"set_id","name","ID","Name","Size","Coverage","TDP.bound","TDP.estimate","SC.adjP","Comp.adjP" "WP1600","Nicotine Metabolism",38,"WP1600",6,0.17,1,1,3.39506009152496e-24,3.39506009152496e-24 "WP2276","Glial Cell Differentiation",88,"WP2276",8,0.62,0.4,0.4,7.83386153710323e-26,5.70447887867626e-23 "WP4030","SCFA and skeletal muscle substrate metabolism",332,"WP4030",6,0.33,0.5,0.5,7.99040804992212e-20,7.99040804992212e-20 "WP334","GPCRs, Class B Secretin-like",210,"WP334",24,0.17,0.5,0.5,3.06579274689702e-21,1.60955895014834e-18 "WP1991","SRF and miRs in Smooth Muscle Differentiation and Proliferation",60,"WP1991",13,0.69,0.888888888888889,1,5.37258163429194e-24,1.16900918682e-14 "WP206","Fatty Acid Omega Oxidation",76,"WP206",15,0.33,0.6,0.8,2.94021006969881e-38,1.31928124608757e-14 "WP3299","let-7 inhibition of ES cell reprogramming",205,"WP3299",15,0.33,0.6,0.6,1.69191698398203e-15,1.74501293167954e-14 "WP2023","Cell Differentiation - Index expanded",66,"WP2023",50,0.22,0.727272727272727,0.727272727272727,4.7856489956754e-16,2.33586928012365e-14 "WP2029","Cell Differentiation - Index",67,"WP2029",42,0.14,0.833333333333333,0.833333333333333,4.7856489956754e-16,2.33586928012365e-14 "WP2366","Butyrate-induced histone acetylation",105,"WP2366",2,1,0.5,0.5,1.10524321914212e-13,1.10524321914212e-13 "WP3297","EV release from cardiac cells and their functional effects",203,"WP3297",9,0.44,0.75,0.75,3.05550468161626e-32,3.37870774082303e-13 "WP554","ACE Inhibitor Pathway",530,"WP554",17,0.65,0.545454545454545,0.545454545454545,3.79036700534385e-25,5.54255202240522e-13 "WP4284","Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer",385,"WP4284",5,0.4,0.5,0.5,2.90591396510707e-11,2.90591396510707e-11 "WP2361","Gastric Cancer Network 1",103,"WP2361",29,0.76,0.727272727272727,0.727272727272727,3.61848623532521e-17,1.04514067941364e-10 "WP3944","Serotonin and anxiety-related events",309,"WP3944",13,0.46,0.666666666666667,0.666666666666667,1.45750470372243e-17,3.26510400891469e-09 "WP3947","Serotonin and anxiety",311,"WP3947",17,0.41,0.428571428571429,0.428571428571429,1.45750470372243e-17,3.26510400891469e-09 "WP1438","Influenza A virus infection",20,"WP1438",2,0.5,1,1,1.28737203377495e-08,1.28737203377495e-08 "WP383","Striated Muscle Contraction Pathway",265,"WP383",38,0.61,0.565217391304348,0.652173913043478,1.03667354058147e-21,1.30607861950122e-08 "WP2542","Sulindac Metabolic Pathway",133,"WP2542",5,0.8,0.5,0.75,4.35964063989166e-11,2.5564111779557e-08 "WP4222","Phosphodiesterases in neuronal function",366,"WP4222",55,0.56,0.419354838709677,0.483870967741935,1.11151548949677e-22,3.51064709129753e-08 "WP2943","Hypoxia-mediated EMT and Stemness",191,"WP2943",2,1,0.5,0.5,1.87433487284931e-07,1.87433487284931e-07 "WP2874","Liver X Receptor Pathway",175,"WP2874",10,0.5,0.4,0.4,9.83107916736652e-08,2.35055233649832e-07 "WP466","DNA Replication",480,"WP466",42,0.98,0.634146341463415,0.75609756097561,3.91911842678923e-14,4.20885218710584e-07 "WP545","Complement Activation",528,"WP545",22,0.68,0.466666666666667,0.466666666666667,3.75341311013175e-54,6.35126956702113e-07 "WP4240","Regulation of sister chromatid separation at the metaphase-anaphase transition",374,"WP4240",16,0.94,0.533333333333333,0.533333333333333,4.41152154021936e-12,6.65380602412947e-07 "WP4300","Extracellular vesicles in the crosstalk of cardiac cells",395,"WP4300",28,0.61,0.411764705882353,0.588235294117647,1.55030261832076e-25,8.80494600850642e-07 "WP531","DNA Mismatch Repair",525,"WP531",22,0.95,0.523809523809524,0.571428571428571,3.57124737003596e-13,1.25145166671192e-06 "WP4589","Major receptors targeted by epinephrine and norepinephrine",471,"WP4589",15,0.73,0.636363636363636,0.636363636363636,1.11151548949677e-22,2.66815064645758e-06 "WP4760","PKC-gamma calcium signaling pathway in ataxia",508,"WP4760",22,0.55,0.416666666666667,0.583333333333333,6.52294438984146e-17,2.70719651941471e-06 "WP4191","Caloric restriction and aging",354,"WP4191",8,1,0.375,0.375,2.9447393377517e-11,3.80469322236512e-06 "WP2446","Retinoblastoma Gene in Cancer",117,"WP2446",88,0.98,0.546511627906977,0.593023255813954,1.96366351804733e-14,4.24785596200959e-06 "WP1992","Genes targeted by miRNAs in adipocytes",61,"WP1992",19,0.53,0.5,0.5,2.33586928012365e-14,8.49856030430427e-06 "WP4337","ncRNAs involved in STAT3 signaling in hepatocellular carcinoma",406,"WP4337",17,0.76,0.538461538461538,0.615384615384615,1.55030261832076e-25,9.36831691097847e-06 "WP2645","Heroin metabolism",145,"WP2645",3,0.67,0.5,1,1.87627142351219e-05,1.87627142351219e-05 "WP2826","Cocaine metabolism",158,"WP2826",4,0.5,0.5,1,1.87627142351219e-05,1.87627142351219e-05 "WP1602","Nicotine Activity on Dopaminergic Neurons",40,"WP1602",22,0.5,0.636363636363636,0.818181818181818,2.50026382158374e-16,2.24952453555091e-05 "WP4545","Oxysterols derived from cholesterol",452,"WP4545",18,0.56,0.6,0.6,1.46780086933461e-09,2.36116814219851e-05 "WP45","G1 to S cell cycle control",430,"WP45",64,0.95,0.491803278688525,0.573770491803279,3.91911842678923e-14,2.89588011644963e-05 "WP1495","Glycine Metabolism",24,"WP1495",4,0.75,0.666666666666667,0.666666666666667,7.32732034249336e-10,2.91348117795513e-05 "WP2879","Farnesoid X Receptor Pathway",180,"WP2879",19,0.37,0.428571428571429,0.428571428571429,1.03671457774015e-11,0.000129931976156264 "WP34","Ovarian Infertility Genes",211,"WP34",32,0.53,0.411764705882353,0.411764705882353,8.1728342950092e-20,0.000152471085336278 "WP516","Hypertrophy Model",519,"WP516",20,0.75,0.466666666666667,0.533333333333333,1.73723649603814e-29,0.000166791537749366 "WP247","Small Ligand GPCRs",121,"WP247",19,0.53,0.6,0.8,3.77273931182897e-18,0.000182717661150266 "WP2363","Gastric Cancer Network 2",104,"WP2363",33,0.88,0.448275862068966,0.448275862068966,1.12863099668653e-15,0.000185246692246443 "WP170","Nuclear Receptors",44,"WP170",39,0.74,0.413793103448276,0.413793103448276,5.53853655041636e-45,0.000204208460415242 "WP3996","Ethanol effects on histone modifications",325,"WP3996",31,0.9,0.428571428571429,0.5,2.94021006969881e-38,0.000238758692258098 "WP4400","FABP4 in ovarian cancer",417,"WP4400",2,0.5,1,1,0.000245357066905715,0.000245357066905715 "WP58","Monoamine GPCRs",534,"WP58",33,0.15,0.6,0.6,2.66815064645758e-06,0.000266280491622695 "WP3679","Cell-type Dependent Selectivity of CCK2R Signaling",261,"WP3679",13,0.69,0.444444444444444,0.555555555555556,6.52294438984146e-17,0.000315427333264674 "WP2338","miRNA Biogenesis",99,"WP2338",8,0.75,0.5,0.5,5.52094234656009e-11,0.000633704399420972 "WP1455","Serotonin Transporter Activity",22,"WP1455",11,0.73,0.375,0.5,5.50097841431123e-07,0.000698192443745329 "WP4016","DNA IR-damage and cellular response via ATR",329,"WP4016",83,0.9,0.413333333333333,0.466666666666667,3.1984443894539e-16,0.000704575375419051 "WP179","Cell Cycle",48,"WP179",122,0.94,0.434782608695652,0.48695652173913,3.91911842678923e-14,0.000860192369254168 "WP2848","Differentiation Pathway",162,"WP2848",48,0.54,0.461538461538462,0.538461538461538,1.55030261832076e-25,0.000900218402911242 "WP2815","Mammary gland development pathway - Involution (Stage 4 of 4)",155,"WP2815",10,1,0.5,0.7,3.47598200773578e-10,0.000979886474579196 "WP322","Osteoblast Signaling",199,"WP322",14,0.5,0.428571428571429,0.428571428571429,1.60955895014834e-18,0.00122105800992755 "WP4583","Biomarkers for urea cycle disorders",467,"WP4583",12,0.67,0.375,0.375,1.05891161032475e-42,0.00125836568297114 "WP3893","Development and heterogeneity of the ILC family",289,"WP3893",32,0.56,0.5,0.555555555555556,1.55030261832076e-25,0.00137922281926359 "WP2406","Cardiac Progenitor Differentiation",112,"WP2406",53,0.57,0.466666666666667,0.5,5.00019440781505e-25,0.0019450999028179 "WP558","Complement and Coagulation Cascades",531,"WP558",59,0.66,0.41025641025641,0.487179487179487,3.75341311013175e-54,0.00204133415581446 "WP2516","ATM Signaling Pathway",127,"WP2516",40,0.92,0.405405405405405,0.459459459459459,6.96540853859659e-18,0.00226170199642674 "WP3876","BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation",282,"WP3876",13,0.85,0.454545454545455,0.454545454545455,1.1219536394885e-16,0.00287452439577986 "WP1545","miRNAs involved in DNA damage response",33,"WP1545",50,0.28,0.357142857142857,0.428571428571429,1.33825325438479e-13,0.00291300857028192 "WP3591","Sleep regulation",223,"WP3591",38,0.34,0.461538461538462,0.538461538461538,1.55030261832076e-25,0.00298637777295038 "WP2855","Dopaminergic Neurogenesis",166,"WP2855",30,0.33,0.4,0.6,8.1921343985721e-23,0.00300186445388684 "WP497","Urea cycle and metabolism of amino groups",515,"WP497",21,0.76,0.375,0.4375,1.21134935033961e-14,0.00350987947486594 "WP3407","FTO Obesity Variant Mechanism",212,"WP3407",8,0.88,0.428571428571429,0.428571428571429,2.9447393377517e-11,0.00376777148807062 "WP289","Myometrial Relaxation and Contraction Pathways",186,"WP289",158,0.76,0.391666666666667,0.466666666666667,4.72920713559152e-27,0.00465022180500277 "WP1530","miRNA Regulation of DNA Damage Response",27,"WP1530",93,0.69,0.375,0.453125,2.50026382158374e-16,0.00482551043459127 "WP4149","White fat cell differentiation",344,"WP4149",33,0.91,0.4,0.433333333333333,3.05550468161626e-32,0.00497520122591071 "WP2814","Mammary gland development pathway - Puberty (Stage 2 of 4)",154,"WP2814",13,0.92,0.5,0.5,8.1728342950092e-20,0.00569300599773054 "WP1603","Nicotine Activity on Chromaffin Cells",41,"WP1603",4,0.25,1,1,0.00581825930604642,0.00581825930604642 "WP4698","Vitamin D-sensitive calcium signaling in depression",486,"WP4698",41,0.54,0.363636363636364,0.5,6.52294438984146e-17,0.00581825930604642 "WP1971","Integrated Cancer Pathway",56,"WP1971",46,0.93,0.372093023255814,0.418604651162791,1.47590569356761e-12,0.00623426422936051 "WP4224","Purine metabolism and related disorders",368,"WP4224",22,0.86,0.368421052631579,0.421052631578947,3.39506009152496e-24,0.00660624701596271 "WP4259","Disorders of Folate Metabolism and Transport",379,"WP4259",13,0.85,0.454545454545455,0.454545454545455,7.32732034249336e-10,0.00660624701596271 "WP1601","Fluoropyrimidine Activity",39,"WP1601",34,0.82,0.392857142857143,0.5,7.38854762906026e-09,0.00668550277003425 "WP2806","Human Complement System",152,"WP2806",99,0.64,0.349206349206349,0.428571428571429,3.75341311013175e-54,0.00703640980157322 "WP707","DNA Damage Response",557,"WP707",69,0.9,0.370967741935484,0.451612903225806,2.50026382158374e-16,0.00934439177317729 "WP2895","Differentiation of white and brown adipocyte ",187,"WP2895",25,0.72,0.388888888888889,0.388888888888889,4.791051754563e-15,0.00971361957709086 "WP1995","Effects of Nitric Oxide",62,"WP1995",8,0.5,0.5,0.75,3.39506009152496e-24,0.0112147264561884 "WP136","Phase I biotransformations, non P450",10,"WP136",8,0.62,0.4,0.6,1.87627142351219e-05,0.0123569322150726 "WP536","Calcium Regulation in the Cardiac Cell",527,"WP536",152,0.7,0.355140186915888,0.429906542056075,7.92756655687513e-25,0.0169432049684982 "WP35","G Protein Signaling Pathways",216,"WP35",97,0.78,0.355263157894737,0.434210526315789,1.11151548949677e-22,0.0169866528793556 "WP241","One Carbon Metabolism",113,"WP241",31,0.81,0.4,0.48,7.32732034249336e-10,0.0170103318686093 "WP4571","Urea cycle and related diseases",464,"WP4571",9,0.67,0.5,0.5,6.0595781921859e-07,0.020635406510022 "WP4752","Base Excision Repair",503,"WP4752",31,0.97,0.4,0.466666666666667,3.57124737003596e-13,0.0220340720140378 "WP4720","Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway",491,"WP4720",9,0.44,0.5,0.5,4.43345799464762e-09,0.0230432320025256 "WP474","Endochondral Ossification",498,"WP474",65,0.83,0.351851851851852,0.462962962962963,4.81536487673321e-20,0.0246820506324245 "WP3875","ATR Signaling",281,"WP3875",9,0.89,0.375,0.375,4.60260415203756e-08,0.0248929712443472 "WP3959","DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM",314,"WP3959",55,0.95,0.346153846153846,0.423076923076923,2.50026382158374e-16,0.0248929712443472 "WP4560","MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement",458,"WP4560",18,0.94,0.411764705882353,0.470588235294118,6.52294438984146e-17,0.0254612754912739 "WP2525","Trans-sulfuration and one carbon metabolism",128,"WP2525",32,0.88,0.357142857142857,0.464285714285714,7.32732034249336e-10,0.0321645449138761 "WP98","Prostaglandin Synthesis and Regulation",568,"WP98",45,0.82,0.378378378378378,0.459459459459459,2.17394413943821e-22,0.0332806226599994 "WP4304","Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS",397,"WP4304",31,0.52,0.375,0.375,7.83386153710323e-26,0.0344632354643189 "WP3599","Transcription factor regulation in adipogenesis",228,"WP3599",22,0.86,0.368421052631579,0.368421052631579,1.55030261832076e-25,0.0362388400314306 "WP1604","Codeine and Morphine Metabolism",42,"WP1604",15,0.27,0.5,0.5,6.49286728094462e-06,0.0372370714105519 "WP236","Adipogenesis",102,"WP236",131,0.79,0.346153846153846,0.413461538461538,3.75341311013175e-54,0.0373548404617312 "WP4661","Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension)",481,"WP4661",6,0.33,0.5,0.5,0.0431468886224066,0.0431468886224066 "WP3585","Cytosine methylation",222,"WP3585",9,0.89,0.375,0.5,7.49087453817701e-07,0.046146524101977 "WP3872","Regulation of Apoptosis by Parathyroid Hormone-related Protein",279,"WP3872",22,0.91,0.35,0.45,1.28737203377495e-08,0.0485074090657223 "WP4399","MicroRNA network associated with chronic lymphocytic leukemia",416,"WP4399",7,0.57,0.5,0.5,1.28737203377495e-08,0.0485074090657223 "WP53","ID signaling pathway",523,"WP53",16,0.81,0.307692307692308,0.384615384615385,1.33825325438479e-13,0.0542788662751285 "WP734","Serotonin Receptor 4/6/7 and NR3C Signaling",564,"WP734",19,0.84,0.3125,0.375,1.69191698398203e-15,0.0542788662751285 "WP2881","Estrogen Receptor Pathway",182,"WP2881",13,0.77,0.3,0.4,2.58938282317479e-38,0.0594386193019534 "WP3963","Mevalonate pathway",315,"WP3963",7,1,0.285714285714286,0.428571428571429,0.00314781622146767,0.0618737980244723 "WP2197","Endothelin Pathways",81,"WP2197",34,0.68,0.304347826086957,0.391304347826087,4.72920713559152e-27,0.0668243064530906 "WP2355","Corticotropin-releasing hormone signaling pathway",100,"WP2355",93,0.78,0.328767123287671,0.410958904109589,5.53853655041636e-45,0.0668243064530906 "WP727","Monoamine Transport",561,"WP727",32,0.53,0.294117647058824,0.529411764705882,4.62070637396041e-12,0.0730490654877152 "WP167","Eicosanoid Synthesis",43,"WP167",27,0.67,0.333333333333333,0.388888888888889,2.17394413943821e-22,0.0735098081465718 "WP3624","Lung fibrosis",235,"WP3624",63,0.67,0.30952380952381,0.428571428571429,1.55030261832076e-25,0.080115977530217 "WP4584","Biomarkers for pyrimidine metabolism disorders",468,"WP4584",15,0.8,0.333333333333333,0.5,2.56816439701713e-12,0.0832724893457054 "WP4204","Tumor suppressor activity of SMARCB1",357,"WP4204",33,0.79,0.269230769230769,0.423076923076923,7.79200875278231e-09,0.0908144088489654 "WP4719","Eicosanoid metabolism via Cyclo Oxygenases (COX)",490,"WP4719",30,0.7,0.333333333333333,0.380952380952381,2.17394413943821e-22,0.0918721376616465 "WP3611","Photodynamic therapy-induced AP-1 survival signaling.",230,"WP3611",51,0.9,0.304347826086957,0.456521739130435,1.55030261832076e-25,0.093911573076689 "WP2011","SREBF and miR33 in cholesterol and lipid homeostasis",64,"WP2011",19,0.84,0.3125,0.4375,2.9447393377517e-11,0.103949453944605 "WP3892","Development of pulmonary dendritic cells and macrophage subsets",288,"WP3892",13,0.77,0.2,0.7,7.70437079680464e-06,0.111367348220358 "WP2431","Spinal Cord Injury",114,"WP2431",120,0.75,0.322222222222222,0.4,5.53853655041636e-45,0.114048118916392 "WP272","Blood Clotting Cascade",148,"WP272",23,0.52,0.333333333333333,0.5,1.05891161032475e-42,0.114803285411883 "WP117","GPCRs, Other",5,"WP117",94,0.23,0.318181818181818,0.363636363636364,3.77273931182897e-18,0.120172770046016 "WP3596","miR-517 relationship with ARCN1 and USP1",227,"WP3596",5,1,0.2,0.4,7.70437079680464e-06,0.123137649892892 "WP3672","LncRNA-mediated mechanisms of therapeutic resistance",257,"WP3672",12,0.58,0.285714285714286,0.428571428571429,1.61117377276123e-06,0.123137649892892 "WP3995","Prion disease pathway",324,"WP3995",37,0.84,0.258064516129032,0.419354838709677,1.42295577093001e-17,0.148008766451471 "WP4147","PTF1A related regulatory pathway",342,"WP4147",11,0.45,0.2,0.4,0.000808563677475246,0.156029921726251 "WP2849","Hematopoietic Stem Cell Differentiation",163,"WP2849",63,0.68,0.325581395348837,0.395348837209302,1.4645909158934e-29,0.156167098725433 "WP3958","GPR40 Pathway",313,"WP3958",16,0.81,0.307692307692308,0.538461538461538,1.06179313771239e-06,0.156624702837221 "WP4249","Hedgehog Signaling Pathway",376,"WP4249",44,0.77,0.264705882352941,0.411764705882353,6.45939424963396e-09,0.171056939850016 "WP2846","Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation",161,"WP2846",3,0.33,0,1,0.191601747736878,0.191601747736878 "WP3408","Evolocumab Mechanism",213,"WP3408",3,0.33,0,1,0.191601747736878,0.191601747736878 "WP2118","Arrhythmogenic Right Ventricular Cardiomyopathy",80,"WP2118",76,0.74,0.303571428571429,0.410714285714286,6.58880500842654e-23,0.19520059624092 "WP3640","Imatinib and Chronic Myeloid Leukemia",243,"WP3640",21,0.95,0.3,0.4,3.36912948711107e-08,0.202640916207215 "WP2007","Iron metabolism in placenta",63,"WP2007",12,0.67,0.25,0.375,0.000425327317103322,0.20667484530917 "WP129","Matrix Metalloproteinases",8,"WP129",30,0.73,0.272727272727273,0.409090909090909,1.66846236358396e-28,0.217106999492912 "WP4754","IL-18 signaling pathway",505,"WP4754",279,0.8,0.265765765765766,0.373873873873874,5.53853655041636e-45,0.224063872360977 "WP3301","MFAP5-mediated ovarian cancer cell motility and invasiveness",207,"WP3301",13,1,0.230769230769231,0.384615384615385,7.1834548445351e-10,0.236415904297976 "WP704","Methylation Pathways",555,"WP704",10,0.7,0.142857142857143,0.428571428571429,1.10795143781028e-12,0.241165469354808 "WP3930","EDA Signalling in Hair Follicle Development",297,"WP3930",14,0.64,0.222222222222222,0.555555555555556,6.78928901696758e-07,0.24293224118149 "WP3967","miR-509-3p alteration of YAP1/ECM axis",317,"WP3967",19,0.89,0.235294117647059,0.352941176470588,3.92971708713555e-06,0.246081089028509 "WP2858","Ectoderm Differentiation",168,"WP2858",144,0.78,0.285714285714286,0.366071428571429,6.10911950894992e-26,0.251410075884791 "WP428","Wnt Signaling",384,"WP428",118,0.79,0.301075268817204,0.365591397849462,5.00019440781505e-25,0.251410075884791 "WP1434","Osteopontin Signaling",19,"WP1434",13,1,0.230769230769231,0.461538461538462,1.51229007711679e-12,0.257536764433672 "WP176","Folate Metabolism",46,"WP176",73,0.6,0.295454545454545,0.409090909090909,1.55030261832076e-25,0.257536764433672 "WP28","Selenium Metabolism and Selenoproteins",150,"WP28",46,0.61,0.25,0.392857142857143,2.4987918295779e-23,0.257536764433672 "WP2840","Hair Follicle Development: Cytodifferentiation (Part 3 of 3)",160,"WP2840",88,0.64,0.267857142857143,0.375,1.4645909158934e-29,0.257536764433672 "WP3617","Photodynamic therapy-induced NF-kB survival signaling",234,"WP3617",35,0.86,0.233333333333333,0.4,1.55030261832076e-25,0.257536764433672 "WP2059","Alzheimers Disease",75,"WP2059",150,0.46,0.260869565217391,0.36231884057971,6.52294438984146e-17,0.264407820025205 "WP4658","Small cell lung