res_safe %<>% mutate(set_id=GENE.SET)
# res_safe %<>% merge(wp_id_2_names,.) %>% slice(order(PVAL))
# res_safe %>%
# write.csv(., "bladder_cancer_WikiPathways_safe_sample_perm.csv", row.names = FALSE)
##let us just read-in the results
res_safe <- read.csv("bladder_cancer_WikiPathways_safe_sample_perm.csv", header = TRUE)
##View the first few rows of the results
head(res_safe)
```
### Pathway Analysis with Down-weighting of Overlapping Genes (PADOG)
These analyses require as input the normalized expression matrix of gene expression across all genes over all the 38 samples. The estimation of the significance of the association of a given gene set with the tumor vs normal comparison is based on permutation of the sample (tumor or normal) labels per subject. This method includes the use of weights for each gene depending on its uniqueness to the gene set under consideration.
```{r}
tcga.de <- readRDS("bladder_cancer_tcga_summarized_experiment_w_de_results.rds")
##Note the function runEA takes the raw data, normalizes the expression data using the vst function in DESeq2 that generates the variance stabilized transformed normalized data which is then used as input to the SAFE method
##We will not run the analyses here because the 1000 permutations will take some time to complete
# res_padog_sample_perm <- runEA(tcga.de, method="padog", gs=wp_list, perm=1000)
# res_padog <- res_padog_sample_perm$padog[[1]]$ranking %>% as.data.frame()
# res_padog %<>% mutate(set_id=GENE.SET)
# res_padog %<>% merge(wp_id_2_names,.) %>% slice(order(PVAL))
# res_padog %>%
# write.csv(., "bladder_cancer_WikiPathways_padog_sample_perm.csv", row.names = FALSE)
##let us just read-in the results
res_padog <- read.csv("bladder_cancer_WikiPathways_padog_sample_perm.csv", header = TRUE)
##View the first few rows of the results
head(res_padog)
```
### Gene Set Enrichment Analyses (GSEA) with sample permutation
These analyses require as input the normalized expression matrix of gene expression across all genes over all the 38 samples. The estimation of the significance of the association of a given gene set with the tumor vs normal comparison is based on permutation of the sample (tumor or normal) labels per subject.
```{r}
tcga.de <- readRDS("bladder_cancer_tcga_summarized_experiment_w_de_results.rds")
##Note the function runEA takes the raw data, normalizes the expression data using the vst function in DESeq2 that generates the variance stabilized transformed normalized data which is then used as input to the SAFE method
##We will not run the analyses here because the 1000 permutations will take some time to complete
# res_gsea_sample_perm <- runEA(tcga.de, method="gsea", gs=wp_list, perm=1000)
# res_gsea <- res_gsea_sample_perm$gsea[[1]]$ranking %>% as.data.frame()
# res_gsea %<>% mutate(set_id=GENE.SET)
# res_gsea %<>% merge(wp_id_2_names,.) %>% slice(order(PVAL))
# res_gsea %>%
# write.csv(., "bladder_cancer_WikiPathways_gsea_sample_perm.csv", row.names = FALSE)
##let us just read-in the results
res_gsea <- read.csv("bladder_cancer_WikiPathways_gsea_sample_perm.csv", header = TRUE)
##View the first few rows of the results
head(res_gsea)
```
### Gene Set Enrichment Analyses (GSEA) with gene permutation
These analyses require as input a score for each gene. The larger the absolute value of the score for a gene is the more the evidence of the strength of the association of the expression of the gene with the tumor vs normal comparison. The estimation of the significance of the association of a given gene set with the tumor vs normal comparison is based on permutation of the gene labels.
```{r}
##generate a score for each gene that is equal to -log10(pvalue) in absolute value and whose sign is equal to that of the log FC - positive for up-regulated genes while negative for down-regulated genes
gene_list <- diff.res %>%
as.data.frame() %>%
rownames_to_column('Gene') %>%
mutate(Score = sign(as.numeric(log2FoldChange)) * - log10(as.numeric(as.character(pvalue)))) %>%
select(c("Score","Gene")) %>%
arrange(desc(Score))
gene_list <- unlist(split(gene_list[, 1], gene_list[, 2]))
gene_list = sort(gene_list[unique(names(gene_list))], decreasing = TRUE)
head(gene_list)
tail(gene_list)
##run the gene perm version of gsea
res_gsea_gene_perm <- clusterProfiler::GSEA(
gene_list,
pAdjustMethod="BH",
TERM2GENE = wp_annotation[,c("set_id","gene")],
TERM2NAME = wp_annotation[,c("set_id","name")] ,
minGSSize = 1,
maxGSSize = 100000,
pvalueCutoff = 1,
verbose=FALSE)
res_gsea_gene_perm <- res_gsea_gene_perm@result
##view the first few rows of the results
head(res_gsea_gene_perm)
res_gsea_gene_perm %>%
write.csv(., "bladder_cancer_WikiPathways_gsea_gene_perm.csv", row.names = FALSE)
```

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"ID","Description","setSize","enrichmentScore","NES","pvalue","p.adjust","qvalues","rank","leading_edge","core_enrichment"
"WP3888","VEGFA-VEGFR2 Signaling Pathway",403,-0.462791684122784,-1.49292146323601,0.00104166666666667,0.0363875205254516,0.0274479301702532,2506,"tags=29%, list=20%, signal=24%","6154/9209/2185/5867/301/468/6129/5970/2746/4673/2887/6595/1466/2022/6093/4641/23291/9444/3688/57758/9261/5784/4303/3142/9734/26058/6778/4855/5170/3791/8828/5578/6461/4773/10628/154796/4792/6648/4790/1432/25759/5803/2152/355/80031/3490/5587/8665/27289/5743/23189/4736/3725/51574/5908/152273/2549/6125/7414/5906/1397/2078/9252/4846/5563/11080/6886/6386/4772/22943/2308/56999/25/2534/6546/9365/781/3690/57326/154/1847/7220/4629/1839/9759/6401/5592/51309/1003/326624/6347/596/1465/1901/1827/32/10014/22899/114789/857/91624/84952/274/6722/4208/9079/1958/5579/7111/1960/9510/4929/57381/7148/10231/8013/81575/3164"
"WP4172","PI3K-Akt Signaling Pathway",252,-0.504934506863715,-1.58824388696871,0.00108813928182807,0.0363875205254516,0.0274479301702532,2187,"tags=31%, list=18%, signal=26%","5728/9180/3716/55012/5170/57521/7424/3791/5578/3672/4254/1299/10161/3566/1436/7057/4790/1435/3574/3910/2323/10681/1026/7099/6446/4170/55970/3717/1975/7450/54331/4846/5563/284/7010/1291/4609/1288/5156/10000/3570/3690/4915/3913/3678/3563/5521/3680/90993/9586/5516/3815/1292/3082/3479/5525/80310/2260/3679/1286/627/596/1902/894/2690/10319/2258/3908/1440/2252/4804/2247/5649/2788/2791/8516/3569/7148"
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",243,-0.515280852572342,-1.61626208499425,0.00109409190371991,0.0363875205254516,0.0274479301702532,2187,"tags=29%, list=18%, signal=24%","5728/9180/3716/55012/5170/57521/7424/3791/4254/2034/10161/3566/8660/1436/7057/51719/23216/1435/3910/81617/1026/55970/3717/1975/7450/54331/4846/5563/2308/284/7010/1288/5156/10000/3570/3690/3913/3678/3563/5521/3680/6515/90993/9586/5516/3815/1292/3082/3479/5525/80310/2260/3679/1286/1902/2690/10319/2258/10891/3908/1440/2252/4804/64344/2247/5649/2788/6517/2791/8516/7148"
"WP2882","Nuclear Receptors Meta-Pathway",222,-0.529042570431749,-1.64826733186755,0.00111607142857143,0.0363875205254516,0.0274479301702532,1655,"tags=22%, list=13%, signal=19%","4240/8824/4780/60482/6594/5743/3725/5465/11214/34/2040/2308/4609/8850/5552/2908/2099/80315/3726/5244/6515/4616/1028/1066/1839/5243/330/3082/10486/23764/89795/6347/2258/10891/2289/1831/2042/2949/7049/5142/1958/6649/7048/3727/6517/10252/2878/5997/5166"
"WP382","MAPK Signaling Pathway",195,-0.581705105571315,-1.79816996071903,0.00112994350282486,0.0363875205254516,0.0274479301702532,1531,"tags=23%, list=12%, signal=21%","355/1845/1844/4137/3725/5908/5602/55970/5906/9252/4772/775/7043/4609/10000/781/4915/6237/408/785/783/2260/1850/1326/5532/627/3306/9020/2316/8912/2258/2252/5533/6722/4208/120892/2247/10235/2353/8605/7048/2318/3727/1843/3164"
"WP306","Focal Adhesion",173,-0.563554095940283,-1.72444812849595,0.0011441647597254,0.0363875205254516,0.0274479301702532,2687,"tags=40%, list=22%, signal=32%","5159/2268/858/387/2889/7409/9475/7423/3915/7408/6093/3688/1793/5728/394/5170/7424/83660/3791/5578/5500/3672/2909/7057/60/4659/25759/3910/23396/54776/87/3725/5908/5602/7414/5906/7450/7791/7094/1288/2534/3611/55742/5156/10000/3690/3913/3678/3680/1292/330/3082/3479/80310/3679/1286/596/894/2316/10319/3908/857/4660/10398/4638/5649/2318/5579/8516/7148"
"WP4223","Ras Signaling",142,-0.525682204537404,-1.5751526046082,0.00118906064209275,0.0363875205254516,0.0274479301702532,3203,"tags=43%, list=26%, signal=32%","5293/2113/5601/5567/5595/5869/8503/22800/6655/805/83593/64926/5321/5159/81579/387/91860/51365/2324/808/5970/801/5900/4303/8831/22808/3791/5578/11186/1436/4790/25759/9846/8036/2114/10681/5908/5602/2549/55970/5906/54331/5336/7010/25/22821/5156/10000/4915/6237/3815/2260/10156/5320/23179/4804/10235/8605/5579/2788/2791"
"WP3929","Chemokine signaling pathway",124,-0.530461119643853,-1.57190665721361,0.00120918984280532,0.0363875205254516,0.0274479301702532,1891,"tags=27%, list=15%, signal=23%","4792/7454/3702/7852/23236/4790/25759/6363/9547/10681/3579/2770/5908/55970/9844/3717/5906/108/54331/10000/6777/6366/408/2869/5332/6376/115/196883/6387/10235/5579/2788/2791/111"
"WP289","Myometrial Relaxation and Contraction Pathways",120,-0.711645314331361,-2.09559070147585,0.00121951219512195,0.0363875205254516,0.0274479301702532,1562,"tags=40%, list=13%, signal=35%","3487/2114/5587/10681/3725/55970/108/3488/54331/4846/817/5336/6546/8787/10266/5996/6262/8786/800/408/489/58/2869/23764/10268/11142/5577/1902/467/5144/115/6263/3489/196883/59/10267/70/8490/5142/2353/3708/5579/2788/2791/111/5997/3569/1264"
"WP536","Calcium Regulation in the Cardiac Cell",107,-0.660848965792059,-1.92235988951507,0.00122699386503067,0.0363875205254516,0.0274479301702532,1596,"tags=36%, list=13%, signal=32%","2767/844/5587/10681/2770/55970/108/54331/817/775/6546/8787/5996/6262/154/8786/2701/408/489/2781/2869/11142/5577/2775/115/6263/196883/309/57165/5350/8490/845/482/3708/5579/2788/2791/111/5997"
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",100,-0.580112717768676,-1.67392091802786,0.00123456790123457,0.0363875205254516,0.0274479301702532,1241,"tags=27%, list=10%, signal=24%","3725/34/23171/4204/6640/291/3570/4915/133522/6262/2908/6095/6844/5577/627/7259/6330/3757/10891/1390/6869/4208/1958/7434/11076/3569/5354"
"WP236","Adipogenesis",104,-0.613156949875672,-1.7724263819813,0.00123609394313968,0.0363875205254516,0.0274479301702532,2137,"tags=41%, list=17%, signal=34%","6778/652/23175/1647/2034/183/6776/8660/81029/4000/355/1026/4205/3976/2487/5465/55847/2308/28999/4154/6777/2908/6095/4616/1052/1959/4692/3479/5914/25937/3977/1316/9021/5740/7025/3572/10891/4208/4209/1879/6517/3569/1675"
"WP35","G Protein Signaling Pathways",76,-0.679108269914708,-1.89534402071217,0.00131233595800525,0.0363875205254516,0.0274479301702532,1670,"tags=39%, list=14%, signal=34%","11215/5153/2767/5587/10681/2770/55970/11214/108/9465/6237/2781/9630/9472/5577/27115/9590/5144/2775/115/196883/5533/2774/5142/5136/3708/5579/2788/2791/111"
"WP2355","Corticotropin-releasing hormone signaling pathway",73,-0.644471493229881,-1.78788402195755,0.00132450331125828,0.0363875205254516,0.0274479301702532,1683,"tags=34%, list=14%, signal=30%","4790/1432/2767/10681/7099/2770/5908/4846/5563/8061/5336/6925/3726/408/2781/10411/596/2775/8912/2353/3727/5579/4929/2354/3164"
"WP2806","Human Complement System",63,-0.66087804735839,-1.79187590794092,0.00134228187919463,0.0363875205254516,0.0274479301702532,2111,"tags=44%, list=17%, signal=37%","727/5578/1604/7454/7057/11326/3384/2219/5621/966/710/716/3690/3075/22918/5627/6401/715/718/6403/5806/2162/1634/5648/5199/730/2159/1675"
"WP455","GPCRs, Class A Rhodopsin-like",58,-0.639879635527298,-1.71711321066538,0.00135869565217391,0.0363875205254516,0.0274479301702532,2170,"tags=38%, list=18%, signal=31%","4886/1131/10161/1240/7852/2857/23637/3579/6915/152/8477/5734/154/5733/1909/150/623/624/9934/5737/1910/185"
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy",56,-0.684700919154161,-1.82460654198067,0.00137741046831956,0.0363875205254516,0.0274479301702532,1778,"tags=39%, list=14%, signal=34%","83439/60/2010/4000/87/6443/775/6546/6444/781/3690/6262/3678/3680/785/783/3679/1756/3908/1674/8516/6442"
"WP2849","Hematopoietic Stem Cell Differentiation",43,-0.67034141801554,-1.73583915337319,0.00140646976090014,0.0363875205254516,0.0274479301702532,2112,"tags=47%, list=17%, signal=39%","4005/4254/79366/4773/6776/7852/1435/10320/399/3690/2313/3071/863/3757/1440/2353/947/3569/7148/2354"
"WP558","Complement and Coagulation Cascades",39,-0.745125593798936,-1.90284177138585,0.00142247510668563,0.0363875205254516,0.0274479301702532,1220,"tags=38%, list=10%, signal=35%","7450/710/716/3075/7035/5627/2157/715/718/623/1191/5648/730/2159/1675"
"WP98","Prostaglandin Synthesis and Regulation",37,-0.761060835875943,-1.93791389367576,0.00142247510668563,0.0363875205254516,0.0274479301702532,1600,"tags=46%, list=13%, signal=40%","308/3290/3248/5743/6915/5734/133522/5733/4286/1909/5740/10891/5730/309/5737/1910/5742"
"WP4149","White fat cell differentiation",30,-0.734621214684463,-1.78520995103201,0.00151745068285281,0.0363875205254516,0.0274479301702532,1825,"tags=50%, list=15%, signal=43%","6776/83439/3662/23090/2308/28999/6777/2908/6095/1052/1959/5914/9314/1879/10365"
"WP383","Striated Muscle Contraction Pathway",23,-0.821283572235296,-1.90691582895276,0.00152439024390244,0.0363875205254516,0.0274479301702532,698,"tags=52%, list=6%, signal=49%","7139/58/7431/7168/1756/7169/59/10398/70/8736/7111/1674"
"WP170","Nuclear Receptors",29,-0.793339860748143,-1.91111582812928,0.00153139356814701,0.0363875205254516,0.0274479301702532,1314,"tags=41%, list=11%, signal=37%","2494/5465/2908/6095/2099/7067/5914/4919/7025/5241/4929/3164"
"WP3893","Development and heterogeneity of the ILC family",18,-0.803262668097291,-1.74375797527922,0.0016,0.0363875205254516,0.0274479301702532,1621,"tags=56%, list=13%, signal=48%","3574/4783/374/9760/6095/3398/85480/90865/7704/3569"
"WP545","Complement Activation",15,-0.852488029806488,-1.78174120099361,0.00164203612479475,0.0363875205254516,0.0274479301702532,973,"tags=47%, list=8%, signal=43%","716/715/718/5648/5199/730/1675"
"WP2366","Butyrate-induced histone acetylation",2,0.99245902741194,1.42702316343119,0.00200400801603206,0.0427007861877601,0.0322101693265073,49,"tags=50%, list=0%, signal=50%","47"
"WP481","Insulin Signaling",150,-0.506173983161364,-1.52215372656681,0.00235571260306243,0.046028580923895,0.0347204002029001,1784,"tags=20%, list=15%, signal=17%","8660/10938/1432/2992/3799/25759/6446/3725/5602/2549/5167/9252/5563/6812/2308/4215/1326/6844/9021/6236/9020/6196/30846/6722/1958/2353/10580/5579/6517/57381"
"WP3594","Circadian rhythm related genes",138,-0.514116761839872,-1.53463022711246,0.00239520958083832,0.046028580923895,0.0347204002029001,1718,"tags=24%, list=14%, signal=21%","23373/7316/2767/355/114781/6500/3725/26224/5602/4783/5465/5563/7071/1471/6095/3398/3400/8863/23411/9099/3778/10891/1390/5730/4804/8864/1958/1408/3727/1960/3569/687/5187"
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition",15,0.817074347545397,1.88120452658206,0.00254452926208651,0.046028580923895,0.0347204002029001,675,"tags=53%, list=6%, signal=50%","991/699/701/1062/4085/9700/9232/9184"
"WP2328","Allograft Rejection",62,-0.611695546067999,-1.65863873075632,0.00267022696929239,0.046028580923895,0.0347204002029001,2744,"tags=37%, list=22%, signal=29%","3123/3127/3113/712/3115/3111/3108/842/727/1604/940/6363/355/5156/6366/5243/7431/718/6387/120892/185/730/23743"
"WP531","DNA Mismatch Repair",21,0.843167010261677,2.13563192725278,0.00272479564032698,0.046028580923895,0.0347204002029001,1385,"tags=62%, list=11%, signal=55%","5424/5985/9156/4436/5984/3978/5111/5982/6119/5983/2956/5395/5425"
"WP2361","Gastric Cancer Network 1",22,0.881905616185124,2.26199078205191,0.00280112044817927,0.046028580923895,0.0347204002029001,360,"tags=68%, list=3%, signal=66%","6790/1063/11065/56992/7153/4605/22974/144455/86/1894/4173/57122/9585/8607/286826"
"WP2363","Gastric Cancer Network 2",29,0.759734189615142,2.08343199470384,0.00286532951289398,0.046028580923895,0.0347204002029001,613,"tags=38%, list=5%, signal=36%","55215/63922/11065/7153/29089/5984/29028/84823/27101/5983/79075"
"WP4752","Base Excision Repair",30,0.781189558713735,2.14866418678642,0.00291545189504373,0.046028580923895,0.0347204002029001,1470,"tags=50%, list=12%, signal=44%","5424/23583/2237/5427/3978/5426/5111/7374/4595/10038/11284/6996/27301/5425/328"
"WP4222","Phosphodiesterases in neuronal function",31,-0.72750945670304,-1.77849793999341,0.00303030303030303,0.046028580923895,0.0347204002029001,1607,"tags=45%, list=13%, signal=39%","5153/5139/108/5140/27115/84152/5144/115/196883/8654/5142/5136/5138/111"
"WP2516","ATM Signaling Pathway",37,0.722976864053179,2.07909842918551,0.00334448160535117,0.046028580923895,0.0347204002029001,886,"tags=38%, list=7%, signal=35%","835/898/995/672/891/5888/983/993/1111/637/2177/1017/11200/5883"
"WP4290","Metabolic reprogramming in colon cancer",39,0.650339438615221,1.89824335654321,0.00334448160535117,0.046028580923895,0.0347204002029001,2135,"tags=41%, list=17%, signal=34%","5831/47/6472/2194/10606/2023/5471/2618/5723/22934/29968/5226/5230/2597/2821/9123"
"WP4754","IL-18 signaling pathway",222,-0.46719058505988,-1.4555633556707,0.00334821428571429,0.046028580923895,0.0347204002029001,2192,"tags=29%, list=18%, signal=24%","80149/5728/8698/57521/5834/5578/4254/3831/51222/4792/948/1938/8153/81618/7128/4790/7052/379/5803/56257/6363/8837/355/51341/80031/84818/770/8870/5743/3725/64332/4205/7185/22821/7078/83931/10194/7832/1112/51299/4776/58/330/11096/9208/2920/975/6347/26353/596/9021/467/10418/5806/3757/32/6869/274/59/2353/5579/1674/3569/10365/3164"
"WP466","DNA Replication",41,0.846456079198003,2.49474634065957,0.00341296928327645,0.046028580923895,0.0347204002029001,1428,"tags=76%, list=12%, signal=67%","4998/5424/4171/5985/990/8318/8317/55388/23594/81620/4173/10926/5427/5984/5426/5111/5982/6119/1017/5558/5557/23649/4176/5983/4175/4174/5001/4172/51053/5425/4999"
"WP1971","Integrated Cancer Pathway",43,0.653015909410761,1.94355049974829,0.00343642611683849,0.046028580923895,0.0347204002029001,854,"tags=33%, list=7%, signal=30%","641/672/5347/983/4436/993/1111/1869/5451/1017/1019/4312/11200/2956"
"WP4753","Nucleotide Excision Repair",43,0.666293811275025,1.98306909712394,0.00343642611683849,0.046028580923895,0.0347204002029001,498,"tags=23%, list=4%, signal=22%","5424/5985/5427/5984/3978/5426/5111/5982/6119/5983"
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM",52,0.654701382215583,2.0441135050262,0.00354609929078014,0.046028580923895,0.0347204002029001,1429,"tags=37%, list=12%, signal=32%","1020/9156/641/995/672/5888/86/675/1111/1869/637/2177/5111/11200/5591/5883/317/581/10155"
"WP45","G1 to S cell cycle control",61,0.685587337829529,2.1995751010812,0.00374531835205993,0.046028580923895,0.0347204002029001,1428,"tags=49%, list=12%, signal=44%","4998/898/4171/8318/9134/891/23594/983/4173/993/5427/1869/5426/5111/6119/1017/5558/5557/23649/1870/1019/4176/7027/4175/4174/1871/5001/4172/148327/4999"
"WP183","Proteasome Degradation",58,0.515932034207858,1.63483847206574,0.0037593984962406,0.046028580923895,0.0347204002029001,2480,"tags=41%, list=20%, signal=33%","5709/5690/6185/5717/6184/5691/5693/5688/5692/5708/5685/5686/5721/5714/7321/5687/5718/5683/5706/5704/5710/10197/7317/5695"
"WP2431","Spinal Cord Injury",90,-0.572440468952739,-1.63236239454608,0.00377833753148615,0.046028580923895,0.0347204002029001,1199,"tags=27%, list=10%, signal=24%","7099/5743/56963/4609/1464/7832/9423/7431/2920/6347/627/6403/5320/9353/388/6869/4804/1958/2353/358/6586/7538/3569/3164"
"WP707","DNA Damage Response",62,0.63345814777894,2.02657439950036,0.00395256916996047,0.046028580923895,0.0347204002029001,886,"tags=31%, list=7%, signal=29%","1020/898/995/672/9134/9133/891/5888/983/993/1111/1869/637/2177/1017/1019/11200/5591/5883"
"WP1530","miRNA Regulation of DNA Damage Response",64,0.63560810177656,2.02952026239957,0.00401606425702811,0.046028580923895,0.0347204002029001,886,"tags=31%, list=7%, signal=29%","1020/898/995/672/9134/9133/891/5888/983/993/1111/1869/637/2177/1017/1019/4176/11200/5591/5883"
"WP4016","DNA IR-damage and cellular response via ATR",75,0.760155956927704,2.53170925712447,0.00413223140495868,0.046028580923895,0.0347204002029001,1131,"tags=43%, list=9%, signal=39%","2305/55215/63967/4171/9156/8318/995/2175/672/5347/5888/83990/983/675/4436/1111/2237/55159/1869/2177/5111/1196/1017/79728/80010/11073/11200/5591/55775/5883/9521/9937"
"WP410","Exercise-induced Circadian Regulation",44,-0.639139699850929,-1.66231682685446,0.00418410041841004,0.046028580923895,0.0347204002029001,1205,"tags=23%, list=10%, signal=21%","50486/5813/5516/11030/2674/8864/1408/7122/687/5187"
"WP1541","Energy Metabolism",42,-0.64632675153625,-1.66464566680558,0.00422535211267606,0.046028580923895,0.0347204002029001,1322,"tags=31%, list=11%, signal=28%","1432/4205/5465/5563/2308/133522/51422/5532/23411/10891/5533/4208/4209"
"WP4022","Pyrimidine metabolism",79,0.591516775875115,1.97457796170619,0.00423728813559322,0.046028580923895,0.0347204002029001,1906,"tags=35%, list=16%, signal=30%","5424/4830/7083/5427/6241/5437/5426/5558/1841/790/5557/7298/54963/23649/87178/5436/7371/5433/84172/10201/1890/79077/129607/5425/25885/5422/7372/5439"
"WP1528","Physiological and Pathological Hypertrophy of the Heart",24,-0.720931513879714,-1.69304310836266,0.00451807228915663,0.0481348470806302,0.0363092044290522,2941,"tags=79%, list=24%, signal=60%","6774/5606/805/5581/5530/387/1489/801/183/50804/1432/3725/817/4776/3977/5532/3572/2353/5579"
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)",21,-0.764734878027421,-1.72266026175418,0.0047244094488189,0.0493233618233618,0.0372057279952017,1433,"tags=38%, list=12%, signal=34%","3248/5743/6915/5740/5730/5737/8309/5742"
"WP2446","Retinoblastoma Gene in Cancer",86,0.778790413293543,2.60647947921743,0.00480769230769231,0.0493233618233618,0.0372057279952017,854,"tags=50%, list=7%, signal=47%","24137/4998/898/5985/7272/7153/8318/8317/9134/9133/891/2189/81620/983/4173/10733/993/6502/890/1111/54443/5427/6241/1869/5984/1786/5426/5111/6119/1017/3925/5557/7298/1870/1019/4176/5983/7027/10592/4175/5928/5591/2956"
"WP179","Cell Cycle",115,0.67352923441135,2.39594113780755,0.00546448087431694,0.0546566692975533,0.0412287625140199,779,"tags=36%, list=6%, signal=34%","4998/898/4171/7272/990/8318/8317/991/995/5347/699/9134/9133/891/23594/983/9088/4173/10926/993/6502/890/1111/5933/1869/9700/5111/9232/1017/1870/3066/1019/4176/7027/10459/4175/9184/2932/11200/4174/5591"
"WP411","mRNA Processing",122,0.492406310910327,1.76034403509172,0.00552486187845304,0.0546566692975533,0.0412287625140199,2226,"tags=34%, list=18%, signal=28%","51692/9343/6628/6632/1196/3191/5496/6636/6635/10772/6637/5725/56339/29894/6626/1478/4841/55660/51690/6627/1659/11338/9410/53981/6625/8683/10236/57819/3181/10898/6634/6426/1477/8106/1479/23450/8175/6629/8449/3276/6633/1660"
"WP408","Oxidative Stress",29,-0.705190779022085,-1.69876912319646,0.00612557427258806,0.0595362832809435,0.0449095657657887,1847,"tags=34%, list=15%, signal=29%","6648/4790/1432/4780/5602/3726/4784/2353/6649/2878"
"WP1984","Integrated Breast Cancer Pathway",143,0.412990391457822,1.49046424149869,0.00625,0.059698275862069,0.0450317604355717,854,"tags=16%, list=7%, signal=15%","6790/8438/641/79902/672/5347/5888/26284/675/4436/993/1111/7517/1869/637/1017/1019/6597/4312/55526/27005/11200/2956"
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement",17,-0.775809358119203,-1.66309595715165,0.00644122383252818,0.0602785434498767,0.0454694694083242,1404,"tags=47%, list=11%, signal=42%","87/3725/7414/3690/4026/8076/4638/3708"
"WP554","ACE Inhibitor Pathway",11,-0.85530951024262,-1.68934168839734,0.00661157024793388,0.0602785434498767,0.0454694694083242,308,"tags=55%, list=3%, signal=53%","4846/623/624/4306/185/1511"
"WP2338","miRNA Biogenesis",6,0.879053726567659,1.64496424677402,0.00663716814159292,0.0602785434498767,0.0454694694083242,571,"tags=50%, list=5%, signal=48%","6895/57510/5901"
"WP2276","Glial Cell Differentiation",5,-0.920932317124545,-1.55415561317042,0.0072992700729927,0.0636867012817811,0.0480403199864471,77,"tags=80%, list=1%, signal=80%","4155/4478/11076/5354"
"WP1591","Heart Development",30,-0.681766389246273,-1.65676694061222,0.00758725341426404,0.0636867012817811,0.0480403199864471,2090,"tags=53%, list=17%, signal=44%","4089/650/7423/652/7424/4773/23493/657/5308/6910/4772/4776/9464/2627/6722/4208"
"WP1600","Nicotine Metabolism",1,-0.995107233140341,-1.33374921644582,0.00760456273764259,0.0636867012817811,0.0480403199864471,62,"tags=100%, list=1%, signal=100%",""
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity",14,0.758935770206651,1.72082838746272,0.00767263427109974,0.0636867012817811,0.0480403199864471,487,"tags=21%, list=4%, signal=21%","6659/1869/1019"
"WP3298","Melatonin metabolism and effects",26,-0.695722684462236,-1.6436047371393,0.00769230769230769,0.0636867012817811,0.0480403199864471,542,"tags=23%, list=4%, signal=22%","2308/8863/23411/8864/1408/5187"
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway",82,-0.560787242557001,-1.58608821561989,0.00770218228498074,0.0636867012817811,0.0480403199864471,3220,"tags=43%, list=26%, signal=32%","7189/3601/5601/5595/915/7040/3937/916/9051/7409/2185/8915/5970/920/10019/5170/4773/4792/7454/940/3702/4790/1432/9846/355/3662/3725/4772/2534/7431/1326/9020/2353/3708/3569"
"WP24","Peptide GPCRs",21,-0.72515909137611,-1.63351088861753,0.0078740157480315,0.0641500694766095,0.0483898491016796,1762,"tags=52%, list=14%, signal=45%","728/4886/7852/10396/3579/1909/623/6869/624/1910/185"
"WP4589","Major receptors targeted by epinephrine and norepinephrine",11,-0.832489389521898,-1.64426913769363,0.00826446280991736,0.0655698899278021,0.0494608517980951,1354,"tags=64%, list=11%, signal=57%","152/108/154/150/115/196883/111"
"WP474","Endochondral Ossification",54,-0.605621683222306,-1.60708674739698,0.00829875518672199,0.0655698899278021,0.0494608517980951,1766,"tags=41%, list=14%, signal=35%","55553/51719/657/5727/4921/2487/5167/9507/7078/6777/1028/9759/3479/7067/11096/2260/2690/4256/4208/2247/5745/9510"
"WP4352","Ciliary landscape",197,0.362614716331557,1.39055119188859,0.00840336134453781,0.0655698899278021,0.0494608517980951,2047,"tags=20%, list=17%, signal=17%","128239/4171/9343/55388/4173/4436/84515/25804/10238/3066/4176/79989/10051/4175/89891/4174/25904/54512/57560/150737/4172/116225/4704/7022/5714/100616408/284086/63929/7020/2717/57414/5718/54903/11018/90410/5706/6629/5704/100616387"
"WP2525","Trans-sulfuration and one carbon metabolism",28,0.618571121288761,1.68827533226606,0.00864553314121038,0.0665225744476465,0.0501794832903585,1790,"tags=46%, list=15%, signal=40%","6472/25902/1786/1789/7298/191/1788/5723/4522/29968/10797/2730/1719"
"WP3527","Preimplantation Embryo",31,-0.666639128694346,-1.62969196644526,0.00909090909090909,0.0678565179352581,0.0511857070497767,228,"tags=26%, list=2%, signal=25%","5087/83439/3662/9314/4306/1958/7538/2354"
"WP2406","Cardiac Progenitor Differentiation",30,-0.667798781954949,-1.62282412623367,0.00910470409711684,0.0678565179352581,0.0511857070497767,1210,"tags=53%, list=10%, signal=48%","652/3791/7852/1432/6910/22943/4920/5156/3815/7139/3479/70/4208/2247/4684/64321"
"WP1544","MicroRNAs in cardiomyocyte hypertrophy",76,-0.564283495089114,-1.57487604817129,0.00918635170603675,0.0678565179352581,0.0511857070497767,2402,"tags=46%, list=20%, signal=37%","6774/5293/5606/5595/8503/5330/805/7040/5530/387/9475/1489/6093/801/9734/5170/183/50804/4790/1432/3976/817/4776/9759/3479/5592/5532/9020/5320/3572/1827/10014/2247/4638/5579"
"WP167","Eicosanoid Synthesis",18,-0.747061129454138,-1.62175320009889,0.0096,0.0698524776194679,0.0526913046075029,458,"tags=33%, list=4%, signal=32%","5743/5740/5320/5730/4056/5742"
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS",16,-0.762435441713953,-1.61661376948339,0.00970873786407767,0.0698524776194679,0.0526913046075029,658,"tags=69%, list=5%, signal=65%","4155/650/2736/652/55553/3976/3479/2920/2247/6663/5354"
"WP428","Wnt Signaling",93,-0.516013726346037,-1.47939174505811,0.0099626400996264,0.0707602899383721,0.0533760879831536,1778,"tags=28%, list=14%, signal=24%","83439/81029/6423/23236/3725/85407/817/5176/4772/8061/22943/23500/4609/4920/4776/5332/5532/4919/7482/8324/894/5533/6422/166336/5579/64321"
"WP465","Tryptophan metabolism",27,-0.673088908977646,-1.6060772897894,0.0107197549770291,0.0744766660265028,0.0561794345668281,796,"tags=37%, list=6%, signal=35%","223/4967/8854/216/38/4129/11185/217/316/23498"
"WP334","GPCRs, Class B Secretin-like",4,-0.926494114951996,-1.50086921601437,0.0109689213893967,0.0744766660265028,0.0561794345668281,135,"tags=75%, list=1%, signal=74%","10203/5745/7434"
"WP2858","Ectoderm Differentiation",112,-0.512859193219582,-1.49738516820973,0.0109756097560976,0.0744766660265028,0.0561794345668281,2546,"tags=39%, list=21%, signal=31%","5236/1004/4926/51762/79776/54521/5292/10257/5362/652/51222/83439/657/345557/50937/1896/5452/6907/23229/6622/56963/4204/6781/6386/4772/4609/4920/2534/8835/10253/8322/5010/91653/51422/79658/10486/55843/6347/1756/8848/2627/9079/7704/114815"
"WP4482","Vitamin D in inflammatory diseases",21,-0.697303771819546,-1.57076332281756,0.0110236220472441,0.0744766660265028,0.0561794345668281,1891,"tags=48%, list=15%, signal=40%","5530/4089/5970/4792/4790/1432/4772/2908/3569/1843"
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome",22,0.683736816044692,1.75370963384132,0.0112044817927171,0.0747865411224731,0.0564131803640924,2889,"tags=55%, list=24%, signal=42%","11335/23028/1869/3066/5928/6839/6720/9219/57504/10951/9112/51176"
"WP247","Small Ligand GPCRs",10,-0.821064222173243,-1.58944551939811,0.0118043844856661,0.0778527262507026,0.0587260731931008,1626,"tags=90%, list=13%, signal=78%","8698/1903/6915/9294/5734/5733/1902/1901/5737"
"WP2795","Cardiac Hypertrophic Response",51,-0.582834347182136,-1.53056492528391,0.0125523012552301,0.0818114693576175,0.061712242703732,2310,"tags=33%, list=19%, signal=27%","801/9734/5170/5578/4773/4790/1432/5587/4205/817/9759/3479/5592/9020/5320/10014/2247"
"WP2895","Differentiation of white and brown adipocyte ",18,-0.723465431235367,-1.57053061926027,0.0128,0.0824558139534884,0.0621982864137087,1182,"tags=56%, list=10%, signal=50%","655/650/652/23090/63976/133522/253738/4093/10891/27129"
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation",9,-0.852789090889178,-1.62482138493552,0.0134453781512605,0.0854001096190737,0.0644192352627252,1322,"tags=89%, list=11%, signal=79%","4205/817/894/6722/9314/4208/4209/93649"
"WP3878","ATM Signaling Network in Development and Disease ",41,0.549013693025727,1.61809919652966,0.0136518771331058,0.0854001096190737,0.0644192352627252,779,"tags=20%, list=6%, signal=18%","1020/699/983/9212/1111/3150/11200/5591"
"WP2197","Endothelin Pathways",23,-0.671337050093026,-1.55875910667561,0.013719512195122,0.0854001096190737,0.0644192352627252,2310,"tags=52%, list=19%, signal=42%","801/4886/5578/23236/10681/2770/4846/1909/10267/4638/1910/1264"
"WP49","IL-2 Signaling Pathway",41,-0.603580080557865,-1.55468156464178,0.0141043723554302,0.0868202476100925,0.0654904774866173,1825,"tags=29%, list=15%, signal=25%","3716/6776/9846/4137/3725/4609/2534/6777/596/9021/894/2353"
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease",23,-0.668402451934719,-1.55194534359928,0.0152439024390244,0.0928035379254891,0.0700038087714596,395,"tags=35%, list=3%, signal=34%","2200/4052/2022/1432/2316/7049/7048/185"
"WP185","Integrin-mediated Cell Adhesion",87,-0.520619938572016,-1.48375056211518,0.0163316582914573,0.098344985798558,0.0741838483033014,2709,"tags=33%, list=22%, signal=26%","3684/858/2889/3683/9475/7408/825/6093/3688/1793/5170/3672/5908/5602/7414/5906/7791/7094/2534/3611/10000/3690/3678/3680/3679/7145/857/10580/8516"
"WP4481","Resistin as a regulator of inflammation",28,-0.655231246365445,-1.57139210846378,0.016793893129771,0.10004104079455,0.0754632209679579,1891,"tags=39%, list=15%, signal=33%","4792/23236/113026/4790/1432/5336/10000/5332/84812/3708/3569"
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation",11,-0.794035539572439,-1.56831804511128,0.0181818181818182,0.10715667311412,0.0808307034510842,1121,"tags=45%, list=9%, signal=41%","22943/2308/4093/1634/6422"
"WP3599","Transcription factor regulation in adipogenesis",19,-0.689736241592773,-1.52221495678199,0.0188679245283019,0.10743374272786,0.081039703330725,1104,"tags=42%, list=9%, signal=38%","23175/8660/2308/2908/1052/10891/6517/3569"
"WP4249","Hedgehog Signaling Pathway",34,-0.613979531009327,-1.52772199875654,0.0194319880418535,0.10743374272786,0.081039703330725,1663,"tags=59%, list=14%, signal=51%","1453/5567/51684/1452/2619/2736/374654/5727/50937/2121/2735/64839/132884/8643/8405/8452/408/91653/596/894"
"WP516","Hypertrophy Model",15,-0.733841554420393,-1.53376433075407,0.0197044334975369,0.10743374272786,0.081039703330725,1051,"tags=40%, list=9%, signal=37%","9948/1839/6935/467/3727/8013"
"WP3624","Lung fibrosis",42,-0.595090254201187,-1.53268360107275,0.0197183098591549,0.10743374272786,0.081039703330725,1198,"tags=33%, list=10%, signal=30%","4502/4780/4204/4092/2006/3082/3479/2920/6347/5806/1440/2252/2247/3569"
"WP4204","Tumor suppressor activity of SMARCB1",26,0.611731763503002,1.63934021100858,0.0198863636363636,0.10743374272786,0.081039703330725,1153,"tags=35%, list=9%, signal=31%","86/2146/1019/6597/6598/5928/6602/6603/23512"
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)",12,-0.780021355445463,-1.56202213498319,0.0199004975124378,0.10743374272786,0.081039703330725,1825,"tags=58%, list=15%, signal=50%","6776/374/8061/4609/2099/7431/5241"
"WP2029","Cell Differentiation - Index",6,-0.881008856885747,-1.52128807927282,0.02,0.10743374272786,0.081039703330725,366,"tags=83%, list=3%, signal=81%","4205/10014/6722/4208/4209"
"WP4284","Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer",2,0.969356206570633,1.39380440117446,0.0200400801603206,0.10743374272786,0.081039703330725,117,"tags=50%, list=1%, signal=50%","9134"
"WP2911","miRNA targets in ECM and membrane receptors",22,-0.670621722009888,-1.53460715356793,0.0201550387596899,0.10743374272786,0.081039703330725,2366,"tags=41%, list=19%, signal=33%","3915/3672/7057/3910/1291/3913/1292/6383/7148"
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling",9,-0.821314343290443,-1.56485246233761,0.0201680672268908,0.10743374272786,0.081039703330725,1720,"tags=67%, list=14%, signal=57%","23236/2770/6262/7220/6263/3708"
"WP4521","Glycosylation and related congenital defects",25,0.625791964921431,1.6442405464169,0.0205882352941176,0.107777907474417,0.0812993145873906,3238,"tags=56%, list=26%, signal=41%","7841/10195/79053/8818/29929/79644/8813/5373/1798/9526/4247/22845/54344/79087"
"WP4540","Pathways Regulating Hippo Signaling",80,-0.514765914067745,-1.45131657449357,0.02088772845953,0.107777907474417,0.0812993145873906,2054,"tags=36%, list=17%, signal=30%","5159/387/2771/1004/2324/5573/3791/5578/83439/1436/23236/2767/7005/1012/5563/7003/7010/5156/4915/3815/51422/2260/26524/5332/1003/5577/4804/2774/5579"
"WP404","Nucleotide Metabolism",18,0.676170913550093,1.62381396176178,0.0212201591511936,0.107777907474417,0.0812993145873906,3354,"tags=61%, list=27%, signal=44%","5424/6241/3251/10797/1719/5422/6723/4831/5423/3614/6240"
"WP3591","Sleep regulation",13,-0.762190632381489,-1.54820277261946,0.021630615640599,0.107777907474417,0.0812993145873906,1424,"tags=46%, list=12%, signal=41%","114781/1471/8863/5730/2353/3569"
"WP4493","Cells and Molecules involved in local acute inflammatory response ",13,-0.763202044338344,-1.5502572072049,0.021630615640599,0.107777907474417,0.0812993145873906,531,"tags=69%, list=4%, signal=66%","3683/3688/6404/727/7412/718/6403/730/3569"
"WP3931","ESC Pluripotency Pathways",83,-0.513192199879881,-1.45271763765166,0.021656050955414,0.107777907474417,0.0812993145873906,1374,"tags=23%, list=11%, signal=20%","81029/657/3725/2549/3976/4092/5156/10000/8322/4093/2260/3977/7482/8324/3572/2258/2252/2247/2353"
"WP366","TGF-beta Signaling Pathway",128,-0.468666885625339,-1.39109929248597,0.0216867469879518,0.107777907474417,0.0812993145873906,1465,"tags=17%, list=12%, signal=15%","1026/6500/3725/4205/7071/4092/4609/3690/3726/10413/7041/6935/1316/467/9839/857/4208/7049/2353/7048/3727/2354"
"WP4659","Gastrin Signaling Pathway",105,-0.485368268009291,-1.40931408025564,0.02203182374541,0.107777907474417,0.0812993145873906,2080,"tags=27%, list=17%, signal=22%","5970/6093/3688/960/5578/4792/10524/8649/4790/1432/5587/1026/5743/3725/3717/2308/4609/2534/6925/408/3815/330/388/9314/4208/1958/2353/4209"
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)",56,-0.552922911614378,-1.47344151807024,0.0220385674931129,0.107777907474417,0.0812993145873906,1683,"tags=50%, list=14%, signal=43%","55806/4089/2619/10468/2736/864/26018/1523/652/4254/4790/27122/657/3516/3725/3488/4772/22943/6925/2908/1959/4345/3479/4487/2353/947/6422/2354"
"WP2884","NRF2 pathway",96,-0.50229588517062,-1.43999197856862,0.0225,0.107777907474417,0.0812993145873906,787,"tags=14%, list=6%, signal=13%","6515/1066/1839/3082/23764/2258/2042/2949/1958/6649/7048/6517/2878"
"WP186","Homologous recombination",12,0.753764556637835,1.65493057410169,0.0225563909774436,0.107777907474417,0.0812993145873906,522,"tags=33%, list=4%, signal=32%","5424/5888/675/25788"
"WP3413","NOTCH1 regulation of human endothelial cell calcification",16,-0.719108393262633,-1.52474618399967,0.0226537216828479,0.107777907474417,0.0812993145873906,2245,"tags=38%, list=18%, signal=31%","28514/2702/3672/55553/1902/4256"
"WP1533","Vitamin B12 Metabolism",30,-0.628971424933689,-1.52846939927905,0.0227617602427921,0.107777907474417,0.0812993145873906,1854,"tags=37%, list=15%, signal=31%","3043/6648/4790/3039/3949/6948/4524/6347/12/6649/3569"
"WP241","One Carbon Metabolism",25,0.608137785972,1.59785497665971,0.0235294117647059,0.110468594217348,0.0833289604869602,961,"tags=36%, list=8%, signal=33%","6472/25902/1786/1789/7298/2618/191/1788/4522"
"WP4756","Renin Angiotensin Aldosterone System (RAAS)",28,-0.642313201374039,-1.54041172700475,0.0244274809160305,0.113215258855586,0.0854008317797218,2977,"tags=57%, list=24%, signal=43%","5330/805/10488/1636/91860/468/808/801/183/8536/817/90993/9586/3708/185/1511"
"WP304","Kit receptor signaling pathway",59,-0.547763539132581,-1.46610882741393,0.0245231607629428,0.113215258855586,0.0854008317797218,2042,"tags=42%, list=17%, signal=35%","6774/2309/5595/6194/7006/3635/7409/6615/2887/5578/4254/6776/1432/9846/4137/3717/695/2534/6777/3726/4286/3815/596/2353/5579"
"WP4496","Signal transduction through IL1R",30,-0.61959163714888,-1.5056754884073,0.0257966616084977,0.118110334967833,0.0890932984651901,2594,"tags=47%, list=21%, signal=37%","7189/5606/7040/7042/5970/54472/4792/4790/1432/3725/7043/11213/9020/3569"
"WP2023","Cell Differentiation - Index expanded",11,-0.778736061181117,-1.53809968982857,0.0264462809917355,0.120092128437881,0.0905882101269975,688,"tags=64%, list=6%, signal=60%","4205/3398/10014/6722/9314/4208/4209"
"WP4191","Caloric restriction and aging",8,-0.836380477237547,-1.55342529938321,0.0271186440677966,0.122144136695604,0.0921360863920861,658,"tags=38%, list=5%, signal=36%","3479/23411/10891"
"WP2848","Differentiation Pathway",26,-0.627651287352175,-1.48278998543939,0.0276923076923077,0.123722084367246,0.0933263680292543,2090,"tags=58%, list=17%, signal=48%","652/4254/1436/1435/2323/22943/7043/4907/3570/3815/3082/3479/7482/2247/3569"
"WP1539","Angiogenesis",24,-0.646934398249501,-1.51926750798385,0.0286144578313253,0.124077782462057,0.0935946791515044,2054,"tags=38%, list=17%, signal=31%","3791/1432/7077/4846/284/7010/7078/5156/2247"
"WP1992","Genes targeted by miRNAs in adipocytes",10,-0.782703487687222,-1.51518543607815,0.0286677908937605,0.124077782462057,0.0935946791515044,1235,"tags=70%, list=10%, signal=63%","3784/58155/2078/9759/3479/9464/6722"
"WP2855","Dopaminergic Neurogenesis",10,-0.782640519459834,-1.515063539929,0.0286677908937605,0.124077782462057,0.0935946791515044,1529,"tags=60%, list=12%, signal=53%","216/2735/6571/1028/4487/4929"
"WP3892","Development of pulmonary dendritic cells and macrophage subsets",10,-0.78684563200572,-1.52320394735892,0.0286677908937605,0.124077782462057,0.0935946791515044,1654,"tags=70%, list=13%, signal=61%","1435/10320/2323/3662/3394/6925/3398"
"WP3299","let-7 inhibition of ES cell reprogramming",5,-0.870618600337099,-1.46924671822705,0.0291970802919708,0.125389011486448,0.0945837688772942,1060,"tags=60%, list=9%, signal=55%","4609/9314/1958"
"WP3287","Overview of nanoparticle effects",15,-0.713421200746702,-1.49108480423036,0.0295566502463054,0.125907407654978,0.094974806838355,1407,"tags=33%, list=11%, signal=30%","5743/10000/596/5742/3569"
"WP3947","Serotonin and anxiety",7,-0.851912216031474,-1.51661298422642,0.0297723292469352,0.125907407654978,0.094974806838355,435,"tags=57%, list=4%, signal=55%","5341/84812/2353/5579"
"WP2881","Estrogen Receptor Pathway",10,-0.781205151773883,-1.51228490376935,0.03035413153457,0.127395370228423,0.0960972106796195,1374,"tags=40%, list=11%, signal=36%","3725/5465/2099/5166"
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)",11,-0.764891615812808,-1.51075520408002,0.031404958677686,0.129485796476088,0.0976740665039081,1060,"tags=45%, list=9%, signal=42%","7040/3688/4609/9839/6422"
"WP477","Cytoplasmic Ribosomal Proteins",85,-0.501189342497575,-1.42462469075787,0.0314465408805031,0.129485796476088,0.0976740665039081,3956,"tags=54%, list=32%, signal=37%","6135/9349/6235/6205/6152/7311/6233/6217/6202/6157/9045/6130/6137/6176/6194/6181/23521/6229/6192/2197/6124/6160/6210/6154/6129/6224/6230/6191/6136/6206/6208/6168/6232/6134/6146/4736/6189/6125/6164/6228/6133/6122/6138/6207/6203/6196"
"WP3875","ATR Signaling",8,0.781003687085597,1.5506309557775,0.0315533980582524,0.129485796476088,0.0976740665039081,2500,"tags=75%, list=20%, signal=60%","1111/11073/5883/3364/545/5810"
"WP15","Selenium Micronutrient Network",50,-0.555900230371387,-1.45738739720432,0.0321678321678322,0.131036610448375,0.0988438805776267,1854,"tags=26%, list=15%, signal=22%","3043/6648/4790/3039/3949/5743/4524/6347/12/6649/5742/2878/3569"
"WP2374","Oncostatin M Signaling Pathway",64,-0.52821348511576,-1.43895010938035,0.0345285524568393,0.139626409205029,0.105323360164158,2153,"tags=30%, list=18%, signal=25%","9180/3716/5578/4792/4790/1432/3949/3717/7078/6777/3726/3977/6347/9021/3572/1958/2353/3727/5579"
"WP23","B Cell Receptor Signaling Pathway",92,-0.492094428626572,-1.41127496856742,0.0347826086956522,0.139634530560807,0.105329486286605,2628,"tags=32%, list=21%, signal=25%","2889/7409/8915/5970/7462/5788/5170/4773/4792/8462/4790/1432/9846/23396/3662/3725/2549/2308/695/5336/4609/2534/974/975/8395/933/4208/4209/5579"
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway",45,-0.551646144759052,-1.43634135631229,0.0361613351877608,0.144125033769924,0.108716774475888,3262,"tags=51%, list=27%, signal=38%","6774/3055/5601/5595/6194/7006/4791/5970/6778/3716/4792/6776/4790/1432/9846/2242/3717/695/4609/2534/6777/85480/3569"
"WP206","Fatty Acid Omega Oxidation",5,-0.866595883894327,-1.46245802461355,0.0364963503649635,0.144421272158498,0.108940233796169,1529,"tags=80%, list=12%, signal=70%","216/126/217/125"
"WP2636","Common Pathways Underlying Drug Addiction",24,-0.629302655429802,-1.47786093871257,0.0376506024096386,0.147932154148509,0.111588571531366,2310,"tags=38%, list=19%, signal=30%","801/5578/5500/60/2770/5908/5906/5579/72"
"WP4211","Transcriptional cascade regulating adipogenesis",13,-0.731843560040142,-1.48656016046487,0.0382695507487521,0.149305148695836,0.11262425238884,1050,"tags=31%, list=9%, signal=28%","28999/1052/1959/10365"
"WP286","IL-3 Signaling Pathway",44,-0.554662346420084,-1.44260253570813,0.0390516039051604,0.151290829115097,0.1141220960644,3262,"tags=45%, list=27%, signal=33%","6774/3055/5293/5595/1439/7040/3635/2889/7409/3716/6776/9846/3725/3717/969/2534/6777/3563/596/2353"
"WP4541","Hippo-Merlin Signaling Dysregulation",95,-0.481263972980716,-1.37790961849811,0.0401002506265664,0.154274575327207,0.116372803353413,2080,"tags=36%, list=17%, signal=30%","3684/5159/3683/1004/2324/5573/3688/960/3791/5500/3672/154796/1436/4659/7005/1012/7003/7010/4609/5156/3690/4915/3678/3680/3815/2260/26524/5332/1003/3679/5577/94274/4804/8516"
"WP34","Ovarian Infertility Genes",17,-0.674814596859437,-1.44659434192003,0.0418679549114332,0.159964462213338,0.120664813791934,834,"tags=29%, list=7%, signal=27%","2701/6609/894/1958/5241"
"WP4217","Ebola Virus Pathway on Host",118,-0.458831175424282,-1.34852633592062,0.0428921568627451,0.162755170561375,0.122769908251693,2744,"tags=28%, list=22%, signal=22%","3123/3127/3113/858/387/4791/1212/3115/3111/55823/5970/3108/3688/3672/60/153090/4790/4240/3384/7099/87/30835/3690/3678/558/9021/2316/388/857/2621/10462/2934/2318"
"WP1601","Fluoropyrimidine Activity",28,0.540549228053908,1.47532902230794,0.0432276657060519,0.162912427218726,0.122888530507,1259,"tags=36%, list=10%, signal=32%","23583/7083/7517/6241/8836/7298/5471/7371/6996/1890"
"WP4030","SCFA and skeletal muscle substrate metabolism",2,-0.954183281997241,-1.37242059985368,0.0437375745526839,0.163690853066565,0.123475714739552,115,"tags=100%, list=1%, signal=99%","6517"
"WP1424","Globo Sphingolipid Metabolism",20,-0.635512972937628,-1.41849909401341,0.0440251572327044,0.163690853066565,0.123475714739552,2880,"tags=45%, list=23%, signal=34%","6483/81849/26301/6482/53947/27090/256435/6489/30815"
"WP4396","Nonalcoholic fatty liver disease",135,-0.448303650812215,-1.33218564897561,0.0445783132530121,0.163734880411581,0.123508925562223,1894,"tags=19%, list=15%, signal=16%","7386/4714/8660/4790/6392/7412/355/7385/22877/1350/4724/3725/5465/5563/4092/10000/3570/7381/51422/3953/6347/9021/84701/1346/3569"
"WP4210","Tryptophan catabolism leading to NAD+ production",11,-0.746472837499919,-1.47437584703945,0.0446280991735537,0.163734880411581,0.123508925562223,17,"tags=18%, list=0%, signal=18%","349565/23498"
"WP530","Cytokines and Inflammatory Response",14,-0.714034062158728,-1.4716310345101,0.0458265139116203,0.167025583598932,0.125991177443998,2929,"tags=64%, list=24%, signal=49%","7040/3123/920/3600/1435/3574/2920/1440/3569"
"WP716","Vitamin A and Carotenoid Metabolism",22,-0.629472273219803,-1.44044342995728,0.048062015503876,0.173368799874824,0.130776009025851,1885,"tags=45%, list=15%, signal=39%","5915/4023/6257/948/8854/216/116362/5947/5914/83875"
"WP4239","Epithelial to mesenchymal transition in colorectal cancer",128,-0.447616590432949,-1.32861770557018,0.0481927710843374,0.173368799874824,0.130776009025851,1093,"tags=15%, list=9%, signal=14%","7043/1288/10000/5310/7483/8322/3678/5010/3398/26524/6935/1286/7482/8324/9839/117581/4209/7048/7122"
"WP2064","Neural Crest Differentiation",64,-0.507296714214776,-1.38196900112776,0.049136786188579,0.175624384183695,0.132477447313181,2616,"tags=41%, list=21%, signal=32%","1488/4791/6615/1004/8313/3688/28514/9734/4855/652/83439/23493/4790/3516/4609/6925/4286/9759/2260/4487/4359/10014/388/5376/2247/6663"
"WP4595","Urea cycle and associated pathways",16,0.640253061310679,1.49763620923435,0.0494791666666667,0.175714476495726,0.132545405982906,864,"tags=25%, list=7%, signal=23%","5831/10165/162417/10166"
"WP4008","NO/cGMP/PKG mediated Neuroprotection",25,-0.609319937888644,-1.43717569726893,0.0498489425981873,0.175900090442011,0.132685418782973,2621,"tags=48%, list=21%, signal=38%","1742/5970/801/842/4792/4790/5139/4846/817/596/4881/5138"
"WP4585","Cancer immunotherapy by PD-1 blockade",21,-0.620866606987424,-1.3985791186433,0.0519685039370079,0.182218678361407,0.137451672638189,4417,"tags=81%, list=36%, signal=52%","5781/80380/925/10725/3932/926/7535/5133/6774/915/3123/916/4773/4790/3725/4772/4776"
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR",27,-0.602719596112229,-1.43816699772577,0.0551301684532925,0.190946691176471,0.144035410216718,2399,"tags=41%, list=20%, signal=33%","5970/9734/4773/4792/4790/4772/4776/9759/5532/10014/5533"
"WP2877","Vitamin D Receptor Pathway",118,-0.451549634647416,-1.32712554619747,0.0551470588235294,0.190946691176471,0.144035410216718,1468,"tags=23%, list=12%, signal=20%","7077/3662/1026/3394/3488/50486/2308/4609/5734/7078/6546/78989/6304/9365/154/3726/4345/5243/3400/11096/7168/7869/79689/623/9314/6422/6517"
"WP3995","Prion disease pathway",31,-0.584578945178294,-1.42908444719709,0.0575757575757576,0.197162702795572,0.148724288447354,1683,"tags=32%, list=14%, signal=28%","4790/5452/3662/5621/2534/2260/596/4208/1879/4684"
"WP2943","Hypoxia-mediated EMT and Stemness",2,-0.941315874717716,-1.35391315463816,0.0576540755467197,0.197162702795572,0.148724288447354,539,"tags=100%, list=4%, signal=96%","6935"
"WP2485","NAD Biosynthesis II (from tryptophan)",6,-0.837613690804246,-1.44635517894852,0.0581818181818182,0.197746793084216,0.149164880969854,17,"tags=33%, list=0%, signal=33%","64802/23498"
"WP4462","Platelet-mediated interactions with vascular and circulating cells",15,-0.686870057317304,-1.43559163068704,0.0607553366174056,0.205234490768553,0.154813020777343,2929,"tags=60%, list=24%, signal=46%","7040/7042/6404/7412/7099/7043/6401/6347/6403"
"WP4747","Netrin-UNC5B signaling Pathway",44,-0.539244900584092,-1.40250382231845,0.0627615062761506,0.210726511981742,0.158955776661128,2884,"tags=39%, list=24%, signal=30%","3635/23365/387/2185/3791/5578/1432/7412/3725/56963/54538/2534/9423/10413/6401/1003/6347"
"WP3297","EV release from cardiac cells and their functional effects",4,-0.862950715278098,-1.39793242352714,0.0639853747714808,0.213541551948195,0.161079225011274,265,"tags=50%, list=2%, signal=49%","6387/10365"
"WP4538","Regulatory circuits of the STAT3 signaling pathway",67,-0.493240817393167,-1.35894337979665,0.064388961892247,0.213601705917993,0.161124600511958,2221,"tags=31%, list=18%, signal=26%","5788/9180/3716/57521/1432/3587/1844/5602/3717/5156/3570/5789/3563/3590/80854/3977/9021/2690/3572/5579/185"
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS",58,-0.513713748037688,-1.37854779911699,0.0652173913043478,0.215062111801242,0.162226217718209,1465,"tags=26%, list=12%, signal=23%","1026/7099/7402/7414/7094/22943/2534/3611/55742/3690/3913/1028/7431/1286/11346"
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling",16,-0.665216071927142,-1.41047674691195,0.0663430420711974,0.216841869827779,0.163568729472978,1244,"tags=31%, list=10%, signal=28%","5906/9252/2908/6722/1958"
"WP1438","Influenza A virus infection",1,-0.961591780151676,-1.28882821931731,0.0665399239543726,0.216841869827779,0.163568729472978,473,"tags=100%, list=4%, signal=96%",""
"WP2267","Synaptic Vesicle Pathway",31,-0.568798832477696,-1.39050776936521,0.0681818181818182,0.219993483484707,0.165946062974403,1703,"tags=29%, list=14%, signal=25%","2055/10497/6812/2054/6571/291/6844/6581/477"
"WP322","Osteoblast Signaling",7,-0.808850305525022,-1.43995220701171,0.0683012259194396,0.219993483484707,0.165946062974403,989,"tags=57%, list=8%, signal=53%","5159/5156/3690/5745"
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma",69,-0.48541180834441,-1.34220701754833,0.0700132100396301,0.224204152381243,0.169122265809146,1778,"tags=26%, list=14%, signal=22%","83439/81029/6423/3725/85407/5176/8061/22943/4609/4920/83595/4919/7482/8324/894/9314/6422/64321"
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway",40,-0.538270309433591,-1.37511668032948,0.0725462304409673,0.230980526806298,0.174233838385142,1891,"tags=35%, list=15%, signal=30%","4791/5970/7188/4792/8737/4790/1432/3725/7185/330/8742/6347/9020/3569"
"WP712","Estrogen signaling pathway",21,-0.61006551356368,-1.37424831464941,0.0740157480314961,0.234312710911136,0.176747380261678,1683,"tags=29%, list=14%, signal=25%","4790/1432/3725/2099/596/2353"
"WP3935","Leptin Insulin Overlap",14,-0.687575875133128,-1.41710045787903,0.0752864157119476,0.236981104002381,0.178760209555282,2110,"tags=64%, list=17%, signal=53%","3643/6774/8503/5170/8660/3717/8835/3953/9021"
"WP197","Cholesterol Biosynthesis Pathway",14,0.62819710570988,1.42438853835171,0.0767263427109974,0.2401491178638,0.181149914102087,1003,"tags=29%, list=8%, signal=26%","1717/4598/6713/2224"
"WP405","Eukaryotic Transcription Initiation",41,0.45874240039583,1.35204407271458,0.0784982935153584,0.244314913525329,0.184292268040197,2669,"tags=37%, list=22%, signal=29%","5437/5436/2960/84172/2968/25885/5439/2071/2967/6883/55703/6877/4331/51728/5438"
"WP2879","Farnesoid X Receptor Pathway",7,-0.789437096627051,-1.40539192706019,0.0805604203152364,0.249332250584586,0.188076958924721,1784,"tags=57%, list=15%, signal=49%","8660/5244/10891/2289"
"WP2637","Structural Pathway of Interleukin 1 (IL-1)",49,-0.509258373676372,-1.32314141379428,0.082036775106082,0.252490963382053,0.190459647468506,3254,"tags=43%, list=27%, signal=32%","1977/7189/5601/5606/5595/4155/23118/10010/5970/9261/54472/4792/4790/1432/5602/9252/4609/4215/1326/9020/2353"
"WP4792","Purine metabolism",11,0.672064316569719,1.4295743423481,0.0831234256926952,0.254421976982062,0.191916254725211,704,"tags=27%, list=6%, signal=26%","3704/1716/3251"
"WP4571","Urea cycle and related diseases",6,0.766274061423484,1.43392081300156,0.084070796460177,0.255907809005154,0.193037051444131,864,"tags=50%, list=7%, signal=47%","10165/162417/10166"
"WP2034","Leptin signaling pathway",75,-0.471684908853682,-1.313839222857,0.0868421052631579,0.261432861432861,0.197204723520513,2636,"tags=31%, list=21%, signal=24%","387/8648/9475/5970/6093/5728/3716/4790/1432/3717/4846/5563/2308/5336/2534/8835/5140/6777/2099/3953/9021/32/1073"
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway",123,-0.431712318811825,-1.2774937379221,0.0872727272727273,0.261432861432861,0.197204723520513,1891,"tags=24%, list=15%, signal=21%","4792/1938/6776/8536/8660/23373/4790/1432/25759/4137/3725/5602/4205/3717/5906/9252/5563/2534/4915/6777/1808/4776/1959/627/32/4804/4208/1958/2353/4684"
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism",66,-0.481297078415223,-1.32003744064085,0.0873015873015873,0.261432861432861,0.197204723520513,1720,"tags=21%, list=14%, signal=18%","23236/1432/9658/2308/63976/10000/3690/9728/7067/2260/6567/10891/4881/11343"
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms",44,-0.518173230910201,-1.34769922939926,0.0878661087866109,0.261708732622486,0.197412819401723,1738,"tags=20%, list=14%, signal=18%","60/7005/5602/7003/3690/58/59/70/72"
"WP1995","Effects of Nitric Oxide",4,-0.848071387134949,-1.37382873500432,0.0895795246800731,0.264516669458871,0.199530909700117,1574,"tags=75%, list=13%, signal=65%","3039/4846/316"
"WP2865","IL1 and megakaryocytes in obesity",21,-0.604117202509258,-1.3608490054608,0.0897637795275591,0.264516669458871,0.199530909700117,1683,"tags=33%, list=14%, signal=29%","4790/7077/114548/1839/2205/6347/8991"
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk",6,-0.796916002083479,-1.37608016613682,0.0909090909090909,0.265071770334928,0.199949634852682,2054,"tags=50%, list=17%, signal=42%","3791/54538/9353"
"WP4666","Hepatitis B infection",130,-0.422343241745898,-1.25151206742508,0.0909090909090909,0.265071770334928,0.199949634852682,2231,"tags=25%, list=18%, signal=20%","842/3339/6778/3716/5578/4773/6776/4790/1432/7098/355/1654/1026/7099/3725/5602/3717/4772/7043/4609/10000/6777/4776/90993/1959/9586/596/2353/7048/5579/1960/3569"
"WP673","ErbB Signaling Pathway",81,-0.4605128471235,-1.29950270167019,0.0920881971465629,0.266130663430421,0.200748381877023,2110,"tags=25%, list=17%, signal=21%","5170/685/5578/6776/25759/1026/3725/5602/2549/374/817/2308/5336/4609/25/10000/6777/1839/5579/9542"
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity",16,-0.645040073787789,-1.36769699846292,0.0922330097087379,0.266130663430421,0.200748381877023,1267,"tags=44%, list=10%, signal=39%","19/10062/5915/5465/5244/5243/5914"
"WP704","Methylation Pathways",7,-0.776780569729948,-1.38286020059103,0.0928196147110333,0.266435577978821,0.200978385820999,1572,"tags=57%, list=13%, signal=50%","3176/4837/4144/11185"
"WP4331","Neovascularisation processes",37,-0.527009536551983,-1.34194147805312,0.0938833570412518,0.268099895880688,0.202233818477357,2594,"tags=49%, list=21%, signal=38%","5601/5595/7040/7042/4791/2324/5970/4855/3791/4254/7852/4790/284/7043/3815/4093/94/6387"
"WP3634","Insulin signalling in human adipocytes (normal condition)",8,-0.751366752993145,-1.39552769939113,0.0949152542372881,0.268280871670702,0.202370332611189,115,"tags=38%, list=1%, signal=37%","3643/6194/6517"
"WP3635","Insulin signalling in human adipocytes (diabetic condition)",8,-0.751366752993145,-1.39552769939113,0.0949152542372881,0.268280871670702,0.202370332611189,115,"tags=38%, list=1%, signal=37%","3643/6194/6517"
"WP357","Fatty Acid Biosynthesis",20,0.5581414734364,1.39298884114133,0.0956284153005464,0.268924579068542,0.202855895668271,281,"tags=15%, list=2%, signal=15%","47/2194/6319"
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment",24,-0.579912872491187,-1.36187345582706,0.0963855421686747,0.269684799805282,0.203429347373545,3325,"tags=54%, list=27%, signal=40%","5133/6774/7189/7040/7042/4791/6778/3566/4790/7099/7043/6347/7048"
"WP129","Matrix Metalloproteinases",22,0.535946775951655,1.3746444569853,0.0980392156862745,0.272093397745572,0.205246207305704,1504,"tags=32%, list=12%, signal=28%","4320/4322/4312/4321/6942/4318/4323"
"WP3967","miR-509-3p alteration of YAP1/ECM axis",17,-0.629257824320371,-1.34893467406777,0.0982286634460548,0.272093397745572,0.205246207305704,1577,"tags=35%, list=13%, signal=31%","7005/5090/10082/7003/10413/1909"
"WP272","Blood Clotting Cascade",12,-0.685631500825806,-1.37300289697842,0.0995024875621891,0.274250637360461,0.206873461964855,1548,"tags=33%, list=13%, signal=29%","2152/7450/2157/2159"
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment",8,-0.747715740054682,-1.38874660391923,0.1,0.274257425742574,0.206878582595102,2399,"tags=50%, list=20%, signal=40%","5970/4792/4790/3569"
"WP2874","Liver X Receptor Pathway",5,0.781145675082165,1.38858579160511,0.10352422907489,0.281933842239186,0.212669077273336,1631,"tags=60%, list=13%, signal=52%","2194/6319/6720"
"WP28","Selenium Metabolism and Selenoproteins",28,-0.554760669368141,-1.33044103553782,0.10381679389313,0.281933842239186,0.212669077273336,1683,"tags=25%, list=14%, signal=22%","4790/4780/3725/8991/1390/2353/2878"
"WP313","Signaling of Hepatocyte Growth Factor Receptor",34,-0.523915545722487,-1.3036221311401,0.10762331838565,0.290845455539757,0.219391308852904,2628,"tags=35%, list=21%, signal=28%","2889/2185/3688/1793/5728/3672/3725/5908/2549/5906/3082/2353"
"WP3972","PDGFR-beta pathway",29,-0.545184974055366,-1.31332318559275,0.108728943338438,0.292250143871091,0.220450897048876,2137,"tags=34%, list=17%, signal=29%","6778/3716/5578/6776/3725/3717/6777/6722/2353/5579"
"WP3940","One carbon metabolism and related pathways",39,-0.512257616041992,-1.30816227173947,0.109530583214794,0.292250143871091,0.220450897048876,760,"tags=13%, list=6%, signal=12%","4524/1036/6649/2878/23743"
"WP53","ID signaling pathway",13,0.611338225699918,1.37488358594489,0.109725685785536,0.292250143871091,0.220450897048876,1631,"tags=38%, list=13%, signal=33%","898/5933/1017/2002/6720"
"WP51","Regulation of Actin Cytoskeleton",117,-0.422153446476017,-1.23738330690987,0.110565110565111,0.293076895947709,0.221074534849403,3203,"tags=39%, list=26%, signal=29%","5293/9564/5595/8503/50649/324/22800/6655/5286/8826/23533/5159/4478/387/7409/9475/10152/6093/1793/22808/1131/3672/2909/7454/10163/60/4659/23396/87/55970/7414/26999/5305/5156/9459/6237/2260/8395/1073/2258/623/2252/624/2934/2247/4638"
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)",20,-0.59950695514597,-1.33813172813509,0.111635220125786,0.293148667924355,0.221128674075563,1433,"tags=25%, list=12%, signal=22%","8989/3248/5465/4056/8309"
"WP3927","BMP Signaling Pathway in Eyelid Development",16,-0.6306524227717,-1.33719044870069,0.111650485436893,0.293148667924355,0.221128674075563,3193,"tags=50%, list=26%, signal=37%","5601/5595/4089/652/3725/5308/3625/6422"
"WP3933","Kennedy pathway from Sphingolipids",12,0.626064103213399,1.37455736891755,0.115288220551378,0.299956542492181,0.22626400792209,2533,"tags=50%, list=21%, signal=40%","9791/5833/10400/8879/10390/55500"
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway",30,-0.535809368717357,-1.30207540671318,0.115326251896813,0.299956542492181,0.22626400792209,3977,"tags=57%, list=32%, signal=38%","5327/7305/868/114609/3551/929/7189/148022/83593/3684/387/23643/4790/7098/7099/6347/3569"
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance",7,-0.75770569431584,-1.34890223733949,0.117338003502627,0.303762868880632,0.229135206052843,1465,"tags=43%, list=12%, signal=38%","1026/5243/55384"
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression",18,0.556284465267421,1.33590851559974,0.119363395225464,0.307568934673987,0.232006207610817,2083,"tags=22%, list=17%, signal=18%","55872/1978/5604/2475"
"WP2333","Trans-sulfuration pathway",10,0.647308682006739,1.35533459222229,0.122249388753056,0.313302917058334,0.236331480281509,1670,"tags=30%, list=14%, signal=26%","1786/191/2730"
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ",12,-0.666981491805223,-1.33565555167254,0.122719734660033,0.313302917058334,0.236331480281509,1891,"tags=50%, list=15%, signal=42%","3551/7189/4792/4790/6237/9020"
"WP4321","Thermogenesis",90,-0.437856245934515,-1.24858410410469,0.124685138539043,0.313370031593615,0.236382106294253,1846,"tags=22%, list=15%, signal=19%","2182/6604/60/1432/9658/108/5563/63976/90993/9586/51422/5592/2260/115/6196/196883/10891/4881/111/11343"
"WP3981","miRNA regulation of prostate cancer signaling pathways",32,-0.523354952521039,-1.28583941456712,0.125188536953243,0.313370031593615,0.236382106294253,2338,"tags=34%, list=19%, signal=28%","5159/23228/842/367/4792/4790/1026/2308/10000/90993/596"
"WP4400","FABP4 in ovarian cancer",1,-0.928565603848977,-1.24456300316878,0.125475285171103,0.313370031593615,0.236382106294253,878,"tags=100%, list=7%, signal=93%",""
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology",41,-0.498323455240057,-1.28356503808783,0.125528913963329,0.313370031593615,0.236382106294253,1723,"tags=22%, list=14%, signal=19%","2010/3799/108/7043/115/196883/23345/6722/111"
"WP2870","Extracellular vesicle-mediated signaling in recipient cells",27,-0.547646696992832,-1.30675592947198,0.125574272588055,0.313370031593615,0.236382106294253,3164,"tags=41%, list=26%, signal=30%","7103/324/7040/23533/4089/7042/4240/7043/3082/7049/7048"
"WP4155","Endometrial cancer",59,-0.474433113541208,-1.269837304034,0.129427792915531,0.321538104373114,0.242543468432693,2414,"tags=37%, list=20%, signal=30%","5293/2309/5595/8503/324/6655/8313/842/5728/5170/1647/51426/83439/10912/1026/4609/3611/10000/4616/2260/2247/2353"
"WP4545","Oxysterols derived from cholesterol",10,-0.689027938108387,-1.33384495316058,0.133220910623946,0.329221999878722,0.248339604696661,903,"tags=80%, list=7%, signal=74%","53342/9420/7376/1593/2099/9023/2053/1880"
"WP195","IL-1 signaling pathway",55,-0.47719026359511,-1.2699676196789,0.133977900552486,0.329221999878722,0.248339604696661,2399,"tags=24%, list=20%, signal=19%","5970/9261/54472/4792/4790/1432/3725/4215/57161/11213/6347/9020/3316"
"WP2436","Dopamine metabolism",9,-0.702346905291786,-1.33818347766561,0.136134453781513,0.329221999878722,0.248339604696661,726,"tags=67%, list=6%, signal=63%","4128/5566/5515/5567/5516/4129"
"WP117","GPCRs, Other",22,-0.573012284766239,-1.31124406267236,0.136434108527132,0.329221999878722,0.248339604696661,2136,"tags=41%, list=17%, signal=34%","1131/27239/3579/59352/154/1909/1880/1901/5737"
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)",41,0.436915078207973,1.28771275831709,0.136518771331058,0.329221999878722,0.248339604696661,2459,"tags=37%, list=20%, signal=29%","2194/6319/1717/10682/4598/6713/1718/2224/3992/6720/51478/7108/6646/4597/9415"
"WP4507","Molybdenum cofactor (Moco) biosynthesis",7,-0.746174812851297,-1.32837443621208,0.136602451838879,0.329221999878722,0.248339604696661,62,"tags=43%, list=1%, signal=43%","54996/4338/316"
"WP560","TGF-beta Receptor Signaling",46,-0.485805165126977,-1.26333149329637,0.136680613668061,0.329221999878722,0.248339604696661,2795,"tags=48%, list=23%, signal=37%","4091/25805/4089/7030/10468/864/4052/2022/3716/652/6497/7057/4790/3725/3976/23090/4092/4093/9839/7049/2353/7048"
"WP500","Glycogen Synthesis and Degradation",36,-0.500746250862426,-1.26823953268594,0.137733142037303,0.330321041942276,0.249168636996169,2727,"tags=42%, list=22%, signal=32%","805/3098/5236/5527/808/801/2632/7360/5834/5257/2992/5521/5516/5525/5837"
"WP4329","miRNAs involvement in the immune response in sepsis",32,-0.515204687738098,-1.2658148945992,0.14027149321267,0.333291843000581,0.251409579462722,2828,"tags=31%, list=23%, signal=24%","23118/4791/6351/5970/4792/4790/1432/7412/7099/3569"
"WP3945","TYROBP Causal Network",57,-0.470607876805127,-1.25984734373655,0.140518417462483,0.333291843000581,0.251409579462722,2514,"tags=39%, list=20%, signal=31%","3684/864/4066/920/678/10019/10257/3142/113277/4094/64092/5341/6776/6039/3587/1806/951/54518/7133/5996/3071/718"
"WP4494","Selective expression of chemokine receptors during T-cell polarization",16,-0.61627781430795,-1.30671155343687,0.140776699029126,0.333291843000581,0.251409579462722,2929,"tags=50%, list=24%, signal=38%","7040/7042/6351/920/3566/940/7852/7043"
"WP3963","Mevalonate pathway",7,0.69055105403028,1.33106894039181,0.1415313225058,0.333652564545589,0.251681679887135,1003,"tags=43%, list=8%, signal=39%","4598/39/2224"
"WP4583","Biomarkers for urea cycle disorders",8,-0.720401424353174,-1.33801520810018,0.144067796610169,0.33819304797472,0.25510666928741,992,"tags=25%, list=8%, signal=23%","2593/2159"
"WP2290","RalA downstream regulated genes",11,0.616984343503787,1.31241157335274,0.148614609571788,0.343953394521994,0.259451829042811,917,"tags=18%, list=7%, signal=17%","5881/4893"
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma",11,0.618066957558873,1.31471444413112,0.148614609571788,0.343953394521994,0.259451829042811,1153,"tags=27%, list=9%, signal=25%","84759/2146/23512"
"WP3407","FTO Obesity Variant Mechanism",7,-0.737141817031022,-1.31229348504166,0.148861646234676,0.343953394521994,0.259451829042811,1086,"tags=57%, list=9%, signal=52%","79068/84159/63976/10891"
"WP176","Folate Metabolism",44,-0.480683832405608,-1.25019432088337,0.149232914923291,0.343953394521994,0.259451829042811,1854,"tags=30%, list=15%, signal=25%","3043/6648/4790/1435/3039/3949/4524/6347/2350/12/6649/2878/3569"
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing",13,0.583090004904789,1.31135408055709,0.149625935162095,0.343953394521994,0.259451829042811,2232,"tags=31%, list=18%, signal=25%","10535/103/3661/4938"
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling",15,-0.617996348281414,-1.29164224868534,0.151067323481117,0.345831806646854,0.260868757816456,236,"tags=20%, list=2%, signal=20%","9261/6722/3708"
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling",21,-0.570189895481792,-1.28442353398851,0.152755905511811,0.348258319561907,0.262699131419489,2384,"tags=38%, list=19%, signal=31%","2052/10257/9429/1432/4780/3725/1066/2353"
"WP4565","Neural Crest Cell Migration in Cancer",36,-0.487978917708635,-1.23590372067592,0.156384505021521,0.355069736811158,0.267837137590784,1374,"tags=17%, list=11%, signal=15%","3725/10000/4915/627/4804/2353"
"WP4399","MicroRNA network associated with chronic lymphocytic leukemia",4,-0.806567575085458,-1.30659485532063,0.157221206581353,0.355512442637018,0.268171080613521,1350,"tags=75%, list=11%, signal=67%","7535/4170/596"
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness",13,-0.639079564832203,-1.29813292391979,0.15973377703827,0.359725660484558,0.271349206179688,1374,"tags=31%, list=11%, signal=27%","3725/3690/8076/6263"
"WP4478","LTF danger signal response pathway",14,-0.630241241967544,-1.29893323030499,0.160392798690671,0.359747410828469,0.271365612956303,1683,"tags=21%, list=14%, signal=19%","4790/7099/3569"
"WP4657","22q11.2 Deletion Syndrome",58,-0.459139688763816,-1.2320986344056,0.161684782608696,0.360412238325282,0.271867107381982,1672,"tags=21%, list=14%, signal=18%","8854/8036/4942/5308/7450/2260/9464/59/6722/70/6517/7122"
"WP3617","Photodynamic therapy-induced NF-kB survival signaling",30,-0.514681128728561,-1.25073147119671,0.16236722306525,0.360412238325282,0.271867107381982,1683,"tags=30%, list=14%, signal=26%","4790/7412/8837/5743/599/6401/330/2920/3569"
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway",17,-0.597488701604883,-1.28083147448989,0.162640901771337,0.360412238325282,0.271867107381982,1638,"tags=35%, list=13%, signal=31%","4780/308/3490/5310/23411/2252"
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ",16,0.549418779946081,1.28516286543976,0.1640625,0.361713241055106,0.272848483182362,1153,"tags=25%, list=9%, signal=23%","2146/5928/22823/23512"
"WP4720","Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway",4,-0.804835250156437,-1.30378858476139,0.164533820840951,0.361713241055106,0.272848483182362,1267,"tags=75%, list=10%, signal=67%","66002/5465/2053"
"WP4225","Pyrimidine metabolism and related diseases",12,0.580709706759817,1.27497935519964,0.165413533834586,0.362209872507355,0.273223103525404,1862,"tags=42%, list=15%, signal=35%","6241/790/7298/1890/7372"
"WP2542","Sulindac Metabolic Pathway",4,-0.802265749614226,-1.29962613601822,0.16819012797075,0.366790254237288,0.27667818911686,1610,"tags=100%, list=13%, signal=87%","22921/4482/253827"
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)",25,-0.539379175210211,-1.27220954710782,0.169184290030211,0.366790254237288,0.27667818911686,1261,"tags=24%, list=10%, signal=22%","3717/4609/2908/2099/857/5241"
"WP1455","Serotonin Transporter Activity",8,-0.706628333403954,-1.31243418545138,0.169491525423729,0.366790254237288,0.27667818911686,949,"tags=38%, list=8%, signal=35%","3690/5516/7041"
"WP3851","TLR4 Signaling and Tolerance",25,-0.536910168476245,-1.26638601130371,0.170694864048338,0.367957022111982,0.277558308528324,1891,"tags=36%, list=15%, signal=31%","148022/3635/23118/4792/8737/4790/7099/11213/3569"
"WP1603","Nicotine Activity on Chromaffin Cells",1,-0.908423713610046,-1.21756668615967,0.173003802281369,0.370772619451034,0.279682177317234,1125,"tags=100%, list=9%, signal=91%",""
"WP1545","miRNAs involved in DNA damage response",14,0.568979686181884,1.29011760192145,0.173913043478261,0.370772619451034,0.279682177317234,287,"tags=21%, list=2%, signal=21%","898/993/1869"
"WP2805","exRNA mechanism of action and biogenesis",5,0.728782551156112,1.29550367874552,0.174008810572687,0.370772619451034,0.279682177317234,2558,"tags=40%, list=21%, signal=32%","57510/29102"
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions",31,-0.503616815115451,-1.23116127216815,0.175757575757576,0.373063973063973,0.281410597200071,2932,"tags=45%, list=24%, signal=34%","2309/83706/83593/4023/387/3683/4303/1432/7005/5906/2308/7003/10413/26524"
"WP1423","Ganglio Sphingolipid Metabolism",8,-0.703892259759247,-1.3073524240565,0.177966101694915,0.376310001293828,0.283859149750427,343,"tags=75%, list=3%, signal=73%","8869/6483/8705/6482/6489/30815"
"WP4342","Vitamins A and D - action mechanisms",3,-0.829052162666763,-1.27659659137119,0.178846153846154,0.376732962854636,0.284178199227229,606,"tags=67%, list=5%, signal=63%","6256/5914"
"WP364","IL-6 signaling pathway",41,-0.470650088907796,-1.21228489837782,0.180535966149506,0.378851989571313,0.285776629032512,1324,"tags=17%, list=11%, signal=15%","2549/3717/3570/3726/9021/3572/3569"
"WP3996","Ethanol effects on histone modifications",28,-0.512185591196412,-1.22833640877072,0.184732824427481,0.386196168803111,0.291316509623475,962,"tags=32%, list=8%, signal=30%","8854/216/8850/126/4524/9759/10014/217/125"
"WP58","Monoamine GPCRs",5,-0.76765070158419,-1.29547918412329,0.186131386861314,0.387657098951759,0.292418522294981,2136,"tags=100%, list=17%, signal=83%","1131/152/154/150"
"WP2645","Heroin metabolism",2,-0.86609036046322,-1.24571481649357,0.196819085487078,0.406563924880596,0.306680368948502,1645,"tags=100%, list=13%, signal=87%","1066"
"WP2826","Cocaine metabolism",2,-0.86609036046322,-1.24571481649357,0.196819085487078,0.406563924880596,0.306680368948502,1645,"tags=100%, list=13%, signal=87%","1066"
"WP100","Glutathione metabolism",16,-0.586666158496733,-1.24392510896885,0.197411003236246,0.406563924880596,0.306680368948502,70,"tags=12%, list=1%, signal=12%","2678/2878"
"WP550","Biogenic Amine Synthesis",3,0.806213880187264,1.24234199325272,0.201244813278008,0.412924542800061,0.311478326983896,621,"tags=33%, list=5%, signal=32%","2571"
"WP3584","MECP2 and Associated Rett Syndrome",51,-0.45231991745164,-1.18782464349592,0.205020920502092,0.417579374846173,0.314989572133632,1651,"tags=25%, list=13%, signal=22%","50937/6446/26084/4354/4204/2593/1052/3479/627/1465/2289/4208/2247"
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.",46,-0.455768929026883,-1.18522256047879,0.205020920502092,0.417579374846173,0.314989572133632,1674,"tags=30%, list=14%, signal=26%","1432/4780/8837/355/1026/3725/4170/5156/3726/1839/596/2252/2353/3569"
"WP4259","Disorders of Folate Metabolism and Transport",11,0.581928542297901,1.23784300496009,0.206549118387909,0.419133045236107,0.316161540867821,961,"tags=36%, list=8%, signal=34%","6472/7298/2618/4522"
"WP47","Hedgehog Signaling Pathway Netpath",12,-0.619709676284936,-1.24099196113358,0.207296849087894,0.419133045236107,0.316161540867821,3357,"tags=92%, list=27%, signal=67%","25942/406/2737/6608/10284/51684/2736/374654/5727/2735/8643"
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway",52,-0.448218619434276,-1.18190139061762,0.2125,0.428042203506043,0.322881920562225,3220,"tags=38%, list=26%, signal=28%","7189/9060/5601/5595/1513/23118/2274/4791/5970/7188/4792/4790/1432/7412/9846/3725/7185/4772/4286/2353"
"WP4629","Computational Model of Aerobic Glycolysis",11,0.570209984314,1.21291600108551,0.214105793450882,0.428042203506043,0.322881920562225,2109,"tags=45%, list=17%, signal=38%","2023/7167/5230/2597/2821"
"WP127","IL-5 Signaling Pathway",38,-0.465083592089403,-1.18175225508272,0.214285714285714,0.428042203506043,0.322881920562225,1402,"tags=26%, list=11%, signal=23%","3716/6776/4137/3725/3717/695/4609/6777/596/2353"
"WP2526","PDGF Pathway",39,-0.46291059179232,-1.18214381281481,0.214793741109531,0.428042203506043,0.322881920562225,2732,"tags=26%, list=22%, signal=20%","5321/5159/387/7409/3716/4792/4790/3725/6722/2353"
"WP4312","Rett syndrome causing genes",37,-0.459999509699044,-1.17131167300681,0.217638691322902,0.430884755701784,0.325026122009516,1768,"tags=30%, list=14%, signal=26%","6595/8831/85358/6907/6594/4204/6812/6925/2775/10014/4208"
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma",13,-0.609637031164943,-1.23832765956726,0.217970049916805,0.430884755701784,0.325026122009516,1683,"tags=69%, list=14%, signal=60%","5970/3716/4790/3717/3570/3590/6935/3572/3569"
"WP262","EBV LMP1 signaling",20,-0.549861542676863,-1.22732050065718,0.218553459119497,0.430884755701784,0.325026122009516,2568,"tags=40%, list=21%, signal=32%","4791/5970/4792/4790/7185/9260/4215/9020"
"WP4724","Omega-9 FA synthesis",12,0.553768985102902,1.21582955362596,0.220551378446115,0.433096719722318,0.32669465652624,1248,"tags=25%, list=10%, signal=22%","2194/6319/3992"
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ",6,0.666337498044347,1.24691054419122,0.221238938053097,0.433096719722318,0.32669465652624,768,"tags=33%, list=6%, signal=31%","51804/5725"
"WP136","Phase I biotransformations, non P450",5,-0.739821662940272,-1.24851519359614,0.224452554744526,0.437840546931222,0.330273032741203,1645,"tags=60%, list=13%, signal=52%","8824/2098/1066"
"WP4760","PKC-gamma calcium signaling pathway in ataxia",12,-0.605157079423319,-1.21184983795882,0.225538971807629,0.438416106601495,0.330707190425221,1720,"tags=50%, list=14%, signal=43%","23236/2767/9630/5332/6263/3708"
"WP2113","Type III interferon signaling",6,0.664747957066106,1.2439360524179,0.22787610619469,0.441410359551952,0.332965823184733,2081,"tags=67%, list=17%, signal=55%","7297/6773/10379/6772"
"WP3640","Imatinib and Chronic Myeloid Leukemia",20,-0.544154327300876,-1.21458168935841,0.229559748427673,0.443122301842965,0.334257179995548,2687,"tags=60%, list=22%, signal=47%","5159/4066/5292/1647/9429/1436/9846/4609/25/5156/3815/5243"
"WP395","IL-4 Signaling Pathway",53,-0.439487791416093,-1.16371689376347,0.230769230769231,0.443910256410256,0.334851551956815,2150,"tags=47%, list=18%, signal=39%","6774/5293/3269/1051/5595/3635/9655/5970/9046/6778/3716/4792/3566/6776/8660/4790/1432/9846/2242/4783/3717/6777/9021/2316/2353"
"WP2846","Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation",1,-0.875071352850037,-1.17286428269115,0.23384030418251,0.446715615576242,0.336967697860095,1534,"tags=100%, list=13%, signal=87%",""
"WP3408","Evolocumab Mechanism",1,-0.875071352850037,-1.17286428269115,0.23384030418251,0.446715615576242,0.336967697860095,1534,"tags=100%, list=13%, signal=87%",""
"WP4484","Control of immune tolerance by vasoactive intestinal peptide",4,-0.761386568477861,-1.23340412386154,0.235831809872029,0.448971899206544,0.338669663661406,2929,"tags=75%, list=24%, signal=57%","7040/940/355"
"WP399","Wnt Signaling Pathway and Pluripotency",86,-0.400753272428136,-1.13936583032022,0.236775818639798,0.449225354542631,0.33886085075703,1778,"tags=23%, list=14%, signal=20%","960/5578/83439/81029/3949/5587/3725/5602/85407/8061/5048/4609/8322/5521/5516/7482/8324/894/120892/5579"
"WP3944","Serotonin and anxiety-related events",6,-0.718857337788404,-1.24129183279836,0.238181818181818,0.449734321700341,0.339244776201853,435,"tags=67%, list=4%, signal=64%","5341/84812/2353/5579"
"WP134","Pentose Phosphate Metabolism",7,0.633352370074243,1.22081584440301,0.238979118329466,0.449734321700341,0.339244776201853,4501,"tags=100%, list=37%, signal=63%","22934/5226/6120/7086/2539/6888/25796"
"WP2037","Prolactin Signaling Pathway",73,-0.413043871266113,-1.14586067120391,0.239735099337748,0.449734321700341,0.339244776201853,1891,"tags=26%, list=15%, signal=22%","5970/3688/3716/4792/6776/8660/4790/1432/9846/3725/3717/4609/2534/8835/6777/9021/6196/2316/2353"
"WP2007","Iron metabolism in placenta",8,0.616110639410739,1.22324675984462,0.240291262135922,0.449734321700341,0.339244776201853,2934,"tags=62%, list=24%, signal=48%","7037/55240/4891/3658/57192"
"WP3585","Cytosine methylation",8,0.612319276791936,1.21571926114198,0.242718446601942,0.450611371237458,0.33990635451505,1135,"tags=38%, list=9%, signal=34%","1786/6996/200424"
"WP12","Osteoclast Signaling",12,0.54090801631812,1.18759260580576,0.243107769423559,0.450611371237458,0.33990635451505,1097,"tags=17%, list=9%, signal=15%","6696/7965"
"WP78","TCA Cycle (aka Krebs or citric acid cycle)",18,-0.546966546511219,-1.18737906735926,0.2432,0.450611371237458,0.33990635451505,2454,"tags=50%, list=20%, signal=40%","3421/3419/8803/8801/1743/8802/4967/50/6392"
"WP437","EGF/EGFR Signaling Pathway",155,-0.368829675291429,-1.1140011992856,0.247072599531616,0.456260733801717,0.344167796540532,1374,"tags=22%, list=11%, signal=20%","2887/6093/5900/4303/5728/9046/3716/5170/5578/6776/1432/9846/3725/2549/4205/54206/3717/5906/9252/4846/6812/2308/25/10253/4215/6777/6196/857/4208/2353/4209/3727/5579/2354"
"WP2873","Aryl Hydrocarbon Receptor Pathway",31,-0.472697486596291,-1.15557467797251,0.251515151515152,0.462921574549482,0.349192219449257,3009,"tags=39%, list=25%, signal=29%","26509/57491/405/7040/1545/8648/51426/4780/3725/3726/10486/3727"
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection",50,-0.436863724954575,-1.14531286777697,0.254545454545455,0.465493793473836,0.351132502392386,3325,"tags=44%, list=27%, signal=32%","5133/27040/5601/5595/915/805/3937/8915/920/801/5788/4773/4792/940/3702/4790/3725/2534/6237/1326/9020/2353"
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer",76,-0.403556638271017,-1.12629855245576,0.254593175853018,0.465493793473836,0.351132502392386,1778,"tags=22%, list=14%, signal=19%","83439/81029/6423/3725/85407/5176/8061/22943/4609/4920/4919/7482/8324/894/467/6422/64321"
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1",9,-0.635976954792988,-1.21172862963851,0.25546218487395,0.465546218487395,0.351172047766475,2156,"tags=44%, list=18%, signal=37%","4097/4780/7975/23764"
"WP4564","Neural Crest Cell Migration during Development",33,-0.462906758999675,-1.14280373203889,0.26015037593985,0.472535436953038,0.356444173418879,1374,"tags=15%, list=11%, signal=13%","3725/10000/627/4804/2353"
"WP4298","Viral Acute Myocarditis",70,-0.405931686802972,-1.12412875804647,0.262187088274045,0.473966086614308,0.357523344833518,2374,"tags=30%, list=19%, signal=24%","3108/920/842/199/3716/1604/7100/7852/60/7098/7099/6443/25/2534/6444/1756/596/3908/857/6442/3569"
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase",5,-0.720037570268548,-1.21512776858618,0.262773722627737,0.473966086614308,0.357523344833518,446,"tags=40%, list=4%, signal=39%","2950/2053"
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)",70,-0.404845153425867,-1.121119868976,0.263504611330698,0.473966086614308,0.357523344833518,1894,"tags=17%, list=15%, signal=15%","293/4698/7386/4714/6392/7385/1350/4724/9481/291/7381/1346"
"WP4698","Vitamin D-sensitive calcium signaling in depression",22,-0.5134032330874,-1.17483858381374,0.268217054263566,0.480881061689371,0.362739467016303,1638,"tags=36%, list=13%, signal=32%","4780/23135/775/6546/1593/493/596/3708"
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3",58,-0.419427205786148,-1.12553042163058,0.275815217391304,0.491333243522385,0.370623784302464,1720,"tags=21%, list=14%, signal=18%","23236/4790/1432/7099/3725/817/5336/5332/6347/857/5579/3569"
"WP2359","Parkin-Ubiquitin Proteasomal System pathway",59,0.345330038640725,1.09883296877405,0.276119402985075,0.491333243522385,0.370623784302464,2038,"tags=27%, list=17%, signal=23%","898/5709/10381/5717/10213/8573/5708/3309/203068/5714/51182/5718/5706/5704/118424/5710"
"WP4519","Cerebral Organic Acidurias, including diseases",7,-0.671021944493466,-1.19458387210409,0.276707530647986,0.491333243522385,0.370623784302464,1075,"tags=29%, list=9%, signal=26%","501/137872"
"WP43","Oxidation by Cytochrome P450",30,-0.471308323853424,-1.14533080848849,0.277693474962064,0.491508578686848,0.370756043584797,2669,"tags=30%, list=22%, signal=24%","1545/9420/1577/285440/113612/57404/1727/1593/51302"
"WP3942","PPAR signaling pathway",45,-0.429432073950281,-1.11812808518975,0.280945757997218,0.494543732123663,0.373045528506734,2302,"tags=33%, list=19%, signal=27%","6257/376497/5170/51129/23205/5360/948/2182/5465/34/3611/1593/2167/10580/8309"
"WP4241","Type 2 papillary renal cell carcinoma",30,-0.469776493910697,-1.14160829407918,0.282245827010622,0.494543732123663,0.373045528506734,3443,"tags=47%, list=28%, signal=34%","112398/1387/54583/1513/405/7040/7030/7042/2034/9915/1026/7043/81578/7942"
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling",29,-0.470189982703728,-1.13266402286346,0.284839203675345,0.494543732123663,0.373045528506734,2266,"tags=31%, list=18%, signal=25%","3688/5728/4790/84557/3488/114907/3611/3479/10891"
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)",15,0.498153280104064,1.14693137568047,0.28498727735369,0.494543732123663,0.373045528506734,49,"tags=7%, list=0%, signal=7%","47"
"WP496","Steroid Biosynthesis",4,0.72097485115291,1.20799571376043,0.285087719298246,0.494543732123663,0.373045528506734,1869,"tags=50%, list=15%, signal=42%","3292/51478"
"WP2456","HIF1A and PPARG regulation of glycolysis",6,0.638358622940121,1.19455396140178,0.285398230088496,0.494543732123663,0.373045528506734,4439,"tags=100%, list=36%, signal=64%","7167/2597/5468/3939/6513/3091"
"WP3982","miRNA regulation of p53 pathway in prostate cancer",23,0.438123833386753,1.12980029409198,0.286127167630058,0.494543732123663,0.373045528506734,2274,"tags=30%, list=19%, signal=25%","637/11200/317/581/27113/64065/836"
"WP2371","Parkinsons Disease Pathway",31,0.407580501350653,1.13752261141839,0.286549707602339,0.494543732123663,0.373045528506734,117,"tags=10%, list=1%, signal=10%","835/898/9134"
"WP2112","IL17 signaling pathway",27,-0.473056074409006,-1.12877304583615,0.287901990811639,0.495334481085863,0.373642008343317,3262,"tags=48%, list=27%, signal=35%","6774/7189/1051/5595/53342/54756/5970/3716/4790/84818/3717/1052/9020"
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer",15,-0.558397018660697,-1.16707676808741,0.288998357963875,0.495681394154758,0.373903692721716,891,"tags=47%, list=7%, signal=43%","9648/79083/94121/83874/94120/5873/25924"
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia",21,-0.512853220289112,-1.15526555423177,0.292913385826772,0.499673517322372,0.376915041567512,1121,"tags=24%, list=9%, signal=22%","22943/4609/862/5914/7704"
"WP4561","Cell migration and invasion through p75NTR",28,-0.469638460619927,-1.12629880663174,0.293129770992366,0.499673517322372,0.376915041567512,1374,"tags=18%, list=11%, signal=16%","3725/10000/4915/627/4804"
"WP3853","ERK Pathway in Huntington's Disease",13,-0.570317404688672,-1.15845951091432,0.29450915141431,0.500484876943336,0.377527068490413,1214,"tags=23%, list=10%, signal=21%","9252/4915/627"
"WP1559","TFs Regulate miRNAs related to cardiac hypertrophy",7,-0.65748108846836,-1.17047782258542,0.297723292469352,0.504399706507709,0.380480113022156,3262,"tags=71%, list=27%, signal=52%","208/6774/7040/50804/4790"
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation",10,-0.599135808621072,-1.15982855032112,0.300168634064081,0.506992144120429,0.382435647379461,3114,"tags=80%, list=25%, signal=60%","4086/10140/659/4091/4089/650/657/10766"
"WP3941","Oxidative Damage",37,-0.43402300547821,-1.10516685768368,0.307254623044097,0.517383164639604,0.390273829302532,2532,"tags=38%, list=21%, signal=30%","712/728/842/727/1647/4790/1026/5602/7185/7133/716/1028/715/596"
"WP3596","miR-517 relationship with ARCN1 and USP1",5,-0.701676650941553,-1.18414207582201,0.308394160583942,0.517728378677284,0.390534232063237,1465,"tags=60%, list=12%, signal=53%","3397/1026/3398"
"WP4146","Macrophage markers",9,-0.604332282740576,-1.15143594951473,0.315966386554622,0.527907995618839,0.398212947483715,4008,"tags=78%, list=33%, signal=52%","9308/968/9332/5880/929/972/2152"
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging",6,-0.671287283821893,-1.15914991621715,0.316363636363636,0.527907995618839,0.398212947483715,2187,"tags=50%, list=18%, signal=41%","5728/2308/23411"
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells",17,-0.522347184555542,-1.119751240137,0.334943639291465,0.555607802799309,0.419107538877685,1486,"tags=53%, list=12%, signal=47%","5728/3791/2114/7099/3479/10611/975/8470/3569"
"WP2857","Mesodermal Commitment Pathway",116,-0.366763454577847,-1.07371031092087,0.334969325153374,0.555607802799309,0.419107538877685,2852,"tags=34%, list=23%, signal=27%","23499/4091/203228/4089/655/6001/58499/1488/6615/79776/8313/55809/23576/5573/1466/28514/652/5087/8646/83439/23373/657/4780/5090/5308/3717/57198/22943/84159/7003/4211/9760/6925/8322/10413/2260/2627/6722/9314/64321"
"WP3613","Photodynamic therapy-induced unfolded protein response",24,0.420857258987172,1.08874893331142,0.337278106508876,0.557767376137066,0.420736553916807,1927,"tags=33%, list=16%, signal=28%","10130/7184/811/51726/57761/3309/27113/10018"
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses",8,-0.608349536372598,-1.12989911456391,0.340677966101695,0.56133748281103,0.423429566171345,3938,"tags=88%, list=32%, signal=59%","1385/4548/1051/128/10840/216/4524"
"WP1449","Regulation of toll-like receptor signaling pathway",111,-0.365542960124691,-1.06682625453481,0.341463414634146,0.56133748281103,0.423429566171345,3277,"tags=36%, list=27%, signal=27%","929/7189/5293/5601/5606/5595/8503/54461/148022/23533/7096/23118/4091/79004/4791/23098/6351/5970/54472/23643/4792/7100/1540/8737/7128/4790/1432/7098/7099/3725/5602/10771/695/8727/10000/57161/11213/1326/2353/3569"
"WP453","Inflammatory Response Pathway",22,-0.482494814890021,-1.10410976887317,0.342635658914729,0.56159809183065,0.423626149452343,3595,"tags=55%, list=29%, signal=39%","3932/7132/3561/958/7535/7059/3915/3566/940/7057/7133/3913"
"WP4524","The alternative pathway of fetal androgen synthesis",4,-0.712111533454146,-1.15358129283475,0.343692870201097,0.561669174310937,0.423679768575797,433,"tags=50%, list=4%, signal=48%","1528/8630"
"WP4197","The human immune response to tuberculosis",23,0.417643777463188,1.07698788937389,0.346820809248555,0.56511390683441,0.426278208271444,3876,"tags=57%, list=32%, signal=39%","7297/6773/10379/3437/6772/4938/6890/4599/5771/3460/9282/5696/3455"
"WP384","Apoptosis Modulation by HSP70",18,0.450898582228663,1.08282595197324,0.350132625994695,0.568837169504578,0.42908674955979,1263,"tags=22%, list=10%, signal=20%","835/637/317/839"
"WP615","Senescence and Autophagy in Cancer",93,-0.370743755112995,-1.06290825775089,0.353673723536737,0.572910066781732,0.432159028144305,1745,"tags=17%, list=14%, signal=15%","7057/1432/3490/9547/1026/3725/84557/3488/3570/81631/3479/596/23710/3572/2934/3569"
"WP363","Wnt Signaling Pathway (Netpath)",48,-0.410718904977567,-1.06736380224482,0.356241234221599,0.575386716497859,0.434027221070967,1064,"tags=27%, list=9%, signal=25%","1452/387/7249/8313/5578/4773/7010/4609/4920/6925/4919/8395/5579"
"WP2876","Pregnane X Receptor pathway",18,-0.504420778584322,-1.09501884064458,0.36,0.579767441860465,0.437331701346389,2634,"tags=33%, list=21%, signal=26%","8648/1577/10257/2308/5243/10891"
"WP4224","Purine metabolism and related disorders",19,0.440061045999739,1.06819526275565,0.363387978142077,0.581840866736157,0.438895732651063,743,"tags=32%, list=6%, signal=30%","10606/3704/1716/3251/5471/2618"
"WP4288","MTHFR deficiency",19,0.441564506115428,1.07184473136442,0.363387978142077,0.581840866736157,0.438895732651063,841,"tags=21%, list=7%, signal=20%","2906/1786/1789/1788"
"WP4483","Relationship between inflammation, COX-2 and EGFR",22,-0.464475347238321,-1.06287519048983,0.368992248062016,0.588205839125012,0.443696975361258,1407,"tags=36%, list=11%, signal=32%","5293/5595/51365/5743/5734/10000/2099/5733"
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway",22,-0.463523354991416,-1.06069671331814,0.370542635658915,0.588205839125012,0.443696975361258,3131,"tags=41%, list=26%, signal=31%","5595/6194/7249/5578/1432/6446/374/2308/627"
"WP4758","Nephrotic syndrome",33,-0.43316234442618,-1.06937203694902,0.371428571428571,0.588205839125012,0.443696975361258,911,"tags=15%, list=7%, signal=14%","4000/3913/83478/1286/11346"
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases",5,0.639653233439367,1.13706498012006,0.372246696035242,0.588205839125012,0.443696975361258,2267,"tags=60%, list=18%, signal=49%","79017/26873/2937"
"WP3302","eIF5A regulation in response to inhibition of the nuclear export system",3,0.72428600979135,1.11609455902724,0.37344398340249,0.588205839125012,0.443696975361258,2742,"tags=67%, list=22%, signal=52%","7514/1984"
"WP4722","Glycerolipids and Glycerophospholipids",18,0.443478108165871,1.06500579859991,0.374005305039788,0.588205839125012,0.443696975361258,3552,"tags=50%, list=29%, signal=36%","9791/5833/10400/54675/55500/1040/84649/8694/57678"
"WP1584","Type II diabetes mellitus",14,-0.529166050854214,-1.09061629425894,0.374795417348609,0.588205839125012,0.443696975361258,115,"tags=50%, list=1%, signal=50%","3667/5594/6834/3551/3643/23533/6517"
"WP2289","Drug Induction of Bile Acid Pathway",4,-0.694765368114686,-1.12548146451017,0.380255941499086,0.592278244631186,0.446768882991793,2260,"tags=50%, list=18%, signal=41%","10257/5243"
"WP143","Fatty Acid Beta Oxidation",27,-0.447716674075732,-1.06830995564207,0.382848392036753,0.592278244631186,0.446768882991793,3411,"tags=48%, list=28%, signal=35%","3032/1632/57104/788/4023/1374/3033/3991/3030/1384/2182/34/38"
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition",17,-0.50186640453637,-1.07584676529054,0.384863123993559,0.592278244631186,0.446768882991793,4229,"tags=59%, list=34%, signal=39%","5594/3397/4087/3371/5595/7040/4089/6615/1004/7431"
"WP727","Monoamine Transport",17,-0.501799752624678,-1.07570388415136,0.384863123993559,0.592278244631186,0.446768882991793,1949,"tags=53%, list=16%, signal=45%","273/183/1432/60482/10497/114907/3690/5516/7041"
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders",9,-0.578300887098258,-1.10183826027219,0.384873949579832,0.592278244631186,0.446768882991793,248,"tags=44%, list=2%, signal=44%","27430/635/4548/1036"
"WP4479","Supression of HMGB1 mediated inflammation by THBD",9,-0.578147662384566,-1.10154632080654,0.384873949579832,0.592278244631186,0.446768882991793,2399,"tags=67%, list=20%, signal=54%","7056/8517/3551/5970/4792/4790"
"WP698","Glucuronidation",9,-0.577466156342071,-1.1002478454817,0.384873949579832,0.592278244631186,0.446768882991793,71,"tags=44%, list=1%, signal=44%","3098/5236/7360/5239"
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ",11,-0.557059455234525,-1.10026107435266,0.386776859504132,0.593557839793045,0.447734110579211,48,"tags=27%, list=0%, signal=27%","3716/3587/3569"
"WP3971","Role of Osx and miRNAs in tooth development",10,-0.564283191145476,-1.09235960551768,0.387858347386172,0.593573271966683,0.447745751417012,3191,"tags=50%, list=26%, signal=37%","4853/655/4855/22943/9314"
"WP3529","Zinc homeostasis",24,0.402638749574989,1.04161803021906,0.390532544378698,0.596019365250135,0.449590894935024,1824,"tags=38%, list=15%, signal=32%","55630/55676/201266/7922/29985/148867/27173/57181/55334"
"WP690","Polyol Pathway",3,0.714075842567785,1.10036111680838,0.392116182572614,0.59679221193744,0.450173870680532,2353,"tags=67%, list=19%, signal=54%","231/6652"
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways",55,-0.389979357081053,-1.03786936494655,0.393646408839779,0.597479754786952,0.450692499810792,1825,"tags=16%, list=15%, signal=14%","6776/8536/1026/3725/4609/8322/58/8324/4638"
"WP3925","Amino Acid metabolism",66,-0.383941301514217,-1.05302299917537,0.395502645502646,0.59811834867102,0.451174205628719,2417,"tags=26%, list=20%, signal=21%","384/2746/128/445/1743/8802/4967/50/216/151742/4942/34/501/4953/126/8639/5166"
"WP3580","Methionine De Novo and Salvage Pathway",19,-0.478745096628679,-1.05656757268741,0.39622641509434,0.59811834867102,0.451174205628719,1610,"tags=26%, list=13%, signal=23%","22921/4144/4953/4482/253827"
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex",19,0.424824309717974,1.03120991796317,0.398907103825137,0.600528629128059,0.452992334721337,841,"tags=21%, list=7%, signal=20%","1786/1789/6597/1788"
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds",16,-0.496436941953631,-1.05260950912558,0.406148867313916,0.608417584547305,0.458943152318601,3103,"tags=44%, list=25%, signal=33%","8325/324/1452/27122/4035/6925/8324"
"WP561","Heme Biosynthesis",8,0.536905292600347,1.06598980362513,0.407766990291262,0.608417584547305,0.458943152318601,923,"tags=25%, list=8%, signal=23%","3145/1371"
"WP528","Acetylcholine Synthesis",4,0.658824636227273,1.10386282601906,0.407894736842105,0.608417584547305,0.458943152318601,4091,"tags=50%, list=33%, signal=33%","10400/5130"
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ",71,-0.372089318190405,-1.02956901010671,0.409271523178808,0.608417584547305,0.458943152318601,2761,"tags=32%, list=23%, signal=25%","4089/1452/387/7042/8313/5900/842/1647/51426/83439/10912/1026/5743/3725/5602/7043/4609/10000/9423/4616/596/2353/7048"
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation",24,-0.443481904805737,-1.04147754420425,0.409638554216867,0.608417584547305,0.458943152318601,2689,"tags=33%, list=22%, signal=26%","650/6615/652/1432/1026/4882/7067/5745"
"WP2038","Regulation of Microtubule Cytoskeleton",42,0.348257037634053,1.02820961176323,0.410958904109589,0.608560606060606,0.459051036682616,700,"tags=17%, list=6%, signal=16%","11004/983/9212/3984/3925/2048/2932"
"WP3965","Lipid Metabolism Pathway",26,0.382971929168465,1.02630159267562,0.411931818181818,0.608560606060606,0.459051036682616,485,"tags=12%, list=4%, signal=11%","47/2194/29923"
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation",16,-0.491140684329963,-1.04137970194098,0.414239482200647,0.610342215795635,0.460394945223004,3285,"tags=44%, list=27%, signal=32%","1632/788/1374/3033/3030/2182/34"
"WP688","Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)",3,-0.712133862471584,-1.09656268009355,0.415384615384615,0.610406039583758,0.460443088950698,3267,"tags=100%, list=27%, signal=73%","2329/2327"
"WP3934","Leptin and adiponectin",8,-0.573487917528864,-1.06514996969126,0.422033898305085,0.618536454129675,0.466576044631352,601,"tags=38%, list=5%, signal=36%","5564/1374/3953"
"WP2875","Constitutive Androstane Receptor Pathway",17,-0.489757470924579,-1.04988894675634,0.423510466988728,0.61906279343471,0.46697307428003,1104,"tags=29%, list=9%, signal=27%","8648/1577/2308/5243/10891"
"WP4562","Canonical NF-KB pathway",8,-0.568421982425598,-1.05574091248748,0.430508474576271,0.627636039250669,0.473440067608808,2399,"tags=50%, list=20%, signal=40%","3551/5970/4792/4790"
"WP75","Toll-like Receptor Signaling Pathway",78,-0.362702475922421,-1.01692564660777,0.432679738562092,0.628528292558029,0.474113114469955,3277,"tags=36%, list=27%, signal=26%","929/7189/5293/5601/5606/5595/8503/148022/23533/7096/23118/6351/5970/54472/23643/4792/7100/8737/4790/1432/7098/7099/3725/5602/10000/1326/2353/3569"
"WP3630","NAD metabolism, sirtuins and aging",10,-0.542314954224904,-1.0498327059165,0.433389544688027,0.628528292558029,0.474113114469955,1683,"tags=60%, list=14%, signal=52%","10135/2309/23410/4790/2308/23411"
"WP3601","Composition of Lipid Particles",4,-0.670261620451634,-1.08578674875219,0.435100548446069,0.629362151015986,0.474742112774741,2933,"tags=75%, list=24%, signal=57%","3931/4023/3949"
"WP4673","Genes involved in male infertility",85,-0.355778128499587,-1.01129506019891,0.436477987421384,0.629710429769392,0.475004827319872,1950,"tags=26%, list=16%, signal=22%","367/8476/472/6648/7057/9194/4780/355/6948/4846/340719/7320/8787/2099/143689/3983/4524/5243/596/2775/1191/6649"
"WP4147","PTF1A related regulatory pathway",5,-0.629330677952683,-1.06205177893462,0.445255474452555,0.640705280121339,0.483298491750278,1496,"tags=60%, list=12%, signal=53%","4851/3516/8850"
"WP4148","Splicing factor NOVA regulated synaptic proteins",31,-0.409975035937273,-1.00224093328974,0.453030303030303,0.650204113675616,0.490463676855823,1120,"tags=26%, list=9%, signal=24%","23136/54386/4134/2054/2037/5332/3778/57863"
"WP3874","Canonical and Non-Canonical TGF-B signaling",17,-0.476239325149383,-1.02091021203031,0.455716586151369,0.651829147716037,0.491689476806511,3811,"tags=59%, list=31%, signal=41%","4087/4016/84171/5601/659/7040/4089/1432/657/7048"
"WP4189","Mevalonate arm of cholesterol biosynthesis pathway with inhibitors",2,0.739928233567118,1.06391770280984,0.456913827655311,0.651829147716037,0.491689476806511,3191,"tags=100%, list=26%, signal=74%","4597/3156"
"WP733","Serotonin Receptor 2 and STAT3 Signaling",3,-0.674414811189952,-1.03848188076122,0.457692307692308,0.651829147716037,0.491689476806511,3996,"tags=100%, list=33%, signal=67%","6774/3717"
"WP4504","Cysteine and methionine catabolism",13,-0.500665450554921,-1.01697870030491,0.46089850249584,0.654712231750501,0.493864252336973,248,"tags=23%, list=2%, signal=23%","4548/6821/1036"
"WP3998","Prader-Willi and Angelman Syndrome",30,-0.411344389066711,-0.999611884307602,0.464339908952959,0.657913835191661,0.496279294263897,942,"tags=20%, list=8%, signal=19%","5108/9638/4692/4487/627/894"
"WP3958","GPR40 Pathway",13,-0.499302365322767,-1.01420992797148,0.467554076539101,0.660777955108832,0.498439764731534,1720,"tags=46%, list=14%, signal=40%","23236/113026/2767/5336/5310/5334"
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway",117,-0.338410169831958,-0.991921535958344,0.485257985257985,0.683281348745235,0.515414583796044,3310,"tags=30%, list=27%, signal=22%","4216/10062/1977/5293/5601/5606/2309/5595/8503/7068/6655/5286/4023/9064/2889/7249/7786/23433/5170/57521/8660/1432/25759/5602/9252/5563/2308/4215/51422/7067/1326/6567/9020/6196/6517"
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling",64,0.309984767107206,0.989792867839255,0.485943775100402,0.683281348745235,0.515414583796044,2324,"tags=22%, list=19%, signal=18%","47/2194/6319/7528/6713/2224/6720/10483/6396/2475/1622/51141/3837/4597"
"WP311","Synthesis and Degradation of Ketone Bodies",5,-0.605008519773591,-1.02100596269431,0.489051094890511,0.68406826307577,0.516008171083186,2248,"tags=60%, list=18%, signal=49%","3158/5019/38"
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer",50,-0.381773624922786,-1.00088476159789,0.48951048951049,0.68406826307577,0.516008171083186,1745,"tags=22%, list=14%, signal=19%","7057/4790/308/1026/8870/7185/4092/25/7431/9021/3727"
"WP619","Type II interferon signaling (IFNG)",31,0.342459121029187,0.95577436203706,0.491228070175439,0.68406826307577,0.516008171083186,2344,"tags=29%, list=19%, signal=24%","5610/9636/2537/6773/3627/10379/6772/4938/4283"
"WP438","Non-homologous end joining",10,0.474872665082603,0.994288146872933,0.491442542787286,0.68406826307577,0.516008171083186,4169,"tags=50%, list=34%, signal=33%","5591/7518/27434/64421/7520"
"WP4262","Breast cancer pathway",121,-0.333874367961316,-0.98422130077366,0.496332518337408,0.689143396388281,0.51983645898945,1881,"tags=22%, list=15%, signal=19%","28514/5728/4855/1647/472/51426/83439/23493/81029/25759/10912/1026/6500/3725/4609/10000/2099/4616/3815/3479/2260/7482/8324/2252/2247/2353/5241"
"WP229","Irinotecan Pathway",7,-0.563966104721881,-1.00399818313346,0.507880910683012,0.702324456417485,0.529779230852634,2447,"tags=57%, list=20%, signal=46%","1577/9429/8824/1066"
"WP268","Notch Signaling",40,0.324497795656443,0.953651114614969,0.508361204013378,0.702324456417485,0.529779230852634,1485,"tags=18%, list=12%, signal=15%","2648/6868/3066/23385/151636/4854/51107"
"WP2324","AGE/RAGE pathway",63,-0.36423124058568,-0.987560696763441,0.51006711409396,0.70292831146282,0.530234732378377,3305,"tags=38%, list=27%, signal=28%","3958/6774/5601/5595/4313/5321/4478/387/5970/6093/842/4303/5578/4792/6776/4790/1432/3725/3717/4846/2308/6777/3625/5579"
"WP4286","Genotoxicity pathway",49,-0.376474636301815,-0.978146277572307,0.513437057991513,0.705373058314235,0.532078860252235,1725,"tags=43%, list=14%, signal=37%","84312/10210/11072/23002/91947/79671/10346/9209/9693/1647/6232/80271/1026/1263/5734/7832/1052/29950/3398/59/3708"
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma",56,0.311216213099264,0.982447898682645,0.514492753623188,0.705373058314235,0.532078860252235,1134,"tags=12%, list=9%, signal=11%","29128/672/1111/4602/11200/5591/4613"
"WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer",5,-0.593999882996221,-1.00242790400014,0.516423357664234,0.705373058314235,0.532078860252235,4229,"tags=80%, list=34%, signal=52%","5594/6774/5595/3716"
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway",19,-0.445557685887425,-0.983324541567945,0.517295597484277,0.705373058314235,0.532078860252235,1638,"tags=32%, list=13%, signal=27%","5162/54583/6194/4780/8452/32"
"WP4357","NRF2-ARE regulation",22,0.371107876406758,0.951850833210632,0.518207282913165,0.705373058314235,0.532078860252235,1798,"tags=27%, list=15%, signal=23%","192111/2048/2932/7965/2730/7525"
"WP2261","Signaling Pathways in Glioblastoma",80,0.284174568402245,0.950717137142876,0.521186440677966,0.707689431704885,0.533826153119589,917,"tags=11%, list=7%, signal=10%","898/672/675/1869/1017/1019/5590/2956/4893"
"WP2272","Pathogenic Escherichia coli infection",47,-0.372620797969452,-0.969232106851218,0.523076923076923,0.708519842016175,0.534452550409313,2636,"tags=34%, list=21%, signal=27%","387/9475/6093/3688/23643/5578/7846/347733/7280/7454/7100/60/7099/25/2534/84617"
"WP3938","miR-222 in Exercise-Induced Cardiac Growth",4,-0.626519846079316,-1.01492749390127,0.524680073126143,0.708957952468007,0.534783027037429,4508,"tags=100%, list=37%, signal=63%","204851/28996/79618"
"WP2643","Nanoparticle-mediated activation of receptor signaling",28,-0.398351712590285,-0.955337128730705,0.526717557251908,0.709979383741015,0.535553515761321,2266,"tags=25%, list=18%, signal=20%","3688/3672/1432/5602/374/7094/10000"
"WP2332","Interleukin-11 Signaling Pathway",40,-0.373929955938385,-0.955277136178694,0.529160739687055,0.711541382977254,0.536731767132757,1337,"tags=18%, list=11%, signal=16%","2242/3717/2534/3590/596/9021/3572"
"WP1742","TP53 Network",18,-0.443422954343401,-0.962602077462073,0.5328,0.714700242130751,0.539114566076208,2012,"tags=39%, list=16%, signal=33%","1647/472/666/1026/4609/25/596"
"WP2447","Amyotrophic lateral sclerosis (ALS)",30,-0.393197626468694,-0.955513265153361,0.541729893778452,0.724923577664885,0.546826259420406,1065,"tags=17%, list=9%, signal=15%","1432/1471/5532/596/5533"
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling",56,-0.356753713667904,-0.950685389233134,0.544077134986226,0.726246124782019,0.547823886639676,1858,"tags=21%, list=15%, signal=18%","1938/29904/23236/51719/84254/1026/5563/133522/51422/3953/32/6517"
"WP702","Metapathway biotransformation Phase I and II",90,-0.331884947921445,-0.946397988412624,0.545340050377834,0.726246124782019,0.547823886639676,2669,"tags=21%, list=22%, signal=17%","1545/9420/2327/57016/1577/2052/285440/8514/9469/4837/113612/57404/7881/1593/51302/2053/11185/2949/2878"
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits",17,0.396598575627267,0.942682060912279,0.551181102362205,0.732264582035159,0.552363745141475,1014,"tags=18%, list=8%, signal=16%","7472/7428/10631"
"WP1946","Cori Cycle",14,-0.456007027019577,-0.939834846096625,0.55810147299509,0.739533190404919,0.557846620921058,115,"tags=14%, list=1%, signal=14%","3098/6517"
"WP254","Apoptosis",80,0.280738859164702,0.939222837463855,0.559322033898305,0.739533190404919,0.557846620921058,1927,"tags=21%, list=16%, signal=18%","835/332/637/3070/1676/3663/7186/8718/1677/317/839/581/56616/3661/8772/27113/10018"
"WP1602","Nicotine Activity on Dopaminergic Neurons",11,-0.478741547452283,-0.945573554828799,0.563636363636364,0.743463203463203,0.560811118705856,1403,"tags=55%, list=11%, signal=48%","2770/108/54331/6571/84152/3777"
"WP4685","Melanoma",63,-0.346530021316886,-0.939566383023237,0.566442953020134,0.743776084989639,0.561047132321654,3203,"tags=38%, list=26%, signal=28%","5293/2113/5595/8503/6655/805/91860/808/801/5728/3791/1647/51426/8649/25759/80243/10912/1026/7414/10000/4286/4616/3815/2353"
"WP2583","T-Cell Receptor and Co-stimulatory Signaling",27,-0.389492100945826,-0.929378585113825,0.566615620214395,0.743776084989639,0.561047132321654,3626,"tags=59%, list=30%, signal=42%","1859/926/7535/5133/805/5530/1452/801/5728/5578/4773/4792/940/3702/4790/2534"
"WP710","DNA Damage Response (only ATM dependent)",100,-0.324478661041044,-0.936286348383179,0.567901234567901,0.743776084989639,0.561047132321654,3203,"tags=33%, list=26%, signal=25%","5293/5601/2309/8503/324/5934/6655/5286/896/7040/23533/847/4089/387/4791/5527/5728/472/6648/83439/81029/4790/3949/1026/3725/5602/8061/4609/25/10000/7482/596/894"
"WP205","IL-7 Signaling Pathway",25,-0.392890589566424,-0.926693469061768,0.569486404833837,0.744093085561192,0.561286253026398,3595,"tags=44%, list=29%, signal=31%","3561/5295/6774/5595/2185/3716/6776/3574/4609/2534/6777"
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus",15,-0.444386279064418,-0.928788809791323,0.579638752052545,0.752631818285169,0.567727212348873,2115,"tags=33%, list=17%, signal=28%","2531/7357/64781/166929/256435"
"WP2854","Gene regulatory network modelling somitogenesis ",6,0.489435363281967,0.915875388924504,0.579646017699115,0.752631818285169,0.567727212348873,1965,"tags=33%, list=16%, signal=28%","2043/3280"
"WP4153","Degradation pathway of sphingolipids, including diseases",8,0.46703712510794,0.927271196877625,0.580097087378641,0.752631818285169,0.567727212348873,4395,"tags=62%, list=36%, signal=40%","2717/2720/10825/4758/3073"
"WP3286","Copper homeostasis",47,-0.358460039965461,-0.932398249509891,0.586013986013986,0.755984072301015,0.570255893413459,1719,"tags=19%, list=14%, signal=17%","4502/4137/5621/3725/4493/261729/2308/79689/6649"
"WP4150","Wnt Signaling in Kidney Disease",27,-0.383594467756489,-0.915306068686108,0.586523736600306,0.755984072301015,0.570255893413459,1730,"tags=19%, list=14%, signal=16%","81029/5602/8322/7482/8324"
"WP4536","Genes related to primary cilium development (based on CRISPR)",95,0.274731147313717,0.94925630038194,0.588235294117647,0.755984072301015,0.570255893413459,2624,"tags=22%, list=21%, signal=18%","163786/79867/79989/89891/11116/57560/51259/150737/23322/27077/79959/26005/10300/54903/90410/84314/255758/55125/79598/8481/9851"
"WP231","TNF alpha Signaling Pathway",88,-0.327383221507801,-0.931874255474766,0.588679245283019,0.755984072301015,0.570255893413459,1891,"tags=18%, list=15%, signal=15%","4792/8737/7128/4790/8837/6500/3725/7185/7133/4215/6401/330/1326/6347/9020/3569"
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway",32,-0.375012362210511,-0.921374057811769,0.591251885369532,0.755984072301015,0.570255893413459,2399,"tags=22%, list=20%, signal=18%","5970/842/22900/4792/9744/22861/114548"
"WP106","Alanine and aspartate metabolism",7,0.469043983936996,0.904103867559653,0.591647331786543,0.755984072301015,0.570255893413459,621,"tags=14%, list=5%, signal=14%","2571"
"WP288","NLR Proteins",8,0.456836936854127,0.90701940047428,0.592233009708738,0.755984072301015,0.570255893413459,654,"tags=12%, list=5%, signal=12%","2048"
"WP4537","Hippo-Yap signaling pathway",23,-0.39246252720153,-0.911247991183471,0.597560975609756,0.759400894071044,0.572833279396171,1771,"tags=22%, list=14%, signal=19%","11186/7005/7003/23043/26524"
"WP4533","Transcription co-factors SKI and SKIL protein partners",18,-0.421159708669777,-0.914272043289141,0.5984,0.759400894071044,0.572833279396171,1983,"tags=28%, list=16%, signal=23%","6497/7005/4204/7003/26524"
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B",10,0.431076979671557,0.902588762826886,0.599022004889976,0.759400894071044,0.572833279396171,3510,"tags=70%, list=29%, signal=50%","5590/84962/7335/3552/3654/92610/7334"
"WP4586","Metabolism of alpha-linolenic acid",6,0.478060227106553,0.894589212954575,0.603982300884956,0.76394108376773,0.576258047227415,2459,"tags=50%, list=20%, signal=40%","246/3992/9415"
"WP699","Aflatoxin B1 metabolism",3,-0.597592161121822,-0.920188318988681,0.619230769230769,0.779215861294816,0.587780157579407,2384,"tags=67%, list=19%, signal=54%","2944/2052"
"WP3924","Hfe effect on hepcidin production",4,-0.563536647726731,-0.912898196566318,0.619744058500914,0.779215861294816,0.587780157579407,1088,"tags=75%, list=9%, signal=68%","3397/654/4092"
"WP237","Glucocorticoid and Mineralcorticoid Metabolism",2,-0.6428745272125,-0.92465908899689,0.620278330019881,0.779215861294816,0.587780157579407,1591,"tags=100%, list=13%, signal=87%","3290"
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway",62,-0.331787423125432,-0.899655840084374,0.623497997329773,0.781488440092069,0.589494415193903,1720,"tags=23%, list=14%, signal=20%","23236/1432/2770/3725/5908/3717/5906/108/54331/4609/5144/2775/1958/2353"
"WP3646","Hepatitis C and Hepatocellular Carcinoma",44,-0.344975408820757,-0.897234872231366,0.629009762900976,0.786617175275713,0.593363136204556,2231,"tags=30%, list=18%, signal=24%","842/3716/960/4790/1432/1026/5743/3725/2487/4609/3570/330/3569"
"WP391","Mitochondrial Gene Expression",16,-0.419460147003083,-0.88939339948617,0.634304207119741,0.791451645820578,0.597009886739064,1861,"tags=19%, list=15%, signal=16%","50804/133522/10891"
"WP4297","Thiamine metabolic pathways",8,-0.468836872681198,-0.870779602259688,0.638983050847458,0.79549800038088,0.600062143551604,1981,"tags=38%, list=16%, signal=31%","10560/4967/27010"
"WP244","Alpha 6 Beta 4 signaling pathway",33,-0.361285764977268,-0.891926316739816,0.645112781954887,0.800617253710871,0.603923712185475,2636,"tags=24%, list=21%, signal=19%","387/3915/5578/8660/1432/2549/3913/3908"
"WP501","GPCRs, Class C Metabotropic glutamate, pheromone",5,-0.512767588583115,-0.865341145304311,0.645985401459854,0.800617253710871,0.603923712185475,4051,"tags=80%, list=33%, signal=54%","9052/2550/693199/51704"
"WP3633","Caffeine and Theobromine metabolism",1,0.674957188289978,0.900912100245784,0.661764705882353,0.817689026461817,0.61680133670025,3987,"tags=100%, list=33%, signal=67%","7498"
"WP4742","Ketogenesis and Ketolysis",8,-0.457744698085562,-0.850177896324434,0.66271186440678,0.817689026461817,0.61680133670025,3007,"tags=38%, list=25%, signal=28%","788/5019/38"
"WP2889","Oxytocin signaling",2,-0.622166041428804,-0.894873666198628,0.667992047713718,0.821435487172678,0.619627376795655,4636,"tags=100%, list=38%, signal=62%","2776"
"WP4228","Vitamin B6-dependent and responsive disorders",4,-0.531143599047165,-0.860423249568372,0.669104204753199,0.821435487172678,0.619627376795655,1856,"tags=50%, list=15%, signal=42%","10157/501"
"WP4389","Bile Acids synthesis and enterohepatic circulation ",5,-0.499086511662036,-0.842253104961129,0.671532846715328,0.821435487172678,0.619627376795655,4590,"tags=80%, list=37%, signal=50%","2264/5594/5595/3949"
"WP4584","Biomarkers for pyrimidine metabolism disorders",12,0.388444767238018,0.852851352575445,0.671679197994987,0.821435487172678,0.619627376795655,1862,"tags=42%, list=15%, signal=35%","6241/7298/80324/1890/7372"
"WP3930","EDA Signalling in Hair Follicle Development",9,-0.445264201303959,-0.84836309933393,0.673949579831933,0.822396623847777,0.620352383939896,1663,"tags=56%, list=14%, signal=48%","4050/5727/1896/2735/22943"
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)",10,-0.436647435816791,-0.845277740368078,0.676222596964587,0.823356744436002,0.621076624626815,1060,"tags=30%, list=9%, signal=27%","4609/9021/3572"
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder",39,-0.337278515533572,-0.86131472773095,0.681365576102418,0.827799406054254,0.624427824821468,3203,"tags=41%, list=26%, signal=30%","5293/7337/5595/8503/1742/7249/8831/5728/57521/85358/5563/775/10000/4915/51422/627"
"WP3858","Toll-like Receptor Signaling related to MyD88",27,-0.354626754015956,-0.846185352900645,0.686064318529862,0.831481071191189,0.627204988149158,3725,"tags=56%, list=30%, signal=39%","7187/5594/51284/114609/3551/7189/148022/7096/4791/5970/54472/7100/4790/7098/7099"
"WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway",14,-0.401734107105304,-0.827977838830255,0.687397708674304,0.831481071191189,0.627204988149158,1871,"tags=43%, list=15%, signal=36%","7189/7096/7100/4790/7099/3725"
"WP3926","ApoE and miR-146 in inflammation and atherosclerosis",8,-0.439829238010611,-0.816903173052031,0.698305084745763,0.842137953579601,0.635243715696564,3220,"tags=50%, list=26%, signal=37%","7189/4791/5970/7099"
"WP534","Glycolysis and Gluconeogenesis",33,-0.349405814527868,-0.862597620526027,0.699248120300752,0.842137953579601,0.635243715696564,787,"tags=6%, list=6%, signal=6%","6515/6517"
"WP4220","Neurotransmitter Disorders",1,-0.64918861616244,-0.870112063601179,0.701520912547528,0.842280412128963,0.635351175404139,4304,"tags=100%, list=35%, signal=65%",""
"WP1495","Glycine Metabolism",3,0.564656300416955,0.870111828885615,0.703319502074689,0.842280412128963,0.635351175404139,161,"tags=33%, list=1%, signal=33%","6472"
"WP581","EPO Receptor Signaling",25,-0.355405310621097,-0.838278617428573,0.70392749244713,0.842280412128963,0.635351175404139,2221,"tags=28%, list=18%, signal=23%","6774/5595/5788/6776/8660/3717/6777"
"WP4661","Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension)",2,0.594586749437303,0.854936113915871,0.707414829659319,0.844628912998411,0.637122702755784,955,"tags=50%, list=8%, signal=46%","84706"
"WP4566","Translation inhibitors in chronically activated PDGFRA cells",45,-0.326772283210191,-0.850829012276327,0.712100139082058,0.848394574304216,0.639963226294459,3254,"tags=38%, list=27%, signal=28%","1977/5601/5606/5595/6194/8503/1974/5292/57521/5578/1432/5602/27250/1975/9252/10000/6196"
"WP3869","Cannabinoid receptor signaling",23,-0.35610173244223,-0.82682285786308,0.714939024390244,0.84905430664671,0.640460877329933,3336,"tags=35%, list=27%, signal=25%","135/5601/5567/5595/5573/1432/5602/5577"
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation",40,0.288222726046106,0.84704404045395,0.71571906354515,0.84905430664671,0.640460877329933,2274,"tags=28%, list=19%, signal=22%","4001/84823/1676/5591/1677/317/839/8772/5062/8767/836"
"WP422","MAPK Cascade",33,-0.34457466152478,-0.850670683676129,0.717293233082707,0.849103528050897,0.640498006148976,1744,"tags=36%, list=14%, signal=31%","5606/5595/6655/4155/7786/8649/1432/3725/5602/22821/4215/6237"
"WP2828","Bladder Cancer",38,0.295652153465674,0.853433064626222,0.721854304635762,0.851150436959116,0.642042035859337,1317,"tags=16%, list=11%, signal=14%","1869/1019/4312/4893/1890/4318"
"WP1604","Codeine and Morphine Metabolism",4,-0.502592805112083,-0.81417254271725,0.722120658135283,0.851150436959116,0.642042035859337,679,"tags=25%, list=6%, signal=24%","5243"
"WP3303","RAC1/PAK1/p38/MMP2 Pathway",62,-0.30955130342258,-0.839361647004237,0.723631508678238,0.851150436959116,0.642042035859337,2399,"tags=26%, list=20%, signal=21%","5970/3688/842/9046/4792/6776/4790/1432/2308/284/7010/4609/6777/10413/7075/9068"
"WP524","G13 Signaling Pathway",35,0.300015740922837,0.851575333280643,0.728971962616822,0.854866761462783,0.644845343531683,602,"tags=11%, list=5%, signal=11%","11113/3984/6242/1072"
"WP61","Notch Signaling Pathway Netpath",57,-0.316513634190585,-0.847327214322279,0.72987721691678,0.854866761462783,0.644845343531683,2251,"tags=40%, list=18%, signal=33%","5295/83464/55534/8650/9611/6774/4853/9612/84441/55294/7088/28514/4855/23493/4790/3516/1026/6015/4137/6500/3717/4609/2273"
"WP4655","Cytosolic DNA-sensing pathway",55,-0.316213084825049,-0.841551911854024,0.738950276243094,0.86366762244446,0.65148403213082,2466,"tags=18%, list=20%, signal=15%","6351/5970/84265/4792/1540/8737/4790/54941/90865/3569"
"WP2507","Nanomaterial induced apoptosis",19,0.331158454597987,0.803847319908567,0.743169398907104,0.865393198250469,0.652785673010519,2274,"tags=37%, list=19%, signal=30%","637/317/839/581/56616/8772/836"
"WP3676","BDNF-TrkB Signaling",30,-0.340250979753723,-0.82684711898177,0.743550834597876,0.865393198250469,0.652785673010519,1751,"tags=23%, list=14%, signal=20%","1742/7249/29904/9846/2549/4915/627"
"WP4506","Tyrosine Metabolism",1,0.627252711408301,0.837237631399127,0.745798319327731,0.866189242992795,0.653386147573892,4572,"tags=100%, list=37%, signal=63%","2184"
"WP4658","Small cell lung cancer",89,-0.299534904328356,-0.852629876475416,0.74968394437421,0.867432150313152,0.654323700692232,2399,"tags=31%, list=20%, signal=25%","5970/3915/7188/3688/842/5728/1647/4792/2272/51426/4790/3910/10912/1026/5743/6500/7185/4609/1288/10000/3913/4616/1028/330/1286/596/10319/3908"
"WP585","Interferon type I signaling pathways",52,-0.31254966486388,-0.824157827280662,0.75,0.867432150313152,0.654323700692232,3524,"tags=46%, list=29%, signal=33%","5295/7535/1398/6774/1977/5293/5606/8554/6194/2889/7409/5788/3716/57521/6776/8660/1432/9846/5906/27250/1975/9252/2534/9021"
"WP2059","Alzheimers Disease",69,-0.304595659022824,-0.84223421026692,0.754293262879789,0.869806763285024,0.656114924993644,1536,"tags=19%, list=13%, signal=17%","23236/4035/355/4137/6622/775/489/5332/5532/322/6263/5533/3708"
"WP1772","Apoptosis Modulation and Signaling",79,-0.299443406685835,-0.842333733770823,0.755874673629243,0.869806763285024,0.656114924993644,2231,"tags=25%, list=18%, signal=21%","842/54472/8738/4792/8737/4790/666/8837/355/5587/8793/3725/4170/9531/599/7133/330/596/9020/2353"
"WP4558","Overview of interferons-mediated signaling pathway",14,0.349355720319286,0.792137180046499,0.757033248081841,0.869806763285024,0.656114924993644,2081,"tags=29%, list=17%, signal=24%","7297/6773/10379/6772"
"WP4205","MET in type 1 papillary renal cell carcinoma",52,-0.310138843898992,-0.817800767293892,0.758333333333333,0.869806763285024,0.656114924993644,1465,"tags=33%, list=12%, signal=29%","5295/1398/6774/5293/2113/5595/8503/6655/2889/7030/1026/3725/5908/2549/5906/10000/3082"
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells",18,-0.36314123798396,-0.788322992013622,0.76,0.869917355371901,0.656198347107438,3131,"tags=33%, list=26%, signal=25%","5595/5869/22800/22808/6237/5873"
"WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma",7,-0.43315921984253,-0.771129800334142,0.763572679509632,0.870904389971442,0.656942889642148,2463,"tags=43%, list=20%, signal=34%","7423/55662/7424"
"WP26","Signal Transduction of S1P Receptor",24,-0.339032448465089,-0.796187348360122,0.765060240963855,0.870904389971442,0.656942889642148,1720,"tags=25%, list=14%, signal=22%","23236/1903/2770/9294/10000/1901"
"WP2878","PPAR Alpha Pathway",16,0.338857283807798,0.792631802422734,0.768229166666667,0.870904389971442,0.656942889642148,487,"tags=12%, list=4%, signal=12%","983/1019"
"WP22","IL-9 Signaling Pathway",15,-0.37261138822411,-0.778775817543178,0.768472906403941,0.870904389971442,0.656942889642148,3595,"tags=47%, list=29%, signal=33%","3561/5295/6774/5595/3716/6776/6777"
"WP691","Tamoxifen metabolism",5,0.408856097920705,0.726793716580559,0.768722466960352,0.870904389971442,0.656942889642148,937,"tags=20%, list=8%, signal=18%","54575"
"WP2586","Aryl Hydrocarbon Receptor Netpath",40,-0.319424385397628,-0.816032006161509,0.772403982930299,0.871836837466952,0.657646255888999,3002,"tags=40%, list=24%, signal=30%","57491/9612/405/4023/1545/5970/948/4790/4780/5325/1026/5743/135112/4609/2099/1316"
"WP1471","Target Of Rapamycin (TOR) Signaling",34,-0.322633578752431,-0.802786397434725,0.772795216741405,0.871836837466952,0.657646255888999,2564,"tags=21%, list=21%, signal=16%","7249/57521/5578/58528/10670/5563/51422"
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling",19,0.325936654269272,0.791172027639702,0.775956284153005,0.871836837466952,0.657646255888999,700,"tags=11%, list=6%, signal=10%","5210/2932"
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein",20,-0.353255099266149,-0.788484357680968,0.776729559748428,0.871836837466952,0.657646255888999,1679,"tags=25%, list=14%, signal=22%","666/4170/599/4609/596"
"WP3644","NAD+ metabolism",14,-0.369666930244778,-0.761887080478472,0.777414075286416,0.871836837466952,0.657646255888999,2913,"tags=50%, list=24%, signal=38%","64802/10135/349565/23410/203447/4907/23411"
"WP3300","Dual hijack model of Vif in HIV infection",6,0.393335491018856,0.736044680954459,0.780973451327434,0.874059175829087,0.659322616006361,3874,"tags=50%, list=32%, signal=34%","865/861/60489"
"WP2853","Endoderm Differentiation",112,-0.285082935557912,-0.832351189288985,0.784146341463415,0.875840873328088,0.660666590749099,1778,"tags=28%, list=14%, signal=24%","4089/655/6001/58499/1846/1488/2736/79776/55809/23576/3915/5087/83439/23373/657/5090/57690/1844/57198/22943/2308/9760/83595/3087/1112/6925/2908/1847/2627/6422/64321"
"WP2369","Histone Modifications",30,0.293782338080948,0.808049187938813,0.790087463556851,0.880701116318905,0.664332782022811,2259,"tags=30%, list=18%, signal=25%","2146/56950/9869/79723/6839/10322/55209/54093/10919"
"WP4156","Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases",2,-0.548523894960039,-0.788952717112593,0.799204771371769,0.888176352705411,0.669971521991351,5539,"tags=100%, list=45%, signal=55%","2643"
"WP2533","Glycerophospholipid Biosynthetic Pathway",25,0.300461718808301,0.789449798660725,0.8,0.888176352705411,0.669971521991351,1962,"tags=28%, list=16%, signal=24%","9791/9489/114971/5833/10400/54675/10390"
"WP4236","Disorders of the Krebs cycle",7,-0.408203612495765,-0.726702689865331,0.80385288966725,0.890669001751314,0.671851783574523,2454,"tags=57%, list=20%, signal=46%","8803/8801/1743/8802"
"WP1531","Vitamin D Metabolism",7,0.367983239879823,0.709304631902429,0.807424593967517,0.892840768578852,0.673489996438921,409,"tags=14%, list=3%, signal=14%","1717"
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis",16,-0.354703273062449,-0.7520875394047,0.812297734627832,0.896440129449838,0.676205075796287,1534,"tags=25%, list=13%, signal=22%","3949/5465/23411/10891"
"WP4656","Joubert Syndrome",69,0.264259729226251,0.856645256448958,0.816326530612245,0.899095224570942,0.678207874130085,2083,"tags=19%, list=17%, signal=16%","117177/261734/9094/79867/95681/51259/23322/27077/51524/79848/284086/54903/2475"
"WP1434","Osteopontin Signaling",13,0.324668896796456,0.730171807204141,0.820448877805486,0.901842615683015,0.680280293418501,1846,"tags=31%, list=15%, signal=26%","6696/5328/4318/5604"
"WP107","Translation Factors",47,-0.298875767979579,-0.777412296533625,0.823776223776224,0.903706986083224,0.681686630201482,2455,"tags=30%, list=20%, signal=24%","8666/9086/8661/1938/29904/2107/8665/10209/1975/1936/8637/1933/1979/1915"
"WP4549","Fragile X Syndrome ",93,-0.285343976212467,-0.818070336810576,0.826899128268991,0.905135970429732,0.68276454543151,2758,"tags=26%, list=22%, signal=20%","5530/1374/64798/1742/7249/1212/5573/8831/5728/57521/5578/8536/23236/1845/2549/26999/4204/2534/4915/1979/4131/1915/627/3708"
"WP4726","Sphingolipid Metabolism (integrated pathway)",21,-0.333054891894799,-0.750247495877166,0.828346456692913,0.905135970429732,0.68276454543151,2115,"tags=33%, list=17%, signal=28%","259230/2531/7357/64781/79603/166929/6609"
"WP497","Urea cycle and metabolism of amino groups",16,0.313718055016933,0.733827836327903,0.830729166666667,0.905952673884514,0.683380603329189,691,"tags=19%, list=6%, signal=18%","5831/162417/5832"
"WP4725","Sphingolipid Metabolism (general overview)",20,-0.33379024713508,-0.745037762113618,0.833333333333333,0.907007203667322,0.684176059008031,2115,"tags=35%, list=17%, signal=29%","259230/2531/7357/64781/79603/166929/6609"
"WP3","Phytochemical activity on NRF2 transcriptional activation",14,0.319043257214972,0.723406005352206,0.838874680306905,0.911248182137305,0.68737512503992,2452,"tags=29%, list=20%, signal=23%","2048/7965/2730/1728"
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway",51,-0.293883067794566,-0.771758078218806,0.841004184100418,0.91177361642198,0.68777147201126,2893,"tags=29%, list=24%, signal=23%","79671/9755/10010/5970/10521/4792/1540/8737/4790/1432/1654/5602/8653/54941/6387"
"WP400","p38 MAPK Signaling Pathway",33,-0.304011953252267,-0.750531263600248,0.84812030075188,0.917692669172932,0.692236347447566,2732,"tags=24%, list=22%, signal=19%","5321/7042/9261/8737/1432/9252/4609/4209"
"WP4018","Pathways in clear cell renal cell carcinoma",79,0.25229560335728,0.842203228281442,0.851694915254237,0.919764099514322,0.69379887422988,2109,"tags=18%, list=17%, signal=15%","47/6472/2194/2023/7428/7167/5723/29968/8242/5230/5232/2597/2475/2821"
"WP4255","Non-small cell lung cancer",67,-0.281011494924726,-0.774223659536101,0.855453350854139,0.92156868740922,0.695160115716246,3262,"tags=34%, list=27%, signal=25%","6774/5293/2309/5595/8503/5915/6655/83593/6257/842/5578/1647/2272/6776/51426/11186/10912/1026/5336/10000/6777/4616/5579"
"WP2509","Nanoparticle triggered autophagic cell death",21,-0.320385420804169,-0.721707939212027,0.856692913385827,0.92156868740922,0.695160115716246,1266,"tags=43%, list=10%, signal=38%","55626/115201/7248/3643/55054/51100/7249/84557/596"
"WP3645","NAD+ biosynthetic pathways",17,-0.333743557394139,-0.715443240299662,0.863123993558776,0.92668738843326,0.69902126773324,1101,"tags=18%, list=9%, signal=16%","23410/683/23411"
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities",30,-0.303552256470985,-0.737665204976397,0.8649468892261,0.926848310698761,0.699142655039727,2564,"tags=33%, list=21%, signal=26%","2309/8503/7249/2887/4303/5728/57521/4846/2308/7942"
"WP3871","Valproic acid pathway",8,-0.354117393758488,-0.657708941548915,0.874576271186441,0.935357633662719,0.705561429914686,4053,"tags=62%, list=33%, signal=42%","3712/18/3032/3030/36"
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling",33,0.266889824586803,0.752958011527713,0.878338278931751,0.937571110844297,0.707231105843028,1694,"tags=15%, list=14%, signal=13%","332/637/581/3486/5230"
"WP4263","Pancreatic adenocarcinoma pathway",85,0.248569587245435,0.826221845050004,0.884057971014493,0.941861761426979,0.71046764067359,487,"tags=7%, list=4%, signal=7%","5888/5881/675/1869/1870/1019"
"WP4299","Lamin A-processing pathway",3,0.417859057608152,0.643903394973845,0.892116182572614,0.947497157489418,0.714718547450692,939,"tags=33%, list=8%, signal=31%","23463"
"WP4159","GABA receptor Signaling",13,0.29198885062978,0.656675243152314,0.892768079800499,0.947497157489418,0.714718547450692,1844,"tags=15%, list=15%, signal=13%","2571/1175"
"WP2249","Metastatic brain tumor",6,-0.363405157407161,-0.627512345181194,0.901818181818182,0.955272031983313,0.72058331122435,1060,"tags=50%, list=9%, signal=46%","1021/5295/4609"
"WP1422","Sphingolipid pathway",24,-0.290934958053864,-0.683234698763713,0.903614457831325,0.955348109997241,0.720640698591877,2615,"tags=33%, list=21%, signal=26%","259230/57704/2531/7357/64781/79603/166929/57515"
"WP694","Arylamine metabolism",2,-0.419262763007666,-0.603033886214071,0.914512922465209,0.965028874372811,0.727943118232958,7124,"tags=100%, list=58%, signal=42%","6817"
"WP3655","Hypothetical Craniofacial Development Pathway",6,-0.335571088516203,-0.579449676037149,0.92,0.968973384030418,0.730918551130678,2636,"tags=50%, list=21%, signal=39%","9411/387/7043"
"WP4271","Vitamin B12 Disorders",9,0.292736997164498,0.597017650972464,0.923832923832924,0.971164022397419,0.73257099922435,1425,"tags=22%, list=12%, signal=20%","81693/25974"
"WP138","Androgen receptor signaling pathway",82,-0.262246132215985,-0.741717122527783,0.926829268292683,0.972468588322247,0.733555062823356,2761,"tags=38%, list=23%, signal=29%","1387/9611/6774/7337/8554/7329/9612/9604/4089/2274/387/8648/573/9475/5970/6093/5728/8031/367/10273/10524/1026/3725/2308/8850/11034/7041/23411/2316/388/857"
"WP1941","Peroxisomal beta-oxidation of tetracosanoyl-CoA",4,0.321451876019576,0.538593666326844,0.940789473684211,0.985250223858323,0.743196539752525,8323,"tags=100%, list=68%, signal=32%","51/30/6342/3295"
"WP4523","Classical pathway of steroidogenesis, including diseases",5,-0.324685068678876,-0.547935079067982,0.950729927007299,0.991532536782858,0.747935430558226,3207,"tags=60%, list=26%, signal=44%","1528/9563/3290"
"WP4313","Ferroptosis",36,0.246439549625049,0.702335430330283,0.950819672131147,0.991532536782858,0.747935430558226,2414,"tags=22%, list=20%, signal=18%","7037/55240/246/4891/2730/6520/2937/10162"
"WP4674","Head and Neck Squamous Cell Carcinoma",66,-0.247363217128008,-0.678434843447439,0.953703703703704,0.991532536782858,0.747935430558226,3879,"tags=36%, list=32%, signal=25%","7248/4851/79109/1021/5925/5295/8650/1977/2113/4853/5595/6194/23533/4089/7249/5728/5170/57521/2114/1026/2549/5563/10000/7048"
"WP3674","Tgif disruption of Shh signaling",4,0.31068515497553,0.520553990113917,0.953947368421053,0.991532536782858,0.747935430558226,8455,"tags=100%, list=69%, signal=31%","60436/7050/2737/4087"
"WP521","Amino acid conjugation of benzoic acid",1,-0.520101117181766,-0.69709518171691,0.960076045627376,0.995450166514524,0.750890587319525,5887,"tags=100%, list=48%, signal=52%",""
"WP430","Statin Pathway",15,0.247713150522266,0.570326435355992,0.964376590330789,0.995450166514524,0.750890587319525,802,"tags=13%, list=7%, signal=12%","341/6713"
"WP4582","Cancer immunotherapy by CTLA4 blockade",12,-0.26858911980456,-0.537859825787435,0.965174129353234,0.995450166514524,0.750890587319525,3937,"tags=58%, list=32%, signal=40%","5781/5515/5295/5293/8503/3123/940"
"WP3891","Benzene metabolism",3,-0.325329253578636,-0.500950645681814,0.967307692307692,0.995450166514524,0.750890587319525,2384,"tags=67%, list=19%, signal=54%","2944/2052"
"WP696","Benzo(a)pyrene metabolism",7,0.274612598012953,0.529328422166618,0.967517401392111,0.995450166514524,0.750890587319525,3553,"tags=43%, list=29%, signal=30%","10327/1646/8644"
"WP2942","DDX1 as a regulatory component of the Drosha microprocessor",6,0.281477462071131,0.526725895569096,0.971238938053097,0.995450166514524,0.750890587319525,2590,"tags=33%, list=21%, signal=26%","29102/4683"
"WP2513","Nanoparticle triggered regulated necrosis",11,-0.256860765250472,-0.507331666086788,0.971900826446281,0.995450166514524,0.750890587319525,2885,"tags=36%, list=24%, signal=28%","7132/148022/5321/8737"
"WP4723","Omega-3/Omega-6 FA synthesis",11,-0.254117966060651,-0.501914299672901,0.973553719008264,0.995450166514524,0.750890587319525,2732,"tags=27%, list=22%, signal=21%","5321/10965/2182"
"WP3937","Microglia Pathogen Phagocytosis Pathway",36,0.219943316967631,0.626823025791755,0.977049180327869,0.995450166514524,0.750890587319525,2501,"tags=22%, list=20%, signal=18%","5881/54209/1535/5777/7410/10451/5296/10095"
"WP4532","Intraflagellar transport proteins binding to dynein",25,0.220962266218544,0.580568523902844,0.979411764705882,0.995450166514524,0.750890587319525,1053,"tags=8%, list=9%, signal=7%","89891/57560"
"WP692","Sulfation Biotransformation Reaction",6,-0.284059389786262,-0.490501497357131,0.98,0.995450166514524,0.750890587319525,8783,"tags=100%, list=72%, signal=28%","9061/6799/2936/6817/9060"
"WP80","Nucleotide GPCRs",8,0.236572618706787,0.469699224116321,0.983009708737864,0.995450166514524,0.750890587319525,2570,"tags=38%, list=21%, signal=30%","1241/5031/5029"
"WP4522","Metabolic pathway of LDL, HDL and TG, including diseases",9,-0.241517883499338,-0.460164683327411,0.984873949579832,0.995450166514524,0.750890587319525,3282,"tags=44%, list=27%, signal=33%","19/3931/4023/3949"
"WP4751","HIPK2 in kidney fibrosis",2,0.337302234545751,0.484995439085364,0.985971943887776,0.995450166514524,0.750890587319525,8128,"tags=100%, list=66%, signal=34%","6477/28996"
"WP697","Estrogen metabolism",9,0.217625458996328,0.44383266064857,0.987714987714988,0.995450166514524,0.750890587319525,9597,"tags=100%, list=78%, signal=22%","1728/54578/1312/2944/414/412/6817/1543/1545"
"WP325","Triacylglyceride Synthesis",14,-0.233795918367347,-0.481855624885714,0.988543371522095,0.995450166514524,0.750890587319525,9401,"tags=100%, list=77%, signal=23%","84649/55326/8694/8540/57678/56894/8443/2710/10554/57104/4023/3991/56895"
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway",43,0.211381552734483,0.629128198155817,0.989690721649485,0.995450166514524,0.750890587319525,2083,"tags=12%, list=17%, signal=10%","80347/23400/54676/26100/2475"
"WP4397","Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors",2,-0.315835186745099,-0.454271967058904,0.990059642147117,0.995450166514524,0.750890587319525,3197,"tags=100%, list=26%, signal=74%","692094"
"WP3845","Canonical and Non-canonical Notch signaling",22,0.200290610067453,0.513723357000406,0.994397759103641,0.997218358831711,0.752224374798003,1965,"tags=18%, list=16%, signal=15%","4237/102/4854/3280"
"WP623","Oxidative phosphorylation",37,-0.178982454914135,-0.455748830779194,0.997155049786629,0.997218358831711,0.752224374798003,4041,"tags=27%, list=33%, signal=18%","126328/4700/4716/4719/4697/4705/4717/4698/4714/4724"
"WP4324","Mitochondrial complex I assembly model OXPHOS system",45,-0.188459502891383,-0.49069893910195,0.997218358831711,0.997218358831711,0.752224374798003,4160,"tags=29%, list=34%, signal=19%","51103/55863/4700/4716/4719/4705/54968/4717/91942/29078/4698/4714/4724"
1 ID Description setSize enrichmentScore NES pvalue p.adjust qvalues rank leading_edge core_enrichment
2 WP3888 VEGFA-VEGFR2 Signaling Pathway 403 -0.462791684122784 -1.49292146323601 0.00104166666666667 0.0363875205254516 0.0274479301702532 2506 tags=29%, list=20%, signal=24% 6154/9209/2185/5867/301/468/6129/5970/2746/4673/2887/6595/1466/2022/6093/4641/23291/9444/3688/57758/9261/5784/4303/3142/9734/26058/6778/4855/5170/3791/8828/5578/6461/4773/10628/154796/4792/6648/4790/1432/25759/5803/2152/355/80031/3490/5587/8665/27289/5743/23189/4736/3725/51574/5908/152273/2549/6125/7414/5906/1397/2078/9252/4846/5563/11080/6886/6386/4772/22943/2308/56999/25/2534/6546/9365/781/3690/57326/154/1847/7220/4629/1839/9759/6401/5592/51309/1003/326624/6347/596/1465/1901/1827/32/10014/22899/114789/857/91624/84952/274/6722/4208/9079/1958/5579/7111/1960/9510/4929/57381/7148/10231/8013/81575/3164
3 WP4172 PI3K-Akt Signaling Pathway 252 -0.504934506863715 -1.58824388696871 0.00108813928182807 0.0363875205254516 0.0274479301702532 2187 tags=31%, list=18%, signal=26% 5728/9180/3716/55012/5170/57521/7424/3791/5578/3672/4254/1299/10161/3566/1436/7057/4790/1435/3574/3910/2323/10681/1026/7099/6446/4170/55970/3717/1975/7450/54331/4846/5563/284/7010/1291/4609/1288/5156/10000/3570/3690/4915/3913/3678/3563/5521/3680/90993/9586/5516/3815/1292/3082/3479/5525/80310/2260/3679/1286/627/596/1902/894/2690/10319/2258/3908/1440/2252/4804/2247/5649/2788/2791/8516/3569/7148
4 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway 243 -0.515280852572342 -1.61626208499425 0.00109409190371991 0.0363875205254516 0.0274479301702532 2187 tags=29%, list=18%, signal=24% 5728/9180/3716/55012/5170/57521/7424/3791/4254/2034/10161/3566/8660/1436/7057/51719/23216/1435/3910/81617/1026/55970/3717/1975/7450/54331/4846/5563/2308/284/7010/1288/5156/10000/3570/3690/3913/3678/3563/5521/3680/6515/90993/9586/5516/3815/1292/3082/3479/5525/80310/2260/3679/1286/1902/2690/10319/2258/10891/3908/1440/2252/4804/64344/2247/5649/2788/6517/2791/8516/7148
5 WP2882 Nuclear Receptors Meta-Pathway 222 -0.529042570431749 -1.64826733186755 0.00111607142857143 0.0363875205254516 0.0274479301702532 1655 tags=22%, list=13%, signal=19% 4240/8824/4780/60482/6594/5743/3725/5465/11214/34/2040/2308/4609/8850/5552/2908/2099/80315/3726/5244/6515/4616/1028/1066/1839/5243/330/3082/10486/23764/89795/6347/2258/10891/2289/1831/2042/2949/7049/5142/1958/6649/7048/3727/6517/10252/2878/5997/5166
6 WP382 MAPK Signaling Pathway 195 -0.581705105571315 -1.79816996071903 0.00112994350282486 0.0363875205254516 0.0274479301702532 1531 tags=23%, list=12%, signal=21% 355/1845/1844/4137/3725/5908/5602/55970/5906/9252/4772/775/7043/4609/10000/781/4915/6237/408/785/783/2260/1850/1326/5532/627/3306/9020/2316/8912/2258/2252/5533/6722/4208/120892/2247/10235/2353/8605/7048/2318/3727/1843/3164
7 WP306 Focal Adhesion 173 -0.563554095940283 -1.72444812849595 0.0011441647597254 0.0363875205254516 0.0274479301702532 2687 tags=40%, list=22%, signal=32% 5159/2268/858/387/2889/7409/9475/7423/3915/7408/6093/3688/1793/5728/394/5170/7424/83660/3791/5578/5500/3672/2909/7057/60/4659/25759/3910/23396/54776/87/3725/5908/5602/7414/5906/7450/7791/7094/1288/2534/3611/55742/5156/10000/3690/3913/3678/3680/1292/330/3082/3479/80310/3679/1286/596/894/2316/10319/3908/857/4660/10398/4638/5649/2318/5579/8516/7148
8 WP4223 Ras Signaling 142 -0.525682204537404 -1.5751526046082 0.00118906064209275 0.0363875205254516 0.0274479301702532 3203 tags=43%, list=26%, signal=32% 5293/2113/5601/5567/5595/5869/8503/22800/6655/805/83593/64926/5321/5159/81579/387/91860/51365/2324/808/5970/801/5900/4303/8831/22808/3791/5578/11186/1436/4790/25759/9846/8036/2114/10681/5908/5602/2549/55970/5906/54331/5336/7010/25/22821/5156/10000/4915/6237/3815/2260/10156/5320/23179/4804/10235/8605/5579/2788/2791
9 WP3929 Chemokine signaling pathway 124 -0.530461119643853 -1.57190665721361 0.00120918984280532 0.0363875205254516 0.0274479301702532 1891 tags=27%, list=15%, signal=23% 4792/7454/3702/7852/23236/4790/25759/6363/9547/10681/3579/2770/5908/55970/9844/3717/5906/108/54331/10000/6777/6366/408/2869/5332/6376/115/196883/6387/10235/5579/2788/2791/111
10 WP289 Myometrial Relaxation and Contraction Pathways 120 -0.711645314331361 -2.09559070147585 0.00121951219512195 0.0363875205254516 0.0274479301702532 1562 tags=40%, list=13%, signal=35% 3487/2114/5587/10681/3725/55970/108/3488/54331/4846/817/5336/6546/8787/10266/5996/6262/8786/800/408/489/58/2869/23764/10268/11142/5577/1902/467/5144/115/6263/3489/196883/59/10267/70/8490/5142/2353/3708/5579/2788/2791/111/5997/3569/1264
11 WP536 Calcium Regulation in the Cardiac Cell 107 -0.660848965792059 -1.92235988951507 0.00122699386503067 0.0363875205254516 0.0274479301702532 1596 tags=36%, list=13%, signal=32% 2767/844/5587/10681/2770/55970/108/54331/817/775/6546/8787/5996/6262/154/8786/2701/408/489/2781/2869/11142/5577/2775/115/6263/196883/309/57165/5350/8490/845/482/3708/5579/2788/2791/111/5997
12 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 100 -0.580112717768676 -1.67392091802786 0.00123456790123457 0.0363875205254516 0.0274479301702532 1241 tags=27%, list=10%, signal=24% 3725/34/23171/4204/6640/291/3570/4915/133522/6262/2908/6095/6844/5577/627/7259/6330/3757/10891/1390/6869/4208/1958/7434/11076/3569/5354
13 WP236 Adipogenesis 104 -0.613156949875672 -1.7724263819813 0.00123609394313968 0.0363875205254516 0.0274479301702532 2137 tags=41%, list=17%, signal=34% 6778/652/23175/1647/2034/183/6776/8660/81029/4000/355/1026/4205/3976/2487/5465/55847/2308/28999/4154/6777/2908/6095/4616/1052/1959/4692/3479/5914/25937/3977/1316/9021/5740/7025/3572/10891/4208/4209/1879/6517/3569/1675
14 WP35 G Protein Signaling Pathways 76 -0.679108269914708 -1.89534402071217 0.00131233595800525 0.0363875205254516 0.0274479301702532 1670 tags=39%, list=14%, signal=34% 11215/5153/2767/5587/10681/2770/55970/11214/108/9465/6237/2781/9630/9472/5577/27115/9590/5144/2775/115/196883/5533/2774/5142/5136/3708/5579/2788/2791/111
15 WP2355 Corticotropin-releasing hormone signaling pathway 73 -0.644471493229881 -1.78788402195755 0.00132450331125828 0.0363875205254516 0.0274479301702532 1683 tags=34%, list=14%, signal=30% 4790/1432/2767/10681/7099/2770/5908/4846/5563/8061/5336/6925/3726/408/2781/10411/596/2775/8912/2353/3727/5579/4929/2354/3164
16 WP2806 Human Complement System 63 -0.66087804735839 -1.79187590794092 0.00134228187919463 0.0363875205254516 0.0274479301702532 2111 tags=44%, list=17%, signal=37% 727/5578/1604/7454/7057/11326/3384/2219/5621/966/710/716/3690/3075/22918/5627/6401/715/718/6403/5806/2162/1634/5648/5199/730/2159/1675
17 WP455 GPCRs, Class A Rhodopsin-like 58 -0.639879635527298 -1.71711321066538 0.00135869565217391 0.0363875205254516 0.0274479301702532 2170 tags=38%, list=18%, signal=31% 4886/1131/10161/1240/7852/2857/23637/3579/6915/152/8477/5734/154/5733/1909/150/623/624/9934/5737/1910/185
18 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 56 -0.684700919154161 -1.82460654198067 0.00137741046831956 0.0363875205254516 0.0274479301702532 1778 tags=39%, list=14%, signal=34% 83439/60/2010/4000/87/6443/775/6546/6444/781/3690/6262/3678/3680/785/783/3679/1756/3908/1674/8516/6442
19 WP2849 Hematopoietic Stem Cell Differentiation 43 -0.67034141801554 -1.73583915337319 0.00140646976090014 0.0363875205254516 0.0274479301702532 2112 tags=47%, list=17%, signal=39% 4005/4254/79366/4773/6776/7852/1435/10320/399/3690/2313/3071/863/3757/1440/2353/947/3569/7148/2354
20 WP558 Complement and Coagulation Cascades 39 -0.745125593798936 -1.90284177138585 0.00142247510668563 0.0363875205254516 0.0274479301702532 1220 tags=38%, list=10%, signal=35% 7450/710/716/3075/7035/5627/2157/715/718/623/1191/5648/730/2159/1675
21 WP98 Prostaglandin Synthesis and Regulation 37 -0.761060835875943 -1.93791389367576 0.00142247510668563 0.0363875205254516 0.0274479301702532 1600 tags=46%, list=13%, signal=40% 308/3290/3248/5743/6915/5734/133522/5733/4286/1909/5740/10891/5730/309/5737/1910/5742
22 WP4149 White fat cell differentiation 30 -0.734621214684463 -1.78520995103201 0.00151745068285281 0.0363875205254516 0.0274479301702532 1825 tags=50%, list=15%, signal=43% 6776/83439/3662/23090/2308/28999/6777/2908/6095/1052/1959/5914/9314/1879/10365
23 WP383 Striated Muscle Contraction Pathway 23 -0.821283572235296 -1.90691582895276 0.00152439024390244 0.0363875205254516 0.0274479301702532 698 tags=52%, list=6%, signal=49% 7139/58/7431/7168/1756/7169/59/10398/70/8736/7111/1674
24 WP170 Nuclear Receptors 29 -0.793339860748143 -1.91111582812928 0.00153139356814701 0.0363875205254516 0.0274479301702532 1314 tags=41%, list=11%, signal=37% 2494/5465/2908/6095/2099/7067/5914/4919/7025/5241/4929/3164
25 WP3893 Development and heterogeneity of the ILC family 18 -0.803262668097291 -1.74375797527922 0.0016 0.0363875205254516 0.0274479301702532 1621 tags=56%, list=13%, signal=48% 3574/4783/374/9760/6095/3398/85480/90865/7704/3569
26 WP545 Complement Activation 15 -0.852488029806488 -1.78174120099361 0.00164203612479475 0.0363875205254516 0.0274479301702532 973 tags=47%, list=8%, signal=43% 716/715/718/5648/5199/730/1675
27 WP2366 Butyrate-induced histone acetylation 2 0.99245902741194 1.42702316343119 0.00200400801603206 0.0427007861877601 0.0322101693265073 49 tags=50%, list=0%, signal=50% 47
28 WP481 Insulin Signaling 150 -0.506173983161364 -1.52215372656681 0.00235571260306243 0.046028580923895 0.0347204002029001 1784 tags=20%, list=15%, signal=17% 8660/10938/1432/2992/3799/25759/6446/3725/5602/2549/5167/9252/5563/6812/2308/4215/1326/6844/9021/6236/9020/6196/30846/6722/1958/2353/10580/5579/6517/57381
29 WP3594 Circadian rhythm related genes 138 -0.514116761839872 -1.53463022711246 0.00239520958083832 0.046028580923895 0.0347204002029001 1718 tags=24%, list=14%, signal=21% 23373/7316/2767/355/114781/6500/3725/26224/5602/4783/5465/5563/7071/1471/6095/3398/3400/8863/23411/9099/3778/10891/1390/5730/4804/8864/1958/1408/3727/1960/3569/687/5187
30 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition 15 0.817074347545397 1.88120452658206 0.00254452926208651 0.046028580923895 0.0347204002029001 675 tags=53%, list=6%, signal=50% 991/699/701/1062/4085/9700/9232/9184
31 WP2328 Allograft Rejection 62 -0.611695546067999 -1.65863873075632 0.00267022696929239 0.046028580923895 0.0347204002029001 2744 tags=37%, list=22%, signal=29% 3123/3127/3113/712/3115/3111/3108/842/727/1604/940/6363/355/5156/6366/5243/7431/718/6387/120892/185/730/23743
32 WP531 DNA Mismatch Repair 21 0.843167010261677 2.13563192725278 0.00272479564032698 0.046028580923895 0.0347204002029001 1385 tags=62%, list=11%, signal=55% 5424/5985/9156/4436/5984/3978/5111/5982/6119/5983/2956/5395/5425
33 WP2361 Gastric Cancer Network 1 22 0.881905616185124 2.26199078205191 0.00280112044817927 0.046028580923895 0.0347204002029001 360 tags=68%, list=3%, signal=66% 6790/1063/11065/56992/7153/4605/22974/144455/86/1894/4173/57122/9585/8607/286826
34 WP2363 Gastric Cancer Network 2 29 0.759734189615142 2.08343199470384 0.00286532951289398 0.046028580923895 0.0347204002029001 613 tags=38%, list=5%, signal=36% 55215/63922/11065/7153/29089/5984/29028/84823/27101/5983/79075
35 WP4752 Base Excision Repair 30 0.781189558713735 2.14866418678642 0.00291545189504373 0.046028580923895 0.0347204002029001 1470 tags=50%, list=12%, signal=44% 5424/23583/2237/5427/3978/5426/5111/7374/4595/10038/11284/6996/27301/5425/328
36 WP4222 Phosphodiesterases in neuronal function 31 -0.72750945670304 -1.77849793999341 0.00303030303030303 0.046028580923895 0.0347204002029001 1607 tags=45%, list=13%, signal=39% 5153/5139/108/5140/27115/84152/5144/115/196883/8654/5142/5136/5138/111
37 WP2516 ATM Signaling Pathway 37 0.722976864053179 2.07909842918551 0.00334448160535117 0.046028580923895 0.0347204002029001 886 tags=38%, list=7%, signal=35% 835/898/995/672/891/5888/983/993/1111/637/2177/1017/11200/5883
38 WP4290 Metabolic reprogramming in colon cancer 39 0.650339438615221 1.89824335654321 0.00334448160535117 0.046028580923895 0.0347204002029001 2135 tags=41%, list=17%, signal=34% 5831/47/6472/2194/10606/2023/5471/2618/5723/22934/29968/5226/5230/2597/2821/9123
39 WP4754 IL-18 signaling pathway 222 -0.46719058505988 -1.4555633556707 0.00334821428571429 0.046028580923895 0.0347204002029001 2192 tags=29%, list=18%, signal=24% 80149/5728/8698/57521/5834/5578/4254/3831/51222/4792/948/1938/8153/81618/7128/4790/7052/379/5803/56257/6363/8837/355/51341/80031/84818/770/8870/5743/3725/64332/4205/7185/22821/7078/83931/10194/7832/1112/51299/4776/58/330/11096/9208/2920/975/6347/26353/596/9021/467/10418/5806/3757/32/6869/274/59/2353/5579/1674/3569/10365/3164
40 WP466 DNA Replication 41 0.846456079198003 2.49474634065957 0.00341296928327645 0.046028580923895 0.0347204002029001 1428 tags=76%, list=12%, signal=67% 4998/5424/4171/5985/990/8318/8317/55388/23594/81620/4173/10926/5427/5984/5426/5111/5982/6119/1017/5558/5557/23649/4176/5983/4175/4174/5001/4172/51053/5425/4999
41 WP1971 Integrated Cancer Pathway 43 0.653015909410761 1.94355049974829 0.00343642611683849 0.046028580923895 0.0347204002029001 854 tags=33%, list=7%, signal=30% 641/672/5347/983/4436/993/1111/1869/5451/1017/1019/4312/11200/2956
42 WP4753 Nucleotide Excision Repair 43 0.666293811275025 1.98306909712394 0.00343642611683849 0.046028580923895 0.0347204002029001 498 tags=23%, list=4%, signal=22% 5424/5985/5427/5984/3978/5426/5111/5982/6119/5983
43 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM 52 0.654701382215583 2.0441135050262 0.00354609929078014 0.046028580923895 0.0347204002029001 1429 tags=37%, list=12%, signal=32% 1020/9156/641/995/672/5888/86/675/1111/1869/637/2177/5111/11200/5591/5883/317/581/10155
44 WP45 G1 to S cell cycle control 61 0.685587337829529 2.1995751010812 0.00374531835205993 0.046028580923895 0.0347204002029001 1428 tags=49%, list=12%, signal=44% 4998/898/4171/8318/9134/891/23594/983/4173/993/5427/1869/5426/5111/6119/1017/5558/5557/23649/1870/1019/4176/7027/4175/4174/1871/5001/4172/148327/4999
45 WP183 Proteasome Degradation 58 0.515932034207858 1.63483847206574 0.0037593984962406 0.046028580923895 0.0347204002029001 2480 tags=41%, list=20%, signal=33% 5709/5690/6185/5717/6184/5691/5693/5688/5692/5708/5685/5686/5721/5714/7321/5687/5718/5683/5706/5704/5710/10197/7317/5695
46 WP2431 Spinal Cord Injury 90 -0.572440468952739 -1.63236239454608 0.00377833753148615 0.046028580923895 0.0347204002029001 1199 tags=27%, list=10%, signal=24% 7099/5743/56963/4609/1464/7832/9423/7431/2920/6347/627/6403/5320/9353/388/6869/4804/1958/2353/358/6586/7538/3569/3164
47 WP707 DNA Damage Response 62 0.63345814777894 2.02657439950036 0.00395256916996047 0.046028580923895 0.0347204002029001 886 tags=31%, list=7%, signal=29% 1020/898/995/672/9134/9133/891/5888/983/993/1111/1869/637/2177/1017/1019/11200/5591/5883
48 WP1530 miRNA Regulation of DNA Damage Response 64 0.63560810177656 2.02952026239957 0.00401606425702811 0.046028580923895 0.0347204002029001 886 tags=31%, list=7%, signal=29% 1020/898/995/672/9134/9133/891/5888/983/993/1111/1869/637/2177/1017/1019/4176/11200/5591/5883
49 WP4016 DNA IR-damage and cellular response via ATR 75 0.760155956927704 2.53170925712447 0.00413223140495868 0.046028580923895 0.0347204002029001 1131 tags=43%, list=9%, signal=39% 2305/55215/63967/4171/9156/8318/995/2175/672/5347/5888/83990/983/675/4436/1111/2237/55159/1869/2177/5111/1196/1017/79728/80010/11073/11200/5591/55775/5883/9521/9937
50 WP410 Exercise-induced Circadian Regulation 44 -0.639139699850929 -1.66231682685446 0.00418410041841004 0.046028580923895 0.0347204002029001 1205 tags=23%, list=10%, signal=21% 50486/5813/5516/11030/2674/8864/1408/7122/687/5187
51 WP1541 Energy Metabolism 42 -0.64632675153625 -1.66464566680558 0.00422535211267606 0.046028580923895 0.0347204002029001 1322 tags=31%, list=11%, signal=28% 1432/4205/5465/5563/2308/133522/51422/5532/23411/10891/5533/4208/4209
52 WP4022 Pyrimidine metabolism 79 0.591516775875115 1.97457796170619 0.00423728813559322 0.046028580923895 0.0347204002029001 1906 tags=35%, list=16%, signal=30% 5424/4830/7083/5427/6241/5437/5426/5558/1841/790/5557/7298/54963/23649/87178/5436/7371/5433/84172/10201/1890/79077/129607/5425/25885/5422/7372/5439
53 WP1528 Physiological and Pathological Hypertrophy of the Heart 24 -0.720931513879714 -1.69304310836266 0.00451807228915663 0.0481348470806302 0.0363092044290522 2941 tags=79%, list=24%, signal=60% 6774/5606/805/5581/5530/387/1489/801/183/50804/1432/3725/817/4776/3977/5532/3572/2353/5579
54 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) 21 -0.764734878027421 -1.72266026175418 0.0047244094488189 0.0493233618233618 0.0372057279952017 1433 tags=38%, list=12%, signal=34% 3248/5743/6915/5740/5730/5737/8309/5742
55 WP2446 Retinoblastoma Gene in Cancer 86 0.778790413293543 2.60647947921743 0.00480769230769231 0.0493233618233618 0.0372057279952017 854 tags=50%, list=7%, signal=47% 24137/4998/898/5985/7272/7153/8318/8317/9134/9133/891/2189/81620/983/4173/10733/993/6502/890/1111/54443/5427/6241/1869/5984/1786/5426/5111/6119/1017/3925/5557/7298/1870/1019/4176/5983/7027/10592/4175/5928/5591/2956
56 WP179 Cell Cycle 115 0.67352923441135 2.39594113780755 0.00546448087431694 0.0546566692975533 0.0412287625140199 779 tags=36%, list=6%, signal=34% 4998/898/4171/7272/990/8318/8317/991/995/5347/699/9134/9133/891/23594/983/9088/4173/10926/993/6502/890/1111/5933/1869/9700/5111/9232/1017/1870/3066/1019/4176/7027/10459/4175/9184/2932/11200/4174/5591
57 WP411 mRNA Processing 122 0.492406310910327 1.76034403509172 0.00552486187845304 0.0546566692975533 0.0412287625140199 2226 tags=34%, list=18%, signal=28% 51692/9343/6628/6632/1196/3191/5496/6636/6635/10772/6637/5725/56339/29894/6626/1478/4841/55660/51690/6627/1659/11338/9410/53981/6625/8683/10236/57819/3181/10898/6634/6426/1477/8106/1479/23450/8175/6629/8449/3276/6633/1660
58 WP408 Oxidative Stress 29 -0.705190779022085 -1.69876912319646 0.00612557427258806 0.0595362832809435 0.0449095657657887 1847 tags=34%, list=15%, signal=29% 6648/4790/1432/4780/5602/3726/4784/2353/6649/2878
59 WP1984 Integrated Breast Cancer Pathway 143 0.412990391457822 1.49046424149869 0.00625 0.059698275862069 0.0450317604355717 854 tags=16%, list=7%, signal=15% 6790/8438/641/79902/672/5347/5888/26284/675/4436/993/1111/7517/1869/637/1017/1019/6597/4312/55526/27005/11200/2956
60 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 17 -0.775809358119203 -1.66309595715165 0.00644122383252818 0.0602785434498767 0.0454694694083242 1404 tags=47%, list=11%, signal=42% 87/3725/7414/3690/4026/8076/4638/3708
61 WP554 ACE Inhibitor Pathway 11 -0.85530951024262 -1.68934168839734 0.00661157024793388 0.0602785434498767 0.0454694694083242 308 tags=55%, list=3%, signal=53% 4846/623/624/4306/185/1511
62 WP2338 miRNA Biogenesis 6 0.879053726567659 1.64496424677402 0.00663716814159292 0.0602785434498767 0.0454694694083242 571 tags=50%, list=5%, signal=48% 6895/57510/5901
63 WP2276 Glial Cell Differentiation 5 -0.920932317124545 -1.55415561317042 0.0072992700729927 0.0636867012817811 0.0480403199864471 77 tags=80%, list=1%, signal=80% 4155/4478/11076/5354
64 WP1591 Heart Development 30 -0.681766389246273 -1.65676694061222 0.00758725341426404 0.0636867012817811 0.0480403199864471 2090 tags=53%, list=17%, signal=44% 4089/650/7423/652/7424/4773/23493/657/5308/6910/4772/4776/9464/2627/6722/4208
65 WP1600 Nicotine Metabolism 1 -0.995107233140341 -1.33374921644582 0.00760456273764259 0.0636867012817811 0.0480403199864471 62 tags=100%, list=1%, signal=100%
66 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity 14 0.758935770206651 1.72082838746272 0.00767263427109974 0.0636867012817811 0.0480403199864471 487 tags=21%, list=4%, signal=21% 6659/1869/1019
67 WP3298 Melatonin metabolism and effects 26 -0.695722684462236 -1.6436047371393 0.00769230769230769 0.0636867012817811 0.0480403199864471 542 tags=23%, list=4%, signal=22% 2308/8863/23411/8864/1408/5187
68 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 82 -0.560787242557001 -1.58608821561989 0.00770218228498074 0.0636867012817811 0.0480403199864471 3220 tags=43%, list=26%, signal=32% 7189/3601/5601/5595/915/7040/3937/916/9051/7409/2185/8915/5970/920/10019/5170/4773/4792/7454/940/3702/4790/1432/9846/355/3662/3725/4772/2534/7431/1326/9020/2353/3708/3569
69 WP24 Peptide GPCRs 21 -0.72515909137611 -1.63351088861753 0.0078740157480315 0.0641500694766095 0.0483898491016796 1762 tags=52%, list=14%, signal=45% 728/4886/7852/10396/3579/1909/623/6869/624/1910/185
70 WP4589 Major receptors targeted by epinephrine and norepinephrine 11 -0.832489389521898 -1.64426913769363 0.00826446280991736 0.0655698899278021 0.0494608517980951 1354 tags=64%, list=11%, signal=57% 152/108/154/150/115/196883/111
71 WP474 Endochondral Ossification 54 -0.605621683222306 -1.60708674739698 0.00829875518672199 0.0655698899278021 0.0494608517980951 1766 tags=41%, list=14%, signal=35% 55553/51719/657/5727/4921/2487/5167/9507/7078/6777/1028/9759/3479/7067/11096/2260/2690/4256/4208/2247/5745/9510
72 WP4352 Ciliary landscape 197 0.362614716331557 1.39055119188859 0.00840336134453781 0.0655698899278021 0.0494608517980951 2047 tags=20%, list=17%, signal=17% 128239/4171/9343/55388/4173/4436/84515/25804/10238/3066/4176/79989/10051/4175/89891/4174/25904/54512/57560/150737/4172/116225/4704/7022/5714/100616408/284086/63929/7020/2717/57414/5718/54903/11018/90410/5706/6629/5704/100616387
73 WP2525 Trans-sulfuration and one carbon metabolism 28 0.618571121288761 1.68827533226606 0.00864553314121038 0.0665225744476465 0.0501794832903585 1790 tags=46%, list=15%, signal=40% 6472/25902/1786/1789/7298/191/1788/5723/4522/29968/10797/2730/1719
74 WP3527 Preimplantation Embryo 31 -0.666639128694346 -1.62969196644526 0.00909090909090909 0.0678565179352581 0.0511857070497767 228 tags=26%, list=2%, signal=25% 5087/83439/3662/9314/4306/1958/7538/2354
75 WP2406 Cardiac Progenitor Differentiation 30 -0.667798781954949 -1.62282412623367 0.00910470409711684 0.0678565179352581 0.0511857070497767 1210 tags=53%, list=10%, signal=48% 652/3791/7852/1432/6910/22943/4920/5156/3815/7139/3479/70/4208/2247/4684/64321
76 WP1544 MicroRNAs in cardiomyocyte hypertrophy 76 -0.564283495089114 -1.57487604817129 0.00918635170603675 0.0678565179352581 0.0511857070497767 2402 tags=46%, list=20%, signal=37% 6774/5293/5606/5595/8503/5330/805/7040/5530/387/9475/1489/6093/801/9734/5170/183/50804/4790/1432/3976/817/4776/9759/3479/5592/5532/9020/5320/3572/1827/10014/2247/4638/5579
77 WP167 Eicosanoid Synthesis 18 -0.747061129454138 -1.62175320009889 0.0096 0.0698524776194679 0.0526913046075029 458 tags=33%, list=4%, signal=32% 5743/5740/5320/5730/4056/5742
78 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS 16 -0.762435441713953 -1.61661376948339 0.00970873786407767 0.0698524776194679 0.0526913046075029 658 tags=69%, list=5%, signal=65% 4155/650/2736/652/55553/3976/3479/2920/2247/6663/5354
79 WP428 Wnt Signaling 93 -0.516013726346037 -1.47939174505811 0.0099626400996264 0.0707602899383721 0.0533760879831536 1778 tags=28%, list=14%, signal=24% 83439/81029/6423/23236/3725/85407/817/5176/4772/8061/22943/23500/4609/4920/4776/5332/5532/4919/7482/8324/894/5533/6422/166336/5579/64321
80 WP465 Tryptophan metabolism 27 -0.673088908977646 -1.6060772897894 0.0107197549770291 0.0744766660265028 0.0561794345668281 796 tags=37%, list=6%, signal=35% 223/4967/8854/216/38/4129/11185/217/316/23498
81 WP334 GPCRs, Class B Secretin-like 4 -0.926494114951996 -1.50086921601437 0.0109689213893967 0.0744766660265028 0.0561794345668281 135 tags=75%, list=1%, signal=74% 10203/5745/7434
82 WP2858 Ectoderm Differentiation 112 -0.512859193219582 -1.49738516820973 0.0109756097560976 0.0744766660265028 0.0561794345668281 2546 tags=39%, list=21%, signal=31% 5236/1004/4926/51762/79776/54521/5292/10257/5362/652/51222/83439/657/345557/50937/1896/5452/6907/23229/6622/56963/4204/6781/6386/4772/4609/4920/2534/8835/10253/8322/5010/91653/51422/79658/10486/55843/6347/1756/8848/2627/9079/7704/114815
83 WP4482 Vitamin D in inflammatory diseases 21 -0.697303771819546 -1.57076332281756 0.0110236220472441 0.0744766660265028 0.0561794345668281 1891 tags=48%, list=15%, signal=40% 5530/4089/5970/4792/4790/1432/4772/2908/3569/1843
84 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome 22 0.683736816044692 1.75370963384132 0.0112044817927171 0.0747865411224731 0.0564131803640924 2889 tags=55%, list=24%, signal=42% 11335/23028/1869/3066/5928/6839/6720/9219/57504/10951/9112/51176
85 WP247 Small Ligand GPCRs 10 -0.821064222173243 -1.58944551939811 0.0118043844856661 0.0778527262507026 0.0587260731931008 1626 tags=90%, list=13%, signal=78% 8698/1903/6915/9294/5734/5733/1902/1901/5737
86 WP2795 Cardiac Hypertrophic Response 51 -0.582834347182136 -1.53056492528391 0.0125523012552301 0.0818114693576175 0.061712242703732 2310 tags=33%, list=19%, signal=27% 801/9734/5170/5578/4773/4790/1432/5587/4205/817/9759/3479/5592/9020/5320/10014/2247
87 WP2895 Differentiation of white and brown adipocyte 18 -0.723465431235367 -1.57053061926027 0.0128 0.0824558139534884 0.0621982864137087 1182 tags=56%, list=10%, signal=50% 655/650/652/23090/63976/133522/253738/4093/10891/27129
88 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 9 -0.852789090889178 -1.62482138493552 0.0134453781512605 0.0854001096190737 0.0644192352627252 1322 tags=89%, list=11%, signal=79% 4205/817/894/6722/9314/4208/4209/93649
89 WP3878 ATM Signaling Network in Development and Disease 41 0.549013693025727 1.61809919652966 0.0136518771331058 0.0854001096190737 0.0644192352627252 779 tags=20%, list=6%, signal=18% 1020/699/983/9212/1111/3150/11200/5591
90 WP2197 Endothelin Pathways 23 -0.671337050093026 -1.55875910667561 0.013719512195122 0.0854001096190737 0.0644192352627252 2310 tags=52%, list=19%, signal=42% 801/4886/5578/23236/10681/2770/4846/1909/10267/4638/1910/1264
91 WP49 IL-2 Signaling Pathway 41 -0.603580080557865 -1.55468156464178 0.0141043723554302 0.0868202476100925 0.0654904774866173 1825 tags=29%, list=15%, signal=25% 3716/6776/9846/4137/3725/4609/2534/6777/596/9021/894/2353
92 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 23 -0.668402451934719 -1.55194534359928 0.0152439024390244 0.0928035379254891 0.0700038087714596 395 tags=35%, list=3%, signal=34% 2200/4052/2022/1432/2316/7049/7048/185
93 WP185 Integrin-mediated Cell Adhesion 87 -0.520619938572016 -1.48375056211518 0.0163316582914573 0.098344985798558 0.0741838483033014 2709 tags=33%, list=22%, signal=26% 3684/858/2889/3683/9475/7408/825/6093/3688/1793/5170/3672/5908/5602/7414/5906/7791/7094/2534/3611/10000/3690/3678/3680/3679/7145/857/10580/8516
94 WP4481 Resistin as a regulator of inflammation 28 -0.655231246365445 -1.57139210846378 0.016793893129771 0.10004104079455 0.0754632209679579 1891 tags=39%, list=15%, signal=33% 4792/23236/113026/4790/1432/5336/10000/5332/84812/3708/3569
95 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 11 -0.794035539572439 -1.56831804511128 0.0181818181818182 0.10715667311412 0.0808307034510842 1121 tags=45%, list=9%, signal=41% 22943/2308/4093/1634/6422
96 WP3599 Transcription factor regulation in adipogenesis 19 -0.689736241592773 -1.52221495678199 0.0188679245283019 0.10743374272786 0.081039703330725 1104 tags=42%, list=9%, signal=38% 23175/8660/2308/2908/1052/10891/6517/3569
97 WP4249 Hedgehog Signaling Pathway 34 -0.613979531009327 -1.52772199875654 0.0194319880418535 0.10743374272786 0.081039703330725 1663 tags=59%, list=14%, signal=51% 1453/5567/51684/1452/2619/2736/374654/5727/50937/2121/2735/64839/132884/8643/8405/8452/408/91653/596/894
98 WP516 Hypertrophy Model 15 -0.733841554420393 -1.53376433075407 0.0197044334975369 0.10743374272786 0.081039703330725 1051 tags=40%, list=9%, signal=37% 9948/1839/6935/467/3727/8013
99 WP3624 Lung fibrosis 42 -0.595090254201187 -1.53268360107275 0.0197183098591549 0.10743374272786 0.081039703330725 1198 tags=33%, list=10%, signal=30% 4502/4780/4204/4092/2006/3082/3479/2920/6347/5806/1440/2252/2247/3569
100 WP4204 Tumor suppressor activity of SMARCB1 26 0.611731763503002 1.63934021100858 0.0198863636363636 0.10743374272786 0.081039703330725 1153 tags=35%, list=9%, signal=31% 86/2146/1019/6597/6598/5928/6602/6603/23512
101 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) 12 -0.780021355445463 -1.56202213498319 0.0199004975124378 0.10743374272786 0.081039703330725 1825 tags=58%, list=15%, signal=50% 6776/374/8061/4609/2099/7431/5241
102 WP2029 Cell Differentiation - Index 6 -0.881008856885747 -1.52128807927282 0.02 0.10743374272786 0.081039703330725 366 tags=83%, list=3%, signal=81% 4205/10014/6722/4208/4209
103 WP4284 Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer 2 0.969356206570633 1.39380440117446 0.0200400801603206 0.10743374272786 0.081039703330725 117 tags=50%, list=1%, signal=50% 9134
104 WP2911 miRNA targets in ECM and membrane receptors 22 -0.670621722009888 -1.53460715356793 0.0201550387596899 0.10743374272786 0.081039703330725 2366 tags=41%, list=19%, signal=33% 3915/3672/7057/3910/1291/3913/1292/6383/7148
105 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 9 -0.821314343290443 -1.56485246233761 0.0201680672268908 0.10743374272786 0.081039703330725 1720 tags=67%, list=14%, signal=57% 23236/2770/6262/7220/6263/3708
106 WP4521 Glycosylation and related congenital defects 25 0.625791964921431 1.6442405464169 0.0205882352941176 0.107777907474417 0.0812993145873906 3238 tags=56%, list=26%, signal=41% 7841/10195/79053/8818/29929/79644/8813/5373/1798/9526/4247/22845/54344/79087
107 WP4540 Pathways Regulating Hippo Signaling 80 -0.514765914067745 -1.45131657449357 0.02088772845953 0.107777907474417 0.0812993145873906 2054 tags=36%, list=17%, signal=30% 5159/387/2771/1004/2324/5573/3791/5578/83439/1436/23236/2767/7005/1012/5563/7003/7010/5156/4915/3815/51422/2260/26524/5332/1003/5577/4804/2774/5579
108 WP404 Nucleotide Metabolism 18 0.676170913550093 1.62381396176178 0.0212201591511936 0.107777907474417 0.0812993145873906 3354 tags=61%, list=27%, signal=44% 5424/6241/3251/10797/1719/5422/6723/4831/5423/3614/6240
109 WP3591 Sleep regulation 13 -0.762190632381489 -1.54820277261946 0.021630615640599 0.107777907474417 0.0812993145873906 1424 tags=46%, list=12%, signal=41% 114781/1471/8863/5730/2353/3569
110 WP4493 Cells and Molecules involved in local acute inflammatory response 13 -0.763202044338344 -1.5502572072049 0.021630615640599 0.107777907474417 0.0812993145873906 531 tags=69%, list=4%, signal=66% 3683/3688/6404/727/7412/718/6403/730/3569
111 WP3931 ESC Pluripotency Pathways 83 -0.513192199879881 -1.45271763765166 0.021656050955414 0.107777907474417 0.0812993145873906 1374 tags=23%, list=11%, signal=20% 81029/657/3725/2549/3976/4092/5156/10000/8322/4093/2260/3977/7482/8324/3572/2258/2252/2247/2353
112 WP366 TGF-beta Signaling Pathway 128 -0.468666885625339 -1.39109929248597 0.0216867469879518 0.107777907474417 0.0812993145873906 1465 tags=17%, list=12%, signal=15% 1026/6500/3725/4205/7071/4092/4609/3690/3726/10413/7041/6935/1316/467/9839/857/4208/7049/2353/7048/3727/2354
113 WP4659 Gastrin Signaling Pathway 105 -0.485368268009291 -1.40931408025564 0.02203182374541 0.107777907474417 0.0812993145873906 2080 tags=27%, list=17%, signal=22% 5970/6093/3688/960/5578/4792/10524/8649/4790/1432/5587/1026/5743/3725/3717/2308/4609/2534/6925/408/3815/330/388/9314/4208/1958/2353/4209
114 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) 56 -0.552922911614378 -1.47344151807024 0.0220385674931129 0.107777907474417 0.0812993145873906 1683 tags=50%, list=14%, signal=43% 55806/4089/2619/10468/2736/864/26018/1523/652/4254/4790/27122/657/3516/3725/3488/4772/22943/6925/2908/1959/4345/3479/4487/2353/947/6422/2354
115 WP2884 NRF2 pathway 96 -0.50229588517062 -1.43999197856862 0.0225 0.107777907474417 0.0812993145873906 787 tags=14%, list=6%, signal=13% 6515/1066/1839/3082/23764/2258/2042/2949/1958/6649/7048/6517/2878
116 WP186 Homologous recombination 12 0.753764556637835 1.65493057410169 0.0225563909774436 0.107777907474417 0.0812993145873906 522 tags=33%, list=4%, signal=32% 5424/5888/675/25788
117 WP3413 NOTCH1 regulation of human endothelial cell calcification 16 -0.719108393262633 -1.52474618399967 0.0226537216828479 0.107777907474417 0.0812993145873906 2245 tags=38%, list=18%, signal=31% 28514/2702/3672/55553/1902/4256
118 WP1533 Vitamin B12 Metabolism 30 -0.628971424933689 -1.52846939927905 0.0227617602427921 0.107777907474417 0.0812993145873906 1854 tags=37%, list=15%, signal=31% 3043/6648/4790/3039/3949/6948/4524/6347/12/6649/3569
119 WP241 One Carbon Metabolism 25 0.608137785972 1.59785497665971 0.0235294117647059 0.110468594217348 0.0833289604869602 961 tags=36%, list=8%, signal=33% 6472/25902/1786/1789/7298/2618/191/1788/4522
120 WP4756 Renin Angiotensin Aldosterone System (RAAS) 28 -0.642313201374039 -1.54041172700475 0.0244274809160305 0.113215258855586 0.0854008317797218 2977 tags=57%, list=24%, signal=43% 5330/805/10488/1636/91860/468/808/801/183/8536/817/90993/9586/3708/185/1511
121 WP304 Kit receptor signaling pathway 59 -0.547763539132581 -1.46610882741393 0.0245231607629428 0.113215258855586 0.0854008317797218 2042 tags=42%, list=17%, signal=35% 6774/2309/5595/6194/7006/3635/7409/6615/2887/5578/4254/6776/1432/9846/4137/3717/695/2534/6777/3726/4286/3815/596/2353/5579
122 WP4496 Signal transduction through IL1R 30 -0.61959163714888 -1.5056754884073 0.0257966616084977 0.118110334967833 0.0890932984651901 2594 tags=47%, list=21%, signal=37% 7189/5606/7040/7042/5970/54472/4792/4790/1432/3725/7043/11213/9020/3569
123 WP2023 Cell Differentiation - Index expanded 11 -0.778736061181117 -1.53809968982857 0.0264462809917355 0.120092128437881 0.0905882101269975 688 tags=64%, list=6%, signal=60% 4205/3398/10014/6722/9314/4208/4209
124 WP4191 Caloric restriction and aging 8 -0.836380477237547 -1.55342529938321 0.0271186440677966 0.122144136695604 0.0921360863920861 658 tags=38%, list=5%, signal=36% 3479/23411/10891
125 WP2848 Differentiation Pathway 26 -0.627651287352175 -1.48278998543939 0.0276923076923077 0.123722084367246 0.0933263680292543 2090 tags=58%, list=17%, signal=48% 652/4254/1436/1435/2323/22943/7043/4907/3570/3815/3082/3479/7482/2247/3569
126 WP1539 Angiogenesis 24 -0.646934398249501 -1.51926750798385 0.0286144578313253 0.124077782462057 0.0935946791515044 2054 tags=38%, list=17%, signal=31% 3791/1432/7077/4846/284/7010/7078/5156/2247
127 WP1992 Genes targeted by miRNAs in adipocytes 10 -0.782703487687222 -1.51518543607815 0.0286677908937605 0.124077782462057 0.0935946791515044 1235 tags=70%, list=10%, signal=63% 3784/58155/2078/9759/3479/9464/6722
128 WP2855 Dopaminergic Neurogenesis 10 -0.782640519459834 -1.515063539929 0.0286677908937605 0.124077782462057 0.0935946791515044 1529 tags=60%, list=12%, signal=53% 216/2735/6571/1028/4487/4929
129 WP3892 Development of pulmonary dendritic cells and macrophage subsets 10 -0.78684563200572 -1.52320394735892 0.0286677908937605 0.124077782462057 0.0935946791515044 1654 tags=70%, list=13%, signal=61% 1435/10320/2323/3662/3394/6925/3398
130 WP3299 let-7 inhibition of ES cell reprogramming 5 -0.870618600337099 -1.46924671822705 0.0291970802919708 0.125389011486448 0.0945837688772942 1060 tags=60%, list=9%, signal=55% 4609/9314/1958
131 WP3287 Overview of nanoparticle effects 15 -0.713421200746702 -1.49108480423036 0.0295566502463054 0.125907407654978 0.094974806838355 1407 tags=33%, list=11%, signal=30% 5743/10000/596/5742/3569
132 WP3947 Serotonin and anxiety 7 -0.851912216031474 -1.51661298422642 0.0297723292469352 0.125907407654978 0.094974806838355 435 tags=57%, list=4%, signal=55% 5341/84812/2353/5579
133 WP2881 Estrogen Receptor Pathway 10 -0.781205151773883 -1.51228490376935 0.03035413153457 0.127395370228423 0.0960972106796195 1374 tags=40%, list=11%, signal=36% 3725/5465/2099/5166
134 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) 11 -0.764891615812808 -1.51075520408002 0.031404958677686 0.129485796476088 0.0976740665039081 1060 tags=45%, list=9%, signal=42% 7040/3688/4609/9839/6422
135 WP477 Cytoplasmic Ribosomal Proteins 85 -0.501189342497575 -1.42462469075787 0.0314465408805031 0.129485796476088 0.0976740665039081 3956 tags=54%, list=32%, signal=37% 6135/9349/6235/6205/6152/7311/6233/6217/6202/6157/9045/6130/6137/6176/6194/6181/23521/6229/6192/2197/6124/6160/6210/6154/6129/6224/6230/6191/6136/6206/6208/6168/6232/6134/6146/4736/6189/6125/6164/6228/6133/6122/6138/6207/6203/6196
136 WP3875 ATR Signaling 8 0.781003687085597 1.5506309557775 0.0315533980582524 0.129485796476088 0.0976740665039081 2500 tags=75%, list=20%, signal=60% 1111/11073/5883/3364/545/5810
137 WP15 Selenium Micronutrient Network 50 -0.555900230371387 -1.45738739720432 0.0321678321678322 0.131036610448375 0.0988438805776267 1854 tags=26%, list=15%, signal=22% 3043/6648/4790/3039/3949/5743/4524/6347/12/6649/5742/2878/3569
138 WP2374 Oncostatin M Signaling Pathway 64 -0.52821348511576 -1.43895010938035 0.0345285524568393 0.139626409205029 0.105323360164158 2153 tags=30%, list=18%, signal=25% 9180/3716/5578/4792/4790/1432/3949/3717/7078/6777/3726/3977/6347/9021/3572/1958/2353/3727/5579
139 WP23 B Cell Receptor Signaling Pathway 92 -0.492094428626572 -1.41127496856742 0.0347826086956522 0.139634530560807 0.105329486286605 2628 tags=32%, list=21%, signal=25% 2889/7409/8915/5970/7462/5788/5170/4773/4792/8462/4790/1432/9846/23396/3662/3725/2549/2308/695/5336/4609/2534/974/975/8395/933/4208/4209/5579
140 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 45 -0.551646144759052 -1.43634135631229 0.0361613351877608 0.144125033769924 0.108716774475888 3262 tags=51%, list=27%, signal=38% 6774/3055/5601/5595/6194/7006/4791/5970/6778/3716/4792/6776/4790/1432/9846/2242/3717/695/4609/2534/6777/85480/3569
141 WP206 Fatty Acid Omega Oxidation 5 -0.866595883894327 -1.46245802461355 0.0364963503649635 0.144421272158498 0.108940233796169 1529 tags=80%, list=12%, signal=70% 216/126/217/125
142 WP2636 Common Pathways Underlying Drug Addiction 24 -0.629302655429802 -1.47786093871257 0.0376506024096386 0.147932154148509 0.111588571531366 2310 tags=38%, list=19%, signal=30% 801/5578/5500/60/2770/5908/5906/5579/72
143 WP4211 Transcriptional cascade regulating adipogenesis 13 -0.731843560040142 -1.48656016046487 0.0382695507487521 0.149305148695836 0.11262425238884 1050 tags=31%, list=9%, signal=28% 28999/1052/1959/10365
144 WP286 IL-3 Signaling Pathway 44 -0.554662346420084 -1.44260253570813 0.0390516039051604 0.151290829115097 0.1141220960644 3262 tags=45%, list=27%, signal=33% 6774/3055/5293/5595/1439/7040/3635/2889/7409/3716/6776/9846/3725/3717/969/2534/6777/3563/596/2353
145 WP4541 Hippo-Merlin Signaling Dysregulation 95 -0.481263972980716 -1.37790961849811 0.0401002506265664 0.154274575327207 0.116372803353413 2080 tags=36%, list=17%, signal=30% 3684/5159/3683/1004/2324/5573/3688/960/3791/5500/3672/154796/1436/4659/7005/1012/7003/7010/4609/5156/3690/4915/3678/3680/3815/2260/26524/5332/1003/3679/5577/94274/4804/8516
146 WP34 Ovarian Infertility Genes 17 -0.674814596859437 -1.44659434192003 0.0418679549114332 0.159964462213338 0.120664813791934 834 tags=29%, list=7%, signal=27% 2701/6609/894/1958/5241
147 WP4217 Ebola Virus Pathway on Host 118 -0.458831175424282 -1.34852633592062 0.0428921568627451 0.162755170561375 0.122769908251693 2744 tags=28%, list=22%, signal=22% 3123/3127/3113/858/387/4791/1212/3115/3111/55823/5970/3108/3688/3672/60/153090/4790/4240/3384/7099/87/30835/3690/3678/558/9021/2316/388/857/2621/10462/2934/2318
148 WP1601 Fluoropyrimidine Activity 28 0.540549228053908 1.47532902230794 0.0432276657060519 0.162912427218726 0.122888530507 1259 tags=36%, list=10%, signal=32% 23583/7083/7517/6241/8836/7298/5471/7371/6996/1890
149 WP4030 SCFA and skeletal muscle substrate metabolism 2 -0.954183281997241 -1.37242059985368 0.0437375745526839 0.163690853066565 0.123475714739552 115 tags=100%, list=1%, signal=99% 6517
150 WP1424 Globo Sphingolipid Metabolism 20 -0.635512972937628 -1.41849909401341 0.0440251572327044 0.163690853066565 0.123475714739552 2880 tags=45%, list=23%, signal=34% 6483/81849/26301/6482/53947/27090/256435/6489/30815
151 WP4396 Nonalcoholic fatty liver disease 135 -0.448303650812215 -1.33218564897561 0.0445783132530121 0.163734880411581 0.123508925562223 1894 tags=19%, list=15%, signal=16% 7386/4714/8660/4790/6392/7412/355/7385/22877/1350/4724/3725/5465/5563/4092/10000/3570/7381/51422/3953/6347/9021/84701/1346/3569
152 WP4210 Tryptophan catabolism leading to NAD+ production 11 -0.746472837499919 -1.47437584703945 0.0446280991735537 0.163734880411581 0.123508925562223 17 tags=18%, list=0%, signal=18% 349565/23498
153 WP530 Cytokines and Inflammatory Response 14 -0.714034062158728 -1.4716310345101 0.0458265139116203 0.167025583598932 0.125991177443998 2929 tags=64%, list=24%, signal=49% 7040/3123/920/3600/1435/3574/2920/1440/3569
154 WP716 Vitamin A and Carotenoid Metabolism 22 -0.629472273219803 -1.44044342995728 0.048062015503876 0.173368799874824 0.130776009025851 1885 tags=45%, list=15%, signal=39% 5915/4023/6257/948/8854/216/116362/5947/5914/83875
155 WP4239 Epithelial to mesenchymal transition in colorectal cancer 128 -0.447616590432949 -1.32861770557018 0.0481927710843374 0.173368799874824 0.130776009025851 1093 tags=15%, list=9%, signal=14% 7043/1288/10000/5310/7483/8322/3678/5010/3398/26524/6935/1286/7482/8324/9839/117581/4209/7048/7122
156 WP2064 Neural Crest Differentiation 64 -0.507296714214776 -1.38196900112776 0.049136786188579 0.175624384183695 0.132477447313181 2616 tags=41%, list=21%, signal=32% 1488/4791/6615/1004/8313/3688/28514/9734/4855/652/83439/23493/4790/3516/4609/6925/4286/9759/2260/4487/4359/10014/388/5376/2247/6663
157 WP4595 Urea cycle and associated pathways 16 0.640253061310679 1.49763620923435 0.0494791666666667 0.175714476495726 0.132545405982906 864 tags=25%, list=7%, signal=23% 5831/10165/162417/10166
158 WP4008 NO/cGMP/PKG mediated Neuroprotection 25 -0.609319937888644 -1.43717569726893 0.0498489425981873 0.175900090442011 0.132685418782973 2621 tags=48%, list=21%, signal=38% 1742/5970/801/842/4792/4790/5139/4846/817/596/4881/5138
159 WP4585 Cancer immunotherapy by PD-1 blockade 21 -0.620866606987424 -1.3985791186433 0.0519685039370079 0.182218678361407 0.137451672638189 4417 tags=81%, list=36%, signal=52% 5781/80380/925/10725/3932/926/7535/5133/6774/915/3123/916/4773/4790/3725/4772/4776
160 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 27 -0.602719596112229 -1.43816699772577 0.0551301684532925 0.190946691176471 0.144035410216718 2399 tags=41%, list=20%, signal=33% 5970/9734/4773/4792/4790/4772/4776/9759/5532/10014/5533
161 WP2877 Vitamin D Receptor Pathway 118 -0.451549634647416 -1.32712554619747 0.0551470588235294 0.190946691176471 0.144035410216718 1468 tags=23%, list=12%, signal=20% 7077/3662/1026/3394/3488/50486/2308/4609/5734/7078/6546/78989/6304/9365/154/3726/4345/5243/3400/11096/7168/7869/79689/623/9314/6422/6517
162 WP3995 Prion disease pathway 31 -0.584578945178294 -1.42908444719709 0.0575757575757576 0.197162702795572 0.148724288447354 1683 tags=32%, list=14%, signal=28% 4790/5452/3662/5621/2534/2260/596/4208/1879/4684
163 WP2943 Hypoxia-mediated EMT and Stemness 2 -0.941315874717716 -1.35391315463816 0.0576540755467197 0.197162702795572 0.148724288447354 539 tags=100%, list=4%, signal=96% 6935
164 WP2485 NAD Biosynthesis II (from tryptophan) 6 -0.837613690804246 -1.44635517894852 0.0581818181818182 0.197746793084216 0.149164880969854 17 tags=33%, list=0%, signal=33% 64802/23498
165 WP4462 Platelet-mediated interactions with vascular and circulating cells 15 -0.686870057317304 -1.43559163068704 0.0607553366174056 0.205234490768553 0.154813020777343 2929 tags=60%, list=24%, signal=46% 7040/7042/6404/7412/7099/7043/6401/6347/6403
166 WP4747 Netrin-UNC5B signaling Pathway 44 -0.539244900584092 -1.40250382231845 0.0627615062761506 0.210726511981742 0.158955776661128 2884 tags=39%, list=24%, signal=30% 3635/23365/387/2185/3791/5578/1432/7412/3725/56963/54538/2534/9423/10413/6401/1003/6347
167 WP3297 EV release from cardiac cells and their functional effects 4 -0.862950715278098 -1.39793242352714 0.0639853747714808 0.213541551948195 0.161079225011274 265 tags=50%, list=2%, signal=49% 6387/10365
168 WP4538 Regulatory circuits of the STAT3 signaling pathway 67 -0.493240817393167 -1.35894337979665 0.064388961892247 0.213601705917993 0.161124600511958 2221 tags=31%, list=18%, signal=26% 5788/9180/3716/57521/1432/3587/1844/5602/3717/5156/3570/5789/3563/3590/80854/3977/9021/2690/3572/5579/185
169 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 58 -0.513713748037688 -1.37854779911699 0.0652173913043478 0.215062111801242 0.162226217718209 1465 tags=26%, list=12%, signal=23% 1026/7099/7402/7414/7094/22943/2534/3611/55742/3690/3913/1028/7431/1286/11346
170 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 16 -0.665216071927142 -1.41047674691195 0.0663430420711974 0.216841869827779 0.163568729472978 1244 tags=31%, list=10%, signal=28% 5906/9252/2908/6722/1958
171 WP1438 Influenza A virus infection 1 -0.961591780151676 -1.28882821931731 0.0665399239543726 0.216841869827779 0.163568729472978 473 tags=100%, list=4%, signal=96%
172 WP2267 Synaptic Vesicle Pathway 31 -0.568798832477696 -1.39050776936521 0.0681818181818182 0.219993483484707 0.165946062974403 1703 tags=29%, list=14%, signal=25% 2055/10497/6812/2054/6571/291/6844/6581/477
173 WP322 Osteoblast Signaling 7 -0.808850305525022 -1.43995220701171 0.0683012259194396 0.219993483484707 0.165946062974403 989 tags=57%, list=8%, signal=53% 5159/5156/3690/5745
174 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 69 -0.48541180834441 -1.34220701754833 0.0700132100396301 0.224204152381243 0.169122265809146 1778 tags=26%, list=14%, signal=22% 83439/81029/6423/3725/85407/5176/8061/22943/4609/4920/83595/4919/7482/8324/894/9314/6422/64321
175 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 40 -0.538270309433591 -1.37511668032948 0.0725462304409673 0.230980526806298 0.174233838385142 1891 tags=35%, list=15%, signal=30% 4791/5970/7188/4792/8737/4790/1432/3725/7185/330/8742/6347/9020/3569
176 WP712 Estrogen signaling pathway 21 -0.61006551356368 -1.37424831464941 0.0740157480314961 0.234312710911136 0.176747380261678 1683 tags=29%, list=14%, signal=25% 4790/1432/3725/2099/596/2353
177 WP3935 Leptin Insulin Overlap 14 -0.687575875133128 -1.41710045787903 0.0752864157119476 0.236981104002381 0.178760209555282 2110 tags=64%, list=17%, signal=53% 3643/6774/8503/5170/8660/3717/8835/3953/9021
178 WP197 Cholesterol Biosynthesis Pathway 14 0.62819710570988 1.42438853835171 0.0767263427109974 0.2401491178638 0.181149914102087 1003 tags=29%, list=8%, signal=26% 1717/4598/6713/2224
179 WP405 Eukaryotic Transcription Initiation 41 0.45874240039583 1.35204407271458 0.0784982935153584 0.244314913525329 0.184292268040197 2669 tags=37%, list=22%, signal=29% 5437/5436/2960/84172/2968/25885/5439/2071/2967/6883/55703/6877/4331/51728/5438
180 WP2879 Farnesoid X Receptor Pathway 7 -0.789437096627051 -1.40539192706019 0.0805604203152364 0.249332250584586 0.188076958924721 1784 tags=57%, list=15%, signal=49% 8660/5244/10891/2289
181 WP2637 Structural Pathway of Interleukin 1 (IL-1) 49 -0.509258373676372 -1.32314141379428 0.082036775106082 0.252490963382053 0.190459647468506 3254 tags=43%, list=27%, signal=32% 1977/7189/5601/5606/5595/4155/23118/10010/5970/9261/54472/4792/4790/1432/5602/9252/4609/4215/1326/9020/2353
182 WP4792 Purine metabolism 11 0.672064316569719 1.4295743423481 0.0831234256926952 0.254421976982062 0.191916254725211 704 tags=27%, list=6%, signal=26% 3704/1716/3251
183 WP4571 Urea cycle and related diseases 6 0.766274061423484 1.43392081300156 0.084070796460177 0.255907809005154 0.193037051444131 864 tags=50%, list=7%, signal=47% 10165/162417/10166
184 WP2034 Leptin signaling pathway 75 -0.471684908853682 -1.313839222857 0.0868421052631579 0.261432861432861 0.197204723520513 2636 tags=31%, list=21%, signal=24% 387/8648/9475/5970/6093/5728/3716/4790/1432/3717/4846/5563/2308/5336/2534/8835/5140/6777/2099/3953/9021/32/1073
185 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 123 -0.431712318811825 -1.2774937379221 0.0872727272727273 0.261432861432861 0.197204723520513 1891 tags=24%, list=15%, signal=21% 4792/1938/6776/8536/8660/23373/4790/1432/25759/4137/3725/5602/4205/3717/5906/9252/5563/2534/4915/6777/1808/4776/1959/627/32/4804/4208/1958/2353/4684
186 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism 66 -0.481297078415223 -1.32003744064085 0.0873015873015873 0.261432861432861 0.197204723520513 1720 tags=21%, list=14%, signal=18% 23236/1432/9658/2308/63976/10000/3690/9728/7067/2260/6567/10891/4881/11343
187 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms 44 -0.518173230910201 -1.34769922939926 0.0878661087866109 0.261708732622486 0.197412819401723 1738 tags=20%, list=14%, signal=18% 60/7005/5602/7003/3690/58/59/70/72
188 WP1995 Effects of Nitric Oxide 4 -0.848071387134949 -1.37382873500432 0.0895795246800731 0.264516669458871 0.199530909700117 1574 tags=75%, list=13%, signal=65% 3039/4846/316
189 WP2865 IL1 and megakaryocytes in obesity 21 -0.604117202509258 -1.3608490054608 0.0897637795275591 0.264516669458871 0.199530909700117 1683 tags=33%, list=14%, signal=29% 4790/7077/114548/1839/2205/6347/8991
190 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk 6 -0.796916002083479 -1.37608016613682 0.0909090909090909 0.265071770334928 0.199949634852682 2054 tags=50%, list=17%, signal=42% 3791/54538/9353
191 WP4666 Hepatitis B infection 130 -0.422343241745898 -1.25151206742508 0.0909090909090909 0.265071770334928 0.199949634852682 2231 tags=25%, list=18%, signal=20% 842/3339/6778/3716/5578/4773/6776/4790/1432/7098/355/1654/1026/7099/3725/5602/3717/4772/7043/4609/10000/6777/4776/90993/1959/9586/596/2353/7048/5579/1960/3569
192 WP673 ErbB Signaling Pathway 81 -0.4605128471235 -1.29950270167019 0.0920881971465629 0.266130663430421 0.200748381877023 2110 tags=25%, list=17%, signal=21% 5170/685/5578/6776/25759/1026/3725/5602/2549/374/817/2308/5336/4609/25/10000/6777/1839/5579/9542
193 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 16 -0.645040073787789 -1.36769699846292 0.0922330097087379 0.266130663430421 0.200748381877023 1267 tags=44%, list=10%, signal=39% 19/10062/5915/5465/5244/5243/5914
194 WP704 Methylation Pathways 7 -0.776780569729948 -1.38286020059103 0.0928196147110333 0.266435577978821 0.200978385820999 1572 tags=57%, list=13%, signal=50% 3176/4837/4144/11185
195 WP4331 Neovascularisation processes 37 -0.527009536551983 -1.34194147805312 0.0938833570412518 0.268099895880688 0.202233818477357 2594 tags=49%, list=21%, signal=38% 5601/5595/7040/7042/4791/2324/5970/4855/3791/4254/7852/4790/284/7043/3815/4093/94/6387
196 WP3634 Insulin signalling in human adipocytes (normal condition) 8 -0.751366752993145 -1.39552769939113 0.0949152542372881 0.268280871670702 0.202370332611189 115 tags=38%, list=1%, signal=37% 3643/6194/6517
197 WP3635 Insulin signalling in human adipocytes (diabetic condition) 8 -0.751366752993145 -1.39552769939113 0.0949152542372881 0.268280871670702 0.202370332611189 115 tags=38%, list=1%, signal=37% 3643/6194/6517
198 WP357 Fatty Acid Biosynthesis 20 0.5581414734364 1.39298884114133 0.0956284153005464 0.268924579068542 0.202855895668271 281 tags=15%, list=2%, signal=15% 47/2194/6319
199 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment 24 -0.579912872491187 -1.36187345582706 0.0963855421686747 0.269684799805282 0.203429347373545 3325 tags=54%, list=27%, signal=40% 5133/6774/7189/7040/7042/4791/6778/3566/4790/7099/7043/6347/7048
200 WP129 Matrix Metalloproteinases 22 0.535946775951655 1.3746444569853 0.0980392156862745 0.272093397745572 0.205246207305704 1504 tags=32%, list=12%, signal=28% 4320/4322/4312/4321/6942/4318/4323
201 WP3967 miR-509-3p alteration of YAP1/ECM axis 17 -0.629257824320371 -1.34893467406777 0.0982286634460548 0.272093397745572 0.205246207305704 1577 tags=35%, list=13%, signal=31% 7005/5090/10082/7003/10413/1909
202 WP272 Blood Clotting Cascade 12 -0.685631500825806 -1.37300289697842 0.0995024875621891 0.274250637360461 0.206873461964855 1548 tags=33%, list=13%, signal=29% 2152/7450/2157/2159
203 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment 8 -0.747715740054682 -1.38874660391923 0.1 0.274257425742574 0.206878582595102 2399 tags=50%, list=20%, signal=40% 5970/4792/4790/3569
204 WP2874 Liver X Receptor Pathway 5 0.781145675082165 1.38858579160511 0.10352422907489 0.281933842239186 0.212669077273336 1631 tags=60%, list=13%, signal=52% 2194/6319/6720
205 WP28 Selenium Metabolism and Selenoproteins 28 -0.554760669368141 -1.33044103553782 0.10381679389313 0.281933842239186 0.212669077273336 1683 tags=25%, list=14%, signal=22% 4790/4780/3725/8991/1390/2353/2878
206 WP313 Signaling of Hepatocyte Growth Factor Receptor 34 -0.523915545722487 -1.3036221311401 0.10762331838565 0.290845455539757 0.219391308852904 2628 tags=35%, list=21%, signal=28% 2889/2185/3688/1793/5728/3672/3725/5908/2549/5906/3082/2353
207 WP3972 PDGFR-beta pathway 29 -0.545184974055366 -1.31332318559275 0.108728943338438 0.292250143871091 0.220450897048876 2137 tags=34%, list=17%, signal=29% 6778/3716/5578/6776/3725/3717/6777/6722/2353/5579
208 WP3940 One carbon metabolism and related pathways 39 -0.512257616041992 -1.30816227173947 0.109530583214794 0.292250143871091 0.220450897048876 760 tags=13%, list=6%, signal=12% 4524/1036/6649/2878/23743
209 WP53 ID signaling pathway 13 0.611338225699918 1.37488358594489 0.109725685785536 0.292250143871091 0.220450897048876 1631 tags=38%, list=13%, signal=33% 898/5933/1017/2002/6720
210 WP51 Regulation of Actin Cytoskeleton 117 -0.422153446476017 -1.23738330690987 0.110565110565111 0.293076895947709 0.221074534849403 3203 tags=39%, list=26%, signal=29% 5293/9564/5595/8503/50649/324/22800/6655/5286/8826/23533/5159/4478/387/7409/9475/10152/6093/1793/22808/1131/3672/2909/7454/10163/60/4659/23396/87/55970/7414/26999/5305/5156/9459/6237/2260/8395/1073/2258/623/2252/624/2934/2247/4638
211 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) 20 -0.59950695514597 -1.33813172813509 0.111635220125786 0.293148667924355 0.221128674075563 1433 tags=25%, list=12%, signal=22% 8989/3248/5465/4056/8309
212 WP3927 BMP Signaling Pathway in Eyelid Development 16 -0.6306524227717 -1.33719044870069 0.111650485436893 0.293148667924355 0.221128674075563 3193 tags=50%, list=26%, signal=37% 5601/5595/4089/652/3725/5308/3625/6422
213 WP3933 Kennedy pathway from Sphingolipids 12 0.626064103213399 1.37455736891755 0.115288220551378 0.299956542492181 0.22626400792209 2533 tags=50%, list=21%, signal=40% 9791/5833/10400/8879/10390/55500
214 WP4136 Fibrin Complement Receptor 3 Signaling Pathway 30 -0.535809368717357 -1.30207540671318 0.115326251896813 0.299956542492181 0.22626400792209 3977 tags=57%, list=32%, signal=38% 5327/7305/868/114609/3551/929/7189/148022/83593/3684/387/23643/4790/7098/7099/6347/3569
215 WP3672 LncRNA-mediated mechanisms of therapeutic resistance 7 -0.75770569431584 -1.34890223733949 0.117338003502627 0.303762868880632 0.229135206052843 1465 tags=43%, list=12%, signal=38% 1026/5243/55384
216 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 18 0.556284465267421 1.33590851559974 0.119363395225464 0.307568934673987 0.232006207610817 2083 tags=22%, list=17%, signal=18% 55872/1978/5604/2475
217 WP2333 Trans-sulfuration pathway 10 0.647308682006739 1.35533459222229 0.122249388753056 0.313302917058334 0.236331480281509 1670 tags=30%, list=14%, signal=26% 1786/191/2730
218 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 12 -0.666981491805223 -1.33565555167254 0.122719734660033 0.313302917058334 0.236331480281509 1891 tags=50%, list=15%, signal=42% 3551/7189/4792/4790/6237/9020
219 WP4321 Thermogenesis 90 -0.437856245934515 -1.24858410410469 0.124685138539043 0.313370031593615 0.236382106294253 1846 tags=22%, list=15%, signal=19% 2182/6604/60/1432/9658/108/5563/63976/90993/9586/51422/5592/2260/115/6196/196883/10891/4881/111/11343
220 WP3981 miRNA regulation of prostate cancer signaling pathways 32 -0.523354952521039 -1.28583941456712 0.125188536953243 0.313370031593615 0.236382106294253 2338 tags=34%, list=19%, signal=28% 5159/23228/842/367/4792/4790/1026/2308/10000/90993/596
221 WP4400 FABP4 in ovarian cancer 1 -0.928565603848977 -1.24456300316878 0.125475285171103 0.313370031593615 0.236382106294253 878 tags=100%, list=7%, signal=93%
222 WP4535 Envelope proteins and their potential roles in EDMD physiopathology 41 -0.498323455240057 -1.28356503808783 0.125528913963329 0.313370031593615 0.236382106294253 1723 tags=22%, list=14%, signal=19% 2010/3799/108/7043/115/196883/23345/6722/111
223 WP2870 Extracellular vesicle-mediated signaling in recipient cells 27 -0.547646696992832 -1.30675592947198 0.125574272588055 0.313370031593615 0.236382106294253 3164 tags=41%, list=26%, signal=30% 7103/324/7040/23533/4089/7042/4240/7043/3082/7049/7048
224 WP4155 Endometrial cancer 59 -0.474433113541208 -1.269837304034 0.129427792915531 0.321538104373114 0.242543468432693 2414 tags=37%, list=20%, signal=30% 5293/2309/5595/8503/324/6655/8313/842/5728/5170/1647/51426/83439/10912/1026/4609/3611/10000/4616/2260/2247/2353
225 WP4545 Oxysterols derived from cholesterol 10 -0.689027938108387 -1.33384495316058 0.133220910623946 0.329221999878722 0.248339604696661 903 tags=80%, list=7%, signal=74% 53342/9420/7376/1593/2099/9023/2053/1880
226 WP195 IL-1 signaling pathway 55 -0.47719026359511 -1.2699676196789 0.133977900552486 0.329221999878722 0.248339604696661 2399 tags=24%, list=20%, signal=19% 5970/9261/54472/4792/4790/1432/3725/4215/57161/11213/6347/9020/3316
227 WP2436 Dopamine metabolism 9 -0.702346905291786 -1.33818347766561 0.136134453781513 0.329221999878722 0.248339604696661 726 tags=67%, list=6%, signal=63% 4128/5566/5515/5567/5516/4129
228 WP117 GPCRs, Other 22 -0.573012284766239 -1.31124406267236 0.136434108527132 0.329221999878722 0.248339604696661 2136 tags=41%, list=17%, signal=34% 1131/27239/3579/59352/154/1909/1880/1901/5737
229 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) 41 0.436915078207973 1.28771275831709 0.136518771331058 0.329221999878722 0.248339604696661 2459 tags=37%, list=20%, signal=29% 2194/6319/1717/10682/4598/6713/1718/2224/3992/6720/51478/7108/6646/4597/9415
230 WP4507 Molybdenum cofactor (Moco) biosynthesis 7 -0.746174812851297 -1.32837443621208 0.136602451838879 0.329221999878722 0.248339604696661 62 tags=43%, list=1%, signal=43% 54996/4338/316
231 WP560 TGF-beta Receptor Signaling 46 -0.485805165126977 -1.26333149329637 0.136680613668061 0.329221999878722 0.248339604696661 2795 tags=48%, list=23%, signal=37% 4091/25805/4089/7030/10468/864/4052/2022/3716/652/6497/7057/4790/3725/3976/23090/4092/4093/9839/7049/2353/7048
232 WP500 Glycogen Synthesis and Degradation 36 -0.500746250862426 -1.26823953268594 0.137733142037303 0.330321041942276 0.249168636996169 2727 tags=42%, list=22%, signal=32% 805/3098/5236/5527/808/801/2632/7360/5834/5257/2992/5521/5516/5525/5837
233 WP4329 miRNAs involvement in the immune response in sepsis 32 -0.515204687738098 -1.2658148945992 0.14027149321267 0.333291843000581 0.251409579462722 2828 tags=31%, list=23%, signal=24% 23118/4791/6351/5970/4792/4790/1432/7412/7099/3569
234 WP3945 TYROBP Causal Network 57 -0.470607876805127 -1.25984734373655 0.140518417462483 0.333291843000581 0.251409579462722 2514 tags=39%, list=20%, signal=31% 3684/864/4066/920/678/10019/10257/3142/113277/4094/64092/5341/6776/6039/3587/1806/951/54518/7133/5996/3071/718
235 WP4494 Selective expression of chemokine receptors during T-cell polarization 16 -0.61627781430795 -1.30671155343687 0.140776699029126 0.333291843000581 0.251409579462722 2929 tags=50%, list=24%, signal=38% 7040/7042/6351/920/3566/940/7852/7043
236 WP3963 Mevalonate pathway 7 0.69055105403028 1.33106894039181 0.1415313225058 0.333652564545589 0.251681679887135 1003 tags=43%, list=8%, signal=39% 4598/39/2224
237 WP4583 Biomarkers for urea cycle disorders 8 -0.720401424353174 -1.33801520810018 0.144067796610169 0.33819304797472 0.25510666928741 992 tags=25%, list=8%, signal=23% 2593/2159
238 WP2290 RalA downstream regulated genes 11 0.616984343503787 1.31241157335274 0.148614609571788 0.343953394521994 0.259451829042811 917 tags=18%, list=7%, signal=17% 5881/4893
239 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma 11 0.618066957558873 1.31471444413112 0.148614609571788 0.343953394521994 0.259451829042811 1153 tags=27%, list=9%, signal=25% 84759/2146/23512
240 WP3407 FTO Obesity Variant Mechanism 7 -0.737141817031022 -1.31229348504166 0.148861646234676 0.343953394521994 0.259451829042811 1086 tags=57%, list=9%, signal=52% 79068/84159/63976/10891
241 WP176 Folate Metabolism 44 -0.480683832405608 -1.25019432088337 0.149232914923291 0.343953394521994 0.259451829042811 1854 tags=30%, list=15%, signal=25% 3043/6648/4790/1435/3039/3949/4524/6347/2350/12/6649/2878/3569
242 WP4705 Pathways of nucleic acid metabolism and innate immune sensing 13 0.583090004904789 1.31135408055709 0.149625935162095 0.343953394521994 0.259451829042811 2232 tags=31%, list=18%, signal=25% 10535/103/3661/4938
243 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 15 -0.617996348281414 -1.29164224868534 0.151067323481117 0.345831806646854 0.260868757816456 236 tags=20%, list=2%, signal=20% 9261/6722/3708
244 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 21 -0.570189895481792 -1.28442353398851 0.152755905511811 0.348258319561907 0.262699131419489 2384 tags=38%, list=19%, signal=31% 2052/10257/9429/1432/4780/3725/1066/2353
245 WP4565 Neural Crest Cell Migration in Cancer 36 -0.487978917708635 -1.23590372067592 0.156384505021521 0.355069736811158 0.267837137590784 1374 tags=17%, list=11%, signal=15% 3725/10000/4915/627/4804/2353
246 WP4399 MicroRNA network associated with chronic lymphocytic leukemia 4 -0.806567575085458 -1.30659485532063 0.157221206581353 0.355512442637018 0.268171080613521 1350 tags=75%, list=11%, signal=67% 7535/4170/596
247 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 13 -0.639079564832203 -1.29813292391979 0.15973377703827 0.359725660484558 0.271349206179688 1374 tags=31%, list=11%, signal=27% 3725/3690/8076/6263
248 WP4478 LTF danger signal response pathway 14 -0.630241241967544 -1.29893323030499 0.160392798690671 0.359747410828469 0.271365612956303 1683 tags=21%, list=14%, signal=19% 4790/7099/3569
249 WP4657 22q11.2 Deletion Syndrome 58 -0.459139688763816 -1.2320986344056 0.161684782608696 0.360412238325282 0.271867107381982 1672 tags=21%, list=14%, signal=18% 8854/8036/4942/5308/7450/2260/9464/59/6722/70/6517/7122
250 WP3617 Photodynamic therapy-induced NF-kB survival signaling 30 -0.514681128728561 -1.25073147119671 0.16236722306525 0.360412238325282 0.271867107381982 1683 tags=30%, list=14%, signal=26% 4790/7412/8837/5743/599/6401/330/2920/3569
251 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 17 -0.597488701604883 -1.28083147448989 0.162640901771337 0.360412238325282 0.271867107381982 1638 tags=35%, list=13%, signal=31% 4780/308/3490/5310/23411/2252
252 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 16 0.549418779946081 1.28516286543976 0.1640625 0.361713241055106 0.272848483182362 1153 tags=25%, list=9%, signal=23% 2146/5928/22823/23512
253 WP4720 Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway 4 -0.804835250156437 -1.30378858476139 0.164533820840951 0.361713241055106 0.272848483182362 1267 tags=75%, list=10%, signal=67% 66002/5465/2053
254 WP4225 Pyrimidine metabolism and related diseases 12 0.580709706759817 1.27497935519964 0.165413533834586 0.362209872507355 0.273223103525404 1862 tags=42%, list=15%, signal=35% 6241/790/7298/1890/7372
255 WP2542 Sulindac Metabolic Pathway 4 -0.802265749614226 -1.29962613601822 0.16819012797075 0.366790254237288 0.27667818911686 1610 tags=100%, list=13%, signal=87% 22921/4482/253827
256 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) 25 -0.539379175210211 -1.27220954710782 0.169184290030211 0.366790254237288 0.27667818911686 1261 tags=24%, list=10%, signal=22% 3717/4609/2908/2099/857/5241
257 WP1455 Serotonin Transporter Activity 8 -0.706628333403954 -1.31243418545138 0.169491525423729 0.366790254237288 0.27667818911686 949 tags=38%, list=8%, signal=35% 3690/5516/7041
258 WP3851 TLR4 Signaling and Tolerance 25 -0.536910168476245 -1.26638601130371 0.170694864048338 0.367957022111982 0.277558308528324 1891 tags=36%, list=15%, signal=31% 148022/3635/23118/4792/8737/4790/7099/11213/3569
259 WP1603 Nicotine Activity on Chromaffin Cells 1 -0.908423713610046 -1.21756668615967 0.173003802281369 0.370772619451034 0.279682177317234 1125 tags=100%, list=9%, signal=91%
260 WP1545 miRNAs involved in DNA damage response 14 0.568979686181884 1.29011760192145 0.173913043478261 0.370772619451034 0.279682177317234 287 tags=21%, list=2%, signal=21% 898/993/1869
261 WP2805 exRNA mechanism of action and biogenesis 5 0.728782551156112 1.29550367874552 0.174008810572687 0.370772619451034 0.279682177317234 2558 tags=40%, list=21%, signal=32% 57510/29102
262 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions 31 -0.503616815115451 -1.23116127216815 0.175757575757576 0.373063973063973 0.281410597200071 2932 tags=45%, list=24%, signal=34% 2309/83706/83593/4023/387/3683/4303/1432/7005/5906/2308/7003/10413/26524
263 WP1423 Ganglio Sphingolipid Metabolism 8 -0.703892259759247 -1.3073524240565 0.177966101694915 0.376310001293828 0.283859149750427 343 tags=75%, list=3%, signal=73% 8869/6483/8705/6482/6489/30815
264 WP4342 Vitamins A and D - action mechanisms 3 -0.829052162666763 -1.27659659137119 0.178846153846154 0.376732962854636 0.284178199227229 606 tags=67%, list=5%, signal=63% 6256/5914
265 WP364 IL-6 signaling pathway 41 -0.470650088907796 -1.21228489837782 0.180535966149506 0.378851989571313 0.285776629032512 1324 tags=17%, list=11%, signal=15% 2549/3717/3570/3726/9021/3572/3569
266 WP3996 Ethanol effects on histone modifications 28 -0.512185591196412 -1.22833640877072 0.184732824427481 0.386196168803111 0.291316509623475 962 tags=32%, list=8%, signal=30% 8854/216/8850/126/4524/9759/10014/217/125
267 WP58 Monoamine GPCRs 5 -0.76765070158419 -1.29547918412329 0.186131386861314 0.387657098951759 0.292418522294981 2136 tags=100%, list=17%, signal=83% 1131/152/154/150
268 WP2645 Heroin metabolism 2 -0.86609036046322 -1.24571481649357 0.196819085487078 0.406563924880596 0.306680368948502 1645 tags=100%, list=13%, signal=87% 1066
269 WP2826 Cocaine metabolism 2 -0.86609036046322 -1.24571481649357 0.196819085487078 0.406563924880596 0.306680368948502 1645 tags=100%, list=13%, signal=87% 1066
270 WP100 Glutathione metabolism 16 -0.586666158496733 -1.24392510896885 0.197411003236246 0.406563924880596 0.306680368948502 70 tags=12%, list=1%, signal=12% 2678/2878