cancer",478,"WP4658",98,0.91,0.269662921348315,0.359550561797753,1.33825325438479e-13,0.266714097046007 "WP237","Glucocorticoid and Mineralcorticoid Metabolism",107,"WP237",8,0.25,0,0.5,0.273007477872406,0.273007477872406 "WP3287","Overview of nanoparticle effects",202,"WP3287",19,0.79,0.266666666666667,0.4,1.55030261832076e-25,0.292450502904674 "WP4586","Metabolism of alpha-linolenic acid",470,"WP4586",7,0.86,0.166666666666667,0.5,0.0386740237126384,0.296626199889639 "WP3580","Methionine De Novo and Salvage Pathway",220,"WP3580",22,0.86,0.210526315789474,0.368421052631579,4.35964063989166e-11,0.301026666733762 "WP4481","Resistin as a regulator of inflammation",422,"WP4481",33,0.85,0.25,0.357142857142857,1.55030261832076e-25,0.310639518319511 "WP3595","mir-124 predicted interactions with cell cycle and differentiation ",226,"WP3595",7,0.86,0.333333333333333,0.5,1.28871879017951e-06,0.311537001183337 "WP4225","Pyrimidine metabolism and related diseases",369,"WP4225",17,0.71,0.25,0.416666666666667,1.65319775729734e-07,0.312696646387934 "WP24","Peptide GPCRs",111,"WP24",75,0.28,0.285714285714286,0.428571428571429,1.91116166189054e-21,0.317365436064072 "WP4336","ncRNAs involved in Wnt signaling in hepatocellular carcinoma",405,"WP4336",91,0.76,0.289855072463768,0.36231884057971,5.00019440781505e-25,0.320170838547363 "WP4462","Platelet-mediated interactions with vascular and circulating cells",418,"WP4462",17,0.88,0.266666666666667,0.4,1.28837373141904e-08,0.341095356415239 "WP4493","Cells and Molecules involved in local acute inflammatory response ",426,"WP4493",17,0.76,0.307692307692308,0.384615384615385,1.55030261832076e-25,0.341095356415239 "WP3670","Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway",256,"WP3670",21,0.81,0.176470588235294,0.352941176470588,2.45932835171728e-12,0.357129134137342 "WP4538","Regulatory circuits of the STAT3 signaling pathway",447,"WP4538",79,0.85,0.26865671641791,0.343283582089552,1.91116166189054e-21,0.363878327573958 "WP229","Irinotecan Pathway",90,"WP229",13,0.54,0.285714285714286,0.428571428571429,1.87627142351219e-05,0.372595026103777 "WP4172","PI3K-Akt Signaling Pathway",350,"WP4172",345,0.73,0.281746031746032,0.361111111111111,1.96319556679318e-26,0.389653492019368 "WP3584","MECP2 and Associated Rett Syndrome",221,"WP3584",71,0.72,0.274509803921569,0.352941176470588,2.08918249834541e-15,0.389709140526829 "WP530","Cytokines and Inflammatory Response",524,"WP530",27,0.52,0.214285714285714,0.357142857142857,1.55030261832076e-25,0.394616722859002 "WP3888","VEGFA-VEGFR2 Signaling Pathway",286,"WP3888",438,0.92,0.255583126550869,0.359801488833747,5.53853655041636e-45,0.415827475604265 "WP4537","Hippo-Yap signaling pathway",446,"WP4537",23,1,0.130434782608696,0.347826086956522,1.54778757247964e-06,0.425582638865984 "WP4673","Genes involved in male infertility",483,"WP4673",155,0.55,0.223529411764706,0.352941176470588,8.15687289296435e-21,0.434708802034794 "WP4258","LncRNA involvement in canonical Wnt signaling and colorectal cancer",378,"WP4258",104,0.73,0.276315789473684,0.342105263157895,5.00019440781505e-25,0.442641490692933 "WP1528","Physiological and Pathological Hypertrophy of the Heart",26,"WP1528",25,0.96,0.291666666666667,0.375,1.45750470372243e-17,0.443468145964458 "WP1539","Angiogenesis",30,"WP1539",24,1,0.25,0.375,2.08918249834541e-15,0.443468145964458 "WP2586","Aryl Hydrocarbon Receptor Netpath",136,"WP2586",48,0.83,0.225,0.35,1.44400359316927e-08,0.452666162731714 "WP2865","IL1 and megakaryocytes in obesity",171,"WP2865",25,0.84,0.238095238095238,0.380952380952381,5.19525794232389e-10,0.452666162731714 "WP384","Apoptosis Modulation by HSP70",266,"WP384",19,0.95,0.166666666666667,0.388888888888889,6.96540853859659e-18,0.452666162731714 "WP706","Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways",556,"WP706",164,0.61,0.31,0.35,7.75341732836066e-26,0.452666162731714 "WP1742","TP53 Network",45,"WP1742",20,0.9,0.222222222222222,0.388888888888889,1.28737203377495e-08,0.467750156194828 "WP2507","Nanomaterial induced apoptosis",124,"WP2507",20,0.95,0.105263157894737,0.368421052631579,1.28737203377495e-08,0.467750156194828 "WP2267","Synaptic Vesicle Pathway",86,"WP2267",52,0.6,0.258064516129032,0.354838709677419,6.97840140254166e-30,0.492132771972666 "WP2038","Regulation of Microtubule Cytoskeleton",73,"WP2038",49,0.86,0.285714285714286,0.357142857142857,5.70447887867626e-23,0.498108980109511 "WP3594","Circadian rhythm related genes",225,"WP3594",207,0.67,0.289855072463768,0.340579710144928,1.86144948015588e-42,0.502912219194388 "WP186","Homologous recombination",51,"WP186",13,0.92,0.333333333333333,0.333333333333333,3.57124737003596e-13,0.503680038828547 "WP4299","Lamin A-processing pathway",392,"WP4299",3,1,0.333333333333333,0.333333333333333,0.0375633720082355,0.525565992204199 "WP26","Signal Transduction of S1P Receptor",139,"WP26",26,0.92,0.208333333333333,0.333333333333333,1.36035451223937e-09,0.537154575485495 "WP3932","Focal Adhesion-PI3K-Akt-mTOR-signaling pathway",299,"WP3932",309,0.79,0.246913580246914,0.337448559670782,1.96319556679318e-26,0.55485006897197 "WP3529","Zinc homeostasis",218,"WP3529",37,0.65,0.208333333333333,0.333333333333333,1.09751947262418e-13,0.559735276252208 "WP3613","Photodynamic therapy-induced unfolded protein response",232,"WP3613",29,0.83,0.25,0.333333333333333,1.63572753987345e-09,0.592395677119481 "WP455","GPCRs, Class A Rhodopsin-like",454,"WP455",258,0.22,0.241379310344828,0.327586206896552,1.91116166189054e-21,0.594474156958518 "WP314","Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation",198,"WP314",44,0.91,0.175,0.325,1.28737203377495e-08,0.596740036001061 "WP4321","Thermogenesis",401,"WP4321",108,0.83,0.266666666666667,0.333333333333333,2.44977316588364e-24,0.602303776230422 "WP1533","Vitamin B12 Metabolism",29,"WP1533",53,0.57,0.2,0.333333333333333,1.55030261832076e-25,0.625924461178548 "WP254","Apoptosis",132,"WP254",86,0.93,0.225,0.3375,6.96540853859659e-18,0.630454225897172 "WP2817","Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)",157,"WP2817",33,0.76,0.32,0.32,8.1728342950092e-20,0.631033926043019 "WP4286","Genotoxicity pathway",386,"WP4286",63,0.78,0.244897959183673,0.326530612244898,6.52294438984146e-17,0.633739231633592 "WP4228","Vitamin B6-dependent and responsive disorders",370,"WP4228",5,0.8,0.25,0.25,0.00334024416831868,0.635216999029685 "WP306","Focal