271 WP550 Biogenic Amine Synthesis 3 0.806213880187264 1.24234199325272 0.201244813278008 0.412924542800061 0.311478326983896 621 tags=33%, list=5%, signal=32% 2571
272 WP3584 MECP2 and Associated Rett Syndrome 51 -0.45231991745164 -1.18782464349592 0.205020920502092 0.417579374846173 0.314989572133632 1651 tags=25%, list=13%, signal=22% 50937/6446/26084/4354/4204/2593/1052/3479/627/1465/2289/4208/2247
273 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 46 -0.455768929026883 -1.18522256047879 0.205020920502092 0.417579374846173 0.314989572133632 1674 tags=30%, list=14%, signal=26% 1432/4780/8837/355/1026/3725/4170/5156/3726/1839/596/2252/2353/3569
274 WP4259 Disorders of Folate Metabolism and Transport 11 0.581928542297901 1.23784300496009 0.206549118387909 0.419133045236107 0.316161540867821 961 tags=36%, list=8%, signal=34% 6472/7298/2618/4522
275 WP47 Hedgehog Signaling Pathway Netpath 12 -0.619709676284936 -1.24099196113358 0.207296849087894 0.419133045236107 0.316161540867821 3357 tags=92%, list=27%, signal=67% 25942/406/2737/6608/10284/51684/2736/374654/5727/2735/8643
276 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 52 -0.448218619434276 -1.18190139061762 0.2125 0.428042203506043 0.322881920562225 3220 tags=38%, list=26%, signal=28% 7189/9060/5601/5595/1513/23118/2274/4791/5970/7188/4792/4790/1432/7412/9846/3725/7185/4772/4286/2353
277 WP4629 Computational Model of Aerobic Glycolysis 11 0.570209984314 1.21291600108551 0.214105793450882 0.428042203506043 0.322881920562225 2109 tags=45%, list=17%, signal=38% 2023/7167/5230/2597/2821
278 WP127 IL-5 Signaling Pathway 38 -0.465083592089403 -1.18175225508272 0.214285714285714 0.428042203506043 0.322881920562225 1402 tags=26%, list=11%, signal=23% 3716/6776/4137/3725/3717/695/4609/6777/596/2353
279 WP2526 PDGF Pathway 39 -0.46291059179232 -1.18214381281481 0.214793741109531 0.428042203506043 0.322881920562225 2732 tags=26%, list=22%, signal=20% 5321/5159/387/7409/3716/4792/4790/3725/6722/2353
280 WP4312 Rett syndrome causing genes 37 -0.459999509699044 -1.17131167300681 0.217638691322902 0.430884755701784 0.325026122009516 1768 tags=30%, list=14%, signal=26% 6595/8831/85358/6907/6594/4204/6812/6925/2775/10014/4208
281 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma 13 -0.609637031164943 -1.23832765956726 0.217970049916805 0.430884755701784 0.325026122009516 1683 tags=69%, list=14%, signal=60% 5970/3716/4790/3717/3570/3590/6935/3572/3569
282 WP262 EBV LMP1 signaling 20 -0.549861542676863 -1.22732050065718 0.218553459119497 0.430884755701784 0.325026122009516 2568 tags=40%, list=21%, signal=32% 4791/5970/4792/4790/7185/9260/4215/9020
283 WP4724 Omega-9 FA synthesis 12 0.553768985102902 1.21582955362596 0.220551378446115 0.433096719722318 0.32669465652624 1248 tags=25%, list=10%, signal=22% 2194/6319/3992
284 WP3595 mir-124 predicted interactions with cell cycle and differentiation 6 0.666337498044347 1.24691054419122 0.221238938053097 0.433096719722318 0.32669465652624 768 tags=33%, list=6%, signal=31% 51804/5725
285 WP136 Phase I biotransformations, non P450 5 -0.739821662940272 -1.24851519359614 0.224452554744526 0.437840546931222 0.330273032741203 1645 tags=60%, list=13%, signal=52% 8824/2098/1066
286 WP4760 PKC-gamma calcium signaling pathway in ataxia 12 -0.605157079423319 -1.21184983795882 0.225538971807629 0.438416106601495 0.330707190425221 1720 tags=50%, list=14%, signal=43% 23236/2767/9630/5332/6263/3708
287 WP2113 Type III interferon signaling 6 0.664747957066106 1.2439360524179 0.22787610619469 0.441410359551952 0.332965823184733 2081 tags=67%, list=17%, signal=55% 7297/6773/10379/6772
288 WP3640 Imatinib and Chronic Myeloid Leukemia 20 -0.544154327300876 -1.21458168935841 0.229559748427673 0.443122301842965 0.334257179995548 2687 tags=60%, list=22%, signal=47% 5159/4066/5292/1647/9429/1436/9846/4609/25/5156/3815/5243
289 WP395 IL-4 Signaling Pathway 53 -0.439487791416093 -1.16371689376347 0.230769230769231 0.443910256410256 0.334851551956815 2150 tags=47%, list=18%, signal=39% 6774/5293/3269/1051/5595/3635/9655/5970/9046/6778/3716/4792/3566/6776/8660/4790/1432/9846/2242/4783/3717/6777/9021/2316/2353
290 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 1 -0.875071352850037 -1.17286428269115 0.23384030418251 0.446715615576242 0.336967697860095 1534 tags=100%, list=13%, signal=87%
291 WP3408 Evolocumab Mechanism 1 -0.875071352850037 -1.17286428269115 0.23384030418251 0.446715615576242 0.336967697860095 1534 tags=100%, list=13%, signal=87%
292 WP4484 Control of immune tolerance by vasoactive intestinal peptide 4 -0.761386568477861 -1.23340412386154 0.235831809872029 0.448971899206544 0.338669663661406 2929 tags=75%, list=24%, signal=57% 7040/940/355
293 WP399 Wnt Signaling Pathway and Pluripotency 86 -0.400753272428136 -1.13936583032022 0.236775818639798 0.449225354542631 0.33886085075703 1778 tags=23%, list=14%, signal=20% 960/5578/83439/81029/3949/5587/3725/5602/85407/8061/5048/4609/8322/5521/5516/7482/8324/894/120892/5579
294 WP3944 Serotonin and anxiety-related events 6 -0.718857337788404 -1.24129183279836 0.238181818181818 0.449734321700341 0.339244776201853 435 tags=67%, list=4%, signal=64% 5341/84812/2353/5579
295 WP134 Pentose Phosphate Metabolism 7 0.633352370074243 1.22081584440301 0.238979118329466 0.449734321700341 0.339244776201853 4501 tags=100%, list=37%, signal=63% 22934/5226/6120/7086/2539/6888/25796
296 WP2037 Prolactin Signaling Pathway 73 -0.413043871266113 -1.14586067120391 0.239735099337748 0.449734321700341 0.339244776201853 1891 tags=26%, list=15%, signal=22% 5970/3688/3716/4792/6776/8660/4790/1432/9846/3725/3717/4609/2534/8835/6777/9021/6196/2316/2353
297 WP2007 Iron metabolism in placenta 8 0.616110639410739 1.22324675984462 0.240291262135922 0.449734321700341 0.339244776201853 2934 tags=62%, list=24%, signal=48% 7037/55240/4891/3658/57192
298 WP3585 Cytosine methylation 8 0.612319276791936 1.21571926114198 0.242718446601942 0.450611371237458 0.33990635451505 1135 tags=38%, list=9%, signal=34% 1786/6996/200424
299 WP12 Osteoclast Signaling 12 0.54090801631812 1.18759260580576 0.243107769423559 0.450611371237458 0.33990635451505 1097 tags=17%, list=9%, signal=15% 6696/7965
300 WP78 TCA Cycle (aka Krebs or citric acid cycle) 18 -0.546966546511219 -1.18737906735926 0.2432 0.450611371237458 0.33990635451505 2454 tags=50%, list=20%, signal=40% 3421/3419/8803/8801/1743/8802/4967/50/6392
301 WP437 EGF/EGFR Signaling Pathway 155 -0.368829675291429 -1.1140011992856 0.247072599531616 0.456260733801717 0.344167796540532 1374 tags=22%, list=11%, signal=20% 2887/6093/5900/4303/5728/9046/3716/5170/5578/6776/1432/9846/3725/2549/4205/54206/3717/5906/9252/4846/6812/2308/25/10253/4215/6777/6196/857/4208/2353/4209/3727/5579/2354
302 WP2873 Aryl Hydrocarbon Receptor Pathway 31 -0.472697486596291 -1.15557467797251 0.251515151515152 0.462921574549482 0.349192219449257 3009 tags=39%, list=25%, signal=29% 26509/57491/405/7040/1545/8648/51426/4780/3725/3726/10486/3727
303 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 50 -0.436863724954575 -1.14531286777697 0.254545454545455 0.465493793473836 0.351132502392386 3325 tags=44%, list=27%, signal=32% 5133/27040/5601/5595/915/805/3937/8915/920/801/5788/4773/4792/940/3702/4790/3725/2534/6237/1326/9020/2353
304 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer 76 -0.403556638271017 -1.12629855245576 0.254593175853018 0.465493793473836 0.351132502392386 1778 tags=22%, list=14%, signal=19% 83439/81029/6423/3725/85407/5176/8061/22943/4609/4920/4919/7482/8324/894/467/6422/64321
305 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 9 -0.635976954792988 -1.21172862963851 0.25546218487395 0.465546218487395 0.351172047766475 2156 tags=44%, list=18%, signal=37% 4097/4780/7975/23764
306 WP4564 Neural Crest Cell Migration during Development 33 -0.462906758999675 -1.14280373203889 0.26015037593985 0.472535436953038 0.356444173418879 1374 tags=15%, list=11%, signal=13% 3725/10000/627/4804/2353
307 WP4298 Viral Acute Myocarditis 70 -0.405931686802972 -1.12412875804647 0.262187088274045 0.473966086614308 0.357523344833518 2374 tags=30%, list=19%, signal=24% 3108/920/842/199/3716/1604/7100/7852/60/7098/7099/6443/25/2534/6444/1756/596/3908/857/6442/3569
308 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 5 -0.720037570268548 -1.21512776858618 0.262773722627737 0.473966086614308 0.357523344833518 446 tags=40%, list=4%, signal=39% 2950/2053
309 WP111 Electron Transport Chain (OXPHOS system in mitochondria) 70 -0.404845153425867 -1.121119868976 0.263504611330698 0.473966086614308 0.357523344833518 1894 tags=17%, list=15%, signal=15% 293/4698/7386/4714/6392/7385/1350/4724/9481/291/7381/1346
310 WP4698 Vitamin D-sensitive calcium signaling in depression 22 -0.5134032330874 -1.17483858381374 0.268217054263566 0.480881061689371 0.362739467016303 1638 tags=36%, list=13%, signal=32% 4780/23135/775/6546/1593/493/596/3708
311 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 58 -0.419427205786148 -1.12553042163058 0.275815217391304 0.491333243522385 0.370623784302464 1720 tags=21%, list=14%, signal=18% 23236/4790/1432/7099/3725/817/5336/5332/6347/857/5579/3569
312 WP2359 Parkin-Ubiquitin Proteasomal System pathway 59 0.345330038640725 1.09883296877405 0.276119402985075 0.491333243522385 0.370623784302464 2038 tags=27%, list=17%, signal=23% 898/5709/10381/5717/10213/8573/5708/3309/203068/5714/51182/5718/5706/5704/118424/5710
313 WP4519 Cerebral Organic Acidurias, including diseases 7 -0.671021944493466 -1.19458387210409 0.276707530647986 0.491333243522385 0.370623784302464 1075 tags=29%, list=9%, signal=26% 501/137872
314 WP43 Oxidation by Cytochrome P450 30 -0.471308323853424 -1.14533080848849 0.277693474962064 0.491508578686848 0.370756043584797 2669 tags=30%, list=22%, signal=24% 1545/9420/1577/285440/113612/57404/1727/1593/51302
315 WP3942 PPAR signaling pathway 45 -0.429432073950281 -1.11812808518975 0.280945757997218 0.494543732123663 0.373045528506734 2302 tags=33%, list=19%, signal=27% 6257/376497/5170/51129/23205/5360/948/2182/5465/34/3611/1593/2167/10580/8309
316 WP4241 Type 2 papillary renal cell carcinoma 30 -0.469776493910697 -1.14160829407918 0.282245827010622 0.494543732123663 0.373045528506734 3443 tags=47%, list=28%, signal=34% 112398/1387/54583/1513/405/7040/7030/7042/2034/9915/1026/7043/81578/7942
317 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 29 -0.470189982703728 -1.13266402286346 0.284839203675345 0.494543732123663 0.373045528506734 2266 tags=31%, list=18%, signal=25% 3688/5728/4790/84557/3488/114907/3611/3479/10891
318 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 15 0.498153280104064 1.14693137568047 0.28498727735369 0.494543732123663 0.373045528506734 49 tags=7%, list=0%, signal=7% 47
319 WP496 Steroid Biosynthesis 4 0.72097485115291 1.20799571376043 0.285087719298246 0.494543732123663 0.373045528506734 1869 tags=50%, list=15%, signal=42% 3292/51478
320 WP2456 HIF1A and PPARG regulation of glycolysis 6 0.638358622940121 1.19455396140178 0.285398230088496 0.494543732123663 0.373045528506734 4439 tags=100%, list=36%, signal=64% 7167/2597/5468/3939/6513/3091
321 WP3982 miRNA regulation of p53 pathway in prostate cancer 23 0.438123833386753 1.12980029409198 0.286127167630058 0.494543732123663 0.373045528506734 2274 tags=30%, list=19%, signal=25% 637/11200/317/581/27113/64065/836
322 WP2371 Parkinsons Disease Pathway 31 0.407580501350653 1.13752261141839 0.286549707602339 0.494543732123663 0.373045528506734 117 tags=10%, list=1%, signal=10% 835/898/9134
323 WP2112 IL17 signaling pathway 27 -0.473056074409006 -1.12877304583615 0.287901990811639 0.495334481085863 0.373642008343317 3262 tags=48%, list=27%, signal=35% 6774/7189/1051/5595/53342/54756/5970/3716/4790/84818/3717/1052/9020
324 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 15 -0.558397018660697 -1.16707676808741 0.288998357963875 0.495681394154758 0.373903692721716 891 tags=47%, list=7%, signal=43% 9648/79083/94121/83874/94120/5873/25924
325 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 21 -0.512853220289112 -1.15526555423177 0.292913385826772 0.499673517322372 0.376915041567512 1121 tags=24%, list=9%, signal=22% 22943/4609/862/5914/7704
326 WP4561 Cell migration and invasion through p75NTR 28 -0.469638460619927 -1.12629880663174 0.293129770992366 0.499673517322372 0.376915041567512 1374 tags=18%, list=11%, signal=16% 3725/10000/4915/627/4804
327 WP3853 ERK Pathway in Huntington's Disease 13 -0.570317404688672 -1.15845951091432 0.29450915141431 0.500484876943336 0.377527068490413 1214 tags=23%, list=10%, signal=21% 9252/4915/627
328 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy 7 -0.65748108846836 -1.17047782258542 0.297723292469352 0.504399706507709 0.380480113022156 3262 tags=71%, list=27%, signal=52% 208/6774/7040/50804/4790
329 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 10 -0.599135808621072 -1.15982855032112 0.300168634064081 0.506992144120429 0.382435647379461 3114 tags=80%, list=25%, signal=60% 4086/10140/659/4091/4089/650/657/10766
330 WP3941 Oxidative Damage 37 -0.43402300547821 -1.10516685768368 0.307254623044097 0.517383164639604 0.390273829302532 2532 tags=38%, list=21%, signal=30% 712/728/842/727/1647/4790/1026/5602/7185/7133/716/1028/715/596
331 WP3596 miR-517 relationship with ARCN1 and USP1 5 -0.701676650941553 -1.18414207582201 0.308394160583942 0.517728378677284 0.390534232063237 1465 tags=60%, list=12%, signal=53% 3397/1026/3398
332 WP4146 Macrophage markers 9 -0.604332282740576 -1.15143594951473 0.315966386554622 0.527907995618839 0.398212947483715 4008 tags=78%, list=33%, signal=52% 9308/968/9332/5880/929/972/2152
333 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging 6 -0.671287283821893 -1.15914991621715 0.316363636363636 0.527907995618839 0.398212947483715 2187 tags=50%, list=18%, signal=41% 5728/2308/23411
334 WP4300 Extracellular vesicles in the crosstalk of cardiac cells 17 -0.522347184555542 -1.119751240137 0.334943639291465 0.555607802799309 0.419107538877685 1486 tags=53%, list=12%, signal=47% 5728/3791/2114/7099/3479/10611/975/8470/3569
335 WP2857 Mesodermal Commitment Pathway 116 -0.366763454577847 -1.07371031092087 0.334969325153374 0.555607802799309 0.419107538877685 2852 tags=34%, list=23%, signal=27% 23499/4091/203228/4089/655/6001/58499/1488/6615/79776/8313/55809/23576/5573/1466/28514/652/5087/8646/83439/23373/657/4780/5090/5308/3717/57198/22943/84159/7003/4211/9760/6925/8322/10413/2260/2627/6722/9314/64321
336 WP3613 Photodynamic therapy-induced unfolded protein response 24 0.420857258987172 1.08874893331142 0.337278106508876 0.557767376137066 0.420736553916807 1927 tags=33%, list=16%, signal=28% 10130/7184/811/51726/57761/3309/27113/10018
337 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses 8 -0.608349536372598 -1.12989911456391 0.340677966101695 0.56133748281103 0.423429566171345 3938 tags=88%, list=32%, signal=59% 1385/4548/1051/128/10840/216/4524
338 WP1449 Regulation of toll-like receptor signaling pathway 111 -0.365542960124691 -1.06682625453481 0.341463414634146 0.56133748281103 0.423429566171345 3277 tags=36%, list=27%, signal=27% 929/7189/5293/5601/5606/5595/8503/54461/148022/23533/7096/23118/4091/79004/4791/23098/6351/5970/54472/23643/4792/7100/1540/8737/7128/4790/1432/7098/7099/3725/5602/10771/695/8727/10000/57161/11213/1326/2353/3569
339 WP453 Inflammatory Response Pathway 22 -0.482494814890021 -1.10410976887317 0.342635658914729 0.56159809183065 0.423626149452343 3595 tags=55%, list=29%, signal=39% 3932/7132/3561/958/7535/7059/3915/3566/940/7057/7133/3913
340 WP4524 The alternative pathway of fetal androgen synthesis 4 -0.712111533454146 -1.15358129283475 0.343692870201097 0.561669174310937 0.423679768575797 433 tags=50%, list=4%, signal=48% 1528/8630
341 WP4197 The human immune response to tuberculosis 23 0.417643777463188 1.07698788937389 0.346820809248555 0.56511390683441 0.426278208271444 3876 tags=57%, list=32%, signal=39% 7297/6773/10379/3437/6772/4938/6890/4599/5771/3460/9282/5696/3455
342 WP384 Apoptosis Modulation by HSP70 18 0.450898582228663 1.08282595197324 0.350132625994695 0.568837169504578 0.42908674955979 1263 tags=22%, list=10%, signal=20% 835/637/317/839
343 WP615 Senescence and Autophagy in Cancer 93 -0.370743755112995 -1.06290825775089 0.353673723536737 0.572910066781732 0.432159028144305 1745 tags=17%, list=14%, signal=15% 7057/1432/3490/9547/1026/3725/84557/3488/3570/81631/3479/596/23710/3572/2934/3569
344 WP363 Wnt Signaling Pathway (Netpath) 48 -0.410718904977567 -1.06736380224482 0.356241234221599 0.575386716497859 0.434027221070967 1064 tags=27%, list=9%, signal=25% 1452/387/7249/8313/5578/4773/7010/4609/4920/6925/4919/8395/5579
345 WP2876 Pregnane X Receptor pathway 18 -0.504420778584322 -1.09501884064458 0.36 0.579767441860465 0.437331701346389 2634 tags=33%, list=21%, signal=26% 8648/1577/10257/2308/5243/10891
346 WP4224 Purine metabolism and related disorders 19 0.440061045999739 1.06819526275565 0.363387978142077 0.581840866736157 0.438895732651063 743 tags=32%, list=6%, signal=30% 10606/3704/1716/3251/5471/2618
347 WP4288 MTHFR deficiency 19 0.441564506115428 1.07184473136442 0.363387978142077 0.581840866736157 0.438895732651063 841 tags=21%, list=7%, signal=20% 2906/1786/1789/1788
348 WP4483 Relationship between inflammation, COX-2 and EGFR 22 -0.464475347238321 -1.06287519048983 0.368992248062016 0.588205839125012 0.443696975361258 1407 tags=36%, list=11%, signal=32% 5293/5595/51365/5743/5734/10000/2099/5733
349 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 22 -0.463523354991416 -1.06069671331814 0.370542635658915 0.588205839125012 0.443696975361258 3131 tags=41%, list=26%, signal=31% 5595/6194/7249/5578/1432/6446/374/2308/627
350 WP4758 Nephrotic syndrome 33 -0.43316234442618 -1.06937203694902 0.371428571428571 0.588205839125012 0.443696975361258 911 tags=15%, list=7%, signal=14% 4000/3913/83478/1286/11346
351 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases 5 0.639653233439367 1.13706498012006 0.372246696035242 0.588205839125012 0.443696975361258 2267 tags=60%, list=18%, signal=49% 79017/26873/2937
352 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 3 0.72428600979135 1.11609455902724 0.37344398340249 0.588205839125012 0.443696975361258 2742 tags=67%, list=22%, signal=52% 7514/1984
353 WP4722 Glycerolipids and Glycerophospholipids 18 0.443478108165871 1.06500579859991 0.374005305039788 0.588205839125012 0.443696975361258 3552 tags=50%, list=29%, signal=36% 9791/5833/10400/54675/55500/1040/84649/8694/57678
354 WP1584 Type II diabetes mellitus 14 -0.529166050854214 -1.09061629425894 0.374795417348609 0.588205839125012 0.443696975361258 115 tags=50%, list=1%, signal=50% 3667/5594/6834/3551/3643/23533/6517
355 WP2289 Drug Induction of Bile Acid Pathway 4 -0.694765368114686 -1.12548146451017 0.380255941499086 0.592278244631186 0.446768882991793 2260 tags=50%, list=18%, signal=41% 10257/5243
356 WP143 Fatty Acid Beta Oxidation 27 -0.447716674075732 -1.06830995564207 0.382848392036753 0.592278244631186 0.446768882991793 3411 tags=48%, list=28%, signal=35% 3032/1632/57104/788/4023/1374/3033/3991/3030/1384/2182/34/38
357 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 17 -0.50186640453637 -1.07584676529054 0.384863123993559 0.592278244631186 0.446768882991793 4229 tags=59%, list=34%, signal=39% 5594/3397/4087/3371/5595/7040/4089/6615/1004/7431
358 WP727 Monoamine Transport 17 -0.501799752624678 -1.07570388415136 0.384863123993559 0.592278244631186 0.446768882991793 1949 tags=53%, list=16%, signal=45% 273/183/1432/60482/10497/114907/3690/5516/7041
359 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders 9 -0.578300887098258 -1.10183826027219 0.384873949579832 0.592278244631186 0.446768882991793 248 tags=44%, list=2%, signal=44% 27430/635/4548/1036
360 WP4479 Supression of HMGB1 mediated inflammation by THBD 9 -0.578147662384566 -1.10154632080654 0.384873949579832 0.592278244631186 0.446768882991793 2399 tags=67%, list=20%, signal=54% 7056/8517/3551/5970/4792/4790
361 WP698 Glucuronidation 9 -0.577466156342071 -1.1002478454817 0.384873949579832 0.592278244631186 0.446768882991793 71 tags=44%, list=1%, signal=44% 3098/5236/7360/5239
362 WP4495 IL-10 Anti-inflammatory Signaling Pathway 11 -0.557059455234525 -1.10026107435266 0.386776859504132 0.593557839793045 0.447734110579211 48 tags=27%, list=0%, signal=27% 3716/3587/3569
363 WP3971 Role of Osx and miRNAs in tooth development 10 -0.564283191145476 -1.09235960551768 0.387858347386172 0.593573271966683 0.447745751417012 3191 tags=50%, list=26%, signal=37% 4853/655/4855/22943/9314
364 WP3529 Zinc homeostasis 24 0.402638749574989 1.04161803021906 0.390532544378698 0.596019365250135 0.449590894935024 1824 tags=38%, list=15%, signal=32% 55630/55676/201266/7922/29985/148867/27173/57181/55334
365 WP690 Polyol Pathway 3 0.714075842567785 1.10036111680838 0.392116182572614 0.59679221193744 0.450173870680532 2353 tags=67%, list=19%, signal=54% 231/6652
366 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 55 -0.389979357081053 -1.03786936494655 0.393646408839779 0.597479754786952 0.450692499810792 1825 tags=16%, list=15%, signal=14% 6776/8536/1026/3725/4609/8322/58/8324/4638
367 WP3925 Amino Acid metabolism 66 -0.383941301514217 -1.05302299917537 0.395502645502646 0.59811834867102 0.451174205628719 2417 tags=26%, list=20%, signal=21% 384/2746/128/445/1743/8802/4967/50/216/151742/4942/34/501/4953/126/8639/5166
368 WP3580 Methionine De Novo and Salvage Pathway 19 -0.478745096628679 -1.05656757268741 0.39622641509434 0.59811834867102 0.451174205628719 1610 tags=26%, list=13%, signal=23% 22921/4144/4953/4482/253827
369 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 19 0.424824309717974 1.03120991796317 0.398907103825137 0.600528629128059 0.452992334721337 841 tags=21%, list=7%, signal=20% 1786/1789/6597/1788
370 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 16 -0.496436941953631 -1.05260950912558 0.406148867313916 0.608417584547305 0.458943152318601 3103 tags=44%, list=25%, signal=33% 8325/324/1452/27122/4035/6925/8324
371 WP561 Heme Biosynthesis 8 0.536905292600347 1.06598980362513 0.407766990291262 0.608417584547305 0.458943152318601 923 tags=25%, list=8%, signal=23% 3145/1371
372 WP528 Acetylcholine Synthesis 4 0.658824636227273 1.10386282601906 0.407894736842105 0.608417584547305 0.458943152318601 4091 tags=50%, list=33%, signal=33% 10400/5130
373 WP4216 Chromosomal and microsatellite instability in colorectal cancer 71 -0.372089318190405 -1.02956901010671 0.409271523178808 0.608417584547305 0.458943152318601 2761 tags=32%, list=23%, signal=25% 4089/1452/387/7042/8313/5900/842/1647/51426/83439/10912/1026/5743/3725/5602/7043/4609/10000/9423/4616/596/2353/7048
374 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation 24 -0.443481904805737 -1.04147754420425 0.409638554216867 0.608417584547305 0.458943152318601 2689 tags=33%, list=22%, signal=26% 650/6615/652/1432/1026/4882/7067/5745
375 WP2038 Regulation of Microtubule Cytoskeleton 42 0.348257037634053 1.02820961176323 0.410958904109589 0.608560606060606 0.459051036682616 700 tags=17%, list=6%, signal=16% 11004/983/9212/3984/3925/2048/2932
376 WP3965 Lipid Metabolism Pathway 26 0.382971929168465 1.02630159267562 0.411931818181818 0.608560606060606 0.459051036682616 485 tags=12%, list=4%, signal=11% 47/2194/29923
377 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 16 -0.491140684329963 -1.04137970194098 0.414239482200647 0.610342215795635 0.460394945223004 3285 tags=44%, list=27%, signal=32% 1632/788/1374/3033/3030/2182/34
378 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 3 -0.712133862471584 -1.09656268009355 0.415384615384615 0.610406039583758 0.460443088950698 3267 tags=100%, list=27%, signal=73% 2329/2327
379 WP3934 Leptin and adiponectin 8 -0.573487917528864 -1.06514996969126 0.422033898305085 0.618536454129675 0.466576044631352 601 tags=38%, list=5%, signal=36% 5564/1374/3953
380 WP2875 Constitutive Androstane Receptor Pathway 17 -0.489757470924579 -1.04988894675634 0.423510466988728 0.61906279343471 0.46697307428003 1104 tags=29%, list=9%, signal=27% 8648/1577/2308/5243/10891
381 WP4562 Canonical NF-KB pathway 8 -0.568421982425598 -1.05574091248748 0.430508474576271 0.627636039250669 0.473440067608808 2399 tags=50%, list=20%, signal=40% 3551/5970/4792/4790
382 WP75 Toll-like Receptor Signaling Pathway 78 -0.362702475922421 -1.01692564660777 0.432679738562092 0.628528292558029 0.474113114469955 3277 tags=36%, list=27%, signal=26% 929/7189/5293/5601/5606/5595/8503/148022/23533/7096/23118/6351/5970/54472/23643/4792/7100/8737/4790/1432/7098/7099/3725/5602/10000/1326/2353/3569
383 WP3630 NAD metabolism, sirtuins and aging 10 -0.542314954224904 -1.0498327059165 0.433389544688027 0.628528292558029 0.474113114469955 1683 tags=60%, list=14%, signal=52% 10135/2309/23410/4790/2308/23411
384 WP3601 Composition of Lipid Particles 4 -0.670261620451634 -1.08578674875219 0.435100548446069 0.629362151015986 0.474742112774741 2933 tags=75%, list=24%, signal=57% 3931/4023/3949
385 WP4673 Genes involved in male infertility 85 -0.355778128499587 -1.01129506019891 0.436477987421384 0.629710429769392 0.475004827319872 1950 tags=26%, list=16%, signal=22% 367/8476/472/6648/7057/9194/4780/355/6948/4846/340719/7320/8787/2099/143689/3983/4524/5243/596/2775/1191/6649
386 WP4147 PTF1A related regulatory pathway 5 -0.629330677952683 -1.06205177893462 0.445255474452555 0.640705280121339 0.483298491750278 1496 tags=60%, list=12%, signal=53% 4851/3516/8850
387 WP4148 Splicing factor NOVA regulated synaptic proteins 31 -0.409975035937273 -1.00224093328974 0.453030303030303 0.650204113675616 0.490463676855823 1120 tags=26%, list=9%, signal=24% 23136/54386/4134/2054/2037/5332/3778/57863
388 WP3874 Canonical and Non-Canonical TGF-B signaling 17 -0.476239325149383 -1.02091021203031 0.455716586151369 0.651829147716037 0.491689476806511 3811 tags=59%, list=31%, signal=41% 4087/4016/84171/5601/659/7040/4089/1432/657/7048
389 WP4189 Mevalonate arm of cholesterol biosynthesis pathway with inhibitors 2 0.739928233567118 1.06391770280984 0.456913827655311 0.651829147716037 0.491689476806511 3191 tags=100%, list=26%, signal=74% 4597/3156
390 WP733 Serotonin Receptor 2 and STAT3 Signaling 3 -0.674414811189952 -1.03848188076122 0.457692307692308 0.651829147716037 0.491689476806511 3996 tags=100%, list=33%, signal=67% 6774/3717
391 WP4504 Cysteine and methionine catabolism 13 -0.500665450554921 -1.01697870030491 0.46089850249584 0.654712231750501 0.493864252336973 248 tags=23%, list=2%, signal=23% 4548/6821/1036
392 WP3998 Prader-Willi and Angelman Syndrome 30 -0.411344389066711 -0.999611884307602 0.464339908952959 0.657913835191661 0.496279294263897 942 tags=20%, list=8%, signal=19% 5108/9638/4692/4487/627/894
393 WP3958 GPR40 Pathway 13 -0.499302365322767 -1.01420992797148 0.467554076539101 0.660777955108832 0.498439764731534 1720 tags=46%, list=14%, signal=40% 23236/113026/2767/5336/5310/5334
394 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 117 -0.338410169831958 -0.991921535958344 0.485257985257985 0.683281348745235 0.515414583796044 3310 tags=30%, list=27%, signal=22% 4216/10062/1977/5293/5601/5606/2309/5595/8503/7068/6655/5286/4023/9064/2889/7249/7786/23433/5170/57521/8660/1432/25759/5602/9252/5563/2308/4215/51422/7067/1326/6567/9020/6196/6517
395 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 64 0.309984767107206 0.989792867839255 0.485943775100402 0.683281348745235 0.515414583796044 2324 tags=22%, list=19%, signal=18% 47/2194/6319/7528/6713/2224/6720/10483/6396/2475/1622/51141/3837/4597
396 WP311 Synthesis and Degradation of Ketone Bodies 5 -0.605008519773591 -1.02100596269431 0.489051094890511 0.68406826307577 0.516008171083186 2248 tags=60%, list=18%, signal=49% 3158/5019/38
397 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 50 -0.381773624922786 -1.00088476159789 0.48951048951049 0.68406826307577 0.516008171083186 1745 tags=22%, list=14%, signal=19% 7057/4790/308/1026/8870/7185/4092/25/7431/9021/3727
398 WP619 Type II interferon signaling (IFNG) 31 0.342459121029187 0.95577436203706 0.491228070175439 0.68406826307577 0.516008171083186 2344 tags=29%, list=19%, signal=24% 5610/9636/2537/6773/3627/10379/6772/4938/4283
399 WP438 Non-homologous end joining 10 0.474872665082603 0.994288146872933 0.491442542787286 0.68406826307577 0.516008171083186 4169 tags=50%, list=34%, signal=33% 5591/7518/27434/64421/7520
400 WP4262 Breast cancer pathway 121 -0.333874367961316 -0.98422130077366 0.496332518337408 0.689143396388281 0.51983645898945 1881 tags=22%, list=15%, signal=19% 28514/5728/4855/1647/472/51426/83439/23493/81029/25759/10912/1026/6500/3725/4609/10000/2099/4616/3815/3479/2260/7482/8324/2252/2247/2353/5241
401 WP229 Irinotecan Pathway 7 -0.563966104721881 -1.00399818313346 0.507880910683012 0.702324456417485 0.529779230852634 2447 tags=57%, list=20%, signal=46% 1577/9429/8824/1066
402 WP268 Notch Signaling 40 0.324497795656443 0.953651114614969 0.508361204013378 0.702324456417485 0.529779230852634 1485 tags=18%, list=12%, signal=15% 2648/6868/3066/23385/151636/4854/51107
403 WP2324 AGE/RAGE pathway 63 -0.36423124058568 -0.987560696763441 0.51006711409396 0.70292831146282 0.530234732378377 3305 tags=38%, list=27%, signal=28% 3958/6774/5601/5595/4313/5321/4478/387/5970/6093/842/4303/5578/4792/6776/4790/1432/3725/3717/4846/2308/6777/3625/5579
404 WP4286 Genotoxicity pathway 49 -0.376474636301815 -0.978146277572307 0.513437057991513 0.705373058314235 0.532078860252235 1725 tags=43%, list=14%, signal=37% 84312/10210/11072/23002/91947/79671/10346/9209/9693/1647/6232/80271/1026/1263/5734/7832/1052/29950/3398/59/3708
405 WP3651 Pathways Affected in Adenoid Cystic Carcinoma 56 0.311216213099264 0.982447898682645 0.514492753623188 0.705373058314235 0.532078860252235 1134 tags=12%, list=9%, signal=11% 29128/672/1111/4602/11200/5591/4613
406 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 5 -0.593999882996221 -1.00242790400014 0.516423357664234 0.705373058314235 0.532078860252235 4229 tags=80%, list=34%, signal=52% 5594/6774/5595/3716
407 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway 19 -0.445557685887425 -0.983324541567945 0.517295597484277 0.705373058314235 0.532078860252235 1638 tags=32%, list=13%, signal=27% 5162/54583/6194/4780/8452/32
408 WP4357 NRF2-ARE regulation 22 0.371107876406758 0.951850833210632 0.518207282913165 0.705373058314235 0.532078860252235 1798 tags=27%, list=15%, signal=23% 192111/2048/2932/7965/2730/7525
409 WP2261 Signaling Pathways in Glioblastoma 80 0.284174568402245 0.950717137142876 0.521186440677966 0.707689431704885 0.533826153119589 917 tags=11%, list=7%, signal=10% 898/672/675/1869/1017/1019/5590/2956/4893
410 WP2272 Pathogenic Escherichia coli infection 47 -0.372620797969452 -0.969232106851218 0.523076923076923 0.708519842016175 0.534452550409313 2636 tags=34%, list=21%, signal=27% 387/9475/6093/3688/23643/5578/7846/347733/7280/7454/7100/60/7099/25/2534/84617
411 WP3938 miR-222 in Exercise-Induced Cardiac Growth 4 -0.626519846079316 -1.01492749390127 0.524680073126143 0.708957952468007 0.534783027037429 4508 tags=100%, list=37%, signal=63% 204851/28996/79618
412 WP2643 Nanoparticle-mediated activation of receptor signaling 28 -0.398351712590285 -0.955337128730705 0.526717557251908 0.709979383741015 0.535553515761321 2266 tags=25%, list=18%, signal=20% 3688/3672/1432/5602/374/7094/10000
413 WP2332 Interleukin-11 Signaling Pathway 40 -0.373929955938385 -0.955277136178694 0.529160739687055 0.711541382977254 0.536731767132757 1337 tags=18%, list=11%, signal=16% 2242/3717/2534/3590/596/9021/3572
414 WP1742 TP53 Network 18 -0.443422954343401 -0.962602077462073 0.5328 0.714700242130751 0.539114566076208 2012 tags=39%, list=16%, signal=33% 1647/472/666/1026/4609/25/596
415 WP2447 Amyotrophic lateral sclerosis (ALS) 30 -0.393197626468694 -0.955513265153361 0.541729893778452 0.724923577664885 0.546826259420406 1065 tags=17%, list=9%, signal=15% 1432/1471/5532/596/5533
416 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 56 -0.356753713667904 -0.950685389233134 0.544077134986226 0.726246124782019 0.547823886639676 1858 tags=21%, list=15%, signal=18% 1938/29904/23236/51719/84254/1026/5563/133522/51422/3953/32/6517
417 WP702 Metapathway biotransformation Phase I and II 90 -0.331884947921445 -0.946397988412624 0.545340050377834 0.726246124782019 0.547823886639676 2669 tags=21%, list=22%, signal=17% 1545/9420/2327/57016/1577/2052/285440/8514/9469/4837/113612/57404/7881/1593/51302/2053/11185/2949/2878
418 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 17 0.396598575627267 0.942682060912279 0.551181102362205 0.732264582035159 0.552363745141475 1014 tags=18%, list=8%, signal=16% 7472/7428/10631
419 WP1946 Cori Cycle 14 -0.456007027019577 -0.939834846096625 0.55810147299509 0.739533190404919 0.557846620921058 115 tags=14%, list=1%, signal=14% 3098/6517
420 WP254 Apoptosis 80 0.280738859164702 0.939222837463855 0.559322033898305 0.739533190404919 0.557846620921058 1927 tags=21%, list=16%, signal=18% 835/332/637/3070/1676/3663/7186/8718/1677/317/839/581/56616/3661/8772/27113/10018
421 WP1602 Nicotine Activity on Dopaminergic Neurons 11 -0.478741547452283 -0.945573554828799 0.563636363636364 0.743463203463203 0.560811118705856 1403 tags=55%, list=11%, signal=48% 2770/108/54331/6571/84152/3777
422 WP4685 Melanoma 63 -0.346530021316886 -0.939566383023237 0.566442953020134 0.743776084989639 0.561047132321654 3203 tags=38%, list=26%, signal=28% 5293/2113/5595/8503/6655/805/91860/808/801/5728/3791/1647/51426/8649/25759/80243/10912/1026/7414/10000/4286/4616/3815/2353
423 WP2583 T-Cell Receptor and Co-stimulatory Signaling 27 -0.389492100945826 -0.929378585113825 0.566615620214395 0.743776084989639 0.561047132321654 3626 tags=59%, list=30%, signal=42% 1859/926/7535/5133/805/5530/1452/801/5728/5578/4773/4792/940/3702/4790/2534
424 WP710 DNA Damage Response (only ATM dependent) 100 -0.324478661041044 -0.936286348383179 0.567901234567901 0.743776084989639 0.561047132321654 3203 tags=33%, list=26%, signal=25% 5293/5601/2309/8503/324/5934/6655/5286/896/7040/23533/847/4089/387/4791/5527/5728/472/6648/83439/81029/4790/3949/1026/3725/5602/8061/4609/25/10000/7482/596/894
425 WP205 IL-7 Signaling Pathway 25 -0.392890589566424 -0.926693469061768 0.569486404833837 0.744093085561192 0.561286253026398 3595 tags=44%, list=29%, signal=31% 3561/5295/6774/5595/2185/3716/6776/3574/4609/2534/6777
426 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus 15 -0.444386279064418 -0.928788809791323 0.579638752052545 0.752631818285169 0.567727212348873 2115 tags=33%, list=17%, signal=28% 2531/7357/64781/166929/256435
427 WP2854 Gene regulatory network modelling somitogenesis 6 0.489435363281967 0.915875388924504 0.579646017699115 0.752631818285169 0.567727212348873 1965 tags=33%, list=16%, signal=28% 2043/3280
428 WP4153 Degradation pathway of sphingolipids, including diseases 8 0.46703712510794 0.927271196877625 0.580097087378641 0.752631818285169 0.567727212348873 4395 tags=62%, list=36%, signal=40% 2717/2720/10825/4758/3073
429 WP3286 Copper homeostasis 47 -0.358460039965461 -0.932398249509891 0.586013986013986 0.755984072301015 0.570255893413459 1719 tags=19%, list=14%, signal=17% 4502/4137/5621/3725/4493/261729/2308/79689/6649
430 WP4150 Wnt Signaling in Kidney Disease 27 -0.383594467756489 -0.915306068686108 0.586523736600306 0.755984072301015 0.570255893413459 1730 tags=19%, list=14%, signal=16% 81029/5602/8322/7482/8324
431 WP4536 Genes related to primary cilium development (based on CRISPR) 95 0.274731147313717 0.94925630038194 0.588235294117647 0.755984072301015 0.570255893413459 2624 tags=22%, list=21%, signal=18% 163786/79867/79989/89891/11116/57560/51259/150737/23322/27077/79959/26005/10300/54903/90410/84314/255758/55125/79598/8481/9851
432 WP231 TNF alpha Signaling Pathway 88 -0.327383221507801 -0.931874255474766 0.588679245283019 0.755984072301015 0.570255893413459 1891 tags=18%, list=15%, signal=15% 4792/8737/7128/4790/8837/6500/3725/7185/7133/4215/6401/330/1326/6347/9020/3569
433 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway 32 -0.375012362210511 -0.921374057811769 0.591251885369532 0.755984072301015 0.570255893413459 2399 tags=22%, list=20%, signal=18% 5970/842/22900/4792/9744/22861/114548
434 WP106 Alanine and aspartate metabolism 7 0.469043983936996 0.904103867559653 0.591647331786543 0.755984072301015 0.570255893413459 621 tags=14%, list=5%, signal=14% 2571
435 WP288 NLR Proteins 8 0.456836936854127 0.90701940047428 0.592233009708738 0.755984072301015 0.570255893413459 654 tags=12%, list=5%, signal=12% 2048
436 WP4537 Hippo-Yap signaling pathway 23 -0.39246252720153 -0.911247991183471 0.597560975609756 0.759400894071044 0.572833279396171 1771 tags=22%, list=14%, signal=19% 11186/7005/7003/23043/26524
437 WP4533 Transcription co-factors SKI and SKIL protein partners 18 -0.421159708669777 -0.914272043289141 0.5984 0.759400894071044 0.572833279396171 1983 tags=28%, list=16%, signal=23% 6497/7005/4204/7003/26524
438 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 10 0.431076979671557 0.902588762826886 0.599022004889976 0.759400894071044 0.572833279396171 3510 tags=70%, list=29%, signal=50% 5590/84962/7335/3552/3654/92610/7334
439 WP4586 Metabolism of alpha-linolenic acid 6 0.478060227106553 0.894589212954575 0.603982300884956 0.76394108376773 0.576258047227415 2459 tags=50%, list=20%, signal=40% 246/3992/9415
440 WP699 Aflatoxin B1 metabolism 3 -0.597592161121822 -0.920188318988681 0.619230769230769 0.779215861294816 0.587780157579407 2384 tags=67%, list=19%, signal=54% 2944/2052
441 WP3924 Hfe effect on hepcidin production 4 -0.563536647726731 -0.912898196566318 0.619744058500914 0.779215861294816 0.587780157579407 1088 tags=75%, list=9%, signal=68% 3397/654/4092
442 WP237 Glucocorticoid and Mineralcorticoid Metabolism 2 -0.6428745272125 -0.92465908899689 0.620278330019881 0.779215861294816 0.587780157579407 1591 tags=100%, list=13%, signal=87% 3290
443 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 62 -0.331787423125432 -0.899655840084374 0.623497997329773 0.781488440092069 0.589494415193903 1720 tags=23%, list=14%, signal=20% 23236/1432/2770/3725/5908/3717/5906/108/54331/4609/5144/2775/1958/2353
444 WP3646 Hepatitis C and Hepatocellular Carcinoma 44 -0.344975408820757 -0.897234872231366 0.629009762900976 0.786617175275713 0.593363136204556 2231 tags=30%, list=18%, signal=24% 842/3716/960/4790/1432/1026/5743/3725/2487/4609/3570/330/3569
445 WP391 Mitochondrial Gene Expression 16 -0.419460147003083 -0.88939339948617 0.634304207119741 0.791451645820578 0.597009886739064 1861 tags=19%, list=15%, signal=16% 50804/133522/10891
446 WP4297 Thiamine metabolic pathways 8 -0.468836872681198 -0.870779602259688 0.638983050847458 0.79549800038088 0.600062143551604 1981 tags=38%, list=16%, signal=31% 10560/4967/27010
447 WP244 Alpha 6 Beta 4 signaling pathway 33 -0.361285764977268 -0.891926316739816 0.645112781954887 0.800617253710871 0.603923712185475 2636 tags=24%, list=21%, signal=19% 387/3915/5578/8660/1432/2549/3913/3908
448 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 5 -0.512767588583115 -0.865341145304311 0.645985401459854 0.800617253710871 0.603923712185475 4051 tags=80%, list=33%, signal=54% 9052/2550/693199/51704
449 WP3633 Caffeine and Theobromine metabolism 1 0.674957188289978 0.900912100245784 0.661764705882353 0.817689026461817 0.61680133670025 3987 tags=100%, list=33%, signal=67% 7498
450 WP4742 Ketogenesis and Ketolysis 8 -0.457744698085562 -0.850177896324434 0.66271186440678 0.817689026461817 0.61680133670025 3007 tags=38%, list=25%, signal=28% 788/5019/38
451 WP2889 Oxytocin signaling 2 -0.622166041428804 -0.894873666198628 0.667992047713718 0.821435487172678 0.619627376795655 4636 tags=100%, list=38%, signal=62% 2776
452 WP4228 Vitamin B6-dependent and responsive disorders 4 -0.531143599047165 -0.860423249568372 0.669104204753199 0.821435487172678 0.619627376795655 1856 tags=50%, list=15%, signal=42% 10157/501
453 WP4389 Bile Acids synthesis and enterohepatic circulation 5 -0.499086511662036 -0.842253104961129 0.671532846715328 0.821435487172678 0.619627376795655 4590 tags=80%, list=37%, signal=50% 2264/5594/5595/3949
454 WP4584 Biomarkers for pyrimidine metabolism disorders 12 0.388444767238018 0.852851352575445 0.671679197994987 0.821435487172678 0.619627376795655 1862 tags=42%, list=15%, signal=35% 6241/7298/80324/1890/7372
455 WP3930 EDA Signalling in Hair Follicle Development 9 -0.445264201303959 -0.84836309933393 0.673949579831933 0.822396623847777 0.620352383939896 1663 tags=56%, list=14%, signal=48% 4050/5727/1896/2735/22943
456 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) 10 -0.436647435816791 -0.845277740368078 0.676222596964587 0.823356744436002 0.621076624626815 1060 tags=30%, list=9%, signal=27% 4609/9021/3572
457 WP4539 Synaptic signaling pathways associated with autism spectrum disorder 39 -0.337278515533572 -0.86131472773095 0.681365576102418 0.827799406054254 0.624427824821468 3203 tags=41%, list=26%, signal=30% 5293/7337/5595/8503/1742/7249/8831/5728/57521/85358/5563/775/10000/4915/51422/627
458 WP3858 Toll-like Receptor Signaling related to MyD88 27 -0.354626754015956 -0.846185352900645 0.686064318529862 0.831481071191189 0.627204988149158 3725 tags=56%, list=30%, signal=39% 7187/5594/51284/114609/3551/7189/148022/7096/4791/5970/54472/7100/4790/7098/7099
459 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 14 -0.401734107105304 -0.827977838830255 0.687397708674304 0.831481071191189 0.627204988149158 1871 tags=43%, list=15%, signal=36% 7189/7096/7100/4790/7099/3725
460 WP3926 ApoE and miR-146 in inflammation and atherosclerosis 8 -0.439829238010611 -0.816903173052031 0.698305084745763 0.842137953579601 0.635243715696564 3220 tags=50%, list=26%, signal=37% 7189/4791/5970/7099
461 WP534 Glycolysis and Gluconeogenesis 33 -0.349405814527868 -0.862597620526027 0.699248120300752 0.842137953579601 0.635243715696564 787 tags=6%, list=6%, signal=6% 6515/6517
462 WP4220 Neurotransmitter Disorders 1 -0.64918861616244 -0.870112063601179 0.701520912547528 0.842280412128963 0.635351175404139 4304 tags=100%, list=35%, signal=65%
463 WP1495 Glycine Metabolism 3 0.564656300416955 0.870111828885615 0.703319502074689 0.842280412128963 0.635351175404139 161 tags=33%, list=1%, signal=33% 6472
464 WP581 EPO Receptor Signaling 25 -0.355405310621097 -0.838278617428573 0.70392749244713 0.842280412128963 0.635351175404139 2221 tags=28%, list=18%, signal=23% 6774/5595/5788/6776/8660/3717/6777
465 WP4661 Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension) 2 0.594586749437303 0.854936113915871 0.707414829659319 0.844628912998411 0.637122702755784 955 tags=50%, list=8%, signal=46% 84706
466 WP4566 Translation inhibitors in chronically activated PDGFRA cells 45 -0.326772283210191 -0.850829012276327 0.712100139082058 0.848394574304216 0.639963226294459 3254 tags=38%, list=27%, signal=28% 1977/5601/5606/5595/6194/8503/1974/5292/57521/5578/1432/5602/27250/1975/9252/10000/6196
467 WP3869 Cannabinoid receptor signaling 23 -0.35610173244223 -0.82682285786308 0.714939024390244 0.84905430664671 0.640460877329933 3336 tags=35%, list=27%, signal=25% 135/5601/5567/5595/5573/1432/5602/5577
468 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 40 0.288222726046106 0.84704404045395 0.71571906354515 0.84905430664671 0.640460877329933 2274 tags=28%, list=19%, signal=22% 4001/84823/1676/5591/1677/317/839/8772/5062/8767/836
469 WP422 MAPK Cascade 33 -0.34457466152478 -0.850670683676129 0.717293233082707 0.849103528050897 0.640498006148976 1744 tags=36%, list=14%, signal=31% 5606/5595/6655/4155/7786/8649/1432/3725/5602/22821/4215/6237
470 WP2828 Bladder Cancer 38 0.295652153465674 0.853433064626222 0.721854304635762 0.851150436959116 0.642042035859337 1317 tags=16%, list=11%, signal=14% 1869/1019/4312/4893/1890/4318
471 WP1604 Codeine and Morphine Metabolism 4 -0.502592805112083 -0.81417254271725 0.722120658135283 0.851150436959116 0.642042035859337 679 tags=25%, list=6%, signal=24% 5243
472 WP3303 RAC1/PAK1/p38/MMP2 Pathway 62 -0.30955130342258 -0.839361647004237 0.723631508678238 0.851150436959116 0.642042035859337 2399 tags=26%, list=20%, signal=21% 5970/3688/842/9046/4792/6776/4790/1432/2308/284/7010/4609/6777/10413/7075/9068
473 WP524 G13 Signaling Pathway 35 0.300015740922837 0.851575333280643 0.728971962616822 0.854866761462783 0.644845343531683 602 tags=11%, list=5%, signal=11% 11113/3984/6242/1072
474 WP61 Notch Signaling Pathway Netpath 57 -0.316513634190585 -0.847327214322279 0.72987721691678 0.854866761462783 0.644845343531683 2251 tags=40%, list=18%, signal=33% 5295/83464/55534/8650/9611/6774/4853/9612/84441/55294/7088/28514/4855/23493/4790/3516/1026/6015/4137/6500/3717/4609/2273
475 WP4655 Cytosolic DNA-sensing pathway 55 -0.316213084825049 -0.841551911854024 0.738950276243094 0.86366762244446 0.65148403213082 2466 tags=18%, list=20%, signal=15% 6351/5970/84265/4792/1540/8737/4790/54941/90865/3569
476 WP2507 Nanomaterial induced apoptosis 19 0.331158454597987 0.803847319908567 0.743169398907104 0.865393198250469 0.652785673010519 2274 tags=37%, list=19%, signal=30% 637/317/839/581/56616/8772/836
477 WP3676 BDNF-TrkB Signaling 30 -0.340250979753723 -0.82684711898177 0.743550834597876 0.865393198250469 0.652785673010519 1751 tags=23%, list=14%, signal=20% 1742/7249/29904/9846/2549/4915/627
478 WP4506 Tyrosine Metabolism 1 0.627252711408301 0.837237631399127 0.745798319327731 0.866189242992795 0.653386147573892 4572 tags=100%, list=37%, signal=63% 2184
479 WP4658 Small cell lung cancer 89 -0.299534904328356 -0.852629876475416 0.74968394437421 0.867432150313152 0.654323700692232 2399 tags=31%, list=20%, signal=25% 5970/3915/7188/3688/842/5728/1647/4792/2272/51426/4790/3910/10912/1026/5743/6500/7185/4609/1288/10000/3913/4616/1028/330/1286/596/10319/3908
480 WP585 Interferon type I signaling pathways 52 -0.31254966486388 -0.824157827280662 0.75 0.867432150313152 0.654323700692232 3524 tags=46%, list=29%, signal=33% 5295/7535/1398/6774/1977/5293/5606/8554/6194/2889/7409/5788/3716/57521/6776/8660/1432/9846/5906/27250/1975/9252/2534/9021
481 WP2059 Alzheimers Disease 69 -0.304595659022824 -0.84223421026692 0.754293262879789 0.869806763285024 0.656114924993644 1536 tags=19%, list=13%, signal=17% 23236/4035/355/4137/6622/775/489/5332/5532/322/6263/5533/3708
482 WP1772 Apoptosis Modulation and Signaling 79 -0.299443406685835 -0.842333733770823 0.755874673629243 0.869806763285024 0.656114924993644 2231 tags=25%, list=18%, signal=21% 842/54472/8738/4792/8737/4790/666/8837/355/5587/8793/3725/4170/9531/599/7133/330/596/9020/2353
483 WP4558 Overview of interferons-mediated signaling pathway 14 0.349355720319286 0.792137180046499 0.757033248081841 0.869806763285024 0.656114924993644 2081 tags=29%, list=17%, signal=24% 7297/6773/10379/6772
484 WP4205 MET in type 1 papillary renal cell carcinoma 52 -0.310138843898992 -0.817800767293892 0.758333333333333 0.869806763285024 0.656114924993644 1465 tags=33%, list=12%, signal=29% 5295/1398/6774/5293/2113/5595/8503/6655/2889/7030/1026/3725/5908/2549/5906/10000/3082
485 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells 18 -0.36314123798396 -0.788322992013622 0.76 0.869917355371901 0.656198347107438 3131 tags=33%, list=26%, signal=25% 5595/5869/22800/22808/6237/5873
486 WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma 7 -0.43315921984253 -0.771129800334142 0.763572679509632 0.870904389971442 0.656942889642148 2463 tags=43%, list=20%, signal=34% 7423/55662/7424
487 WP26 Signal Transduction of S1P Receptor 24 -0.339032448465089 -0.796187348360122 0.765060240963855 0.870904389971442 0.656942889642148 1720 tags=25%, list=14%, signal=22% 23236/1903/2770/9294/10000/1901
488 WP2878 PPAR Alpha Pathway 16 0.338857283807798 0.792631802422734 0.768229166666667 0.870904389971442 0.656942889642148 487 tags=12%, list=4%, signal=12% 983/1019
489 WP22 IL-9 Signaling Pathway 15 -0.37261138822411 -0.778775817543178 0.768472906403941 0.870904389971442 0.656942889642148 3595 tags=47%, list=29%, signal=33% 3561/5295/6774/5595/3716/6776/6777
490 WP691 Tamoxifen metabolism 5 0.408856097920705 0.726793716580559 0.768722466960352 0.870904389971442 0.656942889642148 937 tags=20%, list=8%, signal=18% 54575
491 WP2586 Aryl Hydrocarbon Receptor Netpath 40 -0.319424385397628 -0.816032006161509 0.772403982930299 0.871836837466952 0.657646255888999 3002 tags=40%, list=24%, signal=30% 57491/9612/405/4023/1545/5970/948/4790/4780/5325/1026/5743/135112/4609/2099/1316
492 WP1471 Target Of Rapamycin (TOR) Signaling 34 -0.322633578752431 -0.802786397434725 0.772795216741405 0.871836837466952 0.657646255888999 2564 tags=21%, list=21%, signal=16% 7249/57521/5578/58528/10670/5563/51422
493 WP4141 PI3K/AKT/mTOR - VitD3 Signalling 19 0.325936654269272 0.791172027639702 0.775956284153005 0.871836837466952 0.657646255888999 700 tags=11%, list=6%, signal=10% 5210/2932
494 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 20 -0.353255099266149 -0.788484357680968 0.776729559748428 0.871836837466952 0.657646255888999 1679 tags=25%, list=14%, signal=22% 666/4170/599/4609/596
495 WP3644 NAD+ metabolism 14 -0.369666930244778 -0.761887080478472 0.777414075286416 0.871836837466952 0.657646255888999 2913 tags=50%, list=24%, signal=38% 64802/10135/349565/23410/203447/4907/23411
496 WP3300 Dual hijack model of Vif in HIV infection 6 0.393335491018856 0.736044680954459 0.780973451327434 0.874059175829087 0.659322616006361 3874 tags=50%, list=32%, signal=34% 865/861/60489
497 WP2853 Endoderm Differentiation 112 -0.285082935557912 -0.832351189288985 0.784146341463415 0.875840873328088 0.660666590749099 1778 tags=28%, list=14%, signal=24% 4089/655/6001/58499/1846/1488/2736/79776/55809/23576/3915/5087/83439/23373/657/5090/57690/1844/57198/22943/2308/9760/83595/3087/1112/6925/2908/1847/2627/6422/64321
498 WP2369 Histone Modifications 30 0.293782338080948 0.808049187938813 0.790087463556851 0.880701116318905 0.664332782022811 2259 tags=30%, list=18%, signal=25% 2146/56950/9869/79723/6839/10322/55209/54093/10919
499 WP4156 Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases 2 -0.548523894960039 -0.788952717112593 0.799204771371769 0.888176352705411 0.669971521991351 5539 tags=100%, list=45%, signal=55% 2643
500 WP2533 Glycerophospholipid Biosynthetic Pathway 25 0.300461718808301 0.789449798660725 0.8 0.888176352705411 0.669971521991351 1962 tags=28%, list=16%, signal=24% 9791/9489/114971/5833/10400/54675/10390
501 WP4236 Disorders of the Krebs cycle 7 -0.408203612495765 -0.726702689865331 0.80385288966725 0.890669001751314 0.671851783574523 2454 tags=57%, list=20%, signal=46% 8803/8801/1743/8802
502 WP1531 Vitamin D Metabolism 7 0.367983239879823 0.709304631902429 0.807424593967517 0.892840768578852 0.673489996438921 409 tags=14%, list=3%, signal=14% 1717
503 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 16 -0.354703273062449 -0.7520875394047 0.812297734627832 0.896440129449838 0.676205075796287 1534 tags=25%, list=13%, signal=22% 3949/5465/23411/10891
504 WP4656 Joubert Syndrome 69 0.264259729226251 0.856645256448958 0.816326530612245 0.899095224570942 0.678207874130085 2083 tags=19%, list=17%, signal=16% 117177/261734/9094/79867/95681/51259/23322/27077/51524/79848/284086/54903/2475
505 WP1434 Osteopontin Signaling 13 0.324668896796456 0.730171807204141 0.820448877805486 0.901842615683015 0.680280293418501 1846 tags=31%, list=15%, signal=26% 6696/5328/4318/5604
506 WP107 Translation Factors 47 -0.298875767979579 -0.777412296533625 0.823776223776224 0.903706986083224 0.681686630201482 2455 tags=30%, list=20%, signal=24% 8666/9086/8661/1938/29904/2107/8665/10209/1975/1936/8637/1933/1979/1915
507 WP4549 Fragile X Syndrome 93 -0.285343976212467 -0.818070336810576 0.826899128268991 0.905135970429732 0.68276454543151 2758 tags=26%, list=22%, signal=20% 5530/1374/64798/1742/7249/1212/5573/8831/5728/57521/5578/8536/23236/1845/2549/26999/4204/2534/4915/1979/4131/1915/627/3708
508 WP4726 Sphingolipid Metabolism (integrated pathway) 21 -0.333054891894799 -0.750247495877166 0.828346456692913 0.905135970429732 0.68276454543151 2115 tags=33%, list=17%, signal=28% 259230/2531/7357/64781/79603/166929/6609
509 WP497 Urea cycle and metabolism of amino groups 16 0.313718055016933 0.733827836327903 0.830729166666667 0.905952673884514 0.683380603329189 691 tags=19%, list=6%, signal=18% 5831/162417/5832
510 WP4725 Sphingolipid Metabolism (general overview) 20 -0.33379024713508 -0.745037762113618 0.833333333333333 0.907007203667322 0.684176059008031 2115 tags=35%, list=17%, signal=29% 259230/2531/7357/64781/79603/166929/6609
511 WP3 Phytochemical activity on NRF2 transcriptional activation 14 0.319043257214972 0.723406005352206 0.838874680306905 0.911248182137305 0.68737512503992 2452 tags=29%, list=20%, signal=23% 2048/7965/2730/1728
512 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway 51 -0.293883067794566 -0.771758078218806 0.841004184100418 0.91177361642198 0.68777147201126 2893 tags=29%, list=24%, signal=23% 79671/9755/10010/5970/10521/4792/1540/8737/4790/1432/1654/5602/8653/54941/6387
513 WP400 p38 MAPK Signaling Pathway 33 -0.304011953252267 -0.750531263600248 0.84812030075188 0.917692669172932 0.692236347447566 2732 tags=24%, list=22%, signal=19% 5321/7042/9261/8737/1432/9252/4609/4209
514 WP4018 Pathways in clear cell renal cell carcinoma 79 0.25229560335728 0.842203228281442 0.851694915254237 0.919764099514322 0.69379887422988 2109 tags=18%, list=17%, signal=15% 47/6472/2194/2023/7428/7167/5723/29968/8242/5230/5232/2597/2475/2821
515 WP4255 Non-small cell lung cancer 67 -0.281011494924726 -0.774223659536101 0.855453350854139 0.92156868740922 0.695160115716246 3262 tags=34%, list=27%, signal=25% 6774/5293/2309/5595/8503/5915/6655/83593/6257/842/5578/1647/2272/6776/51426/11186/10912/1026/5336/10000/6777/4616/5579
516 WP2509 Nanoparticle triggered autophagic cell death 21 -0.320385420804169 -0.721707939212027 0.856692913385827 0.92156868740922 0.695160115716246 1266 tags=43%, list=10%, signal=38% 55626/115201/7248/3643/55054/51100/7249/84557/596
517 WP3645 NAD+ biosynthetic pathways 17 -0.333743557394139 -0.715443240299662 0.863123993558776 0.92668738843326 0.69902126773324 1101 tags=18%, list=9%, signal=16% 23410/683/23411
518 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 30 -0.303552256470985 -0.737665204976397 0.8649468892261 0.926848310698761 0.699142655039727 2564 tags=33%, list=21%, signal=26% 2309/8503/7249/2887/4303/5728/57521/4846/2308/7942
519 WP3871 Valproic acid pathway 8 -0.354117393758488 -0.657708941548915 0.874576271186441 0.935357633662719 0.705561429914686 4053 tags=62%, list=33%, signal=42% 3712/18/3032/3030/36
520 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 33 0.266889824586803 0.752958011527713 0.878338278931751 0.937571110844297 0.707231105843028 1694 tags=15%, list=14%, signal=13% 332/637/581/3486/5230
521 WP4263 Pancreatic adenocarcinoma pathway 85 0.248569587245435 0.826221845050004 0.884057971014493 0.941861761426979 0.71046764067359 487 tags=7%, list=4%, signal=7% 5888/5881/675/1869/1870/1019
522 WP4299 Lamin A-processing pathway 3 0.417859057608152 0.643903394973845 0.892116182572614 0.947497157489418 0.714718547450692 939 tags=33%, list=8%, signal=31% 23463
523 WP4159 GABA receptor Signaling 13 0.29198885062978 0.656675243152314 0.892768079800499 0.947497157489418 0.714718547450692 1844 tags=15%, list=15%, signal=13% 2571/1175
524 WP2249 Metastatic brain tumor 6 -0.363405157407161 -0.627512345181194 0.901818181818182 0.955272031983313 0.72058331122435 1060 tags=50%, list=9%, signal=46% 1021/5295/4609
525 WP1422 Sphingolipid pathway 24 -0.290934958053864 -0.683234698763713 0.903614457831325 0.955348109997241 0.720640698591877 2615 tags=33%, list=21%, signal=26% 259230/57704/2531/7357/64781/79603/166929/57515
526 WP694 Arylamine metabolism 2 -0.419262763007666 -0.603033886214071 0.914512922465209 0.965028874372811 0.727943118232958 7124 tags=100%, list=58%, signal=42% 6817
527 WP3655 Hypothetical Craniofacial Development Pathway 6 -0.335571088516203 -0.579449676037149 0.92 0.968973384030418 0.730918551130678 2636 tags=50%, list=21%, signal=39% 9411/387/7043
528 WP4271 Vitamin B12 Disorders 9 0.292736997164498 0.597017650972464 0.923832923832924 0.971164022397419 0.73257099922435 1425 tags=22%, list=12%, signal=20% 81693/25974
529 WP138 Androgen receptor signaling pathway 82 -0.262246132215985 -0.741717122527783 0.926829268292683 0.972468588322247 0.733555062823356 2761 tags=38%, list=23%, signal=29% 1387/9611/6774/7337/8554/7329/9612/9604/4089/2274/387/8648/573/9475/5970/6093/5728/8031/367/10273/10524/1026/3725/2308/8850/11034/7041/23411/2316/388/857
530 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 4 0.321451876019576 0.538593666326844 0.940789473684211 0.985250223858323 0.743196539752525 8323 tags=100%, list=68%, signal=32% 51/30/6342/3295
531 WP4523 Classical pathway of steroidogenesis, including diseases 5 -0.324685068678876 -0.547935079067982 0.950729927007299 0.991532536782858 0.747935430558226 3207 tags=60%, list=26%, signal=44% 1528/9563/3290
532 WP4313 Ferroptosis 36 0.246439549625049 0.702335430330283 0.950819672131147 0.991532536782858 0.747935430558226 2414 tags=22%, list=20%, signal=18% 7037/55240/246/4891/2730/6520/2937/10162
533 WP4674 Head and Neck Squamous Cell Carcinoma 66 -0.247363217128008 -0.678434843447439 0.953703703703704 0.991532536782858 0.747935430558226 3879 tags=36%, list=32%, signal=25% 7248/4851/79109/1021/5925/5295/8650/1977/2113/4853/5595/6194/23533/4089/7249/5728/5170/57521/2114/1026/2549/5563/10000/7048
534 WP3674 Tgif disruption of Shh signaling 4 0.31068515497553 0.520553990113917 0.953947368421053 0.991532536782858 0.747935430558226 8455 tags=100%, list=69%, signal=31% 60436/7050/2737/4087
535 WP521 Amino acid conjugation of benzoic acid 1 -0.520101117181766 -0.69709518171691 0.960076045627376 0.995450166514524 0.750890587319525 5887 tags=100%, list=48%, signal=52%
536 WP430 Statin Pathway 15 0.247713150522266 0.570326435355992 0.964376590330789 0.995450166514524 0.750890587319525 802 tags=13%, list=7%, signal=12% 341/6713
537 WP4582 Cancer immunotherapy by CTLA4 blockade 12 -0.26858911980456 -0.537859825787435 0.965174129353234 0.995450166514524 0.750890587319525 3937 tags=58%, list=32%, signal=40% 5781/5515/5295/5293/8503/3123/940
538 WP3891 Benzene metabolism 3 -0.325329253578636 -0.500950645681814 0.967307692307692 0.995450166514524 0.750890587319525 2384 tags=67%, list=19%, signal=54% 2944/2052
539 WP696 Benzo(a)pyrene metabolism 7 0.274612598012953 0.529328422166618 0.967517401392111 0.995450166514524 0.750890587319525 3553 tags=43%, list=29%, signal=30% 10327/1646/8644
540 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 6 0.281477462071131 0.526725895569096 0.971238938053097 0.995450166514524 0.750890587319525 2590 tags=33%, list=21%, signal=26% 29102/4683
541 WP2513 Nanoparticle triggered regulated necrosis 11 -0.256860765250472 -0.507331666086788 0.971900826446281 0.995450166514524 0.750890587319525 2885 tags=36%, list=24%, signal=28% 7132/148022/5321/8737
542 WP4723 Omega-3/Omega-6 FA synthesis 11 -0.254117966060651 -0.501914299672901 0.973553719008264 0.995450166514524 0.750890587319525 2732 tags=27%, list=22%, signal=21% 5321/10965/2182
543 WP3937 Microglia Pathogen Phagocytosis Pathway 36 0.219943316967631 0.626823025791755 0.977049180327869 0.995450166514524 0.750890587319525 2501 tags=22%, list=20%, signal=18% 5881/54209/1535/5777/7410/10451/5296/10095
544 WP4532 Intraflagellar transport proteins binding to dynein 25 0.220962266218544 0.580568523902844 0.979411764705882 0.995450166514524 0.750890587319525 1053 tags=8%, list=9%, signal=7% 89891/57560
545 WP692 Sulfation Biotransformation Reaction 6 -0.284059389786262 -0.490501497357131 0.98 0.995450166514524 0.750890587319525 8783 tags=100%, list=72%, signal=28% 9061/6799/2936/6817/9060
546 WP80 Nucleotide GPCRs 8 0.236572618706787 0.469699224116321 0.983009708737864 0.995450166514524 0.750890587319525 2570 tags=38%, list=21%, signal=30% 1241/5031/5029
547 WP4522 Metabolic pathway of LDL, HDL and TG, including diseases 9 -0.241517883499338 -0.460164683327411 0.984873949579832 0.995450166514524 0.750890587319525 3282 tags=44%, list=27%, signal=33% 19/3931/4023/3949
548 WP4751 HIPK2 in kidney fibrosis 2 0.337302234545751 0.484995439085364 0.985971943887776 0.995450166514524 0.750890587319525 8128 tags=100%, list=66%, signal=34% 6477/28996
549 WP697 Estrogen metabolism 9 0.217625458996328 0.44383266064857 0.987714987714988 0.995450166514524 0.750890587319525 9597 tags=100%, list=78%, signal=22% 1728/54578/1312/2944/414/412/6817/1543/1545
550 WP325 Triacylglyceride Synthesis 14 -0.233795918367347 -0.481855624885714 0.988543371522095 0.995450166514524 0.750890587319525 9401 tags=100%, list=77%, signal=23% 84649/55326/8694/8540/57678/56894/8443/2710/10554/57104/4023/3991/56895
551 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway 43 0.211381552734483 0.629128198155817 0.989690721649485 0.995450166514524 0.750890587319525 2083 tags=12%, list=17%, signal=10% 80347/23400/54676/26100/2475
552 WP4397 Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors 2 -0.315835186745099 -0.454271967058904 0.990059642147117 0.995450166514524 0.750890587319525 3197 tags=100%, list=26%, signal=74% 692094
553 WP3845 Canonical and Non-canonical Notch signaling 22 0.200290610067453 0.513723357000406 0.994397759103641 0.997218358831711 0.752224374798003 1965 tags=18%, list=16%, signal=15% 4237/102/4854/3280
554 WP623 Oxidative phosphorylation 37 -0.178982454914135 -0.455748830779194 0.997155049786629 0.997218358831711 0.752224374798003 4041 tags=27%, list=33%, signal=18% 126328/4700/4716/4719/4697/4705/4717/4698/4714/4724
555 WP4324 Mitochondrial complex I assembly model OXPHOS system 45 -0.188459502891383 -0.49069893910195 0.997218358831711 0.997218358831711 0.752224374798003 4160 tags=29%, list=34%, signal=19% 51103/55863/4700/4716/4719/4705/54968/4717/91942/29078/4698/4714/4724

503
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"set_id","name","GENE.SET","ES","NES","PVAL"
"WP289","Myometrial Relaxation and Contraction Pathways","WP289",-0.593,-1.73,0
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR","WP3414",-0.584,-1.75,0
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways","WP706",-0.521,-1.74,0
"WP98","Prostaglandin Synthesis and Regulation","WP98",-0.667,-1.65,0
"WP3981","miRNA regulation of prostate cancer signaling pathways","WP3981",-0.528,-1.76,0.00191
"WP536","Calcium Regulation in the Cardiac Cell","WP536",-0.561,-1.7,0.00192
"WP4321","Thermogenesis","WP4321",-0.404,-1.61,0.00197
"WP4589","Major receptors targeted by epinephrine and norepinephrine","WP4589",-0.807,-1.62,0.00198
"WP2858","Ectoderm Differentiation","WP2858",-0.476,-1.6,0.00374
"WP2516","ATM Signaling Pathway","WP2516",0.653,1.8,0.00383
"WP35","G Protein Signaling Pathways","WP35",-0.563,-1.6,0.00387
"WP4016","DNA IR-damage and cellular response via ATR","WP4016",0.71,1.74,0.00588
"WP170","Nuclear Receptors","WP170",-0.669,-1.6,0.00592
"WP4481","Resistin as a regulator of inflammation","WP4481",-0.572,-1.56,0.00758
"WP707","DNA Damage Response","WP707",0.53,1.64,0.00772
"WP1530","miRNA Regulation of DNA Damage Response","WP1530",0.526,1.64,0.00781
"WP531","DNA Mismatch Repair","WP531",0.775,1.6,0.00783
"WP383","Striated Muscle Contraction Pathway","WP383",-0.737,-1.57,0.00803
"WP304","Kit receptor signaling pathway","WP304",-0.479,-1.56,0.00949
"WP1971","Integrated Cancer Pathway","WP1971",0.553,1.61,0.0116
"WP2355","Corticotropin-releasing hormone signaling pathway","WP2355",-0.492,-1.56,0.0116
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism","WP4746",-0.393,-1.47,0.0133
"WP3888","VEGFA-VEGFR2 Signaling Pathway","WP3888",-0.366,-1.58,0.0134
"WP554","ACE Inhibitor Pathway","WP554",-0.805,-1.55,0.0134
"WP4149","White fat cell differentiation","WP4149",-0.615,-1.56,0.0135
"WP2276","Glial Cell Differentiation","WP2276",-0.861,-1.48,0.0143
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition","WP4240",0.826,1.58,0.0157
"WP2361","Gastric Cancer Network 1","WP2361",0.801,1.59,0.0158
"WP4223","Ras Signaling","WP4223",-0.428,-1.52,0.017
"WP247","Small Ligand GPCRs","WP247",-0.801,-1.44,0.0174
"WP382","MAPK Signaling Pathway","WP382",-0.414,-1.48,0.0174
"WP1591","Heart Development","WP1591",-0.614,-1.53,0.0192
"WP206","Fatty Acid Omega Oxidation","WP206",-0.862,-1.47,0.0195
"WP466","DNA Replication","WP466",0.807,1.58,0.0196
"WP2197","Endothelin Pathways","WP2197",-0.633,-1.52,0.0206
"WP1528","Physiological and Pathological Hypertrophy of the Heart","WP1528",-0.648,-1.51,0.0209
"WP428","Wnt Signaling","WP428",-0.453,-1.45,0.0209
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology","WP4535",-0.459,-1.59,0.0209
"WP3995","Prion disease pathway","WP3995",-0.538,-1.6,0.0213
"WP2338","miRNA Biogenesis","WP2338",0.739,1.62,0.0214
"WP3584","MECP2 and Associated Rett Syndrome","WP3584",-0.416,-1.5,0.0218
"WP236","Adipogenesis","WP236",-0.503,-1.5,0.0249
"WP179","Cell Cycle","WP179",0.57,1.73,0.0251
"WP4008","NO/cGMP/PKG mediated Neuroprotection","WP4008",-0.544,-1.56,0.0252
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM","WP3959",0.602,1.66,0.0257
"WP186","Homologous recombination","WP186",0.717,1.55,0.0282
"WP465","Tryptophan metabolism","WP465",-0.554,-1.57,0.0283
"WP1992","Genes targeted by miRNAs in adipocytes","WP1992",-0.742,-1.45,0.0291
"WP3634","Insulin signalling in human adipocytes (normal condition)","WP3634",-0.635,-1.56,0.0292
"WP3635","Insulin signalling in human adipocytes (diabetic condition)","WP3635",-0.635,-1.56,0.0292
"WP1544","MicroRNAs in cardiomyocyte hypertrophy","WP1544",-0.451,-1.47,0.033
"WP2446","Retinoblastoma Gene in Cancer","WP2446",0.705,1.65,0.0338
"WP3853","ERK Pathway in Huntington's Disease","WP3853",-0.564,-1.54,0.035
"WP410","Exercise-induced Circadian Regulation","WP410",-0.471,-1.48,0.035
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)","WP4719",-0.625,-1.47,0.0378
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome","WP4320",0.574,1.64,0.0383
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway","WP2035",-0.448,-1.5,0.0384
"WP167","Eicosanoid Synthesis","WP167",-0.672,-1.5,0.0402
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS","WP4304",-0.716,-1.46,0.0406
"WP3875","ATR Signaling","WP3875",0.771,1.48,0.0413
"WP4760","PKC-gamma calcium signaling pathway in ataxia","WP4760",-0.583,-1.39,0.0413
"WP4222","Phosphodiesterases in neuronal function","WP4222",-0.643,-1.49,0.0418
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy","WP2118",-0.505,-1.46,0.042
"WP45","G1 to S cell cycle control","WP45",0.596,1.65,0.0421
"WP2034","Leptin signaling pathway","WP2034",-0.384,-1.48,0.0427
"WP3996","Ethanol effects on histone modifications","WP3996",-0.456,-1.49,0.0427
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation","WP1991",-0.786,-1.38,0.043
"WP2848","Differentiation Pathway","WP2848",-0.632,-1.48,0.043
"WP2363","Gastric Cancer Network 2","WP2363",0.639,1.54,0.0437
"WP3893","Development and heterogeneity of the ILC family","WP3893",-0.714,-1.49,0.0437
"WP4753","Nucleotide Excision Repair","WP4753",0.554,1.62,0.0455
"WP4752","Base Excision Repair","WP4752",0.679,1.53,0.0466
"WP2895","Differentiation of white and brown adipocyte ","WP2895",-0.639,-1.46,0.0469
"WP2406","Cardiac Progenitor Differentiation","WP2406",-0.62,-1.45,0.047
"WP58","Monoamine GPCRs","WP58",-0.824,-1.38,0.0474
"WP2029","Cell Differentiation - Index","WP2029",-0.785,-1.35,0.0524
"WP4519","Cerebral Organic Acidurias, including diseases","WP4519",-0.657,-1.48,0.0542
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma","WP4336",-0.422,-1.43,0.0552
"WP4172","PI3K-Akt Signaling Pathway","WP4172",-0.398,-1.38,0.0565
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia","WP3658",-0.488,-1.45,0.0566
"WP4022","Pyrimidine metabolism","WP4022",0.528,1.56,0.057
"WP4155","Endometrial cancer","WP4155",-0.388,-1.4,0.0595
"WP2064","Neural Crest Differentiation","WP2064",-0.441,-1.39,0.0596
"WP2525","Trans-sulfuration and one carbon metabolism","WP2525",0.581,1.52,0.0603
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression","WP3879",0.45,1.48,0.0611
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)","WP2814",-0.667,-1.44,0.0655
"WP404","Nucleotide Metabolism","WP404",0.653,1.54,0.0663
"WP2795","Cardiac Hypertrophic Response","WP2795",-0.451,-1.44,0.0667
"WP4545","Oxysterols derived from cholesterol","WP4545",-0.676,-1.41,0.0686
"WP481","Insulin Signaling","WP481",-0.343,-1.37,0.0687
"WP4756","Renin Angiotensin Aldosterone System (RAAS)","WP4756",-0.498,-1.39,0.069
"WP241","One Carbon Metabolism","WP241",0.479,1.45,0.0696
"WP4595","Urea cycle and associated pathways","WP4595",0.565,1.44,0.07
"WP306","Focal Adhesion","WP306",-0.449,-1.43,0.0709
"WP3931","ESC Pluripotency Pathways","WP3931",-0.411,-1.38,0.0725
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway","WP3932",-0.397,-1.39,0.0725
"WP4191","Caloric restriction and aging","WP4191",-0.712,-1.43,0.0727
"WP4540","Pathways Regulating Hippo Signaling","WP4540",-0.449,-1.38,0.0775
"WP1545","miRNAs involved in DNA damage response","WP1545",0.485,1.4,0.0778
"WP49","IL-2 Signaling Pathway","WP49",-0.477,-1.42,0.0799
"WP4225","Pyrimidine metabolism and related diseases","WP4225",0.59,1.41,0.0805
"WP4290","Metabolic reprogramming in colon cancer","WP4290",0.554,1.57,0.0817
"WP673","ErbB Signaling Pathway","WP673",-0.361,-1.36,0.0821
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling","WP734",-0.53,-1.42,0.0821
"WP4754","IL-18 signaling pathway","WP4754",-0.375,-1.38,0.0832
"WP34","Ovarian Infertility Genes","WP34",-0.513,-1.41,0.0833
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma","WP4337",-0.611,-1.4,0.0835
"WP3594","Circadian rhythm related genes","WP3594",-0.341,-1.31,0.0842
"WP4521","Glycosylation and related congenital defects","WP4521",0.576,1.45,0.0853
"WP474","Endochondral Ossification","WP474",-0.506,-1.37,0.0857
"WP3599","Transcription factor regulation in adipogenesis","WP3599",-0.561,-1.39,0.0863
"WP3947","Serotonin and anxiety","WP3947",-0.731,-1.37,0.0867
"WP3298","Melatonin metabolism and effects","WP3298",-0.527,-1.36,0.0872
"WP3934","Leptin and adiponectin","WP3934",-0.574,-1.42,0.0874
"WP51","Regulation of Actin Cytoskeleton","WP51",-0.367,-1.34,0.088
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation","WP3876",-0.665,-1.4,0.0884
"WP2374","Oncostatin M Signaling Pathway","WP2374",-0.447,-1.42,0.0889
"WP1424","Globo Sphingolipid Metabolism","WP1424",-0.6,-1.37,0.0928
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk","WP3943",-0.755,-1.4,0.0932
"WP545","Complement Activation","WP545",-0.746,-1.39,0.0932
"WP185","Integrin-mediated Cell Adhesion","WP185",-0.377,-1.32,0.0934
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness","WP3301",-0.489,-1.32,0.0937
"WP3878","ATM Signaling Network in Development and Disease ","WP3878",0.458,1.46,0.0946
"WP3413","NOTCH1 regulation of human endothelial cell calcification","WP3413",-0.601,-1.39,0.095
"WP2059","Alzheimers Disease","WP2059",-0.298,-1.23,0.0986
"WP286","IL-3 Signaling Pathway","WP286",-0.457,-1.41,0.0994
"WP704","Methylation Pathways","WP704",-0.668,-1.36,0.1
"WP716","Vitamin A and Carotenoid Metabolism","WP716",-0.535,-1.38,0.1
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)","WP2813",-0.612,-1.37,0.101
"WP2636","Common Pathways Underlying Drug Addiction","WP2636",-0.497,-1.44,0.102
"WP1541","Energy Metabolism","WP1541",-0.475,-1.41,0.103
"WP2806","Human Complement System","WP2806",-0.583,-1.43,0.104
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement","WP4560",-0.634,-1.4,0.104
"WP1423","Ganglio Sphingolipid Metabolism","WP1423",-0.666,-1.34,0.106
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling","WP3679",-0.754,-1.35,0.108
"WP363","Wnt Signaling Pathway (Netpath)","WP363",-0.42,-1.37,0.109
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation","WP4767",-0.419,-1.31,0.113
"WP3935","Leptin Insulin Overlap","WP3935",-0.603,-1.34,0.114
"WP4698","Vitamin D-sensitive calcium signaling in depression","WP4698",-0.447,-1.27,0.114
"WP4507","Molybdenum cofactor (Moco) biosynthesis","WP4507",-0.615,-1.33,0.115
"WP3640","Imatinib and Chronic Myeloid Leukemia","WP3640",-0.537,-1.36,0.117
"WP3929","Chemokine signaling pathway","WP3929",-0.442,-1.38,0.117
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer","WP4258",-0.363,-1.26,0.117
"WP4666","Hepatitis B infection","WP4666",-0.322,-1.31,0.119
"WP3591","Sleep regulation","WP3591",-0.6,-1.39,0.12
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ","WP3595",0.591,1.35,0.121
"WP28","Selenium Metabolism and Selenoproteins","WP28",-0.387,-1.32,0.122
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma","WP4553",0.494,1.33,0.122
"WP3287","Overview of nanoparticle effects","WP3287",-0.534,-1.3,0.123
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway","WP2380",-0.341,-1.3,0.127
"WP2267","Synaptic Vesicle Pathway","WP2267",-0.488,-1.37,0.128
"WP2855","Dopaminergic Neurogenesis","WP2855",-0.712,-1.36,0.128
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling","WP732",-0.421,-1.32,0.131
"WP4249","Hedgehog Signaling Pathway","WP4249",-0.561,-1.36,0.132
"WP4747","Netrin-UNC5B signaling Pathway","WP4747",-0.426,-1.33,0.132
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ","WP3849",-0.477,-1.3,0.134
"WP2023","Cell Differentiation - Index expanded","WP2023",-0.561,-1.29,0.138
"WP3299","let-7 inhibition of ES cell reprogramming","WP3299",-0.737,-1.34,0.139
"WP4482","Vitamin D in inflammatory diseases","WP4482",-0.477,-1.33,0.14
"WP1601","Fluoropyrimidine Activity","WP1601",0.506,1.29,0.144
"WP2849","Hematopoietic Stem Cell Differentiation","WP2849",-0.533,-1.33,0.146
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance","WP3672",-0.67,-1.32,0.146
"WP4659","Gastrin Signaling Pathway","WP4659",-0.344,-1.3,0.147
"WP2879","Farnesoid X Receptor Pathway","WP2879",-0.73,-1.31,0.148
"WP2881","Estrogen Receptor Pathway","WP2881",-0.614,-1.32,0.149
"WP2882","Nuclear Receptors Meta-Pathway","WP2882",-0.385,-1.26,0.15
"WP364","IL-6 signaling pathway","WP364",-0.394,-1.34,0.15
"WP411","mRNA Processing","WP411",0.338,1.46,0.152
"WP2037","Prolactin Signaling Pathway","WP2037",-0.313,-1.25,0.153
"WP2431","Spinal Cord Injury","WP2431",-0.426,-1.26,0.155
"WP395","IL-4 Signaling Pathway","WP395",-0.39,-1.28,0.16
"WP3585","Cytosine methylation","WP3585",0.581,1.35,0.161
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity","WP3969",0.53,1.3,0.161
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses","WP1589",-0.568,-1.28,0.168
"WP1559","TFs Regulate miRNAs related to cardiac hypertrophy","WP1559",-0.569,-1.32,0.171
"WP405","Eukaryotic Transcription Initiation","WP405",0.392,1.34,0.176
"WP4352","Ciliary landscape","WP4352",0.26,1.25,0.177
"WP558","Complement and Coagulation Cascades","WP558",-0.583,-1.32,0.18
"WP23","B Cell Receptor Signaling Pathway","WP23",-0.393,-1.3,0.181
"WP530","Cytokines and Inflammatory Response","WP530",-0.655,-1.29,0.181
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)","WP2840",-0.447,-1.24,0.182
"WP3407","FTO Obesity Variant Mechanism","WP3407",-0.613,-1.26,0.182
"WP3930","EDA Signalling in Hair Follicle Development","WP3930",-0.617,-1.28,0.182
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS","WP2572",-0.408,-1.27,0.186
"WP2456","HIF1A and PPARG regulation of glycolysis","WP2456",0.689,1.31,0.188
"WP3892","Development of pulmonary dendritic cells and macrophage subsets","WP3892",-0.708,-1.26,0.191
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ","WP4216",-0.345,-1.24,0.194
"WP262","EBV LMP1 signaling","WP262",-0.449,-1.26,0.197
"WP2332","Interleukin-11 Signaling Pathway","WP2332",-0.331,-1.21,0.198
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ","WP2916",0.405,1.27,0.198
"WP4571","Urea cycle and related diseases","WP4571",0.701,1.24,0.198
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B","WP3656",0.567,1.28,0.199
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms","WP4534",-0.341,-1.18,0.199
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment","WP4480",-0.549,-1.26,0.208
"WP2290","RalA downstream regulated genes","WP2290",0.514,1.23,0.21
"WP4211","Transcriptional cascade regulating adipogenesis","WP4211",-0.559,-1.25,0.211
"WP183","Proteasome Degradation","WP183",0.445,1.33,0.212
"WP24","Peptide GPCRs","WP24",-0.631,-1.27,0.215
"WP3927","BMP Signaling Pathway in Eyelid Development","WP3927",-0.493,-1.23,0.216
"WP4312","Rett syndrome causing genes","WP4312",-0.37,-1.21,0.218
"WP4792","Purine metabolism","WP4792",0.618,1.28,0.22
"WP2112","IL17 signaling pathway","WP2112",-0.357,-1.21,0.221
"WP1539","Angiogenesis","WP1539",-0.526,-1.27,0.224
"WP2113","Type III interferon signaling","WP2113",0.583,1.25,0.224
"WP322","Osteoblast Signaling","WP322",-0.706,-1.26,0.229
"WP4538","Regulatory circuits of the STAT3 signaling pathway","WP4538",-0.406,-1.22,0.23
"WP3963","Mevalonate pathway","WP3963",0.715,1.24,0.233
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway","WP2036",-0.386,-1.24,0.234
"WP4724","Omega-9 FA synthesis","WP4724",0.565,1.26,0.237
"WP4541","Hippo-Merlin Signaling Dysregulation","WP4541",-0.376,-1.18,0.241
"WP438","Non-homologous end joining","WP438",0.473,1.25,0.242
"WP4396","Nonalcoholic fatty liver disease","WP4396",-0.284,-1.21,0.242
"WP1602","Nicotine Activity on Dopaminergic Neurons","WP1602",-0.511,-1.19,0.244
"WP127","IL-5 Signaling Pathway","WP127",-0.372,-1.2,0.248
"WP1533","Vitamin B12 Metabolism","WP1533",-0.473,-1.23,0.25
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway","WP69",-0.433,-1.23,0.251
"WP3933","Kennedy pathway from Sphingolipids","WP3933",0.506,1.22,0.252
"WP3944","Serotonin and anxiety-related events","WP3944",-0.635,-1.2,0.252
"WP1984","Integrated Breast Cancer Pathway","WP1984",0.27,1.13,0.254
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)","WP4718",0.445,1.24,0.254
"WP4685","Melanoma","WP4685",-0.295,-1.15,0.255
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway","WP2018",-0.366,-1.19,0.256
"WP2333","Trans-sulfuration pathway","WP2333",0.537,1.22,0.256
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway","WP3670",-0.428,-1.18,0.256
"WP4331","Neovascularisation processes","WP4331",-0.438,-1.2,0.256
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway","WP2203",-0.423,-1.21,0.257
"WP4483","Relationship between inflammation, COX-2 and EGFR","WP4483",-0.398,-1.16,0.257
"WP15","Selenium Micronutrient Network","WP15",-0.393,-1.17,0.259
"WP3965","Lipid Metabolism Pathway","WP3965",-0.414,-1.19,0.259
"WP134","Pentose Phosphate Metabolism","WP134",0.659,1.23,0.26
"WP408","Oxidative Stress","WP408",-0.45,-1.19,0.263
"WP143","Fatty Acid Beta Oxidation","WP143",-0.377,-1.19,0.264
"WP455","GPCRs, Class A Rhodopsin-like","WP455",-0.481,-1.19,0.264
"WP2870","Extracellular vesicle-mediated signaling in recipient cells","WP2870",-0.366,-1.13,0.265
"WP2485","NAD Biosynthesis II (from tryptophan)","WP2485",-0.587,-1.18,0.266
"WP3958","GPR40 Pathway","WP3958",-0.499,-1.17,0.266
"WP4298","Viral Acute Myocarditis","WP4298",-0.357,-1.16,0.266
"WP712","Estrogen signaling pathway","WP712",-0.436,-1.2,0.266
"WP3527","Preimplantation Embryo","WP3527",-0.413,-1.15,0.267
"WP4259","Disorders of Folate Metabolism and Transport","WP4259",0.47,1.16,0.273
"WP4153","Degradation pathway of sphingolipids, including diseases","WP4153",0.505,1.18,0.274
"WP4241","Type 2 papillary renal cell carcinoma","WP4241",-0.375,-1.16,0.274
"WP2637","Structural Pathway of Interleukin 1 (IL-1)","WP2637",-0.341,-1.16,0.277
"WP197","Cholesterol Biosynthesis Pathway","WP197",0.661,1.24,0.278
"WP313","Signaling of Hepatocyte Growth Factor Receptor","WP313",-0.379,-1.19,0.278
"WP561","Heme Biosynthesis","WP561",0.528,1.19,0.281
"WP2272","Pathogenic Escherichia coli infection","WP2272",-0.319,-1.14,0.282
"WP3580","Methionine De Novo and Salvage Pathway","WP3580",-0.415,-1.15,0.282
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1","WP4269",-0.519,-1.17,0.282
"WP4493","Cells and Molecules involved in local acute inflammatory response ","WP4493",-0.65,-1.22,0.282
"WP4586","Metabolism of alpha-linolenic acid","WP4586",0.576,1.15,0.285
"WP3596","miR-517 relationship with ARCN1 and USP1","WP3596",-0.599,-1.19,0.286
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex","WP3657",0.324,1.11,0.287
"WP2805","exRNA mechanism of action and biogenesis","WP2805",0.571,1.2,0.29
"WP2007","Iron metabolism in placenta","WP2007",0.518,1.17,0.295
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells","WP4301",-0.346,-1.12,0.297
"WP47","Hedgehog Signaling Pathway Netpath","WP47",-0.591,-1.19,0.302
"WP4462","Platelet-mediated interactions with vascular and circulating cells","WP4462",-0.601,-1.18,0.303
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway","WP4136",-0.439,-1.15,0.309
"WP516","Hypertrophy Model","WP516",-0.482,-1.13,0.309
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells","WP4300",-0.426,-1.1,0.314
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection","WP3863",-0.393,-1.15,0.318
"WP205","IL-7 Signaling Pathway","WP205",-0.402,-1.17,0.32
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging","WP4186",-0.599,-1.18,0.321
"WP4217","Ebola Virus Pathway on Host","WP4217",-0.343,-1.13,0.321
"WP117","GPCRs, Other","WP117",-0.459,-1.12,0.322
"WP422","MAPK Cascade","WP422",-0.299,-1.09,0.323
"WP4496","Signal transduction through IL1R","WP4496",-0.404,-1.13,0.325
"WP4585","Cancer immunotherapy by PD-1 blockade","WP4585",-0.556,-1.18,0.329
"WP176","Folate Metabolism","WP176",-0.349,-1.08,0.33
"WP4584","Biomarkers for pyrimidine metabolism disorders","WP4584",0.455,1.12,0.33
"WP2874","Liver X Receptor Pathway","WP2874",0.643,1.16,0.333
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway","WP3915",-0.259,-1.08,0.334
"WP399","Wnt Signaling Pathway and Pluripotency","WP399",-0.304,-1.06,0.335
"WP4389","Bile Acids synthesis and enterohepatic circulation ","WP4389",-0.571,-1.15,0.336
"WP4255","Non-small cell lung cancer","WP4255",-0.256,-1.05,0.338
"WP3851","TLR4 Signaling and Tolerance","WP3851",-0.371,-1.11,0.339
"WP53","ID signaling pathway","WP53",0.455,1.09,0.339
"WP4288","MTHFR deficiency","WP4288",0.371,1.09,0.342
"WP3972","PDGFR-beta pathway","WP3972",-0.395,-1.13,0.346
"WP727","Monoamine Transport","WP727",-0.423,-1.09,0.35
"WP3624","Lung fibrosis","WP3624",-0.434,-1.08,0.357
"WP4657","22q11.2 Deletion Syndrome","WP4657",-0.344,-1.08,0.358
"WP3644","NAD+ metabolism","WP3644",-0.394,-1.08,0.359
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment","WP4559",-0.497,-1.14,0.36
"WP560","TGF-beta Receptor Signaling","WP560",-0.378,-1.1,0.36
"WP3998","Prader-Willi and Angelman Syndrome","WP3998",-0.341,-1.05,0.361
"WP500","Glycogen Synthesis and Degradation","WP500",-0.335,-1.08,0.361
"WP4583","Biomarkers for urea cycle disorders","WP4583",-0.531,-1.09,0.366
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase","WP678",-0.587,-1.12,0.366
"WP4148","Splicing factor NOVA regulated synaptic proteins","WP4148",-0.356,-1.06,0.367
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder","WP4539",-0.36,-1.09,0.37
"WP2328","Allograft Rejection","WP2328",-0.491,-1.13,0.374
"WP4286","Genotoxicity pathway","WP4286",-0.329,-1.04,0.377
"WP4210","Tryptophan catabolism leading to NAD+ production","WP4210",-0.434,-1.04,0.379
"WP4262","Breast cancer pathway","WP4262",-0.275,-1.05,0.381
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling","WP1403",-0.299,-1.06,0.383
"WP2369","Histone Modifications","WP2369",0.324,1.04,0.384
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling","WP3850",-0.341,-1.05,0.385
"WP3940","One carbon metabolism and related pathways","WP3940",-0.339,-1.03,0.385
"WP4494","Selective expression of chemokine receptors during T-cell polarization","WP4494",-0.557,-1.13,0.389
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation","WP314",0.286,1.06,0.392
"WP136","Phase I biotransformations, non P450","WP136",-0.557,-1.1,0.393
"WP4565","Neural Crest Cell Migration in Cancer","WP4565",-0.339,-1.05,0.393
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders","WP4292",-0.476,-1.05,0.398
"WP4479","Supression of HMGB1 mediated inflammation by THBD","WP4479",-0.422,-1.05,0.402
"WP1584","Type II diabetes mellitus","WP1584",-0.362,-1.03,0.406
"WP2371","Parkinsons Disease Pathway","WP2371",0.325,1.05,0.407
"WP2877","Vitamin D Receptor Pathway","WP2877",-0.348,-1.04,0.407
"WP3300","Dual hijack model of Vif in HIV infection","WP3300",0.506,1.07,0.407
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus","WP4142",-0.397,-1.03,0.411
"WP3941","Oxidative Damage","WP3941",-0.375,-1.06,0.413
"WP437","EGF/EGFR Signaling Pathway","WP437",-0.239,-1.02,0.415
"WP4239","Epithelial to mesenchymal transition in colorectal cancer","WP4239",-0.29,-1.03,0.417
"WP4224","Purine metabolism and related disorders","WP4224",0.377,1.05,0.419
"WP4197","The human immune response to tuberculosis","WP4197",0.435,1.08,0.421
"WP391","Mitochondrial Gene Expression","WP391",-0.372,-1.06,0.422
"WP4722","Glycerolipids and Glycerophospholipids","WP4722",0.368,1.03,0.422
"WP4658","Small cell lung cancer","WP4658",-0.276,-1.01,0.423
"WP3303","RAC1/PAK1/p38/MMP2 Pathway","WP3303",0.257,1.02,0.426
"WP3613","Photodynamic therapy-induced unfolded protein response","WP3613",0.34,1,0.433
"WP366","TGF-beta Signaling Pathway","WP366",-0.28,-1.02,0.434
"WP1455","Serotonin Transporter Activity","WP1455",-0.465,-1.02,0.439
"WP2509","Nanoparticle triggered autophagic cell death","WP2509",-0.322,-0.999,0.439
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing","WP4705",0.426,1.03,0.441
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway","WP4206",-0.313,-1.02,0.445
"WP2857","Mesodermal Commitment Pathway","WP2857",-0.306,-1,0.447
"WP698","Glucuronidation","WP698",-0.409,-1.01,0.447
"WP272","Blood Clotting Cascade","WP272",-0.435,-0.996,0.448
"WP195","IL-1 signaling pathway","WP195",-0.278,-1.01,0.45
"WP2324","AGE/RAGE pathway","WP2324",-0.275,-1.01,0.451
"WP4673","Genes involved in male infertility","WP4673",-0.254,-0.991,0.461
"WP129","Matrix Metalloproteinases","WP129",0.414,1,0.463
"WP61","Notch Signaling Pathway Netpath","WP61",-0.264,-0.992,0.465
"WP2436","Dopamine metabolism","WP2436",-0.44,-0.996,0.466
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways","WP3680",-0.301,-1.01,0.466
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity","WP299",-0.475,-1.04,0.469
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)","WP2817",-0.386,-0.992,0.472
"WP2884","NRF2 pathway","WP2884",-0.303,-0.962,0.473
"WP1449","Regulation of toll-like receptor signaling pathway","WP1449",-0.277,-0.979,0.477
"WP2865","IL1 and megakaryocytes in obesity","WP2865",-0.45,-1.01,0.48
"WP3630","NAD metabolism, sirtuins and aging","WP3630",-0.418,-0.976,0.484
"WP585","Interferon type I signaling pathways","WP585",-0.262,-0.964,0.485
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions","WP4542",-0.37,-1.01,0.488
"WP1434","Osteopontin Signaling","WP1434",0.388,0.984,0.492
"WP4564","Neural Crest Cell Migration during Development","WP4564",-0.322,-0.997,0.494
"WP78","TCA Cycle (aka Krebs or citric acid cycle)","WP78",-0.371,-0.991,0.5
"WP2876","Pregnane X Receptor pathway","WP2876",-0.414,-0.967,0.502
"WP4726","Sphingolipid Metabolism (integrated pathway)","WP4726",-0.334,-0.965,0.502
"WP3676","BDNF-TrkB Signaling","WP3676",-0.304,-0.973,0.504
"WP26","Signal Transduction of S1P Receptor","WP26",-0.311,-0.971,0.508
"WP4150","Wnt Signaling in Kidney Disease","WP4150",-0.336,-0.951,0.509
"WP4504","Cysteine and methionine catabolism","WP4504",-0.38,-0.935,0.513
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma","WP3651",0.262,0.969,0.516
"WP229","Irinotecan Pathway","WP229",-0.521,-0.964,0.523
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3","WP4341",-0.285,-0.944,0.523
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease","WP3668",-0.379,-0.944,0.526
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds","WP3664",-0.399,-0.973,0.527
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases","WP4518",0.542,0.979,0.527
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)","WP4721",-0.378,-0.93,0.533
"WP501","GPCRs, Class C Metabotropic glutamate, pheromone","WP501",-0.575,-0.97,0.533
"WP4725","Sphingolipid Metabolism (general overview)","WP4725",-0.335,-0.937,0.534
"WP3945","TYROBP Causal Network","WP3945",-0.435,-0.974,0.535
"WP3845","Canonical and Non-canonical Notch signaling","WP3845",0.325,0.923,0.536
"WP4146","Macrophage markers","WP4146",-0.564,-0.992,0.536
"WP4297","Thiamine metabolic pathways","WP4297",-0.382,-0.913,0.536
"WP2583","T-Cell Receptor and Co-stimulatory Signaling","WP2583",-0.337,-0.914,0.539
"WP3967","miR-509-3p alteration of YAP1/ECM axis","WP3967",-0.467,-0.965,0.542
"WP3971","Role of Osx and miRNAs in tooth development","WP3971",-0.442,-0.939,0.543
"WP4566","Translation inhibitors in chronically activated PDGFRA cells","WP4566",-0.244,-0.935,0.545
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation","WP1425",-0.436,-0.943,0.55
"WP453","Inflammatory Response Pathway","WP453",-0.418,-0.94,0.551
"WP4561","Cell migration and invasion through p75NTR","WP4561",-0.322,-0.906,0.552
"WP22","IL-9 Signaling Pathway","WP22",-0.308,-0.905,0.554
"WP3982","miRNA regulation of p53 pathway in prostate cancer","WP3982",0.364,0.941,0.558
"WP4656","Joubert Syndrome","WP4656",0.288,0.9,0.563
"WP288","NLR Proteins","WP288",0.405,0.94,0.567
"WP311","Synthesis and Degradation of Ketone Bodies","WP311",-0.466,-0.927,0.569
"WP2875","Constitutive Androstane Receptor Pathway","WP2875",-0.356,-0.905,0.573
"WP1946","Cori Cycle","WP1946",-0.359,-0.886,0.58
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway","WP2032",-0.242,-0.93,0.58
"WP4204","Tumor suppressor activity of SMARCB1","WP4204",0.295,0.893,0.589
"WP1742","TP53 Network","WP1742",-0.333,-0.904,0.59
"WP4758","Nephrotic syndrome","WP4758",-0.27,-0.922,0.594
"WP2911","miRNA targets in ECM and membrane receptors","WP2911",-0.47,-0.937,0.596
"WP2873","Aryl Hydrocarbon Receptor Pathway","WP2873",-0.307,-0.892,0.599
"WP4313","Ferroptosis","WP4313",0.289,0.879,0.606
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ","WP4495",-0.362,-0.879,0.617
"WP3942","PPAR signaling pathway","WP3942",-0.292,-0.906,0.618
"WP3617","Photodynamic therapy-induced NF-kB survival signaling","WP3617",-0.361,-0.873,0.619
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.","WP3611",-0.267,-0.895,0.622
"WP384","Apoptosis Modulation by HSP70","WP384",0.318,0.853,0.626
"WP4205","MET in type 1 papillary renal cell carcinoma","WP4205",-0.218,-0.869,0.627
"WP4357","NRF2-ARE regulation","WP4357",0.316,0.862,0.631
"WP581","EPO Receptor Signaling","WP581",-0.272,-0.869,0.634
"WP477","Cytoplasmic Ribosomal Proteins","WP477",-0.308,-0.853,0.64
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities","WP3844",-0.261,-0.869,0.641
"WP702","Metapathway biotransformation Phase I and II","WP702",-0.293,-0.878,0.643
"WP254","Apoptosis","WP254",0.276,0.863,0.645
"WP4271","Vitamin B12 Disorders","WP4271",0.357,0.859,0.651
"WP3","Phytochemical activity on NRF2 transcriptional activation","WP3",0.378,0.847,0.654
"WP4532","Intraflagellar transport proteins binding to dynein","WP4532",-0.285,-0.813,0.654
"WP3858","Toll-like Receptor Signaling related to MyD88","WP3858",-0.309,-0.84,0.655
"WP43","Oxidation by Cytochrome P450","WP43",-0.341,-0.849,0.655
"WP75","Toll-like Receptor Signaling Pathway","WP75",-0.248,-0.846,0.66
"WP2526","PDGF Pathway","WP2526",-0.25,-0.854,0.661
"WP2586","Aryl Hydrocarbon Receptor Netpath","WP2586",-0.267,-0.852,0.662
"WP619","Type II interferon signaling (IFNG)","WP619",0.354,0.788,0.664
"WP2038","Regulation of Microtubule Cytoskeleton","WP2038",0.266,0.817,0.68
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)","WP2815",0.385,0.834,0.689
"WP244","Alpha 6 Beta 4 signaling pathway","WP244",-0.25,-0.793,0.692
"WP3646","Hepatitis C and Hepatocellular Carcinoma","WP3646",0.255,0.824,0.696
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer","WP2291",-0.393,-0.794,0.704
"WP4533","Transcription co-factors SKI and SKIL protein partners","WP4533",-0.308,-0.829,0.705
"WP615","Senescence and Autophagy in Cancer","WP615",-0.213,-0.823,0.709
"WP2854","Gene regulatory network modelling somitogenesis ","WP2854",0.475,0.841,0.712
"WP2643","Nanoparticle-mediated activation of receptor signaling","WP2643",-0.25,-0.82,0.72
"WP1422","Sphingolipid pathway","WP1422",-0.256,-0.815,0.721
"WP1471","Target Of Rapamycin (TOR) Signaling","WP1471",-0.24,-0.785,0.724
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis","WP2011",-0.292,-0.795,0.73
"WP4478","LTF danger signal response pathway","WP4478",-0.33,-0.779,0.732
"WP3655","Hypothetical Craniofacial Development Pathway","WP3655",0.412,0.812,0.734
"WP4629","Computational Model of Aerobic Glycolysis","WP4629",0.34,0.791,0.737
"WP4236","Disorders of the Krebs cycle","WP4236",0.32,0.768,0.741
"WP2447","Amyotrophic lateral sclerosis (ALS)","WP2447",-0.233,-0.81,0.746
"WP3286","Copper homeostasis","WP3286",-0.239,-0.838,0.748
"WP357","Fatty Acid Biosynthesis","WP357",-0.253,-0.798,0.75
"WP4582","Cancer immunotherapy by CTLA4 blockade","WP4582",-0.306,-0.761,0.751
"WP4147","PTF1A related regulatory pathway","WP4147",-0.371,-0.774,0.752
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)","WP2453",0.256,0.73,0.753
"WP2878","PPAR Alpha Pathway","WP2878",0.274,0.78,0.755
"WP3925","Amino Acid metabolism","WP3925",-0.216,-0.779,0.756
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling","WP4141",-0.27,-0.756,0.758
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)","WP111",-0.223,-0.653,0.759
"WP12","Osteoclast Signaling","WP12",0.333,0.759,0.759
"WP3529","Zinc homeostasis","WP3529",0.281,0.76,0.759
"WP4263","Pancreatic adenocarcinoma pathway","WP4263",0.203,0.833,0.764
"WP4329","miRNAs involvement in the immune response in sepsis","WP4329",-0.274,-0.745,0.772
"WP4742","Ketogenesis and Ketolysis","WP4742",-0.34,-0.791,0.779
"WP497","Urea cycle and metabolism of amino groups","WP497",-0.307,-0.79,0.787
"WP524","G13 Signaling Pathway","WP524",-0.2,-0.79,0.789
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits","WP3678",0.308,0.754,0.792
"WP4537","Hippo-Yap signaling pathway","WP4537",-0.277,-0.753,0.792
"WP4536","Genes related to primary cilium development (based on CRISPR)","WP4536",0.252,0.671,0.796
"WP138","Androgen receptor signaling pathway","WP138",-0.175,-0.716,0.798
"WP4549","Fragile X Syndrome ","WP4549",-0.191,-0.805,0.801
"WP2359","Parkin-Ubiquitin Proteasomal System pathway","WP2359",0.186,0.691,0.802
"WP2853","Endoderm Differentiation","WP2853",-0.223,-0.812,0.802
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation","WP368",-0.261,-0.708,0.809
"WP534","Glycolysis and Gluconeogenesis","WP534",-0.239,-0.734,0.813
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition","WP3859",-0.267,-0.707,0.818
"WP2507","Nanomaterial induced apoptosis","WP2507",0.271,0.728,0.824
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein","WP3872",-0.266,-0.715,0.828
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling","WP3612",-0.273,-0.666,0.829
"WP710","DNA Damage Response (only ATM dependent)","WP710",-0.201,-0.772,0.834
"WP2533","Glycerophospholipid Biosynthetic Pathway","WP2533",-0.238,-0.738,0.835
"WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway","WP3877",-0.312,-0.735,0.836
"WP623","Oxidative phosphorylation","WP623",0.218,0.554,0.839
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway","WP1433",-0.25,-0.627,0.841
"WP4674","Head and Neck Squamous Cell Carcinoma","WP4674",-0.191,-0.747,0.844
"WP106","Alanine and aspartate metabolism","WP106",0.355,0.663,0.845
"WP231","TNF alpha Signaling Pathway","WP231",-0.183,-0.729,0.851
"WP2828","Bladder Cancer","WP2828",0.242,0.736,0.852
"WP3874","Canonical and Non-Canonical TGF-B signaling","WP3874",-0.269,-0.61,0.858
"WP4558","Overview of interferons-mediated signaling pathway","WP4558",0.237,0.656,0.858
"WP4018","Pathways in clear cell renal cell carcinoma","WP4018",-0.203,-0.752,0.861
"WP4723","Omega-3/Omega-6 FA synthesis","WP4723",0.292,0.687,0.863
"WP2261","Signaling Pathways in Glioblastoma","WP2261",-0.204,-0.753,0.865
"WP4324","Mitochondrial complex I assembly model OXPHOS system","WP4324",0.179,0.485,0.865
"WP4159","GABA receptor Signaling","WP4159",0.267,0.649,0.874
"WP2249","Metastatic brain tumor","WP2249",-0.329,-0.684,0.875
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer","WP2864",-0.215,-0.669,0.88
"WP4562","Canonical NF-KB pathway","WP4562",-0.276,-0.646,0.883
"WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer","WP2868",0.306,0.616,0.898
"WP697","Estrogen metabolism","WP697",0.331,0.667,0.903
"WP4523","Classical pathway of steroidogenesis, including diseases","WP4523",-0.321,-0.655,0.904
"WP3926","ApoE and miR-146 in inflammation and atherosclerosis","WP3926",-0.279,-0.608,0.916
"WP400","p38 MAPK Signaling Pathway","WP400",0.179,0.675,0.916
"WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma","WP3593",-0.287,-0.653,0.917
"WP430","Statin Pathway","WP430",0.25,0.635,0.921
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway","WP3865",0.186,0.677,0.929
"WP100","Glutathione metabolism","WP100",-0.259,-0.591,0.933
"WP1531","Vitamin D Metabolism","WP1531",0.304,0.618,0.937
"WP268","Notch Signaling","WP268",0.172,0.642,0.938
"WP3645","NAD+ biosynthetic pathways","WP3645",-0.204,-0.657,0.939
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling","WP3614",0.208,0.608,0.944
"WP3937","Microglia Pathogen Phagocytosis Pathway","WP3937",0.225,0.495,0.946
"WP107","Translation Factors","WP107",0.122,0.544,0.947
"WP1772","Apoptosis Modulation and Signaling","WP1772",-0.192,-0.678,0.95
"WP691","Tamoxifen metabolism","WP691",0.302,0.549,0.954
"WP4655","Cytosolic DNA-sensing pathway","WP4655",-0.172,-0.52,0.964
"WP696","Benzo(a)pyrene metabolism","WP696",0.264,0.468,0.966
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling","WP1982",0.157,0.565,0.969
"WP80","Nucleotide GPCRs","WP80",-0.31,-0.584,0.969
"WP3871","Valproic acid pathway","WP3871",-0.228,-0.508,0.974
"WP4522","Metabolic pathway of LDL, HDL and TG, including diseases","WP4522",-0.261,-0.576,0.976
"WP3869","Cannabinoid receptor signaling","WP3869",0.197,0.611,0.982
"WP2513","Nanoparticle triggered regulated necrosis","WP2513",0.201,0.48,0.984
"WP2942","DDX1 as a regulatory component of the Drosha microprocessor","WP2942",-0.227,-0.518,0.984
"WP692","Sulfation Biotransformation Reaction","WP692",0.228,0.452,0.988
"WP325","Triacylglyceride Synthesis","WP325",0.176,0.46,0.998
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway","WP4577",0.0985,0.444,1
1 set_id name GENE.SET ES NES PVAL
2 WP289 Myometrial Relaxation and Contraction Pathways WP289 -0.593 -1.73 0
3 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR WP3414 -0.584 -1.75 0
4 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways WP706 -0.521 -1.74 0
5 WP98 Prostaglandin Synthesis and Regulation WP98 -0.667 -1.65 0
6 WP3981 miRNA regulation of prostate cancer signaling pathways WP3981 -0.528 -1.76 0.00191
7 WP536 Calcium Regulation in the Cardiac Cell WP536 -0.561 -1.7 0.00192
8 WP4321 Thermogenesis WP4321 -0.404 -1.61 0.00197
9 WP4589 Major receptors targeted by epinephrine and norepinephrine WP4589 -0.807 -1.62 0.00198
10 WP2858 Ectoderm Differentiation WP2858 -0.476 -1.6 0.00374
11 WP2516 ATM Signaling Pathway WP2516 0.653 1.8 0.00383
12 WP35 G Protein Signaling Pathways WP35 -0.563 -1.6 0.00387
13 WP4016 DNA IR-damage and cellular response via ATR WP4016 0.71 1.74 0.00588
14 WP170 Nuclear Receptors WP170 -0.669 -1.6 0.00592
15 WP4481 Resistin as a regulator of inflammation WP4481 -0.572 -1.56 0.00758
16 WP707 DNA Damage Response WP707 0.53 1.64 0.00772
17 WP1530 miRNA Regulation of DNA Damage Response WP1530 0.526 1.64 0.00781
18 WP531 DNA Mismatch Repair WP531 0.775 1.6 0.00783
19 WP383 Striated Muscle Contraction Pathway WP383 -0.737 -1.57 0.00803
20 WP304 Kit receptor signaling pathway WP304 -0.479 -1.56 0.00949
21 WP1971 Integrated Cancer Pathway WP1971 0.553 1.61 0.0116
22 WP2355 Corticotropin-releasing hormone signaling pathway WP2355 -0.492 -1.56 0.0116
23 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism WP4746 -0.393 -1.47 0.0133
24 WP3888 VEGFA-VEGFR2 Signaling Pathway WP3888 -0.366 -1.58 0.0134
25 WP554 ACE Inhibitor Pathway WP554 -0.805 -1.55 0.0134
26 WP4149 White fat cell differentiation WP4149 -0.615 -1.56 0.0135
27 WP2276 Glial Cell Differentiation WP2276 -0.861 -1.48 0.0143
28 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition WP4240 0.826 1.58 0.0157
29 WP2361 Gastric Cancer Network 1 WP2361 0.801 1.59 0.0158
30 WP4223 Ras Signaling WP4223 -0.428 -1.52 0.017
31 WP247 Small Ligand GPCRs WP247 -0.801 -1.44 0.0174
32 WP382 MAPK Signaling Pathway WP382 -0.414 -1.48 0.0174
33 WP1591 Heart Development WP1591 -0.614 -1.53 0.0192
34 WP206 Fatty Acid Omega Oxidation WP206 -0.862 -1.47 0.0195
35 WP466 DNA Replication WP466 0.807 1.58 0.0196
36 WP2197 Endothelin Pathways WP2197 -0.633 -1.52 0.0206
37 WP1528 Physiological and Pathological Hypertrophy of the Heart WP1528 -0.648 -1.51 0.0209
38 WP428 Wnt Signaling WP428 -0.453 -1.45 0.0209
39 WP4535 Envelope proteins and their potential roles in EDMD physiopathology WP4535 -0.459 -1.59 0.0209
40 WP3995 Prion disease pathway WP3995 -0.538 -1.6 0.0213
41 WP2338 miRNA Biogenesis WP2338 0.739 1.62 0.0214
42 WP3584 MECP2 and Associated Rett Syndrome WP3584 -0.416 -1.5 0.0218
43 WP236 Adipogenesis WP236 -0.503 -1.5 0.0249
44 WP179 Cell Cycle WP179 0.57 1.73 0.0251
45 WP4008 NO/cGMP/PKG mediated Neuroprotection WP4008 -0.544 -1.56 0.0252
46 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM WP3959 0.602 1.66 0.0257
47 WP186 Homologous recombination WP186 0.717 1.55 0.0282
48 WP465 Tryptophan metabolism WP465 -0.554 -1.57 0.0283
49 WP1992 Genes targeted by miRNAs in adipocytes WP1992 -0.742 -1.45 0.0291
50 WP3634 Insulin signalling in human adipocytes (normal condition) WP3634 -0.635 -1.56 0.0292
51 WP3635 Insulin signalling in human adipocytes (diabetic condition) WP3635 -0.635 -1.56 0.0292
52 WP1544 MicroRNAs in cardiomyocyte hypertrophy WP1544 -0.451 -1.47 0.033
53 WP2446 Retinoblastoma Gene in Cancer WP2446 0.705 1.65 0.0338
54 WP3853 ERK Pathway in Huntington's Disease WP3853 -0.564 -1.54 0.035
55 WP410 Exercise-induced Circadian Regulation WP410 -0.471 -1.48 0.035
56 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) WP4719 -0.625 -1.47 0.0378
57 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome WP4320 0.574 1.64 0.0383
58 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway WP2035 -0.448 -1.5 0.0384
59 WP167 Eicosanoid Synthesis WP167 -0.672 -1.5 0.0402
60 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS WP4304 -0.716 -1.46 0.0406
61 WP3875 ATR Signaling WP3875 0.771 1.48 0.0413
62 WP4760 PKC-gamma calcium signaling pathway in ataxia WP4760 -0.583 -1.39 0.0413
63 WP4222 Phosphodiesterases in neuronal function WP4222 -0.643 -1.49 0.0418
64 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy WP2118 -0.505 -1.46 0.042
65 WP45 G1 to S cell cycle control WP45 0.596 1.65 0.0421
66 WP2034 Leptin signaling pathway WP2034 -0.384 -1.48 0.0427
67 WP3996 Ethanol effects on histone modifications WP3996 -0.456 -1.49 0.0427
68 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation WP1991 -0.786 -1.38 0.043
69 WP2848 Differentiation Pathway WP2848 -0.632 -1.48 0.043
70 WP2363 Gastric Cancer Network 2 WP2363 0.639 1.54 0.0437
71 WP3893 Development and heterogeneity of the ILC family WP3893 -0.714 -1.49 0.0437
72 WP4753 Nucleotide Excision Repair WP4753 0.554 1.62 0.0455
73 WP4752 Base Excision Repair WP4752 0.679 1.53 0.0466
74 WP2895 Differentiation of white and brown adipocyte WP2895 -0.639 -1.46 0.0469
75 WP2406 Cardiac Progenitor Differentiation WP2406 -0.62 -1.45 0.047
76 WP58 Monoamine GPCRs WP58 -0.824 -1.38 0.0474
77 WP2029 Cell Differentiation - Index WP2029 -0.785 -1.35 0.0524
78 WP4519 Cerebral Organic Acidurias, including diseases WP4519 -0.657 -1.48 0.0542
79 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma WP4336 -0.422 -1.43 0.0552
80 WP4172 PI3K-Akt Signaling Pathway WP4172 -0.398 -1.38 0.0565
81 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia WP3658 -0.488 -1.45 0.0566
82 WP4022 Pyrimidine metabolism WP4022 0.528 1.56 0.057
83 WP4155 Endometrial cancer WP4155 -0.388 -1.4 0.0595
84 WP2064 Neural Crest Differentiation WP2064 -0.441 -1.39 0.0596
85 WP2525 Trans-sulfuration and one carbon metabolism WP2525 0.581 1.52 0.0603
86 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression WP3879 0.45 1.48 0.0611
87 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) WP2814 -0.667 -1.44 0.0655
88 WP404 Nucleotide Metabolism WP404 0.653 1.54 0.0663
89 WP2795 Cardiac Hypertrophic Response WP2795 -0.451 -1.44 0.0667
90 WP4545 Oxysterols derived from cholesterol WP4545 -0.676 -1.41 0.0686
91 WP481 Insulin Signaling WP481 -0.343 -1.37 0.0687
92 WP4756 Renin Angiotensin Aldosterone System (RAAS) WP4756 -0.498 -1.39 0.069
93 WP241 One Carbon Metabolism WP241 0.479 1.45 0.0696
94 WP4595 Urea cycle and associated pathways WP4595 0.565 1.44 0.07
95 WP306 Focal Adhesion WP306 -0.449 -1.43 0.0709
96 WP3931 ESC Pluripotency Pathways WP3931 -0.411 -1.38 0.0725
97 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway WP3932 -0.397 -1.39 0.0725
98 WP4191 Caloric restriction and aging WP4191 -0.712 -1.43 0.0727
99 WP4540 Pathways Regulating Hippo Signaling WP4540 -0.449 -1.38 0.0775
100 WP1545 miRNAs involved in DNA damage response WP1545 0.485 1.4 0.0778
101 WP49 IL-2 Signaling Pathway WP49 -0.477 -1.42 0.0799
102 WP4225 Pyrimidine metabolism and related diseases WP4225 0.59 1.41 0.0805
103 WP4290 Metabolic reprogramming in colon cancer WP4290 0.554 1.57 0.0817
104 WP673 ErbB Signaling Pathway WP673 -0.361 -1.36 0.0821
105 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling WP734 -0.53 -1.42 0.0821
106 WP4754 IL-18 signaling pathway WP4754 -0.375 -1.38 0.0832
107 WP34 Ovarian Infertility Genes WP34 -0.513 -1.41 0.0833
108 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma WP4337 -0.611 -1.4 0.0835
109 WP3594 Circadian rhythm related genes WP3594 -0.341 -1.31 0.0842
110 WP4521 Glycosylation and related congenital defects WP4521 0.576 1.45 0.0853
111 WP474 Endochondral Ossification WP474 -0.506 -1.37 0.0857
112 WP3599 Transcription factor regulation in adipogenesis WP3599 -0.561 -1.39 0.0863
113 WP3947 Serotonin and anxiety WP3947 -0.731 -1.37 0.0867
114 WP3298 Melatonin metabolism and effects WP3298 -0.527 -1.36 0.0872
115 WP3934 Leptin and adiponectin WP3934 -0.574 -1.42 0.0874
116 WP51 Regulation of Actin Cytoskeleton WP51 -0.367 -1.34 0.088
117 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation WP3876 -0.665 -1.4 0.0884
118 WP2374 Oncostatin M Signaling Pathway WP2374 -0.447 -1.42 0.0889
119 WP1424 Globo Sphingolipid Metabolism WP1424 -0.6 -1.37 0.0928
120 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk WP3943 -0.755 -1.4 0.0932
121 WP545 Complement Activation WP545 -0.746 -1.39 0.0932
122 WP185 Integrin-mediated Cell Adhesion WP185 -0.377 -1.32 0.0934
123 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness WP3301 -0.489 -1.32 0.0937
124 WP3878 ATM Signaling Network in Development and Disease WP3878 0.458 1.46 0.0946
125 WP3413 NOTCH1 regulation of human endothelial cell calcification WP3413 -0.601 -1.39 0.095
126 WP2059 Alzheimers Disease WP2059 -0.298 -1.23 0.0986
127 WP286 IL-3 Signaling Pathway WP286 -0.457 -1.41 0.0994
128 WP704 Methylation Pathways WP704 -0.668 -1.36 0.1
129 WP716 Vitamin A and Carotenoid Metabolism WP716 -0.535 -1.38 0.1
130 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) WP2813 -0.612 -1.37 0.101
131 WP2636 Common Pathways Underlying Drug Addiction WP2636 -0.497 -1.44 0.102
132 WP1541 Energy Metabolism WP1541 -0.475 -1.41 0.103
133 WP2806 Human Complement System WP2806 -0.583 -1.43 0.104
134 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement WP4560 -0.634 -1.4 0.104
135 WP1423 Ganglio Sphingolipid Metabolism WP1423 -0.666 -1.34 0.106
136 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling WP3679 -0.754 -1.35 0.108
137 WP363 Wnt Signaling Pathway (Netpath) WP363 -0.42 -1.37 0.109
138 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation WP4767 -0.419 -1.31 0.113
139 WP3935 Leptin Insulin Overlap WP3935 -0.603 -1.34 0.114
140 WP4698 Vitamin D-sensitive calcium signaling in depression WP4698 -0.447 -1.27 0.114
141 WP4507 Molybdenum cofactor (Moco) biosynthesis WP4507 -0.615 -1.33 0.115
142 WP3640 Imatinib and Chronic Myeloid Leukemia WP3640 -0.537 -1.36 0.117
143 WP3929 Chemokine signaling pathway WP3929 -0.442 -1.38 0.117
144 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer WP4258 -0.363 -1.26 0.117
145 WP4666 Hepatitis B infection WP4666 -0.322 -1.31 0.119
146 WP3591 Sleep regulation WP3591 -0.6 -1.39 0.12
147 WP3595 mir-124 predicted interactions with cell cycle and differentiation WP3595 0.591 1.35 0.121
148 WP28 Selenium Metabolism and Selenoproteins WP28 -0.387 -1.32 0.122
149 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma WP4553 0.494 1.33 0.122
150 WP3287 Overview of nanoparticle effects WP3287 -0.534 -1.3 0.123
151 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway WP2380 -0.341 -1.3 0.127
152 WP2267 Synaptic Vesicle Pathway WP2267 -0.488 -1.37 0.128
153 WP2855 Dopaminergic Neurogenesis WP2855 -0.712 -1.36 0.128
154 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling WP732 -0.421 -1.32 0.131
155 WP4249 Hedgehog Signaling Pathway WP4249 -0.561 -1.36 0.132
156 WP4747 Netrin-UNC5B signaling Pathway WP4747 -0.426 -1.33 0.132
157 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ WP3849 -0.477 -1.3 0.134
158 WP2023 Cell Differentiation - Index expanded WP2023 -0.561 -1.29 0.138
159 WP3299 let-7 inhibition of ES cell reprogramming WP3299 -0.737 -1.34 0.139
160 WP4482 Vitamin D in inflammatory diseases WP4482 -0.477 -1.33 0.14
161 WP1601 Fluoropyrimidine Activity WP1601 0.506 1.29 0.144
162 WP2849 Hematopoietic Stem Cell Differentiation WP2849 -0.533 -1.33 0.146
163 WP3672 LncRNA-mediated mechanisms of therapeutic resistance WP3672 -0.67 -1.32 0.146
164 WP4659 Gastrin Signaling Pathway WP4659 -0.344 -1.3 0.147
165 WP2879 Farnesoid X Receptor Pathway WP2879 -0.73 -1.31 0.148
166 WP2881 Estrogen Receptor Pathway WP2881 -0.614 -1.32 0.149
167 WP2882 Nuclear Receptors Meta-Pathway WP2882 -0.385 -1.26 0.15
168 WP364 IL-6 signaling pathway WP364 -0.394 -1.34 0.15
169 WP411 mRNA Processing WP411 0.338 1.46 0.152
170 WP2037 Prolactin Signaling Pathway WP2037 -0.313 -1.25 0.153
171 WP2431 Spinal Cord Injury WP2431 -0.426 -1.26 0.155
172 WP395 IL-4 Signaling Pathway WP395 -0.39 -1.28 0.16
173 WP3585 Cytosine methylation WP3585 0.581 1.35 0.161
174 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity WP3969 0.53 1.3 0.161
175 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses WP1589 -0.568 -1.28 0.168
176 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy WP1559 -0.569 -1.32 0.171
177 WP405 Eukaryotic Transcription Initiation WP405 0.392 1.34 0.176
178 WP4352 Ciliary landscape WP4352 0.26 1.25 0.177
179 WP558 Complement and Coagulation Cascades WP558 -0.583 -1.32 0.18
180 WP23 B Cell Receptor Signaling Pathway WP23 -0.393 -1.3 0.181
181 WP530 Cytokines and Inflammatory Response WP530 -0.655 -1.29 0.181
182 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) WP2840 -0.447 -1.24 0.182
183 WP3407 FTO Obesity Variant Mechanism WP3407 -0.613 -1.26 0.182
184 WP3930 EDA Signalling in Hair Follicle Development WP3930 -0.617 -1.28 0.182
185 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS WP2572 -0.408 -1.27 0.186
186 WP2456 HIF1A and PPARG regulation of glycolysis WP2456 0.689 1.31 0.188
187 WP3892 Development of pulmonary dendritic cells and macrophage subsets WP3892 -0.708 -1.26 0.191
188 WP4216 Chromosomal and microsatellite instability in colorectal cancer WP4216 -0.345 -1.24 0.194
189 WP262 EBV LMP1 signaling WP262 -0.449 -1.26 0.197
190 WP2332 Interleukin-11 Signaling Pathway WP2332 -0.331 -1.21 0.198
191 WP2916 Interactome of polycomb repressive complex 2 (PRC2) WP2916 0.405 1.27 0.198
192 WP4571 Urea cycle and related diseases WP4571 0.701 1.24 0.198
193 WP3656 Interleukin-1 Induced Activation of NF-kappa-B WP3656 0.567 1.28 0.199
194 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms WP4534 -0.341 -1.18 0.199
195 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment WP4480 -0.549 -1.26 0.208
196 WP2290 RalA downstream regulated genes WP2290 0.514 1.23 0.21
197 WP4211 Transcriptional cascade regulating adipogenesis WP4211 -0.559 -1.25 0.211
198 WP183 Proteasome Degradation WP183 0.445 1.33 0.212
199 WP24 Peptide GPCRs WP24 -0.631 -1.27 0.215
200 WP3927 BMP Signaling Pathway in Eyelid Development WP3927 -0.493 -1.23 0.216
201 WP4312 Rett syndrome causing genes WP4312 -0.37 -1.21 0.218
202 WP4792 Purine metabolism WP4792 0.618 1.28 0.22
203 WP2112 IL17 signaling pathway WP2112 -0.357 -1.21 0.221
204 WP1539 Angiogenesis WP1539 -0.526 -1.27 0.224
205 WP2113 Type III interferon signaling WP2113 0.583 1.25 0.224
206 WP322 Osteoblast Signaling WP322 -0.706 -1.26 0.229
207 WP4538 Regulatory circuits of the STAT3 signaling pathway WP4538 -0.406 -1.22 0.23
208 WP3963 Mevalonate pathway WP3963 0.715 1.24 0.233
209 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway WP2036 -0.386 -1.24 0.234
210 WP4724 Omega-9 FA synthesis WP4724 0.565 1.26 0.237
211 WP4541 Hippo-Merlin Signaling Dysregulation WP4541 -0.376 -1.18 0.241
212 WP438 Non-homologous end joining WP438 0.473 1.25 0.242
213 WP4396 Nonalcoholic fatty liver disease WP4396 -0.284 -1.21 0.242
214 WP1602 Nicotine Activity on Dopaminergic Neurons WP1602 -0.511 -1.19 0.244
215 WP127 IL-5 Signaling Pathway WP127 -0.372 -1.2 0.248
216 WP1533 Vitamin B12 Metabolism WP1533 -0.473 -1.23 0.25
217 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway WP69 -0.433 -1.23 0.251
218 WP3933 Kennedy pathway from Sphingolipids WP3933 0.506 1.22 0.252
219 WP3944 Serotonin and anxiety-related events WP3944 -0.635 -1.2 0.252
220 WP1984 Integrated Breast Cancer Pathway WP1984 0.27 1.13 0.254
221 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) WP4718 0.445 1.24 0.254
222 WP4685 Melanoma WP4685 -0.295 -1.15 0.255
223 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway WP2018 -0.366 -1.19 0.256
224 WP2333 Trans-sulfuration pathway WP2333 0.537 1.22 0.256
225 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway WP3670 -0.428 -1.18 0.256
226 WP4331 Neovascularisation processes WP4331 -0.438 -1.2 0.256
227 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway WP2203 -0.423 -1.21 0.257
228 WP4483 Relationship between inflammation, COX-2 and EGFR WP4483 -0.398 -1.16 0.257
229 WP15 Selenium Micronutrient Network WP15 -0.393 -1.17 0.259
230 WP3965 Lipid Metabolism Pathway WP3965 -0.414 -1.19 0.259
231 WP134 Pentose Phosphate Metabolism WP134 0.659 1.23 0.26
232 WP408 Oxidative Stress WP408 -0.45 -1.19 0.263
233 WP143 Fatty Acid Beta Oxidation WP143 -0.377 -1.19 0.264
234 WP455 GPCRs, Class A Rhodopsin-like WP455 -0.481 -1.19 0.264
235 WP2870 Extracellular vesicle-mediated signaling in recipient cells WP2870 -0.366 -1.13 0.265
236 WP2485 NAD Biosynthesis II (from tryptophan) WP2485 -0.587 -1.18 0.266
237 WP3958 GPR40 Pathway WP3958 -0.499 -1.17 0.266
238 WP4298 Viral Acute Myocarditis WP4298 -0.357 -1.16 0.266
239 WP712 Estrogen signaling pathway WP712 -0.436 -1.2 0.266
240 WP3527 Preimplantation Embryo WP3527 -0.413 -1.15 0.267
241 WP4259 Disorders of Folate Metabolism and Transport WP4259 0.47 1.16 0.273
242 WP4153 Degradation pathway of sphingolipids, including diseases WP4153 0.505 1.18 0.274
243 WP4241 Type 2 papillary renal cell carcinoma WP4241 -0.375 -1.16 0.274
244 WP2637 Structural Pathway of Interleukin 1 (IL-1) WP2637 -0.341 -1.16 0.277
245 WP197 Cholesterol Biosynthesis Pathway WP197 0.661 1.24 0.278
246 WP313 Signaling of Hepatocyte Growth Factor Receptor WP313 -0.379 -1.19 0.278
247 WP561 Heme Biosynthesis WP561 0.528 1.19 0.281
248 WP2272 Pathogenic Escherichia coli infection WP2272 -0.319 -1.14 0.282
249 WP3580 Methionine De Novo and Salvage Pathway WP3580 -0.415 -1.15 0.282
250 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 WP4269 -0.519 -1.17 0.282
251 WP4493 Cells and Molecules involved in local acute inflammatory response WP4493 -0.65 -1.22 0.282
252 WP4586 Metabolism of alpha-linolenic acid WP4586 0.576 1.15 0.285
253 WP3596 miR-517 relationship with ARCN1 and USP1 WP3596 -0.599 -1.19 0.286
254 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex WP3657 0.324 1.11 0.287
255 WP2805 exRNA mechanism of action and biogenesis WP2805 0.571 1.2 0.29
256 WP2007 Iron metabolism in placenta WP2007 0.518 1.17 0.295
257 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells WP4301 -0.346 -1.12 0.297
258 WP47 Hedgehog Signaling Pathway Netpath WP47 -0.591 -1.19 0.302
259 WP4462 Platelet-mediated interactions with vascular and circulating cells WP4462 -0.601 -1.18 0.303
260 WP4136 Fibrin Complement Receptor 3 Signaling Pathway WP4136 -0.439 -1.15 0.309
261 WP516 Hypertrophy Model WP516 -0.482 -1.13 0.309
262 WP4300 Extracellular vesicles in the crosstalk of cardiac cells WP4300 -0.426 -1.1 0.314
263 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection WP3863 -0.393 -1.15 0.318
264 WP205 IL-7 Signaling Pathway WP205 -0.402 -1.17 0.32
265 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging WP4186 -0.599 -1.18 0.321
266 WP4217 Ebola Virus Pathway on Host WP4217 -0.343 -1.13 0.321
267 WP117 GPCRs, Other WP117 -0.459 -1.12 0.322
268 WP422 MAPK Cascade WP422 -0.299 -1.09 0.323
269 WP4496 Signal transduction through IL1R WP4496 -0.404 -1.13 0.325
270 WP4585 Cancer immunotherapy by PD-1 blockade WP4585 -0.556 -1.18 0.329
271 WP176 Folate Metabolism WP176 -0.349 -1.08 0.33
272 WP4584 Biomarkers for pyrimidine metabolism disorders WP4584 0.455 1.12 0.33
273 WP2874 Liver X Receptor Pathway WP2874 0.643 1.16 0.333
274 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway WP3915 -0.259 -1.08 0.334
275 WP399 Wnt Signaling Pathway and Pluripotency WP399 -0.304 -1.06 0.335
276 WP4389 Bile Acids synthesis and enterohepatic circulation WP4389 -0.571 -1.15 0.336
277 WP4255 Non-small cell lung cancer WP4255 -0.256 -1.05 0.338
278 WP3851 TLR4 Signaling and Tolerance WP3851 -0.371 -1.11 0.339
279 WP53 ID signaling pathway WP53 0.455 1.09 0.339
280 WP4288 MTHFR deficiency WP4288 0.371 1.09 0.342
281 WP3972 PDGFR-beta pathway WP3972 -0.395 -1.13 0.346
282 WP727 Monoamine Transport WP727 -0.423 -1.09 0.35
283 WP3624 Lung fibrosis WP3624 -0.434 -1.08 0.357
284 WP4657 22q11.2 Deletion Syndrome WP4657 -0.344 -1.08 0.358
285 WP3644 NAD+ metabolism WP3644 -0.394 -1.08 0.359
286 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment WP4559 -0.497 -1.14 0.36
287 WP560 TGF-beta Receptor Signaling WP560 -0.378 -1.1 0.36
288 WP3998 Prader-Willi and Angelman Syndrome WP3998 -0.341 -1.05 0.361
289 WP500 Glycogen Synthesis and Degradation WP500 -0.335 -1.08 0.361
290 WP4583 Biomarkers for urea cycle disorders WP4583 -0.531 -1.09 0.366
291 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase WP678 -0.587 -1.12 0.366
292 WP4148 Splicing factor NOVA regulated synaptic proteins WP4148 -0.356 -1.06 0.367
293 WP4539 Synaptic signaling pathways associated with autism spectrum disorder WP4539 -0.36 -1.09 0.37
294 WP2328 Allograft Rejection WP2328 -0.491 -1.13 0.374
295 WP4286 Genotoxicity pathway WP4286 -0.329 -1.04 0.377
296 WP4210 Tryptophan catabolism leading to NAD+ production WP4210 -0.434 -1.04 0.379
297 WP4262 Breast cancer pathway WP4262 -0.275 -1.05 0.381
298 WP1403 AMP-activated Protein Kinase (AMPK) Signaling WP1403 -0.299 -1.06 0.383
299 WP2369 Histone Modifications WP2369 0.324 1.04 0.384
300 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling WP3850 -0.341 -1.05 0.385
301 WP3940 One carbon metabolism and related pathways WP3940 -0.339 -1.03 0.385
302 WP4494 Selective expression of chemokine receptors during T-cell polarization WP4494 -0.557 -1.13 0.389
303 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation WP314 0.286 1.06 0.392
304 WP136 Phase I biotransformations, non P450 WP136 -0.557 -1.1 0.393
305 WP4565 Neural Crest Cell Migration in Cancer WP4565 -0.339 -1.05 0.393
306 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders WP4292 -0.476 -1.05 0.398
307 WP4479 Supression of HMGB1 mediated inflammation by THBD WP4479 -0.422 -1.05 0.402
308 WP1584 Type II diabetes mellitus WP1584 -0.362 -1.03 0.406
309 WP2371 Parkinsons Disease Pathway WP2371 0.325 1.05 0.407
310 WP2877 Vitamin D Receptor Pathway WP2877 -0.348 -1.04 0.407
311 WP3300 Dual hijack model of Vif in HIV infection WP3300 0.506 1.07 0.407
312 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus WP4142 -0.397 -1.03 0.411
313 WP3941 Oxidative Damage WP3941 -0.375 -1.06 0.413
314 WP437 EGF/EGFR Signaling Pathway WP437 -0.239 -1.02 0.415
315 WP4239 Epithelial to mesenchymal transition in colorectal cancer WP4239 -0.29 -1.03 0.417
316 WP4224 Purine metabolism and related disorders WP4224 0.377 1.05 0.419
317 WP4197 The human immune response to tuberculosis WP4197 0.435 1.08 0.421
318 WP391 Mitochondrial Gene Expression WP391 -0.372 -1.06 0.422
319 WP4722 Glycerolipids and Glycerophospholipids WP4722 0.368 1.03 0.422
320 WP4658 Small cell lung cancer WP4658 -0.276 -1.01 0.423
321 WP3303 RAC1/PAK1/p38/MMP2 Pathway WP3303 0.257 1.02 0.426
322 WP3613 Photodynamic therapy-induced unfolded protein response WP3613 0.34 1 0.433
323 WP366 TGF-beta Signaling Pathway WP366 -0.28 -1.02 0.434
324 WP1455 Serotonin Transporter Activity WP1455 -0.465 -1.02 0.439
325 WP2509 Nanoparticle triggered autophagic cell death WP2509 -0.322 -0.999 0.439
326 WP4705 Pathways of nucleic acid metabolism and innate immune sensing WP4705 0.426 1.03 0.441
327 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway WP4206 -0.313 -1.02 0.445
328 WP2857 Mesodermal Commitment Pathway WP2857 -0.306 -1 0.447
329 WP698 Glucuronidation WP698 -0.409 -1.01 0.447
330 WP272 Blood Clotting Cascade WP272 -0.435 -0.996 0.448
331 WP195 IL-1 signaling pathway WP195 -0.278 -1.01 0.45
332 WP2324 AGE/RAGE pathway WP2324 -0.275 -1.01 0.451
333 WP4673 Genes involved in male infertility WP4673 -0.254 -0.991 0.461
334 WP129 Matrix Metalloproteinases WP129 0.414 1 0.463
335 WP61 Notch Signaling Pathway Netpath WP61 -0.264 -0.992 0.465
336 WP2436 Dopamine metabolism WP2436 -0.44 -0.996 0.466
337 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways WP3680 -0.301 -1.01 0.466
338 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity WP299 -0.475 -1.04 0.469
339 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) WP2817 -0.386 -0.992 0.472
340 WP2884 NRF2 pathway WP2884 -0.303 -0.962 0.473
341 WP1449 Regulation of toll-like receptor signaling pathway WP1449 -0.277 -0.979 0.477
342 WP2865 IL1 and megakaryocytes in obesity WP2865 -0.45 -1.01 0.48
343 WP3630 NAD metabolism, sirtuins and aging WP3630 -0.418 -0.976 0.484
344 WP585 Interferon type I signaling pathways WP585 -0.262 -0.964 0.485
345 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions WP4542 -0.37 -1.01 0.488
346 WP1434 Osteopontin Signaling WP1434 0.388 0.984 0.492
347 WP4564 Neural Crest Cell Migration during Development WP4564 -0.322 -0.997 0.494
348 WP78 TCA Cycle (aka Krebs or citric acid cycle) WP78 -0.371 -0.991 0.5
349 WP2876 Pregnane X Receptor pathway WP2876 -0.414 -0.967 0.502
350 WP4726 Sphingolipid Metabolism (integrated pathway) WP4726 -0.334 -0.965 0.502
351 WP3676 BDNF-TrkB Signaling WP3676 -0.304 -0.973 0.504
352 WP26 Signal Transduction of S1P Receptor WP26 -0.311 -0.971 0.508
353 WP4150 Wnt Signaling in Kidney Disease WP4150 -0.336 -0.951 0.509
354 WP4504 Cysteine and methionine catabolism WP4504 -0.38 -0.935 0.513
355 WP3651 Pathways Affected in Adenoid Cystic Carcinoma WP3651 0.262 0.969 0.516
356 WP229 Irinotecan Pathway WP229 -0.521 -0.964 0.523
357 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 WP4341 -0.285 -0.944 0.523
358 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease WP3668 -0.379 -0.944 0.526
359 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds WP3664 -0.399 -0.973 0.527
360 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases WP4518 0.542 0.979 0.527
361 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) WP4721 -0.378 -0.93 0.533
362 WP501 GPCRs, Class C Metabotropic glutamate, pheromone WP501 -0.575 -0.97 0.533
363 WP4725 Sphingolipid Metabolism (general overview) WP4725 -0.335 -0.937 0.534
364 WP3945 TYROBP Causal Network WP3945 -0.435 -0.974 0.535
365 WP3845 Canonical and Non-canonical Notch signaling WP3845 0.325 0.923 0.536
366 WP4146 Macrophage markers WP4146 -0.564 -0.992 0.536
367 WP4297 Thiamine metabolic pathways WP4297 -0.382 -0.913 0.536
368 WP2583 T-Cell Receptor and Co-stimulatory Signaling WP2583 -0.337 -0.914 0.539
369 WP3967 miR-509-3p alteration of YAP1/ECM axis WP3967 -0.467 -0.965 0.542
370 WP3971 Role of Osx and miRNAs in tooth development WP3971 -0.442 -0.939 0.543
371 WP4566 Translation inhibitors in chronically activated PDGFRA cells WP4566 -0.244 -0.935 0.545
372 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation WP1425 -0.436 -0.943 0.55
373 WP453 Inflammatory Response Pathway WP453 -0.418 -0.94 0.551
374 WP4561 Cell migration and invasion through p75NTR WP4561 -0.322 -0.906 0.552
375 WP22 IL-9 Signaling Pathway WP22 -0.308 -0.905 0.554
376 WP3982 miRNA regulation of p53 pathway in prostate cancer WP3982 0.364 0.941 0.558
377 WP4656 Joubert Syndrome WP4656 0.288 0.9 0.563
378 WP288 NLR Proteins WP288 0.405 0.94 0.567
379 WP311 Synthesis and Degradation of Ketone Bodies WP311 -0.466 -0.927 0.569
380 WP2875 Constitutive Androstane Receptor Pathway WP2875 -0.356 -0.905 0.573
381 WP1946 Cori Cycle WP1946 -0.359 -0.886 0.58
382 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway WP2032 -0.242 -0.93 0.58
383 WP4204 Tumor suppressor activity of SMARCB1 WP4204 0.295 0.893 0.589
384 WP1742 TP53 Network WP1742 -0.333 -0.904 0.59
385 WP4758 Nephrotic syndrome WP4758 -0.27 -0.922 0.594
386 WP2911 miRNA targets in ECM and membrane receptors WP2911 -0.47 -0.937 0.596
387 WP2873 Aryl Hydrocarbon Receptor Pathway WP2873 -0.307 -0.892 0.599
388 WP4313 Ferroptosis WP4313 0.289 0.879 0.606
389 WP4495 IL-10 Anti-inflammatory Signaling Pathway WP4495 -0.362 -0.879 0.617
390 WP3942 PPAR signaling pathway WP3942 -0.292 -0.906 0.618
391 WP3617 Photodynamic therapy-induced NF-kB survival signaling WP3617 -0.361 -0.873 0.619
392 WP3611 Photodynamic therapy-induced AP-1 survival signaling. WP3611 -0.267 -0.895 0.622
393 WP384 Apoptosis Modulation by HSP70 WP384 0.318 0.853 0.626
394 WP4205 MET in type 1 papillary renal cell carcinoma WP4205 -0.218 -0.869 0.627
395 WP4357 NRF2-ARE regulation WP4357 0.316 0.862 0.631
396 WP581 EPO Receptor Signaling WP581 -0.272 -0.869 0.634
397 WP477 Cytoplasmic Ribosomal Proteins WP477 -0.308 -0.853 0.64
398 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities WP3844 -0.261 -0.869 0.641
399 WP702 Metapathway biotransformation Phase I and II WP702 -0.293 -0.878 0.643
400 WP254 Apoptosis WP254 0.276 0.863 0.645
401 WP4271 Vitamin B12 Disorders WP4271 0.357 0.859 0.651
402 WP3 Phytochemical activity on NRF2 transcriptional activation WP3 0.378 0.847 0.654
403 WP4532 Intraflagellar transport proteins binding to dynein WP4532 -0.285 -0.813 0.654
404 WP3858 Toll-like Receptor Signaling related to MyD88 WP3858 -0.309 -0.84 0.655
405 WP43 Oxidation by Cytochrome P450 WP43 -0.341 -0.849 0.655
406 WP75 Toll-like Receptor Signaling Pathway WP75 -0.248 -0.846 0.66
407 WP2526 PDGF Pathway WP2526 -0.25 -0.854 0.661
408 WP2586 Aryl Hydrocarbon Receptor Netpath WP2586 -0.267 -0.852 0.662
409 WP619 Type II interferon signaling (IFNG) WP619 0.354 0.788 0.664
410 WP2038 Regulation of Microtubule Cytoskeleton WP2038 0.266 0.817 0.68
411 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) WP2815 0.385 0.834 0.689
412 WP244 Alpha 6 Beta 4 signaling pathway WP244 -0.25 -0.793 0.692
413 WP3646 Hepatitis C and Hepatocellular Carcinoma WP3646 0.255 0.824 0.696
414 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer WP2291 -0.393 -0.794 0.704
415 WP4533 Transcription co-factors SKI and SKIL protein partners WP4533 -0.308 -0.829 0.705
416 WP615 Senescence and Autophagy in Cancer WP615 -0.213 -0.823 0.709
417 WP2854 Gene regulatory network modelling somitogenesis WP2854 0.475 0.841 0.712
418 WP2643 Nanoparticle-mediated activation of receptor signaling WP2643 -0.25 -0.82 0.72
419 WP1422 Sphingolipid pathway WP1422 -0.256 -0.815 0.721
420 WP1471 Target Of Rapamycin (TOR) Signaling WP1471 -0.24 -0.785 0.724
421 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis WP2011 -0.292 -0.795 0.73
422 WP4478 LTF danger signal response pathway WP4478 -0.33 -0.779 0.732
423 WP3655 Hypothetical Craniofacial Development Pathway WP3655 0.412 0.812 0.734
424 WP4629 Computational Model of Aerobic Glycolysis WP4629 0.34 0.791 0.737
425 WP4236 Disorders of the Krebs cycle WP4236 0.32 0.768 0.741
426 WP2447 Amyotrophic lateral sclerosis (ALS) WP2447 -0.233 -0.81 0.746
427 WP3286 Copper homeostasis WP3286 -0.239 -0.838 0.748
428 WP357 Fatty Acid Biosynthesis WP357 -0.253 -0.798 0.75
429 WP4582 Cancer immunotherapy by CTLA4 blockade WP4582 -0.306 -0.761 0.751
430 WP4147 PTF1A related regulatory pathway WP4147 -0.371 -0.774 0.752
431 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) WP2453 0.256 0.73 0.753
432 WP2878 PPAR Alpha Pathway WP2878 0.274 0.78 0.755
433 WP3925 Amino Acid metabolism WP3925 -0.216 -0.779 0.756
434 WP4141 PI3K/AKT/mTOR - VitD3 Signalling WP4141 -0.27 -0.756 0.758
435 WP111 Electron Transport Chain (OXPHOS system in mitochondria) WP111 -0.223 -0.653 0.759
436 WP12 Osteoclast Signaling WP12 0.333 0.759 0.759
437 WP3529 Zinc homeostasis WP3529 0.281 0.76 0.759
438 WP4263 Pancreatic adenocarcinoma pathway WP4263 0.203 0.833 0.764
439 WP4329 miRNAs involvement in the immune response in sepsis WP4329 -0.274 -0.745 0.772
440 WP4742 Ketogenesis and Ketolysis WP4742 -0.34 -0.791 0.779
441 WP497 Urea cycle and metabolism of amino groups WP497 -0.307 -0.79 0.787
442 WP524 G13 Signaling Pathway WP524 -0.2 -0.79 0.789
443 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits WP3678 0.308 0.754 0.792
444 WP4537 Hippo-Yap signaling pathway WP4537 -0.277 -0.753 0.792
445 WP4536 Genes related to primary cilium development (based on CRISPR) WP4536 0.252 0.671 0.796
446 WP138 Androgen receptor signaling pathway WP138 -0.175 -0.716 0.798
447 WP4549 Fragile X Syndrome WP4549 -0.191 -0.805 0.801
448 WP2359 Parkin-Ubiquitin Proteasomal System pathway WP2359 0.186 0.691 0.802
449 WP2853 Endoderm Differentiation WP2853 -0.223 -0.812 0.802
450 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation WP368 -0.261 -0.708 0.809
451 WP534 Glycolysis and Gluconeogenesis WP534 -0.239 -0.734 0.813
452 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition WP3859 -0.267 -0.707 0.818
453 WP2507 Nanomaterial induced apoptosis WP2507 0.271 0.728 0.824
454 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein WP3872 -0.266 -0.715 0.828
455 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling WP3612 -0.273 -0.666 0.829
456 WP710 DNA Damage Response (only ATM dependent) WP710 -0.201 -0.772 0.834
457 WP2533 Glycerophospholipid Biosynthetic Pathway WP2533 -0.238 -0.738 0.835
458 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway WP3877 -0.312 -0.735 0.836
459 WP623 Oxidative phosphorylation WP623 0.218 0.554 0.839
460 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway WP1433 -0.25 -0.627 0.841
461 WP4674 Head and Neck Squamous Cell Carcinoma WP4674 -0.191 -0.747 0.844
462 WP106 Alanine and aspartate metabolism WP106 0.355 0.663 0.845
463 WP231 TNF alpha Signaling Pathway WP231 -0.183 -0.729 0.851
464 WP2828 Bladder Cancer WP2828 0.242 0.736 0.852
465 WP3874 Canonical and Non-Canonical TGF-B signaling WP3874 -0.269 -0.61 0.858
466 WP4558 Overview of interferons-mediated signaling pathway WP4558 0.237 0.656 0.858
467 WP4018 Pathways in clear cell renal cell carcinoma WP4018 -0.203 -0.752 0.861
468 WP4723 Omega-3/Omega-6 FA synthesis WP4723 0.292 0.687 0.863
469 WP2261 Signaling Pathways in Glioblastoma WP2261 -0.204 -0.753 0.865
470 WP4324 Mitochondrial complex I assembly model OXPHOS system WP4324 0.179 0.485 0.865
471 WP4159 GABA receptor Signaling WP4159 0.267 0.649 0.874
472 WP2249 Metastatic brain tumor WP2249 -0.329 -0.684 0.875
473 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer WP2864 -0.215 -0.669 0.88
474 WP4562 Canonical NF-KB pathway WP4562 -0.276 -0.646 0.883
475 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer WP2868 0.306 0.616 0.898
476 WP697 Estrogen metabolism WP697 0.331 0.667 0.903
477 WP4523 Classical pathway of steroidogenesis, including diseases WP4523 -0.321 -0.655 0.904
478 WP3926 ApoE and miR-146 in inflammation and atherosclerosis WP3926 -0.279 -0.608 0.916
479 WP400 p38 MAPK Signaling Pathway WP400 0.179 0.675 0.916
480 WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma WP3593 -0.287 -0.653 0.917
481 WP430 Statin Pathway WP430 0.25 0.635 0.921
482 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway WP3865 0.186 0.677 0.929
483 WP100 Glutathione metabolism WP100 -0.259 -0.591 0.933
484 WP1531 Vitamin D Metabolism WP1531 0.304 0.618 0.937
485 WP268 Notch Signaling WP268 0.172 0.642 0.938
486 WP3645 NAD+ biosynthetic pathways WP3645 -0.204 -0.657 0.939
487 WP3614 Photodynamic therapy-induced HIF-1 survival signaling WP3614 0.208 0.608 0.944
488 WP3937 Microglia Pathogen Phagocytosis Pathway WP3937 0.225 0.495 0.946
489 WP107 Translation Factors WP107 0.122 0.544 0.947
490 WP1772 Apoptosis Modulation and Signaling WP1772 -0.192 -0.678 0.95
491 WP691 Tamoxifen metabolism WP691 0.302 0.549 0.954
492 WP4655 Cytosolic DNA-sensing pathway WP4655 -0.172 -0.52 0.964
493 WP696 Benzo(a)pyrene metabolism WP696 0.264 0.468 0.966
494 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling WP1982 0.157 0.565 0.969
495 WP80 Nucleotide GPCRs WP80 -0.31 -0.584 0.969
496 WP3871 Valproic acid pathway WP3871 -0.228 -0.508 0.974
497 WP4522 Metabolic pathway of LDL, HDL and TG, including diseases WP4522 -0.261 -0.576 0.976
498 WP3869 Cannabinoid receptor signaling WP3869 0.197 0.611 0.982
499 WP2513 Nanoparticle triggered regulated necrosis WP2513 0.201 0.48 0.984
500 WP2942 DDX1 as a regulatory component of the Drosha microprocessor WP2942 -0.227 -0.518 0.984
501 WP692 Sulfation Biotransformation Reaction WP692 0.228 0.452 0.988
502 WP325 Triacylglyceride Synthesis WP325 0.176 0.46 0.998
503 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway WP4577 0.0985 0.444 1

496
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"ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count","odds_ratio"
"WP2446","Retinoblastoma Gene in Cancer","47/1022","86/4839",6.08288534347113e-12,3.01102824501821e-09,2.81733636960768e-09,"25/54443/890/891/9133/898/9134/993/8318/8317/983/1017/1019/81620/1111/1786/1869/1870/2189/24137/4173/4175/4176/2956/4609/4998/5111/10733/5426/5427/5557/5591/5928/5947/5983/5984/5985/6119/6241/6502/10592/3925/7027/7153/7272/7298/7465",47,4.66971729125575
"WP466","DNA Replication","26/1022","41/4839",4.88122298123165e-09,1.20810268785483e-06,1.13038847986417e-06,"8318/990/8317/1017/81620/10926/55388/4171/4173/4174/4175/4176/4998/23594/5111/23649/5424/5426/5427/5557/5558/5982/5983/5984/5985/6119",26,6.61659973226238
"WP2361","Gastric Cancer Network 1","16/1022","22/4839",2.8778815405389e-07,4.20813701870437e-05,3.93743814615614e-05,"86/6790/1063/144455/1894/56992/9585/286826/4173/4605/57122/8607/64094/7153/22974/11065",16,10.1020543406229
"WP179","Cell Cycle","48/1022","115/4839",3.40051476258939e-07,4.20813701870437e-05,3.93743814615614e-05,"25/699/9184/890/891/9133/894/898/9134/991/993/995/8318/990/8317/983/1017/1019/1028/1111/11200/10926/1869/1870/9700/4616/2932/3066/10459/4171/4173/4174/4175/4176/4609/4998/23594/5111/9088/5347/5591/9232/5933/6502/7027/7043/7272/7465",48,2.75828250942413
"WP45","G1 to S cell cycle control","30/1022","61/4839",9.28021377109086e-07,9.18741163337995e-05,8.59640854585259e-05,"891/894/898/9134/993/8318/983/1017/1019/1028/90993/1869/1870/4171/4173/4174/4175/4176/4609/4998/23594/5111/23649/5426/5427/5557/5558/6119/7027/7465",30,3.69341831425598
"WP289","Myometrial Relaxation and Contraction Pathways","46/1022","120/4839",9.77018041145599e-06,0.000806039883945119,0.000754189365094849,"58/59/70/108/196883/111/115/408/467/489/800/817/1264/2353/2791/55970/54331/2788/2869/3488/3489/3569/3708/1902/23764/4846/5142/5144/11142/5331/5336/5577/5579/5590/10267/10266/10268/5996/8786/10287/5997/8490/8787/6262/6263/6546",46,2.38394439521489
"WP4016","DNA IR-damage and cellular response via ATR","31/1022","75/4839",5.22036834352934e-05,0.00369154618578146,0.00345407830248558,"672/675/83990/995/8318/983/1017/1111/11200/1196/63967/1869/9156/2175/2177/55215/2237/2305/4171/4436/79728/5111/5347/5591/5888/5883/55159/80010/55775/11073/7507",31,2.68239152371342
"WP383","Striated Muscle Contraction Pathway","13/1022","23/4839",0.000209501159191158,0.0129628842249529,0.0121290144794881,"58/59/70/1674/1756/10398/8736/7111/7139/7168/7169/7170/7431",13,4.90495540138751
"WP536","Calcium Regulation in the Cardiac Cell","38/1022","107/4839",0.000369441897512897,0.0203193043632093,0.0190122146088508,"108/196883/111/115/154/309/408/482/489/775/811/817/845/2701/57165/2775/2781/2791/55970/54331/2788/2869/3708/11142/5331/5350/5577/5579/5590/5996/8786/10287/5997/8490/8787/6262/6263/6546",38,2.09767880287499
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation","7/1022","9/4839",0.000442625689689891,0.0219099716396496,0.0205005582593213,"817/894/9314/4208/4209/93649/6722",7,13.1551724137931
"WP531","DNA Mismatch Repair","11/1022","21/4839",0.00152210454302198,0.0629714363335005,0.0589206421833923,"9156/3978/4436/2956/5111/5424/5982/5983/5984/5985/6119",11,4.14213649851632
"WP2406","Cardiac Progenitor Differentiation","14/1022","30/4839",0.00152658027475153,0.0629714363335005,0.0589206421833923,"70/22943/2247/2932/3479/3624/3815/4208/4684/5156/4920/64321/6910/7139",14,3.29947916666667
"WP1530","miRNA Regulation of DNA Damage Response","24/1022","64/4839",0.00186690102319929,0.0710858466525883,0.0665130728913107,"25/637/672/891/9133/894/898/9134/993/995/983/1017/1019/1020/1111/11200/1869/2177/4616/4176/4609/5591/5888/5883",24,2.27074148296593
"WP35","G Protein Signaling Pathways","27/1022","76/4839",0.00250847820080499,0.0790149987243626,0.0739321625491112,"108/196883/111/115/9590/11214/9472/9465/9630/2774/2775/2781/2791/55970/2788/3708/4893/5136/5142/5144/27115/5331/5533/5577/5579/5590/6237",27,2.08667828940621
"WP707","DNA Damage Response","23/1022","62/4839",0.00271330802302758,0.0790149987243626,0.0739321625491112,"25/637/672/891/9133/894/898/9134/993/995/983/1017/1019/1020/1111/11200/1869/2177/4616/4609/5591/5888/5883",23,2.2302815636149
"WP1602","Nicotine Activity on Dopaminergic Neurons","7/1022","11/4839",0.00271364642083669,0.0790149987243626,0.0739321625491112,"108/1020/1138/54331/3777/84152/6571",7,6.57413793103448
"WP2023","Cell Differentiation - Index expanded","7/1022","11/4839",0.00271364642083669,0.0790149987243626,0.0739321625491112,"2146/10014/3398/9314/4208/4209/6722",7,6.57413793103448
"WP2848","Differentiation Pathway","12/1022","26/4839",0.0036947121263992,0.0968690978699419,0.0906377523929281,"22943/2247/3082/3479/3569/3570/3624/3815/4907/7043/7472/7482",12,3.22743988684583
"WP558","Complement and Coagulation Cascades","16/1022","39/4839",0.00371820779702807,0.0968690978699419,0.0906377523929281,"623/715/716/718/730/1675/3075/1191/2159/2161/2157/5648/5627/710/7035/7450",16,2.62356297000605
"WP2516","ATM Signaling Pathway","15/1022","37/4839",0.00561025279060555,0.138853756567487,0.129921643571918,"25/637/672/835/891/898/993/995/983/1017/1111/11200/2177/5888/5883",15,2.5695134061569
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition","8/1022","15/4839",0.00595545166757851,0.140378503592922,0.131348307455366,"699/701/9184/991/1062/9700/4085/9232",8,4.29416737109045
"WP4222","Phosphodiesterases in neuronal function","13/1022","31/4839",0.00694925428195734,0.149785380106981,0.140150063257994,"108/196883/111/115/2906/5136/5138/5140/5142/5144/8654/27115/84152",13,2.71924898138971
"WP236","Adipogenesis","33/1022","104/4839",0.00695972473224355,0.149785380106981,0.140150063257994,"1052/1675/55847/1869/1879/1959/2308/2487/4616/3479/3569/3572/28999/1316/3977/4154/4208/4209/4692/7025/2908/5465/10891/5740/5914/5933/6095/6319/6517/9021/6773/6777/25937",33,1.76046369216309
"WP2806","Human Complement System","22/1022","63/4839",0.00765136578770975,0.151658530005302,0.141902718133616,"715/716/718/730/811/966/22918/1675/3075/5199/1634/2159/2161/2162/3690/5648/5627/5806/6401/6403/710/6696",22,2.02614634146341
"WP3996","Ethanol effects on histone modifications","12/1022","28/4839",0.00765952171743951,0.151658530005302,0.141902718133616,"125/126/191/217/3066/9759/10014/10013/8850/4524/6573/7298",12,2.82252475247525
"WP247","Small Ligand GPCRs","6/1022","10/4839",0.00837134097206408,0.153474584487841,0.14360195039798,"1902/5733/5734/5737/1901/9294",6,5.62942913385827
"WP4545","Oxysterols derived from cholesterol","6/1022","10/4839",0.00837134097206408,0.153474584487841,0.14360195039798,"9023/1593/1717/2053/2099/1880",6,5.62942913385827
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma","7/1022","13/4839",0.00947004961583731,0.167416948565695,0.156647437254452,"3590/3569/3570/3572/3717/6659/6935",7,4.38045977011494
"WP2363","Gastric Cancer Network 2","12/1022","29/4839",0.0106076900909422,0.181062296379876,0.169415014156609,"29028/27101/63922/79075/55215/84823/4609/5983/5984/7153/11065/29089",12,2.65579499126383
"WP1971","Integrated Cancer Pathway","16/1022","43/4839",0.0111649064981956,0.184220957220227,0.172370486287932,"596/641/672/993/983/1017/1019/1111/11200/1869/4312/4436/2956/4609/5347/5451",16,2.23253074147706
"WP474","Endochondral Ossification","19/1022","54/4839",0.0116567995879756,0.18613276761445,0.17415931472697,"9510/9507/11096/1028/5167/2247/2260/2487/2690/9759/3479/4208/4256/4322/5745/6696/6777/7067/7078",19,2.04694487964677
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways","31/1022","100/4839",0.012513191903912,0.193563437263639,0.181111988082937,"34/627/1390/1958/2305/23171/7184/3569/3570/3757/4150/4204/4208/4602/2908/4915/5354/10891/133522/5577/6095/6262/6330/291/6640/6869/6929/11076/7259/6844/7434",31,1.69917664780123
"WP4149","White fat cell differentiation","12/1022","30/4839",0.0143601520308822,0.214413838417165,0.20062113536109,"1052/1879/1959/2308/28999/10365/9314/2908/5914/6095/6777/23090",12,2.50759075907591
"WP4589","Major receptors targeted by epinephrine and norepinephrine","6/1022","11/4839",0.0151605744335369,0.214413838417165,0.20062113536109,"108/196883/111/115/150/154",6,4.50236220472441
"WP554","ACE Inhibitor Pathway","6/1022","11/4839",0.0151605744335369,0.214413838417165,0.20062113536109,"185/623/624/1511/4846/4306",6,4.50236220472441
"WP2431","Spinal Cord Injury","28/1022","90/4839",0.0162686915442285,0.221975388746869,0.207696270172509,"358/627/7832/6347/983/1017/1019/1464/2920/1869/1958/2353/3569/4321/4609/4804/3164/9423/5320/56963/388/65078/6403/9353/6586/6869/7431/7538",28,1.70604270786006
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM","18/1022","52/4839",0.0165920997649174,0.221975388746869,0.207696270172509,"25/86/637/641/672/675/995/1020/1111/11200/1869/9156/2177/5111/5591/5888/5883/10413",18,1.99478556362784
"WP2029","Cell Differentiation - Index","4/1022","6/4839",0.0205766471129607,0.261165136433732,0.244365039937995,"10014/4208/4209/6722",4,7.4950884086444
"WP3944","Serotonin and anxiety-related events","4/1022","6/4839",0.0205766471129607,0.261165136433732,0.244365039937995,"2353/2906/84812/5579",4,7.4950884086444
"WP3893","Development and heterogeneity of the ILC family","8/1022","18/4839",0.0221682040659433,0.274331525316048,0.256684468131975,"374/3398/90865/3569/6095/9760/85480/7704",8,3.00355029585799
"WP516","Hypertrophy Model","7/1022","15/4839",0.023921397351209,0.281930754496392,0.26379485800832,"467/1978/1839/3727/8013/9948/6935",7,3.28362068965517
"WP545","Complement Activation","7/1022","15/4839",0.023921397351209,0.281930754496392,0.26379485800832,"715/716/718/730/1675/5199/5648",7,3.28362068965517
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)","6/1022","12/4839",0.0249881820525124,0.283655270848162,0.265408440559683,"374/2099/8061/4609/5241/7431",6,3.7509842519685
"WP428","Wnt Signaling","28/1022","93/4839",0.0252138018531699,0.283655270848162,0.265408440559683,"817/894/1457/23500/22943/8061/2535/8324/2932/4609/4772/4776/85407/51701/5331/5332/5532/5533/166336/5579/4919/4920/5176/6422/64321/81839/7472/7482",28,1.62600216684724
"WP4172","PI3K-Akt Signaling Pathway","66/1022","252/4839",0.0279094709530498,0.306261336676163,0.286560315018632,"10000/284/596/627/672/894/898/9134/1017/1019/1286/1288/1291/1292/90993/9586/1440/1944/1945/1975/1978/2256/2258/2247/2252/2260/2690/2791/55970/54331/2788/2932/3082/7184/3479/3563/3569/3570/3678/3679/8516/3680/3690/3717/3815/3908/3913/10319/1902/4602/4609/4804/4846/4893/4915/80310/5156/5516/5521/5525/5563/5649/6696/7010/7148/7450",66,1.34771899041706
"WP170","Nuclear Receptors","11/1022","29/4839",0.028460649468896,0.306261336676163,0.286560315018632,"2099/7025/2908/3164/4929/5241/5465/5914/4919/6095/7067",11,2.29635124738982
"WP3297","EV release from cardiac cells and their functional effects","3/1022","4/4839",0.0316543966692141,0.333381411728957,0.31193582383996,"6387/10365/4602",3,11.234543670265
"WP2858","Ectoderm Differentiation","32/1022","112/4839",0.0363507203093282,0.369978106127767,0.34617834491487,"79658/55843/23229/91653/10486/6347/5010/1756/2534/8322/2627/10013/3853/9079/4204/4609/4772/51701/51422/56963/114822/4920/6386/6622/8835/114815/10253/6781/6929/7226/8848/7704",32,1.50989898989899
"WP4752","Base Excision Repair","11/1022","30/4839",0.0366240953540618,0.369978106127767,0.34617834491487,"2237/3978/4595/10038/5111/11284/5424/5426/5427/23583/7374",11,2.17491800718413
"WP3591","Sleep regulation","6/1022","13/4839",0.0382894384268054,0.379065440425373,0.354681113848302,"191/1471/2353/3569/8863/5730",6,3.21428571428571
"WP1992","Genes targeted by miRNAs in adipocytes","5/1022","10/4839",0.0406085173589397,0.38656184793606,0.361695296314442,"2078/9464/9759/3479/6722",5,3.74827925270403
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)","5/1022","10/4839",0.0406085173589397,0.38656184793606,0.361695296314442,"1116/1869/3572/4609/9021",5,3.74827925270403
"WP1984","Integrated Breast Cancer Pathway","39/1022","143/4839",0.0451540264348633,0.421721567646365,0.394593279669113,"25/6790/596/637/641/672/675/993/1017/1019/1111/11200/55526/1869/26284/2099/27145/8061/2308/4312/4436/2956/4609/79902/4953/5347/1263/5888/8438/5906/6237/23411/4092/6597/7035/7048/27005/7465/7517",39,1.41645473041709
"WP34","Ovarian Infertility Genes","7/1022","17/4839",0.0488930677721469,0.440037609949322,0.411731097028606,"894/1019/1958/2701/5241/6609/7784",7,2.62551724137931
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells","7/1022","17/4839",0.0488930677721469,0.440037609949322,0.411731097028606,"332/975/3479/3569/10611/8470/6696",7,2.62551724137931
"WP2849","Hematopoietic Stem Cell Differentiation","14/1022","43/4839",0.0536575816417183,0.467920123508186,0.43781999860415,"863/947/1440/2313/2353/2354/3569/3663/3690/3757/4602/3071/399/7148",14,1.81417624521073
"WP1601","Fluoropyrimidine Activity","10/1022","28/4839",0.0538817111918517,0.467920123508186,0.43781999860415,"1066/8836/4524/5471/6241/23583/7083/7298/7371/7517",10,2.08552920509442
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation","5/1022","11/4839",0.0618151364634419,0.524734603786845,0.490979746233305,"1634/22943/2308/6422/4093",5,3.12274664044576
"WP241","One Carbon Metabolism","9/1022","25/4839",0.062831257423353,0.524734603786845,0.490979746233305,"191/1786/1788/1789/2618/25902/4524/6472/7298",9,2.11062438302073
"WP2895","Differentiation of white and brown adipocyte ","7/1022","18/4839",0.0658997992215493,0.524734603786845,0.490979746233305,"253738/27129/10891/133522/63976/4093/23090",7,2.38620689655172
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy","17/1022","56/4839",0.0661533109186531,0.524734603786845,0.490979746233305,"775/781/783/785/1674/1756/3678/3679/8516/3680/3690/3908/6262/6442/6443/6444/6546",17,1.63862737594081
"WP206","Fatty Acid Omega Oxidation","3/1022","5/4839",0.0667844041183257,0.524734603786845,0.490979746233305,"125/126/217",3,5.61579980372915
"WP3299","let-7 inhibition of ES cell reprogramming","3/1022","5/4839",0.0667844041183257,0.524734603786845,0.490979746233305,"1958/9314/4609",3,5.61579980372915
"WP98","Prostaglandin Synthesis and Regulation","12/1022","37/4839",0.0728698633344591,0.559196388737501,0.523224691216376,"309/1909/1910/4286/10891/133522/5730/5733/5734/5737/5740/5742",12,1.80213861386139
"WP4698","Vitamin D-sensitive calcium signaling in depression","8/1022","22/4839",0.0734298288241164,0.559196388737501,0.523224691216376,"493/596/775/1593/2906/3708/23028/6546",8,2.14313891236968
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma","20/1022","69/4839",0.0752279353205046,0.564209514903784,0.527915335582488,"894/1457/22943/2146/8061/2535/8324/2932/9314/4609/85407/51701/4919/4920/5176/6422/64321/83595/7472/7482",20,1.53488940486374
"WP3998","Prader-Willi and Angelman Syndrome","10/1022","30/4839",0.0825797783657116,0.610104332701899,0.570857855159672,"627/894/990/1019/1869/9638/4487/4692/5108/5590",10,1.87598814229249
"WP4224","Purine metabolism and related disorders","7/1022","19/4839",0.0860390711246063,0.623135020434443,0.583050311517608,"316/1716/2618/3251/3704/10606/5471",7,2.1867816091954
"WP3624","Lung fibrosis","13/1022","42/4839",0.087955807542379,0.623135020434443,0.583050311517608,"6347/1440/2920/2006/2247/2252/3082/3479/3569/4204/5806/4092/6696",13,1.68292266156317
"WP4760","PKC-gamma calcium signaling pathway in ataxia","5/1022","12/4839",0.0881201038998203,0.623135020434443,0.583050311517608,"9630/3708/5331/5332/6263",5,2.67593763168984
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway","60/1022","243/4839",0.0951492832930012,0.663364721549797,0.620692137122617,"10000/284/1301/1286/1288/1292/90993/9586/1440/1944/1945/1975/1978/2256/2258/2247/2252/2260/2308/2690/2791/55970/54331/2788/2932/3082/64344/7184/3479/3563/3570/3678/3679/8516/3680/3690/3717/3815/3908/3913/10319/1902/4804/4846/4893/80310/5156/5210/10891/5516/5521/5525/5563/5649/6515/6517/6696/7010/7148/7450",60,1.23853992706452
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling","4/1022","9/4839",0.100966138374052,0.685679647373976,0.641571599882083,"3708/6262/6263/7220",4,2.99567779960707
"WP497","Urea cycle and metabolism of amino groups","6/1022","16/4839",0.101120432845051,0.685679647373976,0.641571599882083,"5832/1152/2593/162417/4953/5831",6,2.24822834645669
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer","21/1022","76/4839",0.106066145727212,0.70949651533743,0.663856388619817,"467/894/1457/22943/2146/8061/2535/8324/2932/4609/85407/51701/4919/4920/8607/5176/6422/64321/6929/7472/7482",21,1.43496503496503
"WP2338","miRNA Biogenesis","3/1022","6/4839",0.112992161123691,0.735935786266143,0.688594887734403,"5901/6895/57510",3,3.74288518155054
"WP4571","Urea cycle and related diseases","3/1022","6/4839",0.112992161123691,0.735935786266143,0.688594887734403,"162417/10165/10166",3,3.74288518155054
"WP1495","Glycine Metabolism","2/1022","3/4839",0.114915958441986,0.738745447127052,0.691223810177358,"4524/6472",2,7.48235294117647
"WP2355","Corticotropin-releasing hormone signaling pathway","20/1022","73/4839",0.120714965545451,0.766075742884595,0.716796016734124,"408/596/8912/2353/2354/8061/2775/2781/2932/3726/3727/4846/3164/4929/5336/5563/5579/10411/9095/6925",20,1.41754227394268
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement","6/1022","17/4839",0.12960808652118,0.812101301620054,0.759860867012917,"3690/3708/4026/8076/4638/7414",6,2.04330708661417
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia","7/1022","21/4839",0.135477853961833,0.83826922138884,0.784345470305348,"22943/2932/4609/5914/862/6929/7704",7,1.87339901477833
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)","8/1022","25/4839",0.138618514440201,0.84711314380123,0.792620485428051,"857/2099/3717/4609/2908/5241/7170/7528",8,1.76354565494837
"WP2855","Dopaminergic Neurogenesis","4/1022","10/4839",0.141204552384128,0.852393334513942,0.797561014749887,"1028/4487/4929/6571",4,2.49574328749181
"WP2877","Vitamin D Receptor Pathway","30/1022","118/4839",0.148165697304679,0.883638797178506,0.826796535371702,"5243/11096/154/623/768/898/4345/1017/78989/1474/2308/50486/29923/3400/3488/3663/3726/9365/9314/4609/5734/6304/7869/6422/6517/6546/6696/79689/7078/7168",30,1.28150201612903
"WP1545","miRNAs involved in DNA damage response","5/1022","14/4839",0.1547702251525,0.912038826791517,0.853369662494987,"25/898/993/1869/4609",5,2.08019228668196
"WP1541","Energy Metabolism","12/1022","42/4839",0.15854563148268,0.912159802926657,0.853482856539562,"2308/2932/4208/4209/5465/10891/133522/5532/5533/5563/51422/23411",12,1.49980198019802
"WP2038","Regulation of Microtubule Cytoskeleton","12/1022","42/4839",0.15854563148268,0.912159802926657,0.853482856539562,"25/9212/983/1073/1808/2048/2932/11004/3984/4131/3925/11076",12,1.49980198019802
"WP117","GPCRs, Other","7/1022","22/4839",0.1644335990261,0.912159802926657,0.853482856539562,"154/1951/1909/1880/59352/5737/1901",7,1.74804597701149
"WP2879","Farnesoid X Receptor Pathway","3/1022","7/4839",0.167689983972375,0.912159802926657,0.853482856539562,"5244/2289/10891",3,2.80642787046124
"WP322","Osteoblast Signaling","3/1022","7/4839",0.167689983972375,0.912159802926657,0.853482856539562,"3690/5156/5745",3,2.80642787046124
"WP3407","FTO Obesity Variant Mechanism","3/1022","7/4839",0.167689983972375,0.912159802926657,0.853482856539562,"84159/10891/63976",3,2.80642787046124
"WP3947","Serotonin and anxiety","3/1022","7/4839",0.167689983972375,0.912159802926657,0.853482856539562,"2353/84812/5579",3,2.80642787046124
"WP3594","Circadian rhythm related genes","34/1022","138/4839",0.177587188667422,0.920698826812516,0.861472586491243,"191/1019/1390/1408/1471/1958/1960/2146/2932/3066/3398/3400/3569/3727/3778/7071/687/56339/4804/4841/5187/8864/8863/5465/10891/5563/5591/5730/6095/23411/8914/7153/7298/9099",34,1.22860868888197
"WP4321","Thermogenesis","23/1022","90/4839",0.180110321104423,0.920698826812516,0.861472586491243,"86/108/196883/111/115/353500/656/90993/9586/2260/23028/11343/4881/4893/10891/63976/5563/51422/5592/6196/6597/6598/6602",23,1.28860203487069
"WP4259","Disorders of Folate Metabolism and Transport","4/1022","11/4839",0.186569932910234,0.920698826812516,0.861472586491243,"2618/4524/6472/7298",4,2.13864720740949
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)","15/1022","56/4839",0.187328788615833,0.920698826812516,0.861472586491243,"6868/4345/947/22943/1959/2353/2354/3479/3488/4487/4772/2908/6422/6929/6925",15,1.37186039189091
"WP2197","Endothelin Pathways","7/1022","23/4839",0.195858426981202,0.920698826812516,0.861472586491243,"790/1264/1909/1910/4638/4846/10267",7,1.63836206896552
"WP3599","Transcription factor regulation in adipogenesis","6/1022","19/4839",0.196272918961637,0.920698826812516,0.861472586491243,"1052/2308/3569/2908/10891/6517",6,1.72804360993337
"WP4288","MTHFR deficiency","6/1022","19/4839",0.196272918961637,0.920698826812516,0.861472586491243,"501/1786/1788/1789/2906/4524",6,1.72804360993337
"WP1995","Effects of Nitric Oxide","2/1022","4/4839",0.198177520214758,0.920698826812516,0.861472586491243,"316/4846",2,3.74019607843137
"WP2542","Sulindac Metabolic Pathway","2/1022","4/4839",0.198177520214758,0.920698826812516,0.861472586491243,"4482/253827",2,3.74019607843137
"WP334","GPCRs, Class B Secretin-like","2/1022","4/4839",0.198177520214758,0.920698826812516,0.861472586491243,"5745/7434",2,3.74019607843137
"WP4720","Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway","2/1022","4/4839",0.198177520214758,0.920698826812516,0.861472586491243,"2053/5465",2,3.74019607843137
"WP176","Folate Metabolism","12/1022","44/4839",0.20300016766834,0.920698826812516,0.861472586491243,"191/6347/80308/2350/2618/2878/3569/4524/12/6472/6573/6649",12,1.40532178217822
"WP410","Exercise-induced Circadian Regulation","12/1022","44/4839",0.20300016766834,0.920698826812516,0.861472586491243,"11335/7122/1408/50486/2674/687/5187/8864/5516/5813/11030/10381",12,1.40532178217822
"WP1438","Influenza A virus infection","1/1022","1/4839",0.211200661293655,0.920698826812516,0.861472586491243,"596",1,Inf
"WP1600","Nicotine Metabolism","1/1022","1/4839",0.211200661293655,0.920698826812516,0.861472586491243,"316",1,Inf
"WP1603","Nicotine Activity on Chromaffin Cells","1/1022","1/4839",0.211200661293655,0.920698826812516,0.861472586491243,"775",1,Inf
"WP4400","FABP4 in ovarian cancer","1/1022","1/4839",0.211200661293655,0.920698826812516,0.861472586491243,"2167",1,Inf
"WP2525","Trans-sulfuration and one carbon metabolism","8/1022","28/4839",0.224525950160984,0.920698826812516,0.861472586491243,"191/1786/1788/1789/25902/4524/6472/7298",8,1.49783037475345
"WP1455","Serotonin Transporter Activity","3/1022","8/4839",0.228117947120316,0.920698826812516,0.861472586491243,"3690/5516/7041",3,2.24455348380765
"WP3875","ATR Signaling","3/1022","8/4839",0.228117947120316,0.920698826812516,0.861472586491243,"1111/5883/11073",3,2.24455348380765
"WP4191","Caloric restriction and aging","3/1022","8/4839",0.228117947120316,0.920698826812516,0.861472586491243,"3479/10891/23411",3,2.24455348380765
"WP4583","Biomarkers for urea cycle disorders","3/1022","8/4839",0.228117947120316,0.920698826812516,0.861472586491243,"2159/2593/162417",3,2.24455348380765
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS","15/1022","58/4839",0.228867396275626,0.920698826812516,0.861472586491243,"375790/1028/1286/22943/2534/3611/3690/3913/4288/55742/5111/11346/7094/7414/7431",15,1.30736010715688
"WP4657","22q11.2 Deletion Syndrome","15/1022","58/4839",0.228867396275626,0.920698826812516,0.861472586491243,"59/70/8318/7122/2260/9464/5308/5902/65078/6576/6517/6722/27037/7450/7625",15,1.30736010715688
"WP1528","Physiological and Pathological Hypertrophy of the Heart","7/1022","24/4839",0.229413888363834,0.920698826812516,0.861472586491243,"817/2353/3572/3977/4776/5532/5579",7,1.54158215010142
"WP3640","Imatinib and Chronic Myeloid Leukemia","6/1022","20/4839",0.233557704720861,0.920698826812516,0.861472586491243,"5243/25/3815/4609/5156/6502",6,1.60419010123735
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein","6/1022","20/4839",0.233557704720861,0.920698826812516,0.861472586491243,"596/83596/599/637/2932/4609",6,1.60419010123735
"WP4538","Regulatory circuits of the STAT3 signaling pathway","17/1022","67/4839",0.235097418060392,0.920698826812516,0.861472586491243,"185/2690/3590/58985/3563/3570/3572/3717/3977/225689/5156/5579/5789/80854/9021/3925/7297",17,1.27440796019901
"WP4658","Small cell lung cancer","22/1022","89/4839",0.235584492112176,0.920698826812516,0.861472586491243,"10000/596/637/330/898/9134/1017/1019/1028/1163/1164/1286/1288/1869/1870/4616/3908/3913/10319/4609/7185/7186",22,1.23134328358209
"WP186","Homologous recombination","4/1022","12/4839",0.235794847415441,0.920698826812516,0.861472586491243,"675/5424/5888/25788",4,1.87082514734774
"WP272","Blood Clotting Cascade","4/1022","12/4839",0.235794847415441,0.920698826812516,0.861472586491243,"2159/2161/2157/7450",4,1.87082514734774
"WP4584","Biomarkers for pyrimidine metabolism disorders","4/1022","12/4839",0.235794847415441,0.920698826812516,0.861472586491243,"1152/80324/6241/7298",4,1.87082514734774
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis","5/1022","16/4839",0.236219699000383,0.920698826812516,0.861472586491243,"2194/5465/10891/6319/23411",5,1.70108161258604
"WP2878","PPAR Alpha Pathway","5/1022","16/4839",0.236219699000383,0.920698826812516,0.861472586491243,"34/983/1019/4609/5465",5,1.70108161258604
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS","5/1022","16/4839",0.236219699000383,0.920698826812516,0.861472586491243,"2920/2247/3479/5354/6663",5,1.70108161258604
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling","5/1022","16/4839",0.236219699000383,0.920698826812516,0.861472586491243,"1958/2908/5906/9252/6722",5,1.70108161258604
"WP2064","Neural Crest Differentiation","16/1022","64/4839",0.264602321898724,0.999930074063124,0.935607086842689,"2247/2260/2932/3066/9759/10014/10013/4286/4359/4487/4602/4609/5376/388/6663/6925",16,1.24884029158383
"WP2374","Oncostatin M Signaling Pathway","16/1022","64/4839",0.264602321898724,0.999930074063124,0.935607086842689,"6347/1017/1958/2353/3572/3717/3726/3727/3977/4312/4322/5579/9021/6777/7078/7297",16,1.24884029158383
"WP3584","MECP2 and Associated Rett Syndrome","13/1022","51/4839",0.268668191587185,0.999930074063124,0.935607086842689,"627/1052/1465/1869/2146/2247/2289/2571/2593/114787/3479/4204/4208",13,1.28128423139116
"WP24","Peptide GPCRs","6/1022","21/4839",0.272789645024472,0.999930074063124,0.935607086842689,"185/623/624/1909/1910/6869",6,1.49685039370079
"WP382","MAPK Signaling Pathway","45/1022","195/4839",0.272925856991294,0.999930074063124,0.935607086842689,"10000/408/627/775/8912/781/783/785/1843/1850/2256/2258/2247/2252/2260/2316/2318/2353/55970/3306/3727/120892/9020/1326/23542/4208/4609/4772/51701/3164/4893/4915/8605/5532/5533/5881/5906/10235/9252/6237/6722/3925/7043/7048/7186",45,1.12599795291709
"WP727","Monoamine Transport","5/1022","17/4839",0.28064120420005,0.999930074063124,0.935607086842689,"995/114907/3690/5516/7041",5,1.55891510980007
"WP136","Phase I biotransformations, non P450","2/1022","5/4839",0.285772930945712,0.999930074063124,0.935607086842689,"1066/2098",2,2.49281045751634
"WP2276","Glial Cell Differentiation","2/1022","5/4839",0.285772930945712,0.999930074063124,0.935607086842689,"5354/11076",2,2.49281045751634
"WP2874","Liver X Receptor Pathway","2/1022","5/4839",0.285772930945712,0.999930074063124,0.935607086842689,"2194/6319",2,2.49281045751634
"WP58","Monoamine GPCRs","2/1022","5/4839",0.285772930945712,0.999930074063124,0.935607086842689,"150/154",2,2.49281045751634
"WP3958","GPR40 Pathway","4/1022","13/4839",0.287586215235435,0.999930074063124,0.935607086842689,"5310/5331/5336/5334",4,1.66251910063305
"WP4211","Transcriptional cascade regulating adipogenesis","4/1022","13/4839",0.287586215235435,0.999930074063124,0.935607086842689,"1052/1959/28999/10365",4,1.66251910063305
"WP4493","Cells and Molecules involved in local acute inflammatory response ","4/1022","13/4839",0.287586215235435,0.999930074063124,0.935607086842689,"718/730/3569/6403",4,1.66251910063305
"WP53","ID signaling pathway","4/1022","13/4839",0.287586215235435,0.999930074063124,0.935607086842689,"898/1017/3398/5933",4,1.66251910063305
"WP4753","Nucleotide Excision Repair","11/1022","43/4839",0.288668808814214,0.999930074063124,0.935607086842689,"3978/5111/5424/5426/5427/5982/5983/5984/5985/6119/7507",11,1.28693743818002
"WP1591","Heart Development","8/1022","30/4839",0.290225800257854,0.999930074063124,0.935607086842689,"2627/9464/4208/4772/4776/5308/6722/6910",8,1.36094674556213
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder","10/1022","39/4839",0.299745088293227,0.999930074063124,0.935607086842689,"10000/627/775/1978/2906/2932/4893/4915/5563/51422",10,1.29071827722502
"WP4022","Pyrimidine metabolism","19/1022","79/4839",0.300328097507354,0.999930074063124,0.935607086842689,"790/1841/5167/953/4830/87178/23649/5424/5426/5427/5436/5437/5557/5558/6241/7083/7298/7371/54963",19,1.1861581920904
"WP3298","Melatonin metabolism and effects","7/1022","26/4839",0.301387118348426,0.999930074063124,0.935607086842689,"1408/2308/2932/5187/8864/8863/23411",7,1.37858439201452
"WP3965","Lipid Metabolism Pathway","7/1022","26/4839",0.301387118348426,0.999930074063124,0.935607086842689,"47/10000/2194/29923/5563/51422/5577",7,1.37858439201452
"WP4204","Tumor suppressor activity of SMARCB1","7/1022","26/4839",0.301387118348426,0.999930074063124,0.935607086842689,"86/1019/2146/5928/6597/6598/6602",7,1.37858439201452
"WP129","Matrix Metalloproteinases","6/1022","22/4839",0.313423162273861,0.999930074063124,0.935607086842689,"4312/4320/4321/4322/7078/7079",6,1.4029281496063
"WP4483","Relationship between inflammation, COX-2 and EGFR","6/1022","22/4839",0.313423162273861,0.999930074063124,0.935607086842689,"10000/2099/4312/4893/5733/5734",6,1.4029281496063
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway","15/1022","62/4839",0.321510953260271,0.999930074063124,0.935607086842689,"108/898/1017/1019/1869/1958/2353/2775/54331/3717/4609/5144/5906/5909/8458",15,1.19482769549325
"WP2267","Synaptic Vesicle Pathway","8/1022","31/4839",0.324706678082801,0.999930074063124,0.935607086842689,"477/6571/6581/291/81539/2054/6812/6844",8,1.3014321241746
"WP4148","Splicing factor NOVA regulated synaptic proteins","8/1022","31/4839",0.324706678082801,0.999930074063124,0.935607086842689,"375790/57863/2037/3778/5332/5590/5909/2054",8,1.3014321241746
"WP2882","Nuclear Receptors Meta-Pathway","50/1022","222/4839",0.325747953159628,0.999930074063124,0.935607086842689,"5243/5244/34/11214/330/10486/6347/983/1019/1028/1066/80315/1958/2042/2099/2194/2258/2289/2308/4616/2878/2949/1839/3082/3726/3727/8850/23764/4609/89795/2908/5142/5166/5465/10891/5997/6319/6515/6517/201266/55630/8884/6533/6649/10252/5552/2040/7048/7049/1831",50,1.09011627906977
"WP167","Eicosanoid Synthesis","5/1022","18/4839",0.326479271134302,0.999930074063124,0.935607086842689,"4056/5320/5730/5740/5742",5,1.43862037667347
"WP4286","Genotoxicity pathway","12/1022","49/4839",0.332768133185829,0.999930074063124,0.935607086842689,"59/7832/1052/1062/8161/144455/79733/3398/3708/1263/5734/29950",12,1.21380786727321
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR","7/1022","27/4839",0.338998676265558,0.999930074063124,0.935607086842689,"3066/9759/10014/4772/4776/5532/5533",7,1.30931034482759
"WP3935","Leptin Insulin Overlap","4/1022","14/4839",0.340712611268609,0.999930074063124,0.935607086842689,"3717/3953/8835/9021",4,1.4958742632613
"WP306","Focal Adhesion","39/1022","173/4839",0.349496348233832,0.999930074063124,0.935607086842689,"10000/596/330/857/894/1286/1288/1292/2316/2318/2534/2932/3082/3479/3611/3678/3679/8516/3680/3690/3908/3913/10319/10398/4638/55742/80310/5156/4660/5579/5881/5906/5649/6696/7094/7148/7414/7450/7791",39,1.09045565661013
"WP2881","Estrogen Receptor Pathway","3/1022","10/4839",0.356189265397442,0.999930074063124,0.935607086842689,"2099/5166/5465",3,1.60241132763213
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology","10/1022","41/4839",0.361187936985075,0.999930074063124,0.935607086842689,"108/196883/111/115/1072/4893/6722/23345/7043/7112",10,1.20680861915084
"WP2113","Type III interferon signaling","2/1022","6/4839",0.372163315856723,0.999930074063124,0.935607086842689,"6773/7297",2,1.86911764705882
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ","2/1022","6/4839",0.372163315856723,0.999930074063124,0.935607086842689,"5725/51804",2,1.86911764705882
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk","2/1022","6/4839",0.372163315856723,0.999930074063124,0.935607086842689,"54538/9353",2,1.86911764705882
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging","2/1022","6/4839",0.372163315856723,0.999930074063124,0.935607086842689,"2308/23411",2,1.86911764705882
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex","5/1022","19/4839",0.372981539767396,0.999930074063124,0.935607086842689,"596/1786/1788/1789/6597",5,1.33551060542211
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling","5/1022","19/4839",0.372981539767396,0.999930074063124,0.935607086842689,"2932/4609/5210/5563/6515",5,1.33551060542211
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.","11/1022","46/4839",0.375976615531742,0.999930074063124,0.935607086842689,"596/637/890/898/2252/2353/1839/3569/3726/5156/7186",11,1.17569591634874
"WP28","Selenium Metabolism and Selenoproteins","7/1022","28/4839",0.377156251633749,0.999930074063124,0.935607086842689,"1390/2353/2878/5451/54938/8991/22928",7,1.24663382594417
"WP4481","Resistin as a regulator of inflammation","7/1022","28/4839",0.377156251633749,0.999930074063124,0.935607086842689,"10000/3569/3708/5331/5332/84812/5336",7,1.24663382594417
"WP2366","Butyrate-induced histone acetylation","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"47",1,3.73751224289912
"WP2645","Heroin metabolism","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"1066",1,3.73751224289912
"WP2826","Cocaine metabolism","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"1066",1,3.73751224289912
"WP2943","Hypoxia-mediated EMT and Stemness","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"6935",1,3.73751224289912
"WP4030","SCFA and skeletal muscle substrate metabolism","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"6517",1,3.73751224289912
"WP4284","Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer","1/1022","2/4839",0.377830037928192,0.999930074063124,0.935607086842689,"9134",1,3.73751224289912
"WP2059","Alzheimers Disease","16/1022","69/4839",0.381749900747513,0.999930074063124,0.935607086842689,"6868/322/489/637/775/1020/2906/2932/3708/23385/5331/5332/5532/5533/6263/6622",16,1.12952473836228
"WP3931","ESC Pluripotency Pathways","19/1022","83/4839",0.387246953331721,0.999930074063124,0.935607086842689,"10097/10000/2256/2258/2247/2252/2260/2353/2535/8322/8324/2932/3572/3977/5156/4092/4093/7472/7482",19,1.11083935692921
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer","4/1022","15/4839",0.394062223247433,0.999930074063124,0.935607086842689,"25924/5873/94120/94122",4,1.35952848722986
"WP3287","Overview of nanoparticle effects","4/1022","15/4839",0.394062223247433,0.999930074063124,0.935607086842689,"10000/596/3569/5742",4,1.35952848722986
"WP4462","Platelet-mediated interactions with vascular and circulating cells","4/1022","15/4839",0.394062223247433,0.999930074063124,0.935607086842689,"6347/6401/6403/7043",4,1.35952848722986
"WP1539","Angiogenesis","6/1022","24/4839",0.396750834891395,0.999930074063124,0.935607086842689,"284/2247/4846/5156/7010/7078",6,1.24639107611549
"WP3613","Photodynamic therapy-induced unfolded protein response","6/1022","24/4839",0.396750834891395,0.999930074063124,0.935607086842689,"467/811/51726/7184/10130/23645",6,1.24639107611549
"WP4298","Viral Acute Myocarditis","16/1022","70/4839",0.406170608451993,0.999930074063124,0.935607086842689,"25/596/637/835/857/1676/1677/1756/2534/2932/3569/3908/5881/6442/6443/6444",16,1.10831308445623
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling","7/1022","29/4839",0.415474616467504,0.999930074063124,0.935607086842689,"114907/2932/3479/3488/3611/84557/10891",7,1.18965517241379
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)","3/1022","11/4839",0.419796515080144,0.999930074063124,0.935607086842689,"4609/6422/9839",3,1.40174190382728
"WP4792","Purine metabolism","3/1022","11/4839",0.419796515080144,0.999930074063124,0.935607086842689,"1716/3251/3704",3,1.40174190382728
"WP2261","Signaling Pathways in Glioblastoma","18/1022","80/4839",0.423967332282552,0.999930074063124,0.935607086842689,"10000/672/675/894/898/1017/1019/1869/54206/2260/2308/2956/4893/5156/5336/5579/5590/10253",18,1.08581801824958
"WP4540","Pathways Regulating Hippo Signaling","18/1022","80/4839",0.423967332282552,0.999930074063124,0.935607086842689,"64403/1003/2260/2774/3815/26524/4804/4915/5156/5331/5332/5563/51422/5577/5579/5590/7003/7010",18,1.08581801824958
"WP4249","Hedgehog Signaling Pathway","8/1022","34/4839",0.430894803926012,0.999930074063124,0.935607086842689,"408/596/91653/894/1455/8452/8643/8405",8,1.15035654680625
"WP3303","RAC1/PAK1/p38/MMP2 Pathway","14/1022","62/4839",0.438037685008647,0.999930074063124,0.935607086842689,"284/9068/332/1978/2308/4436/4609/4893/5888/6777/3925/7010/7075/10413",14,1.09056712962963
"WP4008","NO/cGMP/PKG mediated Neuroprotection","6/1022","25/4839",0.438443772084916,0.999930074063124,0.935607086842689,"596/817/2906/4846/4881/5138",6,1.18048072938251
"WP3940","One carbon metabolism and related pathways","9/1022","39/4839",0.444001129236894,0.999930074063124,0.935607086842689,"23743/1036/1788/2571/2878/4524/6472/6649/7298",9,1.12152023692004
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity","4/1022","16/4839",0.44667639799645,0.999930074063124,0.935607086842689,"5243/5244/5465/5914",4,1.24590700720367
"WP4595","Urea cycle and associated pathways","4/1022","16/4839",0.44667639799645,0.999930074063124,0.935607086842689,"162417/5831/10165/10166",4,1.24590700720367
"WP4541","Hippo-Merlin Signaling Dysregulation","21/1022","95/4839",0.446750759963151,0.999930074063124,0.935607086842689,"64403/1003/2260/2305/3678/3679/8516/3680/3690/3815/26524/4609/4804/4893/4915/5156/5332/94274/5577/7003/7010",21,1.06114156114156
"WP4754","IL-18 signaling pathway","48/1022","222/4839",0.453106236341607,0.999930074063124,0.935607086842689,"32/58/59/11096/321/467/596/637/274/330/7832/6347/890/9133/975/2920/1674/2023/2353/1112/2932/3068/26353/3569/3757/10365/84823/9208/4312/4322/4776/3164/51299/5579/5806/8480/22821/23623/9021/10418/6696/83931/3925/6869/7078/7185/10194/80328",48,1.03179211215747
"WP3617","Photodynamic therapy-induced NF-kB survival signaling","7/1022","30/4839",0.453593821400876,0.999930074063124,0.935607086842689,"599/330/332/2920/3569/4312/6401",7,1.1376311844078
"WP1531","Vitamin D Metabolism","2/1022","7/4839",0.453952648610461,0.999930074063124,0.935607086842689,"1593/1717",2,1.49490196078431
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance","2/1022","7/4839",0.453952648610461,0.999930074063124,0.935607086842689,"5243/55384",2,1.49490196078431
"WP3963","Mevalonate pathway","2/1022","7/4839",0.453952648610461,0.999930074063124,0.935607086842689,"39/4598",2,1.49490196078431
"WP4519","Cerebral Organic Acidurias, including diseases","2/1022","7/4839",0.453952648610461,0.999930074063124,0.935607086842689,"137872/501",2,1.49490196078431
"WP399","Wnt Signaling Pathway and Pluripotency","19/1022","86/4839",0.454472351591721,0.999930074063124,0.935607086842689,"894/8061/2535/8322/8324/2932/120892/4609/85407/51701/5048/5516/5521/5579/5590/29127/7472/7482/10009",19,1.06025207958215
"WP3646","Hepatitis C and Hepatocellular Carcinoma","10/1022","44/4839",0.45540496204186,0.999930074063124,0.935607086842689,"330/332/672/1870/2487/3569/3570/4312/4609/6241",10,1.09945361543827
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3","13/1022","58/4839",0.455650588772585,0.999930074063124,0.935607086842689,"817/857/6347/3569/9636/4893/5331/5332/5336/5579/5590/6773/7297",13,1.07996916639137
"WP455","GPCRs, Class A Rhodopsin-like","13/1022","58/4839",0.455650588772585,0.999930074063124,0.935607086842689,"150/154/185/623/624/1909/1910/8477/27198/9934/5733/5734/5737",13,1.07996916639137
"WP2865","IL1 and megakaryocytes in obesity","5/1022","21/4839",0.465289434707419,0.999930074063124,0.935607086842689,"6347/2205/1839/114548/8991",5,1.16795722713864
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)","5/1022","21/4839",0.465289434707419,0.999930074063124,0.935607086842689,"8309/5730/5737/5740/5742",5,1.16795722713864
"WP4225","Pyrimidine metabolism and related diseases","3/1022","12/4839",0.481130404301712,0.999930074063124,0.935607086842689,"790/6241/7298",3,1.2456656853124
"WP3942","PPAR signaling pathway","10/1022","45/4839",0.486552568845093,0.999930074063124,0.935607086842689,"34/8309/1593/2167/2172/3611/4312/5465/6319/10580",10,1.06775832862789
"WP3995","Prion disease pathway","7/1022","31/4839",0.491185904868649,0.999930074063124,0.935607086842689,"596/1879/2260/2534/7184/4208/4684",7,1.08994252873563
"WP3967","miR-509-3p alteration of YAP1/ECM axis","4/1022","17/4839",0.497764149933803,0.999930074063124,0.935607086842689,"1909/10082/7003/10413",4,1.14976575487381
"WP2853","Endoderm Differentiation","24/1022","112/4839",0.505795594256087,0.999930074063124,0.935607086842689,"57198/22943/1789/1847/2146/1112/2308/2627/3087/3251/9682/10459/22823/54892/51701/4830/2908/84295/6422/64321/83595/6925/9760/11169",24,1.0190380761523
"WP3302","eIF5A regulation in response to inhibition of the nuclear export system","1/1022","3/4839",0.509287077671294,0.999930074063124,0.935607086842689,"7514",1,1.86826640548482
"WP4342","Vitamins A and D - action mechanisms","1/1022","3/4839",0.509287077671294,0.999930074063124,0.935607086842689,"5914",1,1.86826640548482
"WP550","Biogenic Amine Synthesis","1/1022","3/4839",0.509287077671294,0.999930074063124,0.935607086842689,"2571",1,1.86826640548482
"WP733","Serotonin Receptor 2 and STAT3 Signaling","1/1022","3/4839",0.509287077671294,0.999930074063124,0.935607086842689,"3717",1,1.86826640548482
"WP364","IL-6 signaling pathway","9/1022","41/4839",0.509627652138112,0.999930074063124,0.935607086842689,"2932/3569/3570/3572/3717/3726/51701/9021/7297",9,1.05086994076999
"WP3878","ATM Signaling Network in Development and Disease ","9/1022","41/4839",0.509627652138112,0.999930074063124,0.935607086842689,"9212/699/983/1020/1111/11200/9759/3150/5591",9,1.05086994076999
"WP2911","miRNA targets in ECM and membrane receptors","5/1022","22/4839",0.509955985423171,0.999930074063124,0.935607086842689,"1291/1292/3913/6383/7148",5,1.09896465961016
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome","5/1022","22/4839",0.509955985423171,0.999930074063124,0.935607086842689,"11335/1869/3066/23028/5928",5,1.09896465961016
"WP4357","NRF2-ARE regulation","5/1022","22/4839",0.509955985423171,0.999930074063124,0.935607086842689,"8452/2048/2534/2932/192111",5,1.09896465961016
"WP465","Tryptophan metabolism","6/1022","27/4839",0.519721365903094,0.999930074063124,0.935607086842689,"38/217/316/23498/11185/4129",6,1.06749156355456
"WP2034","Leptin signaling pathway","16/1022","75/4839",0.527975666140062,0.999930074063124,0.935607086842689,"32/1073/1978/2099/2308/2534/2932/3717/3953/4846/5140/5336/5563/8835/9021/6777",16,1.01304040165785
"WP1423","Ganglio Sphingolipid Metabolism","2/1022","8/4839",0.52923088244051,0.999930074063124,0.935607086842689,"30815/6489",2,1.24542483660131
"WP2007","Iron metabolism in placenta","2/1022","8/4839",0.52923088244051,0.999930074063124,0.935607086842689,"55240/7037",2,1.24542483660131
"WP3585","Cytosine methylation","2/1022","8/4839",0.52923088244051,0.999930074063124,0.935607086842689,"1786/4204",2,1.24542483660131
"WP561","Heme Biosynthesis","2/1022","8/4839",0.52923088244051,0.999930074063124,0.935607086842689,"1371/3145",2,1.24542483660131
"WP3941","Oxidative Damage","8/1022","37/4839",0.535146493773912,0.999930074063124,0.935607086842689,"596/715/716/1028/5111/7133/7185/7186",8,1.03053798544515
"WP4312","Rett syndrome causing genes","8/1022","37/4839",0.535146493773912,0.999930074063124,0.935607086842689,"2775/10014/10765/4204/4208/6597/6812/6925",8,1.03053798544515
"WP4673","Genes involved in male infertility","18/1022","85/4839",0.538343473407803,0.999930074063124,0.935607086842689,"5243/3983/596/675/1191/2099/2775/222229/4524/340719/4846/143689/8787/6649/9319/7320/7516/7517",18,1.00344889100315
"WP1434","Osteopontin Signaling","3/1022","13/4839",0.539193661021595,0.999930074063124,0.935607086842689,"3690/9020/6696",3,1.12080471050049
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness","3/1022","13/4839",0.539193661021595,0.999930074063124,0.935607086842689,"3690/8076/6263",3,1.12080471050049
"WP3853","ERK Pathway in Huntington's Disease","3/1022","13/4839",0.539193661021595,0.999930074063124,0.935607086842689,"627/4915/9252",3,1.12080471050049
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism","14/1022","66/4839",0.541760028083866,0.999930074063124,0.935607086842689,"10000/2260/2308/2932/3690/23028/11343/4881/10891/63976/9728/6567/7067/8458",14,1.00560897435897
"WP1742","TP53 Network","4/1022","18/4839",0.546702686733661,0.999930074063124,0.935607086842689,"25/596/637/4609",4,1.0673589671625
"WP1544","MicroRNAs in cardiomyocyte hypertrophy","16/1022","76/4839",0.551661136773016,0.999930074063124,0.935607086842689,"817/2247/2535/2932/9759/10014/3479/3572/9020/4638/4776/5320/5532/5579/5592/1827",16,0.995891318754142
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease","5/1022","23/4839",0.553022481857523,0.999930074063124,0.935607086842689,"185/2201/2316/7048/7049",5,1.03763793291817
"WP3929","Chemokine signaling pathway","26/1022","124/4839",0.5530567389186,0.999930074063124,0.935607086842689,"108/196883/111/115/10000/408/6366/6376/6387/9844/2791/55970/54331/2788/2869/2932/3717/4893/5331/5332/5579/5590/5906/10235/6773/6777",26,0.990636013441521
"WP4561","Cell migration and invasion through p75NTR","6/1022","28/4839",0.558602760703824,0.999930074063124,0.935607086842689,"10000/627/1944/1945/4804/4915",6,1.01870078740157
"WP4756","Renin Angiotensin Aldosterone System (RAAS)","6/1022","28/4839",0.558602760703824,0.999930074063124,0.935607086842689,"185/817/90993/9586/1511/3708",6,1.01870078740157
"WP363","Wnt Signaling Pathway (Netpath)","10/1022","48/4839",0.576782391898208,0.999930074063124,0.935607086842689,"2932/4609/51701/8395/5579/4919/4920/6929/6925/7010",10,0.982681506136884
"WP3888","VEGFA-VEGFR2 Signaling Pathway","84/1022","403/4839",0.577632731826315,0.999930074063124,0.935607086842689,"25/32/52/9510/56999/154/81575/22899/51309/596/274/332/781/811/857/6347/10574/1003/1072/84952/79094/22820/1397/1465/22943/11080/1847/1958/1960/2048/2078/2308/6624/2534/2932/1839/9759/10014/10525/3690/9365/9079/3984/4208/4343/4629/91624/4772/4846/3164/4929/8013/55872/57326/10130/5331/5496/5563/5579/5590/5592/5717/326624/5906/1827/10231/57381/9252/1901/6386/23753/6401/114789/6546/6722/6747/10963/6886/7111/8718/7148/7170/7220/7414",84,0.981986618630983
"WP2857","Mesodermal Commitment Pathway","24/1022","116/4839",0.583056439508221,0.999930074063124,0.935607086842689,"84159/57198/22943/1789/2260/8322/2627/3251/3624/3717/9314/4211/22823/54892/51701/84295/5308/64321/6722/6925/7003/9760/11169/10413",24,0.973686503441666
"WP3580","Methionine De Novo and Salvage Pathway","4/1022","19/4839",0.593028325924665,0.999930074063124,0.935607086842689,"191/4482/253827/4953",4,0.995939751146038
"WP197","Cholesterol Biosynthesis Pathway","3/1022","14/4839",0.593324856408773,0.999930074063124,0.935607086842689,"1717/4598/6713",3,1.01864573110893
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity","3/1022","14/4839",0.593324856408773,0.999930074063124,0.935607086842689,"1019/1869/6659",3,1.01864573110893
"WP4558","Overview of interferons-mediated signaling pathway","3/1022","14/4839",0.593324856408773,0.999930074063124,0.935607086842689,"3717/6773/7297",3,1.01864573110893
"WP530","Cytokines and Inflammatory Response","3/1022","14/4839",0.593324856408773,0.999930074063124,0.935607086842689,"1440/2920/3569",3,1.01864573110893
"WP26","Signal Transduction of S1P Receptor","5/1022","24/4839",0.594146599480189,0.999930074063124,0.935607086842689,"10000/5331/29127/1901/9294",5,0.982766651141127
"WP3972","PDGFR-beta pathway","6/1022","29/4839",0.595940537461125,0.999930074063124,0.935607086842689,"5610/2353/3717/5579/6722/6777",6,0.97415268743581
"WP2436","Dopamine metabolism","2/1022","9/4839",0.597098605568243,0.999930074063124,0.935607086842689,"4129/5516",2,1.0672268907563
"WP3930","EDA Signalling in Hair Follicle Development","2/1022","9/4839",0.597098605568243,0.999930074063124,0.935607086842689,"22943/128178",2,1.0672268907563
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders","2/1022","9/4839",0.597098605568243,0.999930074063124,0.935607086842689,"191/1036",2,1.0672268907563
"WP4290","Metabolic reprogramming in colon cancer","8/1022","39/4839",0.600413887507652,0.999930074063124,0.935607086842689,"47/2023/2194/2618/10606/5471/5831/6472",8,0.963542660813132
"WP51","Regulation of Actin Cytoskeleton","24/1022","117/4839",0.601698390294853,0.999930074063124,0.935607086842689,"9459/623/624/1072/1073/26999/81624/2256/2258/2247/2252/2260/28964/55970/2934/3984/4638/4893/5156/5305/8395/5881/6237/7414",24,0.962958174413343
"WP1604","Codeine and Morphine Metabolism","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"5243",1,1.24518445968005
"WP2289","Drug Induction of Bile Acid Pathway","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"5243",1,1.24518445968005
"WP3924","Hfe effect on hepcidin production","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"4092",1,1.24518445968005
"WP4228","Vitamin B6-dependent and responsive disorders","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"501",1,1.24518445968005
"WP4399","MicroRNA network associated with chronic lymphocytic leukemia","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"596",1,1.24518445968005
"WP4524","The alternative pathway of fetal androgen synthesis","1/1022","4/4839",0.61299026349014,0.999930074063124,0.935607086842689,"8630",1,1.24518445968005
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway","8/1022","40/4839",0.631256528279167,0.999930074063124,0.935607086842689,"330/6347/2932/3569/9020/8742/7185/7186",8,0.93318540433925
"WP2332","Interleukin-11 Signaling Pathway","8/1022","40/4839",0.631256528279167,0.999930074063124,0.935607086842689,"596/332/2534/3590/3572/3717/9021/7297",8,0.93318540433925
"WP2586","Aryl Hydrocarbon Receptor Netpath","8/1022","40/4839",0.631256528279167,0.999930074063124,0.935607086842689,"1017/1869/2099/1316/4609/135112/4893/84722",8,0.93318540433925
"WP1533","Vitamin B12 Metabolism","6/1022","30/4839",0.631527216476187,0.999930074063124,0.935607086842689,"6347/3569/4524/12/6472/6649",6,0.933316929133858
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities","6/1022","30/4839",0.631527216476187,0.999930074063124,0.935607086842689,"1978/2308/2932/4846/4893/7942",6,0.933316929133858
"WP1424","Globo Sphingolipid Metabolism","4/1022","20/4839",0.636421369543438,0.999930074063124,0.935607086842689,"256435/27090/30815/6489",4,0.933447937131631
"WP262","EBV LMP1 signaling","4/1022","20/4839",0.636421369543438,0.999930074063124,0.935607086842689,"9020/4215/9260/7185",4,0.933447937131631
"WP357","Fatty Acid Biosynthesis","4/1022","20/4839",0.636421369543438,0.999930074063124,0.935607086842689,"32/47/2194/6319",4,0.933447937131631
"WP254","Apoptosis","16/1022","80/4839",0.64167988935281,0.999930074063124,0.935607086842689,"596/599/637/330/332/835/1676/1677/3070/3479/3663/4609/7133/8718/7185/7186",16,0.93265407554672
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling","3/1022","15/4839",0.643140514699108,0.999930074063124,0.935607086842689,"3708/4893/6722",3,0.93351324828263
"WP2333","Trans-sulfuration pathway","2/1022","10/4839",0.657325940610943,0.999930074063124,0.935607086842689,"191/1786",2,0.933578431372549
"WP3630","NAD metabolism, sirtuins and aging","2/1022","10/4839",0.657325940610943,0.999930074063124,0.935607086842689,"2308/23411",2,0.933578431372549
"WP3892","Development of pulmonary dendritic cells and macrophage subsets","2/1022","10/4839",0.657325940610943,0.999930074063124,0.935607086842689,"3398/6925",2,0.933578431372549
"WP3971","Role of Osx and miRNAs in tooth development","2/1022","10/4839",0.657325940610943,0.999930074063124,0.935607086842689,"22943/9314",2,0.933578431372549
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma","11/1022","56/4839",0.659389444502175,0.999930074063124,0.935607086842689,"84159/672/1111/11200/93986/9863/4602/4609/4781/5591/29128",11,0.91201230904495
"WP560","TGF-beta Receptor Signaling","9/1022","46/4839",0.659799833104285,0.999930074063124,0.935607086842689,"2353/3624/4092/4093/6696/7048/7049/9839/23090",9,0.907659881006377
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)","8/1022","41/4839",0.660742316434575,0.999930074063124,0.935607086842689,"9023/1593/1717/10682/2194/4598/6319/6713",8,0.904667981591059
"WP2371","Parkinsons Disease Pathway","6/1022","31/4839",0.665209131261997,0.999930074063124,0.935607086842689,"835/898/9134/120892/6622/23208",6,0.895748031496063
"WP3527","Preimplantation Embryo","6/1022","31/4839",0.665209131261997,0.999930074063124,0.935607086842689,"1958/2354/9314/4306/6597/7538",6,0.895748031496063
"WP619","Type II interferon signaling (IFNG)","6/1022","31/4839",0.665209131261997,0.999930074063124,0.935607086842689,"5610/2537/9636/3717/9021/6773",6,0.895748031496063
"WP4262","Breast cancer pathway","24/1022","121/4839",0.672534826004334,0.999930074063124,0.935607086842689,"10000/672/675/1019/1457/1869/1870/2099/2247/2252/2260/2353/2535/8324/4616/2932/3479/3815/4609/4893/5241/5888/7472/7482",24,0.922256884903828
"WP4482","Vitamin D in inflammatory diseases","4/1022","21/4839",0.676687707151914,0.999930074063124,0.935607086842689,"1843/3569/4772/2908",4,0.878308101236565
"WP138","Androgen receptor signaling pathway","16/1022","82/4839",0.683077882553455,0.999930074063124,0.935607086842689,"672/811/857/898/11034/2288/2316/2308/2932/8850/23028/5883/5901/388/23411/7041",16,0.903909874088801
"WP107","Translation Factors","9/1022","47/4839",0.68642269962721,0.999930074063124,0.935607086842689,"1915/1933/1936/27102/5610/1975/1978/1979/8637",9,0.883540291993557
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ","3/1022","16/4839",0.688478387784337,0.999930074063124,0.935607086842689,"2146/22823/5928",3,0.86147807050653
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds","3/1022","16/4839",0.688478387784337,0.999930074063124,0.935607086842689,"8324/2932/6925",3,0.86147807050653
"WP3927","BMP Signaling Pathway in Eyelid Development","3/1022","16/4839",0.688478387784337,0.999930074063124,0.935607086842689,"3625/5308/6422",3,0.86147807050653
"WP4331","Neovascularisation processes","7/1022","37/4839",0.692135111733692,0.999930074063124,0.935607086842689,"94/284/6387/2048/3815/4093/7043",7,0.870574712643678
"WP2805","exRNA mechanism of action and biogenesis","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"57510",1,0.933643486777669
"WP311","Synthesis and Degradation of Ketone Bodies","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"38",1,0.933643486777669
"WP3596","miR-517 relationship with ARCN1 and USP1","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"3398",1,0.933643486777669
"WP4147","PTF1A related regulatory pathway","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"8850",1,0.933643486777669
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"79017",1,0.933643486777669
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase","1/1022","5/4839",0.694794596626247,0.999930074063124,0.935607086842689,"2053",1,0.933643486777669
"WP2870","Extracellular vesicle-mediated signaling in recipient cells","5/1022","27/4839",0.703691151331918,0.999930074063124,0.935607086842689,"3082/4893/7043/7048/7049",5,0.848082595870207
"WP4150","Wnt Signaling in Kidney Disease","5/1022","27/4839",0.703691151331918,0.999930074063124,0.935607086842689,"2535/8322/8324/7472/7482",5,0.848082595870207
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway","24/1022","123/4839",0.705339946522517,0.999930074063124,0.935607086842689,"32/6868/627/1020/1072/1457/1808/1958/1959/1978/2353/2534/2932/3717/4208/4684/4776/4804/4915/5563/5906/9252/6696/6777",24,0.90313961255845
"WP4239","Epithelial to mesenchymal transition in colorectal cancer","25/1022","128/4839",0.706030484524258,0.999930074063124,0.935607086842689,"10000/5010/7122/1286/1288/2146/2305/2535/8322/8324/2932/3398/3678/26524/4209/5310/5928/7043/7048/117581/7472/7482/7483/6935/9839",25,0.904168817131005
"WP2290","RalA downstream regulated genes","2/1022","11/4839",0.710110257395565,0.999930074063124,0.935607086842689,"4893/5881",2,0.82962962962963
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ","2/1022","11/4839",0.710110257395565,0.999930074063124,0.935607086842689,"3569/6773",2,0.82962962962963
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma","2/1022","11/4839",0.710110257395565,0.999930074063124,0.935607086842689,"2146/84759",2,0.82962962962963
"WP4629","Computational Model of Aerobic Glycolysis","2/1022","11/4839",0.710110257395565,0.999930074063124,0.935607086842689,"2023/7167",2,0.82962962962963
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway","4/1022","22/4839",0.713739200869411,0.999930074063124,0.935607086842689,"374/627/1978/2308",4,0.829294913774285
"WP716","Vitamin A and Carotenoid Metabolism","4/1022","22/4839",0.713739200869411,0.999930074063124,0.935607086842689,"83875/5914/5947/116362",4,0.829294913774285
"WP127","IL-5 Signaling Pathway","7/1022","38/4839",0.720091281028044,0.999930074063124,0.935607086842689,"596/695/2353/2932/3717/4609/6777",7,0.842269187986652
"WP2828","Bladder Cancer","7/1022","38/4839",0.720091281028044,0.999930074063124,0.935607086842689,"1019/1869/1839/4312/4609/4893/9252",7,0.842269187986652
"WP2875","Constitutive Androstane Receptor Pathway","3/1022","17/4839",0.729345724466594,0.999930074063124,0.935607086842689,"5243/2308/10891",3,0.79973363241273
"WP3645","NAD+ biosynthetic pathways","3/1022","17/4839",0.729345724466594,0.999930074063124,0.935607086842689,"683/10038/23411",3,0.79973363241273
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway","3/1022","17/4839",0.729345724466594,0.999930074063124,0.935607086842689,"2252/5310/23411",3,0.79973363241273
"WP4747","Netrin-UNC5B signaling Pathway","8/1022","44/4839",0.740317238416276,0.999930074063124,0.935607086842689,"6347/1003/2534/9423/56963/54538/6401/10413",8,0.828621520929213
"WP12","Osteoclast Signaling","2/1022","12/4839",0.755906228014336,0.999930074063124,0.935607086842689,"3690/6696",2,0.746470588235294
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ","2/1022","12/4839",0.755906228014336,0.999930074063124,0.935607086842689,"9020/6237",2,0.746470588235294
"WP4724","Omega-9 FA synthesis","2/1022","12/4839",0.755906228014336,0.999930074063124,0.935607086842689,"2194/6319",2,0.746470588235294
"WP15","Selenium Micronutrient Network","9/1022","50/4839",0.758229156843588,0.999930074063124,0.935607086842689,"6347/80308/2878/3569/4524/5742/22928/12/6649",9,0.818240916861291
"WP2249","Metastatic brain tumor","1/1022","6/4839",0.759320852780151,0.999930074063124,0.935607086842689,"4609",1,0.746718903036239
"WP2456","HIF1A and PPARG regulation of glycolysis","1/1022","6/4839",0.759320852780151,0.999930074063124,0.935607086842689,"7167",1,0.746718903036239
"WP2485","NAD Biosynthesis II (from tryptophan)","1/1022","6/4839",0.759320852780151,0.999930074063124,0.935607086842689,"23498",1,0.746718903036239
"WP3655","Hypothetical Craniofacial Development Pathway","1/1022","6/4839",0.759320852780151,0.999930074063124,0.935607086842689,"7043",1,0.746718903036239
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ","13/1022","71/4839",0.763504992842297,0.999930074063124,0.935607086842689,"10000/596/332/2353/4616/2932/4436/2956/4609/9423/5881/7043/7048",13,0.83501930897782
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway","8/1022","45/4839",0.763755951174917,0.999930074063124,0.935607086842689,"695/1978/2534/3569/3717/4609/6777/85480",8,0.806013113705421
"WP408","Oxidative Stress","5/1022","29/4839",0.764251182556945,0.999930074063124,0.935607086842689,"2353/2878/3726/4784/6649",5,0.776999344477221
"WP2876","Pregnane X Receptor pathway","3/1022","18/4839",0.765874332013181,0.999930074063124,0.935607086842689,"5243/2308/10891",3,0.746221786064769
"WP404","Nucleotide Metabolism","3/1022","18/4839",0.765874332013181,0.999930074063124,0.935607086842689,"3251/5424/6241",3,0.746221786064769
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells","3/1022","18/4839",0.765874332013181,0.999930074063124,0.935607086842689,"4893/5873/6237",3,0.746221786064769
"WP4533","Transcription co-factors SKI and SKIL protein partners","3/1022","18/4839",0.765874332013181,0.999930074063124,0.935607086842689,"26524/4204/7003",3,0.746221786064769
"WP268","Notch Signaling","7/1022","40/4839",0.77066765868094,0.999930074063124,0.935607086842689,"6868/151636/3066/2648/8850/4242/23385",7,0.790804597701149
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation","7/1022","40/4839",0.77066765868094,0.999930074063124,0.935607086842689,"58/596/1676/1677/4001/84823/5591",7,0.790804597701149
"WP185","Integrin-mediated Cell Adhesion","16/1022","87/4839",0.773755263751992,0.999930074063124,0.935607086842689,"10000/857/2534/3611/3678/3679/8516/3680/3690/5881/5906/10580/7094/7145/7414/7791",16,0.839134208831518
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling","10/1022","56/4839",0.774278860742701,0.999930074063124,0.935607086842689,"32/890/891/1978/2194/3953/133522/5563/51422/6517",10,0.810061866300052
"WP3529","Zinc homeostasis","4/1022","24/4839",0.77825983963447,0.999930074063124,0.935607086842689,"4499/55676/201266/55630",4,0.745972495088409
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation","4/1022","24/4839",0.77825983963447,0.999930074063124,0.935607086842689,"4882/5745/5933/7067",4,0.745972495088409
"WP366","TGF-beta Signaling Pathway","24/1022","128/4839",0.778583806473659,0.999930074063124,0.935607086842689,"467/857/9133/983/2353/2354/3690/3726/3727/7071/1316/4208/4312/4321/4609/5933/4092/7027/7041/7048/7049/10413/6935/9839",24,0.858563280406968
"WP2795","Cardiac Hypertrophic Response","9/1022","51/4839",0.779407731793952,0.999930074063124,0.935607086842689,"817/2247/2932/9759/10014/3479/9020/5320/5592",9,0.798547454519814
"WP524","G13 Signaling Pathway","6/1022","35/4839",0.779438941079249,0.999930074063124,0.935607086842689,"1072/1073/11113/3984/5305/6242",6,0.771382025522672
"WP2328","Allograft Rejection","11/1022","62/4839",0.78878849901806,0.999930074063124,0.935607086842689,"5243/185/23743/718/730/6366/6387/120892/5156/5590/7431",11,0.803436706037509
"WP2369","Histone Modifications","5/1022","30/4839",0.790795975773096,0.999930074063124,0.935607086842689,"2146/26040/80854/9869/56950",5,0.745722713864307
"WP2447","Amyotrophic lateral sclerosis (ALS)","5/1022","30/4839",0.790795975773096,0.999930074063124,0.935607086842689,"596/637/1471/5532/5533",5,0.745722713864307
"WP49","IL-2 Signaling Pathway","7/1022","41/4839",0.793299346790486,0.999930074063124,0.935607086842689,"596/894/2353/2534/4609/9021/6777",7,0.767342799188641
"WP4504","Cysteine and methionine catabolism","2/1022","13/4839",0.795308512922107,0.999930074063124,0.935607086842689,"191/1036",2,0.67843137254902
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing","2/1022","13/4839",0.795308512922107,0.999930074063124,0.935607086842689,"103/10535",2,0.67843137254902
"WP585","Interferon type I signaling pathways","9/1022","52/4839",0.799212112621598,0.999930074063124,0.935607086842689,"1975/1978/2534/27250/5906/9252/9021/6773/7297",9,0.779769967170963
"WP4565","Neural Crest Cell Migration in Cancer","6/1022","36/4839",0.802839816817109,0.999930074063124,0.935607086842689,"10000/627/2048/2353/4804/4915",6,0.745472440944882
"WP205","IL-7 Signaling Pathway","4/1022","25/4839",0.80591460788313,0.999930074063124,0.935607086842689,"2534/2932/4609/6777",4,0.710262887080176
"WP106","Alanine and aspartate metabolism","1/1022","7/4839",0.8102155534751,0.999930074063124,0.935607086842689,"2571",1,0.622102513875286
"WP229","Irinotecan Pathway","1/1022","7/4839",0.8102155534751,0.999930074063124,0.935607086842689,"1066",1,0.622102513875286
"WP4236","Disorders of the Krebs cycle","1/1022","7/4839",0.8102155534751,0.999930074063124,0.935607086842689,"55526",1,0.622102513875286
"WP4507","Molybdenum cofactor (Moco) biosynthesis","1/1022","7/4839",0.8102155534751,0.999930074063124,0.935607086842689,"316",1,0.622102513875286
"WP704","Methylation Pathways","1/1022","7/4839",0.8102155534751,0.999930074063124,0.935607086842689,"11185",1,0.622102513875286
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions","5/1022","31/4839",0.814947292025231,0.999930074063124,0.935607086842689,"2308/26524/5906/7003/10413",5,0.716851977913925
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)","3/1022","20/4839",0.82684676790972,0.999930074063124,0.935607086842689,"8309/4056/5465",3,0.658084627374011
"WP4725","Sphingolipid Metabolism (general overview)","3/1022","20/4839",0.82684676790972,0.999930074063124,0.935607086842689,"29956/166929/6609",3,0.658084627374011
"WP304","Kit receptor signaling pathway","10/1022","59/4839",0.828430322217722,0.999930074063124,0.935607086842689,"596/695/2353/2534/3717/3726/3815/4286/5579/6777",10,0.759861256755667
"WP1584","Type II diabetes mellitus","2/1022","14/4839",0.828972455674329,0.999930074063124,0.935607086842689,"5590/6517",2,0.621732026143791
"WP1946","Cori Cycle","2/1022","14/4839",0.828972455674329,0.999930074063124,0.935607086842689,"6517/7167",2,0.621732026143791
"WP3644","NAD+ metabolism","2/1022","14/4839",0.828972455674329,0.999930074063124,0.935607086842689,"4907/23411",2,0.621732026143791
"WP2884","NRF2 pathway","17/1022","96/4839",0.829421211575612,0.999930074063124,0.935607086842689,"1066/1958/2042/2258/2878/2949/1839/3082/23764/6515/6517/201266/55630/8884/6533/6649/7048",17,0.800377857547705
"WP3981","miRNA regulation of prostate cancer signaling pathways","5/1022","32/4839",0.836811213554681,0.999930074063124,0.935607086842689,"10000/596/90993/2308/2932",5,0.690119814996904
"WP673","ErbB Signaling Pathway","14/1022","81/4839",0.839063333601451,0.999930074063124,0.935607086842689,"25/10000/374/817/1978/2308/2932/1839/4609/4893/9542/5336/5579/6777",14,0.777363184079602
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"4524",1,0.533090807331748
"WP288","NLR Proteins","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"2048",1,0.533090807331748
"WP3634","Insulin signalling in human adipocytes (normal condition)","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"6517",1,0.533090807331748
"WP3635","Insulin signalling in human adipocytes (diabetic condition)","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"6517",1,0.533090807331748
"WP3871","Valproic acid pathway","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"36",1,0.533090807331748
"WP3934","Leptin and adiponectin","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"3953",1,0.533090807331748
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"3569",1,0.533090807331748
"WP4742","Ketogenesis and Ketolysis","1/1022","8/4839",0.850356220765755,0.999930074063124,0.935607086842689,"38",1,0.533090807331748