Adhesion",195,"WP306",202,0.86,0.248554913294798,0.323699421965318,1.96319556679318e-26,0.661870634611933 "WP3941","Oxidative Damage",306,"WP3941",41,0.9,0.243243243243243,0.324324324324324,1.28737203377495e-08,0.699923750757195 "WP561","Heme Biosynthesis",533,"WP561",9,0.89,0.25,0.25,6.5794345319789e-05,0.701076830955824 "WP4541","Hippo-Merlin Signaling Dysregulation",450,"WP4541",123,0.77,0.221052631578947,0.315789473684211,5.28168194977512e-22,0.723397294815617 "WP2064","Neural Crest Differentiation",77,"WP2064",102,0.63,0.25,0.328125,1.94200095136959e-19,0.727478052387628 "WP3678","Amplification and Expansion of Oncogenic Pathways as Metastatic Traits",260,"WP3678",17,1,0.117647058823529,0.294117647058824,6.04285700943382e-06,0.727478052387628 "WP3935","Leptin Insulin Overlap",302,"WP3935",17,0.82,0.285714285714286,0.285714285714286,9.45573250233619e-09,0.741018446305419 "WP1772","Apoptosis Modulation and Signaling",47,"WP1772",93,0.85,0.189873417721519,0.316455696202532,6.96540853859659e-18,0.744856843612274 "WP2877","Vitamin D Receptor Pathway",178,"WP2877",186,0.63,0.271186440677966,0.322033898305085,7.99040804992212e-20,0.818823949216948 "WP1591","Heart Development",37,"WP1591",46,0.65,0.266666666666667,0.3,1.16900918682e-14,0.842767793418932 "WP4357","NRF2-ARE regulation",410,"WP4357",23,0.96,0.227272727272727,0.318181818181818,6.33815645362995e-08,0.87065004588454 "WP2882","Nuclear Receptors Meta-Pathway",183,"WP2882",322,0.69,0.238738738738739,0.315315315315315,2.58938282317479e-38,0.88225486075262 "WP2032","Human Thyroid Stimulating Hormone (TSH) signaling pathway",68,"WP2032",68,0.91,0.274193548387097,0.32258064516129,8.47368187861688e-16,0.884931793800649 "WP3998","Prader-Willi and Angelman Syndrome",326,"WP3998",66,0.45,0.333333333333333,0.333333333333333,2.9765880724211e-12,0.892842095899067 "WP2369","Histone Modifications",106,"WP2369",70,0.43,0.166666666666667,0.3,4.29629046913145e-07,0.898693967045816 "WP4540","Pathways Regulating Hippo Signaling",449,"WP4540",99,0.81,0.225,0.325,1.45750470372243e-17,0.900720485325998 "WP4022","Pyrimidine metabolism",331,"WP4022",87,0.91,0.253164556962025,0.329113924050633,3.57124737003596e-13,0.90295173404126 "WP4484","Control of immune tolerance by vasoactive intestinal peptide",425,"WP4484",13,0.31,0,0.25,0.189083662421517,0.90837549057179 "WP3527","Preimplantation Embryo",217,"WP3527",60,0.52,0.193548387096774,0.290322580645161,1.4645909158934e-29,0.920619031124591 "WP408","Oxidative Stress",335,"WP408",34,0.85,0.206896551724138,0.310344827586207,2.4987918295779e-23,0.926181011736354 "WP4297","Thiamine metabolic pathways",390,"WP4297",9,0.89,0,0.25,0.171095325811961,0.927438681383965 "WP1984","Integrated Breast Cancer Pathway",59,"WP1984",155,0.92,0.27972027972028,0.314685314685315,3.61848623532521e-17,0.929014479457768 "WP3972","PDGFR-beta pathway",320,"WP3972",29,1,0.241379310344828,0.275862068965517,1.45750470372243e-17,0.936983896443534 "WP15","Selenium Micronutrient Network",25,"WP15",92,0.54,0.2,0.32,1.55030261832076e-25,0.94158668008034 "WP1423","Ganglio Sphingolipid Metabolism",14,"WP1423",13,0.62,0.25,0.25,4.87851969602103e-17,0.954898577153562 "WP4298","Viral Acute Myocarditis",391,"WP4298",85,0.82,0.228571428571429,0.314285714285714,1.55030261832076e-25,0.960973679911299 "WP2374","Oncostatin M Signaling Pathway",109,"WP2374",66,0.97,0.25,0.3125,1.45750470372243e-17,0.962619223865447 "WP3850","Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling",270,"WP3850",31,0.94,0.241379310344828,0.310344827586207,2.9447393377517e-11,0.979681670178472 "WP3657","Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex",250,"WP3657",22,0.86,0.315789473684211,0.315789473684211,1.28737203377495e-08,0.990973876560315 "WP465","Tryptophan metabolism",474,"WP465",42,0.64,0.259259259259259,0.333333333333333,1.2733947666864e-33,0.991085216247916 "WP1541","Energy Metabolism",31,"WP1541",48,0.88,0.30952380952381,0.333333333333333,4.7856489956754e-16,0.991457884585696 "WP4148","Splicing factor NOVA regulated synaptic proteins",343,"WP4148",42,0.74,0.258064516129032,0.32258064516129,8.59680057967434e-17,0.99308777325874 "WP2380","Brain-Derived Neurotrophic Factor (BDNF) signaling pathway",110,"WP2380",144,0.85,0.227642276422764,0.284552845528455,2.46076597989882e-17,0.993357395961217 "WP183","Proteasome Degradation",49,"WP183",64,0.91,0.189655172413793,0.258620689655172,0.000102727400071607,0.993739319892961 "WP3942","PPAR signaling pathway",307,"WP3942",67,0.67,0.244444444444444,0.266666666666667,4.45382103461115e-22,0.993946338790036 "WP4341","Non-genomic actions of 1,25 dihydroxyvitamin D3",407,"WP4341",71,0.82,0.224137931034483,0.310344827586207,1.55030261832076e-25,0.997223465039722 "WP2036","TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway",71,"WP2036",42,0.95,0.2,0.3,1.55030261832076e-25,0.998306181536745 "WP262","EBV LMP1 signaling",140,"WP262",24,0.83,0.2,0.3,1.31802719833037e-09,0.998306181536745 "WP4008","NO/cGMP/PKG mediated Neuroprotection",328,"WP4008",48,0.52,0.24,0.32,3.3920313877351e-19,0.998306181536745 "WP4480","Role of Altered Glycolysation of MUC1 in Tumour Microenvironment",421,"WP4480",9,0.89,0.125,0.25,1.55030261832076e-25,0.998306181536745 "WP411","mRNA Processing",337,"WP411",133,0.92,0.204918032786885,0.286885245901639,7.40715848733595e-20,0.999556795185293 "WP4290","Metabolic reprogramming in colon cancer",388,"WP4290",44,0.89,0.230769230769231,0.282051282051282,1.21134935033961e-14,0.999559974562214 "WP2583","T-Cell Receptor and Co-stimulatory Signaling",135,"WP2583",29,0.93,0.0740740740740741,0.185185185185185,0.0020390189701393,0.999564052655054 "WP2113","Type III interferon signaling",79,"WP2113",10,0.6,0.333333333333333,0.333333333333333,0.000341914298724229,0.999577405939352 "WP2203","Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway",83,"WP2203",47,0.96,0.2,0.266666666666667,1.55030261832076e-25,0.999581638329153 "WP3929","Chemokine signaling pathway",296,"WP3929",165,0.75,0.233870967741935,0.306451612903226,1.11151548949677e-22,0.999581638329153 "WP2878","PPAR Alpha Pathway",179,"WP2878",26,0.62,0.3125,0.3125,2.35000378034819e-10,0.999593630002801 "WP4211","Transcriptional cascade regulating adipogenesis",361,"WP4211",13,1,0.307692307692308,0.307692307692308,3.05550468161626e-32,0.999597380647255 "WP395","IL-4 Signaling Pathway",312,"WP395",55,0.96,0.169811320754717,0.264150943396226,1.21006371795151e-15,0.999598637344068 "WP4756","Renin Angiotensin