"WP286","IL-3 Signaling Pathway","7/1022","44/4839",0.851044950413995,0.999930074063124,0.935607086842689,"596/969/2353/2534/3563/3717/6777",7,0.704566635601118
"WP2509","Nanoparticle triggered autophagic cell death","3/1022","21/4839",0.851873278036022,0.999930074063124,0.935607086842689,"596/10036/84557",3,0.621360811252862
"WP4726","Sphingolipid Metabolism (integrated pathway)","3/1022","21/4839",0.851873278036022,0.999930074063124,0.935607086842689,"29956/166929/6609",3,0.621360811252862
"WP712","Estrogen signaling pathway","3/1022","21/4839",0.851873278036022,0.999930074063124,0.935607086842689,"596/2099/2353",3,0.621360811252862
"WP2112","IL17 signaling pathway","4/1022","27/4839",0.852782578619521,0.999930074063124,0.935607086842689,"1052/2932/3717/9020",4,0.648159220978902
"WP437","EGF/EGFR Signaling Pathway","28/1022","155/4839",0.853072181335939,0.999930074063124,0.935607086842689,"25/6790/857/1072/1869/1978/54206/2353/2354/2308/3717/3727/4215/4208/4209/4605/4846/5111/5579/5590/5906/6196/9252/10253/10617/6777/3925/6812",28,0.81845403127426
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling","5/1022","33/4839",0.856512069472329,0.999930074063124,0.935607086842689,"284/637/332/6515/7043",5,0.665297092288243
"WP400","p38 MAPK Signaling Pathway","5/1022","33/4839",0.856512069472329,0.999930074063124,0.935607086842689,"3150/4209/4609/9252/7186",5,0.665297092288243
"WP422","MAPK Cascade","5/1022","33/4839",0.856512069472329,0.999930074063124,0.935607086842689,"4215/4893/5331/22821/6237",5,0.665297092288243
"WP4564","Neural Crest Cell Migration during Development","5/1022","33/4839",0.856512069472329,0.999930074063124,0.935607086842689,"10000/627/2048/2353/4804",5,0.665297092288243
"WP4758","Nephrotic syndrome","5/1022","33/4839",0.856512069472329,0.999930074063124,0.935607086842689,"54443/83478/1286/3913/11346",5,0.665297092288243
"WP615","Senescence and Autophagy in Cancer","16/1022","93/4839",0.856950684897775,0.999930074063124,0.935607086842689,"596/1869/23710/2932/2934/3479/3488/3569/3570/3572/3624/3663/84557/81631/5111/55630",16,0.77250781028117
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus","2/1022","15/4839",0.857561985055132,0.999930074063124,0.935607086842689,"166929/256435",2,0.573755656108597
"WP430","Statin Pathway","2/1022","15/4839",0.857561985055132,0.999930074063124,0.935607086842689,"341/6713",2,0.573755656108597
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer","8/1022","50/4839",0.858253018221591,0.999930074063124,0.935607086842689,"25/332/3070/3727/4092/9021/7185/7431",8,0.709119939889171
"WP231","TNF alpha Signaling Pathway","15/1022","88/4839",0.860413949541904,0.999930074063124,0.935607086842689,"637/330/6347/1457/3569/9020/4215/1326/4893/5347/5590/6401/7133/7185/7186",15,0.763967297411272
"WP4566","Translation inhibitors in chronically activated PDGFRA cells","7/1022","45/4839",0.867124502905404,0.999930074063124,0.935607086842689,"10000/1457/1975/1978/27250/6196/9252",7,0.685843920145191
"WP2643","Nanoparticle-mediated activation of receptor signaling","4/1022","28/4839",0.872374324086727,0.999930074063124,0.935607086842689,"10000/374/4893/7094",4,0.620988867059594
"WP4223","Ras Signaling","25/1022","142/4839",0.875522194317694,0.999930074063124,0.935607086842689,"25/10000/2260/2791/55970/54331/2788/3815/4804/4893/4915/5156/5320/8605/5336/5579/5881/5906/22821/10156/8437/10235/23179/6237/7010",25,0.792977222265086
"WP1772","Apoptosis Modulation and Signaling","13/1022","79/4839",0.879929154875462,0.999930074063124,0.935607086842689,"9531/596/599/637/330/332/835/1676/1677/2353/9020/7133/8718",13,0.732243145028081
"WP3413","NOTCH1 regulation of human endothelial cell calcification","2/1022","16/4839",0.881716784665246,0.999930074063124,0.935607086842689,"1902/4256",2,0.532633053221289
"WP391","Mitochondrial Gene Expression","2/1022","16/4839",0.881716784665246,0.999930074063124,0.935607086842689,"10891/133522",2,0.532633053221289
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1","1/1022","9/4839",0.882013422665444,0.999930074063124,0.935607086842689,"23764",1,0.466332027424094
"WP698","Glucuronidation","1/1022","9/4839",0.882013422665444,0.999930074063124,0.935607086842689,"5239",1,0.466332027424094
"WP411","mRNA Processing","21/1022","122/4839",0.883577816383176,0.999930074063124,0.935607086842689,"10659/1196/29894/51692/1478/9343/3191/56339/4841/5496/55660/5725/6626/6628/6632/6635/6636/6637/8405/10772/6430",21,0.771861801564772
"WP4685","Melanoma","10/1022","63/4839",0.88442190556457,0.999930074063124,0.935607086842689,"10000/1019/1869/1870/2353/4616/3815/4286/4893/7414",10,0.701767469609964
"WP4197","The human immune response to tuberculosis","3/1022","23/4839",0.892600365127733,0.999930074063124,0.935607086842689,"3717/6773/7297",3,0.558930323846909
"WP4537","Hippo-Yap signaling pathway","3/1022","23/4839",0.892600365127733,0.999930074063124,0.935607086842689,"26524/7003/23043",3,0.558930323846909
"WP3286","Copper homeostasis","7/1022","47/4839",0.89500690547911,0.999930074063124,0.935607086842689,"6868/2308/2932/22823/6649/55240/79689",7,0.651206896551724
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits","2/1022","17/4839",0.902032926025066,0.999930074063124,0.935607086842689,"7428/7472",2,0.496993464052288
"WP4155","Endometrial cancer","9/1022","59/4839",0.902327265856976,0.999930074063124,0.935607086842689,"10000/2247/2260/2353/4616/2932/3611/4609/4893",9,0.669358341559724
"WP500","Glycogen Synthesis and Degradation","5/1022","36/4839",0.904032070792873,0.999930074063124,0.935607086842689,"2932/5516/5521/5525/5837",5,0.600437720049481
"WP3676","BDNF-TrkB Signaling","4/1022","30/4839",0.904886034571245,0.999930074063124,0.935607086842689,"627/1978/4893/4915",4,0.572918240894665
"WP4241","Type 2 papillary renal cell carcinoma","4/1022","30/4839",0.904886034571245,0.999930074063124,0.935607086842689,"81578/7942/7043/7428",4,0.572918240894665
"WP43","Oxidation by Cytochrome P450","4/1022","30/4839",0.904886034571245,0.999930074063124,0.935607086842689,"1727/57404/1593/51302",4,0.572918240894665
"WP4496","Signal transduction through IL1R","4/1022","30/4839",0.904886034571245,0.999930074063124,0.935607086842689,"3569/11213/9020/7043",4,0.572918240894665
"WP4666","Hepatitis B infection","22/1022","130/4839",0.905470089093815,0.999930074063124,0.935607086842689,"10000/596/637/332/90993/9586/1959/1960/2353/3569/3717/4609/4772/4776/4893/5111/5579/6773/6777/7043/7048/7297",22,0.755537037037037
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation","1/1022","10/4839",0.906978698449278,0.999930074063124,0.935607086842689,"10766",1,0.414408531940363
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B","1/1022","10/4839",0.906978698449278,0.999930074063124,0.935607086842689,"5590",1,0.414408531940363
"WP438","Non-homologous end joining","1/1022","10/4839",0.906978698449278,0.999930074063124,0.935607086842689,"5591",1,0.414408531940363
"WP1422","Sphingolipid pathway","3/1022","24/4839",0.908934725912484,0.999930074063124,0.935607086842689,"29956/57515/166929",3,0.532174400672929
"WP2636","Common Pathways Underlying Drug Addiction","3/1022","24/4839",0.908934725912484,0.999930074063124,0.935607086842689,"72/5579/5906",3,0.532174400672929
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment","3/1022","24/4839",0.908934725912484,0.999930074063124,0.935607086842689,"6347/7043/7048",3,0.532174400672929
"WP3925","Amino Acid metabolism","10/1022","66/4839",0.915791648477362,0.999930074063124,0.935607086842689,"34/47/126/5832/501/8639/790/4953/5166/5831",10,0.663643421795596
"WP4659","Gastrin Signaling Pathway","17/1022","105/4839",0.918594120239461,0.999930074063124,0.935607086842689,"408/330/332/1958/1978/2353/2308/2534/2932/3717/3815/9314/4208/4209/4609/388/6925",17,0.716791044776119
"WP384","Apoptosis Modulation by HSP70","2/1022","18/4839",0.919052750276552,0.999930074063124,0.935607086842689,"637/835",2,0.465808823529412
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression","2/1022","18/4839",0.919052750276552,0.999930074063124,0.935607086842689,"1978/55872",2,0.465808823529412
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways","8/1022","55/4839",0.919649796928562,0.999930074063124,0.935607086842689,"58/10097/2535/8322/8324/2932/4609/4638",8,0.632842334969995
"WP4521","Glycosylation and related congenital defects","3/1022","25/4839",0.922982923825578,0.999930074063124,0.935607086842689,"10195/79053/7841",3,0.507850834151129
"WP4255","Non-small cell lung cancer","10/1022","67/4839",0.924503025461715,0.999930074063124,0.935607086842689,"10000/637/1019/1869/1870/4616/4893/5336/5579/6777",10,0.651827196449622
"WP4210","Tryptophan catabolism leading to NAD+ production","1/1022","11/4839",0.926665542554649,0.999930074063124,0.935607086842689,"23498",1,0.372869735553379
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms","6/1022","44/4839",0.926932208481225,0.999930074063124,0.935607086842689,"58/59/70/72/3690/7003",6,0.587287608785744
"WP2037","Prolactin Signaling Pathway","11/1022","73/4839",0.927200501963799,0.999930074063124,0.935607086842689,"1978/2316/2353/2534/2932/3717/4609/6196/8835/9021/6777",11,0.658961105261479
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection","7/1022","50/4839",0.927464167576974,0.999930074063124,0.935607086842689,"1019/2353/2534/2932/9020/1326/6237",7,0.605292702485966
"WP4018","Pathways in clear cell renal cell carcinoma","12/1022","79/4839",0.929965465976983,0.999930074063124,0.935607086842689,"32/47/2023/2194/5156/6472/8082/7043/84969/7167/7428/6935",12,0.664991872321561
"WP2507","Nanomaterial induced apoptosis","2/1022","19/4839",0.933260961114407,0.999930074063124,0.935607086842689,"596/637",2,0.438292964244521
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway","2/1022","19/4839",0.933260961114407,0.999930074063124,0.935607086842689,"32/8452",2,0.438292964244521
"WP2324","AGE/RAGE pathway","9/1022","63/4839",0.938090580026804,0.999930074063124,0.935607086842689,"1650/2308/3625/3717/4322/4846/5579/5590/6777",9,0.619118130964133
"WP534","Glycolysis and Gluconeogenesis","4/1022","33/4839",0.93995275510931,0.999930074063124,0.935607086842689,"2023/6515/6517/7167",4,0.513244360138202
"WP23","B Cell Receptor Signaling Pathway","14/1022","92/4839",0.941630174229579,0.999930074063124,0.935607086842689,"695/933/974/975/2308/2534/2932/3608/4208/4209/4609/8395/5336/5579",14,0.665776353276353
"WP3933","Kennedy pathway from Sphingolipids","1/1022","12/4839",0.942189116603769,0.999930074063124,0.935607086842689,"9791",1,0.338883447600392
"WP47","Hedgehog Signaling Pathway Netpath","1/1022","12/4839",0.942189116603769,0.999930074063124,0.935607086842689,"8643",1,0.338883447600392
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling","9/1022","64/4839",0.945010014311913,0.999930074063124,0.935607086842689,"47/2194/133522/5563/51422/6319/23411/6713/7528",9,0.607699901283317
"WP143","Fatty Acid Beta Oxidation","3/1022","27/4839",0.945300222572607,0.999930074063124,0.935607086842689,"34/38/7167",3,0.465284592737978
"WP4549","Fragile X Syndrome ","14/1022","93/4839",0.947247505263619,0.999930074063124,0.935607086842689,"627/26999/1915/1979/2534/2571/3708/4131/4204/4915/5909/6895/51256/9675",14,0.657172995780591
"WP2359","Parkin-Ubiquitin Proteasomal System pathway","8/1022","59/4839",0.950773104125175,0.999930074063124,0.935607086842689,"898/3306/5717/10213/5709/6622/10381/84617",8,0.582588854082067
"WP395","IL-4 Signaling Pathway","7/1022","53/4839",0.95079351505702,0.999930074063124,0.935607086842689,"332/2316/2353/3717/9021/6777/7297",7,0.565367316341829
"WP4159","GABA receptor Signaling","1/1022","13/4839",0.954429166910574,0.999930074063124,0.935607086842689,"2571",1,0.310561540972902
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling","2/1022","21/4839",0.954896495340778,0.999930074063124,0.935607086842689,"1066/2353",2,0.391950464396285
"WP4585","Cancer immunotherapy by PD-1 blockade","2/1022","21/4839",0.954896495340778,0.999930074063124,0.935607086842689,"4772/4776",2,0.391950464396285
"WP195","IL-1 signaling pathway","7/1022","55/4839",0.962362888607297,0.999930074063124,0.935607086842689,"6347/3316/11213/9020/4215/57161/5590",7,0.541522988505747
"WP4313","Ferroptosis","4/1022","36/4839",0.962835157966289,0.999930074063124,0.935607086842689,"84557/81631/55240/7037",4,0.464759332023576
"WP3845","Canonical and Non-canonical Notch signaling","2/1022","22/4839",0.963017752694939,0.999930074063124,0.935607086842689,"4237/6237",2,0.372254901960784
"WP453","Inflammatory Response Pathway","2/1022","22/4839",0.963017752694939,0.999930074063124,0.935607086842689,"3913/7133",2,0.372254901960784
"WP2637","Structural Pathway of Interleukin 1 (IL-1)","6/1022","49/4839",0.963456690090173,0.999930074063124,0.935607086842689,"2353/9020/4215/1326/4609/9252",6,0.518311664530306
"WP3","Phytochemical activity on NRF2 transcriptional activation","1/1022","14/4839",0.964079683159516,0.999930074063124,0.935607086842689,"2048",1,0.286596850749642
"WP4478","LTF danger signal response pathway","1/1022","14/4839",0.964079683159516,0.999930074063124,0.935607086842689,"3569",1,0.286596850749642
"WP3982","miRNA regulation of p53 pathway in prostate cancer","2/1022","23/4839",0.969724170558482,0.999930074063124,0.935607086842689,"637/11200",2,0.354435107376284
"WP4656","Joubert Syndrome","9/1022","69/4839",0.970349721382535,0.999930074063124,0.935607086842689,"57545/95681/2316/261734/5108/117177/79867/9094/23090",9,0.556317867719645
"WP61","Notch Signaling Pathway Netpath","7/1022","57/4839",0.971411720535189,0.999930074063124,0.935607086842689,"6868/2273/2932/3066/3717/4609/23385",7,0.519586206896552
"WP22","IL-9 Signaling Pathway","1/1022","15/4839",0.971688090166972,0.999930074063124,0.935607086842689,"6777",1,0.266055687701133
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)","1/1022","15/4839",0.971688090166972,0.999930074063124,0.935607086842689,"47",1,0.266055687701133
"WP481","Insulin Signaling","23/1022","150/4839",0.972563063883818,0.999930074063124,0.935607086842689,"1958/30846/1978/5167/2353/2308/2932/9020/4215/1326/5563/5579/5590/57381/6196/9252/6236/6517/9021/10580/6722/6812/6844",23,0.668936653188622
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway","6/1022","51/4839",0.972661216837911,0.999930074063124,0.935607086842689,"6387/8653/9636/54941/80143/7186",6,0.49501312335958
"WP2873","Aryl Hydrocarbon Receptor Pathway","3/1022","31/4839",0.973077357447465,0.999930074063124,0.935607086842689,"10486/3726/3727",3,0.398394784803028
"WP183","Proteasome Degradation","7/1022","58/4839",0.975146089269106,0.999930074063124,0.935607086842689,"5690/5691/5717/5709/6184/6185/7320",7,0.509263015551048
"WP100","Glutathione metabolism","1/1022","16/4839",0.97768617720042,0.999930074063124,0.935607086842689,"2878",1,0.248253346392426
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation","1/1022","16/4839",0.97768617720042,0.999930074063124,0.935607086842689,"34",1,0.248253346392426
"WP4494","Selective expression of chemokine receptors during T-cell polarization","1/1022","16/4839",0.97768617720042,0.999930074063124,0.935607086842689,"7043",1,0.248253346392426
"WP2533","Glycerophospholipid Biosynthetic Pathway","2/1022","25/4839",0.979795488915296,0.999930074063124,0.935607086842689,"5320/9791",2,0.323444160272805
"WP3851","TLR4 Signaling and Tolerance","2/1022","25/4839",0.979795488915296,0.999930074063124,0.935607086842689,"3569/11213",2,0.323444160272805
"WP581","EPO Receptor Signaling","2/1022","25/4839",0.979795488915296,0.999930074063124,0.935607086842689,"3717/6777",2,0.323444160272805
"WP244","Alpha 6 Beta 4 signaling pathway","3/1022","33/4839",0.981310074990616,0.999930074063124,0.935607086842689,"1978/3908/3913",3,0.371638861629048
"WP4263","Pancreatic adenocarcinoma pathway","11/1022","85/4839",0.981895728220499,0.999930074063124,0.935607086842689,"10000/9459/675/1019/1869/1870/4616/5881/5888/7043/7048",11,0.550338171999893
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition","1/1022","17/4839",0.98241450539888,0.999930074063124,0.935607086842689,"7431",1,0.232676297747307
"WP3874","Canonical and Non-Canonical TGF-B signaling","1/1022","17/4839",0.98241450539888,0.999930074063124,0.935607086842689,"7048",1,0.232676297747307
"WP405","Eukaryotic Transcription Initiation","4/1022","41/4839",0.983902757348175,0.999930074063124,0.935607086842689,"2960/3611/5436/5437",4,0.401423034036001
"WP1471","Target Of Rapamycin (TOR) Signaling","3/1022","34/4839",0.984463797563015,0.999930074063124,0.935607086842689,"1978/5563/51422",3,0.35955554148596
"WP313","Signaling of Hepatocyte Growth Factor Receptor","3/1022","34/4839",0.984463797563015,0.999930074063124,0.935607086842689,"2353/3082/5906",3,0.35955554148596
"WP4655","Cytosolic DNA-sensing pathway","6/1022","55/4839",0.98499866511702,0.999930074063124,0.935607086842689,"103/90865/3569/9636/5437/54941",6,0.454121806202796
"WP4722","Glycerolipids and Glycerophospholipids","1/1022","18/4839",0.986141667464899,0.999930074063124,0.935607086842689,"9791",1,0.218931843060437
"WP2583","T-Cell Receptor and Co-stimulatory Signaling","2/1022","27/4839",0.986584860633084,0.999930074063124,0.935607086842689,"2534/2932",2,0.297411764705882
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway","4/1022","43/4839",0.988609839372155,0.999930074063124,0.935607086842689,"23400/80347/84557/4204",4,0.38063573623495
"WP3945","TYROBP Causal Network","6/1022","57/4839",0.988988247391084,0.999930074063124,0.935607086842689,"54518/718/3071/5996/6696/7133",6,0.436081519221862
"WP3937","Microglia Pathogen Phagocytosis Pathway","3/1022","36/4839",0.989310274384808,0.999930074063124,0.935607086842689,"3071/5336/5881",3,0.337585868498528
"WP702","Metapathway biotransformation Phase I and II","11/1022","90/4839",0.990437699484362,0.999930074063124,0.935607086842689,"57404/1593/51302/2053/2878/2949/11185/7881/79829/55226/26151",11,0.514818014498742
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway","5/1022","52/4839",0.991808941236611,0.999930074063124,0.935607086842689,"2353/4286/4772/7185/7186",5,0.394359714638382
"WP4674","Head and Neck Squamous Cell Carcinoma","7/1022","66/4839",0.992314718762537,0.999930074063124,0.935607086842689,"10000/1017/1019/1978/4893/5563/7048",7,0.43927527761543
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway","2/1022","30/4839",0.992801390486254,0.999930074063124,0.935607086842689,"6347/3569",2,0.265336134453782
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway","15/1022","117/4839",0.993096492146131,0.999930074063124,0.935607086842689,"1978/2194/2308/2932/9020/4215/1326/5563/51422/6196/9252/6319/6567/6517/7067",15,0.542525848472458
"WP4217","Ebola Virus Pathway on Host","15/1022","118/4839",0.993885846002832,0.999930074063124,0.935607086842689,"6868/558/857/30835/10462/5610/2316/2318/2621/2934/3678/3690/388/9021/64601",15,0.537113988488349
"WP2272","Pathogenic Escherichia coli infection","4/1022","47/4839",0.994390806182559,0.999930074063124,0.935607086842689,"25/2534/10381/84617",4,0.344862246995934
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway","2/1022","32/4839",0.995269091959466,0.999930074063124,0.935607086842689,"22861/114548",2,0.247516339869281
"WP4329","miRNAs involvement in the immune response in sepsis","2/1022","32/4839",0.995269091959466,0.999930074063124,0.935607086842689,"3569/3663",2,0.247516339869281
"WP3869","Cannabinoid receptor signaling","1/1022","23/4839",0.995791481164406,0.999930074063124,0.935607086842689,"5577",1,0.168952007835455
"WP477","Cytoplasmic Ribosomal Proteins","9/1022","85/4839",0.996761791106334,0.999930074063124,0.935607086842689,"9801/6138/6122/6164/6133/6207/6228/6196/6203",9,0.437327895256404
"WP4532","Intraflagellar transport proteins binding to dynein","1/1022","25/4839",0.997388279639291,0.999930074063124,0.935607086842689,"89891",1,0.154791054521711
"WP710","DNA Damage Response (only ATM dependent)","11/1022","100/4839",0.997554537460786,0.999930074063124,0.935607086842689,"25/10000/596/894/8061/2932/4609/4893/5881/7472/7482",11,0.45575078629458
"WP4352","Ciliary landscape","27/1022","197/4839",0.997555018752146,0.999930074063124,0.935607086842689,"25904/51138/10238/9343/54512/3066/128239/25804/10982/55388/4171/4173/4174/4175/4176/84515/4436/4637/5048/10051/2040/79989/7431/89891/7465/10413/51646",27,0.582140112326338
"WP4205","MET in type 1 papillary renal cell carcinoma","4/1022","52/4839",0.99774780836319,0.999930074063124,0.935607086842689,"10000/3082/4893/5906",4,0.308529796987557
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway","8/1022","82/4839",0.998163678878075,0.999930074063124,0.935607086842689,"2353/2534/3569/3708/9020/1326/4772/7431",8,0.399061783677168
"WP4396","Nonalcoholic fatty liver disease","16/1022","135/4839",0.998441141628455,0.999930074063124,0.935607086842689,"10000/637/6347/84701/1346/2932/3569/3570/3953/5465/5563/51422/4092/9021/7186/7381",16,0.4942446163356
"WP1449","Regulation of toll-like receptor signaling pathway","12/1022","111/4839",0.998712123660994,0.999930074063124,0.935607086842689,"10000/695/8727/2353/3569/11213/3663/1326/57161/5347/6696/10771",12,0.446204620462046
"WP2526","PDGF Pathway","2/1022","39/4839",0.998937671665641,0.999930074063124,0.935607086842689,"2353/6722",2,0.200317965023847
"WP75","Toll-like Receptor Signaling Pathway","6/1022","78/4839",0.999677951800867,0.999930074063124,0.935607086842689,"10000/2353/3569/3663/1326/6696",6,0.307168635170604
"WP4536","Genes related to primary cilium development (based on CRISPR)","8/1022","95/4839",0.999779505063155,0.999930074063124,0.935607086842689,"57545/11116/51715/163786/79867/79989/79770/89891",8,0.338252964247659
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)","4/1022","70/4839",0.999930074063124,0.999930074063124,0.935607086842689,"1346/9481/291/7381",4,0.223313686967911
1 ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count odds_ratio
2 WP2446 Retinoblastoma Gene in Cancer 47/1022 86/4839 6.08288534347113e-12 3.01102824501821e-09 2.81733636960768e-09 25/54443/890/891/9133/898/9134/993/8318/8317/983/1017/1019/81620/1111/1786/1869/1870/2189/24137/4173/4175/4176/2956/4609/4998/5111/10733/5426/5427/5557/5591/5928/5947/5983/5984/5985/6119/6241/6502/10592/3925/7027/7153/7272/7298/7465 47 4.66971729125575
3 WP466 DNA Replication 26/1022 41/4839 4.88122298123165e-09 1.20810268785483e-06 1.13038847986417e-06 8318/990/8317/1017/81620/10926/55388/4171/4173/4174/4175/4176/4998/23594/5111/23649/5424/5426/5427/5557/5558/5982/5983/5984/5985/6119 26 6.61659973226238
4 WP2361 Gastric Cancer Network 1 16/1022 22/4839 2.8778815405389e-07 4.20813701870437e-05 3.93743814615614e-05 86/6790/1063/144455/1894/56992/9585/286826/4173/4605/57122/8607/64094/7153/22974/11065 16 10.1020543406229
5 WP179 Cell Cycle 48/1022 115/4839 3.40051476258939e-07 4.20813701870437e-05 3.93743814615614e-05 25/699/9184/890/891/9133/894/898/9134/991/993/995/8318/990/8317/983/1017/1019/1028/1111/11200/10926/1869/1870/9700/4616/2932/3066/10459/4171/4173/4174/4175/4176/4609/4998/23594/5111/9088/5347/5591/9232/5933/6502/7027/7043/7272/7465 48 2.75828250942413
6 WP45 G1 to S cell cycle control 30/1022 61/4839 9.28021377109086e-07 9.18741163337995e-05 8.59640854585259e-05 891/894/898/9134/993/8318/983/1017/1019/1028/90993/1869/1870/4171/4173/4174/4175/4176/4609/4998/23594/5111/23649/5426/5427/5557/5558/6119/7027/7465 30 3.69341831425598
7 WP289 Myometrial Relaxation and Contraction Pathways 46/1022 120/4839 9.77018041145599e-06 0.000806039883945119 0.000754189365094849 58/59/70/108/196883/111/115/408/467/489/800/817/1264/2353/2791/55970/54331/2788/2869/3488/3489/3569/3708/1902/23764/4846/5142/5144/11142/5331/5336/5577/5579/5590/10267/10266/10268/5996/8786/10287/5997/8490/8787/6262/6263/6546 46 2.38394439521489
8 WP4016 DNA IR-damage and cellular response via ATR 31/1022 75/4839 5.22036834352934e-05 0.00369154618578146 0.00345407830248558 672/675/83990/995/8318/983/1017/1111/11200/1196/63967/1869/9156/2175/2177/55215/2237/2305/4171/4436/79728/5111/5347/5591/5888/5883/55159/80010/55775/11073/7507 31 2.68239152371342
9 WP383 Striated Muscle Contraction Pathway 13/1022 23/4839 0.000209501159191158 0.0129628842249529 0.0121290144794881 58/59/70/1674/1756/10398/8736/7111/7139/7168/7169/7170/7431 13 4.90495540138751
10 WP536 Calcium Regulation in the Cardiac Cell 38/1022 107/4839 0.000369441897512897 0.0203193043632093 0.0190122146088508 108/196883/111/115/154/309/408/482/489/775/811/817/845/2701/57165/2775/2781/2791/55970/54331/2788/2869/3708/11142/5331/5350/5577/5579/5590/5996/8786/10287/5997/8490/8787/6262/6263/6546 38 2.09767880287499
11 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 7/1022 9/4839 0.000442625689689891 0.0219099716396496 0.0205005582593213 817/894/9314/4208/4209/93649/6722 7 13.1551724137931
12 WP531 DNA Mismatch Repair 11/1022 21/4839 0.00152210454302198 0.0629714363335005 0.0589206421833923 9156/3978/4436/2956/5111/5424/5982/5983/5984/5985/6119 11 4.14213649851632
13 WP2406 Cardiac Progenitor Differentiation 14/1022 30/4839 0.00152658027475153 0.0629714363335005 0.0589206421833923 70/22943/2247/2932/3479/3624/3815/4208/4684/5156/4920/64321/6910/7139 14 3.29947916666667
14 WP1530 miRNA Regulation of DNA Damage Response 24/1022 64/4839 0.00186690102319929 0.0710858466525883 0.0665130728913107 25/637/672/891/9133/894/898/9134/993/995/983/1017/1019/1020/1111/11200/1869/2177/4616/4176/4609/5591/5888/5883 24 2.27074148296593
15 WP35 G Protein Signaling Pathways 27/1022 76/4839 0.00250847820080499 0.0790149987243626 0.0739321625491112 108/196883/111/115/9590/11214/9472/9465/9630/2774/2775/2781/2791/55970/2788/3708/4893/5136/5142/5144/27115/5331/5533/5577/5579/5590/6237 27 2.08667828940621
16 WP707 DNA Damage Response 23/1022 62/4839 0.00271330802302758 0.0790149987243626 0.0739321625491112 25/637/672/891/9133/894/898/9134/993/995/983/1017/1019/1020/1111/11200/1869/2177/4616/4609/5591/5888/5883 23 2.2302815636149
17 WP1602 Nicotine Activity on Dopaminergic Neurons 7/1022 11/4839 0.00271364642083669 0.0790149987243626 0.0739321625491112 108/1020/1138/54331/3777/84152/6571 7 6.57413793103448
18 WP2023 Cell Differentiation - Index expanded 7/1022 11/4839 0.00271364642083669 0.0790149987243626 0.0739321625491112 2146/10014/3398/9314/4208/4209/6722 7 6.57413793103448
19 WP2848 Differentiation Pathway 12/1022 26/4839 0.0036947121263992 0.0968690978699419 0.0906377523929281 22943/2247/3082/3479/3569/3570/3624/3815/4907/7043/7472/7482 12 3.22743988684583
20 WP558 Complement and Coagulation Cascades 16/1022 39/4839 0.00371820779702807 0.0968690978699419 0.0906377523929281 623/715/716/718/730/1675/3075/1191/2159/2161/2157/5648/5627/710/7035/7450 16 2.62356297000605
21 WP2516 ATM Signaling Pathway 15/1022 37/4839 0.00561025279060555 0.138853756567487 0.129921643571918 25/637/672/835/891/898/993/995/983/1017/1111/11200/2177/5888/5883 15 2.5695134061569
22 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition 8/1022 15/4839 0.00595545166757851 0.140378503592922 0.131348307455366 699/701/9184/991/1062/9700/4085/9232 8 4.29416737109045
23 WP4222 Phosphodiesterases in neuronal function 13/1022 31/4839 0.00694925428195734 0.149785380106981 0.140150063257994 108/196883/111/115/2906/5136/5138/5140/5142/5144/8654/27115/84152 13 2.71924898138971
24 WP236 Adipogenesis 33/1022 104/4839 0.00695972473224355 0.149785380106981 0.140150063257994 1052/1675/55847/1869/1879/1959/2308/2487/4616/3479/3569/3572/28999/1316/3977/4154/4208/4209/4692/7025/2908/5465/10891/5740/5914/5933/6095/6319/6517/9021/6773/6777/25937 33 1.76046369216309
25 WP2806 Human Complement System 22/1022 63/4839 0.00765136578770975 0.151658530005302 0.141902718133616 715/716/718/730/811/966/22918/1675/3075/5199/1634/2159/2161/2162/3690/5648/5627/5806/6401/6403/710/6696 22 2.02614634146341
26 WP3996 Ethanol effects on histone modifications 12/1022 28/4839 0.00765952171743951 0.151658530005302 0.141902718133616 125/126/191/217/3066/9759/10014/10013/8850/4524/6573/7298 12 2.82252475247525
27 WP247 Small Ligand GPCRs 6/1022 10/4839 0.00837134097206408 0.153474584487841 0.14360195039798 1902/5733/5734/5737/1901/9294 6 5.62942913385827
28 WP4545 Oxysterols derived from cholesterol 6/1022 10/4839 0.00837134097206408 0.153474584487841 0.14360195039798 9023/1593/1717/2053/2099/1880 6 5.62942913385827
29 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma 7/1022 13/4839 0.00947004961583731 0.167416948565695 0.156647437254452 3590/3569/3570/3572/3717/6659/6935 7 4.38045977011494
30 WP2363 Gastric Cancer Network 2 12/1022 29/4839 0.0106076900909422 0.181062296379876 0.169415014156609 29028/27101/63922/79075/55215/84823/4609/5983/5984/7153/11065/29089 12 2.65579499126383
31 WP1971 Integrated Cancer Pathway 16/1022 43/4839 0.0111649064981956 0.184220957220227 0.172370486287932 596/641/672/993/983/1017/1019/1111/11200/1869/4312/4436/2956/4609/5347/5451 16 2.23253074147706
32 WP474 Endochondral Ossification 19/1022 54/4839 0.0116567995879756 0.18613276761445 0.17415931472697 9510/9507/11096/1028/5167/2247/2260/2487/2690/9759/3479/4208/4256/4322/5745/6696/6777/7067/7078 19 2.04694487964677
33 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 31/1022 100/4839 0.012513191903912 0.193563437263639 0.181111988082937 34/627/1390/1958/2305/23171/7184/3569/3570/3757/4150/4204/4208/4602/2908/4915/5354/10891/133522/5577/6095/6262/6330/291/6640/6869/6929/11076/7259/6844/7434 31 1.69917664780123
34 WP4149 White fat cell differentiation 12/1022 30/4839 0.0143601520308822 0.214413838417165 0.20062113536109 1052/1879/1959/2308/28999/10365/9314/2908/5914/6095/6777/23090 12 2.50759075907591
35 WP4589 Major receptors targeted by epinephrine and norepinephrine 6/1022 11/4839 0.0151605744335369 0.214413838417165 0.20062113536109 108/196883/111/115/150/154 6 4.50236220472441
36 WP554 ACE Inhibitor Pathway 6/1022 11/4839 0.0151605744335369 0.214413838417165 0.20062113536109 185/623/624/1511/4846/4306 6 4.50236220472441
37 WP2431 Spinal Cord Injury 28/1022 90/4839 0.0162686915442285 0.221975388746869 0.207696270172509 358/627/7832/6347/983/1017/1019/1464/2920/1869/1958/2353/3569/4321/4609/4804/3164/9423/5320/56963/388/65078/6403/9353/6586/6869/7431/7538 28 1.70604270786006
38 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM 18/1022 52/4839 0.0165920997649174 0.221975388746869 0.207696270172509 25/86/637/641/672/675/995/1020/1111/11200/1869/9156/2177/5111/5591/5888/5883/10413 18 1.99478556362784
39 WP2029 Cell Differentiation - Index 4/1022 6/4839 0.0205766471129607 0.261165136433732 0.244365039937995 10014/4208/4209/6722 4 7.4950884086444
40 WP3944 Serotonin and anxiety-related events 4/1022 6/4839 0.0205766471129607 0.261165136433732 0.244365039937995 2353/2906/84812/5579 4 7.4950884086444
41 WP3893 Development and heterogeneity of the ILC family 8/1022 18/4839 0.0221682040659433 0.274331525316048 0.256684468131975 374/3398/90865/3569/6095/9760/85480/7704 8 3.00355029585799
42 WP516 Hypertrophy Model 7/1022 15/4839 0.023921397351209 0.281930754496392 0.26379485800832 467/1978/1839/3727/8013/9948/6935 7 3.28362068965517
43 WP545 Complement Activation 7/1022 15/4839 0.023921397351209 0.281930754496392 0.26379485800832 715/716/718/730/1675/5199/5648 7 3.28362068965517
44 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) 6/1022 12/4839 0.0249881820525124 0.283655270848162 0.265408440559683 374/2099/8061/4609/5241/7431 6 3.7509842519685
45 WP428 Wnt Signaling 28/1022 93/4839 0.0252138018531699 0.283655270848162 0.265408440559683 817/894/1457/23500/22943/8061/2535/8324/2932/4609/4772/4776/85407/51701/5331/5332/5532/5533/166336/5579/4919/4920/5176/6422/64321/81839/7472/7482 28 1.62600216684724
46 WP4172 PI3K-Akt Signaling Pathway 66/1022 252/4839 0.0279094709530498 0.306261336676163 0.286560315018632 10000/284/596/627/672/894/898/9134/1017/1019/1286/1288/1291/1292/90993/9586/1440/1944/1945/1975/1978/2256/2258/2247/2252/2260/2690/2791/55970/54331/2788/2932/3082/7184/3479/3563/3569/3570/3678/3679/8516/3680/3690/3717/3815/3908/3913/10319/1902/4602/4609/4804/4846/4893/4915/80310/5156/5516/5521/5525/5563/5649/6696/7010/7148/7450 66 1.34771899041706
47 WP170 Nuclear Receptors 11/1022 29/4839 0.028460649468896 0.306261336676163 0.286560315018632 2099/7025/2908/3164/4929/5241/5465/5914/4919/6095/7067 11 2.29635124738982
48 WP3297 EV release from cardiac cells and their functional effects 3/1022 4/4839 0.0316543966692141 0.333381411728957 0.31193582383996 6387/10365/4602 3 11.234543670265
49 WP2858 Ectoderm Differentiation 32/1022 112/4839 0.0363507203093282 0.369978106127767 0.34617834491487 79658/55843/23229/91653/10486/6347/5010/1756/2534/8322/2627/10013/3853/9079/4204/4609/4772/51701/51422/56963/114822/4920/6386/6622/8835/114815/10253/6781/6929/7226/8848/7704 32 1.50989898989899
50 WP4752 Base Excision Repair 11/1022 30/4839 0.0366240953540618 0.369978106127767 0.34617834491487 2237/3978/4595/10038/5111/11284/5424/5426/5427/23583/7374 11 2.17491800718413
51 WP3591 Sleep regulation 6/1022 13/4839 0.0382894384268054 0.379065440425373 0.354681113848302 191/1471/2353/3569/8863/5730 6 3.21428571428571
52 WP1992 Genes targeted by miRNAs in adipocytes 5/1022 10/4839 0.0406085173589397 0.38656184793606 0.361695296314442 2078/9464/9759/3479/6722 5 3.74827925270403
53 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) 5/1022 10/4839 0.0406085173589397 0.38656184793606 0.361695296314442 1116/1869/3572/4609/9021 5 3.74827925270403
54 WP1984 Integrated Breast Cancer Pathway 39/1022 143/4839 0.0451540264348633 0.421721567646365 0.394593279669113 25/6790/596/637/641/672/675/993/1017/1019/1111/11200/55526/1869/26284/2099/27145/8061/2308/4312/4436/2956/4609/79902/4953/5347/1263/5888/8438/5906/6237/23411/4092/6597/7035/7048/27005/7465/7517 39 1.41645473041709
55 WP34 Ovarian Infertility Genes 7/1022 17/4839 0.0488930677721469 0.440037609949322 0.411731097028606 894/1019/1958/2701/5241/6609/7784 7 2.62551724137931
56 WP4300 Extracellular vesicles in the crosstalk of cardiac cells 7/1022 17/4839 0.0488930677721469 0.440037609949322 0.411731097028606 332/975/3479/3569/10611/8470/6696 7 2.62551724137931
57 WP2849 Hematopoietic Stem Cell Differentiation 14/1022 43/4839 0.0536575816417183 0.467920123508186 0.43781999860415 863/947/1440/2313/2353/2354/3569/3663/3690/3757/4602/3071/399/7148 14 1.81417624521073
58 WP1601 Fluoropyrimidine Activity 10/1022 28/4839 0.0538817111918517 0.467920123508186 0.43781999860415 1066/8836/4524/5471/6241/23583/7083/7298/7371/7517 10 2.08552920509442
59 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 5/1022 11/4839 0.0618151364634419 0.524734603786845 0.490979746233305 1634/22943/2308/6422/4093 5 3.12274664044576
60 WP241 One Carbon Metabolism 9/1022 25/4839 0.062831257423353 0.524734603786845 0.490979746233305 191/1786/1788/1789/2618/25902/4524/6472/7298 9 2.11062438302073
61 WP2895 Differentiation of white and brown adipocyte 7/1022 18/4839 0.0658997992215493 0.524734603786845 0.490979746233305 253738/27129/10891/133522/63976/4093/23090 7 2.38620689655172
62 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 17/1022 56/4839 0.0661533109186531 0.524734603786845 0.490979746233305 775/781/783/785/1674/1756/3678/3679/8516/3680/3690/3908/6262/6442/6443/6444/6546 17 1.63862737594081
63 WP206 Fatty Acid Omega Oxidation 3/1022 5/4839 0.0667844041183257 0.524734603786845 0.490979746233305 125/126/217 3 5.61579980372915
64 WP3299 let-7 inhibition of ES cell reprogramming 3/1022 5/4839 0.0667844041183257 0.524734603786845 0.490979746233305 1958/9314/4609 3 5.61579980372915
65 WP98 Prostaglandin Synthesis and Regulation 12/1022 37/4839 0.0728698633344591 0.559196388737501 0.523224691216376 309/1909/1910/4286/10891/133522/5730/5733/5734/5737/5740/5742 12 1.80213861386139
66 WP4698 Vitamin D-sensitive calcium signaling in depression 8/1022 22/4839 0.0734298288241164 0.559196388737501 0.523224691216376 493/596/775/1593/2906/3708/23028/6546 8 2.14313891236968
67 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 20/1022 69/4839 0.0752279353205046 0.564209514903784 0.527915335582488 894/1457/22943/2146/8061/2535/8324/2932/9314/4609/85407/51701/4919/4920/5176/6422/64321/83595/7472/7482 20 1.53488940486374
68 WP3998 Prader-Willi and Angelman Syndrome 10/1022 30/4839 0.0825797783657116 0.610104332701899 0.570857855159672 627/894/990/1019/1869/9638/4487/4692/5108/5590 10 1.87598814229249
69 WP4224 Purine metabolism and related disorders 7/1022 19/4839 0.0860390711246063 0.623135020434443 0.583050311517608 316/1716/2618/3251/3704/10606/5471 7 2.1867816091954
70 WP3624 Lung fibrosis 13/1022 42/4839 0.087955807542379 0.623135020434443 0.583050311517608 6347/1440/2920/2006/2247/2252/3082/3479/3569/4204/5806/4092/6696 13 1.68292266156317
71 WP4760 PKC-gamma calcium signaling pathway in ataxia 5/1022 12/4839 0.0881201038998203 0.623135020434443 0.583050311517608 9630/3708/5331/5332/6263 5 2.67593763168984
72 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway 60/1022 243/4839 0.0951492832930012 0.663364721549797 0.620692137122617 10000/284/1301/1286/1288/1292/90993/9586/1440/1944/1945/1975/1978/2256/2258/2247/2252/2260/2308/2690/2791/55970/54331/2788/2932/3082/64344/7184/3479/3563/3570/3678/3679/8516/3680/3690/3717/3815/3908/3913/10319/1902/4804/4846/4893/80310/5156/5210/10891/5516/5521/5525/5563/5649/6515/6517/6696/7010/7148/7450 60 1.23853992706452
73 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 4/1022 9/4839 0.100966138374052 0.685679647373976 0.641571599882083 3708/6262/6263/7220 4 2.99567779960707
74 WP497 Urea cycle and metabolism of amino groups 6/1022 16/4839 0.101120432845051 0.685679647373976 0.641571599882083 5832/1152/2593/162417/4953/5831 6 2.24822834645669
75 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer 21/1022 76/4839 0.106066145727212 0.70949651533743 0.663856388619817 467/894/1457/22943/2146/8061/2535/8324/2932/4609/85407/51701/4919/4920/8607/5176/6422/64321/6929/7472/7482 21 1.43496503496503
76 WP2338 miRNA Biogenesis 3/1022 6/4839 0.112992161123691 0.735935786266143 0.688594887734403 5901/6895/57510 3 3.74288518155054
77 WP4571 Urea cycle and related diseases 3/1022 6/4839 0.112992161123691 0.735935786266143 0.688594887734403 162417/10165/10166 3 3.74288518155054
78 WP1495 Glycine Metabolism 2/1022 3/4839 0.114915958441986 0.738745447127052 0.691223810177358 4524/6472 2 7.48235294117647
79 WP2355 Corticotropin-releasing hormone signaling pathway 20/1022 73/4839 0.120714965545451 0.766075742884595 0.716796016734124 408/596/8912/2353/2354/8061/2775/2781/2932/3726/3727/4846/3164/4929/5336/5563/5579/10411/9095/6925 20 1.41754227394268
80 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 6/1022 17/4839 0.12960808652118 0.812101301620054 0.759860867012917 3690/3708/4026/8076/4638/7414 6 2.04330708661417
81 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 7/1022 21/4839 0.135477853961833 0.83826922138884 0.784345470305348 22943/2932/4609/5914/862/6929/7704 7 1.87339901477833
82 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) 8/1022 25/4839 0.138618514440201 0.84711314380123 0.792620485428051 857/2099/3717/4609/2908/5241/7170/7528 8 1.76354565494837
83 WP2855 Dopaminergic Neurogenesis 4/1022 10/4839 0.141204552384128 0.852393334513942 0.797561014749887 1028/4487/4929/6571 4 2.49574328749181
84 WP2877 Vitamin D Receptor Pathway 30/1022 118/4839 0.148165697304679 0.883638797178506 0.826796535371702 5243/11096/154/623/768/898/4345/1017/78989/1474/2308/50486/29923/3400/3488/3663/3726/9365/9314/4609/5734/6304/7869/6422/6517/6546/6696/79689/7078/7168 30 1.28150201612903
85 WP1545 miRNAs involved in DNA damage response 5/1022 14/4839 0.1547702251525 0.912038826791517 0.853369662494987 25/898/993/1869/4609 5 2.08019228668196
86 WP1541 Energy Metabolism 12/1022 42/4839 0.15854563148268 0.912159802926657 0.853482856539562 2308/2932/4208/4209/5465/10891/133522/5532/5533/5563/51422/23411 12 1.49980198019802
87 WP2038 Regulation of Microtubule Cytoskeleton 12/1022 42/4839 0.15854563148268 0.912159802926657 0.853482856539562 25/9212/983/1073/1808/2048/2932/11004/3984/4131/3925/11076 12 1.49980198019802
88 WP117 GPCRs, Other 7/1022 22/4839 0.1644335990261 0.912159802926657 0.853482856539562 154/1951/1909/1880/59352/5737/1901 7 1.74804597701149
89 WP2879 Farnesoid X Receptor Pathway 3/1022 7/4839 0.167689983972375 0.912159802926657 0.853482856539562 5244/2289/10891 3 2.80642787046124
90 WP322 Osteoblast Signaling 3/1022 7/4839 0.167689983972375 0.912159802926657 0.853482856539562 3690/5156/5745 3 2.80642787046124
91 WP3407 FTO Obesity Variant Mechanism 3/1022 7/4839 0.167689983972375 0.912159802926657 0.853482856539562 84159/10891/63976 3 2.80642787046124
92 WP3947 Serotonin and anxiety 3/1022 7/4839 0.167689983972375 0.912159802926657 0.853482856539562 2353/84812/5579 3 2.80642787046124
93 WP3594 Circadian rhythm related genes 34/1022 138/4839 0.177587188667422 0.920698826812516 0.861472586491243 191/1019/1390/1408/1471/1958/1960/2146/2932/3066/3398/3400/3569/3727/3778/7071/687/56339/4804/4841/5187/8864/8863/5465/10891/5563/5591/5730/6095/23411/8914/7153/7298/9099 34 1.22860868888197
94 WP4321 Thermogenesis 23/1022 90/4839 0.180110321104423 0.920698826812516 0.861472586491243 86/108/196883/111/115/353500/656/90993/9586/2260/23028/11343/4881/4893/10891/63976/5563/51422/5592/6196/6597/6598/6602 23 1.28860203487069
95 WP4259 Disorders of Folate Metabolism and Transport 4/1022 11/4839 0.186569932910234 0.920698826812516 0.861472586491243 2618/4524/6472/7298 4 2.13864720740949
96 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) 15/1022 56/4839 0.187328788615833 0.920698826812516 0.861472586491243 6868/4345/947/22943/1959/2353/2354/3479/3488/4487/4772/2908/6422/6929/6925 15 1.37186039189091
97 WP2197 Endothelin Pathways 7/1022 23/4839 0.195858426981202 0.920698826812516 0.861472586491243 790/1264/1909/1910/4638/4846/10267 7 1.63836206896552
98 WP3599 Transcription factor regulation in adipogenesis 6/1022 19/4839 0.196272918961637 0.920698826812516 0.861472586491243 1052/2308/3569/2908/10891/6517 6 1.72804360993337
99 WP4288 MTHFR deficiency 6/1022 19/4839 0.196272918961637 0.920698826812516 0.861472586491243 501/1786/1788/1789/2906/4524 6 1.72804360993337
100 WP1995 Effects of Nitric Oxide 2/1022 4/4839 0.198177520214758 0.920698826812516 0.861472586491243 316/4846 2 3.74019607843137
101 WP2542 Sulindac Metabolic Pathway 2/1022 4/4839 0.198177520214758 0.920698826812516 0.861472586491243 4482/253827 2 3.74019607843137
102 WP334 GPCRs, Class B Secretin-like 2/1022 4/4839 0.198177520214758 0.920698826812516 0.861472586491243 5745/7434 2 3.74019607843137
103 WP4720 Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway 2/1022 4/4839 0.198177520214758 0.920698826812516 0.861472586491243 2053/5465 2 3.74019607843137
104 WP176 Folate Metabolism 12/1022 44/4839 0.20300016766834 0.920698826812516 0.861472586491243 191/6347/80308/2350/2618/2878/3569/4524/12/6472/6573/6649 12 1.40532178217822
105 WP410 Exercise-induced Circadian Regulation 12/1022 44/4839 0.20300016766834 0.920698826812516 0.861472586491243 11335/7122/1408/50486/2674/687/5187/8864/5516/5813/11030/10381 12 1.40532178217822
106 WP1438 Influenza A virus infection 1/1022 1/4839 0.211200661293655 0.920698826812516 0.861472586491243 596 1 Inf
107 WP1600 Nicotine Metabolism 1/1022 1/4839 0.211200661293655 0.920698826812516 0.861472586491243 316 1 Inf
108 WP1603 Nicotine Activity on Chromaffin Cells 1/1022 1/4839 0.211200661293655 0.920698826812516 0.861472586491243 775 1 Inf
109 WP4400 FABP4 in ovarian cancer 1/1022 1/4839 0.211200661293655 0.920698826812516 0.861472586491243 2167 1 Inf
110 WP2525 Trans-sulfuration and one carbon metabolism 8/1022 28/4839 0.224525950160984 0.920698826812516 0.861472586491243 191/1786/1788/1789/25902/4524/6472/7298 8 1.49783037475345
111 WP1455 Serotonin Transporter Activity 3/1022 8/4839 0.228117947120316 0.920698826812516 0.861472586491243 3690/5516/7041 3 2.24455348380765
112 WP3875 ATR Signaling 3/1022 8/4839 0.228117947120316 0.920698826812516 0.861472586491243 1111/5883/11073 3 2.24455348380765
113 WP4191 Caloric restriction and aging 3/1022 8/4839 0.228117947120316 0.920698826812516 0.861472586491243 3479/10891/23411 3 2.24455348380765
114 WP4583 Biomarkers for urea cycle disorders 3/1022 8/4839 0.228117947120316 0.920698826812516 0.861472586491243 2159/2593/162417 3 2.24455348380765
115 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 15/1022 58/4839 0.228867396275626 0.920698826812516 0.861472586491243 375790/1028/1286/22943/2534/3611/3690/3913/4288/55742/5111/11346/7094/7414/7431 15 1.30736010715688
116 WP4657 22q11.2 Deletion Syndrome 15/1022 58/4839 0.228867396275626 0.920698826812516 0.861472586491243 59/70/8318/7122/2260/9464/5308/5902/65078/6576/6517/6722/27037/7450/7625 15 1.30736010715688
117 WP1528 Physiological and Pathological Hypertrophy of the Heart 7/1022 24/4839 0.229413888363834 0.920698826812516 0.861472586491243 817/2353/3572/3977/4776/5532/5579 7 1.54158215010142
118 WP3640 Imatinib and Chronic Myeloid Leukemia 6/1022 20/4839 0.233557704720861 0.920698826812516 0.861472586491243 5243/25/3815/4609/5156/6502 6 1.60419010123735
119 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 6/1022 20/4839 0.233557704720861 0.920698826812516 0.861472586491243 596/83596/599/637/2932/4609 6 1.60419010123735
120 WP4538 Regulatory circuits of the STAT3 signaling pathway 17/1022 67/4839 0.235097418060392 0.920698826812516 0.861472586491243 185/2690/3590/58985/3563/3570/3572/3717/3977/225689/5156/5579/5789/80854/9021/3925/7297 17 1.27440796019901
121 WP4658 Small cell lung cancer 22/1022 89/4839 0.235584492112176 0.920698826812516 0.861472586491243 10000/596/637/330/898/9134/1017/1019/1028/1163/1164/1286/1288/1869/1870/4616/3908/3913/10319/4609/7185/7186 22 1.23134328358209
122 WP186 Homologous recombination 4/1022 12/4839 0.235794847415441 0.920698826812516 0.861472586491243 675/5424/5888/25788 4 1.87082514734774
123 WP272 Blood Clotting Cascade 4/1022 12/4839 0.235794847415441 0.920698826812516 0.861472586491243 2159/2161/2157/7450 4 1.87082514734774
124 WP4584 Biomarkers for pyrimidine metabolism disorders 4/1022 12/4839 0.235794847415441 0.920698826812516 0.861472586491243 1152/80324/6241/7298 4 1.87082514734774
125 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 5/1022 16/4839 0.236219699000383 0.920698826812516 0.861472586491243 2194/5465/10891/6319/23411 5 1.70108161258604
126 WP2878 PPAR Alpha Pathway 5/1022 16/4839 0.236219699000383 0.920698826812516 0.861472586491243 34/983/1019/4609/5465 5 1.70108161258604
127 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS 5/1022 16/4839 0.236219699000383 0.920698826812516 0.861472586491243 2920/2247/3479/5354/6663 5 1.70108161258604
128 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 5/1022 16/4839 0.236219699000383 0.920698826812516 0.861472586491243 1958/2908/5906/9252/6722 5 1.70108161258604
129 WP2064 Neural Crest Differentiation 16/1022 64/4839 0.264602321898724 0.999930074063124 0.935607086842689 2247/2260/2932/3066/9759/10014/10013/4286/4359/4487/4602/4609/5376/388/6663/6925 16 1.24884029158383
130 WP2374 Oncostatin M Signaling Pathway 16/1022 64/4839 0.264602321898724 0.999930074063124 0.935607086842689 6347/1017/1958/2353/3572/3717/3726/3727/3977/4312/4322/5579/9021/6777/7078/7297 16 1.24884029158383
131 WP3584 MECP2 and Associated Rett Syndrome 13/1022 51/4839 0.268668191587185 0.999930074063124 0.935607086842689 627/1052/1465/1869/2146/2247/2289/2571/2593/114787/3479/4204/4208 13 1.28128423139116
132 WP24 Peptide GPCRs 6/1022 21/4839 0.272789645024472 0.999930074063124 0.935607086842689 185/623/624/1909/1910/6869 6 1.49685039370079
133 WP382 MAPK Signaling Pathway 45/1022 195/4839 0.272925856991294 0.999930074063124 0.935607086842689 10000/408/627/775/8912/781/783/785/1843/1850/2256/2258/2247/2252/2260/2316/2318/2353/55970/3306/3727/120892/9020/1326/23542/4208/4609/4772/51701/3164/4893/4915/8605/5532/5533/5881/5906/10235/9252/6237/6722/3925/7043/7048/7186 45 1.12599795291709
134 WP727 Monoamine Transport 5/1022 17/4839 0.28064120420005 0.999930074063124 0.935607086842689 995/114907/3690/5516/7041 5 1.55891510980007
135 WP136 Phase I biotransformations, non P450 2/1022 5/4839 0.285772930945712 0.999930074063124 0.935607086842689 1066/2098 2 2.49281045751634
136 WP2276 Glial Cell Differentiation 2/1022 5/4839 0.285772930945712 0.999930074063124 0.935607086842689 5354/11076 2 2.49281045751634
137 WP2874 Liver X Receptor Pathway 2/1022 5/4839 0.285772930945712 0.999930074063124 0.935607086842689 2194/6319 2 2.49281045751634
138 WP58 Monoamine GPCRs 2/1022 5/4839 0.285772930945712 0.999930074063124 0.935607086842689 150/154 2 2.49281045751634
139 WP3958 GPR40 Pathway 4/1022 13/4839 0.287586215235435 0.999930074063124 0.935607086842689 5310/5331/5336/5334 4 1.66251910063305
140 WP4211 Transcriptional cascade regulating adipogenesis 4/1022 13/4839 0.287586215235435 0.999930074063124 0.935607086842689 1052/1959/28999/10365 4 1.66251910063305
141 WP4493 Cells and Molecules involved in local acute inflammatory response 4/1022 13/4839 0.287586215235435 0.999930074063124 0.935607086842689 718/730/3569/6403 4 1.66251910063305
142 WP53 ID signaling pathway 4/1022 13/4839 0.287586215235435 0.999930074063124 0.935607086842689 898/1017/3398/5933 4 1.66251910063305
143 WP4753 Nucleotide Excision Repair 11/1022 43/4839 0.288668808814214 0.999930074063124 0.935607086842689 3978/5111/5424/5426/5427/5982/5983/5984/5985/6119/7507 11 1.28693743818002
144 WP1591 Heart Development 8/1022 30/4839 0.290225800257854 0.999930074063124 0.935607086842689 2627/9464/4208/4772/4776/5308/6722/6910 8 1.36094674556213
145 WP4539 Synaptic signaling pathways associated with autism spectrum disorder 10/1022 39/4839 0.299745088293227 0.999930074063124 0.935607086842689 10000/627/775/1978/2906/2932/4893/4915/5563/51422 10 1.29071827722502
146 WP4022 Pyrimidine metabolism 19/1022 79/4839 0.300328097507354 0.999930074063124 0.935607086842689 790/1841/5167/953/4830/87178/23649/5424/5426/5427/5436/5437/5557/5558/6241/7083/7298/7371/54963 19 1.1861581920904
147 WP3298 Melatonin metabolism and effects 7/1022 26/4839 0.301387118348426 0.999930074063124 0.935607086842689 1408/2308/2932/5187/8864/8863/23411 7 1.37858439201452
148 WP3965 Lipid Metabolism Pathway 7/1022 26/4839 0.301387118348426 0.999930074063124 0.935607086842689 47/10000/2194/29923/5563/51422/5577 7 1.37858439201452
149 WP4204 Tumor suppressor activity of SMARCB1 7/1022 26/4839 0.301387118348426 0.999930074063124 0.935607086842689 86/1019/2146/5928/6597/6598/6602 7 1.37858439201452
150 WP129 Matrix Metalloproteinases 6/1022 22/4839 0.313423162273861 0.999930074063124 0.935607086842689 4312/4320/4321/4322/7078/7079 6 1.4029281496063
151 WP4483 Relationship between inflammation, COX-2 and EGFR 6/1022 22/4839 0.313423162273861 0.999930074063124 0.935607086842689 10000/2099/4312/4893/5733/5734 6 1.4029281496063
152 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 15/1022 62/4839 0.321510953260271 0.999930074063124 0.935607086842689 108/898/1017/1019/1869/1958/2353/2775/54331/3717/4609/5144/5906/5909/8458 15 1.19482769549325
153 WP2267 Synaptic Vesicle Pathway 8/1022 31/4839 0.324706678082801 0.999930074063124 0.935607086842689 477/6571/6581/291/81539/2054/6812/6844 8 1.3014321241746
154 WP4148 Splicing factor NOVA regulated synaptic proteins 8/1022 31/4839 0.324706678082801 0.999930074063124 0.935607086842689 375790/57863/2037/3778/5332/5590/5909/2054 8 1.3014321241746
155 WP2882 Nuclear Receptors Meta-Pathway 50/1022 222/4839 0.325747953159628 0.999930074063124 0.935607086842689 5243/5244/34/11214/330/10486/6347/983/1019/1028/1066/80315/1958/2042/2099/2194/2258/2289/2308/4616/2878/2949/1839/3082/3726/3727/8850/23764/4609/89795/2908/5142/5166/5465/10891/5997/6319/6515/6517/201266/55630/8884/6533/6649/10252/5552/2040/7048/7049/1831 50 1.09011627906977
156 WP167 Eicosanoid Synthesis 5/1022 18/4839 0.326479271134302 0.999930074063124 0.935607086842689 4056/5320/5730/5740/5742 5 1.43862037667347
157 WP4286 Genotoxicity pathway 12/1022 49/4839 0.332768133185829 0.999930074063124 0.935607086842689 59/7832/1052/1062/8161/144455/79733/3398/3708/1263/5734/29950 12 1.21380786727321
158 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 7/1022 27/4839 0.338998676265558 0.999930074063124 0.935607086842689 3066/9759/10014/4772/4776/5532/5533 7 1.30931034482759
159 WP3935 Leptin Insulin Overlap 4/1022 14/4839 0.340712611268609 0.999930074063124 0.935607086842689 3717/3953/8835/9021 4 1.4958742632613
160 WP306 Focal Adhesion 39/1022 173/4839 0.349496348233832 0.999930074063124 0.935607086842689 10000/596/330/857/894/1286/1288/1292/2316/2318/2534/2932/3082/3479/3611/3678/3679/8516/3680/3690/3908/3913/10319/10398/4638/55742/80310/5156/4660/5579/5881/5906/5649/6696/7094/7148/7414/7450/7791 39 1.09045565661013
161 WP2881 Estrogen Receptor Pathway 3/1022 10/4839 0.356189265397442 0.999930074063124 0.935607086842689 2099/5166/5465 3 1.60241132763213
162 WP4535 Envelope proteins and their potential roles in EDMD physiopathology 10/1022 41/4839 0.361187936985075 0.999930074063124 0.935607086842689 108/196883/111/115/1072/4893/6722/23345/7043/7112 10 1.20680861915084
163 WP2113 Type III interferon signaling 2/1022 6/4839 0.372163315856723 0.999930074063124 0.935607086842689 6773/7297 2 1.86911764705882
164 WP3595 mir-124 predicted interactions with cell cycle and differentiation 2/1022 6/4839 0.372163315856723 0.999930074063124 0.935607086842689 5725/51804 2 1.86911764705882
165 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk 2/1022 6/4839 0.372163315856723 0.999930074063124 0.935607086842689 54538/9353 2 1.86911764705882
166 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging 2/1022 6/4839 0.372163315856723 0.999930074063124 0.935607086842689 2308/23411 2 1.86911764705882
167 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 5/1022 19/4839 0.372981539767396 0.999930074063124 0.935607086842689 596/1786/1788/1789/6597 5 1.33551060542211
168 WP4141 PI3K/AKT/mTOR - VitD3 Signalling 5/1022 19/4839 0.372981539767396 0.999930074063124 0.935607086842689 2932/4609/5210/5563/6515 5 1.33551060542211
169 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 11/1022 46/4839 0.375976615531742 0.999930074063124 0.935607086842689 596/637/890/898/2252/2353/1839/3569/3726/5156/7186 11 1.17569591634874
170 WP28 Selenium Metabolism and Selenoproteins 7/1022 28/4839 0.377156251633749 0.999930074063124 0.935607086842689 1390/2353/2878/5451/54938/8991/22928 7 1.24663382594417
171 WP4481 Resistin as a regulator of inflammation 7/1022 28/4839 0.377156251633749 0.999930074063124 0.935607086842689 10000/3569/3708/5331/5332/84812/5336 7 1.24663382594417
172 WP2366 Butyrate-induced histone acetylation 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 47 1 3.73751224289912
173 WP2645 Heroin metabolism 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 1066 1 3.73751224289912
174 WP2826 Cocaine metabolism 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 1066 1 3.73751224289912
175 WP2943 Hypoxia-mediated EMT and Stemness 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 6935 1 3.73751224289912
176 WP4030 SCFA and skeletal muscle substrate metabolism 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 6517 1 3.73751224289912
177 WP4284 Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer 1/1022 2/4839 0.377830037928192 0.999930074063124 0.935607086842689 9134 1 3.73751224289912
178 WP2059 Alzheimers Disease 16/1022 69/4839 0.381749900747513 0.999930074063124 0.935607086842689 6868/322/489/637/775/1020/2906/2932/3708/23385/5331/5332/5532/5533/6263/6622 16 1.12952473836228
179 WP3931 ESC Pluripotency Pathways 19/1022 83/4839 0.387246953331721 0.999930074063124 0.935607086842689 10097/10000/2256/2258/2247/2252/2260/2353/2535/8322/8324/2932/3572/3977/5156/4092/4093/7472/7482 19 1.11083935692921
180 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 4/1022 15/4839 0.394062223247433 0.999930074063124 0.935607086842689 25924/5873/94120/94122 4 1.35952848722986
181 WP3287 Overview of nanoparticle effects 4/1022 15/4839 0.394062223247433 0.999930074063124 0.935607086842689 10000/596/3569/5742 4 1.35952848722986
182 WP4462 Platelet-mediated interactions with vascular and circulating cells 4/1022 15/4839 0.394062223247433 0.999930074063124 0.935607086842689 6347/6401/6403/7043 4 1.35952848722986
183 WP1539 Angiogenesis 6/1022 24/4839 0.396750834891395 0.999930074063124 0.935607086842689 284/2247/4846/5156/7010/7078 6 1.24639107611549
184 WP3613 Photodynamic therapy-induced unfolded protein response 6/1022 24/4839 0.396750834891395 0.999930074063124 0.935607086842689 467/811/51726/7184/10130/23645 6 1.24639107611549
185 WP4298 Viral Acute Myocarditis 16/1022 70/4839 0.406170608451993 0.999930074063124 0.935607086842689 25/596/637/835/857/1676/1677/1756/2534/2932/3569/3908/5881/6442/6443/6444 16 1.10831308445623
186 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 7/1022 29/4839 0.415474616467504 0.999930074063124 0.935607086842689 114907/2932/3479/3488/3611/84557/10891 7 1.18965517241379
187 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) 3/1022 11/4839 0.419796515080144 0.999930074063124 0.935607086842689 4609/6422/9839 3 1.40174190382728
188 WP4792 Purine metabolism 3/1022 11/4839 0.419796515080144 0.999930074063124 0.935607086842689 1716/3251/3704 3 1.40174190382728
189 WP2261 Signaling Pathways in Glioblastoma 18/1022 80/4839 0.423967332282552 0.999930074063124 0.935607086842689 10000/672/675/894/898/1017/1019/1869/54206/2260/2308/2956/4893/5156/5336/5579/5590/10253 18 1.08581801824958
190 WP4540 Pathways Regulating Hippo Signaling 18/1022 80/4839 0.423967332282552 0.999930074063124 0.935607086842689 64403/1003/2260/2774/3815/26524/4804/4915/5156/5331/5332/5563/51422/5577/5579/5590/7003/7010 18 1.08581801824958
191 WP4249 Hedgehog Signaling Pathway 8/1022 34/4839 0.430894803926012 0.999930074063124 0.935607086842689 408/596/91653/894/1455/8452/8643/8405 8 1.15035654680625
192 WP3303 RAC1/PAK1/p38/MMP2 Pathway 14/1022 62/4839 0.438037685008647 0.999930074063124 0.935607086842689 284/9068/332/1978/2308/4436/4609/4893/5888/6777/3925/7010/7075/10413 14 1.09056712962963
193 WP4008 NO/cGMP/PKG mediated Neuroprotection 6/1022 25/4839 0.438443772084916 0.999930074063124 0.935607086842689 596/817/2906/4846/4881/5138 6 1.18048072938251
194 WP3940 One carbon metabolism and related pathways 9/1022 39/4839 0.444001129236894 0.999930074063124 0.935607086842689 23743/1036/1788/2571/2878/4524/6472/6649/7298 9 1.12152023692004
195 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 4/1022 16/4839 0.44667639799645 0.999930074063124 0.935607086842689 5243/5244/5465/5914 4 1.24590700720367
196 WP4595 Urea cycle and associated pathways 4/1022 16/4839 0.44667639799645 0.999930074063124 0.935607086842689 162417/5831/10165/10166 4 1.24590700720367
197 WP4541 Hippo-Merlin Signaling Dysregulation 21/1022 95/4839 0.446750759963151 0.999930074063124 0.935607086842689 64403/1003/2260/2305/3678/3679/8516/3680/3690/3815/26524/4609/4804/4893/4915/5156/5332/94274/5577/7003/7010 21 1.06114156114156
198 WP4754 IL-18 signaling pathway 48/1022 222/4839 0.453106236341607 0.999930074063124 0.935607086842689 32/58/59/11096/321/467/596/637/274/330/7832/6347/890/9133/975/2920/1674/2023/2353/1112/2932/3068/26353/3569/3757/10365/84823/9208/4312/4322/4776/3164/51299/5579/5806/8480/22821/23623/9021/10418/6696/83931/3925/6869/7078/7185/10194/80328 48 1.03179211215747
199 WP3617 Photodynamic therapy-induced NF-kB survival signaling 7/1022 30/4839 0.453593821400876 0.999930074063124 0.935607086842689 599/330/332/2920/3569/4312/6401 7 1.1376311844078
200 WP1531 Vitamin D Metabolism 2/1022 7/4839 0.453952648610461 0.999930074063124 0.935607086842689 1593/1717 2 1.49490196078431
201 WP3672 LncRNA-mediated mechanisms of therapeutic resistance 2/1022 7/4839 0.453952648610461 0.999930074063124 0.935607086842689 5243/55384 2 1.49490196078431
202 WP3963 Mevalonate pathway 2/1022 7/4839 0.453952648610461 0.999930074063124 0.935607086842689 39/4598 2 1.49490196078431
203 WP4519 Cerebral Organic Acidurias, including diseases 2/1022 7/4839 0.453952648610461 0.999930074063124 0.935607086842689 137872/501 2 1.49490196078431
204 WP399 Wnt Signaling Pathway and Pluripotency 19/1022 86/4839 0.454472351591721 0.999930074063124 0.935607086842689 894/8061/2535/8322/8324/2932/120892/4609/85407/51701/5048/5516/5521/5579/5590/29127/7472/7482/10009 19 1.06025207958215
205 WP3646 Hepatitis C and Hepatocellular Carcinoma 10/1022 44/4839 0.45540496204186 0.999930074063124 0.935607086842689 330/332/672/1870/2487/3569/3570/4312/4609/6241 10 1.09945361543827
206 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 13/1022 58/4839 0.455650588772585 0.999930074063124 0.935607086842689 817/857/6347/3569/9636/4893/5331/5332/5336/5579/5590/6773/7297 13 1.07996916639137
207 WP455 GPCRs, Class A Rhodopsin-like 13/1022 58/4839 0.455650588772585 0.999930074063124 0.935607086842689 150/154/185/623/624/1909/1910/8477/27198/9934/5733/5734/5737 13 1.07996916639137
208 WP2865 IL1 and megakaryocytes in obesity 5/1022 21/4839 0.465289434707419 0.999930074063124 0.935607086842689 6347/2205/1839/114548/8991 5 1.16795722713864
209 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) 5/1022 21/4839 0.465289434707419 0.999930074063124 0.935607086842689 8309/5730/5737/5740/5742 5 1.16795722713864
210 WP4225 Pyrimidine metabolism and related diseases 3/1022 12/4839 0.481130404301712 0.999930074063124 0.935607086842689 790/6241/7298 3 1.2456656853124
211 WP3942 PPAR signaling pathway 10/1022 45/4839 0.486552568845093 0.999930074063124 0.935607086842689 34/8309/1593/2167/2172/3611/4312/5465/6319/10580 10 1.06775832862789
212 WP3995 Prion disease pathway 7/1022 31/4839 0.491185904868649 0.999930074063124 0.935607086842689 596/1879/2260/2534/7184/4208/4684 7 1.08994252873563
213 WP3967 miR-509-3p alteration of YAP1/ECM axis 4/1022 17/4839 0.497764149933803 0.999930074063124 0.935607086842689 1909/10082/7003/10413 4 1.14976575487381
214 WP2853 Endoderm Differentiation 24/1022 112/4839 0.505795594256087 0.999930074063124 0.935607086842689 57198/22943/1789/1847/2146/1112/2308/2627/3087/3251/9682/10459/22823/54892/51701/4830/2908/84295/6422/64321/83595/6925/9760/11169 24 1.0190380761523
215 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 1/1022 3/4839 0.509287077671294 0.999930074063124 0.935607086842689 7514 1 1.86826640548482
216 WP4342 Vitamins A and D - action mechanisms 1/1022 3/4839 0.509287077671294 0.999930074063124 0.935607086842689 5914 1 1.86826640548482
217 WP550 Biogenic Amine Synthesis 1/1022 3/4839 0.509287077671294 0.999930074063124 0.935607086842689 2571 1 1.86826640548482
218 WP733 Serotonin Receptor 2 and STAT3 Signaling 1/1022 3/4839 0.509287077671294 0.999930074063124 0.935607086842689 3717 1 1.86826640548482
219 WP364 IL-6 signaling pathway 9/1022 41/4839 0.509627652138112 0.999930074063124 0.935607086842689 2932/3569/3570/3572/3717/3726/51701/9021/7297 9 1.05086994076999
220 WP3878 ATM Signaling Network in Development and Disease 9/1022 41/4839 0.509627652138112 0.999930074063124 0.935607086842689 9212/699/983/1020/1111/11200/9759/3150/5591 9 1.05086994076999
221 WP2911 miRNA targets in ECM and membrane receptors 5/1022 22/4839 0.509955985423171 0.999930074063124 0.935607086842689 1291/1292/3913/6383/7148 5 1.09896465961016
222 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome 5/1022 22/4839 0.509955985423171 0.999930074063124 0.935607086842689 11335/1869/3066/23028/5928 5 1.09896465961016
223 WP4357 NRF2-ARE regulation 5/1022 22/4839 0.509955985423171 0.999930074063124 0.935607086842689 8452/2048/2534/2932/192111 5 1.09896465961016
224 WP465 Tryptophan metabolism 6/1022 27/4839 0.519721365903094 0.999930074063124 0.935607086842689 38/217/316/23498/11185/4129 6 1.06749156355456
225 WP2034 Leptin signaling pathway 16/1022 75/4839 0.527975666140062 0.999930074063124 0.935607086842689 32/1073/1978/2099/2308/2534/2932/3717/3953/4846/5140/5336/5563/8835/9021/6777 16 1.01304040165785
226 WP1423 Ganglio Sphingolipid Metabolism 2/1022 8/4839 0.52923088244051 0.999930074063124 0.935607086842689 30815/6489 2 1.24542483660131
227 WP2007 Iron metabolism in placenta 2/1022 8/4839 0.52923088244051 0.999930074063124 0.935607086842689 55240/7037 2 1.24542483660131
228 WP3585 Cytosine methylation 2/1022 8/4839 0.52923088244051 0.999930074063124 0.935607086842689 1786/4204 2 1.24542483660131
229 WP561 Heme Biosynthesis 2/1022 8/4839 0.52923088244051 0.999930074063124 0.935607086842689 1371/3145 2 1.24542483660131
230 WP3941 Oxidative Damage 8/1022 37/4839 0.535146493773912 0.999930074063124 0.935607086842689 596/715/716/1028/5111/7133/7185/7186 8 1.03053798544515
231 WP4312 Rett syndrome causing genes 8/1022 37/4839 0.535146493773912 0.999930074063124 0.935607086842689 2775/10014/10765/4204/4208/6597/6812/6925 8 1.03053798544515
232 WP4673 Genes involved in male infertility 18/1022 85/4839 0.538343473407803 0.999930074063124 0.935607086842689 5243/3983/596/675/1191/2099/2775/222229/4524/340719/4846/143689/8787/6649/9319/7320/7516/7517 18 1.00344889100315
233 WP1434 Osteopontin Signaling 3/1022 13/4839 0.539193661021595 0.999930074063124 0.935607086842689 3690/9020/6696 3 1.12080471050049
234 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 3/1022 13/4839 0.539193661021595 0.999930074063124 0.935607086842689 3690/8076/6263 3 1.12080471050049
235 WP3853 ERK Pathway in Huntington's Disease 3/1022 13/4839 0.539193661021595 0.999930074063124 0.935607086842689 627/4915/9252 3 1.12080471050049
236 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism 14/1022 66/4839 0.541760028083866 0.999930074063124 0.935607086842689 10000/2260/2308/2932/3690/23028/11343/4881/10891/63976/9728/6567/7067/8458 14 1.00560897435897
237 WP1742 TP53 Network 4/1022 18/4839 0.546702686733661 0.999930074063124 0.935607086842689 25/596/637/4609 4 1.0673589671625
238 WP1544 MicroRNAs in cardiomyocyte hypertrophy 16/1022 76/4839 0.551661136773016 0.999930074063124 0.935607086842689 817/2247/2535/2932/9759/10014/3479/3572/9020/4638/4776/5320/5532/5579/5592/1827 16 0.995891318754142
239 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 5/1022 23/4839 0.553022481857523 0.999930074063124 0.935607086842689 185/2201/2316/7048/7049 5 1.03763793291817
240 WP3929 Chemokine signaling pathway 26/1022 124/4839 0.5530567389186 0.999930074063124 0.935607086842689 108/196883/111/115/10000/408/6366/6376/6387/9844/2791/55970/54331/2788/2869/2932/3717/4893/5331/5332/5579/5590/5906/10235/6773/6777 26 0.990636013441521
241 WP4561 Cell migration and invasion through p75NTR 6/1022 28/4839 0.558602760703824 0.999930074063124 0.935607086842689 10000/627/1944/1945/4804/4915 6 1.01870078740157
242 WP4756 Renin Angiotensin Aldosterone System (RAAS) 6/1022 28/4839 0.558602760703824 0.999930074063124 0.935607086842689 185/817/90993/9586/1511/3708 6 1.01870078740157
243 WP363 Wnt Signaling Pathway (Netpath) 10/1022 48/4839 0.576782391898208 0.999930074063124 0.935607086842689 2932/4609/51701/8395/5579/4919/4920/6929/6925/7010 10 0.982681506136884
244 WP3888 VEGFA-VEGFR2 Signaling Pathway 84/1022 403/4839 0.577632731826315 0.999930074063124 0.935607086842689 25/32/52/9510/56999/154/81575/22899/51309/596/274/332/781/811/857/6347/10574/1003/1072/84952/79094/22820/1397/1465/22943/11080/1847/1958/1960/2048/2078/2308/6624/2534/2932/1839/9759/10014/10525/3690/9365/9079/3984/4208/4343/4629/91624/4772/4846/3164/4929/8013/55872/57326/10130/5331/5496/5563/5579/5590/5592/5717/326624/5906/1827/10231/57381/9252/1901/6386/23753/6401/114789/6546/6722/6747/10963/6886/7111/8718/7148/7170/7220/7414 84 0.981986618630983
245 WP2857 Mesodermal Commitment Pathway 24/1022 116/4839 0.583056439508221 0.999930074063124 0.935607086842689 84159/57198/22943/1789/2260/8322/2627/3251/3624/3717/9314/4211/22823/54892/51701/84295/5308/64321/6722/6925/7003/9760/11169/10413 24 0.973686503441666
246 WP3580 Methionine De Novo and Salvage Pathway 4/1022 19/4839 0.593028325924665 0.999930074063124 0.935607086842689 191/4482/253827/4953 4 0.995939751146038
247 WP197 Cholesterol Biosynthesis Pathway 3/1022 14/4839 0.593324856408773 0.999930074063124 0.935607086842689 1717/4598/6713 3 1.01864573110893
248 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity 3/1022 14/4839 0.593324856408773 0.999930074063124 0.935607086842689 1019/1869/6659 3 1.01864573110893
249 WP4558 Overview of interferons-mediated signaling pathway 3/1022 14/4839 0.593324856408773 0.999930074063124 0.935607086842689 3717/6773/7297 3 1.01864573110893
250 WP530 Cytokines and Inflammatory Response 3/1022 14/4839 0.593324856408773 0.999930074063124 0.935607086842689 1440/2920/3569 3 1.01864573110893
251 WP26 Signal Transduction of S1P Receptor 5/1022 24/4839 0.594146599480189 0.999930074063124 0.935607086842689 10000/5331/29127/1901/9294 5 0.982766651141127
252 WP3972 PDGFR-beta pathway 6/1022 29/4839 0.595940537461125 0.999930074063124 0.935607086842689 5610/2353/3717/5579/6722/6777 6 0.97415268743581
253 WP2436 Dopamine metabolism 2/1022 9/4839 0.597098605568243 0.999930074063124 0.935607086842689 4129/5516 2 1.0672268907563
254 WP3930 EDA Signalling in Hair Follicle Development 2/1022 9/4839 0.597098605568243 0.999930074063124 0.935607086842689 22943/128178 2 1.0672268907563
255 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders 2/1022 9/4839 0.597098605568243 0.999930074063124 0.935607086842689 191/1036 2 1.0672268907563
256 WP4290 Metabolic reprogramming in colon cancer 8/1022 39/4839 0.600413887507652 0.999930074063124 0.935607086842689 47/2023/2194/2618/10606/5471/5831/6472 8 0.963542660813132
257 WP51 Regulation of Actin Cytoskeleton 24/1022 117/4839 0.601698390294853 0.999930074063124 0.935607086842689 9459/623/624/1072/1073/26999/81624/2256/2258/2247/2252/2260/28964/55970/2934/3984/4638/4893/5156/5305/8395/5881/6237/7414 24 0.962958174413343
258 WP1604 Codeine and Morphine Metabolism 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 5243 1 1.24518445968005
259 WP2289 Drug Induction of Bile Acid Pathway 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 5243 1 1.24518445968005
260 WP3924 Hfe effect on hepcidin production 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 4092 1 1.24518445968005
261 WP4228 Vitamin B6-dependent and responsive disorders 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 501 1 1.24518445968005
262 WP4399 MicroRNA network associated with chronic lymphocytic leukemia 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 596 1 1.24518445968005
263 WP4524 The alternative pathway of fetal androgen synthesis 1/1022 4/4839 0.61299026349014 0.999930074063124 0.935607086842689 8630 1 1.24518445968005
264 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 8/1022 40/4839 0.631256528279167 0.999930074063124 0.935607086842689 330/6347/2932/3569/9020/8742/7185/7186 8 0.93318540433925
265 WP2332 Interleukin-11 Signaling Pathway 8/1022 40/4839 0.631256528279167 0.999930074063124 0.935607086842689 596/332/2534/3590/3572/3717/9021/7297 8 0.93318540433925
266 WP2586 Aryl Hydrocarbon Receptor Netpath 8/1022 40/4839 0.631256528279167 0.999930074063124 0.935607086842689 1017/1869/2099/1316/4609/135112/4893/84722 8 0.93318540433925
267 WP1533 Vitamin B12 Metabolism 6/1022 30/4839 0.631527216476187 0.999930074063124 0.935607086842689 6347/3569/4524/12/6472/6649 6 0.933316929133858
268 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 6/1022 30/4839 0.631527216476187 0.999930074063124 0.935607086842689 1978/2308/2932/4846/4893/7942 6 0.933316929133858
269 WP1424 Globo Sphingolipid Metabolism 4/1022 20/4839 0.636421369543438 0.999930074063124 0.935607086842689 256435/27090/30815/6489 4 0.933447937131631
270 WP262 EBV LMP1 signaling 4/1022 20/4839 0.636421369543438 0.999930074063124 0.935607086842689 9020/4215/9260/7185 4 0.933447937131631
271 WP357 Fatty Acid Biosynthesis 4/1022 20/4839 0.636421369543438 0.999930074063124 0.935607086842689 32/47/2194/6319 4 0.933447937131631
272 WP254 Apoptosis 16/1022 80/4839 0.64167988935281 0.999930074063124 0.935607086842689 596/599/637/330/332/835/1676/1677/3070/3479/3663/4609/7133/8718/7185/7186 16 0.93265407554672
273 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 3/1022 15/4839 0.643140514699108 0.999930074063124 0.935607086842689 3708/4893/6722 3 0.93351324828263
274 WP2333 Trans-sulfuration pathway 2/1022 10/4839 0.657325940610943 0.999930074063124 0.935607086842689 191/1786 2 0.933578431372549
275 WP3630 NAD metabolism, sirtuins and aging 2/1022 10/4839 0.657325940610943 0.999930074063124 0.935607086842689 2308/23411 2 0.933578431372549
276 WP3892 Development of pulmonary dendritic cells and macrophage subsets 2/1022 10/4839 0.657325940610943 0.999930074063124 0.935607086842689 3398/6925 2 0.933578431372549
277 WP3971 Role of Osx and miRNAs in tooth development 2/1022 10/4839 0.657325940610943 0.999930074063124 0.935607086842689 22943/9314 2 0.933578431372549
278 WP3651 Pathways Affected in Adenoid Cystic Carcinoma 11/1022 56/4839 0.659389444502175 0.999930074063124 0.935607086842689 84159/672/1111/11200/93986/9863/4602/4609/4781/5591/29128 11 0.91201230904495
279 WP560 TGF-beta Receptor Signaling 9/1022 46/4839 0.659799833104285 0.999930074063124 0.935607086842689 2353/3624/4092/4093/6696/7048/7049/9839/23090 9 0.907659881006377
280 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) 8/1022 41/4839 0.660742316434575 0.999930074063124 0.935607086842689 9023/1593/1717/10682/2194/4598/6319/6713 8 0.904667981591059
281 WP2371 Parkinsons Disease Pathway 6/1022 31/4839 0.665209131261997 0.999930074063124 0.935607086842689 835/898/9134/120892/6622/23208 6 0.895748031496063
282 WP3527 Preimplantation Embryo 6/1022 31/4839 0.665209131261997 0.999930074063124 0.935607086842689 1958/2354/9314/4306/6597/7538 6 0.895748031496063
283 WP619 Type II interferon signaling (IFNG) 6/1022 31/4839 0.665209131261997 0.999930074063124 0.935607086842689 5610/2537/9636/3717/9021/6773 6 0.895748031496063
284 WP4262 Breast cancer pathway 24/1022 121/4839 0.672534826004334 0.999930074063124 0.935607086842689 10000/672/675/1019/1457/1869/1870/2099/2247/2252/2260/2353/2535/8324/4616/2932/3479/3815/4609/4893/5241/5888/7472/7482 24 0.922256884903828
285 WP4482 Vitamin D in inflammatory diseases 4/1022 21/4839 0.676687707151914 0.999930074063124 0.935607086842689 1843/3569/4772/2908 4 0.878308101236565
286 WP138 Androgen receptor signaling pathway 16/1022 82/4839 0.683077882553455 0.999930074063124 0.935607086842689 672/811/857/898/11034/2288/2316/2308/2932/8850/23028/5883/5901/388/23411/7041 16 0.903909874088801
287 WP107 Translation Factors 9/1022 47/4839 0.68642269962721 0.999930074063124 0.935607086842689 1915/1933/1936/27102/5610/1975/1978/1979/8637 9 0.883540291993557
288 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 3/1022 16/4839 0.688478387784337 0.999930074063124 0.935607086842689 2146/22823/5928 3 0.86147807050653
289 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 3/1022 16/4839 0.688478387784337 0.999930074063124 0.935607086842689 8324/2932/6925 3 0.86147807050653
290 WP3927 BMP Signaling Pathway in Eyelid Development 3/1022 16/4839 0.688478387784337 0.999930074063124 0.935607086842689 3625/5308/6422 3 0.86147807050653
291 WP4331 Neovascularisation processes 7/1022 37/4839 0.692135111733692 0.999930074063124 0.935607086842689 94/284/6387/2048/3815/4093/7043 7 0.870574712643678
292 WP2805 exRNA mechanism of action and biogenesis 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 57510 1 0.933643486777669
293 WP311 Synthesis and Degradation of Ketone Bodies 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 38 1 0.933643486777669
294 WP3596 miR-517 relationship with ARCN1 and USP1 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 3398 1 0.933643486777669
295 WP4147 PTF1A related regulatory pathway 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 8850 1 0.933643486777669
296 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 79017 1 0.933643486777669
297 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 1/1022 5/4839 0.694794596626247 0.999930074063124 0.935607086842689 2053 1 0.933643486777669
298 WP2870 Extracellular vesicle-mediated signaling in recipient cells 5/1022 27/4839 0.703691151331918 0.999930074063124 0.935607086842689 3082/4893/7043/7048/7049 5 0.848082595870207
299 WP4150 Wnt Signaling in Kidney Disease 5/1022 27/4839 0.703691151331918 0.999930074063124 0.935607086842689 2535/8322/8324/7472/7482 5 0.848082595870207
300 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 24/1022 123/4839 0.705339946522517 0.999930074063124 0.935607086842689 32/6868/627/1020/1072/1457/1808/1958/1959/1978/2353/2534/2932/3717/4208/4684/4776/4804/4915/5563/5906/9252/6696/6777 24 0.90313961255845
301 WP4239 Epithelial to mesenchymal transition in colorectal cancer 25/1022 128/4839 0.706030484524258 0.999930074063124 0.935607086842689 10000/5010/7122/1286/1288/2146/2305/2535/8322/8324/2932/3398/3678/26524/4209/5310/5928/7043/7048/117581/7472/7482/7483/6935/9839 25 0.904168817131005
302 WP2290 RalA downstream regulated genes 2/1022 11/4839 0.710110257395565 0.999930074063124 0.935607086842689 4893/5881 2 0.82962962962963
303 WP4495 IL-10 Anti-inflammatory Signaling Pathway 2/1022 11/4839 0.710110257395565 0.999930074063124 0.935607086842689 3569/6773 2 0.82962962962963
304 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma 2/1022 11/4839 0.710110257395565 0.999930074063124 0.935607086842689 2146/84759 2 0.82962962962963
305 WP4629 Computational Model of Aerobic Glycolysis 2/1022 11/4839 0.710110257395565 0.999930074063124 0.935607086842689 2023/7167 2 0.82962962962963
306 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 4/1022 22/4839 0.713739200869411 0.999930074063124 0.935607086842689 374/627/1978/2308 4 0.829294913774285
307 WP716 Vitamin A and Carotenoid Metabolism 4/1022 22/4839 0.713739200869411 0.999930074063124 0.935607086842689 83875/5914/5947/116362 4 0.829294913774285
308 WP127 IL-5 Signaling Pathway 7/1022 38/4839 0.720091281028044 0.999930074063124 0.935607086842689 596/695/2353/2932/3717/4609/6777 7 0.842269187986652
309 WP2828 Bladder Cancer 7/1022 38/4839 0.720091281028044 0.999930074063124 0.935607086842689 1019/1869/1839/4312/4609/4893/9252 7 0.842269187986652
310 WP2875 Constitutive Androstane Receptor Pathway 3/1022 17/4839 0.729345724466594 0.999930074063124 0.935607086842689 5243/2308/10891 3 0.79973363241273
311 WP3645 NAD+ biosynthetic pathways 3/1022 17/4839 0.729345724466594 0.999930074063124 0.935607086842689 683/10038/23411 3 0.79973363241273
312 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 3/1022 17/4839 0.729345724466594 0.999930074063124 0.935607086842689 2252/5310/23411 3 0.79973363241273
313 WP4747 Netrin-UNC5B signaling Pathway 8/1022 44/4839 0.740317238416276 0.999930074063124 0.935607086842689 6347/1003/2534/9423/56963/54538/6401/10413 8 0.828621520929213
314 WP12 Osteoclast Signaling 2/1022 12/4839 0.755906228014336 0.999930074063124 0.935607086842689 3690/6696 2 0.746470588235294
315 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 2/1022 12/4839 0.755906228014336 0.999930074063124 0.935607086842689 9020/6237 2 0.746470588235294
316 WP4724 Omega-9 FA synthesis 2/1022 12/4839 0.755906228014336 0.999930074063124 0.935607086842689 2194/6319 2 0.746470588235294
317 WP15 Selenium Micronutrient Network 9/1022 50/4839 0.758229156843588 0.999930074063124 0.935607086842689 6347/80308/2878/3569/4524/5742/22928/12/6649 9 0.818240916861291
318 WP2249 Metastatic brain tumor 1/1022 6/4839 0.759320852780151 0.999930074063124 0.935607086842689 4609 1 0.746718903036239
319 WP2456 HIF1A and PPARG regulation of glycolysis 1/1022 6/4839 0.759320852780151 0.999930074063124 0.935607086842689 7167 1 0.746718903036239
320 WP2485 NAD Biosynthesis II (from tryptophan) 1/1022 6/4839 0.759320852780151 0.999930074063124 0.935607086842689 23498 1 0.746718903036239
321 WP3655 Hypothetical Craniofacial Development Pathway 1/1022 6/4839 0.759320852780151 0.999930074063124 0.935607086842689 7043 1 0.746718903036239
322 WP4216 Chromosomal and microsatellite instability in colorectal cancer 13/1022 71/4839 0.763504992842297 0.999930074063124 0.935607086842689 10000/596/332/2353/4616/2932/4436/2956/4609/9423/5881/7043/7048 13 0.83501930897782
323 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 8/1022 45/4839 0.763755951174917 0.999930074063124 0.935607086842689 695/1978/2534/3569/3717/4609/6777/85480 8 0.806013113705421
324 WP408 Oxidative Stress 5/1022 29/4839 0.764251182556945 0.999930074063124 0.935607086842689 2353/2878/3726/4784/6649 5 0.776999344477221
325 WP2876 Pregnane X Receptor pathway 3/1022 18/4839 0.765874332013181 0.999930074063124 0.935607086842689 5243/2308/10891 3 0.746221786064769
326 WP404 Nucleotide Metabolism 3/1022 18/4839 0.765874332013181 0.999930074063124 0.935607086842689 3251/5424/6241 3 0.746221786064769
327 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells 3/1022 18/4839 0.765874332013181 0.999930074063124 0.935607086842689 4893/5873/6237 3 0.746221786064769
328 WP4533 Transcription co-factors SKI and SKIL protein partners 3/1022 18/4839 0.765874332013181 0.999930074063124 0.935607086842689 26524/4204/7003 3 0.746221786064769
329 WP268 Notch Signaling 7/1022 40/4839 0.77066765868094 0.999930074063124 0.935607086842689 6868/151636/3066/2648/8850/4242/23385 7 0.790804597701149
330 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 7/1022 40/4839 0.77066765868094 0.999930074063124 0.935607086842689 58/596/1676/1677/4001/84823/5591 7 0.790804597701149
331 WP185 Integrin-mediated Cell Adhesion 16/1022 87/4839 0.773755263751992 0.999930074063124 0.935607086842689 10000/857/2534/3611/3678/3679/8516/3680/3690/5881/5906/10580/7094/7145/7414/7791 16 0.839134208831518
332 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 10/1022 56/4839 0.774278860742701 0.999930074063124 0.935607086842689 32/890/891/1978/2194/3953/133522/5563/51422/6517 10 0.810061866300052
333 WP3529 Zinc homeostasis 4/1022 24/4839 0.77825983963447 0.999930074063124 0.935607086842689 4499/55676/201266/55630 4 0.745972495088409
334 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation 4/1022 24/4839 0.77825983963447 0.999930074063124 0.935607086842689 4882/5745/5933/7067 4 0.745972495088409
335 WP366 TGF-beta Signaling Pathway 24/1022 128/4839 0.778583806473659 0.999930074063124 0.935607086842689 467/857/9133/983/2353/2354/3690/3726/3727/7071/1316/4208/4312/4321/4609/5933/4092/7027/7041/7048/7049/10413/6935/9839 24 0.858563280406968
336 WP2795 Cardiac Hypertrophic Response 9/1022 51/4839 0.779407731793952 0.999930074063124 0.935607086842689 817/2247/2932/9759/10014/3479/9020/5320/5592 9 0.798547454519814
337 WP524 G13 Signaling Pathway 6/1022 35/4839 0.779438941079249 0.999930074063124 0.935607086842689 1072/1073/11113/3984/5305/6242 6 0.771382025522672
338 WP2328 Allograft Rejection 11/1022 62/4839 0.78878849901806 0.999930074063124 0.935607086842689 5243/185/23743/718/730/6366/6387/120892/5156/5590/7431 11 0.803436706037509
339 WP2369 Histone Modifications 5/1022 30/4839 0.790795975773096 0.999930074063124 0.935607086842689 2146/26040/80854/9869/56950 5 0.745722713864307
340 WP2447 Amyotrophic lateral sclerosis (ALS) 5/1022 30/4839 0.790795975773096 0.999930074063124 0.935607086842689 596/637/1471/5532/5533 5 0.745722713864307
341 WP49 IL-2 Signaling Pathway 7/1022 41/4839 0.793299346790486 0.999930074063124 0.935607086842689 596/894/2353/2534/4609/9021/6777 7 0.767342799188641
342 WP4504 Cysteine and methionine catabolism 2/1022 13/4839 0.795308512922107 0.999930074063124 0.935607086842689 191/1036 2 0.67843137254902
343 WP4705 Pathways of nucleic acid metabolism and innate immune sensing 2/1022 13/4839 0.795308512922107 0.999930074063124 0.935607086842689 103/10535 2 0.67843137254902
344 WP585 Interferon type I signaling pathways 9/1022 52/4839 0.799212112621598 0.999930074063124 0.935607086842689 1975/1978/2534/27250/5906/9252/9021/6773/7297 9 0.779769967170963
345 WP4565 Neural Crest Cell Migration in Cancer 6/1022 36/4839 0.802839816817109 0.999930074063124 0.935607086842689 10000/627/2048/2353/4804/4915 6 0.745472440944882
346 WP205 IL-7 Signaling Pathway 4/1022 25/4839 0.80591460788313 0.999930074063124 0.935607086842689 2534/2932/4609/6777 4 0.710262887080176
347 WP106 Alanine and aspartate metabolism 1/1022 7/4839 0.8102155534751 0.999930074063124 0.935607086842689 2571 1 0.622102513875286
348 WP229 Irinotecan Pathway 1/1022 7/4839 0.8102155534751 0.999930074063124 0.935607086842689 1066 1 0.622102513875286
349 WP4236 Disorders of the Krebs cycle 1/1022 7/4839 0.8102155534751 0.999930074063124 0.935607086842689 55526 1 0.622102513875286
350 WP4507 Molybdenum cofactor (Moco) biosynthesis 1/1022 7/4839 0.8102155534751 0.999930074063124 0.935607086842689 316 1 0.622102513875286
351 WP704 Methylation Pathways 1/1022 7/4839 0.8102155534751 0.999930074063124 0.935607086842689 11185 1 0.622102513875286
352 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions 5/1022 31/4839 0.814947292025231 0.999930074063124 0.935607086842689 2308/26524/5906/7003/10413 5 0.716851977913925
353 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) 3/1022 20/4839 0.82684676790972 0.999930074063124 0.935607086842689 8309/4056/5465 3 0.658084627374011
354 WP4725 Sphingolipid Metabolism (general overview) 3/1022 20/4839 0.82684676790972 0.999930074063124 0.935607086842689 29956/166929/6609 3 0.658084627374011
355 WP304 Kit receptor signaling pathway 10/1022 59/4839 0.828430322217722 0.999930074063124 0.935607086842689 596/695/2353/2534/3717/3726/3815/4286/5579/6777 10 0.759861256755667
356 WP1584 Type II diabetes mellitus 2/1022 14/4839 0.828972455674329 0.999930074063124 0.935607086842689 5590/6517 2 0.621732026143791
357 WP1946 Cori Cycle 2/1022 14/4839 0.828972455674329 0.999930074063124 0.935607086842689 6517/7167 2 0.621732026143791
358 WP3644 NAD+ metabolism 2/1022 14/4839 0.828972455674329 0.999930074063124 0.935607086842689 4907/23411 2 0.621732026143791
359 WP2884 NRF2 pathway 17/1022 96/4839 0.829421211575612 0.999930074063124 0.935607086842689 1066/1958/2042/2258/2878/2949/1839/3082/23764/6515/6517/201266/55630/8884/6533/6649/7048 17 0.800377857547705
360 WP3981 miRNA regulation of prostate cancer signaling pathways 5/1022 32/4839 0.836811213554681 0.999930074063124 0.935607086842689 10000/596/90993/2308/2932 5 0.690119814996904
361 WP673 ErbB Signaling Pathway 14/1022 81/4839 0.839063333601451 0.999930074063124 0.935607086842689 25/10000/374/817/1978/2308/2932/1839/4609/4893/9542/5336/5579/6777 14 0.777363184079602
362 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 4524 1 0.533090807331748
363 WP288 NLR Proteins 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 2048 1 0.533090807331748
364 WP3634 Insulin signalling in human adipocytes (normal condition) 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 6517 1 0.533090807331748
365 WP3635 Insulin signalling in human adipocytes (diabetic condition) 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 6517 1 0.533090807331748
366 WP3871 Valproic acid pathway 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 36 1 0.533090807331748
367 WP3934 Leptin and adiponectin 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 3953 1 0.533090807331748
368 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 3569 1 0.533090807331748
369 WP4742 Ketogenesis and Ketolysis 1/1022 8/4839 0.850356220765755 0.999930074063124 0.935607086842689 38 1 0.533090807331748
370 WP286 IL-3 Signaling Pathway 7/1022 44/4839 0.851044950413995 0.999930074063124 0.935607086842689 596/969/2353/2534/3563/3717/6777 7 0.704566635601118
371 WP2509 Nanoparticle triggered autophagic cell death 3/1022 21/4839 0.851873278036022 0.999930074063124 0.935607086842689 596/10036/84557 3 0.621360811252862
372 WP4726 Sphingolipid Metabolism (integrated pathway) 3/1022 21/4839 0.851873278036022 0.999930074063124 0.935607086842689 29956/166929/6609 3 0.621360811252862
373 WP712 Estrogen signaling pathway 3/1022 21/4839 0.851873278036022 0.999930074063124 0.935607086842689 596/2099/2353 3 0.621360811252862
374 WP2112 IL17 signaling pathway 4/1022 27/4839 0.852782578619521 0.999930074063124 0.935607086842689 1052/2932/3717/9020 4 0.648159220978902
375 WP437 EGF/EGFR Signaling Pathway 28/1022 155/4839 0.853072181335939 0.999930074063124 0.935607086842689 25/6790/857/1072/1869/1978/54206/2353/2354/2308/3717/3727/4215/4208/4209/4605/4846/5111/5579/5590/5906/6196/9252/10253/10617/6777/3925/6812 28 0.81845403127426
376 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 5/1022 33/4839 0.856512069472329 0.999930074063124 0.935607086842689 284/637/332/6515/7043 5 0.665297092288243
377 WP400 p38 MAPK Signaling Pathway 5/1022 33/4839 0.856512069472329 0.999930074063124 0.935607086842689 3150/4209/4609/9252/7186 5 0.665297092288243
378 WP422 MAPK Cascade 5/1022 33/4839 0.856512069472329 0.999930074063124 0.935607086842689 4215/4893/5331/22821/6237 5 0.665297092288243
379 WP4564 Neural Crest Cell Migration during Development 5/1022 33/4839 0.856512069472329 0.999930074063124 0.935607086842689 10000/627/2048/2353/4804 5 0.665297092288243
380 WP4758 Nephrotic syndrome 5/1022 33/4839 0.856512069472329 0.999930074063124 0.935607086842689 54443/83478/1286/3913/11346 5 0.665297092288243
381 WP615 Senescence and Autophagy in Cancer 16/1022 93/4839 0.856950684897775 0.999930074063124 0.935607086842689 596/1869/23710/2932/2934/3479/3488/3569/3570/3572/3624/3663/84557/81631/5111/55630 16 0.77250781028117
382 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus 2/1022 15/4839 0.857561985055132 0.999930074063124 0.935607086842689 166929/256435 2 0.573755656108597
383 WP430 Statin Pathway 2/1022 15/4839 0.857561985055132 0.999930074063124 0.935607086842689 341/6713 2 0.573755656108597
384 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 8/1022 50/4839 0.858253018221591 0.999930074063124 0.935607086842689 25/332/3070/3727/4092/9021/7185/7431 8 0.709119939889171
385 WP231 TNF alpha Signaling Pathway 15/1022 88/4839 0.860413949541904 0.999930074063124 0.935607086842689 637/330/6347/1457/3569/9020/4215/1326/4893/5347/5590/6401/7133/7185/7186 15 0.763967297411272
386 WP4566 Translation inhibitors in chronically activated PDGFRA cells 7/1022 45/4839 0.867124502905404 0.999930074063124 0.935607086842689 10000/1457/1975/1978/27250/6196/9252 7 0.685843920145191
387 WP2643 Nanoparticle-mediated activation of receptor signaling 4/1022 28/4839 0.872374324086727 0.999930074063124 0.935607086842689 10000/374/4893/7094 4 0.620988867059594
388 WP4223 Ras Signaling 25/1022 142/4839 0.875522194317694 0.999930074063124 0.935607086842689 25/10000/2260/2791/55970/54331/2788/3815/4804/4893/4915/5156/5320/8605/5336/5579/5881/5906/22821/10156/8437/10235/23179/6237/7010 25 0.792977222265086
389 WP1772 Apoptosis Modulation and Signaling 13/1022 79/4839 0.879929154875462 0.999930074063124 0.935607086842689 9531/596/599/637/330/332/835/1676/1677/2353/9020/7133/8718 13 0.732243145028081
390 WP3413 NOTCH1 regulation of human endothelial cell calcification 2/1022 16/4839 0.881716784665246 0.999930074063124 0.935607086842689 1902/4256 2 0.532633053221289
391 WP391 Mitochondrial Gene Expression 2/1022 16/4839 0.881716784665246 0.999930074063124 0.935607086842689 10891/133522 2 0.532633053221289
392 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 1/1022 9/4839 0.882013422665444 0.999930074063124 0.935607086842689 23764 1 0.466332027424094
393 WP698 Glucuronidation 1/1022 9/4839 0.882013422665444 0.999930074063124 0.935607086842689 5239 1 0.466332027424094
394 WP411 mRNA Processing 21/1022 122/4839 0.883577816383176 0.999930074063124 0.935607086842689 10659/1196/29894/51692/1478/9343/3191/56339/4841/5496/55660/5725/6626/6628/6632/6635/6636/6637/8405/10772/6430 21 0.771861801564772
395 WP4685 Melanoma 10/1022 63/4839 0.88442190556457 0.999930074063124 0.935607086842689 10000/1019/1869/1870/2353/4616/3815/4286/4893/7414 10 0.701767469609964
396 WP4197 The human immune response to tuberculosis 3/1022 23/4839 0.892600365127733 0.999930074063124 0.935607086842689 3717/6773/7297 3 0.558930323846909
397 WP4537 Hippo-Yap signaling pathway 3/1022 23/4839 0.892600365127733 0.999930074063124 0.935607086842689 26524/7003/23043 3 0.558930323846909
398 WP3286 Copper homeostasis 7/1022 47/4839 0.89500690547911 0.999930074063124 0.935607086842689 6868/2308/2932/22823/6649/55240/79689 7 0.651206896551724
399 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 2/1022 17/4839 0.902032926025066 0.999930074063124 0.935607086842689 7428/7472 2 0.496993464052288
400 WP4155 Endometrial cancer 9/1022 59/4839 0.902327265856976 0.999930074063124 0.935607086842689 10000/2247/2260/2353/4616/2932/3611/4609/4893 9 0.669358341559724
401 WP500 Glycogen Synthesis and Degradation 5/1022 36/4839 0.904032070792873 0.999930074063124 0.935607086842689 2932/5516/5521/5525/5837 5 0.600437720049481
402 WP3676 BDNF-TrkB Signaling 4/1022 30/4839 0.904886034571245 0.999930074063124 0.935607086842689 627/1978/4893/4915 4 0.572918240894665
403 WP4241 Type 2 papillary renal cell carcinoma 4/1022 30/4839 0.904886034571245 0.999930074063124 0.935607086842689 81578/7942/7043/7428 4 0.572918240894665
404 WP43 Oxidation by Cytochrome P450 4/1022 30/4839 0.904886034571245 0.999930074063124 0.935607086842689 1727/57404/1593/51302 4 0.572918240894665
405 WP4496 Signal transduction through IL1R 4/1022 30/4839 0.904886034571245 0.999930074063124 0.935607086842689 3569/11213/9020/7043 4 0.572918240894665
406 WP4666 Hepatitis B infection 22/1022 130/4839 0.905470089093815 0.999930074063124 0.935607086842689 10000/596/637/332/90993/9586/1959/1960/2353/3569/3717/4609/4772/4776/4893/5111/5579/6773/6777/7043/7048/7297 22 0.755537037037037
407 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 1/1022 10/4839 0.906978698449278 0.999930074063124 0.935607086842689 10766 1 0.414408531940363
408 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 1/1022 10/4839 0.906978698449278 0.999930074063124 0.935607086842689 5590 1 0.414408531940363
409 WP438 Non-homologous end joining 1/1022 10/4839 0.906978698449278 0.999930074063124 0.935607086842689 5591 1 0.414408531940363
410 WP1422 Sphingolipid pathway 3/1022 24/4839 0.908934725912484 0.999930074063124 0.935607086842689 29956/57515/166929 3 0.532174400672929
411 WP2636 Common Pathways Underlying Drug Addiction 3/1022 24/4839 0.908934725912484 0.999930074063124 0.935607086842689 72/5579/5906 3 0.532174400672929
412 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment 3/1022 24/4839 0.908934725912484 0.999930074063124 0.935607086842689 6347/7043/7048 3 0.532174400672929
413 WP3925 Amino Acid metabolism 10/1022 66/4839 0.915791648477362 0.999930074063124 0.935607086842689 34/47/126/5832/501/8639/790/4953/5166/5831 10 0.663643421795596
414 WP4659 Gastrin Signaling Pathway 17/1022 105/4839 0.918594120239461 0.999930074063124 0.935607086842689 408/330/332/1958/1978/2353/2308/2534/2932/3717/3815/9314/4208/4209/4609/388/6925 17 0.716791044776119
415 WP384 Apoptosis Modulation by HSP70 2/1022 18/4839 0.919052750276552 0.999930074063124 0.935607086842689 637/835 2 0.465808823529412
416 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 2/1022 18/4839 0.919052750276552 0.999930074063124 0.935607086842689 1978/55872 2 0.465808823529412
417 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 8/1022 55/4839 0.919649796928562 0.999930074063124 0.935607086842689 58/10097/2535/8322/8324/2932/4609/4638 8 0.632842334969995
418 WP4521 Glycosylation and related congenital defects 3/1022 25/4839 0.922982923825578 0.999930074063124 0.935607086842689 10195/79053/7841 3 0.507850834151129
419 WP4255 Non-small cell lung cancer 10/1022 67/4839 0.924503025461715 0.999930074063124 0.935607086842689 10000/637/1019/1869/1870/4616/4893/5336/5579/6777 10 0.651827196449622
420 WP4210 Tryptophan catabolism leading to NAD+ production 1/1022 11/4839 0.926665542554649 0.999930074063124 0.935607086842689 23498 1 0.372869735553379
421 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms 6/1022 44/4839 0.926932208481225 0.999930074063124 0.935607086842689 58/59/70/72/3690/7003 6 0.587287608785744
422 WP2037 Prolactin Signaling Pathway 11/1022 73/4839 0.927200501963799 0.999930074063124 0.935607086842689 1978/2316/2353/2534/2932/3717/4609/6196/8835/9021/6777 11 0.658961105261479
423 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 7/1022 50/4839 0.927464167576974 0.999930074063124 0.935607086842689 1019/2353/2534/2932/9020/1326/6237 7 0.605292702485966
424 WP4018 Pathways in clear cell renal cell carcinoma 12/1022 79/4839 0.929965465976983 0.999930074063124 0.935607086842689 32/47/2023/2194/5156/6472/8082/7043/84969/7167/7428/6935 12 0.664991872321561
425 WP2507 Nanomaterial induced apoptosis 2/1022 19/4839 0.933260961114407 0.999930074063124 0.935607086842689 596/637 2 0.438292964244521
426 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway 2/1022 19/4839 0.933260961114407 0.999930074063124 0.935607086842689 32/8452 2 0.438292964244521
427 WP2324 AGE/RAGE pathway 9/1022 63/4839 0.938090580026804 0.999930074063124 0.935607086842689 1650/2308/3625/3717/4322/4846/5579/5590/6777 9 0.619118130964133
428 WP534 Glycolysis and Gluconeogenesis 4/1022 33/4839 0.93995275510931 0.999930074063124 0.935607086842689 2023/6515/6517/7167 4 0.513244360138202
429 WP23 B Cell Receptor Signaling Pathway 14/1022 92/4839 0.941630174229579 0.999930074063124 0.935607086842689 695/933/974/975/2308/2534/2932/3608/4208/4209/4609/8395/5336/5579 14 0.665776353276353
430 WP3933 Kennedy pathway from Sphingolipids 1/1022 12/4839 0.942189116603769 0.999930074063124 0.935607086842689 9791 1 0.338883447600392
431 WP47 Hedgehog Signaling Pathway Netpath 1/1022 12/4839 0.942189116603769 0.999930074063124 0.935607086842689 8643 1 0.338883447600392
432 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 9/1022 64/4839 0.945010014311913 0.999930074063124 0.935607086842689 47/2194/133522/5563/51422/6319/23411/6713/7528 9 0.607699901283317
433 WP143 Fatty Acid Beta Oxidation 3/1022 27/4839 0.945300222572607 0.999930074063124 0.935607086842689 34/38/7167 3 0.465284592737978
434 WP4549 Fragile X Syndrome 14/1022 93/4839 0.947247505263619 0.999930074063124 0.935607086842689 627/26999/1915/1979/2534/2571/3708/4131/4204/4915/5909/6895/51256/9675 14 0.657172995780591
435 WP2359 Parkin-Ubiquitin Proteasomal System pathway 8/1022 59/4839 0.950773104125175 0.999930074063124 0.935607086842689 898/3306/5717/10213/5709/6622/10381/84617 8 0.582588854082067
436 WP395 IL-4 Signaling Pathway 7/1022 53/4839 0.95079351505702 0.999930074063124 0.935607086842689 332/2316/2353/3717/9021/6777/7297 7 0.565367316341829
437 WP4159 GABA receptor Signaling 1/1022 13/4839 0.954429166910574 0.999930074063124 0.935607086842689 2571 1 0.310561540972902
438 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 2/1022 21/4839 0.954896495340778 0.999930074063124 0.935607086842689 1066/2353 2 0.391950464396285
439 WP4585 Cancer immunotherapy by PD-1 blockade 2/1022 21/4839 0.954896495340778 0.999930074063124 0.935607086842689 4772/4776 2 0.391950464396285
440 WP195 IL-1 signaling pathway 7/1022 55/4839 0.962362888607297 0.999930074063124 0.935607086842689 6347/3316/11213/9020/4215/57161/5590 7 0.541522988505747
441 WP4313 Ferroptosis 4/1022 36/4839 0.962835157966289 0.999930074063124 0.935607086842689 84557/81631/55240/7037 4 0.464759332023576
442 WP3845 Canonical and Non-canonical Notch signaling 2/1022 22/4839 0.963017752694939 0.999930074063124 0.935607086842689 4237/6237 2 0.372254901960784
443 WP453 Inflammatory Response Pathway 2/1022 22/4839 0.963017752694939 0.999930074063124 0.935607086842689 3913/7133 2 0.372254901960784
444 WP2637 Structural Pathway of Interleukin 1 (IL-1) 6/1022 49/4839 0.963456690090173 0.999930074063124 0.935607086842689 2353/9020/4215/1326/4609/9252 6 0.518311664530306
445 WP3 Phytochemical activity on NRF2 transcriptional activation 1/1022 14/4839 0.964079683159516 0.999930074063124 0.935607086842689 2048 1 0.286596850749642
446 WP4478 LTF danger signal response pathway 1/1022 14/4839 0.964079683159516 0.999930074063124 0.935607086842689 3569 1 0.286596850749642
447 WP3982 miRNA regulation of p53 pathway in prostate cancer 2/1022 23/4839 0.969724170558482 0.999930074063124 0.935607086842689 637/11200 2 0.354435107376284
448 WP4656 Joubert Syndrome 9/1022 69/4839 0.970349721382535 0.999930074063124 0.935607086842689 57545/95681/2316/261734/5108/117177/79867/9094/23090 9 0.556317867719645
449 WP61 Notch Signaling Pathway Netpath 7/1022 57/4839 0.971411720535189 0.999930074063124 0.935607086842689 6868/2273/2932/3066/3717/4609/23385 7 0.519586206896552
450 WP22 IL-9 Signaling Pathway 1/1022 15/4839 0.971688090166972 0.999930074063124 0.935607086842689 6777 1 0.266055687701133
451 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 1/1022 15/4839 0.971688090166972 0.999930074063124 0.935607086842689 47 1 0.266055687701133
452 WP481 Insulin Signaling 23/1022 150/4839 0.972563063883818 0.999930074063124 0.935607086842689 1958/30846/1978/5167/2353/2308/2932/9020/4215/1326/5563/5579/5590/57381/6196/9252/6236/6517/9021/10580/6722/6812/6844 23 0.668936653188622
453 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway 6/1022 51/4839 0.972661216837911 0.999930074063124 0.935607086842689 6387/8653/9636/54941/80143/7186 6 0.49501312335958
454 WP2873 Aryl Hydrocarbon Receptor Pathway 3/1022 31/4839 0.973077357447465 0.999930074063124 0.935607086842689 10486/3726/3727 3 0.398394784803028
455 WP183 Proteasome Degradation 7/1022 58/4839 0.975146089269106 0.999930074063124 0.935607086842689 5690/5691/5717/5709/6184/6185/7320 7 0.509263015551048
456 WP100 Glutathione metabolism 1/1022 16/4839 0.97768617720042 0.999930074063124 0.935607086842689 2878 1 0.248253346392426
457 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 1/1022 16/4839 0.97768617720042 0.999930074063124 0.935607086842689 34 1 0.248253346392426
458 WP4494 Selective expression of chemokine receptors during T-cell polarization 1/1022 16/4839 0.97768617720042 0.999930074063124 0.935607086842689 7043 1 0.248253346392426
459 WP2533 Glycerophospholipid Biosynthetic Pathway 2/1022 25/4839 0.979795488915296 0.999930074063124 0.935607086842689 5320/9791 2 0.323444160272805
460 WP3851 TLR4 Signaling and Tolerance 2/1022 25/4839 0.979795488915296 0.999930074063124 0.935607086842689 3569/11213 2 0.323444160272805
461 WP581 EPO Receptor Signaling 2/1022 25/4839 0.979795488915296 0.999930074063124 0.935607086842689 3717/6777 2 0.323444160272805
462 WP244 Alpha 6 Beta 4 signaling pathway 3/1022 33/4839 0.981310074990616 0.999930074063124 0.935607086842689 1978/3908/3913 3 0.371638861629048
463 WP4263 Pancreatic adenocarcinoma pathway 11/1022 85/4839 0.981895728220499 0.999930074063124 0.935607086842689 10000/9459/675/1019/1869/1870/4616/5881/5888/7043/7048 11 0.550338171999893
464 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 1/1022 17/4839 0.98241450539888 0.999930074063124 0.935607086842689 7431 1 0.232676297747307
465 WP3874 Canonical and Non-Canonical TGF-B signaling 1/1022 17/4839 0.98241450539888 0.999930074063124 0.935607086842689 7048 1 0.232676297747307
466 WP405 Eukaryotic Transcription Initiation 4/1022 41/4839 0.983902757348175 0.999930074063124 0.935607086842689 2960/3611/5436/5437 4 0.401423034036001
467 WP1471 Target Of Rapamycin (TOR) Signaling 3/1022 34/4839 0.984463797563015 0.999930074063124 0.935607086842689 1978/5563/51422 3 0.35955554148596
468 WP313 Signaling of Hepatocyte Growth Factor Receptor 3/1022 34/4839 0.984463797563015 0.999930074063124 0.935607086842689 2353/3082/5906 3 0.35955554148596
469 WP4655 Cytosolic DNA-sensing pathway 6/1022 55/4839 0.98499866511702 0.999930074063124 0.935607086842689 103/90865/3569/9636/5437/54941 6 0.454121806202796
470 WP4722 Glycerolipids and Glycerophospholipids 1/1022 18/4839 0.986141667464899 0.999930074063124 0.935607086842689 9791 1 0.218931843060437
471 WP2583 T-Cell Receptor and Co-stimulatory Signaling 2/1022 27/4839 0.986584860633084 0.999930074063124 0.935607086842689 2534/2932 2 0.297411764705882
472 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway 4/1022 43/4839 0.988609839372155 0.999930074063124 0.935607086842689 23400/80347/84557/4204 4 0.38063573623495
473 WP3945 TYROBP Causal Network 6/1022 57/4839 0.988988247391084 0.999930074063124 0.935607086842689 54518/718/3071/5996/6696/7133 6 0.436081519221862
474 WP3937 Microglia Pathogen Phagocytosis Pathway 3/1022 36/4839 0.989310274384808 0.999930074063124 0.935607086842689 3071/5336/5881 3 0.337585868498528
475 WP702 Metapathway biotransformation Phase I and II 11/1022 90/4839 0.990437699484362 0.999930074063124 0.935607086842689 57404/1593/51302/2053/2878/2949/11185/7881/79829/55226/26151 11 0.514818014498742
476 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 5/1022 52/4839 0.991808941236611 0.999930074063124 0.935607086842689 2353/4286/4772/7185/7186 5 0.394359714638382
477 WP4674 Head and Neck Squamous Cell Carcinoma 7/1022 66/4839 0.992314718762537 0.999930074063124 0.935607086842689 10000/1017/1019/1978/4893/5563/7048 7 0.43927527761543
478 WP4136 Fibrin Complement Receptor 3 Signaling Pathway 2/1022 30/4839 0.992801390486254 0.999930074063124 0.935607086842689 6347/3569 2 0.265336134453782
479 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 15/1022 117/4839 0.993096492146131 0.999930074063124 0.935607086842689 1978/2194/2308/2932/9020/4215/1326/5563/51422/6196/9252/6319/6567/6517/7067 15 0.542525848472458
480 WP4217 Ebola Virus Pathway on Host 15/1022 118/4839 0.993885846002832 0.999930074063124 0.935607086842689 6868/558/857/30835/10462/5610/2316/2318/2621/2934/3678/3690/388/9021/64601 15 0.537113988488349
481 WP2272 Pathogenic Escherichia coli infection 4/1022 47/4839 0.994390806182559 0.999930074063124 0.935607086842689 25/2534/10381/84617 4 0.344862246995934
482 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway 2/1022 32/4839 0.995269091959466 0.999930074063124 0.935607086842689 22861/114548 2 0.247516339869281
483 WP4329 miRNAs involvement in the immune response in sepsis 2/1022 32/4839 0.995269091959466 0.999930074063124 0.935607086842689 3569/3663 2 0.247516339869281
484 WP3869 Cannabinoid receptor signaling 1/1022 23/4839 0.995791481164406 0.999930074063124 0.935607086842689 5577 1 0.168952007835455
485 WP477 Cytoplasmic Ribosomal Proteins 9/1022 85/4839 0.996761791106334 0.999930074063124 0.935607086842689 9801/6138/6122/6164/6133/6207/6228/6196/6203 9 0.437327895256404
486 WP4532 Intraflagellar transport proteins binding to dynein 1/1022 25/4839 0.997388279639291 0.999930074063124 0.935607086842689 89891 1 0.154791054521711
487 WP710 DNA Damage Response (only ATM dependent) 11/1022 100/4839 0.997554537460786 0.999930074063124 0.935607086842689 25/10000/596/894/8061/2932/4609/4893/5881/7472/7482 11 0.45575078629458
488 WP4352 Ciliary landscape 27/1022 197/4839 0.997555018752146 0.999930074063124 0.935607086842689 25904/51138/10238/9343/54512/3066/128239/25804/10982/55388/4171/4173/4174/4175/4176/84515/4436/4637/5048/10051/2040/79989/7431/89891/7465/10413/51646 27 0.582140112326338
489 WP4205 MET in type 1 papillary renal cell carcinoma 4/1022 52/4839 0.99774780836319 0.999930074063124 0.935607086842689 10000/3082/4893/5906 4 0.308529796987557
490 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 8/1022 82/4839 0.998163678878075 0.999930074063124 0.935607086842689 2353/2534/3569/3708/9020/1326/4772/7431 8 0.399061783677168
491 WP4396 Nonalcoholic fatty liver disease 16/1022 135/4839 0.998441141628455 0.999930074063124 0.935607086842689 10000/637/6347/84701/1346/2932/3569/3570/3953/5465/5563/51422/4092/9021/7186/7381 16 0.4942446163356
492 WP1449 Regulation of toll-like receptor signaling pathway 12/1022 111/4839 0.998712123660994 0.999930074063124 0.935607086842689 10000/695/8727/2353/3569/11213/3663/1326/57161/5347/6696/10771 12 0.446204620462046
493 WP2526 PDGF Pathway 2/1022 39/4839 0.998937671665641 0.999930074063124 0.935607086842689 2353/6722 2 0.200317965023847
494 WP75 Toll-like Receptor Signaling Pathway 6/1022 78/4839 0.999677951800867 0.999930074063124 0.935607086842689 10000/2353/3569/3663/1326/6696 6 0.307168635170604
495 WP4536 Genes related to primary cilium development (based on CRISPR) 8/1022 95/4839 0.999779505063155 0.999930074063124 0.935607086842689 57545/11116/51715/163786/79867/79989/79770/89891 8 0.338252964247659
496 WP111 Electron Transport Chain (OXPHOS system in mitochondria) 4/1022 70/4839 0.999930074063124 0.999930074063124 0.935607086842689 1346/9481/291/7381 4 0.223313686967911

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"set_id","name","GENE.SET","MEAN.ABS.T0","PADOG0","P.MEAN.ABS.T","PVAL"
"WP2023","Cell Differentiation - Index expanded","WP2023",4.65,3.97,0.002,1e-05
"WP2029","Cell Differentiation - Index","WP2029",4.49,3.78,1e-05,1e-05
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation","WP1991",5.77,4.98,0.002,0.001
"WP2355","Corticotropin-releasing hormone signaling pathway","WP2355",2.65,0.539,0.016,0.005
"WP2361","Gastric Cancer Network 1","WP2361",5.83,5.94,0.02,0.012
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells","WP4300",2.98,1.79,0.025,0.013
"WP554","ACE Inhibitor Pathway","WP554",3.32,3.11,0.015,0.017
"WP1602","Nicotine Activity on Dopaminergic Neurons","WP1602",2.95,2.84,0.025,0.022
"WP289","Myometrial Relaxation and Contraction Pathways","WP289",4.39,3.34,0.027,0.023
"WP466","DNA Replication","WP466",7.06,6.95,0.029,0.026
"WP3996","Ethanol effects on histone modifications","WP3996",2.9,2.75,0.028,0.029
"WP2197","Endothelin Pathways","WP2197",2.33,1.79,0.057,0.031
"WP3944","Serotonin and anxiety-related events","WP3944",3.63,2.35,0.024,0.032
"WP4222","Phosphodiesterases in neuronal function","WP4222",3.35,3.29,0.036,0.032
"WP2516","ATM Signaling Pathway","WP2516",3.11,1.92,0.066,0.034
"WP35","G Protein Signaling Pathways","WP35",3.9,3.17,0.058,0.034
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma","WP4337",3.19,1.59,0.045,0.036
"WP4016","DNA IR-damage and cellular response via ATR","WP4016",4.23,3.94,0.047,0.042
"WP179","Cell Cycle","WP179",4.97,4.06,0.057,0.044
"WP2276","Glial Cell Differentiation","WP2276",2.33,2.36,0.033,0.044
"WP4589","Major receptors targeted by epinephrine and norepinephrine","WP4589",2.52,2.36,0.043,0.044
"WP4481","Resistin as a regulator of inflammation","WP4481",0.837,-1.09,0.215,0.045
"WP170","Nuclear Receptors","WP170",2.26,2.09,0.052,0.055
"WP45","G1 to S cell cycle control","WP45",4.7,3.8,0.076,0.055
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway","WP2032",1.21,-0.856,0.161,0.056
"WP4545","Oxysterols derived from cholesterol","WP4545",2.36,2.34,0.048,0.056
"WP247","Small Ligand GPCRs","WP247",2.85,2.86,0.046,0.058
"WP3972","PDGFR-beta pathway","WP3972",0.799,-1.47,0.264,0.059
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM","WP3959",2.85,2.02,0.076,0.06
"WP531","DNA Mismatch Repair","WP531",3.42,3.33,0.06,0.06
"WP236","Adipogenesis","WP236",3.23,2.04,0.071,0.062
"WP2431","Spinal Cord Injury","WP2431",2.99,1.54,0.077,0.063
"WP2446","Retinoblastoma Gene in Cancer","WP2446",6.49,5.76,0.077,0.064
"WP410","Exercise-induced Circadian Regulation","WP410",2.06,2.17,0.043,0.066
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling","WP734",0.96,-0.0811,0.109,0.067
"WP1530","miRNA Regulation of DNA Damage Response","WP1530",2.94,1.56,0.101,0.069
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology","WP4535",0.883,-0.0123,0.165,0.069
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways","WP706",2.09,1.29,0.073,0.069
"WP707","DNA Damage Response","WP707",2.81,1.42,0.105,0.077
"WP516","Hypertrophy Model","WP516",2.58,2.33,0.067,0.079
"WP4760","PKC-gamma calcium signaling pathway in ataxia","WP4760",2.6,2.31,0.071,0.083
"WP206","Fatty Acid Omega Oxidation","WP206",2.59,2.63,0.082,0.086
"WP2332","Interleukin-11 Signaling Pathway","WP2332",-0.0761,-1.89,0.431,0.086
"WP545","Complement Activation","WP545",3.38,3.38,0.086,0.087
"WP1528","Physiological and Pathological Hypertrophy of the Heart","WP1528",1.68,0.0921,0.12,0.088
"WP2363","Gastric Cancer Network 2","WP2363",2.23,2.1,0.105,0.088
"WP4149","White fat cell differentiation","WP4149",2.24,1.72,0.082,0.089
"WP383","Striated Muscle Contraction Pathway","WP383",3.63,3.71,0.09,0.092
"WP2806","Human Complement System","WP2806",3.42,3.25,0.088,0.097
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)","WP2815",1.85,0.685,0.138,0.097
"WP3299","let-7 inhibition of ES cell reprogramming","WP3299",2.08,1.36,0.088,0.098
"WP474","Endochondral Ossification","WP474",2.41,1.81,0.109,0.099
"WP558","Complement and Coagulation Cascades","WP558",3.35,3.36,0.091,0.1
"WP536","Calcium Regulation in the Cardiac Cell","WP536",3.57,3.14,0.112,0.101
"WP2855","Dopaminergic Neurogenesis","WP2855",2.1,1.73,0.118,0.102
"WP2406","Cardiac Progenitor Differentiation","WP2406",2.36,1.51,0.08,0.104
"WP4752","Base Excision Repair","WP4752",1.94,1.95,0.082,0.104
"WP2848","Differentiation Pathway","WP2848",2.55,1.58,0.088,0.107
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition","WP4240",2.93,3.03,0.101,0.107
"WP3893","Development and heterogeneity of the ILC family","WP3893",2.68,2.14,0.069,0.11
"WP2849","Hematopoietic Stem Cell Differentiation","WP2849",2.77,1.98,0.085,0.12
"WP3594","Circadian rhythm related genes","WP3594",1.98,1.21,0.101,0.121
"WP1971","Integrated Cancer Pathway","WP1971",1.86,0.186,0.172,0.123
"WP3591","Sleep regulation","WP3591",2.46,1.3,0.043,0.123
"WP3599","Transcription factor regulation in adipogenesis","WP3599",1.61,0.435,0.103,0.123
"WP34","Ovarian Infertility Genes","WP34",1.46,1.09,0.114,0.126
"WP497","Urea cycle and metabolism of amino groups","WP497",1.96,2,0.094,0.136
"WP727","Monoamine Transport","WP727",1.65,1.24,0.134,0.137
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.","WP3611",1.88,-0.251,0.149,0.138
"WP1423","Ganglio Sphingolipid Metabolism","WP1423",1.56,1.65,0.103,0.148
"WP241","One Carbon Metabolism","WP241",1.69,1.56,0.113,0.149
"WP3947","Serotonin and anxiety","WP3947",2.21,1.06,0.078,0.15
"WP4321","Thermogenesis","WP4321",0.636,-0.11,0.246,0.16
"WP1544","MicroRNAs in cardiomyocyte hypertrophy","WP1544",-0.0823,-1.86,0.536,0.161
"WP1984","Integrated Breast Cancer Pathway","WP1984",0.94,-0.623,0.271,0.161
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement","WP4560",1.37,0.572,0.201,0.161
"WP2038","Regulation of Microtubule Cytoskeleton","WP2038",1.03,0.327,0.214,0.165
"WP3888","VEGFA-VEGFR2 Signaling Pathway","WP3888",0.532,-0.684,0.256,0.166
"WP3995","Prion disease pathway","WP3995",1.14,-0.0857,0.164,0.166
"WP465","Tryptophan metabolism","WP465",1.73,1.76,0.138,0.168
"WP1545","miRNAs involved in DNA damage response","WP1545",0.93,-0.243,0.274,0.169
"WP1434","Osteopontin Signaling","WP1434",0.816,-0.536,0.267,0.173
"WP560","TGF-beta Receptor Signaling","WP560",1.01,-0.319,0.231,0.175
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis","WP2011",1.31,0.766,0.153,0.178
"WP2374","Oncostatin M Signaling Pathway","WP2374",0.0586,-2.25,0.478,0.184
"WP4583","Biomarkers for urea cycle disorders","WP4583",1.47,1.48,0.139,0.184
"WP1601","Fluoropyrimidine Activity","WP1601",1.68,1.64,0.177,0.186
"WP1992","Genes targeted by miRNAs in adipocytes","WP1992",1.64,1.42,0.132,0.187
"WP2879","Farnesoid X Receptor Pathway","WP2879",1.45,1.23,0.162,0.189
"WP4658","Small cell lung cancer","WP4658",0.928,-1.04,0.338,0.19
"WP1541","Energy Metabolism","WP1541",0.838,-0.0844,0.184,0.192
"WP4584","Biomarkers for pyrimidine metabolism disorders","WP4584",1.54,1.52,0.151,0.192
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling","WP3679",1.83,1.63,0.153,0.193
"WP176","Folate Metabolism","WP176",1.85,0.997,0.171,0.197
"WP186","Homologous recombination","WP186",1.35,1.17,0.158,0.201
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation","WP3876",1.04,0.69,0.213,0.203
"WP4224","Purine metabolism and related disorders","WP4224",1.21,1.27,0.152,0.203
"WP3958","GPR40 Pathway","WP3958",1.29,1.09,0.166,0.205
"WP2874","Liver X Receptor Pathway","WP2874",1.23,0.936,0.2,0.206
"WP384","Apoptosis Modulation by HSP70","WP384",1.19,0.15,0.215,0.207
"WP2525","Trans-sulfuration and one carbon metabolism","WP2525",1.44,1.29,0.173,0.212
"WP3584","MECP2 and Associated Rett Syndrome","WP3584",0.977,0.417,0.178,0.212
"WP4698","Vitamin D-sensitive calcium signaling in depression","WP4698",1.38,0.87,0.154,0.218
"WP2064","Neural Crest Differentiation","WP2064",1.36,0.635,0.217,0.221
"WP2059","Alzheimers Disease","WP2059",1.1,0.32,0.239,0.222
"WP3303","RAC1/PAK1/p38/MMP2 Pathway","WP3303",-0.73,-2.6,0.718,0.226
"WP2338","miRNA Biogenesis","WP2338",1,1.06,0.174,0.228
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging","WP4186",0.645,-0.296,0.282,0.23
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling","WP732",0.104,-1.06,0.423,0.236
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS","WP4304",1.35,1.11,0.22,0.237
"WP138","Androgen receptor signaling pathway","WP138",0.225,-0.951,0.367,0.238
"WP3287","Overview of nanoparticle effects","WP3287",1.39,-0.267,0.125,0.246
"WP4482","Vitamin D in inflammatory diseases","WP4482",0.595,-1,0.302,0.247
"WP4493","Cells and Molecules involved in local acute inflammatory response ","WP4493",1.85,1.08,0.18,0.247
"WP4756","Renin Angiotensin Aldosterone System (RAAS)","WP4756",1.07,0.782,0.23,0.25
"WP58","Monoamine GPCRs","WP58",1.11,1.11,0.194,0.255
"WP382","MAPK Signaling Pathway","WP382",0.104,-1.64,0.502,0.256
"WP2881","Estrogen Receptor Pathway","WP2881",0.908,0.348,0.275,0.257
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)","WP4719",1.41,1.34,0.212,0.258
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)","WP2840",1.56,0.723,0.235,0.259
"WP4259","Disorders of Folate Metabolism and Transport","WP4259",1.2,1.05,0.21,0.261
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)","WP2814",1.13,0.548,0.283,0.266
"WP2485","NAD Biosynthesis II (from tryptophan)","WP2485",1.03,1.06,0.222,0.271
"WP322","Osteoblast Signaling","WP322",1.02,0.73,0.248,0.272
"WP98","Prostaglandin Synthesis and Regulation","WP98",1.63,1.53,0.23,0.273
"WP4172","PI3K-Akt Signaling Pathway","WP4172",0.551,-1.47,0.454,0.277
"WP3298","Melatonin metabolism and effects","WP3298",1.23,0.378,0.238,0.28
"WP4022","Pyrimidine metabolism","WP4022",1.02,1.13,0.228,0.284
"WP24","Peptide GPCRs","WP24",1.66,1.64,0.234,0.288
"WP3875","ATR Signaling","WP3875",0.757,0.678,0.217,0.293
"WP428","Wnt Signaling","WP428",0.825,-0.254,0.316,0.293
"WP53","ID signaling pathway","WP53",1.07,0.524,0.238,0.293
"WP2113","Type III interferon signaling","WP2113",0.793,0.14,0.277,0.294
"WP3892","Development of pulmonary dendritic cells and macrophage subsets","WP3892",1.1,0.866,0.275,0.297
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR","WP3414",0.348,-0.354,0.259,0.304
"WP3929","Chemokine signaling pathway","WP3929",-0.0776,-1.73,0.541,0.307
"WP4298","Viral Acute Myocarditis","WP4298",0.599,-1.07,0.349,0.307
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway","WP3670",0.583,0.296,0.257,0.311
"WP4571","Urea cycle and related diseases","WP4571",0.895,0.925,0.253,0.314
"WP3624","Lung fibrosis","WP3624",1.41,0.593,0.242,0.32
"WP4754","IL-18 signaling pathway","WP4754",0.872,-0.42,0.329,0.32
"WP306","Focal Adhesion","WP306",0.454,-1.16,0.441,0.321
"WP4290","Metabolic reprogramming in colon cancer","WP4290",0.805,0.741,0.272,0.328
"WP4666","Hepatitis B infection","WP4666",-0.596,-3.65,0.623,0.328
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway","WP2036",-0.0759,-2.1,0.492,0.335
"WP3640","Imatinib and Chronic Myeloid Leukemia","WP3640",0.852,0.308,0.285,0.338
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia","WP3658",0.272,-0.379,0.401,0.339
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease","WP3668",0.334,-0.252,0.431,0.341
"WP712","Estrogen signaling pathway","WP712",-0.304,-2.52,0.481,0.341
"WP2371","Parkinsons Disease Pathway","WP2371",0.532,-0.00984,0.299,0.343
"WP2636","Common Pathways Underlying Drug Addiction","WP2636",0.0503,-0.992,0.411,0.343
"WP272","Blood Clotting Cascade","WP272",1.08,1.07,0.286,0.347
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ","WP3595",0.271,0.301,0.297,0.347
"WP4008","NO/cGMP/PKG mediated Neuroprotection","WP4008",0.535,-0.545,0.33,0.349
"WP4204","Tumor suppressor activity of SMARCB1","WP4204",0.728,0.551,0.293,0.351
"WP3646","Hepatitis C and Hepatocellular Carcinoma","WP3646",-0.0122,-1.99,0.525,0.355
"WP1455","Serotonin Transporter Activity","WP1455",0.631,0.451,0.33,0.36
"WP4191","Caloric restriction and aging","WP4191",0.297,-0.316,0.436,0.36
"WP364","IL-6 signaling pathway","WP364",-0.45,-2.26,0.616,0.361
"WP167","Eicosanoid Synthesis","WP167",0.955,0.912,0.287,0.362
"WP2895","Differentiation of white and brown adipocyte ","WP2895",0.77,0.605,0.311,0.365
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk","WP3943",-0.127,-0.304,0.51,0.365
"WP4288","MTHFR deficiency","WP4288",0.69,0.334,0.306,0.367
"WP26","Signal Transduction of S1P Receptor","WP26",0.244,-0.254,0.438,0.368
"WP395","IL-4 Signaling Pathway","WP395",-0.389,-2.37,0.609,0.368
"WP3580","Methionine De Novo and Salvage Pathway","WP3580",0.7,0.743,0.287,0.369
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ","WP3849",-0.471,-1.54,0.623,0.369
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)","WP2817",0.349,-0.221,0.408,0.37
"WP4211","Transcriptional cascade regulating adipogenesis","WP4211",0.709,0.6,0.325,0.37
"WP2878","PPAR Alpha Pathway","WP2878",0.462,-0.15,0.343,0.371
"WP4629","Computational Model of Aerobic Glycolysis","WP4629",0.431,0.352,0.32,0.373
"WP4538","Regulatory circuits of the STAT3 signaling pathway","WP4538",0.548,-0.488,0.421,0.374
"WP2858","Ectoderm Differentiation","WP2858",0.883,0.741,0.311,0.377
"WP2267","Synaptic Vesicle Pathway","WP2267",0.64,0.758,0.302,0.378
"WP4753","Nucleotide Excision Repair","WP4753",0.473,0.458,0.288,0.378
"WP262","EBV LMP1 signaling","WP262",-0.316,-1.39,0.543,0.379
"WP1591","Heart Development","WP1591",0.52,0.0985,0.399,0.38
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling","WP1403",-0.414,-1.39,0.55,0.384
"WP107","Translation Factors","WP107",0.211,0.286,0.296,0.386
"WP2795","Cardiac Hypertrophic Response","WP2795",-0.518,-2.11,0.699,0.386
"WP2369","Histone Modifications","WP2369",0.567,0.685,0.288,0.387
"WP3878","ATM Signaling Network in Development and Disease ","WP3878",0.265,-0.229,0.339,0.388
"WP2034","Leptin signaling pathway","WP2034",-1.27,-3.54,0.798,0.389
"WP127","IL-5 Signaling Pathway","WP127",-0.414,-2.82,0.603,0.391
"WP117","GPCRs, Other","WP117",1.03,1.06,0.313,0.392
"WP4225","Pyrimidine metabolism and related diseases","WP4225",0.806,0.755,0.312,0.393
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy","WP2118",0.689,0.523,0.391,0.394
"WP4147","PTF1A related regulatory pathway","WP4147",0.0857,-0.0368,0.438,0.395
"WP3963","Mevalonate pathway","WP3963",0.406,0.427,0.334,0.399
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment","WP4480",0.335,-1.48,0.381,0.4
"WP524","G13 Signaling Pathway","WP524",-0.124,-0.753,0.475,0.4
"WP2507","Nanomaterial induced apoptosis","WP2507",0.469,-0.619,0.296,0.402
"WP1742","TP53 Network","WP1742",0.708,-0.607,0.355,0.404
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome","WP4320",0.241,-0.0357,0.366,0.405
"WP3527","Preimplantation Embryo","WP3527",0.798,0.657,0.31,0.41
"WP411","mRNA Processing","WP411",-0.581,-0.271,0.321,0.412
"WP366","TGF-beta Signaling Pathway","WP366",-0.555,-1.95,0.576,0.413
"WP3941","Oxidative Damage","WP3941",0.391,-0.79,0.422,0.416
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder","WP4539",-0.491,-2.09,0.63,0.42
"WP4685","Melanoma","WP4685",-0.892,-2.88,0.788,0.423
"WP254","Apoptosis","WP254",0.085,-1.38,0.51,0.424
"WP4673","Genes involved in male infertility","WP4673",0.506,0.184,0.361,0.43
"WP3998","Prader-Willi and Angelman Syndrome","WP3998",0.324,-0.0975,0.438,0.431
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1","WP4269",-0.127,-0.576,0.531,0.432
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway","WP2380",-0.697,-2.86,0.648,0.436
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex","WP3657",0.368,-0.356,0.336,0.438
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation","WP4767",-0.0514,-1.01,0.537,0.438
"WP51","Regulation of Actin Cytoskeleton","WP51",-0.342,-1.24,0.577,0.439
"WP136","Phase I biotransformations, non P450","WP136",0.634,0.66,0.362,0.444
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness","WP3301",-0.0361,-0.849,0.506,0.446
"WP3613","Photodynamic therapy-induced unfolded protein response","WP3613",0.459,0.421,0.355,0.448
"WP4462","Platelet-mediated interactions with vascular and circulating cells","WP4462",0.42,-0.0615,0.438,0.452
"WP4507","Molybdenum cofactor (Moco) biosynthesis","WP4507",0.286,0.33,0.356,0.453
"WP3585","Cytosine methylation","WP3585",0.349,0.325,0.35,0.454
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway","WP3932",-0.326,-1.77,0.616,0.454
"WP1946","Cori Cycle","WP1946",0.102,-0.0555,0.394,0.455
"WP231","TNF alpha Signaling Pathway","WP231",-0.619,-2.24,0.639,0.456
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance","WP3672",0.135,-0.288,0.506,0.456
"WP28","Selenium Metabolism and Selenoproteins","WP28",0.625,-0.229,0.315,0.457
"WP2911","miRNA targets in ECM and membrane receptors","WP2911",0.247,0.176,0.43,0.461
"WP2447","Amyotrophic lateral sclerosis (ALS)","WP2447",-0.0765,-1.19,0.464,0.462
"WP2865","IL1 and megakaryocytes in obesity","WP2865",0.45,-0.0274,0.47,0.463
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3","WP4341",0.301,-1.59,0.472,0.464
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma","WP4553",0.165,-0.0706,0.449,0.464
"WP4286","Genotoxicity pathway","WP4286",0.651,0.544,0.39,0.465
"WP4566","Translation inhibitors in chronically activated PDGFRA cells","WP4566",-0.935,-2.53,0.756,0.467
"WP3935","Leptin Insulin Overlap","WP3935",0.027,-0.643,0.532,0.468
"WP698","Glucuronidation","WP698",0.452,0.498,0.382,0.469
"WP3407","FTO Obesity Variant Mechanism","WP3407",0.621,0.509,0.362,0.472
"WP530","Cytokines and Inflammatory Response","WP530",0.695,-0.124,0.392,0.472
"WP3529","Zinc homeostasis","WP3529",0.347,0.443,0.395,0.473
"WP4357","NRF2-ARE regulation","WP4357",0.0647,-0.688,0.5,0.473
"WP15","Selenium Micronutrient Network","WP15",0.667,-0.104,0.384,0.478
"WP2037","Prolactin Signaling Pathway","WP2037",-0.791,-3.34,0.748,0.481
"WP4540","Pathways Regulating Hippo Signaling","WP4540",-0.178,-1.1,0.517,0.482
"WP3940","One carbon metabolism and related pathways","WP3940",0.484,0.339,0.393,0.486
"WP1533","Vitamin B12 Metabolism","WP1533",0.574,-0.398,0.43,0.487
"WP2007","Iron metabolism in placenta","WP2007",0.307,0.365,0.403,0.492
"WP2870","Extracellular vesicle-mediated signaling in recipient cells","WP2870",-0.651,-1.53,0.689,0.492
"WP4657","22q11.2 Deletion Syndrome","WP4657",0.457,0.374,0.42,0.494
"WP2112","IL17 signaling pathway","WP2112",-0.494,-1.87,0.6,0.496
"WP4236","Disorders of the Krebs cycle","WP4236",-0.00205,0.0313,0.402,0.497
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ","WP4495",0.621,-0.679,0.328,0.5
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)","WP2813",-0.0789,-0.737,0.553,0.502
"WP585","Interferon type I signaling pathways","WP585",-0.356,-1.75,0.597,0.505
"WP23","B Cell Receptor Signaling Pathway","WP23",-0.974,-2.76,0.732,0.506
"WP2586","Aryl Hydrocarbon Receptor Netpath","WP2586",-0.351,-1.67,0.597,0.51
"WP3971","Role of Osx and miRNAs in tooth development","WP3971",0.0582,-0.153,0.524,0.514
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation","WP314",-0.0226,-0.943,0.531,0.519
"WP3617","Photodynamic therapy-induced NF-kB survival signaling","WP3617",0.0179,-1.15,0.529,0.52
"WP1772","Apoptosis Modulation and Signaling","WP1772",0.15,-1.22,0.493,0.521
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ","WP4216",-0.574,-2.77,0.697,0.521
"WP4249","Hedgehog Signaling Pathway","WP4249",0.119,-0.206,0.455,0.522
"WP183","Proteasome Degradation","WP183",-0.664,-0.485,0.456,0.523
"WP437","EGF/EGFR Signaling Pathway","WP437",-0.795,-2.62,0.637,0.525
"WP3930","EDA Signalling in Hair Follicle Development","WP3930",0.281,0.259,0.446,0.526
"WP4541","Hippo-Merlin Signaling Dysregulation","WP4541",-0.199,-0.887,0.578,0.526
"WP1539","Angiogenesis","WP1539",-0.525,-1.29,0.653,0.529
"WP4558","Overview of interferons-mediated signaling pathway","WP4558",-0.177,-1.16,0.516,0.529
"WP4312","Rett syndrome causing genes","WP4312",0.164,0.00715,0.431,0.53
"WP4223","Ras Signaling","WP4223",-1.04,-2.61,0.759,0.532
"WP4659","Gastrin Signaling Pathway","WP4659",-1.4,-3.97,0.846,0.532
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases","WP4518",0.105,0.104,0.455,0.533
"WP4262","Breast cancer pathway","WP4262",-0.685,-2.73,0.758,0.541
"WP4331","Neovascularisation processes","WP4331",-0.467,-1.36,0.639,0.542
"WP197","Cholesterol Biosynthesis Pathway","WP197",-0.352,-0.332,0.471,0.543
"WP3630","NAD metabolism, sirtuins and aging","WP3630",0.227,-0.463,0.446,0.545
"WP129","Matrix Metalloproteinases","WP129",0.376,0.364,0.475,0.548
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection","WP3863",-1.01,-2.6,0.662,0.55
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma","WP4336",0.0538,-0.685,0.526,0.556
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway","WP2203",-0.236,-2.45,0.601,0.557
"WP2261","Signaling Pathways in Glioblastoma","WP2261",-1.07,-3.06,0.883,0.558
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism","WP4746",-0.794,-1.94,0.766,0.564
"WP4533","Transcription co-factors SKI and SKIL protein partners","WP4533",-0.0576,-0.161,0.484,0.568
"WP704","Methylation Pathways","WP704",0.118,0.142,0.457,0.57
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein","WP3872",0.255,-0.894,0.468,0.571
"WP477","Cytoplasmic Ribosomal Proteins","WP477",-2.33,-2.18,0.545,0.571
"WP404","Nucleotide Metabolism","WP404",-0.241,-0.264,0.484,0.572
"WP4255","Non-small cell lung cancer","WP4255",-1.17,-3.26,0.876,0.577
"WP408","Oxidative Stress","WP408",0.45,-0.492,0.434,0.58
"WP4263","Pancreatic adenocarcinoma pathway","WP4263",-1.56,-3.77,0.894,0.581
"WP3931","ESC Pluripotency Pathways","WP3931",-0.827,-2.54,0.779,0.583
"WP2328","Allograft Rejection","WP2328",-0.751,-1.2,0.567,0.586
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses","WP1589",-0.0611,-0.302,0.529,0.588
"WP3655","Hypothetical Craniofacial Development Pathway","WP3655",-0.0586,-0.416,0.502,0.588
"WP3596","miR-517 relationship with ARCN1 and USP1","WP3596",-0.025,-0.425,0.469,0.589
"WP4595","Urea cycle and associated pathways","WP4595",-0.0592,-0.0348,0.48,0.595
"WP286","IL-3 Signaling Pathway","WP286",-1.08,-3.01,0.767,0.597
"WP2882","Nuclear Receptors Meta-Pathway","WP2882",0.247,-0.458,0.577,0.597
"WP481","Insulin Signaling","WP481",-1.01,-2.87,0.765,0.598
"WP4148","Splicing factor NOVA regulated synaptic proteins","WP4148",-0.138,-0.183,0.525,0.599
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)","WP4718",-0.168,-0.209,0.517,0.599
"WP3853","ERK Pathway in Huntington's Disease","WP3853",-0.81,-1.66,0.729,0.6
"WP2853","Endoderm Differentiation","WP2853",-0.134,-0.408,0.561,0.601
"WP1531","Vitamin D Metabolism","WP1531",-0.0646,-0.153,0.527,0.604
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B","WP3656",-0.144,-0.676,0.523,0.606
"WP500","Glycogen Synthesis and Degradation","WP500",-0.177,-0.372,0.5,0.607
"WP134","Pentose Phosphate Metabolism","WP134",-0.343,-0.32,0.516,0.608
"WP455","GPCRs, Class A Rhodopsin-like","WP455",0.441,0.497,0.517,0.609
"WP313","Signaling of Hepatocyte Growth Factor Receptor","WP313",-0.945,-2.52,0.822,0.61
"WP4724","Omega-9 FA synthesis","WP4724",-0.054,-0.136,0.513,0.615
"WP3927","BMP Signaling Pathway in Eyelid Development","WP3927",-0.439,-1.19,0.638,0.616
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase","WP678",-0.173,-0.149,0.512,0.616
"WP4792","Purine metabolism","WP4792",-0.233,-0.191,0.52,0.617
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling","WP3850",-0.323,-1.26,0.628,0.618
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer","WP4258",-0.197,-0.925,0.6,0.619
"WP561","Heme Biosynthesis","WP561",-0.132,-0.0448,0.518,0.619
"WP2249","Metastatic brain tumor","WP2249",-0.509,-1.29,0.674,0.623
"WP3874","Canonical and Non-Canonical TGF-B signaling","WP3874",-0.532,-1.21,0.625,0.623
"WP1422","Sphingolipid pathway","WP1422",-0.109,-0.0785,0.552,0.626
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer","WP2291",-0.0748,0.0435,0.519,0.627
"WP3871","Valproic acid pathway","WP3871",-0.337,-0.369,0.578,0.628
"WP2359","Parkin-Ubiquitin Proteasomal System pathway","WP2359",-0.675,-0.616,0.557,0.63
"WP3634","Insulin signalling in human adipocytes (normal condition)","WP3634",-0.588,-1.22,0.687,0.63
"WP3635","Insulin signalling in human adipocytes (diabetic condition)","WP3635",-0.588,-1.22,0.687,0.63
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway","WP2035",-0.966,-2.23,0.771,0.634
"WP673","ErbB Signaling Pathway","WP673",-1.59,-3.89,0.929,0.635
"WP400","p38 MAPK Signaling Pathway","WP400",-0.913,-1.94,0.734,0.636
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities","WP3844",-0.83,-2.26,0.768,0.638
"WP3942","PPAR signaling pathway","WP3942",-0.0627,-0.198,0.577,0.64
"WP2456","HIF1A and PPARG regulation of glycolysis","WP2456",-0.474,-0.597,0.58,0.641
"WP4239","Epithelial to mesenchymal transition in colorectal cancer","WP4239",-1.26,-2.43,0.808,0.641
"WP3644","NAD+ metabolism","WP3644",-0.11,-0.137,0.538,0.643
"WP391","Mitochondrial Gene Expression","WP391",-0.697,-0.897,0.566,0.645
"WP4483","Relationship between inflammation, COX-2 and EGFR","WP4483",-1.23,-2.35,0.838,0.645
"WP3967","miR-509-3p alteration of YAP1/ECM axis","WP3967",-0.318,-0.409,0.571,0.646
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer","WP2864",-0.39,-1.02,0.654,0.648
"WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer","WP2868",-0.778,-1.78,0.701,0.65
"WP304","Kit receptor signaling pathway","WP304",-0.984,-2.9,0.802,0.65
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms","WP4534",-0.642,-1.07,0.693,0.65
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway","WP69",-1.62,-3.57,0.765,0.654
"WP4496","Signal transduction through IL1R","WP4496",-0.555,-2.31,0.677,0.659
"WP311","Synthesis and Degradation of Ketone Bodies","WP311",-0.219,-0.19,0.555,0.661
"WP2875","Constitutive Androstane Receptor Pathway","WP2875",-0.406,-0.836,0.565,0.662
"WP430","Statin Pathway","WP430",-0.133,-0.153,0.587,0.662
"WP3851","TLR4 Signaling and Tolerance","WP3851",-0.497,-1.68,0.621,0.665
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma","WP3651",-1.1,-1.57,0.712,0.668
"WP2290","RalA downstream regulated genes","WP2290",-0.811,-1.37,0.724,0.679
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway","WP3865",-0.964,-1.87,0.723,0.683
"WP4747","Netrin-UNC5B signaling Pathway","WP4747",-0.985,-2.22,0.799,0.683
"WP422","MAPK Cascade","WP422",-1.13,-2.47,0.816,0.684
"WP2583","T-Cell Receptor and Co-stimulatory Signaling","WP2583",-0.744,-1.81,0.637,0.685
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling","WP4141",-0.575,-1.63,0.669,0.685
"WP4521","Glycosylation and related congenital defects","WP4521",-0.644,-0.502,0.574,0.685
"WP619","Type II interferon signaling (IFNG)","WP619",-0.96,-1.44,0.668,0.691
"WP49","IL-2 Signaling Pathway","WP49",-1,-3.02,0.802,0.698
"WP3937","Microglia Pathogen Phagocytosis Pathway","WP3937",-1.49,-2.05,0.73,0.702
"WP2436","Dopamine metabolism","WP2436",-0.325,-0.464,0.641,0.704
"WP2857","Mesodermal Commitment Pathway","WP2857",-0.456,-0.747,0.652,0.708
"WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway","WP3877",-0.357,-1.09,0.629,0.712
"WP2643","Nanoparticle-mediated activation of receptor signaling","WP2643",-1.64,-3.06,0.88,0.713
"WP2637","Structural Pathway of Interleukin 1 (IL-1)","WP2637",-1.06,-2.88,0.74,0.714
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ","WP2916",-0.633,-0.627,0.603,0.716
"WP4564","Neural Crest Cell Migration during Development","WP4564",-0.828,-2.19,0.763,0.716
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing","WP4705",-0.475,-0.425,0.641,0.717
"WP185","Integrin-mediated Cell Adhesion","WP185",-1.45,-2.38,0.826,0.718
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity","WP3969",-0.568,-0.993,0.716,0.718
"WP4271","Vitamin B12 Disorders","WP4271",-0.497,-0.461,0.602,0.718
"WP4297","Thiamine metabolic pathways","WP4297",-0.532,-0.481,0.613,0.718
"WP4210","Tryptophan catabolism leading to NAD+ production","WP4210",-0.224,-0.184,0.604,0.719
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds","WP3664",-0.58,-1.02,0.689,0.72
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders","WP4292",-0.505,-0.561,0.636,0.725
"WP363","Wnt Signaling Pathway (Netpath)","WP363",-1.27,-2.47,0.796,0.726
"WP205","IL-7 Signaling Pathway","WP205",-1.24,-2.91,0.819,0.727
"WP4725","Sphingolipid Metabolism (general overview)","WP4725",-0.28,-0.251,0.631,0.727
"WP195","IL-1 signaling pathway","WP195",-1.55,-3.07,0.874,0.729
"WP3","Phytochemical activity on NRF2 transcriptional activation","WP3",-0.682,-1.16,0.738,0.729
"WP78","TCA Cycle (aka Krebs or citric acid cycle)","WP78",-1.24,-1.21,0.65,0.729
"WP3925","Amino Acid metabolism","WP3925",-0.645,-0.61,0.658,0.73
"WP4523","Classical pathway of steroidogenesis, including diseases","WP4523",-0.511,-0.462,0.635,0.73
"WP22","IL-9 Signaling Pathway","WP22",-1.18,-2.56,0.787,0.732
"WP4586","Metabolism of alpha-linolenic acid","WP4586",-0.432,-0.501,0.635,0.732
"WP1584","Type II diabetes mellitus","WP1584",-0.879,-1.51,0.753,0.735
"WP268","Notch Signaling","WP268",-0.701,-0.816,0.675,0.737
"WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma","WP3593",-0.719,-0.776,0.682,0.737
"WP3981","miRNA regulation of prostate cancer signaling pathways","WP3981",-1.62,-3.53,0.856,0.741
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells","WP4301",-1.34,-1.87,0.789,0.741
"WP1559","TFs Regulate miRNAs related to cardiac hypertrophy","WP1559",-1.12,-1.9,0.796,0.743
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity","WP299",-0.795,-0.903,0.675,0.743
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment","WP4559",-0.63,-1.46,0.695,0.743
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation","WP1425",-0.558,-0.703,0.673,0.748
"WP4562","Canonical NF-KB pathway","WP4562",-1.01,-2.06,0.748,0.749
"WP2876","Pregnane X Receptor pathway","WP2876",-0.632,-1.07,0.675,0.75
"WP3965","Lipid Metabolism Pathway","WP3965",-0.985,-1.44,0.727,0.75
"WP4389","Bile Acids synthesis and enterohepatic circulation ","WP4389",-0.834,-1.22,0.712,0.75
"WP399","Wnt Signaling Pathway and Pluripotency","WP399",-0.763,-1.86,0.758,0.754
"WP229","Irinotecan Pathway","WP229",-0.407,-0.416,0.677,0.755
"WP2333","Trans-sulfuration pathway","WP2333",-0.6,-0.709,0.657,0.756
"WP4742","Ketogenesis and Ketolysis","WP4742",-0.602,-0.603,0.675,0.757
"WP244","Alpha 6 Beta 4 signaling pathway","WP244",-1.71,-2.98,0.869,0.758
"WP288","NLR Proteins","WP288",-1.4,-1.98,0.814,0.759
"WP1424","Globo Sphingolipid Metabolism","WP1424",-0.338,-0.223,0.658,0.761
"WP501","GPCRs, Class C Metabotropic glutamate, pheromone","WP501",-0.626,-0.568,0.692,0.764
"WP61","Notch Signaling Pathway Netpath","WP61",-0.953,-1.88,0.749,0.764
"WP3926","ApoE and miR-146 in inflammation and atherosclerosis","WP3926",-0.57,-1.15,0.667,0.765
"WP4155","Endometrial cancer","WP4155",-1.63,-3.89,0.93,0.765
"WP2873","Aryl Hydrocarbon Receptor Pathway","WP2873",-0.988,-1.62,0.789,0.771
"WP3286","Copper homeostasis","WP3286",-0.877,-1.57,0.777,0.771
"WP4549","Fragile X Syndrome ","WP4549",-1.63,-2.41,0.864,0.771
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling","WP3612",-0.586,-1.6,0.662,0.777
"WP3300","Dual hijack model of Vif in HIV infection","WP3300",-0.745,-0.704,0.683,0.778
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway","WP4136",-1.22,-2.37,0.804,0.779
"WP2324","AGE/RAGE pathway","WP2324",-1.53,-3.55,0.891,0.781
"WP4537","Hippo-Yap signaling pathway","WP4537",-0.513,-0.578,0.684,0.781
"WP2884","NRF2 pathway","WP2884",-0.531,-0.814,0.72,0.783
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)","WP4721",-0.592,-0.595,0.696,0.786
"WP4478","LTF danger signal response pathway","WP4478",-0.44,-1.63,0.663,0.788
"WP4582","Cancer immunotherapy by CTLA4 blockade","WP4582",-1.26,-2.05,0.837,0.789
"WP75","Toll-like Receptor Signaling Pathway","WP75",-1.67,-3.9,0.897,0.789
"WP4018","Pathways in clear cell renal cell carcinoma","WP4018",-1.19,-1.7,0.796,0.796
"WP4726","Sphingolipid Metabolism (integrated pathway)","WP4726",-0.528,-0.497,0.698,0.796
"WP2533","Glycerophospholipid Biosynthetic Pathway","WP2533",-0.899,-1.08,0.757,0.798
"WP4519","Cerebral Organic Acidurias, including diseases","WP4519",-0.617,-0.571,0.716,0.799
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits","WP3678",-0.976,-1.2,0.803,0.8
"WP2828","Bladder Cancer","WP2828",-1.3,-2.7,0.919,0.804
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions","WP4542",-0.709,-1.28,0.701,0.806
"WP4565","Neural Crest Cell Migration in Cancer","WP4565",-1.12,-2.44,0.827,0.806
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway","WP2018",-1.76,-3.7,0.893,0.812
"WP3933","Kennedy pathway from Sphingolipids","WP3933",-0.72,-0.701,0.716,0.812
"WP2854","Gene regulatory network modelling somitogenesis ","WP2854",-0.634,-0.728,0.729,0.816
"WP3934","Leptin and adiponectin","WP3934",-1.12,-1.19,0.744,0.817
"WP4150","Wnt Signaling in Kidney Disease","WP4150",-1.11,-1.66,0.82,0.824
"WP3845","Canonical and Non-canonical Notch signaling","WP3845",-1.1,-1.25,0.785,0.825
"WP4479","Supression of HMGB1 mediated inflammation by THBD","WP4479",-1.37,-2.33,0.795,0.827
"WP2272","Pathogenic Escherichia coli infection","WP2272",-1.14,-1.55,0.777,0.828
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway","WP4206",-1.36,-1.58,0.816,0.829
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)","WP2453",-1.36,-1.37,0.746,0.833
"WP3945","TYROBP Causal Network","WP3945",-1.84,-1.87,0.777,0.833
"WP405","Eukaryotic Transcription Initiation","WP405",-1.45,-1.35,0.744,0.833
"WP2805","exRNA mechanism of action and biogenesis","WP2805",-0.878,-0.846,0.738,0.834
"WP357","Fatty Acid Biosynthesis","WP357",-0.95,-1.05,0.746,0.837
"WP3645","NAD+ biosynthetic pathways","WP3645",-0.84,-0.859,0.749,0.846
"WP47","Hedgehog Signaling Pathway Netpath","WP47",-1.02,-0.992,0.76,0.846
"WP696","Benzo(a)pyrene metabolism","WP696",-1.35,-1.34,0.776,0.846
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression","WP3879",-1.89,-2.73,0.876,0.847
"WP4656","Joubert Syndrome","WP4656",-1.59,-1.67,0.774,0.85
"WP4205","MET in type 1 papillary renal cell carcinoma","WP4205",-2.39,-4.04,0.97,0.854
"WP716","Vitamin A and Carotenoid Metabolism","WP716",-0.918,-0.994,0.805,0.854
"WP4585","Cancer immunotherapy by PD-1 blockade","WP4585",-1.82,-2.42,0.808,0.855
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus","WP4142",-0.927,-0.896,0.789,0.856
"WP100","Glutathione metabolism","WP100",-1.31,-1.39,0.8,0.859
"WP2526","PDGF Pathway","WP2526",-1.99,-3.97,0.927,0.859
"WP3858","Toll-like Receptor Signaling related to MyD88","WP3858",-1.39,-2.15,0.861,0.861
"WP4655","Cytosolic DNA-sensing pathway","WP4655",-1.59,-2.35,0.819,0.861
"WP4522","Metabolic pathway of LDL, HDL and TG, including diseases","WP4522",-0.842,-0.874,0.779,0.863
"WP12","Osteoclast Signaling","WP12",-1.19,-1.41,0.817,0.864
"WP4197","The human immune response to tuberculosis","WP4197",-1.4,-1.84,0.785,0.864
"WP4241","Type 2 papillary renal cell carcinoma","WP4241",-1.25,-1.6,0.837,0.869
"WP4494","Selective expression of chemokine receptors during T-cell polarization","WP4494",-1.58,-1.83,0.804,0.869
"WP80","Nucleotide GPCRs","WP80",-0.764,-0.737,0.781,0.871
"WP4504","Cysteine and methionine catabolism","WP4504",-1.06,-1.12,0.824,0.872
"WP3982","miRNA regulation of p53 pathway in prostate cancer","WP3982",-1.13,-1.89,0.832,0.873
"WP3676","BDNF-TrkB Signaling","WP3676",-1.81,-2.85,0.951,0.874
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS","WP2572",-1.34,-1.85,0.865,0.876
"WP2942","DDX1 as a regulatory component of the Drosha microprocessor","WP2942",-1.18,-1.3,0.78,0.877
"WP615","Senescence and Autophagy in Cancer","WP615",-1.55,-2.97,0.862,0.879
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling","WP3614",-1.12,-1.55,0.845,0.881
"WP4153","Degradation pathway of sphingolipids, including diseases","WP4153",-1.23,-1.17,0.813,0.881
"WP4217","Ebola Virus Pathway on Host","WP4217",-2.39,-3.15,0.899,0.881
"WP581","EPO Receptor Signaling","WP581",-2.1,-3.12,0.941,0.884
"WP438","Non-homologous end joining","WP438",-1.34,-1.33,0.799,0.888
"WP4561","Cell migration and invasion through p75NTR","WP4561",-1.32,-2.09,0.884,0.891
"WP4722","Glycerolipids and Glycerophospholipids","WP4722",-1.12,-1.09,0.817,0.893
"WP106","Alanine and aspartate metabolism","WP106",-1.07,-1.08,0.821,0.895
"WP3413","NOTCH1 regulation of human endothelial cell calcification","WP3413",-1.18,-1.25,0.855,0.898
"WP2513","Nanoparticle triggered regulated necrosis","WP2513",-1.49,-1.72,0.885,0.906
"WP453","Inflammatory Response Pathway","WP453",-1.94,-2.05,0.851,0.906
"WP691","Tamoxifen metabolism","WP691",-1.28,-1.3,0.849,0.906
"WP4723","Omega-3/Omega-6 FA synthesis","WP4723",-1.41,-1.44,0.847,0.907
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)","WP111",-3.38,-3.27,0.864,0.909
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition","WP3859",-1.69,-2.2,0.902,0.91
"WP1449","Regulation of toll-like receptor signaling pathway","WP1449",-2.09,-3.95,0.943,0.911
"WP4159","GABA receptor Signaling","WP4159",-1.34,-1.31,0.835,0.911
"WP2877","Vitamin D Receptor Pathway","WP2877",-1.05,-1.53,0.868,0.912
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation","WP368",-1.56,-1.6,0.856,0.912
"WP143","Fatty Acid Beta Oxidation","WP143",-1.79,-1.81,0.884,0.919
"WP4396","Nonalcoholic fatty liver disease","WP4396",-2.89,-4.23,0.921,0.921
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway","WP1433",-2.32,-2.82,0.916,0.923
"WP3869","Cannabinoid receptor signaling","WP3869",-1.61,-2.34,0.916,0.924
"WP4146","Macrophage markers","WP4146",-1.96,-1.96,0.864,0.925
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways","WP3680",-2.27,-3.55,0.971,0.932
"WP1471","Target Of Rapamycin (TOR) Signaling","WP1471",-2.42,-3,0.932,0.936
"WP534","Glycolysis and Gluconeogenesis","WP534",-2.04,-2.12,0.888,0.939
"WP692","Sulfation Biotransformation Reaction","WP692",-1.77,-1.77,0.897,0.939
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling","WP1982",-1.82,-2.14,0.912,0.943
"WP4313","Ferroptosis","WP4313",-1.81,-1.81,0.92,0.947
"WP4329","miRNAs involvement in the immune response in sepsis","WP4329",-1.84,-3.22,0.91,0.947
"WP325","Triacylglyceride Synthesis","WP325",-1.77,-1.75,0.9,0.949
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway","WP3915",-2.67,-4.13,0.97,0.949
"WP43","Oxidation by Cytochrome P450","WP43",-1.88,-1.83,0.924,0.952
"WP4352","Ciliary landscape","WP4352",-3.04,-2.98,0.927,0.952
"WP4674","Head and Neck Squamous Cell Carcinoma","WP4674",-2.59,-4.28,0.979,0.952
"WP4758","Nephrotic syndrome","WP4758",-2.14,-2.12,0.932,0.962
"WP2509","Nanoparticle triggered autophagic cell death","WP2509",-1.9,-2.29,0.917,0.964
"WP710","DNA Damage Response (only ATM dependent)","WP710",-2.87,-4.92,0.987,0.97
"WP702","Metapathway biotransformation Phase I and II","WP702",-2.54,-2.42,0.937,0.972
"WP697","Estrogen metabolism","WP697",-2.58,-2.61,0.96,0.977
"WP4536","Genes related to primary cilium development (based on CRISPR)","WP4536",-2.87,-2.68,0.937,0.98
"WP4324","Mitochondrial complex I assembly model OXPHOS system","WP4324",-3.86,-3.78,0.96,0.983
"WP4532","Intraflagellar transport proteins binding to dynein","WP4532",-2.93,-2.86,0.961,0.983
"WP623","Oxidative phosphorylation","WP623",-3.56,-3.52,0.953,0.984
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway","WP4577",-3.37,-3.52,0.971,0.991
1 set_id name GENE.SET MEAN.ABS.T0 PADOG0 P.MEAN.ABS.T PVAL
2 WP2023 Cell Differentiation - Index expanded WP2023 4.65 3.97 0.002 1e-05
3 WP2029 Cell Differentiation - Index WP2029 4.49 3.78 1e-05 1e-05
4 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation WP1991 5.77 4.98 0.002 0.001
5 WP2355 Corticotropin-releasing hormone signaling pathway WP2355 2.65 0.539 0.016 0.005
6 WP2361 Gastric Cancer Network 1 WP2361 5.83 5.94 0.02 0.012
7 WP4300 Extracellular vesicles in the crosstalk of cardiac cells WP4300 2.98 1.79 0.025 0.013
8 WP554 ACE Inhibitor Pathway WP554 3.32 3.11 0.015 0.017
9 WP1602 Nicotine Activity on Dopaminergic Neurons WP1602 2.95 2.84 0.025 0.022
10 WP289 Myometrial Relaxation and Contraction Pathways WP289 4.39 3.34 0.027 0.023
11 WP466 DNA Replication WP466 7.06 6.95 0.029 0.026
12 WP3996 Ethanol effects on histone modifications WP3996 2.9 2.75 0.028 0.029
13 WP2197 Endothelin Pathways WP2197 2.33 1.79 0.057 0.031
14 WP3944 Serotonin and anxiety-related events WP3944 3.63 2.35 0.024 0.032
15 WP4222 Phosphodiesterases in neuronal function WP4222 3.35 3.29 0.036 0.032
16 WP2516 ATM Signaling Pathway WP2516 3.11 1.92 0.066 0.034
17 WP35 G Protein Signaling Pathways WP35 3.9 3.17 0.058 0.034
18 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma WP4337 3.19 1.59 0.045 0.036
19 WP4016 DNA IR-damage and cellular response via ATR WP4016 4.23 3.94 0.047 0.042
20 WP179 Cell Cycle WP179 4.97 4.06 0.057 0.044
21 WP2276 Glial Cell Differentiation WP2276 2.33 2.36 0.033 0.044
22 WP4589 Major receptors targeted by epinephrine and norepinephrine WP4589 2.52 2.36 0.043 0.044
23 WP4481 Resistin as a regulator of inflammation WP4481 0.837 -1.09 0.215 0.045
24 WP170 Nuclear Receptors WP170 2.26 2.09 0.052 0.055
25 WP45 G1 to S cell cycle control WP45 4.7 3.8 0.076 0.055
26 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway WP2032 1.21 -0.856 0.161 0.056
27 WP4545 Oxysterols derived from cholesterol WP4545 2.36 2.34 0.048 0.056
28 WP247 Small Ligand GPCRs WP247 2.85 2.86 0.046 0.058
29 WP3972 PDGFR-beta pathway WP3972 0.799 -1.47 0.264 0.059
30 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM WP3959 2.85 2.02 0.076 0.06
31 WP531 DNA Mismatch Repair WP531 3.42 3.33 0.06 0.06
32 WP236 Adipogenesis WP236 3.23 2.04 0.071 0.062
33 WP2431 Spinal Cord Injury WP2431 2.99 1.54 0.077 0.063
34 WP2446 Retinoblastoma Gene in Cancer WP2446 6.49 5.76 0.077 0.064
35 WP410 Exercise-induced Circadian Regulation WP410 2.06 2.17 0.043 0.066
36 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling WP734 0.96 -0.0811 0.109 0.067
37 WP1530 miRNA Regulation of DNA Damage Response WP1530 2.94 1.56 0.101 0.069
38 WP4535 Envelope proteins and their potential roles in EDMD physiopathology WP4535 0.883 -0.0123 0.165 0.069
39 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways WP706 2.09 1.29 0.073 0.069
40 WP707 DNA Damage Response WP707 2.81 1.42 0.105 0.077
41 WP516 Hypertrophy Model WP516 2.58 2.33 0.067 0.079
42 WP4760 PKC-gamma calcium signaling pathway in ataxia WP4760 2.6 2.31 0.071 0.083
43 WP206 Fatty Acid Omega Oxidation WP206 2.59 2.63 0.082 0.086
44 WP2332 Interleukin-11 Signaling Pathway WP2332 -0.0761 -1.89 0.431 0.086
45 WP545 Complement Activation WP545 3.38 3.38 0.086 0.087
46 WP1528 Physiological and Pathological Hypertrophy of the Heart WP1528 1.68 0.0921 0.12 0.088
47 WP2363 Gastric Cancer Network 2 WP2363 2.23 2.1 0.105 0.088
48 WP4149 White fat cell differentiation WP4149 2.24 1.72 0.082 0.089
49 WP383 Striated Muscle Contraction Pathway WP383 3.63 3.71 0.09 0.092
50 WP2806 Human Complement System WP2806 3.42 3.25 0.088 0.097
51 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) WP2815 1.85 0.685 0.138 0.097
52 WP3299 let-7 inhibition of ES cell reprogramming WP3299 2.08 1.36 0.088 0.098
53 WP474 Endochondral Ossification WP474 2.41 1.81 0.109 0.099
54 WP558 Complement and Coagulation Cascades WP558 3.35 3.36 0.091 0.1
55 WP536 Calcium Regulation in the Cardiac Cell WP536 3.57 3.14 0.112 0.101
56 WP2855 Dopaminergic Neurogenesis WP2855 2.1 1.73 0.118 0.102
57 WP2406 Cardiac Progenitor Differentiation WP2406 2.36 1.51 0.08 0.104
58 WP4752 Base Excision Repair WP4752 1.94 1.95 0.082 0.104
59 WP2848 Differentiation Pathway WP2848 2.55 1.58 0.088 0.107
60 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition WP4240 2.93 3.03 0.101 0.107
61 WP3893 Development and heterogeneity of the ILC family WP3893 2.68 2.14 0.069 0.11
62 WP2849 Hematopoietic Stem Cell Differentiation WP2849 2.77 1.98 0.085 0.12
63 WP3594 Circadian rhythm related genes WP3594 1.98 1.21 0.101 0.121
64 WP1971 Integrated Cancer Pathway WP1971 1.86 0.186 0.172 0.123
65 WP3591 Sleep regulation WP3591 2.46 1.3 0.043 0.123
66 WP3599 Transcription factor regulation in adipogenesis WP3599 1.61 0.435 0.103 0.123
67 WP34 Ovarian Infertility Genes WP34 1.46 1.09 0.114 0.126
68 WP497 Urea cycle and metabolism of amino groups WP497 1.96 2 0.094 0.136
69 WP727 Monoamine Transport WP727 1.65 1.24 0.134 0.137
70 WP3611 Photodynamic therapy-induced AP-1 survival signaling. WP3611 1.88 -0.251 0.149 0.138
71 WP1423 Ganglio Sphingolipid Metabolism WP1423 1.56 1.65 0.103 0.148
72 WP241 One Carbon Metabolism WP241 1.69 1.56 0.113 0.149
73 WP3947 Serotonin and anxiety WP3947 2.21 1.06 0.078 0.15
74 WP4321 Thermogenesis WP4321 0.636 -0.11 0.246 0.16
75 WP1544 MicroRNAs in cardiomyocyte hypertrophy WP1544 -0.0823 -1.86 0.536 0.161
76 WP1984 Integrated Breast Cancer Pathway WP1984 0.94 -0.623 0.271 0.161
77 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement WP4560 1.37 0.572 0.201 0.161
78 WP2038 Regulation of Microtubule Cytoskeleton WP2038 1.03 0.327 0.214 0.165
79 WP3888 VEGFA-VEGFR2 Signaling Pathway WP3888 0.532 -0.684 0.256 0.166
80 WP3995 Prion disease pathway WP3995 1.14 -0.0857 0.164 0.166
81 WP465 Tryptophan metabolism WP465 1.73 1.76 0.138 0.168
82 WP1545 miRNAs involved in DNA damage response WP1545 0.93 -0.243 0.274 0.169
83 WP1434 Osteopontin Signaling WP1434 0.816 -0.536 0.267 0.173
84 WP560 TGF-beta Receptor Signaling WP560 1.01 -0.319 0.231 0.175
85 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis WP2011 1.31 0.766 0.153 0.178
86 WP2374 Oncostatin M Signaling Pathway WP2374 0.0586 -2.25 0.478 0.184
87 WP4583 Biomarkers for urea cycle disorders WP4583 1.47 1.48 0.139 0.184
88 WP1601 Fluoropyrimidine Activity WP1601 1.68 1.64 0.177 0.186
89 WP1992 Genes targeted by miRNAs in adipocytes WP1992 1.64 1.42 0.132 0.187
90 WP2879 Farnesoid X Receptor Pathway WP2879 1.45 1.23 0.162 0.189
91 WP4658 Small cell lung cancer WP4658 0.928 -1.04 0.338 0.19
92 WP1541 Energy Metabolism WP1541 0.838 -0.0844 0.184 0.192
93 WP4584 Biomarkers for pyrimidine metabolism disorders WP4584 1.54 1.52 0.151 0.192
94 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling WP3679 1.83 1.63 0.153 0.193
95 WP176 Folate Metabolism WP176 1.85 0.997 0.171 0.197
96 WP186 Homologous recombination WP186 1.35 1.17 0.158 0.201
97 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation WP3876 1.04 0.69 0.213 0.203
98 WP4224 Purine metabolism and related disorders WP4224 1.21 1.27 0.152 0.203
99 WP3958 GPR40 Pathway WP3958 1.29 1.09 0.166 0.205
100 WP2874 Liver X Receptor Pathway WP2874 1.23 0.936 0.2 0.206
101 WP384 Apoptosis Modulation by HSP70 WP384 1.19 0.15 0.215 0.207
102 WP2525 Trans-sulfuration and one carbon metabolism WP2525 1.44 1.29 0.173 0.212
103 WP3584 MECP2 and Associated Rett Syndrome WP3584 0.977 0.417 0.178 0.212
104 WP4698 Vitamin D-sensitive calcium signaling in depression WP4698 1.38 0.87 0.154 0.218
105 WP2064 Neural Crest Differentiation WP2064 1.36 0.635 0.217 0.221
106 WP2059 Alzheimers Disease WP2059 1.1 0.32 0.239 0.222
107 WP3303 RAC1/PAK1/p38/MMP2 Pathway WP3303 -0.73 -2.6 0.718 0.226
108 WP2338 miRNA Biogenesis WP2338 1 1.06 0.174 0.228
109 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging WP4186 0.645 -0.296 0.282 0.23
110 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling WP732 0.104 -1.06 0.423 0.236
111 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS WP4304 1.35 1.11 0.22 0.237
112 WP138 Androgen receptor signaling pathway WP138 0.225 -0.951 0.367 0.238
113 WP3287 Overview of nanoparticle effects WP3287 1.39 -0.267 0.125 0.246
114 WP4482 Vitamin D in inflammatory diseases WP4482 0.595 -1 0.302 0.247
115 WP4493 Cells and Molecules involved in local acute inflammatory response WP4493 1.85 1.08 0.18 0.247
116 WP4756 Renin Angiotensin Aldosterone System (RAAS) WP4756 1.07 0.782 0.23 0.25
117 WP58 Monoamine GPCRs WP58 1.11 1.11 0.194 0.255
118 WP382 MAPK Signaling Pathway WP382 0.104 -1.64 0.502 0.256
119 WP2881 Estrogen Receptor Pathway WP2881 0.908 0.348 0.275 0.257
120 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) WP4719 1.41 1.34 0.212 0.258
121 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) WP2840 1.56 0.723 0.235 0.259
122 WP4259 Disorders of Folate Metabolism and Transport WP4259 1.2 1.05 0.21 0.261
123 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) WP2814 1.13 0.548 0.283 0.266
124 WP2485 NAD Biosynthesis II (from tryptophan) WP2485 1.03 1.06 0.222 0.271
125 WP322 Osteoblast Signaling WP322 1.02 0.73 0.248 0.272
126 WP98 Prostaglandin Synthesis and Regulation WP98 1.63 1.53 0.23 0.273
127 WP4172 PI3K-Akt Signaling Pathway WP4172 0.551 -1.47 0.454 0.277
128 WP3298 Melatonin metabolism and effects WP3298 1.23 0.378 0.238 0.28
129 WP4022 Pyrimidine metabolism WP4022 1.02 1.13 0.228 0.284
130 WP24 Peptide GPCRs WP24 1.66 1.64 0.234 0.288
131 WP3875 ATR Signaling WP3875 0.757 0.678 0.217 0.293
132 WP428 Wnt Signaling WP428 0.825 -0.254 0.316 0.293
133 WP53 ID signaling pathway WP53 1.07 0.524 0.238 0.293
134 WP2113 Type III interferon signaling WP2113 0.793 0.14 0.277 0.294
135 WP3892 Development of pulmonary dendritic cells and macrophage subsets WP3892 1.1 0.866 0.275 0.297
136 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR WP3414 0.348 -0.354 0.259 0.304
137 WP3929 Chemokine signaling pathway WP3929 -0.0776 -1.73 0.541 0.307
138 WP4298 Viral Acute Myocarditis WP4298 0.599 -1.07 0.349 0.307
139 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway WP3670 0.583 0.296 0.257 0.311
140 WP4571 Urea cycle and related diseases WP4571 0.895 0.925 0.253 0.314
141 WP3624 Lung fibrosis WP3624 1.41 0.593 0.242 0.32
142 WP4754 IL-18 signaling pathway WP4754 0.872 -0.42 0.329 0.32
143 WP306 Focal Adhesion WP306 0.454 -1.16 0.441 0.321
144 WP4290 Metabolic reprogramming in colon cancer WP4290 0.805 0.741 0.272 0.328
145 WP4666 Hepatitis B infection WP4666 -0.596 -3.65 0.623 0.328
146 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway WP2036 -0.0759 -2.1 0.492 0.335
147 WP3640 Imatinib and Chronic Myeloid Leukemia WP3640 0.852 0.308 0.285 0.338
148 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia WP3658 0.272 -0.379 0.401 0.339
149 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease WP3668 0.334 -0.252 0.431 0.341
150 WP712 Estrogen signaling pathway WP712 -0.304 -2.52 0.481 0.341
151 WP2371 Parkinsons Disease Pathway WP2371 0.532 -0.00984 0.299 0.343
152 WP2636 Common Pathways Underlying Drug Addiction WP2636 0.0503 -0.992 0.411 0.343
153 WP272 Blood Clotting Cascade WP272 1.08 1.07 0.286 0.347
154 WP3595 mir-124 predicted interactions with cell cycle and differentiation WP3595 0.271 0.301 0.297 0.347
155 WP4008 NO/cGMP/PKG mediated Neuroprotection WP4008 0.535 -0.545 0.33 0.349
156 WP4204 Tumor suppressor activity of SMARCB1 WP4204 0.728 0.551 0.293 0.351
157 WP3646 Hepatitis C and Hepatocellular Carcinoma WP3646 -0.0122 -1.99 0.525 0.355
158 WP1455 Serotonin Transporter Activity WP1455 0.631 0.451 0.33 0.36
159 WP4191 Caloric restriction and aging WP4191 0.297 -0.316 0.436 0.36
160 WP364 IL-6 signaling pathway WP364 -0.45 -2.26 0.616 0.361
161 WP167 Eicosanoid Synthesis WP167 0.955 0.912 0.287 0.362
162 WP2895 Differentiation of white and brown adipocyte WP2895 0.77 0.605 0.311 0.365
163 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk WP3943 -0.127 -0.304 0.51 0.365
164 WP4288 MTHFR deficiency WP4288 0.69 0.334 0.306 0.367
165 WP26 Signal Transduction of S1P Receptor WP26 0.244 -0.254 0.438 0.368
166 WP395 IL-4 Signaling Pathway WP395 -0.389 -2.37 0.609 0.368
167 WP3580 Methionine De Novo and Salvage Pathway WP3580 0.7 0.743 0.287 0.369
168 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ WP3849 -0.471 -1.54 0.623 0.369
169 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) WP2817 0.349 -0.221 0.408 0.37
170 WP4211 Transcriptional cascade regulating adipogenesis WP4211 0.709 0.6 0.325 0.37
171 WP2878 PPAR Alpha Pathway WP2878 0.462 -0.15 0.343 0.371
172 WP4629 Computational Model of Aerobic Glycolysis WP4629 0.431 0.352 0.32 0.373
173 WP4538 Regulatory circuits of the STAT3 signaling pathway WP4538 0.548 -0.488 0.421 0.374
174 WP2858 Ectoderm Differentiation WP2858 0.883 0.741 0.311 0.377
175 WP2267 Synaptic Vesicle Pathway WP2267 0.64 0.758 0.302 0.378
176 WP4753 Nucleotide Excision Repair WP4753 0.473 0.458 0.288 0.378
177 WP262 EBV LMP1 signaling WP262 -0.316 -1.39 0.543 0.379
178 WP1591 Heart Development WP1591 0.52 0.0985 0.399 0.38
179 WP1403 AMP-activated Protein Kinase (AMPK) Signaling WP1403 -0.414 -1.39 0.55 0.384
180 WP107 Translation Factors WP107 0.211 0.286 0.296 0.386
181 WP2795 Cardiac Hypertrophic Response WP2795 -0.518 -2.11 0.699 0.386
182 WP2369 Histone Modifications WP2369 0.567 0.685 0.288 0.387
183 WP3878 ATM Signaling Network in Development and Disease WP3878 0.265 -0.229 0.339 0.388
184 WP2034 Leptin signaling pathway WP2034 -1.27 -3.54 0.798 0.389
185 WP127 IL-5 Signaling Pathway WP127 -0.414 -2.82 0.603 0.391
186 WP117 GPCRs, Other WP117 1.03 1.06 0.313 0.392
187 WP4225 Pyrimidine metabolism and related diseases WP4225 0.806 0.755 0.312 0.393
188 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy WP2118 0.689 0.523 0.391 0.394
189 WP4147 PTF1A related regulatory pathway WP4147 0.0857 -0.0368 0.438 0.395
190 WP3963 Mevalonate pathway WP3963 0.406 0.427 0.334 0.399
191 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment WP4480 0.335 -1.48 0.381 0.4
192 WP524 G13 Signaling Pathway WP524 -0.124 -0.753 0.475 0.4
193 WP2507 Nanomaterial induced apoptosis WP2507 0.469 -0.619 0.296 0.402
194 WP1742 TP53 Network WP1742 0.708 -0.607 0.355 0.404
195 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome WP4320 0.241 -0.0357 0.366 0.405
196 WP3527 Preimplantation Embryo WP3527 0.798 0.657 0.31 0.41
197 WP411 mRNA Processing WP411 -0.581 -0.271 0.321 0.412
198 WP366 TGF-beta Signaling Pathway WP366 -0.555 -1.95 0.576 0.413
199 WP3941 Oxidative Damage WP3941 0.391 -0.79 0.422 0.416
200 WP4539 Synaptic signaling pathways associated with autism spectrum disorder WP4539 -0.491 -2.09 0.63 0.42
201 WP4685 Melanoma WP4685 -0.892 -2.88 0.788 0.423
202 WP254 Apoptosis WP254 0.085 -1.38 0.51 0.424
203 WP4673 Genes involved in male infertility WP4673 0.506 0.184 0.361 0.43
204 WP3998 Prader-Willi and Angelman Syndrome WP3998 0.324 -0.0975 0.438 0.431
205 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 WP4269 -0.127 -0.576 0.531 0.432
206 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway WP2380 -0.697 -2.86 0.648 0.436
207 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex WP3657 0.368 -0.356 0.336 0.438
208 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation WP4767 -0.0514 -1.01 0.537 0.438
209 WP51 Regulation of Actin Cytoskeleton WP51 -0.342 -1.24 0.577 0.439
210 WP136 Phase I biotransformations, non P450 WP136 0.634 0.66 0.362 0.444
211 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness WP3301 -0.0361 -0.849 0.506 0.446
212 WP3613 Photodynamic therapy-induced unfolded protein response WP3613 0.459 0.421 0.355 0.448
213 WP4462 Platelet-mediated interactions with vascular and circulating cells WP4462 0.42 -0.0615 0.438 0.452
214 WP4507 Molybdenum cofactor (Moco) biosynthesis WP4507 0.286 0.33 0.356 0.453
215 WP3585 Cytosine methylation WP3585 0.349 0.325 0.35 0.454
216 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway WP3932 -0.326 -1.77 0.616 0.454
217 WP1946 Cori Cycle WP1946 0.102 -0.0555 0.394 0.455
218 WP231 TNF alpha Signaling Pathway WP231 -0.619 -2.24 0.639 0.456
219 WP3672 LncRNA-mediated mechanisms of therapeutic resistance WP3672 0.135 -0.288 0.506 0.456
220 WP28 Selenium Metabolism and Selenoproteins WP28 0.625 -0.229 0.315 0.457
221 WP2911 miRNA targets in ECM and membrane receptors WP2911 0.247 0.176 0.43 0.461
222 WP2447 Amyotrophic lateral sclerosis (ALS) WP2447 -0.0765 -1.19 0.464 0.462
223 WP2865 IL1 and megakaryocytes in obesity WP2865 0.45 -0.0274 0.47 0.463
224 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 WP4341 0.301 -1.59 0.472 0.464
225 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma WP4553 0.165 -0.0706 0.449 0.464
226 WP4286 Genotoxicity pathway WP4286 0.651 0.544 0.39 0.465
227 WP4566 Translation inhibitors in chronically activated PDGFRA cells WP4566 -0.935 -2.53 0.756 0.467
228 WP3935 Leptin Insulin Overlap WP3935 0.027 -0.643 0.532 0.468
229 WP698 Glucuronidation WP698 0.452 0.498 0.382 0.469
230 WP3407 FTO Obesity Variant Mechanism WP3407 0.621 0.509 0.362 0.472
231 WP530 Cytokines and Inflammatory Response WP530 0.695 -0.124 0.392 0.472
232 WP3529 Zinc homeostasis WP3529 0.347 0.443 0.395 0.473
233 WP4357 NRF2-ARE regulation WP4357 0.0647 -0.688 0.5 0.473
234 WP15 Selenium Micronutrient Network WP15 0.667 -0.104 0.384 0.478
235 WP2037 Prolactin Signaling Pathway WP2037 -0.791 -3.34 0.748 0.481
236 WP4540 Pathways Regulating Hippo Signaling WP4540 -0.178 -1.1 0.517 0.482
237 WP3940 One carbon metabolism and related pathways WP3940 0.484 0.339 0.393 0.486
238 WP1533 Vitamin B12 Metabolism WP1533 0.574 -0.398 0.43 0.487
239 WP2007 Iron metabolism in placenta WP2007 0.307 0.365 0.403 0.492
240 WP2870 Extracellular vesicle-mediated signaling in recipient cells WP2870 -0.651 -1.53 0.689 0.492
241 WP4657 22q11.2 Deletion Syndrome WP4657 0.457 0.374 0.42 0.494
242 WP2112 IL17 signaling pathway WP2112 -0.494 -1.87 0.6 0.496
243 WP4236 Disorders of the Krebs cycle WP4236 -0.00205 0.0313 0.402 0.497
244 WP4495 IL-10 Anti-inflammatory Signaling Pathway WP4495 0.621 -0.679 0.328 0.5
245 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) WP2813 -0.0789 -0.737 0.553 0.502
246 WP585 Interferon type I signaling pathways WP585 -0.356 -1.75 0.597 0.505
247 WP23 B Cell Receptor Signaling Pathway WP23 -0.974 -2.76 0.732 0.506
248 WP2586 Aryl Hydrocarbon Receptor Netpath WP2586 -0.351 -1.67 0.597 0.51
249 WP3971 Role of Osx and miRNAs in tooth development WP3971 0.0582 -0.153 0.524 0.514
250 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation WP314 -0.0226 -0.943 0.531 0.519
251 WP3617 Photodynamic therapy-induced NF-kB survival signaling WP3617 0.0179 -1.15 0.529 0.52
252 WP1772 Apoptosis Modulation and Signaling WP1772 0.15 -1.22 0.493 0.521
253 WP4216 Chromosomal and microsatellite instability in colorectal cancer WP4216 -0.574 -2.77 0.697 0.521
254 WP4249 Hedgehog Signaling Pathway WP4249 0.119 -0.206 0.455 0.522
255 WP183 Proteasome Degradation WP183 -0.664 -0.485 0.456 0.523
256 WP437 EGF/EGFR Signaling Pathway WP437 -0.795 -2.62 0.637 0.525
257 WP3930 EDA Signalling in Hair Follicle Development WP3930 0.281 0.259 0.446 0.526
258 WP4541 Hippo-Merlin Signaling Dysregulation WP4541 -0.199 -0.887 0.578 0.526
259 WP1539 Angiogenesis WP1539 -0.525 -1.29 0.653 0.529
260 WP4558 Overview of interferons-mediated signaling pathway WP4558 -0.177 -1.16 0.516 0.529
261 WP4312 Rett syndrome causing genes WP4312 0.164 0.00715 0.431 0.53
262 WP4223 Ras Signaling WP4223 -1.04 -2.61 0.759 0.532
263 WP4659 Gastrin Signaling Pathway WP4659 -1.4 -3.97 0.846 0.532
264 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases WP4518 0.105 0.104 0.455 0.533
265 WP4262 Breast cancer pathway WP4262 -0.685 -2.73 0.758 0.541
266 WP4331 Neovascularisation processes WP4331 -0.467 -1.36 0.639 0.542
267 WP197 Cholesterol Biosynthesis Pathway WP197 -0.352 -0.332 0.471 0.543
268 WP3630 NAD metabolism, sirtuins and aging WP3630 0.227 -0.463 0.446 0.545
269 WP129 Matrix Metalloproteinases WP129 0.376 0.364 0.475 0.548
270 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection WP3863 -1.01 -2.6 0.662 0.55
271 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma WP4336 0.0538 -0.685 0.526 0.556
272 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway WP2203 -0.236 -2.45 0.601 0.557
273 WP2261 Signaling Pathways in Glioblastoma WP2261 -1.07 -3.06 0.883 0.558
274 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism WP4746 -0.794 -1.94 0.766 0.564
275 WP4533 Transcription co-factors SKI and SKIL protein partners WP4533 -0.0576 -0.161 0.484 0.568
276 WP704 Methylation Pathways WP704 0.118 0.142 0.457 0.57
277 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein WP3872 0.255 -0.894 0.468 0.571
278 WP477 Cytoplasmic Ribosomal Proteins WP477 -2.33 -2.18 0.545 0.571
279 WP404 Nucleotide Metabolism WP404 -0.241 -0.264 0.484 0.572
280 WP4255 Non-small cell lung cancer WP4255 -1.17 -3.26 0.876 0.577
281 WP408 Oxidative Stress WP408 0.45 -0.492 0.434 0.58
282 WP4263 Pancreatic adenocarcinoma pathway WP4263 -1.56 -3.77 0.894 0.581
283 WP3931 ESC Pluripotency Pathways WP3931 -0.827 -2.54 0.779 0.583
284 WP2328 Allograft Rejection WP2328 -0.751 -1.2 0.567 0.586
285 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses WP1589 -0.0611 -0.302 0.529 0.588
286 WP3655 Hypothetical Craniofacial Development Pathway WP3655 -0.0586 -0.416 0.502 0.588
287 WP3596 miR-517 relationship with ARCN1 and USP1 WP3596 -0.025 -0.425 0.469 0.589
288 WP4595 Urea cycle and associated pathways WP4595 -0.0592 -0.0348 0.48 0.595
289 WP286 IL-3 Signaling Pathway WP286 -1.08 -3.01 0.767 0.597
290 WP2882 Nuclear Receptors Meta-Pathway WP2882 0.247 -0.458 0.577 0.597
291 WP481 Insulin Signaling WP481 -1.01 -2.87 0.765 0.598
292 WP4148 Splicing factor NOVA regulated synaptic proteins WP4148 -0.138 -0.183 0.525 0.599
293 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) WP4718 -0.168 -0.209 0.517 0.599
294 WP3853 ERK Pathway in Huntington's Disease WP3853 -0.81 -1.66 0.729 0.6
295 WP2853 Endoderm Differentiation WP2853 -0.134 -0.408 0.561 0.601
296 WP1531 Vitamin D Metabolism WP1531 -0.0646 -0.153 0.527 0.604
297 WP3656 Interleukin-1 Induced Activation of NF-kappa-B WP3656 -0.144 -0.676 0.523 0.606
298 WP500 Glycogen Synthesis and Degradation WP500 -0.177 -0.372 0.5 0.607
299 WP134 Pentose Phosphate Metabolism WP134 -0.343 -0.32 0.516 0.608
300 WP455 GPCRs, Class A Rhodopsin-like WP455 0.441 0.497 0.517 0.609
301 WP313 Signaling of Hepatocyte Growth Factor Receptor WP313 -0.945 -2.52 0.822 0.61
302 WP4724 Omega-9 FA synthesis WP4724 -0.054 -0.136 0.513 0.615
303 WP3927 BMP Signaling Pathway in Eyelid Development WP3927 -0.439 -1.19 0.638 0.616
304 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase WP678 -0.173 -0.149 0.512 0.616
305 WP4792 Purine metabolism WP4792 -0.233 -0.191 0.52 0.617
306 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling WP3850 -0.323 -1.26 0.628 0.618
307 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer WP4258 -0.197 -0.925 0.6 0.619
308 WP561 Heme Biosynthesis WP561 -0.132 -0.0448 0.518 0.619
309 WP2249 Metastatic brain tumor WP2249 -0.509 -1.29 0.674 0.623
310 WP3874 Canonical and Non-Canonical TGF-B signaling WP3874 -0.532 -1.21 0.625 0.623
311 WP1422 Sphingolipid pathway WP1422 -0.109 -0.0785 0.552 0.626
312 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer WP2291 -0.0748 0.0435 0.519 0.627
313 WP3871 Valproic acid pathway WP3871 -0.337 -0.369 0.578 0.628
314 WP2359 Parkin-Ubiquitin Proteasomal System pathway WP2359 -0.675 -0.616 0.557 0.63
315 WP3634 Insulin signalling in human adipocytes (normal condition) WP3634 -0.588 -1.22 0.687 0.63
316 WP3635 Insulin signalling in human adipocytes (diabetic condition) WP3635 -0.588 -1.22 0.687 0.63
317 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway WP2035 -0.966 -2.23 0.771 0.634
318 WP673 ErbB Signaling Pathway WP673 -1.59 -3.89 0.929 0.635
319 WP400 p38 MAPK Signaling Pathway WP400 -0.913 -1.94 0.734 0.636
320 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities WP3844 -0.83 -2.26 0.768 0.638
321 WP3942 PPAR signaling pathway WP3942 -0.0627 -0.198 0.577 0.64
322 WP2456 HIF1A and PPARG regulation of glycolysis WP2456 -0.474 -0.597 0.58 0.641
323 WP4239 Epithelial to mesenchymal transition in colorectal cancer WP4239 -1.26 -2.43 0.808 0.641
324 WP3644 NAD+ metabolism WP3644 -0.11 -0.137 0.538 0.643
325 WP391 Mitochondrial Gene Expression WP391 -0.697 -0.897 0.566 0.645
326 WP4483 Relationship between inflammation, COX-2 and EGFR WP4483 -1.23 -2.35 0.838 0.645
327 WP3967 miR-509-3p alteration of YAP1/ECM axis WP3967 -0.318 -0.409 0.571 0.646
328 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer WP2864 -0.39 -1.02 0.654 0.648
329 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer WP2868 -0.778 -1.78 0.701 0.65
330 WP304 Kit receptor signaling pathway WP304 -0.984 -2.9 0.802 0.65
331 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms WP4534 -0.642 -1.07 0.693 0.65
332 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway WP69 -1.62 -3.57 0.765 0.654
333 WP4496 Signal transduction through IL1R WP4496 -0.555 -2.31 0.677 0.659
334 WP311 Synthesis and Degradation of Ketone Bodies WP311 -0.219 -0.19 0.555 0.661
335 WP2875 Constitutive Androstane Receptor Pathway WP2875 -0.406 -0.836 0.565 0.662
336 WP430 Statin Pathway WP430 -0.133 -0.153 0.587 0.662
337 WP3851 TLR4 Signaling and Tolerance WP3851 -0.497 -1.68 0.621 0.665
338 WP3651 Pathways Affected in Adenoid Cystic Carcinoma WP3651 -1.1 -1.57 0.712 0.668
339 WP2290 RalA downstream regulated genes WP2290 -0.811 -1.37 0.724 0.679
340 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway WP3865 -0.964 -1.87 0.723 0.683
341 WP4747 Netrin-UNC5B signaling Pathway WP4747 -0.985 -2.22 0.799 0.683
342 WP422 MAPK Cascade WP422 -1.13 -2.47 0.816 0.684
343 WP2583 T-Cell Receptor and Co-stimulatory Signaling WP2583 -0.744 -1.81 0.637 0.685
344 WP4141 PI3K/AKT/mTOR - VitD3 Signalling WP4141 -0.575 -1.63 0.669 0.685
345 WP4521 Glycosylation and related congenital defects WP4521 -0.644 -0.502 0.574 0.685
346 WP619 Type II interferon signaling (IFNG) WP619 -0.96 -1.44 0.668 0.691
347 WP49 IL-2 Signaling Pathway WP49 -1 -3.02 0.802 0.698
348 WP3937 Microglia Pathogen Phagocytosis Pathway WP3937 -1.49 -2.05 0.73 0.702
349 WP2436 Dopamine metabolism WP2436 -0.325 -0.464 0.641 0.704
350 WP2857 Mesodermal Commitment Pathway WP2857 -0.456 -0.747 0.652 0.708
351 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway WP3877 -0.357 -1.09 0.629 0.712
352 WP2643 Nanoparticle-mediated activation of receptor signaling WP2643 -1.64 -3.06 0.88 0.713
353 WP2637 Structural Pathway of Interleukin 1 (IL-1) WP2637 -1.06 -2.88 0.74 0.714
354 WP2916 Interactome of polycomb repressive complex 2 (PRC2) WP2916 -0.633 -0.627 0.603 0.716
355 WP4564 Neural Crest Cell Migration during Development WP4564 -0.828 -2.19 0.763 0.716
356 WP4705 Pathways of nucleic acid metabolism and innate immune sensing WP4705 -0.475 -0.425 0.641 0.717
357 WP185 Integrin-mediated Cell Adhesion WP185 -1.45 -2.38 0.826 0.718
358 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity WP3969 -0.568 -0.993 0.716 0.718
359 WP4271 Vitamin B12 Disorders WP4271 -0.497 -0.461 0.602 0.718
360 WP4297 Thiamine metabolic pathways WP4297 -0.532 -0.481 0.613 0.718
361 WP4210 Tryptophan catabolism leading to NAD+ production WP4210 -0.224 -0.184 0.604 0.719
362 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds WP3664 -0.58 -1.02 0.689 0.72
363 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders WP4292 -0.505 -0.561 0.636 0.725
364 WP363 Wnt Signaling Pathway (Netpath) WP363 -1.27 -2.47 0.796 0.726
365 WP205 IL-7 Signaling Pathway WP205 -1.24 -2.91 0.819 0.727
366 WP4725 Sphingolipid Metabolism (general overview) WP4725 -0.28 -0.251 0.631 0.727
367 WP195 IL-1 signaling pathway WP195 -1.55 -3.07 0.874 0.729
368 WP3 Phytochemical activity on NRF2 transcriptional activation WP3 -0.682 -1.16 0.738 0.729
369 WP78 TCA Cycle (aka Krebs or citric acid cycle) WP78 -1.24 -1.21 0.65 0.729
370 WP3925 Amino Acid metabolism WP3925 -0.645 -0.61 0.658 0.73
371 WP4523 Classical pathway of steroidogenesis, including diseases WP4523 -0.511 -0.462 0.635 0.73
372 WP22 IL-9 Signaling Pathway WP22 -1.18 -2.56 0.787 0.732
373 WP4586 Metabolism of alpha-linolenic acid WP4586 -0.432 -0.501 0.635 0.732
374 WP1584 Type II diabetes mellitus WP1584 -0.879 -1.51 0.753 0.735
375 WP268 Notch Signaling WP268 -0.701 -0.816 0.675 0.737
376 WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma WP3593 -0.719 -0.776 0.682 0.737
377 WP3981 miRNA regulation of prostate cancer signaling pathways WP3981 -1.62 -3.53 0.856 0.741
378 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells WP4301 -1.34 -1.87 0.789 0.741
379 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy WP1559 -1.12 -1.9 0.796 0.743
380 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity WP299 -0.795 -0.903 0.675 0.743
381 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment WP4559 -0.63 -1.46 0.695 0.743
382 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation WP1425 -0.558 -0.703 0.673 0.748
383 WP4562 Canonical NF-KB pathway WP4562 -1.01 -2.06 0.748 0.749
384 WP2876 Pregnane X Receptor pathway WP2876 -0.632 -1.07 0.675 0.75
385 WP3965 Lipid Metabolism Pathway WP3965 -0.985 -1.44 0.727 0.75
386 WP4389 Bile Acids synthesis and enterohepatic circulation WP4389 -0.834 -1.22 0.712 0.75
387 WP399 Wnt Signaling Pathway and Pluripotency WP399 -0.763 -1.86 0.758 0.754
388 WP229 Irinotecan Pathway WP229 -0.407 -0.416 0.677 0.755
389 WP2333 Trans-sulfuration pathway WP2333 -0.6 -0.709 0.657 0.756
390 WP4742 Ketogenesis and Ketolysis WP4742 -0.602 -0.603 0.675 0.757
391 WP244 Alpha 6 Beta 4 signaling pathway WP244 -1.71 -2.98 0.869 0.758
392 WP288 NLR Proteins WP288 -1.4 -1.98 0.814 0.759
393 WP1424 Globo Sphingolipid Metabolism WP1424 -0.338 -0.223 0.658 0.761
394 WP501 GPCRs, Class C Metabotropic glutamate, pheromone WP501 -0.626 -0.568 0.692 0.764
395 WP61 Notch Signaling Pathway Netpath WP61 -0.953 -1.88 0.749 0.764
396 WP3926 ApoE and miR-146 in inflammation and atherosclerosis WP3926 -0.57 -1.15 0.667 0.765
397 WP4155 Endometrial cancer WP4155 -1.63 -3.89 0.93 0.765
398 WP2873 Aryl Hydrocarbon Receptor Pathway WP2873 -0.988 -1.62 0.789 0.771
399 WP3286 Copper homeostasis WP3286 -0.877 -1.57 0.777 0.771
400 WP4549 Fragile X Syndrome WP4549 -1.63 -2.41 0.864 0.771
401 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling WP3612 -0.586 -1.6 0.662 0.777
402 WP3300 Dual hijack model of Vif in HIV infection WP3300 -0.745 -0.704 0.683 0.778
403 WP4136 Fibrin Complement Receptor 3 Signaling Pathway WP4136 -1.22 -2.37 0.804 0.779
404 WP2324 AGE/RAGE pathway WP2324 -1.53 -3.55 0.891 0.781
405 WP4537 Hippo-Yap signaling pathway WP4537 -0.513 -0.578 0.684 0.781
406 WP2884 NRF2 pathway WP2884 -0.531 -0.814 0.72 0.783
407 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) WP4721 -0.592 -0.595 0.696 0.786
408 WP4478 LTF danger signal response pathway WP4478 -0.44 -1.63 0.663 0.788
409 WP4582 Cancer immunotherapy by CTLA4 blockade WP4582 -1.26 -2.05 0.837 0.789
410 WP75 Toll-like Receptor Signaling Pathway WP75 -1.67 -3.9 0.897 0.789
411 WP4018 Pathways in clear cell renal cell carcinoma WP4018 -1.19 -1.7 0.796 0.796
412 WP4726 Sphingolipid Metabolism (integrated pathway) WP4726 -0.528 -0.497 0.698 0.796
413 WP2533 Glycerophospholipid Biosynthetic Pathway WP2533 -0.899 -1.08 0.757 0.798
414 WP4519 Cerebral Organic Acidurias, including diseases WP4519 -0.617 -0.571 0.716 0.799
415 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits WP3678 -0.976 -1.2 0.803 0.8
416 WP2828 Bladder Cancer WP2828 -1.3 -2.7 0.919 0.804
417 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions WP4542 -0.709 -1.28 0.701 0.806
418 WP4565 Neural Crest Cell Migration in Cancer WP4565 -1.12 -2.44 0.827 0.806
419 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway WP2018 -1.76 -3.7 0.893 0.812
420 WP3933 Kennedy pathway from Sphingolipids WP3933 -0.72 -0.701 0.716 0.812
421 WP2854 Gene regulatory network modelling somitogenesis WP2854 -0.634 -0.728 0.729 0.816
422 WP3934 Leptin and adiponectin WP3934 -1.12 -1.19 0.744 0.817
423 WP4150 Wnt Signaling in Kidney Disease WP4150 -1.11 -1.66 0.82 0.824
424 WP3845 Canonical and Non-canonical Notch signaling WP3845 -1.1 -1.25 0.785 0.825
425 WP4479 Supression of HMGB1 mediated inflammation by THBD WP4479 -1.37 -2.33 0.795 0.827
426 WP2272 Pathogenic Escherichia coli infection WP2272 -1.14 -1.55 0.777 0.828
427 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway WP4206 -1.36 -1.58 0.816 0.829
428 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) WP2453 -1.36 -1.37 0.746 0.833
429 WP3945 TYROBP Causal Network WP3945 -1.84 -1.87 0.777 0.833
430 WP405 Eukaryotic Transcription Initiation WP405 -1.45 -1.35 0.744 0.833
431 WP2805 exRNA mechanism of action and biogenesis WP2805 -0.878 -0.846 0.738 0.834
432 WP357 Fatty Acid Biosynthesis WP357 -0.95 -1.05 0.746 0.837
433 WP3645 NAD+ biosynthetic pathways WP3645 -0.84 -0.859 0.749 0.846
434 WP47 Hedgehog Signaling Pathway Netpath WP47 -1.02 -0.992 0.76 0.846
435 WP696 Benzo(a)pyrene metabolism WP696 -1.35 -1.34 0.776 0.846
436 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression WP3879 -1.89 -2.73 0.876 0.847
437 WP4656 Joubert Syndrome WP4656 -1.59 -1.67 0.774 0.85
438 WP4205 MET in type 1 papillary renal cell carcinoma WP4205 -2.39 -4.04 0.97 0.854
439 WP716 Vitamin A and Carotenoid Metabolism WP716 -0.918 -0.994 0.805 0.854
440 WP4585 Cancer immunotherapy by PD-1 blockade WP4585 -1.82 -2.42 0.808 0.855
441 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus WP4142 -0.927 -0.896 0.789 0.856
442 WP100 Glutathione metabolism WP100 -1.31 -1.39 0.8 0.859
443 WP2526 PDGF Pathway WP2526 -1.99 -3.97 0.927 0.859
444 WP3858 Toll-like Receptor Signaling related to MyD88 WP3858 -1.39 -2.15 0.861 0.861
445 WP4655 Cytosolic DNA-sensing pathway WP4655 -1.59 -2.35 0.819 0.861
446 WP4522 Metabolic pathway of LDL, HDL and TG, including diseases WP4522 -0.842 -0.874 0.779 0.863
447 WP12 Osteoclast Signaling WP12 -1.19 -1.41 0.817 0.864
448 WP4197 The human immune response to tuberculosis WP4197 -1.4 -1.84 0.785 0.864
449 WP4241 Type 2 papillary renal cell carcinoma WP4241 -1.25 -1.6 0.837 0.869
450 WP4494 Selective expression of chemokine receptors during T-cell polarization WP4494 -1.58 -1.83 0.804 0.869
451 WP80 Nucleotide GPCRs WP80 -0.764 -0.737 0.781 0.871
452 WP4504 Cysteine and methionine catabolism WP4504 -1.06 -1.12 0.824 0.872
453 WP3982 miRNA regulation of p53 pathway in prostate cancer WP3982 -1.13 -1.89 0.832 0.873
454 WP3676 BDNF-TrkB Signaling WP3676 -1.81 -2.85 0.951 0.874
455 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS WP2572 -1.34 -1.85 0.865 0.876
456 WP2942 DDX1 as a regulatory component of the Drosha microprocessor WP2942 -1.18 -1.3 0.78 0.877
457 WP615 Senescence and Autophagy in Cancer WP615 -1.55 -2.97 0.862 0.879
458 WP3614 Photodynamic therapy-induced HIF-1 survival signaling WP3614 -1.12 -1.55 0.845 0.881
459 WP4153 Degradation pathway of sphingolipids, including diseases WP4153 -1.23 -1.17 0.813 0.881
460 WP4217 Ebola Virus Pathway on Host WP4217 -2.39 -3.15 0.899 0.881
461 WP581 EPO Receptor Signaling WP581 -2.1 -3.12 0.941 0.884
462 WP438 Non-homologous end joining WP438 -1.34 -1.33 0.799 0.888
463 WP4561 Cell migration and invasion through p75NTR WP4561 -1.32 -2.09 0.884 0.891
464 WP4722 Glycerolipids and Glycerophospholipids WP4722 -1.12 -1.09 0.817 0.893
465 WP106 Alanine and aspartate metabolism WP106 -1.07 -1.08 0.821 0.895
466 WP3413 NOTCH1 regulation of human endothelial cell calcification WP3413 -1.18 -1.25 0.855 0.898
467 WP2513 Nanoparticle triggered regulated necrosis WP2513 -1.49 -1.72 0.885 0.906
468 WP453 Inflammatory Response Pathway WP453 -1.94 -2.05 0.851 0.906
469 WP691 Tamoxifen metabolism WP691 -1.28 -1.3 0.849 0.906
470 WP4723 Omega-3/Omega-6 FA synthesis WP4723 -1.41 -1.44 0.847 0.907
471 WP111 Electron Transport Chain (OXPHOS system in mitochondria) WP111 -3.38 -3.27 0.864 0.909
472 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition WP3859 -1.69 -2.2 0.902 0.91
473 WP1449 Regulation of toll-like receptor signaling pathway WP1449 -2.09 -3.95 0.943 0.911
474 WP4159 GABA receptor Signaling WP4159 -1.34 -1.31 0.835 0.911
475 WP2877 Vitamin D Receptor Pathway WP2877 -1.05 -1.53 0.868 0.912
476 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation WP368 -1.56 -1.6 0.856 0.912
477 WP143 Fatty Acid Beta Oxidation WP143 -1.79 -1.81 0.884 0.919
478 WP4396 Nonalcoholic fatty liver disease WP4396 -2.89 -4.23 0.921 0.921
479 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway WP1433 -2.32 -2.82 0.916 0.923
480 WP3869 Cannabinoid receptor signaling WP3869 -1.61 -2.34 0.916 0.924
481 WP4146 Macrophage markers WP4146 -1.96 -1.96 0.864 0.925
482 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways WP3680 -2.27 -3.55 0.971 0.932
483 WP1471 Target Of Rapamycin (TOR) Signaling WP1471 -2.42 -3 0.932 0.936
484 WP534 Glycolysis and Gluconeogenesis WP534 -2.04 -2.12 0.888 0.939
485 WP692 Sulfation Biotransformation Reaction WP692 -1.77 -1.77 0.897 0.939
486 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling WP1982 -1.82 -2.14 0.912 0.943
487 WP4313 Ferroptosis WP4313 -1.81 -1.81 0.92 0.947
488 WP4329 miRNAs involvement in the immune response in sepsis WP4329 -1.84 -3.22 0.91 0.947
489 WP325 Triacylglyceride Synthesis WP325 -1.77 -1.75 0.9 0.949
490 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway WP3915 -2.67 -4.13 0.97 0.949
491 WP43 Oxidation by Cytochrome P450 WP43 -1.88 -1.83 0.924 0.952
492 WP4352 Ciliary landscape WP4352 -3.04 -2.98 0.927 0.952
493 WP4674 Head and Neck Squamous Cell Carcinoma WP4674 -2.59 -4.28 0.979 0.952
494 WP4758 Nephrotic syndrome WP4758 -2.14 -2.12 0.932 0.962
495 WP2509 Nanoparticle triggered autophagic cell death WP2509 -1.9 -2.29 0.917 0.964
496 WP710 DNA Damage Response (only ATM dependent) WP710 -2.87 -4.92 0.987 0.97
497 WP702 Metapathway biotransformation Phase I and II WP702 -2.54 -2.42 0.937 0.972
498 WP697 Estrogen metabolism WP697 -2.58 -2.61 0.96 0.977
499 WP4536 Genes related to primary cilium development (based on CRISPR) WP4536 -2.87 -2.68 0.937 0.98
500 WP4324 Mitochondrial complex I assembly model OXPHOS system WP4324 -3.86 -3.78 0.96 0.983
501 WP4532 Intraflagellar transport proteins binding to dynein WP4532 -2.93 -2.86 0.961 0.983
502 WP623 Oxidative phosphorylation WP623 -3.56 -3.52 0.953 0.984
503 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway WP4577 -3.37 -3.52 0.971 0.991

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"set_id","name","ID","Name","Size","Coverage","TDP.bound","TDP.estimate","SC.adjP","Comp.adjP"
"WP1600","Nicotine Metabolism",38,"WP1600",6,0.17,1,1,3.39506009152496e-24,3.39506009152496e-24
"WP2276","Glial Cell Differentiation",88,"WP2276",8,0.62,0.4,0.4,7.83386153710323e-26,5.70447887867626e-23
"WP4030","SCFA and skeletal muscle substrate metabolism",332,"WP4030",6,0.33,0.5,0.5,7.99040804992212e-20,7.99040804992212e-20
"WP334","GPCRs, Class B Secretin-like",210,"WP334",24,0.17,0.5,0.5,3.06579274689702e-21,1.60955895014834e-18
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation",60,"WP1991",13,0.69,0.888888888888889,1,5.37258163429194e-24,1.16900918682e-14
"WP206","Fatty Acid Omega Oxidation",76,"WP206",15,0.33,0.6,0.8,2.94021006969881e-38,1.31928124608757e-14
"WP3299","let-7 inhibition of ES cell reprogramming",205,"WP3299",15,0.33,0.6,0.6,1.69191698398203e-15,1.74501293167954e-14
"WP2023","Cell Differentiation - Index expanded",66,"WP2023",50,0.22,0.727272727272727,0.727272727272727,4.7856489956754e-16,2.33586928012365e-14
"WP2029","Cell Differentiation - Index",67,"WP2029",42,0.14,0.833333333333333,0.833333333333333,4.7856489956754e-16,2.33586928012365e-14
"WP2366","Butyrate-induced histone acetylation",105,"WP2366",2,1,0.5,0.5,1.10524321914212e-13,1.10524321914212e-13
"WP3297","EV release from cardiac cells and their functional effects",203,"WP3297",9,0.44,0.75,0.75,3.05550468161626e-32,3.37870774082303e-13
"WP554","ACE Inhibitor Pathway",530,"WP554",17,0.65,0.545454545454545,0.545454545454545,3.79036700534385e-25,5.54255202240522e-13
"WP4284","Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer",385,"WP4284",5,0.4,0.5,0.5,2.90591396510707e-11,2.90591396510707e-11
"WP2361","Gastric Cancer Network 1",103,"WP2361",29,0.76,0.727272727272727,0.727272727272727,3.61848623532521e-17,1.04514067941364e-10
"WP3944","Serotonin and anxiety-related events",309,"WP3944",13,0.46,0.666666666666667,0.666666666666667,1.45750470372243e-17,3.26510400891469e-09
"WP3947","Serotonin and anxiety",311,"WP3947",17,0.41,0.428571428571429,0.428571428571429,1.45750470372243e-17,3.26510400891469e-09
"WP1438","Influenza A virus infection",20,"WP1438",2,0.5,1,1,1.28737203377495e-08,1.28737203377495e-08
"WP383","Striated Muscle Contraction Pathway",265,"WP383",38,0.61,0.565217391304348,0.652173913043478,1.03667354058147e-21,1.30607861950122e-08
"WP2542","Sulindac Metabolic Pathway",133,"WP2542",5,0.8,0.5,0.75,4.35964063989166e-11,2.5564111779557e-08
"WP4222","Phosphodiesterases in neuronal function",366,"WP4222",55,0.56,0.419354838709677,0.483870967741935,1.11151548949677e-22,3.51064709129753e-08
"WP2943","Hypoxia-mediated EMT and Stemness",191,"WP2943",2,1,0.5,0.5,1.87433487284931e-07,1.87433487284931e-07
"WP2874","Liver X Receptor Pathway",175,"WP2874",10,0.5,0.4,0.4,9.83107916736652e-08,2.35055233649832e-07
"WP466","DNA Replication",480,"WP466",42,0.98,0.634146341463415,0.75609756097561,3.91911842678923e-14,4.20885218710584e-07
"WP545","Complement Activation",528,"WP545",22,0.68,0.466666666666667,0.466666666666667,3.75341311013175e-54,6.35126956702113e-07
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition",374,"WP4240",16,0.94,0.533333333333333,0.533333333333333,4.41152154021936e-12,6.65380602412947e-07
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells",395,"WP4300",28,0.61,0.411764705882353,0.588235294117647,1.55030261832076e-25,8.80494600850642e-07
"WP531","DNA Mismatch Repair",525,"WP531",22,0.95,0.523809523809524,0.571428571428571,3.57124737003596e-13,1.25145166671192e-06
"WP4589","Major receptors targeted by epinephrine and norepinephrine",471,"WP4589",15,0.73,0.636363636363636,0.636363636363636,1.11151548949677e-22,2.66815064645758e-06
"WP4760","PKC-gamma calcium signaling pathway in ataxia",508,"WP4760",22,0.55,0.416666666666667,0.583333333333333,6.52294438984146e-17,2.70719651941471e-06
"WP4191","Caloric restriction and aging",354,"WP4191",8,1,0.375,0.375,2.9447393377517e-11,3.80469322236512e-06
"WP2446","Retinoblastoma Gene in Cancer",117,"WP2446",88,0.98,0.546511627906977,0.593023255813954,1.96366351804733e-14,4.24785596200959e-06
"WP1992","Genes targeted by miRNAs in adipocytes",61,"WP1992",19,0.53,0.5,0.5,2.33586928012365e-14,8.49856030430427e-06
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma",406,"WP4337",17,0.76,0.538461538461538,0.615384615384615,1.55030261832076e-25,9.36831691097847e-06
"WP2645","Heroin metabolism",145,"WP2645",3,0.67,0.5,1,1.87627142351219e-05,1.87627142351219e-05
"WP2826","Cocaine metabolism",158,"WP2826",4,0.5,0.5,1,1.87627142351219e-05,1.87627142351219e-05
"WP1602","Nicotine Activity on Dopaminergic Neurons",40,"WP1602",22,0.5,0.636363636363636,0.818181818181818,2.50026382158374e-16,2.24952453555091e-05
"WP4545","Oxysterols derived from cholesterol",452,"WP4545",18,0.56,0.6,0.6,1.46780086933461e-09,2.36116814219851e-05
"WP45","G1 to S cell cycle control",430,"WP45",64,0.95,0.491803278688525,0.573770491803279,3.91911842678923e-14,2.89588011644963e-05
"WP1495","Glycine Metabolism",24,"WP1495",4,0.75,0.666666666666667,0.666666666666667,7.32732034249336e-10,2.91348117795513e-05
"WP2879","Farnesoid X Receptor Pathway",180,"WP2879",19,0.37,0.428571428571429,0.428571428571429,1.03671457774015e-11,0.000129931976156264
"WP34","Ovarian Infertility Genes",211,"WP34",32,0.53,0.411764705882353,0.411764705882353,8.1728342950092e-20,0.000152471085336278
"WP516","Hypertrophy Model",519,"WP516",20,0.75,0.466666666666667,0.533333333333333,1.73723649603814e-29,0.000166791537749366
"WP247","Small Ligand GPCRs",121,"WP247",19,0.53,0.6,0.8,3.77273931182897e-18,0.000182717661150266
"WP2363","Gastric Cancer Network 2",104,"WP2363",33,0.88,0.448275862068966,0.448275862068966,1.12863099668653e-15,0.000185246692246443
"WP170","Nuclear Receptors",44,"WP170",39,0.74,0.413793103448276,0.413793103448276,5.53853655041636e-45,0.000204208460415242
"WP3996","Ethanol effects on histone modifications",325,"WP3996",31,0.9,0.428571428571429,0.5,2.94021006969881e-38,0.000238758692258098
"WP4400","FABP4 in ovarian cancer",417,"WP4400",2,0.5,1,1,0.000245357066905715,0.000245357066905715
"WP58","Monoamine GPCRs",534,"WP58",33,0.15,0.6,0.6,2.66815064645758e-06,0.000266280491622695
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling",261,"WP3679",13,0.69,0.444444444444444,0.555555555555556,6.52294438984146e-17,0.000315427333264674
"WP2338","miRNA Biogenesis",99,"WP2338",8,0.75,0.5,0.5,5.52094234656009e-11,0.000633704399420972
"WP1455","Serotonin Transporter Activity",22,"WP1455",11,0.73,0.375,0.5,5.50097841431123e-07,0.000698192443745329
"WP4016","DNA IR-damage and cellular response via ATR",329,"WP4016",83,0.9,0.413333333333333,0.466666666666667,3.1984443894539e-16,0.000704575375419051
"WP179","Cell Cycle",48,"WP179",122,0.94,0.434782608695652,0.48695652173913,3.91911842678923e-14,0.000860192369254168
"WP2848","Differentiation Pathway",162,"WP2848",48,0.54,0.461538461538462,0.538461538461538,1.55030261832076e-25,0.000900218402911242
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)",155,"WP2815",10,1,0.5,0.7,3.47598200773578e-10,0.000979886474579196
"WP322","Osteoblast Signaling",199,"WP322",14,0.5,0.428571428571429,0.428571428571429,1.60955895014834e-18,0.00122105800992755
"WP4583","Biomarkers for urea cycle disorders",467,"WP4583",12,0.67,0.375,0.375,1.05891161032475e-42,0.00125836568297114
"WP3893","Development and heterogeneity of the ILC family",289,"WP3893",32,0.56,0.5,0.555555555555556,1.55030261832076e-25,0.00137922281926359
"WP2406","Cardiac Progenitor Differentiation",112,"WP2406",53,0.57,0.466666666666667,0.5,5.00019440781505e-25,0.0019450999028179
"WP558","Complement and Coagulation Cascades",531,"WP558",59,0.66,0.41025641025641,0.487179487179487,3.75341311013175e-54,0.00204133415581446
"WP2516","ATM Signaling Pathway",127,"WP2516",40,0.92,0.405405405405405,0.459459459459459,6.96540853859659e-18,0.00226170199642674
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation",282,"WP3876",13,0.85,0.454545454545455,0.454545454545455,1.1219536394885e-16,0.00287452439577986
"WP1545","miRNAs involved in DNA damage response",33,"WP1545",50,0.28,0.357142857142857,0.428571428571429,1.33825325438479e-13,0.00291300857028192
"WP3591","Sleep regulation",223,"WP3591",38,0.34,0.461538461538462,0.538461538461538,1.55030261832076e-25,0.00298637777295038
"WP2855","Dopaminergic Neurogenesis",166,"WP2855",30,0.33,0.4,0.6,8.1921343985721e-23,0.00300186445388684
"WP497","Urea cycle and metabolism of amino groups",515,"WP497",21,0.76,0.375,0.4375,1.21134935033961e-14,0.00350987947486594
"WP3407","FTO Obesity Variant Mechanism",212,"WP3407",8,0.88,0.428571428571429,0.428571428571429,2.9447393377517e-11,0.00376777148807062
"WP289","Myometrial Relaxation and Contraction Pathways",186,"WP289",158,0.76,0.391666666666667,0.466666666666667,4.72920713559152e-27,0.00465022180500277
"WP1530","miRNA Regulation of DNA Damage Response",27,"WP1530",93,0.69,0.375,0.453125,2.50026382158374e-16,0.00482551043459127
"WP4149","White fat cell differentiation",344,"WP4149",33,0.91,0.4,0.433333333333333,3.05550468161626e-32,0.00497520122591071
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)",154,"WP2814",13,0.92,0.5,0.5,8.1728342950092e-20,0.00569300599773054
"WP1603","Nicotine Activity on Chromaffin Cells",41,"WP1603",4,0.25,1,1,0.00581825930604642,0.00581825930604642
"WP4698","Vitamin D-sensitive calcium signaling in depression",486,"WP4698",41,0.54,0.363636363636364,0.5,6.52294438984146e-17,0.00581825930604642
"WP1971","Integrated Cancer Pathway",56,"WP1971",46,0.93,0.372093023255814,0.418604651162791,1.47590569356761e-12,0.00623426422936051
"WP4224","Purine metabolism and related disorders",368,"WP4224",22,0.86,0.368421052631579,0.421052631578947,3.39506009152496e-24,0.00660624701596271
"WP4259","Disorders of Folate Metabolism and Transport",379,"WP4259",13,0.85,0.454545454545455,0.454545454545455,7.32732034249336e-10,0.00660624701596271
"WP1601","Fluoropyrimidine Activity",39,"WP1601",34,0.82,0.392857142857143,0.5,7.38854762906026e-09,0.00668550277003425
"WP2806","Human Complement System",152,"WP2806",99,0.64,0.349206349206349,0.428571428571429,3.75341311013175e-54,0.00703640980157322
"WP707","DNA Damage Response",557,"WP707",69,0.9,0.370967741935484,0.451612903225806,2.50026382158374e-16,0.00934439177317729
"WP2895","Differentiation of white and brown adipocyte ",187,"WP2895",25,0.72,0.388888888888889,0.388888888888889,4.791051754563e-15,0.00971361957709086
"WP1995","Effects of Nitric Oxide",62,"WP1995",8,0.5,0.5,0.75,3.39506009152496e-24,0.0112147264561884
"WP136","Phase I biotransformations, non P450",10,"WP136",8,0.62,0.4,0.6,1.87627142351219e-05,0.0123569322150726
"WP536","Calcium Regulation in the Cardiac Cell",527,"WP536",152,0.7,0.355140186915888,0.429906542056075,7.92756655687513e-25,0.0169432049684982
"WP35","G Protein Signaling Pathways",216,"WP35",97,0.78,0.355263157894737,0.434210526315789,1.11151548949677e-22,0.0169866528793556
"WP241","One Carbon Metabolism",113,"WP241",31,0.81,0.4,0.48,7.32732034249336e-10,0.0170103318686093
"WP4571","Urea cycle and related diseases",464,"WP4571",9,0.67,0.5,0.5,6.0595781921859e-07,0.020635406510022
"WP4752","Base Excision Repair",503,"WP4752",31,0.97,0.4,0.466666666666667,3.57124737003596e-13,0.0220340720140378
"WP4720","Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway",491,"WP4720",9,0.44,0.5,0.5,4.43345799464762e-09,0.0230432320025256
"WP474","Endochondral Ossification",498,"WP474",65,0.83,0.351851851851852,0.462962962962963,4.81536487673321e-20,0.0246820506324245
"WP3875","ATR Signaling",281,"WP3875",9,0.89,0.375,0.375,4.60260415203756e-08,0.0248929712443472
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM",314,"WP3959",55,0.95,0.346153846153846,0.423076923076923,2.50026382158374e-16,0.0248929712443472
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement",458,"WP4560",18,0.94,0.411764705882353,0.470588235294118,6.52294438984146e-17,0.0254612754912739
"WP2525","Trans-sulfuration and one carbon metabolism",128,"WP2525",32,0.88,0.357142857142857,0.464285714285714,7.32732034249336e-10,0.0321645449138761
"WP98","Prostaglandin Synthesis and Regulation",568,"WP98",45,0.82,0.378378378378378,0.459459459459459,2.17394413943821e-22,0.0332806226599994
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS",397,"WP4304",31,0.52,0.375,0.375,7.83386153710323e-26,0.0344632354643189
"WP3599","Transcription factor regulation in adipogenesis",228,"WP3599",22,0.86,0.368421052631579,0.368421052631579,1.55030261832076e-25,0.0362388400314306
"WP1604","Codeine and Morphine Metabolism",42,"WP1604",15,0.27,0.5,0.5,6.49286728094462e-06,0.0372370714105519
"WP236","Adipogenesis",102,"WP236",131,0.79,0.346153846153846,0.413461538461538,3.75341311013175e-54,0.0373548404617312
"WP4661","Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension)",481,"WP4661",6,0.33,0.5,0.5,0.0431468886224066,0.0431468886224066
"WP3585","Cytosine methylation",222,"WP3585",9,0.89,0.375,0.5,7.49087453817701e-07,0.046146524101977
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein",279,"WP3872",22,0.91,0.35,0.45,1.28737203377495e-08,0.0485074090657223
"WP4399","MicroRNA network associated with chronic lymphocytic leukemia",416,"WP4399",7,0.57,0.5,0.5,1.28737203377495e-08,0.0485074090657223
"WP53","ID signaling pathway",523,"WP53",16,0.81,0.307692307692308,0.384615384615385,1.33825325438479e-13,0.0542788662751285
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling",564,"WP734",19,0.84,0.3125,0.375,1.69191698398203e-15,0.0542788662751285
"WP2881","Estrogen Receptor Pathway",182,"WP2881",13,0.77,0.3,0.4,2.58938282317479e-38,0.0594386193019534
"WP3963","Mevalonate pathway",315,"WP3963",7,1,0.285714285714286,0.428571428571429,0.00314781622146767,0.0618737980244723
"WP2197","Endothelin Pathways",81,"WP2197",34,0.68,0.304347826086957,0.391304347826087,4.72920713559152e-27,0.0668243064530906
"WP2355","Corticotropin-releasing hormone signaling pathway",100,"WP2355",93,0.78,0.328767123287671,0.410958904109589,5.53853655041636e-45,0.0668243064530906
"WP727","Monoamine Transport",561,"WP727",32,0.53,0.294117647058824,0.529411764705882,4.62070637396041e-12,0.0730490654877152
"WP167","Eicosanoid Synthesis",43,"WP167",27,0.67,0.333333333333333,0.388888888888889,2.17394413943821e-22,0.0735098081465718
"WP3624","Lung fibrosis",235,"WP3624",63,0.67,0.30952380952381,0.428571428571429,1.55030261832076e-25,0.080115977530217
"WP4584","Biomarkers for pyrimidine metabolism disorders",468,"WP4584",15,0.8,0.333333333333333,0.5,2.56816439701713e-12,0.0832724893457054
"WP4204","Tumor suppressor activity of SMARCB1",357,"WP4204",33,0.79,0.269230769230769,0.423076923076923,7.79200875278231e-09,0.0908144088489654
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)",490,"WP4719",30,0.7,0.333333333333333,0.380952380952381,2.17394413943821e-22,0.0918721376616465
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.",230,"WP3611",51,0.9,0.304347826086957,0.456521739130435,1.55030261832076e-25,0.093911573076689
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis",64,"WP2011",19,0.84,0.3125,0.4375,2.9447393377517e-11,0.103949453944605
"WP3892","Development of pulmonary dendritic cells and macrophage subsets",288,"WP3892",13,0.77,0.2,0.7,7.70437079680464e-06,0.111367348220358
"WP2431","Spinal Cord Injury",114,"WP2431",120,0.75,0.322222222222222,0.4,5.53853655041636e-45,0.114048118916392
"WP272","Blood Clotting Cascade",148,"WP272",23,0.52,0.333333333333333,0.5,1.05891161032475e-42,0.114803285411883
"WP117","GPCRs, Other",5,"WP117",94,0.23,0.318181818181818,0.363636363636364,3.77273931182897e-18,0.120172770046016
"WP3596","miR-517 relationship with ARCN1 and USP1",227,"WP3596",5,1,0.2,0.4,7.70437079680464e-06,0.123137649892892
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance",257,"WP3672",12,0.58,0.285714285714286,0.428571428571429,1.61117377276123e-06,0.123137649892892
"WP3995","Prion disease pathway",324,"WP3995",37,0.84,0.258064516129032,0.419354838709677,1.42295577093001e-17,0.148008766451471
"WP4147","PTF1A related regulatory pathway",342,"WP4147",11,0.45,0.2,0.4,0.000808563677475246,0.156029921726251
"WP2849","Hematopoietic Stem Cell Differentiation",163,"WP2849",63,0.68,0.325581395348837,0.395348837209302,1.4645909158934e-29,0.156167098725433
"WP3958","GPR40 Pathway",313,"WP3958",16,0.81,0.307692307692308,0.538461538461538,1.06179313771239e-06,0.156624702837221
"WP4249","Hedgehog Signaling Pathway",376,"WP4249",44,0.77,0.264705882352941,0.411764705882353,6.45939424963396e-09,0.171056939850016
"WP2846","Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation",161,"WP2846",3,0.33,0,1,0.191601747736878,0.191601747736878
"WP3408","Evolocumab Mechanism",213,"WP3408",3,0.33,0,1,0.191601747736878,0.191601747736878
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy",80,"WP2118",76,0.74,0.303571428571429,0.410714285714286,6.58880500842654e-23,0.19520059624092
"WP3640","Imatinib and Chronic Myeloid Leukemia",243,"WP3640",21,0.95,0.3,0.4,3.36912948711107e-08,0.202640916207215
"WP2007","Iron metabolism in placenta",63,"WP2007",12,0.67,0.25,0.375,0.000425327317103322,0.20667484530917
"WP129","Matrix Metalloproteinases",8,"WP129",30,0.73,0.272727272727273,0.409090909090909,1.66846236358396e-28,0.217106999492912
"WP4754","IL-18 signaling pathway",505,"WP4754",279,0.8,0.265765765765766,0.373873873873874,5.53853655041636e-45,0.224063872360977
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness",207,"WP3301",13,1,0.230769230769231,0.384615384615385,7.1834548445351e-10,0.236415904297976
"WP704","Methylation Pathways",555,"WP704",10,0.7,0.142857142857143,0.428571428571429,1.10795143781028e-12,0.241165469354808
"WP3930","EDA Signalling in Hair Follicle Development",297,"WP3930",14,0.64,0.222222222222222,0.555555555555556,6.78928901696758e-07,0.24293224118149
"WP3967","miR-509-3p alteration of YAP1/ECM axis",317,"WP3967",19,0.89,0.235294117647059,0.352941176470588,3.92971708713555e-06,0.246081089028509
"WP2858","Ectoderm Differentiation",168,"WP2858",144,0.78,0.285714285714286,0.366071428571429,6.10911950894992e-26,0.251410075884791
"WP428","Wnt Signaling",384,"WP428",118,0.79,0.301075268817204,0.365591397849462,5.00019440781505e-25,0.251410075884791
"WP1434","Osteopontin Signaling",19,"WP1434",13,1,0.230769230769231,0.461538461538462,1.51229007711679e-12,0.257536764433672
"WP176","Folate Metabolism",46,"WP176",73,0.6,0.295454545454545,0.409090909090909,1.55030261832076e-25,0.257536764433672
"WP28","Selenium Metabolism and Selenoproteins",150,"WP28",46,0.61,0.25,0.392857142857143,2.4987918295779e-23,0.257536764433672
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)",160,"WP2840",88,0.64,0.267857142857143,0.375,1.4645909158934e-29,0.257536764433672
"WP3617","Photodynamic therapy-induced NF-kB survival signaling",234,"WP3617",35,0.86,0.233333333333333,0.4,1.55030261832076e-25,0.257536764433672
"WP2059","Alzheimers Disease",75,"WP2059",150,0.46,0.260869565217391,0.36231884057971,6.52294438984146e-17,0.264407820025205
"WP4658","Small cell lung cancer",478,"WP4658",98,0.91,0.269662921348315,0.359550561797753,1.33825325438479e-13,0.266714097046007
"WP237","Glucocorticoid and Mineralcorticoid Metabolism",107,"WP237",8,0.25,0,0.5,0.273007477872406,0.273007477872406
"WP3287","Overview of nanoparticle effects",202,"WP3287",19,0.79,0.266666666666667,0.4,1.55030261832076e-25,0.292450502904674
"WP4586","Metabolism of alpha-linolenic acid",470,"WP4586",7,0.86,0.166666666666667,0.5,0.0386740237126384,0.296626199889639
"WP3580","Methionine De Novo and Salvage Pathway",220,"WP3580",22,0.86,0.210526315789474,0.368421052631579,4.35964063989166e-11,0.301026666733762
"WP4481","Resistin as a regulator of inflammation",422,"WP4481",33,0.85,0.25,0.357142857142857,1.55030261832076e-25,0.310639518319511
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ",226,"WP3595",7,0.86,0.333333333333333,0.5,1.28871879017951e-06,0.311537001183337
"WP4225","Pyrimidine metabolism and related diseases",369,"WP4225",17,0.71,0.25,0.416666666666667,1.65319775729734e-07,0.312696646387934
"WP24","Peptide GPCRs",111,"WP24",75,0.28,0.285714285714286,0.428571428571429,1.91116166189054e-21,0.317365436064072
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma",405,"WP4336",91,0.76,0.289855072463768,0.36231884057971,5.00019440781505e-25,0.320170838547363
"WP4462","Platelet-mediated interactions with vascular and circulating cells",418,"WP4462",17,0.88,0.266666666666667,0.4,1.28837373141904e-08,0.341095356415239
"WP4493","Cells and Molecules involved in local acute inflammatory response ",426,"WP4493",17,0.76,0.307692307692308,0.384615384615385,1.55030261832076e-25,0.341095356415239
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway",256,"WP3670",21,0.81,0.176470588235294,0.352941176470588,2.45932835171728e-12,0.357129134137342
"WP4538","Regulatory circuits of the STAT3 signaling pathway",447,"WP4538",79,0.85,0.26865671641791,0.343283582089552,1.91116166189054e-21,0.363878327573958
"WP229","Irinotecan Pathway",90,"WP229",13,0.54,0.285714285714286,0.428571428571429,1.87627142351219e-05,0.372595026103777
"WP4172","PI3K-Akt Signaling Pathway",350,"WP4172",345,0.73,0.281746031746032,0.361111111111111,1.96319556679318e-26,0.389653492019368
"WP3584","MECP2 and Associated Rett Syndrome",221,"WP3584",71,0.72,0.274509803921569,0.352941176470588,2.08918249834541e-15,0.389709140526829
"WP530","Cytokines and Inflammatory Response",524,"WP530",27,0.52,0.214285714285714,0.357142857142857,1.55030261832076e-25,0.394616722859002
"WP3888","VEGFA-VEGFR2 Signaling Pathway",286,"WP3888",438,0.92,0.255583126550869,0.359801488833747,5.53853655041636e-45,0.415827475604265
"WP4537","Hippo-Yap signaling pathway",446,"WP4537",23,1,0.130434782608696,0.347826086956522,1.54778757247964e-06,0.425582638865984
"WP4673","Genes involved in male infertility",483,"WP4673",155,0.55,0.223529411764706,0.352941176470588,8.15687289296435e-21,0.434708802034794
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer",378,"WP4258",104,0.73,0.276315789473684,0.342105263157895,5.00019440781505e-25,0.442641490692933
"WP1528","Physiological and Pathological Hypertrophy of the Heart",26,"WP1528",25,0.96,0.291666666666667,0.375,1.45750470372243e-17,0.443468145964458
"WP1539","Angiogenesis",30,"WP1539",24,1,0.25,0.375,2.08918249834541e-15,0.443468145964458
"WP2586","Aryl Hydrocarbon Receptor Netpath",136,"WP2586",48,0.83,0.225,0.35,1.44400359316927e-08,0.452666162731714
"WP2865","IL1 and megakaryocytes in obesity",171,"WP2865",25,0.84,0.238095238095238,0.380952380952381,5.19525794232389e-10,0.452666162731714
"WP384","Apoptosis Modulation by HSP70",266,"WP384",19,0.95,0.166666666666667,0.388888888888889,6.96540853859659e-18,0.452666162731714
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",556,"WP706",164,0.61,0.31,0.35,7.75341732836066e-26,0.452666162731714
"WP1742","TP53 Network",45,"WP1742",20,0.9,0.222222222222222,0.388888888888889,1.28737203377495e-08,0.467750156194828
"WP2507","Nanomaterial induced apoptosis",124,"WP2507",20,0.95,0.105263157894737,0.368421052631579,1.28737203377495e-08,0.467750156194828
"WP2267","Synaptic Vesicle Pathway",86,"WP2267",52,0.6,0.258064516129032,0.354838709677419,6.97840140254166e-30,0.492132771972666
"WP2038","Regulation of Microtubule Cytoskeleton",73,"WP2038",49,0.86,0.285714285714286,0.357142857142857,5.70447887867626e-23,0.498108980109511
"WP3594","Circadian rhythm related genes",225,"WP3594",207,0.67,0.289855072463768,0.340579710144928,1.86144948015588e-42,0.502912219194388
"WP186","Homologous recombination",51,"WP186",13,0.92,0.333333333333333,0.333333333333333,3.57124737003596e-13,0.503680038828547
"WP4299","Lamin A-processing pathway",392,"WP4299",3,1,0.333333333333333,0.333333333333333,0.0375633720082355,0.525565992204199
"WP26","Signal Transduction of S1P Receptor",139,"WP26",26,0.92,0.208333333333333,0.333333333333333,1.36035451223937e-09,0.537154575485495
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",299,"WP3932",309,0.79,0.246913580246914,0.337448559670782,1.96319556679318e-26,0.55485006897197
"WP3529","Zinc homeostasis",218,"WP3529",37,0.65,0.208333333333333,0.333333333333333,1.09751947262418e-13,0.559735276252208
"WP3613","Photodynamic therapy-induced unfolded protein response",232,"WP3613",29,0.83,0.25,0.333333333333333,1.63572753987345e-09,0.592395677119481
"WP455","GPCRs, Class A Rhodopsin-like",454,"WP455",258,0.22,0.241379310344828,0.327586206896552,1.91116166189054e-21,0.594474156958518
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation",198,"WP314",44,0.91,0.175,0.325,1.28737203377495e-08,0.596740036001061
"WP4321","Thermogenesis",401,"WP4321",108,0.83,0.266666666666667,0.333333333333333,2.44977316588364e-24,0.602303776230422
"WP1533","Vitamin B12 Metabolism",29,"WP1533",53,0.57,0.2,0.333333333333333,1.55030261832076e-25,0.625924461178548
"WP254","Apoptosis",132,"WP254",86,0.93,0.225,0.3375,6.96540853859659e-18,0.630454225897172
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)",157,"WP2817",33,0.76,0.32,0.32,8.1728342950092e-20,0.631033926043019
"WP4286","Genotoxicity pathway",386,"WP4286",63,0.78,0.244897959183673,0.326530612244898,6.52294438984146e-17,0.633739231633592
"WP4228","Vitamin B6-dependent and responsive disorders",370,"WP4228",5,0.8,0.25,0.25,0.00334024416831868,0.635216999029685
"WP306","Focal Adhesion",195,"WP306",202,0.86,0.248554913294798,0.323699421965318,1.96319556679318e-26,0.661870634611933
"WP3941","Oxidative Damage",306,"WP3941",41,0.9,0.243243243243243,0.324324324324324,1.28737203377495e-08,0.699923750757195
"WP561","Heme Biosynthesis",533,"WP561",9,0.89,0.25,0.25,6.5794345319789e-05,0.701076830955824
"WP4541","Hippo-Merlin Signaling Dysregulation",450,"WP4541",123,0.77,0.221052631578947,0.315789473684211,5.28168194977512e-22,0.723397294815617
"WP2064","Neural Crest Differentiation",77,"WP2064",102,0.63,0.25,0.328125,1.94200095136959e-19,0.727478052387628
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits",260,"WP3678",17,1,0.117647058823529,0.294117647058824,6.04285700943382e-06,0.727478052387628
"WP3935","Leptin Insulin Overlap",302,"WP3935",17,0.82,0.285714285714286,0.285714285714286,9.45573250233619e-09,0.741018446305419
"WP1772","Apoptosis Modulation and Signaling",47,"WP1772",93,0.85,0.189873417721519,0.316455696202532,6.96540853859659e-18,0.744856843612274
"WP2877","Vitamin D Receptor Pathway",178,"WP2877",186,0.63,0.271186440677966,0.322033898305085,7.99040804992212e-20,0.818823949216948
"WP1591","Heart Development",37,"WP1591",46,0.65,0.266666666666667,0.3,1.16900918682e-14,0.842767793418932
"WP4357","NRF2-ARE regulation",410,"WP4357",23,0.96,0.227272727272727,0.318181818181818,6.33815645362995e-08,0.87065004588454
"WP2882","Nuclear Receptors Meta-Pathway",183,"WP2882",322,0.69,0.238738738738739,0.315315315315315,2.58938282317479e-38,0.88225486075262
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway",68,"WP2032",68,0.91,0.274193548387097,0.32258064516129,8.47368187861688e-16,0.884931793800649
"WP3998","Prader-Willi and Angelman Syndrome",326,"WP3998",66,0.45,0.333333333333333,0.333333333333333,2.9765880724211e-12,0.892842095899067
"WP2369","Histone Modifications",106,"WP2369",70,0.43,0.166666666666667,0.3,4.29629046913145e-07,0.898693967045816
"WP4540","Pathways Regulating Hippo Signaling",449,"WP4540",99,0.81,0.225,0.325,1.45750470372243e-17,0.900720485325998
"WP4022","Pyrimidine metabolism",331,"WP4022",87,0.91,0.253164556962025,0.329113924050633,3.57124737003596e-13,0.90295173404126
"WP4484","Control of immune tolerance by vasoactive intestinal peptide",425,"WP4484",13,0.31,0,0.25,0.189083662421517,0.90837549057179
"WP3527","Preimplantation Embryo",217,"WP3527",60,0.52,0.193548387096774,0.290322580645161,1.4645909158934e-29,0.920619031124591
"WP408","Oxidative Stress",335,"WP408",34,0.85,0.206896551724138,0.310344827586207,2.4987918295779e-23,0.926181011736354
"WP4297","Thiamine metabolic pathways",390,"WP4297",9,0.89,0,0.25,0.171095325811961,0.927438681383965
"WP1984","Integrated Breast Cancer Pathway",59,"WP1984",155,0.92,0.27972027972028,0.314685314685315,3.61848623532521e-17,0.929014479457768
"WP3972","PDGFR-beta pathway",320,"WP3972",29,1,0.241379310344828,0.275862068965517,1.45750470372243e-17,0.936983896443534
"WP15","Selenium Micronutrient Network",25,"WP15",92,0.54,0.2,0.32,1.55030261832076e-25,0.94158668008034
"WP1423","Ganglio Sphingolipid Metabolism",14,"WP1423",13,0.62,0.25,0.25,4.87851969602103e-17,0.954898577153562
"WP4298","Viral Acute Myocarditis",391,"WP4298",85,0.82,0.228571428571429,0.314285714285714,1.55030261832076e-25,0.960973679911299
"WP2374","Oncostatin M Signaling Pathway",109,"WP2374",66,0.97,0.25,0.3125,1.45750470372243e-17,0.962619223865447
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling",270,"WP3850",31,0.94,0.241379310344828,0.310344827586207,2.9447393377517e-11,0.979681670178472
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex",250,"WP3657",22,0.86,0.315789473684211,0.315789473684211,1.28737203377495e-08,0.990973876560315
"WP465","Tryptophan metabolism",474,"WP465",42,0.64,0.259259259259259,0.333333333333333,1.2733947666864e-33,0.991085216247916
"WP1541","Energy Metabolism",31,"WP1541",48,0.88,0.30952380952381,0.333333333333333,4.7856489956754e-16,0.991457884585696
"WP4148","Splicing factor NOVA regulated synaptic proteins",343,"WP4148",42,0.74,0.258064516129032,0.32258064516129,8.59680057967434e-17,0.99308777325874
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway",110,"WP2380",144,0.85,0.227642276422764,0.284552845528455,2.46076597989882e-17,0.993357395961217
"WP183","Proteasome Degradation",49,"WP183",64,0.91,0.189655172413793,0.258620689655172,0.000102727400071607,0.993739319892961
"WP3942","PPAR signaling pathway",307,"WP3942",67,0.67,0.244444444444444,0.266666666666667,4.45382103461115e-22,0.993946338790036
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3",407,"WP4341",71,0.82,0.224137931034483,0.310344827586207,1.55030261832076e-25,0.997223465039722
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway",71,"WP2036",42,0.95,0.2,0.3,1.55030261832076e-25,0.998306181536745
"WP262","EBV LMP1 signaling",140,"WP262",24,0.83,0.2,0.3,1.31802719833037e-09,0.998306181536745
"WP4008","NO/cGMP/PKG mediated Neuroprotection",328,"WP4008",48,0.52,0.24,0.32,3.3920313877351e-19,0.998306181536745
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment",421,"WP4480",9,0.89,0.125,0.25,1.55030261832076e-25,0.998306181536745
"WP411","mRNA Processing",337,"WP411",133,0.92,0.204918032786885,0.286885245901639,7.40715848733595e-20,0.999556795185293
"WP4290","Metabolic reprogramming in colon cancer",388,"WP4290",44,0.89,0.230769230769231,0.282051282051282,1.21134935033961e-14,0.999559974562214
"WP2583","T-Cell Receptor and Co-stimulatory Signaling",135,"WP2583",29,0.93,0.0740740740740741,0.185185185185185,0.0020390189701393,0.999564052655054
"WP2113","Type III interferon signaling",79,"WP2113",10,0.6,0.333333333333333,0.333333333333333,0.000341914298724229,0.999577405939352
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway",83,"WP2203",47,0.96,0.2,0.266666666666667,1.55030261832076e-25,0.999581638329153
"WP3929","Chemokine signaling pathway",296,"WP3929",165,0.75,0.233870967741935,0.306451612903226,1.11151548949677e-22,0.999581638329153
"WP2878","PPAR Alpha Pathway",179,"WP2878",26,0.62,0.3125,0.3125,2.35000378034819e-10,0.999593630002801
"WP4211","Transcriptional cascade regulating adipogenesis",361,"WP4211",13,1,0.307692307692308,0.307692307692308,3.05550468161626e-32,0.999597380647255
"WP395","IL-4 Signaling Pathway",312,"WP395",55,0.96,0.169811320754717,0.264150943396226,1.21006371795151e-15,0.999598637344068
"WP4756","Renin Angiotensin Aldosterone System (RAAS)",506,"WP4756",44,0.64,0.214285714285714,0.285714285714286,3.79036700534385e-25,0.999600844420397
"WP2037","Prolactin Signaling Pathway",72,"WP2037",76,0.96,0.164383561643836,0.246575342465753,1.21006371795151e-15,0.999622158178795
"WP3646","Hepatitis C and Hepatocellular Carcinoma",246,"WP3646",50,0.88,0.25,0.340909090909091,1.55030261832076e-25,0.999661972130556
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR",215,"WP3414",37,0.73,0.259259259259259,0.296296296296296,1.30274002920557e-12,0.999679395222021
"WP1422","Sphingolipid pathway",13,"WP1422",30,0.8,0.166666666666667,0.25,3.69949076638916e-07,0.999680873684117
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus",340,"WP4142",20,0.75,0.2,0.2,1.78651764239784e-05,0.999680873684117
"WP4725","Sphingolipid Metabolism (general overview)",496,"WP4725",24,0.83,0.2,0.25,1.3073328528498e-06,0.999680873684117
"WP2359","Parkin-Ubiquitin Proteasomal System pathway",101,"WP2359",70,0.84,0.152542372881356,0.23728813559322,1.33825325438479e-13,0.999692096078023
"WP2911","miRNA targets in ECM and membrane receptors",188,"WP2911",43,0.51,0.227272727272727,0.272727272727273,1.96319556679318e-26,0.999694369321929
"WP4262","Breast cancer pathway",380,"WP4262",157,0.77,0.214876033057851,0.28099173553719,8.1728342950092e-20,0.999736194038243
"WP2636","Common Pathways Underlying Drug Addiction",141,"WP2636",42,0.57,0.166666666666667,0.25,8.80436312071741e-23,0.999745706039956
"WP2828","Bladder Cancer",159,"WP2828",41,0.93,0.184210526315789,0.289473684210526,2.88662493064661e-07,0.999745706039956
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling",231,"WP3612",24,0.88,0.0952380952380952,0.238095238095238,1.21006371795151e-15,0.999752419955776
"WP4312","Rett syndrome causing genes",398,"WP4312",49,0.76,0.216216216216216,0.297297297297297,1.22943627951508e-14,0.999766525303437
"WP2533","Glycerophospholipid Biosynthetic Pathway",130,"WP2533",30,0.83,0.08,0.16,3.98592395806362e-10,0.999787685558907
"WP3940","One carbon metabolism and related pathways",305,"WP3940",54,0.72,0.230769230769231,0.256410256410256,2.86780567028817e-25,0.999787685558907
"WP4657","22q11.2 Deletion Syndrome",477,"WP4657",92,0.63,0.258620689655172,0.310344827586207,5.10653311534479e-29,0.999801314777508
"WP382","MAPK Signaling Pathway",264,"WP382",249,0.78,0.261538461538462,0.302564102564103,5.53853655041636e-45,0.999829075430104
"WP4666","Hepatitis B infection",482,"WP4666",154,0.84,0.2,0.276923076923077,1.55030261832076e-25,0.999846173141814
"WP107","Translation Factors",3,"WP107",54,0.87,0.234042553191489,0.276595744680851,8.52450711689985e-13,0.999852323093054
"WP1424","Globo Sphingolipid Metabolism",15,"WP1424",21,0.95,0.2,0.2,4.87851969602103e-17,0.999852323093054
"WP1584","Type II diabetes mellitus",35,"WP1584",22,0.64,0.142857142857143,0.142857142857143,7.99040804992212e-20,0.999852323093054
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway",65,"WP2018",55,0.95,0.0961538461538462,0.192307692307692,1.21006371795151e-15,0.999852323093054
"WP231","TNF alpha Signaling Pathway",94,"WP231",94,0.94,0.204545454545455,0.284090909090909,1.55030261832076e-25,0.999852323093054
"WP2371","Parkinsons Disease Pathway",108,"WP2371",84,0.37,0.193548387096774,0.290322580645161,6.96540853859659e-18,0.999852323093054
"WP244","Alpha 6 Beta 4 signaling pathway",116,"WP244",35,0.94,0.121212121212121,0.181818181818182,2.61142544133486e-11,0.999852323093054
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)",119,"WP2453",16,0.94,0.0666666666666667,0.0666666666666667,1.10524321914212e-13,0.999852323093054
"WP2456","HIF1A and PPARG regulation of glycolysis",120,"WP2456",8,0.75,0.166666666666667,0.166666666666667,0.00320215171958638,0.999852323093054
"WP2854","Gene regulatory network modelling somitogenesis ",165,"WP2854",11,0.55,0.166666666666667,0.166666666666667,0.0396104615656672,0.999852323093054
"WP2870","Extracellular vesicle-mediated signaling in recipient cells",173,"WP2870",30,0.9,0.185185185185185,0.222222222222222,1.47923810515956e-16,0.999852323093054
"WP3","Phytochemical activity on NRF2 transcriptional activation",193,"WP3",15,0.93,0.0714285714285714,0.214285714285714,0.00237947159212301,0.999852323093054
"WP3286","Copper homeostasis",201,"WP3286",54,0.87,0.234042553191489,0.297872340425532,3.71596808468601e-16,0.999852323093054
"WP3298","Melatonin metabolism and effects",204,"WP3298",42,0.62,0.269230769230769,0.307692307692308,1.86144948015588e-42,0.999852323093054
"WP3413","NOTCH1 regulation of human endothelial cell calcification",214,"WP3413",18,0.89,0.125,0.125,2.23804617426945e-12,0.999852323093054
"WP3601","Composition of Lipid Particles",229,"WP3601",10,0.4,0,0.25,0.191601747736878,0.999852323093054
"WP3633","Caffeine and Theobromine metabolism",239,"WP3633",4,0.25,0,0,0.999852323093054,0.999852323093054
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds",253,"WP3664",18,0.89,0.1875,0.3125,8.33920870140507e-09,0.999852323093054
"WP3845","Canonical and Non-canonical Notch signaling",268,"WP3845",27,0.81,0.0909090909090909,0.181818181818182,0.000608063456248664,0.999852323093054
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition",274,"WP3859",18,0.94,0.0588235294117647,0.0588235294117647,2.97846854097459e-06,0.999852323093054
"WP3931","ESC Pluripotency Pathways",298,"WP3931",119,0.7,0.265060240963855,0.289156626506024,1.04633266994318e-15,0.999852323093054
"WP3945","TYROBP Causal Network",310,"WP3945",63,0.9,0.12280701754386,0.175438596491228,1.51229007711679e-12,0.999852323093054
"WP3965","Lipid Metabolism Pathway",316,"WP3965",29,0.9,0.269230769230769,0.269230769230769,1.10524321914212e-13,0.999852323093054
"WP3982","miRNA regulation of p53 pathway in prostate cancer",322,"WP3982",34,0.68,0.0869565217391304,0.217391304347826,4.32292432502445e-07,0.999852323093054
"WP4153","Degradation pathway of sphingolipids, including diseases",346,"WP4153",10,0.8,0,0,0.999852323093054,0.999852323093054
"WP4156","Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases",348,"WP4156",2,1,0,0,0.999852323093054,0.999852323093054
"WP4159","GABA receptor Signaling",349,"WP4159",33,0.39,0.0769230769230769,0.0769230769230769,0.0013300266749614,0.999852323093054
"WP4220","Neurotransmitter Disorders",365,"WP4220",4,0.25,0,0,0.999852323093054,0.999852323093054
"WP43","Oxidation by Cytochrome P450",393,"WP43",63,0.48,0.133333333333333,0.166666666666667,7.53565262981462e-07,0.999852323093054
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome",400,"WP4320",39,0.56,0.227272727272727,0.227272727272727,5.61788394294512e-16,0.999852323093054
"WP4342","Vitamins A and D - action mechanisms",408,"WP4342",3,1,0.333333333333333,0.333333333333333,1.20099662033474e-06,0.999852323093054
"WP437","EGF/EGFR Signaling Pathway",411,"WP437",164,0.95,0.206451612903226,0.232258064516129,1.4645909158934e-29,0.999852323093054
"WP4482","Vitamin D in inflammatory diseases",423,"WP4482",22,0.95,0.19047619047619,0.285714285714286,1.16949610776226e-27,0.999852323093054
"WP4483","Relationship between inflammation, COX-2 and EGFR",424,"WP4483",25,0.88,0.272727272727273,0.318181818181818,6.500496706318e-05,0.999852323093054
"WP4519","Cerebral Organic Acidurias, including diseases",435,"WP4519",7,1,0.285714285714286,0.285714285714286,1.97077141104003e-05,0.999852323093054
"WP4522","Metabolic pathway of LDL, HDL and TG, including diseases",437,"WP4522",17,0.53,0,0.222222222222222,0.0725218231021907,0.999852323093054
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology",444,"WP4535",46,0.89,0.24390243902439,0.268292682926829,1.11151548949677e-22,0.999852323093054
"WP4549","Fragile X Syndrome ",453,"WP4549",123,0.76,0.172043010752688,0.21505376344086,6.52294438984146e-17,0.999852323093054
"WP4562","Canonical NF-KB pathway",460,"WP4562",8,1,0,0.125,0.452666162731714,0.999852323093054
"WP4585","Cancer immunotherapy by PD-1 blockade",469,"WP4585",24,0.88,0.0952380952380952,0.19047619047619,2.79548473355309e-05,0.999852323093054
"WP4724","Omega-9 FA synthesis",495,"WP4724",16,0.75,0.166666666666667,0.25,9.83107916736652e-08,0.999852323093054
"WP4758","Nephrotic syndrome",507,"WP4758",45,0.73,0.151515151515152,0.181818181818182,7.19331431961561e-10,0.999852323093054
"WP550","Biogenic Amine Synthesis",529,"WP550",16,0.19,0.333333333333333,0.333333333333333,0.0013300266749614,0.999852323093054
"WP100","Glutathione metabolism",1,"WP100",23,0.7,0.0625,0.0625,2.4987918295779e-23,0.999852323093054
"WP106","Alanine and aspartate metabolism",2,"WP106",12,0.58,0.142857142857143,0.142857142857143,0.0013300266749614,0.999852323093054
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)",4,"WP111",106,0.66,0.0714285714285714,0.128571428571429,1.43014316833318e-19,0.999852323093054
"WP12","Osteoclast Signaling",6,"WP12",16,0.75,0.166666666666667,0.25,1.51229007711679e-12,0.999852323093054
"WP134","Pentose Phosphate Metabolism",9,"WP134",7,1,0,0.142857142857143,0.154107526146787,0.999852323093054
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling",12,"WP1403",69,0.81,0.178571428571429,0.25,7.99040804992212e-20,0.999852323093054
"WP143","Fatty Acid Beta Oxidation",17,"WP143",34,0.79,0.111111111111111,0.111111111111111,6.0888051023505e-05,0.999852323093054
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway",18,"WP1433",41,0.78,0.0625,0.125,4.08325260581342e-05,0.999852323093054
"WP1449","Regulation of toll-like receptor signaling pathway",21,"WP1449",145,0.77,0.117117117117117,0.198198198198198,1.55030261832076e-25,0.999852323093054
"WP1471","Target Of Rapamycin (TOR) Signaling",23,"WP1471",37,0.92,0.0882352941176471,0.117647058823529,8.28904921253337e-06,0.999852323093054
"WP1531","Vitamin D Metabolism",28,"WP1531",10,0.7,0.285714285714286,0.285714285714286,2.36116814219851e-05,0.999852323093054
"WP1544","MicroRNAs in cardiomyocyte hypertrophy",32,"WP1544",101,0.75,0.223684210526316,0.263157894736842,1.45750470372243e-17,0.999852323093054
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses",36,"WP1589",9,0.89,0.125,0.25,2.91348117795513e-05,0.999852323093054
"WP185","Integrin-mediated Cell Adhesion",50,"WP185",104,0.84,0.195402298850575,0.218390804597701,5.28168194977512e-22,0.999852323093054
"WP1941","Peroxisomal beta-oxidation of tetracosanoyl-CoA",52,"WP1941",4,1,0,0,0.999852323093054,0.999852323093054
"WP195","IL-1 signaling pathway",54,"WP195",57,0.96,0.127272727272727,0.181818181818182,1.5288509675647e-18,0.999852323093054
"WP197","Cholesterol Biosynthesis Pathway",55,"WP197",15,0.93,0.214285714285714,0.285714285714286,2.36116814219851e-05,0.999852323093054
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling",58,"WP1982",73,0.88,0.140625,0.171875,1.10524321914212e-13,0.999852323093054
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway",70,"WP2035",27,0.81,0.181818181818182,0.272727272727273,1.84528135455106e-08,0.999852323093054
"WP205","IL-7 Signaling Pathway",74,"WP205",25,1,0.16,0.2,0.000601597866207179,0.999852323093054
"WP2112","IL17 signaling pathway",78,"WP2112",32,0.84,0.148148148148148,0.222222222222222,1.31802719833037e-09,0.999852323093054
"WP22","IL-9 Signaling Pathway",82,"WP22",19,0.79,0.0666666666666667,0.0666666666666667,0.000601597866207179,0.999852323093054
"WP2249","Metastatic brain tumor",84,"WP2249",28,0.21,0.166666666666667,0.333333333333333,0.00291300857028192,0.999852323093054
"WP2261","Signaling Pathways in Glioblastoma",85,"WP2261",83,0.96,0.2375,0.25,1.45750470372243e-17,0.999852323093054
"WP2272","Pathogenic Escherichia coli infection",87,"WP2272",55,0.85,0.0851063829787234,0.191489361702128,4.18564642105688e-07,0.999852323093054
"WP2289","Drug Induction of Bile Acid Pathway",89,"WP2289",17,0.24,0.25,0.25,6.49286728094462e-06,0.999852323093054
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer",92,"WP2291",16,0.94,0.266666666666667,0.266666666666667,3.11005970071626e-15,0.999852323093054
"WP2324","AGE/RAGE pathway",95,"WP2324",66,0.95,0.142857142857143,0.206349206349206,1.45750470372243e-17,0.999852323093054
"WP2333","Trans-sulfuration pathway",98,"WP2333",10,1,0.2,0.2,7.49087453817701e-07,0.999852323093054
"WP2436","Dopamine metabolism",115,"WP2436",14,0.64,0.222222222222222,0.222222222222222,6.78665345557183e-11,0.999852323093054
"WP2447","Amyotrophic lateral sclerosis (ALS)",118,"WP2447",38,0.79,0.166666666666667,0.3,1.30274002920557e-12,0.999852323093054
"WP2485","NAD Biosynthesis II (from tryptophan)",122,"WP2485",8,0.75,0.166666666666667,0.166666666666667,1.2733947666864e-33,0.999852323093054
"WP2509","Nanoparticle triggered autophagic cell death",125,"WP2509",24,0.88,0.142857142857143,0.142857142857143,1.28737203377495e-08,0.999852323093054
"WP2513","Nanoparticle triggered regulated necrosis",126,"WP2513",12,0.92,0,0,0.795485118928105,0.999852323093054
"WP2526","PDGF Pathway",129,"WP2526",40,0.98,0.0769230769230769,0.128205128205128,1.21006371795151e-15,0.999852323093054
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS",134,"WP2572",74,0.78,0.275862068965517,0.310344827586207,4.81412003815079e-10,0.999852323093054
"WP2637","Structural Pathway of Interleukin 1 (IL-1)",142,"WP2637",50,0.98,0.142857142857143,0.204081632653061,1.21006371795151e-15,0.999852323093054
"WP2643","Nanoparticle-mediated activation of receptor signaling",144,"WP2643",29,0.97,0.178571428571429,0.214285714285714,0.00101315545629077,0.999852323093054
"WP268","Notch Signaling",147,"WP268",47,0.85,0.175,0.225,6.84417911248327e-08,0.999852323093054
"WP2805","exRNA mechanism of action and biogenesis",151,"WP2805",8,0.62,0.2,0.2,0.000217368536815086,0.999852323093054
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)",153,"WP2813",18,0.61,0.272727272727273,0.272727272727273,1.1219536394885e-16,0.999852323093054
"WP2853","Endoderm Differentiation",164,"WP2853",146,0.77,0.223214285714286,0.258928571428571,5.00019440781505e-25,0.999852323093054
"WP2857","Mesodermal Commitment Pathway",167,"WP2857",157,0.74,0.206896551724138,0.258620689655172,5.00019440781505e-25,0.999852323093054
"WP286","IL-3 Signaling Pathway",169,"WP286",49,0.9,0.159090909090909,0.204545454545455,1.21006371795151e-15,0.999852323093054
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer",170,"WP2864",54,0.93,0.16,0.28,4.12289297028431e-17,0.999852323093054
"WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer",172,"WP2868",5,1,0,0,0.999852323093054,0.999852323093054
"WP2873","Aryl Hydrocarbon Receptor Pathway",174,"WP2873",48,0.65,0.129032258064516,0.225806451612903,4.12289297028431e-17,0.999852323093054
"WP2875","Constitutive Androstane Receptor Pathway",176,"WP2875",32,0.53,0.176470588235294,0.235294117647059,2.9447393377517e-11,0.999852323093054
"WP2876","Pregnane X Receptor pathway",177,"WP2876",33,0.55,0.166666666666667,0.222222222222222,2.9447393377517e-11,0.999852323093054
"WP288","NLR Proteins",181,"WP288",9,0.89,0.125,0.125,0.00237947159212301,0.999852323093054
"WP2884","NRF2 pathway",184,"WP2884",146,0.66,0.1875,0.260416666666667,2.4987918295779e-23,0.999852323093054
"WP2889","Oxytocin signaling",185,"WP2889",4,0.5,0,0,0.999852323093054,0.999852323093054
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ",189,"WP2916",17,0.94,0.1875,0.3125,6.05665966147348e-07,0.999852323093054
"WP2942","DDX1 as a regulatory component of the Drosha microprocessor",190,"WP2942",9,0.67,0,0,0.990973876560315,0.999852323093054
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity",192,"WP299",35,0.46,0.25,0.25,1.20099662033474e-06,0.999852323093054
"WP304","Kit receptor signaling pathway",194,"WP304",60,0.98,0.169491525423729,0.220338983050847,1.45750470372243e-17,0.999852323093054
"WP311","Synthesis and Degradation of Ketone Bodies",196,"WP311",5,1,0.2,0.2,6.0888051023505e-05,0.999852323093054
"WP313","Signaling of Hepatocyte Growth Factor Receptor",197,"WP313",34,1,0.176470588235294,0.205882352941176,1.21006371795151e-15,0.999852323093054
"WP325","Triacylglyceride Synthesis",200,"WP325",26,0.54,0,0,0.999852323093054,0.999852323093054
"WP3300","Dual hijack model of Vif in HIV infection",206,"WP3300",9,0.67,0,0.166666666666667,0.118228105072828,0.999852323093054
"WP3302","eIF5A regulation in response to inhibition of the nuclear export system",208,"WP3302",4,0.75,0.333333333333333,0.333333333333333,0.00071352422837791,0.999852323093054
"WP3303","RAC1/PAK1/p38/MMP2 Pathway",209,"WP3303",69,0.9,0.225806451612903,0.274193548387097,3.11796204582401e-18,0.999852323093054
"WP357","Fatty Acid Biosynthesis",219,"WP357",22,0.91,0.2,0.2,1.10524321914212e-13,0.999852323093054
"WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma",224,"WP3593",9,0.78,0,0,0.999852323093054,0.999852323093054
"WP363","Wnt Signaling Pathway (Netpath)",237,"WP363",53,0.91,0.208333333333333,0.208333333333333,1.45750470372243e-17,0.999852323093054
"WP3630","NAD metabolism, sirtuins and aging",238,"WP3630",11,0.91,0.2,0.3,2.25748011539398e-08,0.999852323093054
"WP3634","Insulin signalling in human adipocytes (normal condition)",240,"WP3634",8,1,0.125,0.125,7.99040804992212e-20,0.999852323093054
"WP3635","Insulin signalling in human adipocytes (diabetic condition)",241,"WP3635",8,1,0.125,0.125,7.99040804992212e-20,0.999852323093054
"WP364","IL-6 signaling pathway",242,"WP364",43,0.95,0.24390243902439,0.24390243902439,1.55030261832076e-25,0.999852323093054
"WP3644","NAD+ metabolism",244,"WP3644",16,0.88,0.142857142857143,0.285714285714286,2.25748011539398e-08,0.999852323093054
"WP3645","NAD+ biosynthetic pathways",245,"WP3645",22,0.77,0.176470588235294,0.294117647058824,2.25748011539398e-08,0.999852323093054
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma",247,"WP3651",66,0.85,0.196428571428571,0.25,2.89465973850597e-12,0.999852323093054
"WP3655","Hypothetical Craniofacial Development Pathway",248,"WP3655",8,0.75,0.166666666666667,0.166666666666667,0.00407427421601939,0.999852323093054
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B",249,"WP3656",11,0.91,0.1,0.2,0.00279989180752429,0.999852323093054
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia",251,"WP3658",26,0.81,0.333333333333333,0.333333333333333,1.28160819617811e-23,0.999852323093054
"WP366","TGF-beta Signaling Pathway",252,"WP366",133,0.96,0.2109375,0.234375,1.4645909158934e-29,0.999852323093054
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease",255,"WP3668",25,0.92,0.217391304347826,0.304347826086957,1.91116166189054e-21,0.999852323093054
"WP3674","Tgif disruption of Shh signaling",258,"WP3674",9,0.44,0,0,0.999852323093054,0.999852323093054
"WP3676","BDNF-TrkB Signaling",259,"WP3676",34,0.88,0.166666666666667,0.2,1.84528135455106e-08,0.999852323093054
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation",262,"WP368",17,0.94,0.0625,0.0625,0.0167383786864681,0.999852323093054
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways",263,"WP3680",68,0.81,0.163636363636364,0.2,1.46702371634426e-15,0.999852323093054
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities",267,"WP3844",30,1,0.2,0.2,6.62772818839576e-10,0.999852323093054
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ",269,"WP3849",12,1,0.166666666666667,0.25,1.31802719833037e-09,0.999852323093054
"WP3851","TLR4 Signaling and Tolerance",271,"WP3851",30,0.83,0.08,0.16,1.55030261832076e-25,0.999852323093054
"WP3853","ERK Pathway in Huntington's Disease",272,"WP3853",15,0.87,0.230769230769231,0.307692307692308,1.84528135455106e-08,0.999852323093054
"WP3858","Toll-like Receptor Signaling related to MyD88",273,"WP3858",32,0.84,0,0.111111111111111,0.114048118916392,0.999852323093054
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection",275,"WP3863",62,0.81,0.14,0.22,1.21006371795151e-15,0.999852323093054
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway",276,"WP3865",61,0.84,0.137254901960784,0.235294117647059,3.37870774082303e-13,0.999852323093054
"WP3869","Cannabinoid receptor signaling",277,"WP3869",29,0.79,0.0869565217391304,0.130434782608696,3.92161302035637e-08,0.999852323093054
"WP3871","Valproic acid pathway",278,"WP3871",13,0.62,0.125,0.125,0.0102047891408715,0.999852323093054
"WP3874","Canonical and Non-Canonical TGF-B signaling",280,"WP3874",17,1,0.0588235294117647,0.235294117647059,1.47923810515956e-16,0.999852323093054
"WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway",283,"WP3877",19,0.74,0,0.214285714285714,0.0594386193019534,0.999852323093054
"WP3878","ATM Signaling Network in Development and Disease ",284,"WP3878",46,0.89,0.219512195121951,0.268292682926829,2.50026382158374e-16,0.999852323093054
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression",285,"WP3879",18,1,0.111111111111111,0.111111111111111,2.45237666239285e-07,0.999852323093054
"WP391","Mitochondrial Gene Expression",290,"WP391",20,0.8,0.125,0.1875,2.9447393377517e-11,0.999852323093054
"WP3924","Hfe effect on hepcidin production",292,"WP3924",7,0.57,0.25,0.25,0.00378182889135815,0.999852323093054
"WP3925","Amino Acid metabolism",293,"WP3925",91,0.73,0.166666666666667,0.227272727272727,2.58938282317479e-38,0.999852323093054
"WP3927","BMP Signaling Pathway in Eyelid Development",295,"WP3927",20,0.8,0.1875,0.25,1.1219536394885e-16,0.999852323093054
"WP3933","Kennedy pathway from Sphingolipids",300,"WP3933",15,0.8,0.0833333333333333,0.0833333333333333,0.000153115641692463,0.999852323093054
"WP3934","Leptin and adiponectin",301,"WP3934",10,0.8,0.125,0.125,1.13349503425421e-06,0.999852323093054
"WP3937","Microglia Pathogen Phagocytosis Pathway",303,"WP3937",40,0.9,0.0833333333333333,0.0833333333333333,1.57756315705304e-09,0.999852323093054
"WP3938","miR-222 in Exercise-Induced Cardiac Growth",304,"WP3938",4,1,0,0,0.999852323093054,0.999852323093054
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk",308,"WP3943",6,1,0.333333333333333,0.333333333333333,1.76304737966141e-10,0.999852323093054
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity",318,"WP3969",16,0.88,0.214285714285714,0.214285714285714,7.1806031181162e-15,0.999852323093054
"WP3971","Role of Osx and miRNAs in tooth development",319,"WP3971",36,0.28,0.2,0.2,1.74501293167954e-14,0.999852323093054
"WP3981","miRNA regulation of prostate cancer signaling pathways",321,"WP3981",59,0.54,0.15625,0.21875,1.28737203377495e-08,0.999852323093054
"WP399","Wnt Signaling Pathway and Pluripotency",323,"WP399",107,0.8,0.232558139534884,0.290697674418605,1.45750470372243e-17,0.999852323093054
"WP400","p38 MAPK Signaling Pathway",327,"WP400",34,0.97,0.181818181818182,0.242424242424242,4.7856489956754e-16,0.999852323093054
"WP4018","Pathways in clear cell renal cell carcinoma",330,"WP4018",87,0.91,0.164556962025316,0.189873417721519,1.10524321914212e-13,0.999852323093054
"WP405","Eukaryotic Transcription Initiation",334,"WP405",43,0.95,0.0975609756097561,0.146341463414634,2.41984712730741e-07,0.999852323093054
"WP410","Exercise-induced Circadian Regulation",336,"WP410",49,0.9,0.272727272727273,0.295454545454545,1.86144948015588e-42,0.999852323093054
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway",338,"WP4136",42,0.71,0.0666666666666667,0.166666666666667,1.55030261832076e-25,0.999852323093054
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling",339,"WP4141",22,0.86,0.263157894736842,0.263157894736842,3.87043570690072e-12,0.999852323093054
"WP4146","Macrophage markers",341,"WP4146",9,1,0,0.111111111111111,0.21102640351702,0.999852323093054
"WP4150","Wnt Signaling in Kidney Disease",345,"WP4150",39,0.69,0.222222222222222,0.222222222222222,8.33920870140507e-09,0.999852323093054
"WP4155","Endometrial cancer",347,"WP4155",63,0.94,0.152542372881356,0.220338983050847,1.04633266994318e-15,0.999852323093054
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging",352,"WP4186",6,1,0.333333333333333,0.333333333333333,2.25748011539398e-08,0.999852323093054
"WP4189","Mevalonate arm of cholesterol biosynthesis pathway with inhibitors",353,"WP4189",2,1,0,0,0.999852323093054,0.999852323093054
"WP4197","The human immune response to tuberculosis",356,"WP4197",23,1,0.130434782608696,0.130434782608696,0.000341914298724229,0.999852323093054
"WP4205","MET in type 1 papillary renal cell carcinoma",358,"WP4205",59,0.88,0.115384615384615,0.173076923076923,3.90142119029615e-06,0.999852323093054
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway",359,"WP4206",20,0.95,0.105263157894737,0.210526315789474,2.03101031117154e-10,0.999852323093054
"WP4210","Tryptophan catabolism leading to NAD+ production",360,"WP4210",16,0.69,0.0909090909090909,0.0909090909090909,1.2733947666864e-33,0.999852323093054
"WP4217","Ebola Virus Pathway on Host",363,"WP4217",132,0.89,0.135593220338983,0.186440677966102,7.15702783093164e-17,0.999852323093054
"WP422","MAPK Cascade",364,"WP422",33,1,0.212121212121212,0.272727272727273,1.06179313771239e-06,0.999852323093054
"WP4223","Ras Signaling",367,"WP4223",186,0.76,0.204225352112676,0.26056338028169,2.6982385516733e-21,0.999852323093054
"WP4236","Disorders of the Krebs cycle",372,"WP4236",7,1,0.142857142857143,0.142857142857143,0.000542153786249434,0.999852323093054
"WP4239","Epithelial to mesenchymal transition in colorectal cancer",373,"WP4239",164,0.78,0.1953125,0.2578125,5.10653311534479e-29,0.999852323093054
"WP4241","Type 2 papillary renal cell carcinoma",375,"WP4241",36,0.83,0.133333333333333,0.166666666666667,6.62772818839576e-10,0.999852323093054
"WP4255","Non-small cell lung cancer",377,"WP4255",72,0.93,0.149253731343284,0.238805970149254,1.45750470372243e-17,0.999852323093054
"WP4263","Pancreatic adenocarcinoma pathway",381,"WP4263",89,0.96,0.141176470588235,0.211764705882353,1.47923810515956e-16,0.999852323093054
"WP4271","Vitamin B12 Disorders",383,"WP4271",13,0.69,0,0.222222222222222,0.105553301023444,0.999852323093054
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders",389,"WP4292",11,0.82,0.222222222222222,0.222222222222222,5.6500805039415e-14,0.999852323093054
"WP430","Statin Pathway",394,"WP430",33,0.45,0.133333333333333,0.266666666666667,0.00133659811986492,0.999852323093054
"WP4313","Ferroptosis",399,"WP4313",40,0.9,0.138888888888889,0.194444444444444,1.14291084616521e-05,0.999852323093054
"WP4331","Neovascularisation processes",404,"WP4331",37,1,0.189189189189189,0.27027027027027,3.37870774082303e-13,0.999852323093054
"WP4352","Ciliary landscape",409,"WP4352",220,0.9,0.137055837563452,0.208121827411168,4.19419091059679e-15,0.999852323093054
"WP4389","Bile Acids synthesis and enterohepatic circulation ",413,"WP4389",13,0.38,0,0.2,0.191601747736878,0.999852323093054
"WP4396","Nonalcoholic fatty liver disease",414,"WP4396",160,0.84,0.133333333333333,0.207407407407407,1.55030261832076e-25,0.999852323093054
"WP4397","Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors",415,"WP4397",3,0.67,0,0,0.999852323093054,0.999852323093054
"WP4478","LTF danger signal response pathway",419,"WP4478",20,0.7,0.0714285714285714,0.214285714285714,1.55030261832076e-25,0.999852323093054
"WP4479","Supression of HMGB1 mediated inflammation by THBD",420,"WP4479",9,1,0,0.111111111111111,0.452666162731714,0.999852323093054
"WP4494","Selective expression of chemokine receptors during T-cell polarization",427,"WP4494",29,0.55,0.0625,0.125,0.00407427421601939,0.999852323093054
"WP4496","Signal transduction through IL1R",429,"WP4496",35,0.86,0.133333333333333,0.233333333333333,1.55030261832076e-25,0.999852323093054
"WP4504","Cysteine and methionine catabolism",431,"WP4504",15,0.87,0.153846153846154,0.153846153846154,5.6500805039415e-14,0.999852323093054
"WP4506","Tyrosine Metabolism",432,"WP4506",4,0.25,0,0,0.999852323093054,0.999852323093054
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases",434,"WP4518",10,0.5,0.2,0.2,0.000377573164229441,0.999852323093054
"WP4521","Glycosylation and related congenital defects",436,"WP4521",25,1,0.12,0.16,1.02496252421453e-08,0.999852323093054
"WP4523","Classical pathway of steroidogenesis, including diseases",438,"WP4523",16,0.31,0,0.2,0.273007477872406,0.999852323093054
"WP4524","The alternative pathway of fetal androgen synthesis",439,"WP4524",12,0.33,0.25,0.25,2.8033361067803e-09,0.999852323093054
"WP453","Inflammatory Response Pathway",440,"WP453",33,0.67,0.0909090909090909,0.181818181818182,0.000442098767154395,0.999852323093054
"WP4532","Intraflagellar transport proteins binding to dynein",441,"WP4532",27,0.93,0.08,0.16,0.00558066527342552,0.999852323093054
"WP4533","Transcription co-factors SKI and SKIL protein partners",442,"WP4533",18,1,0.166666666666667,0.277777777777778,1.54778757247964e-06,0.999852323093054
"WP4536","Genes related to primary cilium development (based on CRISPR)",445,"WP4536",103,0.92,0.105263157894737,0.189473684210526,8.57900007846234e-13,0.999852323093054
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder",448,"WP4539",51,0.76,0.256410256410256,0.256410256410256,9.26038985479124e-09,0.999852323093054
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions",451,"WP4542",36,0.86,0.161290322580645,0.258064516129032,1.54778757247964e-06,0.999852323093054
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma",455,"WP4553",38,0.29,0.181818181818182,0.272727272727273,3.04356671038824e-07,0.999852323093054
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment",457,"WP4559",40,0.6,0.125,0.25,1.47923810515956e-16,0.999852323093054
"WP4561","Cell migration and invasion through p75NTR",459,"WP4561",31,0.9,0.214285714285714,0.285714285714286,3.88351886854851e-13,0.999852323093054
"WP4564","Neural Crest Cell Migration during Development",461,"WP4564",41,0.8,0.151515151515152,0.242424242424242,1.21006371795151e-15,0.999852323093054
"WP4565","Neural Crest Cell Migration in Cancer",462,"WP4565",44,0.82,0.166666666666667,0.25,1.21006371795151e-15,0.999852323093054
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway",465,"WP4577",44,0.98,0.0930232558139535,0.116279069767442,0.000303680199088757,0.999852323093054
"WP4595","Urea cycle and associated pathways",472,"WP4595",21,0.76,0.25,0.3125,1.21134935033961e-14,0.999852323093054
"WP4629","Computational Model of Aerobic Glycolysis",473,"WP4629",12,0.92,0.181818181818182,0.181818181818182,1.94971495989183e-05,0.999852323093054
"WP4655","Cytosolic DNA-sensing pathway",475,"WP4655",76,0.72,0.109090909090909,0.145454545454545,1.55030261832076e-25,0.999852323093054
"WP4659","Gastrin Signaling Pathway",479,"WP4659",114,0.92,0.180952380952381,0.238095238095238,4.7856489956754e-16,0.999852323093054
"WP4674","Head and Neck Squamous Cell Carcinoma",484,"WP4674",70,0.94,0.121212121212121,0.166666666666667,1.47923810515956e-16,0.999852323093054
"WP4685","Melanoma",485,"WP4685",68,0.93,0.174603174603175,0.26984126984127,1.21006371795151e-15,0.999852323093054
"WP47","Hedgehog Signaling Pathway Netpath",487,"WP47",16,0.75,0.0833333333333333,0.25,0.0317273821116764,0.999852323093054
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing",488,"WP4705",16,0.81,0.153846153846154,0.153846153846154,1.16208386478435e-12,0.999852323093054
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)",489,"WP4718",47,0.87,0.219512195121951,0.268292682926829,1.16398114740138e-08,0.999852323093054
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)",492,"WP4721",29,0.69,0.2,0.25,4.45382103461115e-22,0.999852323093054
"WP4722","Glycerolipids and Glycerophospholipids",493,"WP4722",24,0.75,0.0555555555555556,0.0555555555555556,0.000153115641692463,0.999852323093054
"WP4723","Omega-3/Omega-6 FA synthesis",494,"WP4723",15,0.73,0,0.0909090909090909,0.296626199889639,0.999852323093054
"WP4726","Sphingolipid Metabolism (integrated pathway)",497,"WP4726",25,0.84,0.19047619047619,0.238095238095238,1.3073328528498e-06,0.999852323093054
"WP4742","Ketogenesis and Ketolysis",499,"WP4742",8,1,0.125,0.125,6.0888051023505e-05,0.999852323093054
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism",500,"WP4746",95,0.69,0.227272727272727,0.272727272727273,2.44977316588364e-24,0.999852323093054
"WP4747","Netrin-UNC5B signaling Pathway",501,"WP4747",52,0.85,0.181818181818182,0.272727272727273,2.5665992363522e-08,0.999852323093054
"WP4751","HIPK2 in kidney fibrosis",502,"WP4751",2,1,0,0,0.999852323093054,0.999852323093054
"WP4753","Nucleotide Excision Repair",504,"WP4753",44,0.98,0.255813953488372,0.27906976744186,3.57124737003596e-13,0.999852323093054
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation",509,"WP4767",27,0.89,0.166666666666667,0.25,1.60955895014834e-18,0.999852323093054
"WP477","Cytoplasmic Ribosomal Proteins",510,"WP477",91,0.93,0.129411764705882,0.164705882352941,8.56966962716958e-10,0.999852323093054
"WP4792","Purine metabolism",511,"WP4792",13,0.85,0.272727272727273,0.272727272727273,3.92279863878209e-05,0.999852323093054
"WP481","Insulin Signaling",512,"WP481",161,0.93,0.186666666666667,0.246666666666667,2.30627807010563e-26,0.999852323093054
"WP49","IL-2 Signaling Pathway",513,"WP49",42,0.98,0.195121951219512,0.24390243902439,1.21006371795151e-15,0.999852323093054
"WP496","Steroid Biosynthesis",514,"WP496",10,0.4,0,0.25,0.386085732506969,0.999852323093054
"WP500","Glycogen Synthesis and Degradation",516,"WP500",40,0.9,0.138888888888889,0.194444444444444,9.51262628208688e-25,0.999852323093054
"WP51","Regulation of Actin Cytoskeleton",518,"WP51",151,0.77,0.213675213675214,0.273504273504274,1.04633266994318e-15,0.999852323093054
"WP521","Amino acid conjugation of benzoic acid",520,"WP521",5,0.2,0,0,0.999852323093054,0.999852323093054
"WP524","G13 Signaling Pathway",521,"WP524",41,0.85,0.2,0.2,6.63243812483213e-11,0.999852323093054
"WP528","Acetylcholine Synthesis",522,"WP528",7,0.57,0,0,0.999852323093054,0.999852323093054
"WP534","Glycolysis and Gluconeogenesis",526,"WP534",45,0.73,0.121212121212121,0.121212121212121,7.99040804992212e-20,0.999852323093054
"WP560","TGF-beta Receptor Signaling",532,"WP560",58,0.79,0.217391304347826,0.260869565217391,1.47923810515956e-16,0.999852323093054
"WP581","EPO Receptor Signaling",535,"WP581",26,0.96,0.08,0.08,0.000601597866207179,0.999852323093054
"WP585","Interferon type I signaling pathways",536,"WP585",55,0.95,0.173076923076923,0.230769230769231,9.45573250233619e-09,0.999852323093054
"WP61","Notch Signaling Pathway Netpath",537,"WP61",63,0.9,0.157894736842105,0.280701754385965,4.8712821556021e-23,0.999852323093054
"WP615","Senescence and Autophagy in Cancer",538,"WP615",108,0.86,0.193548387096774,0.258064516129032,1.55030261832076e-25,0.999852323093054
"WP623","Oxidative phosphorylation",540,"WP623",62,0.6,0,0.0540540540540541,0.0626324188453113,0.999852323093054
"WP673","ErbB Signaling Pathway",542,"WP673",91,0.89,0.209876543209877,0.259259259259259,3.46021469111041e-20,0.999852323093054
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase",543,"WP678",7,0.71,0.2,0.2,4.43345799464762e-09,0.999852323093054
"WP688","Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)",544,"WP688",5,0.6,0,0,0.999852323093054,0.999852323093054
"WP690","Polyol Pathway",546,"WP690",4,0.75,0,0,0.855645046418417,0.999852323093054
"WP692","Sulfation Biotransformation Reaction",548,"WP692",19,0.32,0,0,0.999852323093054,0.999852323093054
"WP694","Arylamine metabolism",549,"WP694",6,0.33,0,0,0.999852323093054,0.999852323093054
"WP696","Benzo(a)pyrene metabolism",550,"WP696",9,0.78,0,0.142857142857143,0.186101834726753,0.999852323093054
"WP697","Estrogen metabolism",551,"WP697",19,0.47,0,0,0.999852323093054,0.999852323093054
"WP698","Glucuronidation",552,"WP698",26,0.35,0.222222222222222,0.222222222222222,2.6913627863713e-23,0.999852323093054
"WP699","Aflatoxin B1 metabolism",553,"WP699",7,0.43,0,0,0.999852323093054,0.999852323093054
"WP702","Metapathway biotransformation Phase I and II",554,"WP702",188,0.48,0.133333333333333,0.188888888888889,2.4987918295779e-23,0.999852323093054
"WP710","DNA Damage Response (only ATM dependent)",558,"WP710",115,0.87,0.13,0.21,1.57756315705304e-09,0.999852323093054
"WP712","Estrogen signaling pathway",559,"WP712",23,0.91,0.19047619047619,0.333333333333333,1.21006371795151e-15,0.999852323093054
"WP716","Vitamin A and Carotenoid Metabolism",560,"WP716",44,0.5,0.181818181818182,0.272727272727273,9.28054409606823e-14,0.999852323093054
"WP733","Serotonin Receptor 2 and STAT3 Signaling",563,"WP733",4,0.75,0.333333333333333,0.333333333333333,0.0212542319346549,0.999852323093054
"WP75","Toll-like Receptor Signaling Pathway",565,"WP75",104,0.75,0.0897435897435897,0.179487179487179,1.55030261832076e-25,0.999852323093054
"WP78","TCA Cycle (aka Krebs or citric acid cycle)",566,"WP78",18,1,0,0.0555555555555556,0.345480440691871,0.999852323093054
"WP80","Nucleotide GPCRs",567,"WP80",11,0.73,0,0,0.999852323093054,0.999852323093054
"WP127","IL-5 Signaling Pathway",7,"WP127",40,0.95,0.236842105263158,0.263157894736842,1.21006371795151e-15,0.999852323093054
"WP138","Androgen receptor signaling pathway",11,"WP138",91,0.9,0.195121951219512,0.25609756097561,1.33825325438479e-13,0.999852323093054
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation",16,"WP1425",12,0.83,0.1,0.2,0.0044135122745415,0.999852323093054
"WP1559","TFs Regulate miRNAs related to cardiac hypertrophy",34,"WP1559",12,0.58,0,0.142857142857143,0.452666162731714,0.999852323093054
"WP1946","Cori Cycle",53,"WP1946",17,0.82,0.142857142857143,0.142857142857143,7.99040804992212e-20,0.999852323093054
"WP2034","Leptin signaling pathway",69,"WP2034",76,0.99,0.213333333333333,0.266666666666667,6.63243812483213e-11,0.999852323093054
"WP2290","RalA downstream regulated genes",91,"WP2290",12,0.92,0.181818181818182,0.181818181818182,1.57756315705304e-09,0.999852323093054
"WP23","B Cell Receptor Signaling Pathway",93,"WP23",98,0.94,0.184782608695652,0.260869565217391,1.45750470372243e-17,0.999852323093054
"WP2328","Allograft Rejection",96,"WP2328",90,0.69,0.17741935483871,0.209677419354839,2.86780567028817e-25,0.999852323093054
"WP2332","Interleukin-11 Signaling Pathway",97,"WP2332",44,0.91,0.225,0.25,3.51846221320189e-12,0.999852323093054
"WP2795","Cardiac Hypertrophic Response",149,"WP2795",57,0.89,0.196078431372549,0.254901960784314,2.08918249834541e-15,0.999852323093054
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling",233,"WP3614",37,0.89,0.181818181818182,0.242424242424242,3.51846221320189e-12,0.999852323093054
"WP3891","Benzene metabolism",287,"WP3891",6,0.5,0,0,0.999852323093054,0.999852323093054
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway",291,"WP3915",132,0.89,0.136752136752137,0.170940170940171,7.99040804992212e-20,0.999852323093054
"WP3926","ApoE and miR-146 in inflammation and atherosclerosis",294,"WP3926",9,0.89,0,0.125,0.114048118916392,0.999852323093054
"WP404","Nucleotide Metabolism",333,"WP404",19,0.95,0.166666666666667,0.166666666666667,3.57124737003596e-13,0.999852323093054
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ",362,"WP4216",74,0.96,0.211267605633803,0.267605633802817,1.47923810515956e-16,0.999852323093054
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1",382,"WP4269",10,0.9,0.111111111111111,0.333333333333333,7.45368111307164e-07,0.999852323093054
"WP4288","MTHFR deficiency",387,"WP4288",27,0.7,0.315789473684211,0.315789473684211,1.69249742410717e-08,0.999852323093054
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells",396,"WP4301",18,1,0.166666666666667,0.222222222222222,9.01134422889796e-05,0.999852323093054
"WP4324","Mitochondrial complex I assembly model OXPHOS system",402,"WP4324",56,0.8,0,0.0222222222222222,0.0626324188453113,0.999852323093054
"WP4329","miRNAs involvement in the immune response in sepsis",403,"WP4329",64,0.5,0.0625,0.1875,1.55030261832076e-25,0.999852323093054
"WP438","Non-homologous end joining",412,"WP438",11,0.91,0.1,0.1,0.00934439177317729,0.999852323093054
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ",428,"WP4495",12,0.92,0.181818181818182,0.272727272727273,1.55030261832076e-25,0.999852323093054
"WP4507","Molybdenum cofactor (Moco) biosynthesis",433,"WP4507",7,1,0.142857142857143,0.285714285714286,3.39506009152496e-24,0.999852323093054
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms",443,"WP4534",48,0.92,0.159090909090909,0.272727272727273,8.80436312071741e-23,0.999852323093054
"WP4558","Overview of interferons-mediated signaling pathway",456,"WP4558",37,0.38,0.214285714285714,0.214285714285714,0.000341914298724229,0.999852323093054
"WP4566","Translation inhibitors in chronically activated PDGFRA cells",463,"WP4566",48,0.94,0.177777777777778,0.2,8.56966962716958e-10,0.999852323093054
"WP4582","Cancer immunotherapy by CTLA4 blockade",466,"WP4582",15,0.8,0,0,0.835939678356078,0.999852323093054
"WP4656","Joubert Syndrome",476,"WP4656",77,0.9,0.130434782608696,0.217391304347826,4.67701164770016e-10,0.999852323093054
"WP501","GPCRs, Class C Metabotropic glutamate, pheromone",517,"WP501",16,0.31,0,0,0.999852323093054,0.999852323093054
"WP619","Type II interferon signaling (IFNG)",539,"WP619",37,0.84,0.193548387096774,0.258064516129032,9.44618578094348e-09,0.999852323093054
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway",545,"WP69",91,0.9,0.0975609756097561,0.182926829268293,1.55030261832076e-25,0.999852323093054
"WP691","Tamoxifen metabolism",547,"WP691",21,0.24,0.2,0.2,0.0372370714105519,0.999852323093054
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling",562,"WP732",20,0.75,0.2,0.266666666666667,6.52294438984146e-17,0.999852323093054
"WP1981","Thyroxine (Thyroid Hormone) Production",57,"WP1981",6,0,NA,NA,NA,NA
"WP2491","Diclofenac Metabolic Pathway",123,"WP2491",4,0,NA,NA,NA,NA
"WP2536","Colchicine Metabolic Pathway",131,"WP2536",1,0,NA,NA,NA,NA
"WP2596","Gastric acid production",137,"WP2596",7,0,NA,NA,NA,NA
"WP2597","Secretion of Hydrochloric Acid in Parietal Cells",138,"WP2597",5,0,NA,NA,NA,NA
"WP2640","Aripiprazole Metabolic Pathway",143,"WP2640",2,0,NA,NA,NA,NA
"WP2646","Lidocaine metabolism",146,"WP2646",2,0,NA,NA,NA,NA
"WP2816","Felbamate Metabolism",156,"WP2816",2,0,NA,NA,NA,NA
"WP3627","Gut-Liver Indole Metabolism ",236,"WP3627",1,0,NA,NA,NA,NA
"WP3666","Metabolism of Dichloroethylene by CYP450",254,"WP3666",1,0,NA,NA,NA,NA
"WP4174","Metabolism of Tetrahydrocannabinol (THC)",351,"WP4174",2,0,NA,NA,NA,NA
"WP4194","Hormonal control of Pubertal Growth Spurt",355,"WP4194",2,0,NA,NA,NA,NA
"WP4233","Acrylamide Biotransformation and Exposure Biomarkers",371,"WP4233",1,0,NA,NA,NA,NA
"WP661","Glucose Homeostasis",541,"WP661",1,0,NA,NA,NA,NA
1 set_id name ID Name Size Coverage TDP.bound TDP.estimate SC.adjP Comp.adjP
2 WP1600 Nicotine Metabolism 38 WP1600 6 0.17 1 1 3.39506009152496e-24 3.39506009152496e-24
3 WP2276 Glial Cell Differentiation 88 WP2276 8 0.62 0.4 0.4 7.83386153710323e-26 5.70447887867626e-23
4 WP4030 SCFA and skeletal muscle substrate metabolism 332 WP4030 6 0.33 0.5 0.5 7.99040804992212e-20 7.99040804992212e-20
5 WP334 GPCRs, Class B Secretin-like 210 WP334 24 0.17 0.5 0.5 3.06579274689702e-21 1.60955895014834e-18
6 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 60 WP1991 13 0.69 0.888888888888889 1 5.37258163429194e-24 1.16900918682e-14
7 WP206 Fatty Acid Omega Oxidation 76 WP206 15 0.33 0.6 0.8 2.94021006969881e-38 1.31928124608757e-14
8 WP3299 let-7 inhibition of ES cell reprogramming 205 WP3299 15 0.33 0.6 0.6 1.69191698398203e-15 1.74501293167954e-14
9 WP2023 Cell Differentiation - Index expanded 66 WP2023 50 0.22 0.727272727272727 0.727272727272727 4.7856489956754e-16 2.33586928012365e-14
10 WP2029 Cell Differentiation - Index 67 WP2029 42 0.14 0.833333333333333 0.833333333333333 4.7856489956754e-16 2.33586928012365e-14
11 WP2366 Butyrate-induced histone acetylation 105 WP2366 2 1 0.5 0.5 1.10524321914212e-13 1.10524321914212e-13
12 WP3297 EV release from cardiac cells and their functional effects 203 WP3297 9 0.44 0.75 0.75 3.05550468161626e-32 3.37870774082303e-13
13 WP554 ACE Inhibitor Pathway 530 WP554 17 0.65 0.545454545454545 0.545454545454545 3.79036700534385e-25 5.54255202240522e-13
14 WP4284 Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer 385 WP4284 5 0.4 0.5 0.5 2.90591396510707e-11 2.90591396510707e-11
15 WP2361 Gastric Cancer Network 1 103 WP2361 29 0.76 0.727272727272727 0.727272727272727 3.61848623532521e-17 1.04514067941364e-10
16 WP3944 Serotonin and anxiety-related events 309 WP3944 13 0.46 0.666666666666667 0.666666666666667 1.45750470372243e-17 3.26510400891469e-09
17 WP3947 Serotonin and anxiety 311 WP3947 17 0.41 0.428571428571429 0.428571428571429 1.45750470372243e-17 3.26510400891469e-09
18 WP1438 Influenza A virus infection 20 WP1438 2 0.5 1 1 1.28737203377495e-08 1.28737203377495e-08
19 WP383 Striated Muscle Contraction Pathway 265 WP383 38 0.61 0.565217391304348 0.652173913043478 1.03667354058147e-21 1.30607861950122e-08
20 WP2542 Sulindac Metabolic Pathway 133 WP2542 5 0.8 0.5 0.75 4.35964063989166e-11 2.5564111779557e-08
21 WP4222 Phosphodiesterases in neuronal function 366 WP4222 55 0.56 0.419354838709677 0.483870967741935 1.11151548949677e-22 3.51064709129753e-08
22 WP2943 Hypoxia-mediated EMT and Stemness 191 WP2943 2 1 0.5 0.5 1.87433487284931e-07 1.87433487284931e-07
23 WP2874 Liver X Receptor Pathway 175 WP2874 10 0.5 0.4 0.4 9.83107916736652e-08 2.35055233649832e-07
24 WP466 DNA Replication 480 WP466 42 0.98 0.634146341463415 0.75609756097561 3.91911842678923e-14 4.20885218710584e-07
25 WP545 Complement Activation 528 WP545 22 0.68 0.466666666666667 0.466666666666667 3.75341311013175e-54 6.35126956702113e-07
26 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition 374 WP4240 16 0.94 0.533333333333333 0.533333333333333 4.41152154021936e-12 6.65380602412947e-07
27 WP4300 Extracellular vesicles in the crosstalk of cardiac cells 395 WP4300 28 0.61 0.411764705882353 0.588235294117647 1.55030261832076e-25 8.80494600850642e-07
28 WP531 DNA Mismatch Repair 525 WP531 22 0.95 0.523809523809524 0.571428571428571 3.57124737003596e-13 1.25145166671192e-06
29 WP4589 Major receptors targeted by epinephrine and norepinephrine 471 WP4589 15 0.73 0.636363636363636 0.636363636363636 1.11151548949677e-22 2.66815064645758e-06
30 WP4760 PKC-gamma calcium signaling pathway in ataxia 508 WP4760 22 0.55 0.416666666666667 0.583333333333333 6.52294438984146e-17 2.70719651941471e-06
31 WP4191 Caloric restriction and aging 354 WP4191 8 1 0.375 0.375 2.9447393377517e-11 3.80469322236512e-06
32 WP2446 Retinoblastoma Gene in Cancer 117 WP2446 88 0.98 0.546511627906977 0.593023255813954 1.96366351804733e-14 4.24785596200959e-06
33 WP1992 Genes targeted by miRNAs in adipocytes 61 WP1992 19 0.53 0.5 0.5 2.33586928012365e-14 8.49856030430427e-06
34 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma 406 WP4337 17 0.76 0.538461538461538 0.615384615384615 1.55030261832076e-25 9.36831691097847e-06
35 WP2645 Heroin metabolism 145 WP2645 3 0.67 0.5 1 1.87627142351219e-05 1.87627142351219e-05
36 WP2826 Cocaine metabolism 158 WP2826 4 0.5 0.5 1 1.87627142351219e-05 1.87627142351219e-05
37 WP1602 Nicotine Activity on Dopaminergic Neurons 40 WP1602 22 0.5 0.636363636363636 0.818181818181818 2.50026382158374e-16 2.24952453555091e-05
38 WP4545 Oxysterols derived from cholesterol 452 WP4545 18 0.56 0.6 0.6 1.46780086933461e-09 2.36116814219851e-05
39 WP45 G1 to S cell cycle control 430 WP45 64 0.95 0.491803278688525 0.573770491803279 3.91911842678923e-14 2.89588011644963e-05
40 WP1495 Glycine Metabolism 24 WP1495 4 0.75 0.666666666666667 0.666666666666667 7.32732034249336e-10 2.91348117795513e-05
41 WP2879 Farnesoid X Receptor Pathway 180 WP2879 19 0.37 0.428571428571429 0.428571428571429 1.03671457774015e-11 0.000129931976156264
42 WP34 Ovarian Infertility Genes 211 WP34 32 0.53 0.411764705882353 0.411764705882353 8.1728342950092e-20 0.000152471085336278
43 WP516 Hypertrophy Model 519 WP516 20 0.75 0.466666666666667 0.533333333333333 1.73723649603814e-29 0.000166791537749366
44 WP247 Small Ligand GPCRs 121 WP247 19 0.53 0.6 0.8 3.77273931182897e-18 0.000182717661150266
45 WP2363 Gastric Cancer Network 2 104 WP2363 33 0.88 0.448275862068966 0.448275862068966 1.12863099668653e-15 0.000185246692246443
46 WP170 Nuclear Receptors 44 WP170 39 0.74 0.413793103448276 0.413793103448276 5.53853655041636e-45 0.000204208460415242
47 WP3996 Ethanol effects on histone modifications 325 WP3996 31 0.9 0.428571428571429 0.5 2.94021006969881e-38 0.000238758692258098
48 WP4400 FABP4 in ovarian cancer 417 WP4400 2 0.5 1 1 0.000245357066905715 0.000245357066905715
49 WP58 Monoamine GPCRs 534 WP58 33 0.15 0.6 0.6 2.66815064645758e-06 0.000266280491622695
50 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 261 WP3679 13 0.69 0.444444444444444 0.555555555555556 6.52294438984146e-17 0.000315427333264674
51 WP2338 miRNA Biogenesis 99 WP2338 8 0.75 0.5 0.5 5.52094234656009e-11 0.000633704399420972
52 WP1455 Serotonin Transporter Activity 22 WP1455 11 0.73 0.375 0.5 5.50097841431123e-07 0.000698192443745329
53 WP4016 DNA IR-damage and cellular response via ATR 329 WP4016 83 0.9 0.413333333333333 0.466666666666667 3.1984443894539e-16 0.000704575375419051
54 WP179 Cell Cycle 48 WP179 122 0.94 0.434782608695652 0.48695652173913 3.91911842678923e-14 0.000860192369254168
55 WP2848 Differentiation Pathway 162 WP2848 48 0.54 0.461538461538462 0.538461538461538 1.55030261832076e-25 0.000900218402911242
56 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) 155 WP2815 10 1 0.5 0.7 3.47598200773578e-10 0.000979886474579196
57 WP322 Osteoblast Signaling 199 WP322 14 0.5 0.428571428571429 0.428571428571429 1.60955895014834e-18 0.00122105800992755
58 WP4583 Biomarkers for urea cycle disorders 467 WP4583 12 0.67 0.375 0.375 1.05891161032475e-42 0.00125836568297114
59 WP3893 Development and heterogeneity of the ILC family 289 WP3893 32 0.56 0.5 0.555555555555556 1.55030261832076e-25 0.00137922281926359
60 WP2406 Cardiac Progenitor Differentiation 112 WP2406 53 0.57 0.466666666666667 0.5 5.00019440781505e-25 0.0019450999028179
61 WP558 Complement and Coagulation Cascades 531 WP558 59 0.66 0.41025641025641 0.487179487179487 3.75341311013175e-54 0.00204133415581446
62 WP2516 ATM Signaling Pathway 127 WP2516 40 0.92 0.405405405405405 0.459459459459459 6.96540853859659e-18 0.00226170199642674
63 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 282 WP3876 13 0.85 0.454545454545455 0.454545454545455 1.1219536394885e-16 0.00287452439577986
64 WP1545 miRNAs involved in DNA damage response 33 WP1545 50 0.28 0.357142857142857 0.428571428571429 1.33825325438479e-13 0.00291300857028192
65 WP3591 Sleep regulation 223 WP3591 38 0.34 0.461538461538462 0.538461538461538 1.55030261832076e-25 0.00298637777295038
66 WP2855 Dopaminergic Neurogenesis 166 WP2855 30 0.33 0.4 0.6 8.1921343985721e-23 0.00300186445388684
67 WP497 Urea cycle and metabolism of amino groups 515 WP497 21 0.76 0.375 0.4375 1.21134935033961e-14 0.00350987947486594
68 WP3407 FTO Obesity Variant Mechanism 212 WP3407 8 0.88 0.428571428571429 0.428571428571429 2.9447393377517e-11 0.00376777148807062
69 WP289 Myometrial Relaxation and Contraction Pathways 186 WP289 158 0.76 0.391666666666667 0.466666666666667 4.72920713559152e-27 0.00465022180500277
70 WP1530 miRNA Regulation of DNA Damage Response 27 WP1530 93 0.69 0.375 0.453125 2.50026382158374e-16 0.00482551043459127
71 WP4149 White fat cell differentiation 344 WP4149 33 0.91 0.4 0.433333333333333 3.05550468161626e-32 0.00497520122591071
72 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) 154 WP2814 13 0.92 0.5 0.5 8.1728342950092e-20 0.00569300599773054
73 WP1603 Nicotine Activity on Chromaffin Cells 41 WP1603 4 0.25 1 1 0.00581825930604642 0.00581825930604642
74 WP4698 Vitamin D-sensitive calcium signaling in depression 486 WP4698 41 0.54 0.363636363636364 0.5 6.52294438984146e-17 0.00581825930604642
75 WP1971 Integrated Cancer Pathway 56 WP1971 46 0.93 0.372093023255814 0.418604651162791 1.47590569356761e-12 0.00623426422936051
76 WP4224 Purine metabolism and related disorders 368 WP4224 22 0.86 0.368421052631579 0.421052631578947 3.39506009152496e-24 0.00660624701596271
77 WP4259 Disorders of Folate Metabolism and Transport 379 WP4259 13 0.85 0.454545454545455 0.454545454545455 7.32732034249336e-10 0.00660624701596271
78 WP1601 Fluoropyrimidine Activity 39 WP1601 34 0.82 0.392857142857143 0.5 7.38854762906026e-09 0.00668550277003425
79 WP2806 Human Complement System 152 WP2806 99 0.64 0.349206349206349 0.428571428571429 3.75341311013175e-54 0.00703640980157322
80 WP707 DNA Damage Response 557 WP707 69 0.9 0.370967741935484 0.451612903225806 2.50026382158374e-16 0.00934439177317729
81 WP2895 Differentiation of white and brown adipocyte 187 WP2895 25 0.72 0.388888888888889 0.388888888888889 4.791051754563e-15 0.00971361957709086
82 WP1995 Effects of Nitric Oxide 62 WP1995 8 0.5 0.5 0.75 3.39506009152496e-24 0.0112147264561884
83 WP136 Phase I biotransformations, non P450 10 WP136 8 0.62 0.4 0.6 1.87627142351219e-05 0.0123569322150726
84 WP536 Calcium Regulation in the Cardiac Cell 527 WP536 152 0.7 0.355140186915888 0.429906542056075 7.92756655687513e-25 0.0169432049684982
85 WP35 G Protein Signaling Pathways 216 WP35 97 0.78 0.355263157894737 0.434210526315789 1.11151548949677e-22 0.0169866528793556
86 WP241 One Carbon Metabolism 113 WP241 31 0.81 0.4 0.48 7.32732034249336e-10 0.0170103318686093
87 WP4571 Urea cycle and related diseases 464 WP4571 9 0.67 0.5 0.5 6.0595781921859e-07 0.020635406510022
88 WP4752 Base Excision Repair 503 WP4752 31 0.97 0.4 0.466666666666667 3.57124737003596e-13 0.0220340720140378
89 WP4720 Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway 491 WP4720 9 0.44 0.5 0.5 4.43345799464762e-09 0.0230432320025256
90 WP474 Endochondral Ossification 498 WP474 65 0.83 0.351851851851852 0.462962962962963 4.81536487673321e-20 0.0246820506324245
91 WP3875 ATR Signaling 281 WP3875 9 0.89 0.375 0.375 4.60260415203756e-08 0.0248929712443472
92 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM 314 WP3959 55 0.95 0.346153846153846 0.423076923076923 2.50026382158374e-16 0.0248929712443472
93 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 458 WP4560 18 0.94 0.411764705882353 0.470588235294118 6.52294438984146e-17 0.0254612754912739
94 WP2525 Trans-sulfuration and one carbon metabolism 128 WP2525 32 0.88 0.357142857142857 0.464285714285714 7.32732034249336e-10 0.0321645449138761
95 WP98 Prostaglandin Synthesis and Regulation 568 WP98 45 0.82 0.378378378378378 0.459459459459459 2.17394413943821e-22 0.0332806226599994
96 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS 397 WP4304 31 0.52 0.375 0.375 7.83386153710323e-26 0.0344632354643189
97 WP3599 Transcription factor regulation in adipogenesis 228 WP3599 22 0.86 0.368421052631579 0.368421052631579 1.55030261832076e-25 0.0362388400314306
98 WP1604 Codeine and Morphine Metabolism 42 WP1604 15 0.27 0.5 0.5 6.49286728094462e-06 0.0372370714105519
99 WP236 Adipogenesis 102 WP236 131 0.79 0.346153846153846 0.413461538461538 3.75341311013175e-54 0.0373548404617312
100 WP4661 Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension) 481 WP4661 6 0.33 0.5 0.5 0.0431468886224066 0.0431468886224066
101 WP3585 Cytosine methylation 222 WP3585 9 0.89 0.375 0.5 7.49087453817701e-07 0.046146524101977
102 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 279 WP3872 22 0.91 0.35 0.45 1.28737203377495e-08 0.0485074090657223
103 WP4399 MicroRNA network associated with chronic lymphocytic leukemia 416 WP4399 7 0.57 0.5 0.5 1.28737203377495e-08 0.0485074090657223
104 WP53 ID signaling pathway 523 WP53 16 0.81 0.307692307692308 0.384615384615385 1.33825325438479e-13 0.0542788662751285
105 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 564 WP734 19 0.84 0.3125 0.375 1.69191698398203e-15 0.0542788662751285
106 WP2881 Estrogen Receptor Pathway 182 WP2881 13 0.77 0.3 0.4 2.58938282317479e-38 0.0594386193019534
107 WP3963 Mevalonate pathway 315 WP3963 7 1 0.285714285714286 0.428571428571429 0.00314781622146767 0.0618737980244723
108 WP2197 Endothelin Pathways 81 WP2197 34 0.68 0.304347826086957 0.391304347826087 4.72920713559152e-27 0.0668243064530906
109 WP2355 Corticotropin-releasing hormone signaling pathway 100 WP2355 93 0.78 0.328767123287671 0.410958904109589 5.53853655041636e-45 0.0668243064530906
110 WP727 Monoamine Transport 561 WP727 32 0.53 0.294117647058824 0.529411764705882 4.62070637396041e-12 0.0730490654877152
111 WP167 Eicosanoid Synthesis 43 WP167 27 0.67 0.333333333333333 0.388888888888889 2.17394413943821e-22 0.0735098081465718
112 WP3624 Lung fibrosis 235 WP3624 63 0.67 0.30952380952381 0.428571428571429 1.55030261832076e-25 0.080115977530217
113 WP4584 Biomarkers for pyrimidine metabolism disorders 468 WP4584 15 0.8 0.333333333333333 0.5 2.56816439701713e-12 0.0832724893457054
114 WP4204 Tumor suppressor activity of SMARCB1 357 WP4204 33 0.79 0.269230769230769 0.423076923076923 7.79200875278231e-09 0.0908144088489654
115 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) 490 WP4719 30 0.7 0.333333333333333 0.380952380952381 2.17394413943821e-22 0.0918721376616465
116 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 230 WP3611 51 0.9 0.304347826086957 0.456521739130435 1.55030261832076e-25 0.093911573076689
117 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 64 WP2011 19 0.84 0.3125 0.4375 2.9447393377517e-11 0.103949453944605
118 WP3892 Development of pulmonary dendritic cells and macrophage subsets 288 WP3892 13 0.77 0.2 0.7 7.70437079680464e-06 0.111367348220358
119 WP2431 Spinal Cord Injury 114 WP2431 120 0.75 0.322222222222222 0.4 5.53853655041636e-45 0.114048118916392
120 WP272 Blood Clotting Cascade 148 WP272 23 0.52 0.333333333333333 0.5 1.05891161032475e-42 0.114803285411883
121 WP117 GPCRs, Other 5 WP117 94 0.23 0.318181818181818 0.363636363636364 3.77273931182897e-18 0.120172770046016
122 WP3596 miR-517 relationship with ARCN1 and USP1 227 WP3596 5 1 0.2 0.4 7.70437079680464e-06 0.123137649892892
123 WP3672 LncRNA-mediated mechanisms of therapeutic resistance 257 WP3672 12 0.58 0.285714285714286 0.428571428571429 1.61117377276123e-06 0.123137649892892
124 WP3995 Prion disease pathway 324 WP3995 37 0.84 0.258064516129032 0.419354838709677 1.42295577093001e-17 0.148008766451471
125 WP4147 PTF1A related regulatory pathway 342 WP4147 11 0.45 0.2 0.4 0.000808563677475246 0.156029921726251
126 WP2849 Hematopoietic Stem Cell Differentiation 163 WP2849 63 0.68 0.325581395348837 0.395348837209302 1.4645909158934e-29 0.156167098725433
127 WP3958 GPR40 Pathway 313 WP3958 16 0.81 0.307692307692308 0.538461538461538 1.06179313771239e-06 0.156624702837221
128 WP4249 Hedgehog Signaling Pathway 376 WP4249 44 0.77 0.264705882352941 0.411764705882353 6.45939424963396e-09 0.171056939850016
129 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 161 WP2846 3 0.33 0 1 0.191601747736878 0.191601747736878
130 WP3408 Evolocumab Mechanism 213 WP3408 3 0.33 0 1 0.191601747736878 0.191601747736878
131 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 80 WP2118 76 0.74 0.303571428571429 0.410714285714286 6.58880500842654e-23 0.19520059624092
132 WP3640 Imatinib and Chronic Myeloid Leukemia 243 WP3640 21 0.95 0.3 0.4 3.36912948711107e-08 0.202640916207215
133 WP2007 Iron metabolism in placenta 63 WP2007 12 0.67 0.25 0.375 0.000425327317103322 0.20667484530917
134 WP129 Matrix Metalloproteinases 8 WP129 30 0.73 0.272727272727273 0.409090909090909 1.66846236358396e-28 0.217106999492912
135 WP4754 IL-18 signaling pathway 505 WP4754 279 0.8 0.265765765765766 0.373873873873874 5.53853655041636e-45 0.224063872360977
136 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 207 WP3301 13 1 0.230769230769231 0.384615384615385 7.1834548445351e-10 0.236415904297976
137 WP704 Methylation Pathways 555 WP704 10 0.7 0.142857142857143 0.428571428571429 1.10795143781028e-12 0.241165469354808
138 WP3930 EDA Signalling in Hair Follicle Development 297 WP3930 14 0.64 0.222222222222222 0.555555555555556 6.78928901696758e-07 0.24293224118149
139 WP3967 miR-509-3p alteration of YAP1/ECM axis 317 WP3967 19 0.89 0.235294117647059 0.352941176470588 3.92971708713555e-06 0.246081089028509
140 WP2858 Ectoderm Differentiation 168 WP2858 144 0.78 0.285714285714286 0.366071428571429 6.10911950894992e-26 0.251410075884791
141 WP428 Wnt Signaling 384 WP428 118 0.79 0.301075268817204 0.365591397849462 5.00019440781505e-25 0.251410075884791
142 WP1434 Osteopontin Signaling 19 WP1434 13 1 0.230769230769231 0.461538461538462 1.51229007711679e-12 0.257536764433672
143 WP176 Folate Metabolism 46 WP176 73 0.6 0.295454545454545 0.409090909090909 1.55030261832076e-25 0.257536764433672
144 WP28 Selenium Metabolism and Selenoproteins 150 WP28 46 0.61 0.25 0.392857142857143 2.4987918295779e-23 0.257536764433672
145 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) 160 WP2840 88 0.64 0.267857142857143 0.375 1.4645909158934e-29 0.257536764433672
146 WP3617 Photodynamic therapy-induced NF-kB survival signaling 234 WP3617 35 0.86 0.233333333333333 0.4 1.55030261832076e-25 0.257536764433672
147 WP2059 Alzheimers Disease 75 WP2059 150 0.46 0.260869565217391 0.36231884057971 6.52294438984146e-17 0.264407820025205
148 WP4658 Small cell lung cancer 478 WP4658 98 0.91 0.269662921348315 0.359550561797753 1.33825325438479e-13 0.266714097046007
149 WP237 Glucocorticoid and Mineralcorticoid Metabolism 107 WP237 8 0.25 0 0.5 0.273007477872406 0.273007477872406
150 WP3287 Overview of nanoparticle effects 202 WP3287 19 0.79 0.266666666666667 0.4 1.55030261832076e-25 0.292450502904674
151 WP4586 Metabolism of alpha-linolenic acid 470 WP4586 7 0.86 0.166666666666667 0.5 0.0386740237126384 0.296626199889639
152 WP3580 Methionine De Novo and Salvage Pathway 220 WP3580 22 0.86 0.210526315789474 0.368421052631579 4.35964063989166e-11 0.301026666733762
153 WP4481 Resistin as a regulator of inflammation 422 WP4481 33 0.85 0.25 0.357142857142857 1.55030261832076e-25 0.310639518319511
154 WP3595 mir-124 predicted interactions with cell cycle and differentiation 226 WP3595 7 0.86 0.333333333333333 0.5 1.28871879017951e-06 0.311537001183337
155 WP4225 Pyrimidine metabolism and related diseases 369 WP4225 17 0.71 0.25 0.416666666666667 1.65319775729734e-07 0.312696646387934
156 WP24 Peptide GPCRs 111 WP24 75 0.28 0.285714285714286 0.428571428571429 1.91116166189054e-21 0.317365436064072
157 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma 405 WP4336 91 0.76 0.289855072463768 0.36231884057971 5.00019440781505e-25 0.320170838547363
158 WP4462 Platelet-mediated interactions with vascular and circulating cells 418 WP4462 17 0.88 0.266666666666667 0.4 1.28837373141904e-08 0.341095356415239
159 WP4493 Cells and Molecules involved in local acute inflammatory response 426 WP4493 17 0.76 0.307692307692308 0.384615384615385 1.55030261832076e-25 0.341095356415239
160 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 256 WP3670 21 0.81 0.176470588235294 0.352941176470588 2.45932835171728e-12 0.357129134137342
161 WP4538 Regulatory circuits of the STAT3 signaling pathway 447 WP4538 79 0.85 0.26865671641791 0.343283582089552 1.91116166189054e-21 0.363878327573958
162 WP229 Irinotecan Pathway 90 WP229 13 0.54 0.285714285714286 0.428571428571429 1.87627142351219e-05 0.372595026103777
163 WP4172 PI3K-Akt Signaling Pathway 350 WP4172 345 0.73 0.281746031746032 0.361111111111111 1.96319556679318e-26 0.389653492019368
164 WP3584 MECP2 and Associated Rett Syndrome 221 WP3584 71 0.72 0.274509803921569 0.352941176470588 2.08918249834541e-15 0.389709140526829
165 WP530 Cytokines and Inflammatory Response 524 WP530 27 0.52 0.214285714285714 0.357142857142857 1.55030261832076e-25 0.394616722859002
166 WP3888 VEGFA-VEGFR2 Signaling Pathway 286 WP3888 438 0.92 0.255583126550869 0.359801488833747 5.53853655041636e-45 0.415827475604265
167 WP4537 Hippo-Yap signaling pathway 446 WP4537 23 1 0.130434782608696 0.347826086956522 1.54778757247964e-06 0.425582638865984
168 WP4673 Genes involved in male infertility 483 WP4673 155 0.55 0.223529411764706 0.352941176470588 8.15687289296435e-21 0.434708802034794
169 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer 378 WP4258 104 0.73 0.276315789473684 0.342105263157895 5.00019440781505e-25 0.442641490692933
170 WP1528 Physiological and Pathological Hypertrophy of the Heart 26 WP1528 25 0.96 0.291666666666667 0.375 1.45750470372243e-17 0.443468145964458
171 WP1539 Angiogenesis 30 WP1539 24 1 0.25 0.375 2.08918249834541e-15 0.443468145964458
172 WP2586 Aryl Hydrocarbon Receptor Netpath 136 WP2586 48 0.83 0.225 0.35 1.44400359316927e-08 0.452666162731714
173 WP2865 IL1 and megakaryocytes in obesity 171 WP2865 25 0.84 0.238095238095238 0.380952380952381 5.19525794232389e-10 0.452666162731714
174 WP384 Apoptosis Modulation by HSP70 266 WP384 19 0.95 0.166666666666667 0.388888888888889 6.96540853859659e-18 0.452666162731714
175 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 556 WP706 164 0.61 0.31 0.35 7.75341732836066e-26 0.452666162731714
176 WP1742 TP53 Network 45 WP1742 20 0.9 0.222222222222222 0.388888888888889 1.28737203377495e-08 0.467750156194828
177 WP2507 Nanomaterial induced apoptosis 124 WP2507 20 0.95 0.105263157894737 0.368421052631579 1.28737203377495e-08 0.467750156194828
178 WP2267 Synaptic Vesicle Pathway 86 WP2267 52 0.6 0.258064516129032 0.354838709677419 6.97840140254166e-30 0.492132771972666
179 WP2038 Regulation of Microtubule Cytoskeleton 73 WP2038 49 0.86 0.285714285714286 0.357142857142857 5.70447887867626e-23 0.498108980109511
180 WP3594 Circadian rhythm related genes 225 WP3594 207 0.67 0.289855072463768 0.340579710144928 1.86144948015588e-42 0.502912219194388
181 WP186 Homologous recombination 51 WP186 13 0.92 0.333333333333333 0.333333333333333 3.57124737003596e-13 0.503680038828547
182 WP4299 Lamin A-processing pathway 392 WP4299 3 1 0.333333333333333 0.333333333333333 0.0375633720082355 0.525565992204199
183 WP26 Signal Transduction of S1P Receptor 139 WP26 26 0.92 0.208333333333333 0.333333333333333 1.36035451223937e-09 0.537154575485495
184 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway 299 WP3932 309 0.79 0.246913580246914 0.337448559670782 1.96319556679318e-26 0.55485006897197
185 WP3529 Zinc homeostasis 218 WP3529 37 0.65 0.208333333333333 0.333333333333333 1.09751947262418e-13 0.559735276252208
186 WP3613 Photodynamic therapy-induced unfolded protein response 232 WP3613 29 0.83 0.25 0.333333333333333 1.63572753987345e-09 0.592395677119481
187 WP455 GPCRs, Class A Rhodopsin-like 454 WP455 258 0.22 0.241379310344828 0.327586206896552 1.91116166189054e-21 0.594474156958518
188 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 198 WP314 44 0.91 0.175 0.325 1.28737203377495e-08 0.596740036001061
189 WP4321 Thermogenesis 401 WP4321 108 0.83 0.266666666666667 0.333333333333333 2.44977316588364e-24 0.602303776230422
190 WP1533 Vitamin B12 Metabolism 29 WP1533 53 0.57 0.2 0.333333333333333 1.55030261832076e-25 0.625924461178548
191 WP254 Apoptosis 132 WP254 86 0.93 0.225 0.3375 6.96540853859659e-18 0.630454225897172
192 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) 157 WP2817 33 0.76 0.32 0.32 8.1728342950092e-20 0.631033926043019
193 WP4286 Genotoxicity pathway 386 WP4286 63 0.78 0.244897959183673 0.326530612244898 6.52294438984146e-17 0.633739231633592
194 WP4228 Vitamin B6-dependent and responsive disorders 370 WP4228 5 0.8 0.25 0.25 0.00334024416831868 0.635216999029685
195 WP306 Focal Adhesion 195 WP306 202 0.86 0.248554913294798 0.323699421965318 1.96319556679318e-26 0.661870634611933
196 WP3941 Oxidative Damage 306 WP3941 41 0.9 0.243243243243243 0.324324324324324 1.28737203377495e-08 0.699923750757195
197 WP561 Heme Biosynthesis 533 WP561 9 0.89 0.25 0.25 6.5794345319789e-05 0.701076830955824
198 WP4541 Hippo-Merlin Signaling Dysregulation 450 WP4541 123 0.77 0.221052631578947 0.315789473684211 5.28168194977512e-22 0.723397294815617
199 WP2064 Neural Crest Differentiation 77 WP2064 102 0.63 0.25 0.328125 1.94200095136959e-19 0.727478052387628
200 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 260 WP3678 17 1 0.117647058823529 0.294117647058824 6.04285700943382e-06 0.727478052387628
201 WP3935 Leptin Insulin Overlap 302 WP3935 17 0.82 0.285714285714286 0.285714285714286 9.45573250233619e-09 0.741018446305419
202 WP1772 Apoptosis Modulation and Signaling 47 WP1772 93 0.85 0.189873417721519 0.316455696202532 6.96540853859659e-18 0.744856843612274
203 WP2877 Vitamin D Receptor Pathway 178 WP2877 186 0.63 0.271186440677966 0.322033898305085 7.99040804992212e-20 0.818823949216948
204 WP1591 Heart Development 37 WP1591 46 0.65 0.266666666666667 0.3 1.16900918682e-14 0.842767793418932
205 WP4357 NRF2-ARE regulation 410 WP4357 23 0.96 0.227272727272727 0.318181818181818 6.33815645362995e-08 0.87065004588454
206 WP2882 Nuclear Receptors Meta-Pathway 183 WP2882 322 0.69 0.238738738738739 0.315315315315315 2.58938282317479e-38 0.88225486075262
207 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 68 WP2032 68 0.91 0.274193548387097 0.32258064516129 8.47368187861688e-16 0.884931793800649
208 WP3998 Prader-Willi and Angelman Syndrome 326 WP3998 66 0.45 0.333333333333333 0.333333333333333 2.9765880724211e-12 0.892842095899067
209 WP2369 Histone Modifications 106 WP2369 70 0.43 0.166666666666667 0.3 4.29629046913145e-07 0.898693967045816
210 WP4540 Pathways Regulating Hippo Signaling 449 WP4540 99 0.81 0.225 0.325 1.45750470372243e-17 0.900720485325998
211 WP4022 Pyrimidine metabolism 331 WP4022 87 0.91 0.253164556962025 0.329113924050633 3.57124737003596e-13 0.90295173404126
212 WP4484 Control of immune tolerance by vasoactive intestinal peptide 425 WP4484 13 0.31 0 0.25 0.189083662421517 0.90837549057179
213 WP3527 Preimplantation Embryo 217 WP3527 60 0.52 0.193548387096774 0.290322580645161 1.4645909158934e-29 0.920619031124591
214 WP408 Oxidative Stress 335 WP408 34 0.85 0.206896551724138 0.310344827586207 2.4987918295779e-23 0.926181011736354
215 WP4297 Thiamine metabolic pathways 390 WP4297 9 0.89 0 0.25 0.171095325811961 0.927438681383965
216 WP1984 Integrated Breast Cancer Pathway 59 WP1984 155 0.92 0.27972027972028 0.314685314685315 3.61848623532521e-17 0.929014479457768
217 WP3972 PDGFR-beta pathway 320 WP3972 29 1 0.241379310344828 0.275862068965517 1.45750470372243e-17 0.936983896443534
218 WP15 Selenium Micronutrient Network 25 WP15 92 0.54 0.2 0.32 1.55030261832076e-25 0.94158668008034
219 WP1423 Ganglio Sphingolipid Metabolism 14 WP1423 13 0.62 0.25 0.25 4.87851969602103e-17 0.954898577153562
220 WP4298 Viral Acute Myocarditis 391 WP4298 85 0.82 0.228571428571429 0.314285714285714 1.55030261832076e-25 0.960973679911299
221 WP2374 Oncostatin M Signaling Pathway 109 WP2374 66 0.97 0.25 0.3125 1.45750470372243e-17 0.962619223865447
222 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 270 WP3850 31 0.94 0.241379310344828 0.310344827586207 2.9447393377517e-11 0.979681670178472
223 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 250 WP3657 22 0.86 0.315789473684211 0.315789473684211 1.28737203377495e-08 0.990973876560315
224 WP465 Tryptophan metabolism 474 WP465 42 0.64 0.259259259259259 0.333333333333333 1.2733947666864e-33 0.991085216247916
225 WP1541 Energy Metabolism 31 WP1541 48 0.88 0.30952380952381 0.333333333333333 4.7856489956754e-16 0.991457884585696
226 WP4148 Splicing factor NOVA regulated synaptic proteins 343 WP4148 42 0.74 0.258064516129032 0.32258064516129 8.59680057967434e-17 0.99308777325874
227 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 110 WP2380 144 0.85 0.227642276422764 0.284552845528455 2.46076597989882e-17 0.993357395961217
228 WP183 Proteasome Degradation 49 WP183 64 0.91 0.189655172413793 0.258620689655172 0.000102727400071607 0.993739319892961
229 WP3942 PPAR signaling pathway 307 WP3942 67 0.67 0.244444444444444 0.266666666666667 4.45382103461115e-22 0.993946338790036
230 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 407 WP4341 71 0.82 0.224137931034483 0.310344827586207 1.55030261832076e-25 0.997223465039722
231 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 71 WP2036 42 0.95 0.2 0.3 1.55030261832076e-25 0.998306181536745
232 WP262 EBV LMP1 signaling 140 WP262 24 0.83 0.2 0.3 1.31802719833037e-09 0.998306181536745
233 WP4008 NO/cGMP/PKG mediated Neuroprotection 328 WP4008 48 0.52 0.24 0.32 3.3920313877351e-19 0.998306181536745
234 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment 421 WP4480 9 0.89 0.125 0.25 1.55030261832076e-25 0.998306181536745
235 WP411 mRNA Processing 337 WP411 133 0.92 0.204918032786885 0.286885245901639 7.40715848733595e-20 0.999556795185293
236 WP4290 Metabolic reprogramming in colon cancer 388 WP4290 44 0.89 0.230769230769231 0.282051282051282 1.21134935033961e-14 0.999559974562214
237 WP2583 T-Cell Receptor and Co-stimulatory Signaling 135 WP2583 29 0.93 0.0740740740740741 0.185185185185185 0.0020390189701393 0.999564052655054
238 WP2113 Type III interferon signaling 79 WP2113 10 0.6 0.333333333333333 0.333333333333333 0.000341914298724229 0.999577405939352
239 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 83 WP2203 47 0.96 0.2 0.266666666666667 1.55030261832076e-25 0.999581638329153
240 WP3929 Chemokine signaling pathway 296 WP3929 165 0.75 0.233870967741935 0.306451612903226 1.11151548949677e-22 0.999581638329153
241 WP2878 PPAR Alpha Pathway 179 WP2878 26 0.62 0.3125 0.3125 2.35000378034819e-10 0.999593630002801
242 WP4211 Transcriptional cascade regulating adipogenesis 361 WP4211 13 1 0.307692307692308 0.307692307692308 3.05550468161626e-32 0.999597380647255
243 WP395 IL-4 Signaling Pathway 312 WP395 55 0.96 0.169811320754717 0.264150943396226 1.21006371795151e-15 0.999598637344068
244 WP4756 Renin Angiotensin Aldosterone System (RAAS) 506 WP4756 44 0.64 0.214285714285714 0.285714285714286 3.79036700534385e-25 0.999600844420397
245 WP2037 Prolactin Signaling Pathway 72 WP2037 76 0.96 0.164383561643836 0.246575342465753 1.21006371795151e-15 0.999622158178795
246 WP3646 Hepatitis C and Hepatocellular Carcinoma 246 WP3646 50 0.88 0.25 0.340909090909091 1.55030261832076e-25 0.999661972130556
247 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 215 WP3414 37 0.73 0.259259259259259 0.296296296296296 1.30274002920557e-12 0.999679395222021
248 WP1422 Sphingolipid pathway 13 WP1422 30 0.8 0.166666666666667 0.25 3.69949076638916e-07 0.999680873684117
249 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus 340 WP4142 20 0.75 0.2 0.2 1.78651764239784e-05 0.999680873684117
250 WP4725 Sphingolipid Metabolism (general overview) 496 WP4725 24 0.83 0.2 0.25 1.3073328528498e-06 0.999680873684117
251 WP2359 Parkin-Ubiquitin Proteasomal System pathway 101 WP2359 70 0.84 0.152542372881356 0.23728813559322 1.33825325438479e-13 0.999692096078023
252 WP2911 miRNA targets in ECM and membrane receptors 188 WP2911 43 0.51 0.227272727272727 0.272727272727273 1.96319556679318e-26 0.999694369321929
253 WP4262 Breast cancer pathway 380 WP4262 157 0.77 0.214876033057851 0.28099173553719 8.1728342950092e-20 0.999736194038243
254 WP2636 Common Pathways Underlying Drug Addiction 141 WP2636 42 0.57 0.166666666666667 0.25 8.80436312071741e-23 0.999745706039956
255 WP2828 Bladder Cancer 159 WP2828 41 0.93 0.184210526315789 0.289473684210526 2.88662493064661e-07 0.999745706039956
256 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 231 WP3612 24 0.88 0.0952380952380952 0.238095238095238 1.21006371795151e-15 0.999752419955776
257 WP4312 Rett syndrome causing genes 398 WP4312 49 0.76 0.216216216216216 0.297297297297297 1.22943627951508e-14 0.999766525303437
258 WP2533 Glycerophospholipid Biosynthetic Pathway 130 WP2533 30 0.83 0.08 0.16 3.98592395806362e-10 0.999787685558907
259 WP3940 One carbon metabolism and related pathways 305 WP3940 54 0.72 0.230769230769231 0.256410256410256 2.86780567028817e-25 0.999787685558907
260 WP4657 22q11.2 Deletion Syndrome 477 WP4657 92 0.63 0.258620689655172 0.310344827586207 5.10653311534479e-29 0.999801314777508
261 WP382 MAPK Signaling Pathway 264 WP382 249 0.78 0.261538461538462 0.302564102564103 5.53853655041636e-45 0.999829075430104
262 WP4666 Hepatitis B infection 482 WP4666 154 0.84 0.2 0.276923076923077 1.55030261832076e-25 0.999846173141814
263 WP107 Translation Factors 3 WP107 54 0.87 0.234042553191489 0.276595744680851 8.52450711689985e-13 0.999852323093054
264 WP1424 Globo Sphingolipid Metabolism 15 WP1424 21 0.95 0.2 0.2 4.87851969602103e-17 0.999852323093054
265 WP1584 Type II diabetes mellitus 35 WP1584 22 0.64 0.142857142857143 0.142857142857143 7.99040804992212e-20 0.999852323093054
266 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 65 WP2018 55 0.95 0.0961538461538462 0.192307692307692 1.21006371795151e-15 0.999852323093054
267 WP231 TNF alpha Signaling Pathway 94 WP231 94 0.94 0.204545454545455 0.284090909090909 1.55030261832076e-25 0.999852323093054
268 WP2371 Parkinsons Disease Pathway 108 WP2371 84 0.37 0.193548387096774 0.290322580645161 6.96540853859659e-18 0.999852323093054
269 WP244 Alpha 6 Beta 4 signaling pathway 116 WP244 35 0.94 0.121212121212121 0.181818181818182 2.61142544133486e-11 0.999852323093054
270 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 119 WP2453 16 0.94 0.0666666666666667 0.0666666666666667 1.10524321914212e-13 0.999852323093054
271 WP2456 HIF1A and PPARG regulation of glycolysis 120 WP2456 8 0.75 0.166666666666667 0.166666666666667 0.00320215171958638 0.999852323093054
272 WP2854 Gene regulatory network modelling somitogenesis 165 WP2854 11 0.55 0.166666666666667 0.166666666666667 0.0396104615656672 0.999852323093054
273 WP2870 Extracellular vesicle-mediated signaling in recipient cells 173 WP2870 30 0.9 0.185185185185185 0.222222222222222 1.47923810515956e-16 0.999852323093054
274 WP3 Phytochemical activity on NRF2 transcriptional activation 193 WP3 15 0.93 0.0714285714285714 0.214285714285714 0.00237947159212301 0.999852323093054
275 WP3286 Copper homeostasis 201 WP3286 54 0.87 0.234042553191489 0.297872340425532 3.71596808468601e-16 0.999852323093054
276 WP3298 Melatonin metabolism and effects 204 WP3298 42 0.62 0.269230769230769 0.307692307692308 1.86144948015588e-42 0.999852323093054
277 WP3413 NOTCH1 regulation of human endothelial cell calcification 214 WP3413 18 0.89 0.125 0.125 2.23804617426945e-12 0.999852323093054
278 WP3601 Composition of Lipid Particles 229 WP3601 10 0.4 0 0.25 0.191601747736878 0.999852323093054
279 WP3633 Caffeine and Theobromine metabolism 239 WP3633 4 0.25 0 0 0.999852323093054 0.999852323093054
280 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 253 WP3664 18 0.89 0.1875 0.3125 8.33920870140507e-09 0.999852323093054
281 WP3845 Canonical and Non-canonical Notch signaling 268 WP3845 27 0.81 0.0909090909090909 0.181818181818182 0.000608063456248664 0.999852323093054
282 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 274 WP3859 18 0.94 0.0588235294117647 0.0588235294117647 2.97846854097459e-06 0.999852323093054
283 WP3931 ESC Pluripotency Pathways 298 WP3931 119 0.7 0.265060240963855 0.289156626506024 1.04633266994318e-15 0.999852323093054
284 WP3945 TYROBP Causal Network 310 WP3945 63 0.9 0.12280701754386 0.175438596491228 1.51229007711679e-12 0.999852323093054
285 WP3965 Lipid Metabolism Pathway 316 WP3965 29 0.9 0.269230769230769 0.269230769230769 1.10524321914212e-13 0.999852323093054
286 WP3982 miRNA regulation of p53 pathway in prostate cancer 322 WP3982 34 0.68 0.0869565217391304 0.217391304347826 4.32292432502445e-07 0.999852323093054
287 WP4153 Degradation pathway of sphingolipids, including diseases 346 WP4153 10 0.8 0 0 0.999852323093054 0.999852323093054
288 WP4156 Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases 348 WP4156 2 1 0 0 0.999852323093054 0.999852323093054
289 WP4159 GABA receptor Signaling 349 WP4159 33 0.39 0.0769230769230769 0.0769230769230769 0.0013300266749614 0.999852323093054
290 WP4220 Neurotransmitter Disorders 365 WP4220 4 0.25 0 0 0.999852323093054 0.999852323093054
291 WP43 Oxidation by Cytochrome P450 393 WP43 63 0.48 0.133333333333333 0.166666666666667 7.53565262981462e-07 0.999852323093054
292 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome 400 WP4320 39 0.56 0.227272727272727 0.227272727272727 5.61788394294512e-16 0.999852323093054
293 WP4342 Vitamins A and D - action mechanisms 408 WP4342 3 1 0.333333333333333 0.333333333333333 1.20099662033474e-06 0.999852323093054
294 WP437 EGF/EGFR Signaling Pathway 411 WP437 164 0.95 0.206451612903226 0.232258064516129 1.4645909158934e-29 0.999852323093054
295 WP4482 Vitamin D in inflammatory diseases 423 WP4482 22 0.95 0.19047619047619 0.285714285714286 1.16949610776226e-27 0.999852323093054
296 WP4483 Relationship between inflammation, COX-2 and EGFR 424 WP4483 25 0.88 0.272727272727273 0.318181818181818 6.500496706318e-05 0.999852323093054
297 WP4519 Cerebral Organic Acidurias, including diseases 435 WP4519 7 1 0.285714285714286 0.285714285714286 1.97077141104003e-05 0.999852323093054
298 WP4522 Metabolic pathway of LDL, HDL and TG, including diseases 437 WP4522 17 0.53 0 0.222222222222222 0.0725218231021907 0.999852323093054
299 WP4535 Envelope proteins and their potential roles in EDMD physiopathology 444 WP4535 46 0.89 0.24390243902439 0.268292682926829 1.11151548949677e-22 0.999852323093054
300 WP4549 Fragile X Syndrome 453 WP4549 123 0.76 0.172043010752688 0.21505376344086 6.52294438984146e-17 0.999852323093054
301 WP4562 Canonical NF-KB pathway 460 WP4562 8 1 0 0.125 0.452666162731714 0.999852323093054
302 WP4585 Cancer immunotherapy by PD-1 blockade 469 WP4585 24 0.88 0.0952380952380952 0.19047619047619 2.79548473355309e-05 0.999852323093054
303 WP4724 Omega-9 FA synthesis 495 WP4724 16 0.75 0.166666666666667 0.25 9.83107916736652e-08 0.999852323093054
304 WP4758 Nephrotic syndrome 507 WP4758 45 0.73 0.151515151515152 0.181818181818182 7.19331431961561e-10 0.999852323093054
305 WP550 Biogenic Amine Synthesis 529 WP550 16 0.19 0.333333333333333 0.333333333333333 0.0013300266749614 0.999852323093054
306 WP100 Glutathione metabolism 1 WP100 23 0.7 0.0625 0.0625 2.4987918295779e-23 0.999852323093054
307 WP106 Alanine and aspartate metabolism 2 WP106 12 0.58 0.142857142857143 0.142857142857143 0.0013300266749614 0.999852323093054
308 WP111 Electron Transport Chain (OXPHOS system in mitochondria) 4 WP111 106 0.66 0.0714285714285714 0.128571428571429 1.43014316833318e-19 0.999852323093054
309 WP12 Osteoclast Signaling 6 WP12 16 0.75 0.166666666666667 0.25 1.51229007711679e-12 0.999852323093054
310 WP134 Pentose Phosphate Metabolism 9 WP134 7 1 0 0.142857142857143 0.154107526146787 0.999852323093054
311 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 12 WP1403 69 0.81 0.178571428571429 0.25 7.99040804992212e-20 0.999852323093054
312 WP143 Fatty Acid Beta Oxidation 17 WP143 34 0.79 0.111111111111111 0.111111111111111 6.0888051023505e-05 0.999852323093054
313 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway 18 WP1433 41 0.78 0.0625 0.125 4.08325260581342e-05 0.999852323093054
314 WP1449 Regulation of toll-like receptor signaling pathway 21 WP1449 145 0.77 0.117117117117117 0.198198198198198 1.55030261832076e-25 0.999852323093054
315 WP1471 Target Of Rapamycin (TOR) Signaling 23 WP1471 37 0.92 0.0882352941176471 0.117647058823529 8.28904921253337e-06 0.999852323093054
316 WP1531 Vitamin D Metabolism 28 WP1531 10 0.7 0.285714285714286 0.285714285714286 2.36116814219851e-05 0.999852323093054
317 WP1544 MicroRNAs in cardiomyocyte hypertrophy 32 WP1544 101 0.75 0.223684210526316 0.263157894736842 1.45750470372243e-17 0.999852323093054
318 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses 36 WP1589 9 0.89 0.125 0.25 2.91348117795513e-05 0.999852323093054
319 WP185 Integrin-mediated Cell Adhesion 50 WP185 104 0.84 0.195402298850575 0.218390804597701 5.28168194977512e-22 0.999852323093054
320 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 52 WP1941 4 1 0 0 0.999852323093054 0.999852323093054
321 WP195 IL-1 signaling pathway 54 WP195 57 0.96 0.127272727272727 0.181818181818182 1.5288509675647e-18 0.999852323093054
322 WP197 Cholesterol Biosynthesis Pathway 55 WP197 15 0.93 0.214285714285714 0.285714285714286 2.36116814219851e-05 0.999852323093054
323 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 58 WP1982 73 0.88 0.140625 0.171875 1.10524321914212e-13 0.999852323093054
324 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 70 WP2035 27 0.81 0.181818181818182 0.272727272727273 1.84528135455106e-08 0.999852323093054
325 WP205 IL-7 Signaling Pathway 74 WP205 25 1 0.16 0.2 0.000601597866207179 0.999852323093054
326 WP2112 IL17 signaling pathway 78 WP2112 32 0.84 0.148148148148148 0.222222222222222 1.31802719833037e-09 0.999852323093054
327 WP22 IL-9 Signaling Pathway 82 WP22 19 0.79 0.0666666666666667 0.0666666666666667 0.000601597866207179 0.999852323093054
328 WP2249 Metastatic brain tumor 84 WP2249 28 0.21 0.166666666666667 0.333333333333333 0.00291300857028192 0.999852323093054
329 WP2261 Signaling Pathways in Glioblastoma 85 WP2261 83 0.96 0.2375 0.25 1.45750470372243e-17 0.999852323093054
330 WP2272 Pathogenic Escherichia coli infection 87 WP2272 55 0.85 0.0851063829787234 0.191489361702128 4.18564642105688e-07 0.999852323093054
331 WP2289 Drug Induction of Bile Acid Pathway 89 WP2289 17 0.24 0.25 0.25 6.49286728094462e-06 0.999852323093054
332 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 92 WP2291 16 0.94 0.266666666666667 0.266666666666667 3.11005970071626e-15 0.999852323093054
333 WP2324 AGE/RAGE pathway 95 WP2324 66 0.95 0.142857142857143 0.206349206349206 1.45750470372243e-17 0.999852323093054
334 WP2333 Trans-sulfuration pathway 98 WP2333 10 1 0.2 0.2 7.49087453817701e-07 0.999852323093054
335 WP2436 Dopamine metabolism 115 WP2436 14 0.64 0.222222222222222 0.222222222222222 6.78665345557183e-11 0.999852323093054
336 WP2447 Amyotrophic lateral sclerosis (ALS) 118 WP2447 38 0.79 0.166666666666667 0.3 1.30274002920557e-12 0.999852323093054
337 WP2485 NAD Biosynthesis II (from tryptophan) 122 WP2485 8 0.75 0.166666666666667 0.166666666666667 1.2733947666864e-33 0.999852323093054
338 WP2509 Nanoparticle triggered autophagic cell death 125 WP2509 24 0.88 0.142857142857143 0.142857142857143 1.28737203377495e-08 0.999852323093054
339 WP2513 Nanoparticle triggered regulated necrosis 126 WP2513 12 0.92 0 0 0.795485118928105 0.999852323093054
340 WP2526 PDGF Pathway 129 WP2526 40 0.98 0.0769230769230769 0.128205128205128 1.21006371795151e-15 0.999852323093054
341 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 134 WP2572 74 0.78 0.275862068965517 0.310344827586207 4.81412003815079e-10 0.999852323093054
342 WP2637 Structural Pathway of Interleukin 1 (IL-1) 142 WP2637 50 0.98 0.142857142857143 0.204081632653061 1.21006371795151e-15 0.999852323093054
343 WP2643 Nanoparticle-mediated activation of receptor signaling 144 WP2643 29 0.97 0.178571428571429 0.214285714285714 0.00101315545629077 0.999852323093054
344 WP268 Notch Signaling 147 WP268 47 0.85 0.175 0.225 6.84417911248327e-08 0.999852323093054
345 WP2805 exRNA mechanism of action and biogenesis 151 WP2805 8 0.62 0.2 0.2 0.000217368536815086 0.999852323093054
346 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) 153 WP2813 18 0.61 0.272727272727273 0.272727272727273 1.1219536394885e-16 0.999852323093054
347 WP2853 Endoderm Differentiation 164 WP2853 146 0.77 0.223214285714286 0.258928571428571 5.00019440781505e-25 0.999852323093054
348 WP2857 Mesodermal Commitment Pathway 167 WP2857 157 0.74 0.206896551724138 0.258620689655172 5.00019440781505e-25 0.999852323093054
349 WP286 IL-3 Signaling Pathway 169 WP286 49 0.9 0.159090909090909 0.204545454545455 1.21006371795151e-15 0.999852323093054
350 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 170 WP2864 54 0.93 0.16 0.28 4.12289297028431e-17 0.999852323093054
351 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 172 WP2868 5 1 0 0 0.999852323093054 0.999852323093054
352 WP2873 Aryl Hydrocarbon Receptor Pathway 174 WP2873 48 0.65 0.129032258064516 0.225806451612903 4.12289297028431e-17 0.999852323093054
353 WP2875 Constitutive Androstane Receptor Pathway 176 WP2875 32 0.53 0.176470588235294 0.235294117647059 2.9447393377517e-11 0.999852323093054
354 WP2876 Pregnane X Receptor pathway 177 WP2876 33 0.55 0.166666666666667 0.222222222222222 2.9447393377517e-11 0.999852323093054
355 WP288 NLR Proteins 181 WP288 9 0.89 0.125 0.125 0.00237947159212301 0.999852323093054
356 WP2884 NRF2 pathway 184 WP2884 146 0.66 0.1875 0.260416666666667 2.4987918295779e-23 0.999852323093054
357 WP2889 Oxytocin signaling 185 WP2889 4 0.5 0 0 0.999852323093054 0.999852323093054
358 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 189 WP2916 17 0.94 0.1875 0.3125 6.05665966147348e-07 0.999852323093054
359 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 190 WP2942 9 0.67 0 0 0.990973876560315 0.999852323093054
360 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 192 WP299 35 0.46 0.25 0.25 1.20099662033474e-06 0.999852323093054
361 WP304 Kit receptor signaling pathway 194 WP304 60 0.98 0.169491525423729 0.220338983050847 1.45750470372243e-17 0.999852323093054
362 WP311 Synthesis and Degradation of Ketone Bodies 196 WP311 5 1 0.2 0.2 6.0888051023505e-05 0.999852323093054
363 WP313 Signaling of Hepatocyte Growth Factor Receptor 197 WP313 34 1 0.176470588235294 0.205882352941176 1.21006371795151e-15 0.999852323093054
364 WP325 Triacylglyceride Synthesis 200 WP325 26 0.54 0 0 0.999852323093054 0.999852323093054
365 WP3300 Dual hijack model of Vif in HIV infection 206 WP3300 9 0.67 0 0.166666666666667 0.118228105072828 0.999852323093054
366 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 208 WP3302 4 0.75 0.333333333333333 0.333333333333333 0.00071352422837791 0.999852323093054
367 WP3303 RAC1/PAK1/p38/MMP2 Pathway 209 WP3303 69 0.9 0.225806451612903 0.274193548387097 3.11796204582401e-18 0.999852323093054
368 WP357 Fatty Acid Biosynthesis 219 WP357 22 0.91 0.2 0.2 1.10524321914212e-13 0.999852323093054
369 WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma 224 WP3593 9 0.78 0 0 0.999852323093054 0.999852323093054
370 WP363 Wnt Signaling Pathway (Netpath) 237 WP363 53 0.91 0.208333333333333 0.208333333333333 1.45750470372243e-17 0.999852323093054
371 WP3630 NAD metabolism, sirtuins and aging 238 WP3630 11 0.91 0.2 0.3 2.25748011539398e-08 0.999852323093054
372 WP3634 Insulin signalling in human adipocytes (normal condition) 240 WP3634 8 1 0.125 0.125 7.99040804992212e-20 0.999852323093054
373 WP3635 Insulin signalling in human adipocytes (diabetic condition) 241 WP3635 8 1 0.125 0.125 7.99040804992212e-20 0.999852323093054
374 WP364 IL-6 signaling pathway 242 WP364 43 0.95 0.24390243902439 0.24390243902439 1.55030261832076e-25 0.999852323093054
375 WP3644 NAD+ metabolism 244 WP3644 16 0.88 0.142857142857143 0.285714285714286 2.25748011539398e-08 0.999852323093054
376 WP3645 NAD+ biosynthetic pathways 245 WP3645 22 0.77 0.176470588235294 0.294117647058824 2.25748011539398e-08 0.999852323093054
377 WP3651 Pathways Affected in Adenoid Cystic Carcinoma 247 WP3651 66 0.85 0.196428571428571 0.25 2.89465973850597e-12 0.999852323093054
378 WP3655 Hypothetical Craniofacial Development Pathway 248 WP3655 8 0.75 0.166666666666667 0.166666666666667 0.00407427421601939 0.999852323093054
379 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 249 WP3656 11 0.91 0.1 0.2 0.00279989180752429 0.999852323093054
380 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 251 WP3658 26 0.81 0.333333333333333 0.333333333333333 1.28160819617811e-23 0.999852323093054
381 WP366 TGF-beta Signaling Pathway 252 WP366 133 0.96 0.2109375 0.234375 1.4645909158934e-29 0.999852323093054
382 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 255 WP3668 25 0.92 0.217391304347826 0.304347826086957 1.91116166189054e-21 0.999852323093054
383 WP3674 Tgif disruption of Shh signaling 258 WP3674 9 0.44 0 0 0.999852323093054 0.999852323093054
384 WP3676 BDNF-TrkB Signaling 259 WP3676 34 0.88 0.166666666666667 0.2 1.84528135455106e-08 0.999852323093054
385 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 262 WP368 17 0.94 0.0625 0.0625 0.0167383786864681 0.999852323093054
386 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 263 WP3680 68 0.81 0.163636363636364 0.2 1.46702371634426e-15 0.999852323093054
387 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 267 WP3844 30 1 0.2 0.2 6.62772818839576e-10 0.999852323093054
388 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 269 WP3849 12 1 0.166666666666667 0.25 1.31802719833037e-09 0.999852323093054
389 WP3851 TLR4 Signaling and Tolerance 271 WP3851 30 0.83 0.08 0.16 1.55030261832076e-25 0.999852323093054
390 WP3853 ERK Pathway in Huntington's Disease 272 WP3853 15 0.87 0.230769230769231 0.307692307692308 1.84528135455106e-08 0.999852323093054
391 WP3858 Toll-like Receptor Signaling related to MyD88 273 WP3858 32 0.84 0 0.111111111111111 0.114048118916392 0.999852323093054
392 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 275 WP3863 62 0.81 0.14 0.22 1.21006371795151e-15 0.999852323093054
393 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway 276 WP3865 61 0.84 0.137254901960784 0.235294117647059 3.37870774082303e-13 0.999852323093054
394 WP3869 Cannabinoid receptor signaling 277 WP3869 29 0.79 0.0869565217391304 0.130434782608696 3.92161302035637e-08 0.999852323093054
395 WP3871 Valproic acid pathway 278 WP3871 13 0.62 0.125 0.125 0.0102047891408715 0.999852323093054
396 WP3874 Canonical and Non-Canonical TGF-B signaling 280 WP3874 17 1 0.0588235294117647 0.235294117647059 1.47923810515956e-16 0.999852323093054
397 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 283 WP3877 19 0.74 0 0.214285714285714 0.0594386193019534 0.999852323093054
398 WP3878 ATM Signaling Network in Development and Disease 284 WP3878 46 0.89 0.219512195121951 0.268292682926829 2.50026382158374e-16 0.999852323093054
399 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 285 WP3879 18 1 0.111111111111111 0.111111111111111 2.45237666239285e-07 0.999852323093054
400 WP391 Mitochondrial Gene Expression 290 WP391 20 0.8 0.125 0.1875 2.9447393377517e-11 0.999852323093054
401 WP3924 Hfe effect on hepcidin production 292 WP3924 7 0.57 0.25 0.25 0.00378182889135815 0.999852323093054
402 WP3925 Amino Acid metabolism 293 WP3925 91 0.73 0.166666666666667 0.227272727272727 2.58938282317479e-38 0.999852323093054
403 WP3927 BMP Signaling Pathway in Eyelid Development 295 WP3927 20 0.8 0.1875 0.25 1.1219536394885e-16 0.999852323093054
404 WP3933 Kennedy pathway from Sphingolipids 300 WP3933 15 0.8 0.0833333333333333 0.0833333333333333 0.000153115641692463 0.999852323093054
405 WP3934 Leptin and adiponectin 301 WP3934 10 0.8 0.125 0.125 1.13349503425421e-06 0.999852323093054
406 WP3937 Microglia Pathogen Phagocytosis Pathway 303 WP3937 40 0.9 0.0833333333333333 0.0833333333333333 1.57756315705304e-09 0.999852323093054
407 WP3938 miR-222 in Exercise-Induced Cardiac Growth 304 WP3938 4 1 0 0 0.999852323093054 0.999852323093054
408 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk 308 WP3943 6 1 0.333333333333333 0.333333333333333 1.76304737966141e-10 0.999852323093054
409 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity 318 WP3969 16 0.88 0.214285714285714 0.214285714285714 7.1806031181162e-15 0.999852323093054
410 WP3971 Role of Osx and miRNAs in tooth development 319 WP3971 36 0.28 0.2 0.2 1.74501293167954e-14 0.999852323093054
411 WP3981 miRNA regulation of prostate cancer signaling pathways 321 WP3981 59 0.54 0.15625 0.21875 1.28737203377495e-08 0.999852323093054
412 WP399 Wnt Signaling Pathway and Pluripotency 323 WP399 107 0.8 0.232558139534884 0.290697674418605 1.45750470372243e-17 0.999852323093054
413 WP400 p38 MAPK Signaling Pathway 327 WP400 34 0.97 0.181818181818182 0.242424242424242 4.7856489956754e-16 0.999852323093054
414 WP4018 Pathways in clear cell renal cell carcinoma 330 WP4018 87 0.91 0.164556962025316 0.189873417721519 1.10524321914212e-13 0.999852323093054
415 WP405 Eukaryotic Transcription Initiation 334 WP405 43 0.95 0.0975609756097561 0.146341463414634 2.41984712730741e-07 0.999852323093054
416 WP410 Exercise-induced Circadian Regulation 336 WP410 49 0.9 0.272727272727273 0.295454545454545 1.86144948015588e-42 0.999852323093054
417 WP4136 Fibrin Complement Receptor 3 Signaling Pathway 338 WP4136 42 0.71 0.0666666666666667 0.166666666666667 1.55030261832076e-25 0.999852323093054
418 WP4141 PI3K/AKT/mTOR - VitD3 Signalling 339 WP4141 22 0.86 0.263157894736842 0.263157894736842 3.87043570690072e-12 0.999852323093054
419 WP4146 Macrophage markers 341 WP4146 9 1 0 0.111111111111111 0.21102640351702 0.999852323093054
420 WP4150 Wnt Signaling in Kidney Disease 345 WP4150 39 0.69 0.222222222222222 0.222222222222222 8.33920870140507e-09 0.999852323093054
421 WP4155 Endometrial cancer 347 WP4155 63 0.94 0.152542372881356 0.220338983050847 1.04633266994318e-15 0.999852323093054
422 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging 352 WP4186 6 1 0.333333333333333 0.333333333333333 2.25748011539398e-08 0.999852323093054
423 WP4189 Mevalonate arm of cholesterol biosynthesis pathway with inhibitors 353 WP4189 2 1 0 0 0.999852323093054 0.999852323093054
424 WP4197 The human immune response to tuberculosis 356 WP4197 23 1 0.130434782608696 0.130434782608696 0.000341914298724229 0.999852323093054
425 WP4205 MET in type 1 papillary renal cell carcinoma 358 WP4205 59 0.88 0.115384615384615 0.173076923076923 3.90142119029615e-06 0.999852323093054
426 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway 359 WP4206 20 0.95 0.105263157894737 0.210526315789474 2.03101031117154e-10 0.999852323093054
427 WP4210 Tryptophan catabolism leading to NAD+ production 360 WP4210 16 0.69 0.0909090909090909 0.0909090909090909 1.2733947666864e-33 0.999852323093054
428 WP4217 Ebola Virus Pathway on Host 363 WP4217 132 0.89 0.135593220338983 0.186440677966102 7.15702783093164e-17 0.999852323093054
429 WP422 MAPK Cascade 364 WP422 33 1 0.212121212121212 0.272727272727273 1.06179313771239e-06 0.999852323093054
430 WP4223 Ras Signaling 367 WP4223 186 0.76 0.204225352112676 0.26056338028169 2.6982385516733e-21 0.999852323093054
431 WP4236 Disorders of the Krebs cycle 372 WP4236 7 1 0.142857142857143 0.142857142857143 0.000542153786249434 0.999852323093054
432 WP4239 Epithelial to mesenchymal transition in colorectal cancer 373 WP4239 164 0.78 0.1953125 0.2578125 5.10653311534479e-29 0.999852323093054
433 WP4241 Type 2 papillary renal cell carcinoma 375 WP4241 36 0.83 0.133333333333333 0.166666666666667 6.62772818839576e-10 0.999852323093054
434 WP4255 Non-small cell lung cancer 377 WP4255 72 0.93 0.149253731343284 0.238805970149254 1.45750470372243e-17 0.999852323093054
435 WP4263 Pancreatic adenocarcinoma pathway 381 WP4263 89 0.96 0.141176470588235 0.211764705882353 1.47923810515956e-16 0.999852323093054
436 WP4271 Vitamin B12 Disorders 383 WP4271 13 0.69 0 0.222222222222222 0.105553301023444 0.999852323093054
437 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders 389 WP4292 11 0.82 0.222222222222222 0.222222222222222 5.6500805039415e-14 0.999852323093054
438 WP430 Statin Pathway 394 WP430 33 0.45 0.133333333333333 0.266666666666667 0.00133659811986492 0.999852323093054
439 WP4313 Ferroptosis 399 WP4313 40 0.9 0.138888888888889 0.194444444444444 1.14291084616521e-05 0.999852323093054
440 WP4331 Neovascularisation processes 404 WP4331 37 1 0.189189189189189 0.27027027027027 3.37870774082303e-13 0.999852323093054
441 WP4352 Ciliary landscape 409 WP4352 220 0.9 0.137055837563452 0.208121827411168 4.19419091059679e-15 0.999852323093054
442 WP4389 Bile Acids synthesis and enterohepatic circulation 413 WP4389 13 0.38 0 0.2 0.191601747736878 0.999852323093054
443 WP4396 Nonalcoholic fatty liver disease 414 WP4396 160 0.84 0.133333333333333 0.207407407407407 1.55030261832076e-25 0.999852323093054
444 WP4397 Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors 415 WP4397 3 0.67 0 0 0.999852323093054 0.999852323093054
445 WP4478 LTF danger signal response pathway 419 WP4478 20 0.7 0.0714285714285714 0.214285714285714 1.55030261832076e-25 0.999852323093054
446 WP4479 Supression of HMGB1 mediated inflammation by THBD 420 WP4479 9 1 0 0.111111111111111 0.452666162731714 0.999852323093054
447 WP4494 Selective expression of chemokine receptors during T-cell polarization 427 WP4494 29 0.55 0.0625 0.125 0.00407427421601939 0.999852323093054
448 WP4496 Signal transduction through IL1R 429 WP4496 35 0.86 0.133333333333333 0.233333333333333 1.55030261832076e-25 0.999852323093054
449 WP4504 Cysteine and methionine catabolism 431 WP4504 15 0.87 0.153846153846154 0.153846153846154 5.6500805039415e-14 0.999852323093054
450 WP4506 Tyrosine Metabolism 432 WP4506 4 0.25 0 0 0.999852323093054 0.999852323093054
451 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases 434 WP4518 10 0.5 0.2 0.2 0.000377573164229441 0.999852323093054
452 WP4521 Glycosylation and related congenital defects 436 WP4521 25 1 0.12 0.16 1.02496252421453e-08 0.999852323093054
453 WP4523 Classical pathway of steroidogenesis, including diseases 438 WP4523 16 0.31 0 0.2 0.273007477872406 0.999852323093054
454 WP4524 The alternative pathway of fetal androgen synthesis 439 WP4524 12 0.33 0.25 0.25 2.8033361067803e-09 0.999852323093054
455 WP453 Inflammatory Response Pathway 440 WP453 33 0.67 0.0909090909090909 0.181818181818182 0.000442098767154395 0.999852323093054
456 WP4532 Intraflagellar transport proteins binding to dynein 441 WP4532 27 0.93 0.08 0.16 0.00558066527342552 0.999852323093054
457 WP4533 Transcription co-factors SKI and SKIL protein partners 442 WP4533 18 1 0.166666666666667 0.277777777777778 1.54778757247964e-06 0.999852323093054
458 WP4536 Genes related to primary cilium development (based on CRISPR) 445 WP4536 103 0.92 0.105263157894737 0.189473684210526 8.57900007846234e-13 0.999852323093054
459 WP4539 Synaptic signaling pathways associated with autism spectrum disorder 448 WP4539 51 0.76 0.256410256410256 0.256410256410256 9.26038985479124e-09 0.999852323093054
460 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions 451 WP4542 36 0.86 0.161290322580645 0.258064516129032 1.54778757247964e-06 0.999852323093054
461 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma 455 WP4553 38 0.29 0.181818181818182 0.272727272727273 3.04356671038824e-07 0.999852323093054
462 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment 457 WP4559 40 0.6 0.125 0.25 1.47923810515956e-16 0.999852323093054
463 WP4561 Cell migration and invasion through p75NTR 459 WP4561 31 0.9 0.214285714285714 0.285714285714286 3.88351886854851e-13 0.999852323093054
464 WP4564 Neural Crest Cell Migration during Development 461 WP4564 41 0.8 0.151515151515152 0.242424242424242 1.21006371795151e-15 0.999852323093054
465 WP4565 Neural Crest Cell Migration in Cancer 462 WP4565 44 0.82 0.166666666666667 0.25 1.21006371795151e-15 0.999852323093054
466 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway 465 WP4577 44 0.98 0.0930232558139535 0.116279069767442 0.000303680199088757 0.999852323093054
467 WP4595 Urea cycle and associated pathways 472 WP4595 21 0.76 0.25 0.3125 1.21134935033961e-14 0.999852323093054
468 WP4629 Computational Model of Aerobic Glycolysis 473 WP4629 12 0.92 0.181818181818182 0.181818181818182 1.94971495989183e-05 0.999852323093054
469 WP4655 Cytosolic DNA-sensing pathway 475 WP4655 76 0.72 0.109090909090909 0.145454545454545 1.55030261832076e-25 0.999852323093054
470 WP4659 Gastrin Signaling Pathway 479 WP4659 114 0.92 0.180952380952381 0.238095238095238 4.7856489956754e-16 0.999852323093054
471 WP4674 Head and Neck Squamous Cell Carcinoma 484 WP4674 70 0.94 0.121212121212121 0.166666666666667 1.47923810515956e-16 0.999852323093054
472 WP4685 Melanoma 485 WP4685 68 0.93 0.174603174603175 0.26984126984127 1.21006371795151e-15 0.999852323093054
473 WP47 Hedgehog Signaling Pathway Netpath 487 WP47 16 0.75 0.0833333333333333 0.25 0.0317273821116764 0.999852323093054
474 WP4705 Pathways of nucleic acid metabolism and innate immune sensing 488 WP4705 16 0.81 0.153846153846154 0.153846153846154 1.16208386478435e-12 0.999852323093054
475 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) 489 WP4718 47 0.87 0.219512195121951 0.268292682926829 1.16398114740138e-08 0.999852323093054
476 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) 492 WP4721 29 0.69 0.2 0.25 4.45382103461115e-22 0.999852323093054
477 WP4722 Glycerolipids and Glycerophospholipids 493 WP4722 24 0.75 0.0555555555555556 0.0555555555555556 0.000153115641692463 0.999852323093054
478 WP4723 Omega-3/Omega-6 FA synthesis 494 WP4723 15 0.73 0 0.0909090909090909 0.296626199889639 0.999852323093054
479 WP4726 Sphingolipid Metabolism (integrated pathway) 497 WP4726 25 0.84 0.19047619047619 0.238095238095238 1.3073328528498e-06 0.999852323093054
480 WP4742 Ketogenesis and Ketolysis 499 WP4742 8 1 0.125 0.125 6.0888051023505e-05 0.999852323093054
481 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism 500 WP4746 95 0.69 0.227272727272727 0.272727272727273 2.44977316588364e-24 0.999852323093054
482 WP4747 Netrin-UNC5B signaling Pathway 501 WP4747 52 0.85 0.181818181818182 0.272727272727273 2.5665992363522e-08 0.999852323093054
483 WP4751 HIPK2 in kidney fibrosis 502 WP4751 2 1 0 0 0.999852323093054 0.999852323093054
484 WP4753 Nucleotide Excision Repair 504 WP4753 44 0.98 0.255813953488372 0.27906976744186 3.57124737003596e-13 0.999852323093054
485 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation 509 WP4767 27 0.89 0.166666666666667 0.25 1.60955895014834e-18 0.999852323093054
486 WP477 Cytoplasmic Ribosomal Proteins 510 WP477 91 0.93 0.129411764705882 0.164705882352941 8.56966962716958e-10 0.999852323093054
487 WP4792 Purine metabolism 511 WP4792 13 0.85 0.272727272727273 0.272727272727273 3.92279863878209e-05 0.999852323093054
488 WP481 Insulin Signaling 512 WP481 161 0.93 0.186666666666667 0.246666666666667 2.30627807010563e-26 0.999852323093054
489 WP49 IL-2 Signaling Pathway 513 WP49 42 0.98 0.195121951219512 0.24390243902439 1.21006371795151e-15 0.999852323093054
490 WP496 Steroid Biosynthesis 514 WP496 10 0.4 0 0.25 0.386085732506969 0.999852323093054
491 WP500 Glycogen Synthesis and Degradation 516 WP500 40 0.9 0.138888888888889 0.194444444444444 9.51262628208688e-25 0.999852323093054
492 WP51 Regulation of Actin Cytoskeleton 518 WP51 151 0.77 0.213675213675214 0.273504273504274 1.04633266994318e-15 0.999852323093054
493 WP521 Amino acid conjugation of benzoic acid 520 WP521 5 0.2 0 0 0.999852323093054 0.999852323093054
494 WP524 G13 Signaling Pathway 521 WP524 41 0.85 0.2 0.2 6.63243812483213e-11 0.999852323093054
495 WP528 Acetylcholine Synthesis 522 WP528 7 0.57 0 0 0.999852323093054 0.999852323093054
496 WP534 Glycolysis and Gluconeogenesis 526 WP534 45 0.73 0.121212121212121 0.121212121212121 7.99040804992212e-20 0.999852323093054
497 WP560 TGF-beta Receptor Signaling 532 WP560 58 0.79 0.217391304347826 0.260869565217391 1.47923810515956e-16 0.999852323093054
498 WP581 EPO Receptor Signaling 535 WP581 26 0.96 0.08 0.08 0.000601597866207179 0.999852323093054
499 WP585 Interferon type I signaling pathways 536 WP585 55 0.95 0.173076923076923 0.230769230769231 9.45573250233619e-09 0.999852323093054
500 WP61 Notch Signaling Pathway Netpath 537 WP61 63 0.9 0.157894736842105 0.280701754385965 4.8712821556021e-23 0.999852323093054
501 WP615 Senescence and Autophagy in Cancer 538 WP615 108 0.86 0.193548387096774 0.258064516129032 1.55030261832076e-25 0.999852323093054
502 WP623 Oxidative phosphorylation 540 WP623 62 0.6 0 0.0540540540540541 0.0626324188453113 0.999852323093054
503 WP673 ErbB Signaling Pathway 542 WP673 91 0.89 0.209876543209877 0.259259259259259 3.46021469111041e-20 0.999852323093054
504 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 543 WP678 7 0.71 0.2 0.2 4.43345799464762e-09 0.999852323093054
505 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 544 WP688 5 0.6 0 0 0.999852323093054 0.999852323093054
506 WP690 Polyol Pathway 546 WP690 4 0.75 0 0 0.855645046418417 0.999852323093054
507 WP692 Sulfation Biotransformation Reaction 548 WP692 19 0.32 0 0 0.999852323093054 0.999852323093054
508 WP694 Arylamine metabolism 549 WP694 6 0.33 0 0 0.999852323093054 0.999852323093054
509 WP696 Benzo(a)pyrene metabolism 550 WP696 9 0.78 0 0.142857142857143 0.186101834726753 0.999852323093054
510 WP697 Estrogen metabolism 551 WP697 19 0.47 0 0 0.999852323093054 0.999852323093054
511 WP698 Glucuronidation 552 WP698 26 0.35 0.222222222222222 0.222222222222222 2.6913627863713e-23 0.999852323093054
512 WP699 Aflatoxin B1 metabolism 553 WP699 7 0.43 0 0 0.999852323093054 0.999852323093054
513 WP702 Metapathway biotransformation Phase I and II 554 WP702 188 0.48 0.133333333333333 0.188888888888889 2.4987918295779e-23 0.999852323093054
514 WP710 DNA Damage Response (only ATM dependent) 558 WP710 115 0.87 0.13 0.21 1.57756315705304e-09 0.999852323093054
515 WP712 Estrogen signaling pathway 559 WP712 23 0.91 0.19047619047619 0.333333333333333 1.21006371795151e-15 0.999852323093054
516 WP716 Vitamin A and Carotenoid Metabolism 560 WP716 44 0.5 0.181818181818182 0.272727272727273 9.28054409606823e-14 0.999852323093054
517 WP733 Serotonin Receptor 2 and STAT3 Signaling 563 WP733 4 0.75 0.333333333333333 0.333333333333333 0.0212542319346549 0.999852323093054
518 WP75 Toll-like Receptor Signaling Pathway 565 WP75 104 0.75 0.0897435897435897 0.179487179487179 1.55030261832076e-25 0.999852323093054
519 WP78 TCA Cycle (aka Krebs or citric acid cycle) 566 WP78 18 1 0 0.0555555555555556 0.345480440691871 0.999852323093054
520 WP80 Nucleotide GPCRs 567 WP80 11 0.73 0 0 0.999852323093054 0.999852323093054
521 WP127 IL-5 Signaling Pathway 7 WP127 40 0.95 0.236842105263158 0.263157894736842 1.21006371795151e-15 0.999852323093054
522 WP138 Androgen receptor signaling pathway 11 WP138 91 0.9 0.195121951219512 0.25609756097561 1.33825325438479e-13 0.999852323093054
523 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 16 WP1425 12 0.83 0.1 0.2 0.0044135122745415 0.999852323093054
524 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy 34 WP1559 12 0.58 0 0.142857142857143 0.452666162731714 0.999852323093054
525 WP1946 Cori Cycle 53 WP1946 17 0.82 0.142857142857143 0.142857142857143 7.99040804992212e-20 0.999852323093054
526 WP2034 Leptin signaling pathway 69 WP2034 76 0.99 0.213333333333333 0.266666666666667 6.63243812483213e-11 0.999852323093054
527 WP2290 RalA downstream regulated genes 91 WP2290 12 0.92 0.181818181818182 0.181818181818182 1.57756315705304e-09 0.999852323093054
528 WP23 B Cell Receptor Signaling Pathway 93 WP23 98 0.94 0.184782608695652 0.260869565217391 1.45750470372243e-17 0.999852323093054
529 WP2328 Allograft Rejection 96 WP2328 90 0.69 0.17741935483871 0.209677419354839 2.86780567028817e-25 0.999852323093054
530 WP2332 Interleukin-11 Signaling Pathway 97 WP2332 44 0.91 0.225 0.25 3.51846221320189e-12 0.999852323093054
531 WP2795 Cardiac Hypertrophic Response 149 WP2795 57 0.89 0.196078431372549 0.254901960784314 2.08918249834541e-15 0.999852323093054
532 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 233 WP3614 37 0.89 0.181818181818182 0.242424242424242 3.51846221320189e-12 0.999852323093054
533 WP3891 Benzene metabolism 287 WP3891 6 0.5 0 0 0.999852323093054 0.999852323093054
534 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 291 WP3915 132 0.89 0.136752136752137 0.170940170940171 7.99040804992212e-20 0.999852323093054
535 WP3926 ApoE and miR-146 in inflammation and atherosclerosis 294 WP3926 9 0.89 0 0.125 0.114048118916392 0.999852323093054
536 WP404 Nucleotide Metabolism 333 WP404 19 0.95 0.166666666666667 0.166666666666667 3.57124737003596e-13 0.999852323093054
537 WP4216 Chromosomal and microsatellite instability in colorectal cancer 362 WP4216 74 0.96 0.211267605633803 0.267605633802817 1.47923810515956e-16 0.999852323093054
538 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 382 WP4269 10 0.9 0.111111111111111 0.333333333333333 7.45368111307164e-07 0.999852323093054
539 WP4288 MTHFR deficiency 387 WP4288 27 0.7 0.315789473684211 0.315789473684211 1.69249742410717e-08 0.999852323093054
540 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells 396 WP4301 18 1 0.166666666666667 0.222222222222222 9.01134422889796e-05 0.999852323093054
541 WP4324 Mitochondrial complex I assembly model OXPHOS system 402 WP4324 56 0.8 0 0.0222222222222222 0.0626324188453113 0.999852323093054
542 WP4329 miRNAs involvement in the immune response in sepsis 403 WP4329 64 0.5 0.0625 0.1875 1.55030261832076e-25 0.999852323093054
543 WP438 Non-homologous end joining 412 WP438 11 0.91 0.1 0.1 0.00934439177317729 0.999852323093054
544 WP4495 IL-10 Anti-inflammatory Signaling Pathway 428 WP4495 12 0.92 0.181818181818182 0.272727272727273 1.55030261832076e-25 0.999852323093054
545 WP4507 Molybdenum cofactor (Moco) biosynthesis 433 WP4507 7 1 0.142857142857143 0.285714285714286 3.39506009152496e-24 0.999852323093054
546 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms 443 WP4534 48 0.92 0.159090909090909 0.272727272727273 8.80436312071741e-23 0.999852323093054
547 WP4558 Overview of interferons-mediated signaling pathway 456 WP4558 37 0.38 0.214285714285714 0.214285714285714 0.000341914298724229 0.999852323093054
548 WP4566 Translation inhibitors in chronically activated PDGFRA cells 463 WP4566 48 0.94 0.177777777777778 0.2 8.56966962716958e-10 0.999852323093054
549 WP4582 Cancer immunotherapy by CTLA4 blockade 466 WP4582 15 0.8 0 0 0.835939678356078 0.999852323093054
550 WP4656 Joubert Syndrome 476 WP4656 77 0.9 0.130434782608696 0.217391304347826 4.67701164770016e-10 0.999852323093054
551 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 517 WP501 16 0.31 0 0 0.999852323093054 0.999852323093054
552 WP619 Type II interferon signaling (IFNG) 539 WP619 37 0.84 0.193548387096774 0.258064516129032 9.44618578094348e-09 0.999852323093054
553 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 545 WP69 91 0.9 0.0975609756097561 0.182926829268293 1.55030261832076e-25 0.999852323093054
554 WP691 Tamoxifen metabolism 547 WP691 21 0.24 0.2 0.2 0.0372370714105519 0.999852323093054
555 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 562 WP732 20 0.75 0.2 0.266666666666667 6.52294438984146e-17 0.999852323093054
556 WP1981 Thyroxine (Thyroid Hormone) Production 57 WP1981 6 0 NA NA NA NA
557 WP2491 Diclofenac Metabolic Pathway 123 WP2491 4 0 NA NA NA NA
558 WP2536 Colchicine Metabolic Pathway 131 WP2536 1 0 NA NA NA NA
559 WP2596 Gastric acid production 137 WP2596 7 0 NA NA NA NA
560 WP2597 Secretion of Hydrochloric Acid in Parietal Cells 138 WP2597 5 0 NA NA NA NA
561 WP2640 Aripiprazole Metabolic Pathway 143 WP2640 2 0 NA NA NA NA
562 WP2646 Lidocaine metabolism 146 WP2646 2 0 NA NA NA NA
563 WP2816 Felbamate Metabolism 156 WP2816 2 0 NA NA NA NA
564 WP3627 Gut-Liver Indole Metabolism 236 WP3627 1 0 NA NA NA NA
565 WP3666 Metabolism of Dichloroethylene by CYP450 254 WP3666 1 0 NA NA NA NA
566 WP4174 Metabolism of Tetrahydrocannabinol (THC) 351 WP4174 2 0 NA NA NA NA
567 WP4194 Hormonal control of Pubertal Growth Spurt 355 WP4194 2 0 NA NA NA NA
568 WP4233 Acrylamide Biotransformation and Exposure Biomarkers 371 WP4233 1 0 NA NA NA NA
569 WP661 Glucose Homeostasis 541 WP661 1 0 NA NA NA NA

503
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@ -0,0 +1,503 @@
"set_id","name","GENE.SET","GLOB.STAT","NGLOB.STAT","PVAL"
"WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation","WP1991",39300,4370,0.001
"WP2023","Cell Differentiation - Index expanded","WP2023",43100,3920,0.001
"WP1602","Nicotine Activity on Dopaminergic Neurons","WP1602",40000,3630,0.002
"WP2029","Cell Differentiation - Index","WP2029",25100,4180,0.007
"WP3996","Ethanol effects on histone modifications","WP3996",86700,3100,0.008
"WP497","Urea cycle and metabolism of amino groups","WP497",52400,3280,0.008
"WP3944","Serotonin and anxiety-related events","WP3944",23400,3900,0.009
"WP2361","Gastric Cancer Network 1","WP2361",83100,3780,0.011
"WP4545","Oxysterols derived from cholesterol","WP4545",35000,3500,0.012
"WP2848","Differentiation Pathway","WP2848",80700,3110,0.013
"WP247","Small Ligand GPCRs","WP247",36000,3600,0.017
"WP4300","Extracellular vesicles in the crosstalk of cardiac cells","WP4300",55600,3270,0.017
"WP466","DNA Replication","WP466",152000,3720,0.019
"WP289","Myometrial Relaxation and Contraction Pathways","WP289",341000,2840,0.022
"WP236","Adipogenesis","WP236",292000,2810,0.026
"WP179","Cell Cycle","WP179",347000,3010,0.027
"WP2855","Dopaminergic Neurogenesis","WP2855",33200,3320,0.028
"WP3893","Development and heterogeneity of the ILC family","WP3893",56400,3130,0.029
"WP45","G1 to S cell cycle control","WP45",194000,3190,0.029
"WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma","WP4337",44300,3410,0.03
"WP4222","Phosphodiesterases in neuronal function","WP4222",93100,3000,0.031
"WP4760","PKC-gamma calcium signaling pathway in ataxia","WP4760",40100,3340,0.033
"WP35","G Protein Signaling Pathways","WP35",220000,2900,0.035
"WP3958","GPR40 Pathway","WP3958",40300,3100,0.035
"WP4149","White fat cell differentiation","WP4149",87000,2900,0.036
"WP474","Endochondral Ossification","WP474",154000,2850,0.041
"WP2355","Corticotropin-releasing hormone signaling pathway","WP2355",199000,2730,0.043
"WP2446","Retinoblastoma Gene in Cancer","WP2446",283000,3290,0.044
"WP2849","Hematopoietic Stem Cell Differentiation","WP2849",124000,2880,0.046
"WP4589","Major receptors targeted by epinephrine and norepinephrine","WP4589",36300,3300,0.046
"WP3591","Sleep regulation","WP3591",40000,3080,0.047
"WP4584","Biomarkers for pyrimidine metabolism disorders","WP4584",37600,3140,0.047
"WP1992","Genes targeted by miRNAs in adipocytes","WP1992",31600,3160,0.048
"WP2064","Neural Crest Differentiation","WP2064",178000,2770,0.048
"WP383","Striated Muscle Contraction Pathway","WP383",76100,3310,0.049
"WP241","One Carbon Metabolism","WP241",75100,3000,0.052
"WP2516","ATM Signaling Pathway","WP2516",109000,2950,0.052
"WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)","WP2815",32200,3220,0.052
"WP516","Hypertrophy Model","WP516",46500,3100,0.053
"WP58","Monoamine GPCRs","WP58",17300,3460,0.054
"WP4016","DNA IR-damage and cellular response via ATR","WP4016",223000,2970,0.055
"WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)","WP2840",156000,2790,0.058
"WP1601","Fluoropyrimidine Activity","WP1601",81100,2900,0.061
"WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways","WP706",265000,2650,0.061
"WP2406","Cardiac Progenitor Differentiation","WP2406",86600,2890,0.062
"WP554","ACE Inhibitor Pathway","WP554",36600,3320,0.064
"WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM","WP3959",147000,2820,0.065
"WP531","DNA Mismatch Repair","WP531",67300,3210,0.066
"WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition","WP4240",49900,3330,0.067
"WP2197","Endothelin Pathways","WP2197",66300,2880,0.069
"WP2525","Trans-sulfuration and one carbon metabolism","WP2525",80900,2890,0.069
"WP536","Calcium Regulation in the Cardiac Cell","WP536",302000,2820,0.069
"WP727","Monoamine Transport","WP727",49900,2930,0.07
"WP1530","miRNA Regulation of DNA Damage Response","WP1530",179000,2800,0.072
"WP3611","Photodynamic therapy-induced AP-1 survival signaling.","WP3611",128000,2790,0.075
"WP1423","Ganglio Sphingolipid Metabolism","WP1423",25100,3140,0.078
"WP707","DNA Damage Response","WP707",172000,2780,0.078
"WP3299","let-7 inhibition of ES cell reprogramming","WP3299",16900,3380,0.085
"WP1528","Physiological and Pathological Hypertrophy of the Heart","WP1528",68400,2850,0.086
"WP384","Apoptosis Modulation by HSP70","WP384",52400,2910,0.089
"WP2431","Spinal Cord Injury","WP2431",242000,2690,0.09
"WP3599","Transcription factor regulation in adipogenesis","WP3599",54200,2850,0.092
"WP3947","Serotonin and anxiety","WP3947",22000,3150,0.093
"WP558","Complement and Coagulation Cascades","WP558",114000,2910,0.099
"WP3995","Prion disease pathway","WP3995",84900,2740,0.1
"WP4752","Base Excision Repair","WP4752",85900,2860,0.105
"WP4204","Tumor suppressor activity of SMARCB1","WP4204",72400,2790,0.107
"WP4259","Disorders of Folate Metabolism and Transport","WP4259",33100,3010,0.108
"WP2806","Human Complement System","WP2806",177000,2820,0.111
"WP560","TGF-beta Receptor Signaling","WP560",123000,2680,0.113
"WP2276","Glial Cell Differentiation","WP2276",16100,3220,0.119
"WP3580","Methionine De Novo and Salvage Pathway","WP3580",52600,2770,0.119
"WP4698","Vitamin D-sensitive calcium signaling in depression","WP4698",60500,2750,0.125
"WP2113","Type III interferon signaling","WP2113",19400,3240,0.127
"WP136","Phase I biotransformations, non P450","WP136",15500,3110,0.13
"WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)","WP2814",34600,2880,0.13
"WP3679","Cell-type Dependent Selectivity of CCK2R Signaling","WP3679",27700,3070,0.133
"WP3892","Development of pulmonary dendritic cells and macrophage subsets","WP3892",31600,3160,0.134
"WP3287","Overview of nanoparticle effects","WP3287",41700,2780,0.136
"WP4225","Pyrimidine metabolism and related diseases","WP4225",35000,2910,0.136
"WP170","Nuclear Receptors","WP170",78400,2700,0.14
"WP2874","Liver X Receptor Pathway","WP2874",16100,3220,0.14
"WP4571","Urea cycle and related diseases","WP4571",17900,2980,0.142
"WP3640","Imatinib and Chronic Myeloid Leukemia","WP3640",55400,2770,0.149
"WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway","WP2032",162000,2610,0.15
"WP2363","Gastric Cancer Network 2","WP2363",81200,2800,0.151
"WP4022","Pyrimidine metabolism","WP4022",203000,2640,0.152
"WP2369","Histone Modifications","WP2369",81700,2720,0.155
"WP206","Fatty Acid Omega Oxidation","WP206",16400,3280,0.157
"WP2879","Farnesoid X Receptor Pathway","WP2879",21000,3000,0.16
"WP3875","ATR Signaling","WP3875",23700,2960,0.16
"WP2011","SREBF and miR33 in cholesterol and lipid homeostasis","WP2011",44700,2790,0.164
"WP2895","Differentiation of white and brown adipocyte ","WP2895",49400,2750,0.164
"WP3584","MECP2 and Associated Rett Syndrome","WP3584",133000,2600,0.164
"WP4658","Small cell lung cancer","WP4658",228000,2570,0.166
"WP1742","TP53 Network","WP1742",49900,2770,0.167
"WP2858","Ectoderm Differentiation","WP2858",285000,2570,0.167
"WP4224","Purine metabolism and related disorders","WP4224",51400,2710,0.168
"WP3613","Photodynamic therapy-induced unfolded protein response","WP3613",65000,2710,0.17
"WP2059","Alzheimers Disease","WP2059",179000,2590,0.179
"WP545","Complement Activation","WP545",44800,2990,0.18
"WP2267","Synaptic Vesicle Pathway","WP2267",81500,2630,0.181
"WP1971","Integrated Cancer Pathway","WP1971",115000,2670,0.183
"WP3624","Lung fibrosis","WP3624",112000,2660,0.185
"WP4754","IL-18 signaling pathway","WP4754",557000,2510,0.185
"WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation","WP3876",30300,2760,0.193
"WP4756","Renin Angiotensin Aldosterone System (RAAS)","WP4756",75400,2690,0.193
"WP2878","PPAR Alpha Pathway","WP2878",43300,2710,0.196
"WP1434","Osteopontin Signaling","WP1434",36500,2810,0.197
"WP698","Glucuronidation","WP698",25100,2790,0.197
"WP176","Folate Metabolism","WP176",116000,2630,0.198
"WP465","Tryptophan metabolism","WP465",71700,2660,0.2
"WP186","Homologous recombination","WP186",33400,2780,0.201
"WP3594","Circadian rhythm related genes","WP3594",349000,2530,0.202
"WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement","WP4560",47500,2790,0.208
"WP4312","Rett syndrome causing genes","WP4312",96900,2620,0.215
"WP3656","Interleukin-1 Induced Activation of NF-kappa-B","WP3656",27400,2740,0.217
"WP4288","MTHFR deficiency","WP4288",51800,2720,0.219
"WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)","WP4719",56000,2670,0.222
"WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS","WP4304",43800,2740,0.223
"WP3529","Zinc homeostasis","WP3529",63800,2660,0.224
"WP2338","miRNA Biogenesis","WP2338",17000,2840,0.225
"WP3585","Cytosine methylation","WP3585",21900,2730,0.225
"WP4495","IL-10 Anti-inflammatory Signaling Pathway ","WP4495",30000,2720,0.225
"WP2007","Iron metabolism in placenta","WP2007",22200,2770,0.227
"WP4249","Hedgehog Signaling Pathway","WP4249",88300,2600,0.227
"WP98","Prostaglandin Synthesis and Regulation","WP98",97200,2630,0.227
"WP2865","IL1 and megakaryocytes in obesity","WP2865",56300,2680,0.229
"WP1422","Sphingolipid pathway","WP1422",62800,2620,0.233
"WP4290","Metabolic reprogramming in colon cancer","WP4290",102000,2620,0.234
"WP4493","Cells and Molecules involved in local acute inflammatory response ","WP4493",36600,2810,0.236
"WP117","GPCRs, Other","WP117",58000,2640,0.24
"WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway","WP3670",44800,2640,0.243
"WP24","Peptide GPCRs","WP24",56100,2670,0.246
"WP1545","miRNAs involved in DNA damage response","WP1545",37500,2680,0.248
"WP3930","EDA Signalling in Hair Follicle Development","WP3930",24800,2760,0.248
"WP138","Androgen receptor signaling pathway","WP138",207000,2530,0.25
"WP34","Ovarian Infertility Genes","WP34",44700,2630,0.25
"WP4629","Computational Model of Aerobic Glycolysis","WP4629",31700,2880,0.25
"WP4286","Genotoxicity pathway","WP4286",125000,2560,0.255
"WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex","WP3657",50700,2670,0.256
"WP2038","Regulation of Microtubule Cytoskeleton","WP2038",108000,2570,0.27
"WP2507","Nanomaterial induced apoptosis","WP2507",49700,2610,0.272
"WP3963","Mevalonate pathway","WP3963",19700,2810,0.272
"WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway","WP3877",36900,2640,0.273
"WP4357","NRF2-ARE regulation","WP4357",56900,2590,0.273
"WP530","Cytokines and Inflammatory Response","WP530",37100,2650,0.277
"WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)","WP2817",64100,2570,0.278
"WP1589","Folate-Alcohol and Cancer Pathway Hypotheses","WP1589",21700,2710,0.285
"WP430","Statin Pathway","WP430",39400,2620,0.285
"WP4673","Genes involved in male infertility","WP4673",212000,2490,0.286
"WP4535","Envelope proteins and their potential roles in EDMD physiopathology","WP4535",102000,2540,0.288
"WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma","WP4553",29300,2660,0.289
"WP3941","Oxidative Damage","WP3941",94800,2560,0.29
"WP4481","Resistin as a regulator of inflammation","WP4481",72200,2580,0.29
"WP3942","PPAR signaling pathway","WP3942",113000,2500,0.293
"WP428","Wnt Signaling","WP428",233000,2500,0.294
"WP4172","PI3K-Akt Signaling Pathway","WP4172",622000,2470,0.296
"WP1772","Apoptosis Modulation and Signaling","WP1772",197000,2500,0.298
"WP1531","Vitamin D Metabolism","WP1531",18900,2700,0.301
"WP1984","Integrated Breast Cancer Pathway","WP1984",355000,2490,0.301
"WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation","WP314",102000,2540,0.301
"WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3","WP4341",146000,2520,0.302
"WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases","WP4518",13600,2720,0.304
"WP1591","Heart Development","WP1591",75600,2520,0.316
"WP3407","FTO Obesity Variant Mechanism","WP3407",18900,2700,0.319
"WP129","Matrix Metalloproteinases","WP129",57000,2590,0.325
"WP1455","Serotonin Transporter Activity","WP1455",21000,2630,0.325
"WP4462","Platelet-mediated interactions with vascular and circulating cells","WP4462",39600,2640,0.329
"WP4298","Viral Acute Myocarditis","WP4298",174000,2480,0.333
"WP254","Apoptosis","WP254",198000,2480,0.335
"WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy","WP2118",142000,2540,0.336
"WP3655","Hypothetical Craniofacial Development Pathway","WP3655",16200,2700,0.336
"WP107","Translation Factors","WP107",118000,2520,0.337
"WP167","Eicosanoid Synthesis","WP167",45600,2530,0.34
"WP3871","Valproic acid pathway","WP3871",21100,2640,0.341
"WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging","WP4186",15800,2630,0.341
"WP3972","PDGFR-beta pathway","WP3972",73500,2540,0.347
"WP4558","Overview of interferons-mediated signaling pathway","WP4558",36000,2570,0.347
"WP2853","Endoderm Differentiation","WP2853",275000,2450,0.348
"WP3630","NAD metabolism, sirtuins and aging","WP3630",26000,2600,0.349
"WP3878","ATM Signaling Network in Development and Disease ","WP3878",103000,2510,0.35
"WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein","WP3872",50400,2520,0.352
"WP3888","VEGFA-VEGFR2 Signaling Pathway","WP3888",986000,2450,0.358
"WP4583","Biomarkers for urea cycle disorders","WP4583",21000,2620,0.358
"WP197","Cholesterol Biosynthesis Pathway","WP197",35700,2550,0.36
"WP26","Signal Transduction of S1P Receptor","WP26",60900,2540,0.361
"WP4148","Splicing factor NOVA regulated synaptic proteins","WP4148",77400,2500,0.364
"WP585","Interferon type I signaling pathways","WP585",129000,2480,0.364
"WP306","Focal Adhesion","WP306",426000,2460,0.366
"WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome","WP4320",55400,2520,0.367
"WP734","Serotonin Receptor 4/6/7 and NR3C Signaling","WP734",40800,2550,0.368
"WP4321","Thermogenesis","WP4321",223000,2470,0.369
"WP3595","mir-124 predicted interactions with cell cycle and differentiation ","WP3595",15800,2630,0.371
"WP4538","Regulatory circuits of the STAT3 signaling pathway","WP4538",166000,2480,0.371
"WP1541","Energy Metabolism","WP1541",105000,2500,0.378
"WP2371","Parkinsons Disease Pathway","WP2371",77000,2480,0.378
"WP4211","Transcriptional cascade regulating adipogenesis","WP4211",32800,2530,0.38
"WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR","WP3414",67700,2510,0.381
"WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)","WP4718",102000,2490,0.382
"WP4725","Sphingolipid Metabolism (general overview)","WP4725",49800,2490,0.382
"WP272","Blood Clotting Cascade","WP272",30500,2540,0.383
"WP3998","Prader-Willi and Angelman Syndrome","WP3998",74300,2480,0.383
"WP2359","Parkin-Ubiquitin Proteasomal System pathway","WP2359",145000,2460,0.385
"WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer","WP2864",123000,2460,0.386
"WP411","mRNA Processing","WP411",3e+05,2460,0.386
"WP4147","PTF1A related regulatory pathway","WP4147",12900,2580,0.387
"WP3527","Preimplantation Embryo","WP3527",77300,2490,0.392
"WP322","Osteoblast Signaling","WP322",18300,2610,0.393
"WP4482","Vitamin D in inflammatory diseases","WP4482",52400,2500,0.398
"WP4753","Nucleotide Excision Repair","WP4753",106000,2460,0.399
"WP561","Heme Biosynthesis","WP561",20000,2500,0.4
"WP4236","Disorders of the Krebs cycle","WP4236",17500,2500,0.406
"WP3971","Role of Osx and miRNAs in tooth development","WP3971",24700,2470,0.408
"WP4523","Classical pathway of steroidogenesis, including diseases","WP4523",12800,2550,0.409
"WP410","Exercise-induced Circadian Regulation","WP410",109000,2480,0.41
"WP4533","Transcription co-factors SKI and SKIL protein partners","WP4533",45100,2510,0.411
"WP53","ID signaling pathway","WP53",32400,2490,0.417
"WP3644","NAD+ metabolism","WP3644",34700,2480,0.422
"WP3926","ApoE and miR-146 in inflammation and atherosclerosis","WP3926",20000,2500,0.422
"WP1946","Cori Cycle","WP1946",34900,2490,0.425
"WP262","EBV LMP1 signaling","WP262",49200,2460,0.426
"WP500","Glycogen Synthesis and Degradation","WP500",88500,2460,0.426
"WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness","WP3301",32500,2500,0.427
"WP3617","Photodynamic therapy-induced NF-kB survival signaling","WP3617",72700,2420,0.428
"WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling","WP3850",71500,2470,0.428
"WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment","WP4480",20100,2520,0.428
"WP15","Selenium Micronutrient Network","WP15",121000,2430,0.431
"WP3596","miR-517 relationship with ARCN1 and USP1","WP3596",12500,2500,0.434
"WP183","Proteasome Degradation","WP183",141000,2440,0.436
"WP2881","Estrogen Receptor Pathway","WP2881",24600,2460,0.439
"WP2875","Constitutive Androstane Receptor Pathway","WP2875",41400,2440,0.443
"WP4008","NO/cGMP/PKG mediated Neuroprotection","WP4008",61700,2470,0.444
"WP4539","Synaptic signaling pathways associated with autism spectrum disorder","WP4539",95600,2450,0.445
"WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma","WP4336",167000,2420,0.447
"WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer","WP2291",36300,2420,0.451
"WP455","GPCRs, Class A Rhodopsin-like","WP455",141000,2430,0.454
"WP2485","NAD Biosynthesis II (from tryptophan)","WP2485",14800,2470,0.455
"WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation","WP4767",58400,2430,0.461
"WP4521","Glycosylation and related congenital defects","WP4521",60500,2420,0.479
"WP3672","LncRNA-mediated mechanisms of therapeutic resistance","WP3672",17100,2440,0.48
"WP2586","Aryl Hydrocarbon Receptor Netpath","WP2586",96900,2420,0.482
"WP2583","T-Cell Receptor and Co-stimulatory Signaling","WP2583",65000,2410,0.49
"WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1","WP4269",21700,2410,0.499
"WP4726","Sphingolipid Metabolism (integrated pathway)","WP4726",50000,2380,0.507
"WP678","Arachidonate Epoxygenase / Epoxide Hydrolase","WP678",11900,2380,0.512
"WP3298","Melatonin metabolism and effects","WP3298",62600,2410,0.515
"WP1533","Vitamin B12 Metabolism","WP1533",71500,2380,0.516
"WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia","WP3658",50100,2390,0.516
"WP3927","BMP Signaling Pathway in Eyelid Development","WP3927",38100,2380,0.516
"WP3935","Leptin Insulin Overlap","WP3935",33600,2400,0.516
"WP2332","Interleukin-11 Signaling Pathway","WP2332",96300,2410,0.517
"WP524","G13 Signaling Pathway","WP524",83800,2390,0.517
"WP4331","Neovascularisation processes","WP4331",89100,2410,0.519
"WP4657","22q11.2 Deletion Syndrome","WP4657",140000,2410,0.52
"WP2911","miRNA targets in ECM and membrane receptors","WP2911",51000,2320,0.521
"WP1403","AMP-activated Protein Kinase (AMPK) Signaling","WP1403",135000,2400,0.526
"WP2112","IL17 signaling pathway","WP2112",65000,2410,0.526
"WP28","Selenium Metabolism and Selenoproteins","WP28",66800,2380,0.528
"WP408","Oxidative Stress","WP408",68400,2360,0.528
"WP4540","Pathways Regulating Hippo Signaling","WP4540",190000,2400,0.535
"WP268","Notch Signaling","WP268",95800,2390,0.536
"WP2857","Mesodermal Commitment Pathway","WP2857",278000,2400,0.536
"WP4724","Omega-9 FA synthesis","WP4724",28000,2330,0.545
"WP229","Irinotecan Pathway","WP229",16300,2330,0.55
"WP3929","Chemokine signaling pathway","WP3929",296000,2390,0.551
"WP4507","Molybdenum cofactor (Moco) biosynthesis","WP4507",13900,2320,0.553
"WP3646","Hepatitis C and Hepatocellular Carcinoma","WP3646",104000,2370,0.558
"WP501","GPCRs, Class C Metabotropic glutamate, pheromone","WP501",11600,2320,0.564
"WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation","WP1425",23000,2300,0.57
"WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway","WP2203",107000,2370,0.572
"WP3","Phytochemical activity on NRF2 transcriptional activation","WP3",32700,2340,0.572
"WP80","Nucleotide GPCRs","WP80",18600,2320,0.572
"WP311","Synthesis and Degradation of Ketone Bodies","WP311",11400,2280,0.573
"WP4586","Metabolism of alpha-linolenic acid","WP4586",13700,2280,0.575
"WP2636","Common Pathways Underlying Drug Addiction","WP2636",56100,2340,0.576
"WP2876","Pregnane X Receptor pathway","WP2876",41800,2320,0.576
"WP4742","Ketogenesis and Ketolysis","WP4742",18400,2300,0.577
"WP3851","TLR4 Signaling and Tolerance","WP3851",58900,2360,0.584
"WP2916","Interactome of polycomb repressive complex 2 (PRC2) ","WP2916",37400,2330,0.586
"WP4191","Caloric restriction and aging","WP4191",18500,2310,0.587
"WP134","Pentose Phosphate Metabolism","WP134",15400,2200,0.589
"WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway","WP3932",581000,2390,0.589
"WP395","IL-4 Signaling Pathway","WP395",125000,2360,0.592
"WP2272","Pathogenic Escherichia coli infection","WP2272",110000,2330,0.594
"WP704","Methylation Pathways","WP704",16100,2300,0.595
"WP399","Wnt Signaling Pathway and Pluripotency","WP399",204000,2370,0.596
"WP4541","Hippo-Merlin Signaling Dysregulation","WP4541",222000,2360,0.597
"WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma","WP3593",15700,2250,0.599
"WP47","Hedgehog Signaling Pathway Netpath","WP47",27800,2320,0.599
"WP61","Notch Signaling Pathway Netpath","WP61",134000,2350,0.599
"WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway","WP2036",94000,2350,0.605
"WP3967","miR-509-3p alteration of YAP1/ECM axis","WP3967",38200,2240,0.608
"WP2249","Metastatic brain tumor","WP2249",13300,2220,0.61
"WP4141","PI3K/AKT/mTOR - VitD3 Signalling","WP4141",44100,2320,0.611
"WP4537","Hippo-Yap signaling pathway","WP4537",50700,2300,0.613
"WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer","WP4258",179000,2360,0.614
"WP2436","Dopamine metabolism","WP2436",20400,2260,0.616
"WP3940","One carbon metabolism and related pathways","WP3940",91100,2340,0.617
"WP51","Regulation of Actin Cytoskeleton","WP51",275000,2350,0.62
"WP4595","Urea cycle and associated pathways","WP4595",37100,2320,0.625
"WP4271","Vitamin B12 Disorders","WP4271",20500,2280,0.627
"WP2854","Gene regulatory network modelling somitogenesis ","WP2854",13200,2200,0.628
"WP2456","HIF1A and PPARG regulation of glycolysis","WP2456",13100,2180,0.63
"WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ","WP3849",27000,2250,0.631
"WP404","Nucleotide Metabolism","WP404",40400,2250,0.632
"WP3933","Kennedy pathway from Sphingolipids","WP3933",27500,2290,0.639
"WP477","Cytoplasmic Ribosomal Proteins","WP477",167000,1960,0.64
"WP3300","Dual hijack model of Vif in HIV infection","WP3300",13000,2160,0.644
"WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway","WP2380",290000,2360,0.65
"WP1544","MicroRNAs in cardiomyocyte hypertrophy","WP1544",179000,2350,0.653
"WP2533","Glycerophospholipid Biosynthetic Pathway","WP2533",56900,2270,0.653
"WP3943","Robo4 and VEGF Signaling Pathways Crosstalk","WP3943",13100,2190,0.653
"WP4496","Signal transduction through IL1R","WP4496",68800,2290,0.653
"WP712","Estrogen signaling pathway","WP712",47900,2280,0.656
"WP4566","Translation inhibitors in chronically activated PDGFRA cells","WP4566",104000,2320,0.657
"WP4562","Canonical NF-KB pathway","WP4562",17500,2190,0.667
"WP4389","Bile Acids synthesis and enterohepatic circulation ","WP4389",10600,2110,0.668
"WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds","WP3664",35900,2250,0.669
"WP4297","Thiamine metabolic pathways","WP4297",17600,2200,0.67
"WP619","Type II interferon signaling (IFNG)","WP619",67600,2180,0.672
"WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease","WP3668",52000,2260,0.677
"WP391","Mitochondrial Gene Expression","WP391",35700,2230,0.678
"WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms","WP4534",97900,2280,0.678
"WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling","WP3612",46100,2200,0.679
"WP1424","Globo Sphingolipid Metabolism","WP1424",44700,2230,0.68
"WP4559","Interactions between immune cells and microRNAs in tumor microenvironment","WP4559",53000,2210,0.681
"WP2795","Cardiac Hypertrophic Response","WP2795",119000,2330,0.683
"WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer","WP2868",10200,2040,0.684
"WP127","IL-5 Signaling Pathway","WP127",87500,2300,0.687
"WP3925","Amino Acid metabolism","WP3925",151000,2290,0.688
"WP231","TNF alpha Signaling Pathway","WP231",204000,2320,0.69
"WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway","WP3865",117000,2300,0.694
"WP4522","Metabolic pathway of LDL, HDL and TG, including diseases","WP4522",19300,2150,0.696
"WP2882","Nuclear Receptors Meta-Pathway","WP2882",516000,2330,0.698
"WP4666","Hepatitis B infection","WP4666",305000,2340,0.699
"WP78","TCA Cycle (aka Krebs or citric acid cycle)","WP78",38300,2130,0.701
"WP4792","Purine metabolism","WP4792",23800,2160,0.706
"WP4216","Chromosomal and microsatellite instability in colorectal cancer ","WP4216",165000,2320,0.709
"WP2374","Oncostatin M Signaling Pathway","WP2374",147000,2300,0.71
"WP4142","Metabolism of Spingolipids in ER and Golgi apparatus","WP4142",32300,2150,0.714
"WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection","WP3863",112000,2240,0.715
"WP2328","Allograft Rejection","WP2328",131000,2120,0.721
"WP3845","Canonical and Non-canonical Notch signaling","WP3845",49200,2240,0.721
"WP2884","NRF2 pathway","WP2884",218000,2270,0.722
"WP4519","Cerebral Organic Acidurias, including diseases","WP4519",14500,2080,0.723
"WP2037","Prolactin Signaling Pathway","WP2037",169000,2320,0.725
"WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)","WP2813",23300,2120,0.725
"WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits","WP3678",36800,2160,0.726
"WP3874","Canonical and Non-Canonical TGF-B signaling","WP3874",36500,2140,0.726
"WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling","WP732",32600,2170,0.728
"WP4197","The human immune response to tuberculosis","WP4197",49500,2150,0.729
"WP1539","Angiogenesis","WP1539",53400,2220,0.73
"WP4705","Pathways of nucleic acid metabolism and innate immune sensing","WP4705",27700,2130,0.731
"WP4478","LTF danger signal response pathway","WP4478",30600,2180,0.732
"WP4722","Glycerolipids and Glycerophospholipids","WP4722",39600,2200,0.735
"WP2447","Amyotrophic lateral sclerosis (ALS)","WP2447",67500,2250,0.736
"WP382","MAPK Signaling Pathway","WP382",457000,2350,0.739
"WP299","Nuclear Receptors in Lipid Metabolism and Toxicity","WP299",33600,2100,0.742
"WP2290","RalA downstream regulated genes","WP2290",23500,2130,0.747
"WP3858","Toll-like Receptor Signaling related to MyD88","WP3858",59500,2200,0.747
"WP2870","Extracellular vesicle-mediated signaling in recipient cells","WP2870",60200,2230,0.75
"WP2035","Follicle Stimulating Hormone (FSH) signaling pathway","WP2035",47800,2170,0.751
"WP2877","Vitamin D Receptor Pathway","WP2877",270000,2290,0.752
"WP4494","Selective expression of chemokine receptors during T-cell polarization","WP4494",32100,2010,0.757
"WP4153","Degradation pathway of sphingolipids, including diseases","WP4153",15900,1990,0.762
"WP4564","Neural Crest Cell Migration during Development","WP4564",74600,2260,0.762
"WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities","WP3844",66900,2230,0.765
"WP405","Eukaryotic Transcription Initiation","WP405",91000,2220,0.772
"WP400","p38 MAPK Signaling Pathway","WP400",73700,2230,0.777
"WP3945","TYROBP Causal Network","WP3945",118000,2080,0.779
"WP2333","Trans-sulfuration pathway","WP2333",20800,2080,0.781
"WP4685","Melanoma","WP4685",143000,2270,0.781
"WP3937","Microglia Pathogen Phagocytosis Pathway","WP3937",72800,2020,0.782
"WP364","IL-6 signaling pathway","WP364",92200,2250,0.783
"WP4262","Breast cancer pathway","WP4262",280000,2310,0.783
"WP4542","Overview of leukocyte-intrinsic Hippo pathway functions","WP4542",64600,2150,0.783
"WP2805","exRNA mechanism of action and biogenesis","WP2805",9440,1890,0.785
"WP716","Vitamin A and Carotenoid Metabolism","WP716",50300,2190,0.786
"WP2637","Structural Pathway of Interleukin 1 (IL-1)","WP2637",109000,2230,0.787
"WP3651","Pathways Affected in Adenoid Cystic Carcinoma","WP3651",124000,2210,0.795
"WP3286","Copper homeostasis","WP3286",104000,2220,0.797
"WP3853","ERK Pathway in Huntington's Disease","WP3853",26900,2070,0.808
"WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity","WP3969",28800,2060,0.809
"WP4241","Type 2 papillary renal cell carcinoma","WP4241",65500,2180,0.814
"WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders","WP4292",18000,2000,0.816
"WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)","WP4721",41900,2090,0.819
"WP205","IL-7 Signaling Pathway","WP205",52600,2110,0.825
"WP3634","Insulin signalling in human adipocytes (normal condition)","WP3634",16000,2000,0.826
"WP3635","Insulin signalling in human adipocytes (diabetic condition)","WP3635",16000,2000,0.826
"WP4150","Wnt Signaling in Kidney Disease","WP4150",57900,2140,0.827
"WP4479","Supression of HMGB1 mediated inflammation by THBD","WP4479",17300,1930,0.827
"WP22","IL-9 Signaling Pathway","WP22",30300,2020,0.828
"WP2942","DDX1 as a regulatory component of the Drosha microprocessor","WP2942",11100,1840,0.828
"WP313","Signaling of Hepatocyte Growth Factor Receptor","WP313",73400,2160,0.828
"WP4223","Ras Signaling","WP4223",326000,2300,0.828
"WP4582","Cancer immunotherapy by CTLA4 blockade","WP4582",23500,1960,0.829
"WP2034","Leptin signaling pathway","WP2034",167000,2230,0.831
"WP4210","Tryptophan catabolism leading to NAD+ production","WP4210",21700,1970,0.833
"WP288","NLR Proteins","WP288",14800,1860,0.835
"WP366","TGF-beta Signaling Pathway","WP366",290000,2270,0.835
"WP438","Non-homologous end joining","WP438",19800,1980,0.835
"WP2513","Nanoparticle triggered regulated necrosis","WP2513",20800,1890,0.837
"WP4656","Joubert Syndrome","WP4656",154000,2230,0.837
"WP4255","Non-small cell lung cancer","WP4255",150000,2240,0.838
"WP23","B Cell Receptor Signaling Pathway","WP23",204000,2220,0.842
"WP304","Kit receptor signaling pathway","WP304",130000,2200,0.842
"WP1559","TFs Regulate miRNAs related to cardiac hypertrophy","WP1559",13400,1910,0.845
"WP3645","NAD+ biosynthetic pathways","WP3645",35200,2070,0.847
"WP437","EGF/EGFR Signaling Pathway","WP437",349000,2250,0.849
"WP4018","Pathways in clear cell renal cell carcinoma","WP4018",177000,2240,0.85
"WP696","Benzo(a)pyrene metabolism","WP696",11400,1630,0.85
"WP4565","Neural Crest Cell Migration in Cancer","WP4565",79000,2200,0.851
"WP3614","Photodynamic therapy-induced HIF-1 survival signaling","WP3614",71000,2150,0.853
"WP69","T-Cell antigen Receptor (TCR) Signaling Pathway","WP69",174000,2120,0.853
"WP286","IL-3 Signaling Pathway","WP286",96100,2180,0.854
"WP4483","Relationship between inflammation, COX-2 and EGFR","WP4483",45700,2080,0.856
"WP4549","Fragile X Syndrome ","WP4549",209000,2230,0.859
"WP49","IL-2 Signaling Pathway","WP49",87900,2140,0.86
"WP4747","Netrin-UNC5B signaling Pathway","WP4747",95400,2170,0.863
"WP2873","Aryl Hydrocarbon Receptor Pathway","WP2873",65000,2100,0.866
"WP1584","Type II diabetes mellitus","WP1584",27400,1960,0.867
"WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation","WP368",31500,1970,0.867
"WP3303","RAC1/PAK1/p38/MMP2 Pathway","WP3303",136000,2190,0.871
"WP3931","ESC Pluripotency Pathways","WP3931",187000,2250,0.871
"WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway","WP4206",38500,2030,0.873
"WP422","MAPK Cascade","WP422",70400,2130,0.873
"WP3982","miRNA regulation of p53 pathway in prostate cancer","WP3982",47700,2070,0.874
"WP481","Insulin Signaling","WP481",340000,2270,0.874
"WP3934","Leptin and adiponectin","WP3934",14900,1870,0.879
"WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells","WP4301",35800,1990,0.879
"WP4655","Cytosolic DNA-sensing pathway","WP4655",118000,2150,0.879
"WP4159","GABA receptor Signaling","WP4159",25200,1940,0.881
"WP2828","Bladder Cancer","WP2828",81500,2140,0.882
"WP4263","Pancreatic adenocarcinoma pathway","WP4263",188000,2220,0.883
"WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway","WP2018",112000,2160,0.887
"WP75","Toll-like Receptor Signaling Pathway","WP75",170000,2180,0.889
"WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)","WP2453",27800,1850,0.892
"WP4585","Cancer immunotherapy by PD-1 blockade","WP4585",38000,1810,0.892
"WP4561","Cell migration and invasion through p75NTR","WP4561",59200,2110,0.894
"WP691","Tamoxifen metabolism","WP691",7830,1570,0.894
"WP4239","Epithelial to mesenchymal transition in colorectal cancer","WP4239",278000,2190,0.895
"WP106","Alanine and aspartate metabolism","WP106",12100,1720,0.896
"WP4723","Omega-3/Omega-6 FA synthesis","WP4723",20000,1820,0.896
"WP185","Integrin-mediated Cell Adhesion","WP185",188000,2160,0.899
"WP2324","AGE/RAGE pathway","WP2324",138000,2180,0.899
"WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition","WP3859",32500,1910,0.899
"WP325","Triacylglyceride Synthesis","WP325",26000,1860,0.906
"WP363","Wnt Signaling Pathway (Netpath)","WP363",103000,2140,0.91
"WP2572","Primary Focal Segmental Glomerulosclerosis FSGS","WP2572",123000,2110,0.911
"WP4313","Ferroptosis","WP4313",73300,2040,0.915
"WP2261","Signaling Pathways in Glioblastoma","WP2261",176000,2200,0.917
"WP43","Oxidation by Cytochrome P450","WP43",58700,1960,0.917
"WP4136","Fibrin Complement Receptor 3 Signaling Pathway","WP4136",60500,2020,0.918
"WP673","ErbB Signaling Pathway","WP673",176000,2170,0.919
"WP2643","Nanoparticle-mediated activation of receptor signaling","WP2643",54800,1960,0.92
"WP4504","Cysteine and methionine catabolism","WP4504",24200,1860,0.922
"WP453","Inflammatory Response Pathway","WP453",39800,1810,0.922
"WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism","WP4746",141000,2140,0.925
"WP1449","Regulation of toll-like receptor signaling pathway","WP1449",242000,2180,0.926
"WP143","Fatty Acid Beta Oxidation","WP143",53400,1980,0.928
"WP244","Alpha 6 Beta 4 signaling pathway","WP244",65500,1990,0.928
"WP4659","Gastrin Signaling Pathway","WP4659",229000,2180,0.929
"WP3869","Cannabinoid receptor signaling","WP3869",44600,1940,0.933
"WP195","IL-1 signaling pathway","WP195",116000,2110,0.934
"WP3965","Lipid Metabolism Pathway","WP3965",52000,2000,0.934
"WP3981","miRNA regulation of prostate cancer signaling pathways","WP3981",63500,1980,0.935
"WP12","Osteoclast Signaling","WP12",21300,1770,0.937
"WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling","WP1982",138000,2120,0.937
"WP4146","Macrophage markers","WP4146",12200,1350,0.946
"WP100","Glutathione metabolism","WP100",27300,1700,0.949
"WP3413","NOTCH1 regulation of human endothelial cell calcification","WP3413",28900,1810,0.952
"WP111","Electron Transport Chain (OXPHOS system in mitochondria)","WP111",125000,1780,0.956
"WP615","Senescence and Autophagy in Cancer","WP615",199000,2140,0.957
"WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway","WP1433",59400,1860,0.959
"WP4329","miRNAs involvement in the immune response in sepsis","WP4329",62200,1940,0.959
"WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression","WP3879",31300,1740,0.961
"WP4155","Endometrial cancer","WP4155",123000,2080,0.961
"WP3676","BDNF-TrkB Signaling","WP3676",59300,1980,0.962
"WP4352","Ciliary landscape","WP4352",419000,2160,0.962
"WP4536","Genes related to primary cilium development (based on CRISPR)","WP4536",180000,2020,0.968
"WP1471","Target Of Rapamycin (TOR) Signaling","WP1471",65800,1930,0.969
"WP357","Fatty Acid Biosynthesis","WP357",36700,1840,0.969
"WP4396","Nonalcoholic fatty liver disease","WP4396",273000,2020,0.971
"WP4205","MET in type 1 papillary renal cell carcinoma","WP4205",105000,2020,0.972
"WP2509","Nanoparticle triggered autophagic cell death","WP2509",37700,1790,0.978
"WP581","EPO Receptor Signaling","WP581",46000,1840,0.979
"WP2526","PDGF Pathway","WP2526",75100,1920,0.98
"WP692","Sulfation Biotransformation Reaction","WP692",6720,1120,0.983
"WP702","Metapathway biotransformation Phase I and II","WP702",175000,1950,0.983
"WP3915","Angiopoietin Like Protein 8 Regulatory Pathway","WP3915",242000,2070,0.984
"WP4758","Nephrotic syndrome","WP4758",60900,1850,0.984
"WP534","Glycolysis and Gluconeogenesis","WP534",60600,1830,0.984
"WP4217","Ebola Virus Pathway on Host","WP4217",239000,2020,0.985
"WP710","DNA Damage Response (only ATM dependent)","WP710",207000,2070,0.988
"WP4674","Head and Neck Squamous Cell Carcinoma","WP4674",129000,1960,0.991
"WP623","Oxidative phosphorylation","WP623",56200,1520,0.993
"WP4324","Mitochondrial complex I assembly model OXPHOS system","WP4324",69700,1550,0.995
"WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways","WP3680",107000,1950,0.996
"WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway","WP4577",73600,1710,0.998
"WP697","Estrogen metabolism","WP697",7800,867,0.999
"WP4532","Intraflagellar transport proteins binding to dynein","WP4532",30900,1410,1
1 set_id name GENE.SET GLOB.STAT NGLOB.STAT PVAL
2 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation WP1991 39300 4370 0.001
3 WP2023 Cell Differentiation - Index expanded WP2023 43100 3920 0.001
4 WP1602 Nicotine Activity on Dopaminergic Neurons WP1602 40000 3630 0.002
5 WP2029 Cell Differentiation - Index WP2029 25100 4180 0.007
6 WP3996 Ethanol effects on histone modifications WP3996 86700 3100 0.008
7 WP497 Urea cycle and metabolism of amino groups WP497 52400 3280 0.008
8 WP3944 Serotonin and anxiety-related events WP3944 23400 3900 0.009
9 WP2361 Gastric Cancer Network 1 WP2361 83100 3780 0.011
10 WP4545 Oxysterols derived from cholesterol WP4545 35000 3500 0.012
11 WP2848 Differentiation Pathway WP2848 80700 3110 0.013
12 WP247 Small Ligand GPCRs WP247 36000 3600 0.017
13 WP4300 Extracellular vesicles in the crosstalk of cardiac cells WP4300 55600 3270 0.017
14 WP466 DNA Replication WP466 152000 3720 0.019
15 WP289 Myometrial Relaxation and Contraction Pathways WP289 341000 2840 0.022
16 WP236 Adipogenesis WP236 292000 2810 0.026
17 WP179 Cell Cycle WP179 347000 3010 0.027
18 WP2855 Dopaminergic Neurogenesis WP2855 33200 3320 0.028
19 WP3893 Development and heterogeneity of the ILC family WP3893 56400 3130 0.029
20 WP45 G1 to S cell cycle control WP45 194000 3190 0.029
21 WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma WP4337 44300 3410 0.03
22 WP4222 Phosphodiesterases in neuronal function WP4222 93100 3000 0.031
23 WP4760 PKC-gamma calcium signaling pathway in ataxia WP4760 40100 3340 0.033
24 WP35 G Protein Signaling Pathways WP35 220000 2900 0.035
25 WP3958 GPR40 Pathway WP3958 40300 3100 0.035
26 WP4149 White fat cell differentiation WP4149 87000 2900 0.036
27 WP474 Endochondral Ossification WP474 154000 2850 0.041
28 WP2355 Corticotropin-releasing hormone signaling pathway WP2355 199000 2730 0.043
29 WP2446 Retinoblastoma Gene in Cancer WP2446 283000 3290 0.044
30 WP2849 Hematopoietic Stem Cell Differentiation WP2849 124000 2880 0.046
31 WP4589 Major receptors targeted by epinephrine and norepinephrine WP4589 36300 3300 0.046
32 WP3591 Sleep regulation WP3591 40000 3080 0.047
33 WP4584 Biomarkers for pyrimidine metabolism disorders WP4584 37600 3140 0.047
34 WP1992 Genes targeted by miRNAs in adipocytes WP1992 31600 3160 0.048
35 WP2064 Neural Crest Differentiation WP2064 178000 2770 0.048
36 WP383 Striated Muscle Contraction Pathway WP383 76100 3310 0.049
37 WP241 One Carbon Metabolism WP241 75100 3000 0.052
38 WP2516 ATM Signaling Pathway WP2516 109000 2950 0.052
39 WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) WP2815 32200 3220 0.052
40 WP516 Hypertrophy Model WP516 46500 3100 0.053
41 WP58 Monoamine GPCRs WP58 17300 3460 0.054
42 WP4016 DNA IR-damage and cellular response via ATR WP4016 223000 2970 0.055
43 WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) WP2840 156000 2790 0.058
44 WP1601 Fluoropyrimidine Activity WP1601 81100 2900 0.061
45 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways WP706 265000 2650 0.061
46 WP2406 Cardiac Progenitor Differentiation WP2406 86600 2890 0.062
47 WP554 ACE Inhibitor Pathway WP554 36600 3320 0.064
48 WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM WP3959 147000 2820 0.065
49 WP531 DNA Mismatch Repair WP531 67300 3210 0.066
50 WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition WP4240 49900 3330 0.067
51 WP2197 Endothelin Pathways WP2197 66300 2880 0.069
52 WP2525 Trans-sulfuration and one carbon metabolism WP2525 80900 2890 0.069
53 WP536 Calcium Regulation in the Cardiac Cell WP536 302000 2820 0.069
54 WP727 Monoamine Transport WP727 49900 2930 0.07
55 WP1530 miRNA Regulation of DNA Damage Response WP1530 179000 2800 0.072
56 WP3611 Photodynamic therapy-induced AP-1 survival signaling. WP3611 128000 2790 0.075
57 WP1423 Ganglio Sphingolipid Metabolism WP1423 25100 3140 0.078
58 WP707 DNA Damage Response WP707 172000 2780 0.078
59 WP3299 let-7 inhibition of ES cell reprogramming WP3299 16900 3380 0.085
60 WP1528 Physiological and Pathological Hypertrophy of the Heart WP1528 68400 2850 0.086
61 WP384 Apoptosis Modulation by HSP70 WP384 52400 2910 0.089
62 WP2431 Spinal Cord Injury WP2431 242000 2690 0.09
63 WP3599 Transcription factor regulation in adipogenesis WP3599 54200 2850 0.092
64 WP3947 Serotonin and anxiety WP3947 22000 3150 0.093
65 WP558 Complement and Coagulation Cascades WP558 114000 2910 0.099
66 WP3995 Prion disease pathway WP3995 84900 2740 0.1
67 WP4752 Base Excision Repair WP4752 85900 2860 0.105
68 WP4204 Tumor suppressor activity of SMARCB1 WP4204 72400 2790 0.107
69 WP4259 Disorders of Folate Metabolism and Transport WP4259 33100 3010 0.108
70 WP2806 Human Complement System WP2806 177000 2820 0.111
71 WP560 TGF-beta Receptor Signaling WP560 123000 2680 0.113
72 WP2276 Glial Cell Differentiation WP2276 16100 3220 0.119
73 WP3580 Methionine De Novo and Salvage Pathway WP3580 52600 2770 0.119
74 WP4698 Vitamin D-sensitive calcium signaling in depression WP4698 60500 2750 0.125
75 WP2113 Type III interferon signaling WP2113 19400 3240 0.127
76 WP136 Phase I biotransformations, non P450 WP136 15500 3110 0.13
77 WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) WP2814 34600 2880 0.13
78 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling WP3679 27700 3070 0.133
79 WP3892 Development of pulmonary dendritic cells and macrophage subsets WP3892 31600 3160 0.134
80 WP3287 Overview of nanoparticle effects WP3287 41700 2780 0.136
81 WP4225 Pyrimidine metabolism and related diseases WP4225 35000 2910 0.136
82 WP170 Nuclear Receptors WP170 78400 2700 0.14
83 WP2874 Liver X Receptor Pathway WP2874 16100 3220 0.14
84 WP4571 Urea cycle and related diseases WP4571 17900 2980 0.142
85 WP3640 Imatinib and Chronic Myeloid Leukemia WP3640 55400 2770 0.149
86 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway WP2032 162000 2610 0.15
87 WP2363 Gastric Cancer Network 2 WP2363 81200 2800 0.151
88 WP4022 Pyrimidine metabolism WP4022 203000 2640 0.152
89 WP2369 Histone Modifications WP2369 81700 2720 0.155
90 WP206 Fatty Acid Omega Oxidation WP206 16400 3280 0.157
91 WP2879 Farnesoid X Receptor Pathway WP2879 21000 3000 0.16
92 WP3875 ATR Signaling WP3875 23700 2960 0.16
93 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis WP2011 44700 2790 0.164
94 WP2895 Differentiation of white and brown adipocyte WP2895 49400 2750 0.164
95 WP3584 MECP2 and Associated Rett Syndrome WP3584 133000 2600 0.164
96 WP4658 Small cell lung cancer WP4658 228000 2570 0.166
97 WP1742 TP53 Network WP1742 49900 2770 0.167
98 WP2858 Ectoderm Differentiation WP2858 285000 2570 0.167
99 WP4224 Purine metabolism and related disorders WP4224 51400 2710 0.168
100 WP3613 Photodynamic therapy-induced unfolded protein response WP3613 65000 2710 0.17
101 WP2059 Alzheimers Disease WP2059 179000 2590 0.179
102 WP545 Complement Activation WP545 44800 2990 0.18
103 WP2267 Synaptic Vesicle Pathway WP2267 81500 2630 0.181
104 WP1971 Integrated Cancer Pathway WP1971 115000 2670 0.183
105 WP3624 Lung fibrosis WP3624 112000 2660 0.185
106 WP4754 IL-18 signaling pathway WP4754 557000 2510 0.185
107 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation WP3876 30300 2760 0.193
108 WP4756 Renin Angiotensin Aldosterone System (RAAS) WP4756 75400 2690 0.193
109 WP2878 PPAR Alpha Pathway WP2878 43300 2710 0.196
110 WP1434 Osteopontin Signaling WP1434 36500 2810 0.197
111 WP698 Glucuronidation WP698 25100 2790 0.197
112 WP176 Folate Metabolism WP176 116000 2630 0.198
113 WP465 Tryptophan metabolism WP465 71700 2660 0.2
114 WP186 Homologous recombination WP186 33400 2780 0.201
115 WP3594 Circadian rhythm related genes WP3594 349000 2530 0.202
116 WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement WP4560 47500 2790 0.208
117 WP4312 Rett syndrome causing genes WP4312 96900 2620 0.215
118 WP3656 Interleukin-1 Induced Activation of NF-kappa-B WP3656 27400 2740 0.217
119 WP4288 MTHFR deficiency WP4288 51800 2720 0.219
120 WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) WP4719 56000 2670 0.222
121 WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS WP4304 43800 2740 0.223
122 WP3529 Zinc homeostasis WP3529 63800 2660 0.224
123 WP2338 miRNA Biogenesis WP2338 17000 2840 0.225
124 WP3585 Cytosine methylation WP3585 21900 2730 0.225
125 WP4495 IL-10 Anti-inflammatory Signaling Pathway WP4495 30000 2720 0.225
126 WP2007 Iron metabolism in placenta WP2007 22200 2770 0.227
127 WP4249 Hedgehog Signaling Pathway WP4249 88300 2600 0.227
128 WP98 Prostaglandin Synthesis and Regulation WP98 97200 2630 0.227
129 WP2865 IL1 and megakaryocytes in obesity WP2865 56300 2680 0.229
130 WP1422 Sphingolipid pathway WP1422 62800 2620 0.233
131 WP4290 Metabolic reprogramming in colon cancer WP4290 102000 2620 0.234
132 WP4493 Cells and Molecules involved in local acute inflammatory response WP4493 36600 2810 0.236
133 WP117 GPCRs, Other WP117 58000 2640 0.24
134 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway WP3670 44800 2640 0.243
135 WP24 Peptide GPCRs WP24 56100 2670 0.246
136 WP1545 miRNAs involved in DNA damage response WP1545 37500 2680 0.248
137 WP3930 EDA Signalling in Hair Follicle Development WP3930 24800 2760 0.248
138 WP138 Androgen receptor signaling pathway WP138 207000 2530 0.25
139 WP34 Ovarian Infertility Genes WP34 44700 2630 0.25
140 WP4629 Computational Model of Aerobic Glycolysis WP4629 31700 2880 0.25
141 WP4286 Genotoxicity pathway WP4286 125000 2560 0.255
142 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex WP3657 50700 2670 0.256
143 WP2038 Regulation of Microtubule Cytoskeleton WP2038 108000 2570 0.27
144 WP2507 Nanomaterial induced apoptosis WP2507 49700 2610 0.272
145 WP3963 Mevalonate pathway WP3963 19700 2810 0.272
146 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway WP3877 36900 2640 0.273
147 WP4357 NRF2-ARE regulation WP4357 56900 2590 0.273
148 WP530 Cytokines and Inflammatory Response WP530 37100 2650 0.277
149 WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) WP2817 64100 2570 0.278
150 WP1589 Folate-Alcohol and Cancer Pathway Hypotheses WP1589 21700 2710 0.285
151 WP430 Statin Pathway WP430 39400 2620 0.285
152 WP4673 Genes involved in male infertility WP4673 212000 2490 0.286
153 WP4535 Envelope proteins and their potential roles in EDMD physiopathology WP4535 102000 2540 0.288
154 WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma WP4553 29300 2660 0.289
155 WP3941 Oxidative Damage WP3941 94800 2560 0.29
156 WP4481 Resistin as a regulator of inflammation WP4481 72200 2580 0.29
157 WP3942 PPAR signaling pathway WP3942 113000 2500 0.293
158 WP428 Wnt Signaling WP428 233000 2500 0.294
159 WP4172 PI3K-Akt Signaling Pathway WP4172 622000 2470 0.296
160 WP1772 Apoptosis Modulation and Signaling WP1772 197000 2500 0.298
161 WP1531 Vitamin D Metabolism WP1531 18900 2700 0.301
162 WP1984 Integrated Breast Cancer Pathway WP1984 355000 2490 0.301
163 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation WP314 102000 2540 0.301
164 WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 WP4341 146000 2520 0.302
165 WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases WP4518 13600 2720 0.304
166 WP1591 Heart Development WP1591 75600 2520 0.316
167 WP3407 FTO Obesity Variant Mechanism WP3407 18900 2700 0.319
168 WP129 Matrix Metalloproteinases WP129 57000 2590 0.325
169 WP1455 Serotonin Transporter Activity WP1455 21000 2630 0.325
170 WP4462 Platelet-mediated interactions with vascular and circulating cells WP4462 39600 2640 0.329
171 WP4298 Viral Acute Myocarditis WP4298 174000 2480 0.333
172 WP254 Apoptosis WP254 198000 2480 0.335
173 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy WP2118 142000 2540 0.336
174 WP3655 Hypothetical Craniofacial Development Pathway WP3655 16200 2700 0.336
175 WP107 Translation Factors WP107 118000 2520 0.337
176 WP167 Eicosanoid Synthesis WP167 45600 2530 0.34
177 WP3871 Valproic acid pathway WP3871 21100 2640 0.341
178 WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging WP4186 15800 2630 0.341
179 WP3972 PDGFR-beta pathway WP3972 73500 2540 0.347
180 WP4558 Overview of interferons-mediated signaling pathway WP4558 36000 2570 0.347
181 WP2853 Endoderm Differentiation WP2853 275000 2450 0.348
182 WP3630 NAD metabolism, sirtuins and aging WP3630 26000 2600 0.349
183 WP3878 ATM Signaling Network in Development and Disease WP3878 103000 2510 0.35
184 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein WP3872 50400 2520 0.352
185 WP3888 VEGFA-VEGFR2 Signaling Pathway WP3888 986000 2450 0.358
186 WP4583 Biomarkers for urea cycle disorders WP4583 21000 2620 0.358
187 WP197 Cholesterol Biosynthesis Pathway WP197 35700 2550 0.36
188 WP26 Signal Transduction of S1P Receptor WP26 60900 2540 0.361
189 WP4148 Splicing factor NOVA regulated synaptic proteins WP4148 77400 2500 0.364
190 WP585 Interferon type I signaling pathways WP585 129000 2480 0.364
191 WP306 Focal Adhesion WP306 426000 2460 0.366
192 WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome WP4320 55400 2520 0.367
193 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling WP734 40800 2550 0.368
194 WP4321 Thermogenesis WP4321 223000 2470 0.369
195 WP3595 mir-124 predicted interactions with cell cycle and differentiation WP3595 15800 2630 0.371
196 WP4538 Regulatory circuits of the STAT3 signaling pathway WP4538 166000 2480 0.371
197 WP1541 Energy Metabolism WP1541 105000 2500 0.378
198 WP2371 Parkinsons Disease Pathway WP2371 77000 2480 0.378
199 WP4211 Transcriptional cascade regulating adipogenesis WP4211 32800 2530 0.38
200 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR WP3414 67700 2510 0.381
201 WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) WP4718 102000 2490 0.382
202 WP4725 Sphingolipid Metabolism (general overview) WP4725 49800 2490 0.382
203 WP272 Blood Clotting Cascade WP272 30500 2540 0.383
204 WP3998 Prader-Willi and Angelman Syndrome WP3998 74300 2480 0.383
205 WP2359 Parkin-Ubiquitin Proteasomal System pathway WP2359 145000 2460 0.385
206 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer WP2864 123000 2460 0.386
207 WP411 mRNA Processing WP411 3e+05 2460 0.386
208 WP4147 PTF1A related regulatory pathway WP4147 12900 2580 0.387
209 WP3527 Preimplantation Embryo WP3527 77300 2490 0.392
210 WP322 Osteoblast Signaling WP322 18300 2610 0.393
211 WP4482 Vitamin D in inflammatory diseases WP4482 52400 2500 0.398
212 WP4753 Nucleotide Excision Repair WP4753 106000 2460 0.399
213 WP561 Heme Biosynthesis WP561 20000 2500 0.4
214 WP4236 Disorders of the Krebs cycle WP4236 17500 2500 0.406
215 WP3971 Role of Osx and miRNAs in tooth development WP3971 24700 2470 0.408
216 WP4523 Classical pathway of steroidogenesis, including diseases WP4523 12800 2550 0.409
217 WP410 Exercise-induced Circadian Regulation WP410 109000 2480 0.41
218 WP4533 Transcription co-factors SKI and SKIL protein partners WP4533 45100 2510 0.411
219 WP53 ID signaling pathway WP53 32400 2490 0.417
220 WP3644 NAD+ metabolism WP3644 34700 2480 0.422
221 WP3926 ApoE and miR-146 in inflammation and atherosclerosis WP3926 20000 2500 0.422
222 WP1946 Cori Cycle WP1946 34900 2490 0.425
223 WP262 EBV LMP1 signaling WP262 49200 2460 0.426
224 WP500 Glycogen Synthesis and Degradation WP500 88500 2460 0.426
225 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness WP3301 32500 2500 0.427
226 WP3617 Photodynamic therapy-induced NF-kB survival signaling WP3617 72700 2420 0.428
227 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling WP3850 71500 2470 0.428
228 WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment WP4480 20100 2520 0.428
229 WP15 Selenium Micronutrient Network WP15 121000 2430 0.431
230 WP3596 miR-517 relationship with ARCN1 and USP1 WP3596 12500 2500 0.434
231 WP183 Proteasome Degradation WP183 141000 2440 0.436
232 WP2881 Estrogen Receptor Pathway WP2881 24600 2460 0.439
233 WP2875 Constitutive Androstane Receptor Pathway WP2875 41400 2440 0.443
234 WP4008 NO/cGMP/PKG mediated Neuroprotection WP4008 61700 2470 0.444
235 WP4539 Synaptic signaling pathways associated with autism spectrum disorder WP4539 95600 2450 0.445
236 WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma WP4336 167000 2420 0.447
237 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer WP2291 36300 2420 0.451
238 WP455 GPCRs, Class A Rhodopsin-like WP455 141000 2430 0.454
239 WP2485 NAD Biosynthesis II (from tryptophan) WP2485 14800 2470 0.455
240 WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation WP4767 58400 2430 0.461
241 WP4521 Glycosylation and related congenital defects WP4521 60500 2420 0.479
242 WP3672 LncRNA-mediated mechanisms of therapeutic resistance WP3672 17100 2440 0.48
243 WP2586 Aryl Hydrocarbon Receptor Netpath WP2586 96900 2420 0.482
244 WP2583 T-Cell Receptor and Co-stimulatory Signaling WP2583 65000 2410 0.49
245 WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 WP4269 21700 2410 0.499
246 WP4726 Sphingolipid Metabolism (integrated pathway) WP4726 50000 2380 0.507
247 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase WP678 11900 2380 0.512
248 WP3298 Melatonin metabolism and effects WP3298 62600 2410 0.515
249 WP1533 Vitamin B12 Metabolism WP1533 71500 2380 0.516
250 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia WP3658 50100 2390 0.516
251 WP3927 BMP Signaling Pathway in Eyelid Development WP3927 38100 2380 0.516
252 WP3935 Leptin Insulin Overlap WP3935 33600 2400 0.516
253 WP2332 Interleukin-11 Signaling Pathway WP2332 96300 2410 0.517
254 WP524 G13 Signaling Pathway WP524 83800 2390 0.517
255 WP4331 Neovascularisation processes WP4331 89100 2410 0.519
256 WP4657 22q11.2 Deletion Syndrome WP4657 140000 2410 0.52
257 WP2911 miRNA targets in ECM and membrane receptors WP2911 51000 2320 0.521
258 WP1403 AMP-activated Protein Kinase (AMPK) Signaling WP1403 135000 2400 0.526
259 WP2112 IL17 signaling pathway WP2112 65000 2410 0.526
260 WP28 Selenium Metabolism and Selenoproteins WP28 66800 2380 0.528
261 WP408 Oxidative Stress WP408 68400 2360 0.528
262 WP4540 Pathways Regulating Hippo Signaling WP4540 190000 2400 0.535
263 WP268 Notch Signaling WP268 95800 2390 0.536
264 WP2857 Mesodermal Commitment Pathway WP2857 278000 2400 0.536
265 WP4724 Omega-9 FA synthesis WP4724 28000 2330 0.545
266 WP229 Irinotecan Pathway WP229 16300 2330 0.55
267 WP3929 Chemokine signaling pathway WP3929 296000 2390 0.551
268 WP4507 Molybdenum cofactor (Moco) biosynthesis WP4507 13900 2320 0.553
269 WP3646 Hepatitis C and Hepatocellular Carcinoma WP3646 104000 2370 0.558
270 WP501 GPCRs, Class C Metabotropic glutamate, pheromone WP501 11600 2320 0.564
271 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation WP1425 23000 2300 0.57
272 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway WP2203 107000 2370 0.572
273 WP3 Phytochemical activity on NRF2 transcriptional activation WP3 32700 2340 0.572
274 WP80 Nucleotide GPCRs WP80 18600 2320 0.572
275 WP311 Synthesis and Degradation of Ketone Bodies WP311 11400 2280 0.573
276 WP4586 Metabolism of alpha-linolenic acid WP4586 13700 2280 0.575
277 WP2636 Common Pathways Underlying Drug Addiction WP2636 56100 2340 0.576
278 WP2876 Pregnane X Receptor pathway WP2876 41800 2320 0.576
279 WP4742 Ketogenesis and Ketolysis WP4742 18400 2300 0.577
280 WP3851 TLR4 Signaling and Tolerance WP3851 58900 2360 0.584
281 WP2916 Interactome of polycomb repressive complex 2 (PRC2) WP2916 37400 2330 0.586
282 WP4191 Caloric restriction and aging WP4191 18500 2310 0.587
283 WP134 Pentose Phosphate Metabolism WP134 15400 2200 0.589
284 WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway WP3932 581000 2390 0.589
285 WP395 IL-4 Signaling Pathway WP395 125000 2360 0.592
286 WP2272 Pathogenic Escherichia coli infection WP2272 110000 2330 0.594
287 WP704 Methylation Pathways WP704 16100 2300 0.595
288 WP399 Wnt Signaling Pathway and Pluripotency WP399 204000 2370 0.596
289 WP4541 Hippo-Merlin Signaling Dysregulation WP4541 222000 2360 0.597
290 WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma WP3593 15700 2250 0.599
291 WP47 Hedgehog Signaling Pathway Netpath WP47 27800 2320 0.599
292 WP61 Notch Signaling Pathway Netpath WP61 134000 2350 0.599
293 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway WP2036 94000 2350 0.605
294 WP3967 miR-509-3p alteration of YAP1/ECM axis WP3967 38200 2240 0.608
295 WP2249 Metastatic brain tumor WP2249 13300 2220 0.61
296 WP4141 PI3K/AKT/mTOR - VitD3 Signalling WP4141 44100 2320 0.611
297 WP4537 Hippo-Yap signaling pathway WP4537 50700 2300 0.613
298 WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer WP4258 179000 2360 0.614
299 WP2436 Dopamine metabolism WP2436 20400 2260 0.616
300 WP3940 One carbon metabolism and related pathways WP3940 91100 2340 0.617
301 WP51 Regulation of Actin Cytoskeleton WP51 275000 2350 0.62
302 WP4595 Urea cycle and associated pathways WP4595 37100 2320 0.625
303 WP4271 Vitamin B12 Disorders WP4271 20500 2280 0.627
304 WP2854 Gene regulatory network modelling somitogenesis WP2854 13200 2200 0.628
305 WP2456 HIF1A and PPARG regulation of glycolysis WP2456 13100 2180 0.63
306 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ WP3849 27000 2250 0.631
307 WP404 Nucleotide Metabolism WP404 40400 2250 0.632
308 WP3933 Kennedy pathway from Sphingolipids WP3933 27500 2290 0.639
309 WP477 Cytoplasmic Ribosomal Proteins WP477 167000 1960 0.64
310 WP3300 Dual hijack model of Vif in HIV infection WP3300 13000 2160 0.644
311 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway WP2380 290000 2360 0.65
312 WP1544 MicroRNAs in cardiomyocyte hypertrophy WP1544 179000 2350 0.653
313 WP2533 Glycerophospholipid Biosynthetic Pathway WP2533 56900 2270 0.653
314 WP3943 Robo4 and VEGF Signaling Pathways Crosstalk WP3943 13100 2190 0.653
315 WP4496 Signal transduction through IL1R WP4496 68800 2290 0.653
316 WP712 Estrogen signaling pathway WP712 47900 2280 0.656
317 WP4566 Translation inhibitors in chronically activated PDGFRA cells WP4566 104000 2320 0.657
318 WP4562 Canonical NF-KB pathway WP4562 17500 2190 0.667
319 WP4389 Bile Acids synthesis and enterohepatic circulation WP4389 10600 2110 0.668
320 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds WP3664 35900 2250 0.669
321 WP4297 Thiamine metabolic pathways WP4297 17600 2200 0.67
322 WP619 Type II interferon signaling (IFNG) WP619 67600 2180 0.672
323 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease WP3668 52000 2260 0.677
324 WP391 Mitochondrial Gene Expression WP391 35700 2230 0.678
325 WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms WP4534 97900 2280 0.678
326 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling WP3612 46100 2200 0.679
327 WP1424 Globo Sphingolipid Metabolism WP1424 44700 2230 0.68
328 WP4559 Interactions between immune cells and microRNAs in tumor microenvironment WP4559 53000 2210 0.681
329 WP2795 Cardiac Hypertrophic Response WP2795 119000 2330 0.683
330 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer WP2868 10200 2040 0.684
331 WP127 IL-5 Signaling Pathway WP127 87500 2300 0.687
332 WP3925 Amino Acid metabolism WP3925 151000 2290 0.688
333 WP231 TNF alpha Signaling Pathway WP231 204000 2320 0.69
334 WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway WP3865 117000 2300 0.694
335 WP4522 Metabolic pathway of LDL, HDL and TG, including diseases WP4522 19300 2150 0.696
336 WP2882 Nuclear Receptors Meta-Pathway WP2882 516000 2330 0.698
337 WP4666 Hepatitis B infection WP4666 305000 2340 0.699
338 WP78 TCA Cycle (aka Krebs or citric acid cycle) WP78 38300 2130 0.701
339 WP4792 Purine metabolism WP4792 23800 2160 0.706
340 WP4216 Chromosomal and microsatellite instability in colorectal cancer WP4216 165000 2320 0.709
341 WP2374 Oncostatin M Signaling Pathway WP2374 147000 2300 0.71
342 WP4142 Metabolism of Spingolipids in ER and Golgi apparatus WP4142 32300 2150 0.714
343 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection WP3863 112000 2240 0.715
344 WP2328 Allograft Rejection WP2328 131000 2120 0.721
345 WP3845 Canonical and Non-canonical Notch signaling WP3845 49200 2240 0.721
346 WP2884 NRF2 pathway WP2884 218000 2270 0.722
347 WP4519 Cerebral Organic Acidurias, including diseases WP4519 14500 2080 0.723
348 WP2037 Prolactin Signaling Pathway WP2037 169000 2320 0.725
349 WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) WP2813 23300 2120 0.725
350 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits WP3678 36800 2160 0.726
351 WP3874 Canonical and Non-Canonical TGF-B signaling WP3874 36500 2140 0.726
352 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling WP732 32600 2170 0.728
353 WP4197 The human immune response to tuberculosis WP4197 49500 2150 0.729
354 WP1539 Angiogenesis WP1539 53400 2220 0.73
355 WP4705 Pathways of nucleic acid metabolism and innate immune sensing WP4705 27700 2130 0.731
356 WP4478 LTF danger signal response pathway WP4478 30600 2180 0.732
357 WP4722 Glycerolipids and Glycerophospholipids WP4722 39600 2200 0.735
358 WP2447 Amyotrophic lateral sclerosis (ALS) WP2447 67500 2250 0.736
359 WP382 MAPK Signaling Pathway WP382 457000 2350 0.739
360 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity WP299 33600 2100 0.742
361 WP2290 RalA downstream regulated genes WP2290 23500 2130 0.747
362 WP3858 Toll-like Receptor Signaling related to MyD88 WP3858 59500 2200 0.747
363 WP2870 Extracellular vesicle-mediated signaling in recipient cells WP2870 60200 2230 0.75
364 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway WP2035 47800 2170 0.751
365 WP2877 Vitamin D Receptor Pathway WP2877 270000 2290 0.752
366 WP4494 Selective expression of chemokine receptors during T-cell polarization WP4494 32100 2010 0.757
367 WP4153 Degradation pathway of sphingolipids, including diseases WP4153 15900 1990 0.762
368 WP4564 Neural Crest Cell Migration during Development WP4564 74600 2260 0.762
369 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities WP3844 66900 2230 0.765
370 WP405 Eukaryotic Transcription Initiation WP405 91000 2220 0.772
371 WP400 p38 MAPK Signaling Pathway WP400 73700 2230 0.777
372 WP3945 TYROBP Causal Network WP3945 118000 2080 0.779
373 WP2333 Trans-sulfuration pathway WP2333 20800 2080 0.781
374 WP4685 Melanoma WP4685 143000 2270 0.781
375 WP3937 Microglia Pathogen Phagocytosis Pathway WP3937 72800 2020 0.782
376 WP364 IL-6 signaling pathway WP364 92200 2250 0.783
377 WP4262 Breast cancer pathway WP4262 280000 2310 0.783
378 WP4542 Overview of leukocyte-intrinsic Hippo pathway functions WP4542 64600 2150 0.783
379 WP2805 exRNA mechanism of action and biogenesis WP2805 9440 1890 0.785
380 WP716 Vitamin A and Carotenoid Metabolism WP716 50300 2190 0.786
381 WP2637 Structural Pathway of Interleukin 1 (IL-1) WP2637 109000 2230 0.787
382 WP3651 Pathways Affected in Adenoid Cystic Carcinoma WP3651 124000 2210 0.795
383 WP3286 Copper homeostasis WP3286 104000 2220 0.797
384 WP3853 ERK Pathway in Huntington's Disease WP3853 26900 2070 0.808
385 WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity WP3969 28800 2060 0.809
386 WP4241 Type 2 papillary renal cell carcinoma WP4241 65500 2180 0.814
387 WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders WP4292 18000 2000 0.816
388 WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) WP4721 41900 2090 0.819
389 WP205 IL-7 Signaling Pathway WP205 52600 2110 0.825
390 WP3634 Insulin signalling in human adipocytes (normal condition) WP3634 16000 2000 0.826
391 WP3635 Insulin signalling in human adipocytes (diabetic condition) WP3635 16000 2000 0.826
392 WP4150 Wnt Signaling in Kidney Disease WP4150 57900 2140 0.827
393 WP4479 Supression of HMGB1 mediated inflammation by THBD WP4479 17300 1930 0.827
394 WP22 IL-9 Signaling Pathway WP22 30300 2020 0.828
395 WP2942 DDX1 as a regulatory component of the Drosha microprocessor WP2942 11100 1840 0.828
396 WP313 Signaling of Hepatocyte Growth Factor Receptor WP313 73400 2160 0.828
397 WP4223 Ras Signaling WP4223 326000 2300 0.828
398 WP4582 Cancer immunotherapy by CTLA4 blockade WP4582 23500 1960 0.829
399 WP2034 Leptin signaling pathway WP2034 167000 2230 0.831
400 WP4210 Tryptophan catabolism leading to NAD+ production WP4210 21700 1970 0.833
401 WP288 NLR Proteins WP288 14800 1860 0.835
402 WP366 TGF-beta Signaling Pathway WP366 290000 2270 0.835
403 WP438 Non-homologous end joining WP438 19800 1980 0.835
404 WP2513 Nanoparticle triggered regulated necrosis WP2513 20800 1890 0.837
405 WP4656 Joubert Syndrome WP4656 154000 2230 0.837
406 WP4255 Non-small cell lung cancer WP4255 150000 2240 0.838
407 WP23 B Cell Receptor Signaling Pathway WP23 204000 2220 0.842
408 WP304 Kit receptor signaling pathway WP304 130000 2200 0.842
409 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy WP1559 13400 1910 0.845
410 WP3645 NAD+ biosynthetic pathways WP3645 35200 2070 0.847
411 WP437 EGF/EGFR Signaling Pathway WP437 349000 2250 0.849
412 WP4018 Pathways in clear cell renal cell carcinoma WP4018 177000 2240 0.85
413 WP696 Benzo(a)pyrene metabolism WP696 11400 1630 0.85
414 WP4565 Neural Crest Cell Migration in Cancer WP4565 79000 2200 0.851
415 WP3614 Photodynamic therapy-induced HIF-1 survival signaling WP3614 71000 2150 0.853
416 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway WP69 174000 2120 0.853
417 WP286 IL-3 Signaling Pathway WP286 96100 2180 0.854
418 WP4483 Relationship between inflammation, COX-2 and EGFR WP4483 45700 2080 0.856
419 WP4549 Fragile X Syndrome WP4549 209000 2230 0.859
420 WP49 IL-2 Signaling Pathway WP49 87900 2140 0.86
421 WP4747 Netrin-UNC5B signaling Pathway WP4747 95400 2170 0.863
422 WP2873 Aryl Hydrocarbon Receptor Pathway WP2873 65000 2100 0.866
423 WP1584 Type II diabetes mellitus WP1584 27400 1960 0.867
424 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation WP368 31500 1970 0.867
425 WP3303 RAC1/PAK1/p38/MMP2 Pathway WP3303 136000 2190 0.871
426 WP3931 ESC Pluripotency Pathways WP3931 187000 2250 0.871
427 WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway WP4206 38500 2030 0.873
428 WP422 MAPK Cascade WP422 70400 2130 0.873
429 WP3982 miRNA regulation of p53 pathway in prostate cancer WP3982 47700 2070 0.874
430 WP481 Insulin Signaling WP481 340000 2270 0.874
431 WP3934 Leptin and adiponectin WP3934 14900 1870 0.879
432 WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells WP4301 35800 1990 0.879
433 WP4655 Cytosolic DNA-sensing pathway WP4655 118000 2150 0.879
434 WP4159 GABA receptor Signaling WP4159 25200 1940 0.881
435 WP2828 Bladder Cancer WP2828 81500 2140 0.882
436 WP4263 Pancreatic adenocarcinoma pathway WP4263 188000 2220 0.883
437 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway WP2018 112000 2160 0.887
438 WP75 Toll-like Receptor Signaling Pathway WP75 170000 2180 0.889
439 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) WP2453 27800 1850 0.892
440 WP4585 Cancer immunotherapy by PD-1 blockade WP4585 38000 1810 0.892
441 WP4561 Cell migration and invasion through p75NTR WP4561 59200 2110 0.894
442 WP691 Tamoxifen metabolism WP691 7830 1570 0.894
443 WP4239 Epithelial to mesenchymal transition in colorectal cancer WP4239 278000 2190 0.895
444 WP106 Alanine and aspartate metabolism WP106 12100 1720 0.896
445 WP4723 Omega-3/Omega-6 FA synthesis WP4723 20000 1820 0.896
446 WP185 Integrin-mediated Cell Adhesion WP185 188000 2160 0.899
447 WP2324 AGE/RAGE pathway WP2324 138000 2180 0.899
448 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition WP3859 32500 1910 0.899
449 WP325 Triacylglyceride Synthesis WP325 26000 1860 0.906
450 WP363 Wnt Signaling Pathway (Netpath) WP363 103000 2140 0.91
451 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS WP2572 123000 2110 0.911
452 WP4313 Ferroptosis WP4313 73300 2040 0.915
453 WP2261 Signaling Pathways in Glioblastoma WP2261 176000 2200 0.917
454 WP43 Oxidation by Cytochrome P450 WP43 58700 1960 0.917
455 WP4136 Fibrin Complement Receptor 3 Signaling Pathway WP4136 60500 2020 0.918
456 WP673 ErbB Signaling Pathway WP673 176000 2170 0.919
457 WP2643 Nanoparticle-mediated activation of receptor signaling WP2643 54800 1960 0.92
458 WP4504 Cysteine and methionine catabolism WP4504 24200 1860 0.922
459 WP453 Inflammatory Response Pathway WP453 39800 1810 0.922
460 WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism WP4746 141000 2140 0.925
461 WP1449 Regulation of toll-like receptor signaling pathway WP1449 242000 2180 0.926
462 WP143 Fatty Acid Beta Oxidation WP143 53400 1980 0.928
463 WP244 Alpha 6 Beta 4 signaling pathway WP244 65500 1990 0.928
464 WP4659 Gastrin Signaling Pathway WP4659 229000 2180 0.929
465 WP3869 Cannabinoid receptor signaling WP3869 44600 1940 0.933
466 WP195 IL-1 signaling pathway WP195 116000 2110 0.934
467 WP3965 Lipid Metabolism Pathway WP3965 52000 2000 0.934
468 WP3981 miRNA regulation of prostate cancer signaling pathways WP3981 63500 1980 0.935
469 WP12 Osteoclast Signaling WP12 21300 1770 0.937
470 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling WP1982 138000 2120 0.937
471 WP4146 Macrophage markers WP4146 12200 1350 0.946
472 WP100 Glutathione metabolism WP100 27300 1700 0.949
473 WP3413 NOTCH1 regulation of human endothelial cell calcification WP3413 28900 1810 0.952
474 WP111 Electron Transport Chain (OXPHOS system in mitochondria) WP111 125000 1780 0.956
475 WP615 Senescence and Autophagy in Cancer WP615 199000 2140 0.957
476 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway WP1433 59400 1860 0.959
477 WP4329 miRNAs involvement in the immune response in sepsis WP4329 62200 1940 0.959
478 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression WP3879 31300 1740 0.961
479 WP4155 Endometrial cancer WP4155 123000 2080 0.961
480 WP3676 BDNF-TrkB Signaling WP3676 59300 1980 0.962
481 WP4352 Ciliary landscape WP4352 419000 2160 0.962
482 WP4536 Genes related to primary cilium development (based on CRISPR) WP4536 180000 2020 0.968
483 WP1471 Target Of Rapamycin (TOR) Signaling WP1471 65800 1930 0.969
484 WP357 Fatty Acid Biosynthesis WP357 36700 1840 0.969
485 WP4396 Nonalcoholic fatty liver disease WP4396 273000 2020 0.971
486 WP4205 MET in type 1 papillary renal cell carcinoma WP4205 105000 2020 0.972
487 WP2509 Nanoparticle triggered autophagic cell death WP2509 37700 1790 0.978
488 WP581 EPO Receptor Signaling WP581 46000 1840 0.979
489 WP2526 PDGF Pathway WP2526 75100 1920 0.98
490 WP692 Sulfation Biotransformation Reaction WP692 6720 1120 0.983
491 WP702 Metapathway biotransformation Phase I and II WP702 175000 1950 0.983
492 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway WP3915 242000 2070 0.984
493 WP4758 Nephrotic syndrome WP4758 60900 1850 0.984
494 WP534 Glycolysis and Gluconeogenesis WP534 60600 1830 0.984
495 WP4217 Ebola Virus Pathway on Host WP4217 239000 2020 0.985
496 WP710 DNA Damage Response (only ATM dependent) WP710 207000 2070 0.988
497 WP4674 Head and Neck Squamous Cell Carcinoma WP4674 129000 1960 0.991
498 WP623 Oxidative phosphorylation WP623 56200 1520 0.993
499 WP4324 Mitochondrial complex I assembly model OXPHOS system WP4324 69700 1550 0.995
500 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways WP3680 107000 1950 0.996
501 WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway WP4577 73600 1710 0.998
502 WP697 Estrogen metabolism WP697 7800 867 0.999
503 WP4532 Intraflagellar transport proteins binding to dynein WP4532 30900 1410 1

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