Aldosterone System (RAAS)",506,"WP4756",44,0.64,0.214285714285714,0.285714285714286,3.79036700534385e-25,0.999600844420397 "WP2037","Prolactin Signaling Pathway",72,"WP2037",76,0.96,0.164383561643836,0.246575342465753,1.21006371795151e-15,0.999622158178795 "WP3646","Hepatitis C and Hepatocellular Carcinoma",246,"WP3646",50,0.88,0.25,0.340909090909091,1.55030261832076e-25,0.999661972130556 "WP3414","Initiation of transcription and translation elongation at the HIV-1 LTR",215,"WP3414",37,0.73,0.259259259259259,0.296296296296296,1.30274002920557e-12,0.999679395222021 "WP1422","Sphingolipid pathway",13,"WP1422",30,0.8,0.166666666666667,0.25,3.69949076638916e-07,0.999680873684117 "WP4142","Metabolism of Spingolipids in ER and Golgi apparatus",340,"WP4142",20,0.75,0.2,0.2,1.78651764239784e-05,0.999680873684117 "WP4725","Sphingolipid Metabolism (general overview)",496,"WP4725",24,0.83,0.2,0.25,1.3073328528498e-06,0.999680873684117 "WP2359","Parkin-Ubiquitin Proteasomal System pathway",101,"WP2359",70,0.84,0.152542372881356,0.23728813559322,1.33825325438479e-13,0.999692096078023 "WP2911","miRNA targets in ECM and membrane receptors",188,"WP2911",43,0.51,0.227272727272727,0.272727272727273,1.96319556679318e-26,0.999694369321929 "WP4262","Breast cancer pathway",380,"WP4262",157,0.77,0.214876033057851,0.28099173553719,8.1728342950092e-20,0.999736194038243 "WP2636","Common Pathways Underlying Drug Addiction",141,"WP2636",42,0.57,0.166666666666667,0.25,8.80436312071741e-23,0.999745706039956 "WP2828","Bladder Cancer",159,"WP2828",41,0.93,0.184210526315789,0.289473684210526,2.88662493064661e-07,0.999745706039956 "WP3612","Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling",231,"WP3612",24,0.88,0.0952380952380952,0.238095238095238,1.21006371795151e-15,0.999752419955776 "WP4312","Rett syndrome causing genes",398,"WP4312",49,0.76,0.216216216216216,0.297297297297297,1.22943627951508e-14,0.999766525303437 "WP2533","Glycerophospholipid Biosynthetic Pathway",130,"WP2533",30,0.83,0.08,0.16,3.98592395806362e-10,0.999787685558907 "WP3940","One carbon metabolism and related pathways",305,"WP3940",54,0.72,0.230769230769231,0.256410256410256,2.86780567028817e-25,0.999787685558907 "WP4657","22q11.2 Deletion Syndrome",477,"WP4657",92,0.63,0.258620689655172,0.310344827586207,5.10653311534479e-29,0.999801314777508 "WP382","MAPK Signaling Pathway",264,"WP382",249,0.78,0.261538461538462,0.302564102564103,5.53853655041636e-45,0.999829075430104 "WP4666","Hepatitis B infection",482,"WP4666",154,0.84,0.2,0.276923076923077,1.55030261832076e-25,0.999846173141814 "WP107","Translation Factors",3,"WP107",54,0.87,0.234042553191489,0.276595744680851,8.52450711689985e-13,0.999852323093054 "WP1424","Globo Sphingolipid Metabolism",15,"WP1424",21,0.95,0.2,0.2,4.87851969602103e-17,0.999852323093054 "WP1584","Type II diabetes mellitus",35,"WP1584",22,0.64,0.142857142857143,0.142857142857143,7.99040804992212e-20,0.999852323093054 "WP2018","RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway",65,"WP2018",55,0.95,0.0961538461538462,0.192307692307692,1.21006371795151e-15,0.999852323093054 "WP231","TNF alpha Signaling Pathway",94,"WP231",94,0.94,0.204545454545455,0.284090909090909,1.55030261832076e-25,0.999852323093054 "WP2371","Parkinsons Disease Pathway",108,"WP2371",84,0.37,0.193548387096774,0.290322580645161,6.96540853859659e-18,0.999852323093054 "WP244","Alpha 6 Beta 4 signaling pathway",116,"WP244",35,0.94,0.121212121212121,0.181818181818182,2.61142544133486e-11,0.999852323093054 "WP2453","TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)",119,"WP2453",16,0.94,0.0666666666666667,0.0666666666666667,1.10524321914212e-13,0.999852323093054 "WP2456","HIF1A and PPARG regulation of glycolysis",120,"WP2456",8,0.75,0.166666666666667,0.166666666666667,0.00320215171958638,0.999852323093054 "WP2854","Gene regulatory network modelling somitogenesis ",165,"WP2854",11,0.55,0.166666666666667,0.166666666666667,0.0396104615656672,0.999852323093054 "WP2870","Extracellular vesicle-mediated signaling in recipient cells",173,"WP2870",30,0.9,0.185185185185185,0.222222222222222,1.47923810515956e-16,0.999852323093054 "WP3","Phytochemical activity on NRF2 transcriptional activation",193,"WP3",15,0.93,0.0714285714285714,0.214285714285714,0.00237947159212301,0.999852323093054 "WP3286","Copper homeostasis",201,"WP3286",54,0.87,0.234042553191489,0.297872340425532,3.71596808468601e-16,0.999852323093054 "WP3298","Melatonin metabolism and effects",204,"WP3298",42,0.62,0.269230769230769,0.307692307692308,1.86144948015588e-42,0.999852323093054 "WP3413","NOTCH1 regulation of human endothelial cell calcification",214,"WP3413",18,0.89,0.125,0.125,2.23804617426945e-12,0.999852323093054 "WP3601","Composition of Lipid Particles",229,"WP3601",10,0.4,0,0.25,0.191601747736878,0.999852323093054 "WP3633","Caffeine and Theobromine metabolism",239,"WP3633",4,0.25,0,0,0.999852323093054,0.999852323093054 "WP3664","Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds",253,"WP3664",18,0.89,0.1875,0.3125,8.33920870140507e-09,0.999852323093054 "WP3845","Canonical and Non-canonical Notch signaling",268,"WP3845",27,0.81,0.0909090909090909,0.181818181818182,0.000608063456248664,0.999852323093054 "WP3859","TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition",274,"WP3859",18,0.94,0.0588235294117647,0.0588235294117647,2.97846854097459e-06,0.999852323093054 "WP3931","ESC Pluripotency Pathways",298,"WP3931",119,0.7,0.265060240963855,0.289156626506024,1.04633266994318e-15,0.999852323093054 "WP3945","TYROBP Causal Network",310,"WP3945",63,0.9,0.12280701754386,0.175438596491228,1.51229007711679e-12,0.999852323093054 "WP3965","Lipid Metabolism Pathway",316,"WP3965",29,0.9,0.269230769230769,0.269230769230769,1.10524321914212e-13,0.999852323093054 "WP3982","miRNA regulation of p53 pathway in prostate cancer",322,"WP3982",34,0.68,0.0869565217391304,0.217391304347826,4.32292432502445e-07,0.999852323093054 "WP4153","Degradation pathway of sphingolipids, including diseases",346,"WP4153",10,0.8,0,0,0.999852323093054,0.999852323093054 "WP4156","Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases",348,"WP4156",2,1,0,0,0.999852323093054,0.999852323093054 "WP4159","GABA receptor Signaling",349,"WP4159",33,0.39,0.0769230769230769,0.0769230769230769,0.0013300266749614,0.999852323093054 "WP4220","Neurotransmitter Disorders",365,"WP4220",4,0.25,0,0,0.999852323093054,0.999852323093054 "WP43","Oxidation by Cytochrome P450",393,"WP43",63,0.48,0.133333333333333,0.166666666666667,7.53565262981462e-07,0.999852323093054 "WP4320","The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome",400,"WP4320",39,0.56,0.227272727272727,0.227272727272727,5.61788394294512e-16,0.999852323093054 "WP4342","Vitamins A and D - action mechanisms",408,"WP4342",3,1,0.333333333333333,0.333333333333333,1.20099662033474e-06,0.999852323093054 "WP437","EGF/EGFR Signaling Pathway",411,"WP437",164,0.95,0.206451612903226,0.232258064516129,1.4645909158934e-29,0.999852323093054 "WP4482","Vitamin D in inflammatory diseases",423,"WP4482",22,0.95,0.19047619047619,0.285714285714286,1.16949610776226e-27,0.999852323093054 "WP4483","Relationship between inflammation, COX-2 and EGFR",424,"WP4483",25,0.88,0.272727272727273,0.318181818181818,6.500496706318e-05,0.999852323093054 "WP4519","Cerebral Organic Acidurias, including diseases",435,"WP4519",7,1,0.285714285714286,0.285714285714286,1.97077141104003e-05,0.999852323093054 "WP4522","Metabolic pathway of LDL, HDL and TG, including diseases",437,"WP4522",17,0.53,0,0.222222222222222,0.0725218231021907,0.999852323093054 "WP4535","Envelope proteins and their potential roles in EDMD physiopathology",444,"WP4535",46,0.89,0.24390243902439,0.268292682926829,1.11151548949677e-22,0.999852323093054 "WP4549","Fragile X Syndrome ",453,"WP4549",123,0.76,0.172043010752688,0.21505376344086,6.52294438984146e-17,0.999852323093054 "WP4562","Canonical NF-KB pathway",460,"WP4562",8,1,0,0.125,0.452666162731714,0.999852323093054 "WP4585","Cancer immunotherapy by PD-1 blockade",469,"WP4585",24,0.88,0.0952380952380952,0.19047619047619,2.79548473355309e-05,0.999852323093054 "WP4724","Omega-9 FA synthesis",495,"WP4724",16,0.75,0.166666666666667,0.25,9.83107916736652e-08,0.999852323093054 "WP4758","Nephrotic syndrome",507,"WP4758",45,0.73,0.151515151515152,0.181818181818182,7.19331431961561e-10,0.999852323093054 "WP550","Biogenic Amine Synthesis",529,"WP550",16,0.19,0.333333333333333,0.333333333333333,0.0013300266749614,0.999852323093054 "WP100","Glutathione metabolism",1,"WP100",23,0.7,0.0625,0.0625,2.4987918295779e-23,0.999852323093054 "WP106","Alanine and aspartate metabolism",2,"WP106",12,0.58,0.142857142857143,0.142857142857143,0.0013300266749614,0.999852323093054 "WP111","Electron Transport Chain (OXPHOS system in mitochondria)",4,"WP111",106,0.66,0.0714285714285714,0.128571428571429,1.43014316833318e-19,0.999852323093054 "WP12","Osteoclast Signaling",6,"WP12",16,0.75,0.166666666666667,0.25,1.51229007711679e-12,0.999852323093054 "WP134","Pentose Phosphate Metabolism",9,"WP134",7,1,0,0.142857142857143,0.154107526146787,0.999852323093054 "WP1403","AMP-activated Protein Kinase (AMPK) Signaling",12,"WP1403",69,0.81,0.178571428571429,0.25,7.99040804992212e-20,0.999852323093054 "WP143","Fatty Acid Beta Oxidation",17,"WP143",34,0.79,0.111111111111111,0.111111111111111,6.0888051023505e-05,0.999852323093054 "WP1433","Nucleotide-binding Oligomerization Domain (NOD) pathway",18,"WP1433",41,0.78,0.0625,0.125,4.08325260581342e-05,0.999852323093054 "WP1449","Regulation of toll-like receptor signaling pathway",21,"WP1449",145,0.77,0.117117117117117,0.198198198198198,1.55030261832076e-25,0.999852323093054 "WP1471","Target Of Rapamycin (TOR) Signaling",23,"WP1471",37,0.92,0.0882352941176471,0.117647058823529,8.28904921253337e-06,0.999852323093054 "WP1531","Vitamin D Metabolism",28,"WP1531",10,0.7,0.285714285714286,0.285714285714286,2.36116814219851e-05,0.999852323093054 "WP1544","MicroRNAs in cardiomyocyte hypertrophy",32,"WP1544",101,0.75,0.223684210526316,0.263157894736842,1.45750470372243e-17,0.999852323093054 "WP1589","Folate-Alcohol and Cancer Pathway Hypotheses",36,"WP1589",9,0.89,0.125,0.25,2.91348117795513e-05,0.999852323093054 "WP185","Integrin-mediated Cell Adhesion",50,"WP185",104,0.84,0.195402298850575,0.218390804597701,5.28168194977512e-22,0.999852323093054 "WP1941","Peroxisomal beta-oxidation of tetracosanoyl-CoA",52,"WP1941",4,1,0,0,0.999852323093054,0.999852323093054 "WP195","IL-1 signaling pathway",54,"WP195",57,0.96,0.127272727272727,0.181818181818182,1.5288509675647e-18,0.999852323093054 "WP197","Cholesterol Biosynthesis Pathway",55,"WP197",15,0.93,0.214285714285714,0.285714285714286,2.36116814219851e-05,0.999852323093054 "WP1982","Sterol Regulatory Element-Binding Proteins (SREBP) signalling",58,"WP1982",73,0.88,0.140625,0.171875,1.10524321914212e-13,0.999852323093054 "WP2035","Follicle Stimulating Hormone (FSH) signaling pathway",70,"WP2035",27,0.81,0.181818181818182,0.272727272727273,1.84528135455106e-08,0.999852323093054 "WP205","IL-7 Signaling Pathway",74,"WP205",25,1,0.16,0.2,0.000601597866207179,0.999852323093054 "WP2112","IL17 signaling pathway",78,"WP2112",32,0.84,0.148148148148148,0.222222222222222,1.31802719833037e-09,0.999852323093054 "WP22","IL-9 Signaling Pathway",82,"WP22",19,0.79,0.0666666666666667,0.0666666666666667,0.000601597866207179,0.999852323093054 "WP2249","Metastatic brain tumor",84,"WP2249",28,0.21,0.166666666666667,0.333333333333333,0.00291300857028192,0.999852323093054 "WP2261","Signaling Pathways in Glioblastoma",85,"WP2261",83,0.96,0.2375,0.25,1.45750470372243e-17,0.999852323093054 "WP2272","Pathogenic Escherichia coli infection",87,"WP2272",55,0.85,0.0851063829787234,0.191489361702128,4.18564642105688e-07,0.999852323093054 "WP2289","Drug Induction of Bile Acid Pathway",89,"WP2289",17,0.24,0.25,0.25,6.49286728094462e-06,0.999852323093054 "WP2291","Deregulation of Rab and Rab Effector Genes in Bladder Cancer",92,"WP2291",16,0.94,0.266666666666667,0.266666666666667,3.11005970071626e-15,0.999852323093054 "WP2324","AGE/RAGE pathway",95,"WP2324",66,0.95,0.142857142857143,0.206349206349206,1.45750470372243e-17,0.999852323093054 "WP2333","Trans-sulfuration pathway",98,"WP2333",10,1,0.2,0.2,7.49087453817701e-07,0.999852323093054 "WP2436","Dopamine metabolism",115,"WP2436",14,0.64,0.222222222222222,0.222222222222222,6.78665345557183e-11,0.999852323093054 "WP2447","Amyotrophic lateral sclerosis (ALS)",118,"WP2447",38,0.79,0.166666666666667,0.3,1.30274002920557e-12,0.999852323093054 "WP2485","NAD Biosynthesis II (from tryptophan)",122,"WP2485",8,0.75,0.166666666666667,0.166666666666667,1.2733947666864e-33,0.999852323093054 "WP2509","Nanoparticle triggered autophagic cell death",125,"WP2509",24,0.88,0.142857142857143,0.142857142857143,1.28737203377495e-08,0.999852323093054 "WP2513","Nanoparticle triggered regulated necrosis",126,"WP2513",12,0.92,0,0,0.795485118928105,0.999852323093054 "WP2526","PDGF Pathway",129,"WP2526",40,0.98,0.0769230769230769,0.128205128205128,1.21006371795151e-15,0.999852323093054 "WP2572","Primary Focal Segmental Glomerulosclerosis FSGS",134,"WP2572",74,0.78,0.275862068965517,0.310344827586207,4.81412003815079e-10,0.999852323093054 "WP2637","Structural Pathway of Interleukin 1 (IL-1)",142,"WP2637",50,0.98,0.142857142857143,0.204081632653061,1.21006371795151e-15,0.999852323093054 "WP2643","Nanoparticle-mediated activation of receptor signaling",144,"WP2643",29,0.97,0.178571428571429,0.214285714285714,0.00101315545629077,0.999852323093054 "WP268","Notch Signaling",147,"WP268",47,0.85,0.175,0.225,6.84417911248327e-08,0.999852323093054 "WP2805","exRNA mechanism of action and biogenesis",151,"WP2805",8,0.62,0.2,0.2,0.000217368536815086,0.999852323093054 "WP2813","Mammary gland development pathway - Embryonic development (Stage 1 of 4)",153,"WP2813",18,0.61,0.272727272727273,0.272727272727273,1.1219536394885e-16,0.999852323093054 "WP2853","Endoderm Differentiation",164,"WP2853",146,0.77,0.223214285714286,0.258928571428571,5.00019440781505e-25,0.999852323093054 "WP2857","Mesodermal Commitment Pathway",167,"WP2857",157,0.74,0.206896551724138,0.258620689655172,5.00019440781505e-25,0.999852323093054 "WP286","IL-3 Signaling Pathway",169,"WP286",49,0.9,0.159090909090909,0.204545454545455,1.21006371795151e-15,0.999852323093054 "WP2864","Apoptosis-related network due to altered Notch3 in ovarian cancer",170,"WP2864",54,0.93,0.16,0.28,4.12289297028431e-17,0.999852323093054 "WP2868","TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer",172,"WP2868",5,1,0,0,0.999852323093054,0.999852323093054 "WP2873","Aryl Hydrocarbon Receptor Pathway",174,"WP2873",48,0.65,0.129032258064516,0.225806451612903,4.12289297028431e-17,0.999852323093054 "WP2875","Constitutive Androstane Receptor Pathway",176,"WP2875",32,0.53,0.176470588235294,0.235294117647059,2.9447393377517e-11,0.999852323093054 "WP2876","Pregnane X Receptor pathway",177,"WP2876",33,0.55,0.166666666666667,0.222222222222222,2.9447393377517e-11,0.999852323093054 "WP288","NLR Proteins",181,"WP288",9,0.89,0.125,0.125,0.00237947159212301,0.999852323093054 "WP2884","NRF2 pathway",184,"WP2884",146,0.66,0.1875,0.260416666666667,2.4987918295779e-23,0.999852323093054 "WP2889","Oxytocin signaling",185,"WP2889",4,0.5,0,0,0.999852323093054,0.999852323093054 "WP2916","Interactome of polycomb repressive complex 2 (PRC2) ",189,"WP2916",17,0.94,0.1875,0.3125,6.05665966147348e-07,0.999852323093054 "WP2942","DDX1 as a regulatory component of the Drosha microprocessor",190,"WP2942",9,0.67,0,0,0.990973876560315,0.999852323093054 "WP299","Nuclear Receptors in Lipid Metabolism and Toxicity",192,"WP299",35,0.46,0.25,0.25,1.20099662033474e-06,0.999852323093054 "WP304","Kit receptor signaling pathway",194,"WP304",60,0.98,0.169491525423729,0.220338983050847,1.45750470372243e-17,0.999852323093054 "WP311","Synthesis and Degradation of Ketone Bodies",196,"WP311",5,1,0.2,0.2,6.0888051023505e-05,0.999852323093054 "WP313","Signaling of Hepatocyte Growth Factor Receptor",197,"WP313",34,1,0.176470588235294,0.205882352941176,1.21006371795151e-15,0.999852323093054 "WP325","Triacylglyceride Synthesis",200,"WP325",26,0.54,0,0,0.999852323093054,0.999852323093054 "WP3300","Dual hijack model of Vif in HIV infection",206,"WP3300",9,0.67,0,0.166666666666667,0.118228105072828,0.999852323093054 "WP3302","eIF5A regulation in response to inhibition of the nuclear export system",208,"WP3302",4,0.75,0.333333333333333,0.333333333333333,0.00071352422837791,0.999852323093054 "WP3303","RAC1/PAK1/p38/MMP2 Pathway",209,"WP3303",69,0.9,0.225806451612903,0.274193548387097,3.11796204582401e-18,0.999852323093054 "WP357","Fatty Acid Biosynthesis",219,"WP357",22,0.91,0.2,0.2,1.10524321914212e-13,0.999852323093054 "WP3593","MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma",224,"WP3593",9,0.78,0,0,0.999852323093054,0.999852323093054 "WP363","Wnt Signaling Pathway (Netpath)",237,"WP363",53,0.91,0.208333333333333,0.208333333333333,1.45750470372243e-17,0.999852323093054 "WP3630","NAD metabolism, sirtuins and aging",238,"WP3630",11,0.91,0.2,0.3,2.25748011539398e-08,0.999852323093054 "WP3634","Insulin signalling in human adipocytes (normal condition)",240,"WP3634",8,1,0.125,0.125,7.99040804992212e-20,0.999852323093054 "WP3635","Insulin signalling in human adipocytes (diabetic condition)",241,"WP3635",8,1,0.125,0.125,7.99040804992212e-20,0.999852323093054 "WP364","IL-6 signaling pathway",242,"WP364",43,0.95,0.24390243902439,0.24390243902439,1.55030261832076e-25,0.999852323093054 "WP3644","NAD+ metabolism",244,"WP3644",16,0.88,0.142857142857143,0.285714285714286,2.25748011539398e-08,0.999852323093054 "WP3645","NAD+ biosynthetic pathways",245,"WP3645",22,0.77,0.176470588235294,0.294117647058824,2.25748011539398e-08,0.999852323093054 "WP3651","Pathways Affected in Adenoid Cystic Carcinoma",247,"WP3651",66,0.85,0.196428571428571,0.25,2.89465973850597e-12,0.999852323093054 "WP3655","Hypothetical Craniofacial Development Pathway",248,"WP3655",8,0.75,0.166666666666667,0.166666666666667,0.00407427421601939,0.999852323093054 "WP3656","Interleukin-1 Induced Activation of NF-kappa-B",249,"WP3656",11,0.91,0.1,0.2,0.00279989180752429,0.999852323093054 "WP3658","Wnt/beta-catenin Signaling Pathway in Leukemia",251,"WP3658",26,0.81,0.333333333333333,0.333333333333333,1.28160819617811e-23,0.999852323093054 "WP366","TGF-beta Signaling Pathway",252,"WP366",133,0.96,0.2109375,0.234375,1.4645909158934e-29,0.999852323093054 "WP3668","Hypothesized Pathways in Pathogenesis of Cardiovascular Disease",255,"WP3668",25,0.92,0.217391304347826,0.304347826086957,1.91116166189054e-21,0.999852323093054 "WP3674","Tgif disruption of Shh signaling",258,"WP3674",9,0.44,0,0,0.999852323093054,0.999852323093054 "WP3676","BDNF-TrkB Signaling",259,"WP3676",34,0.88,0.166666666666667,0.2,1.84528135455106e-08,0.999852323093054 "WP368","Mitochondrial LC-Fatty Acid Beta-Oxidation",262,"WP368",17,0.94,0.0625,0.0625,0.0167383786864681,0.999852323093054 "WP3680","Association Between Physico-Chemical Features and Toxicity Associated Pathways",263,"WP3680",68,0.81,0.163636363636364,0.2,1.46702371634426e-15,0.999852323093054 "WP3844","PI3K-AKT-mTOR signaling pathway and therapeutic opportunities",267,"WP3844",30,1,0.2,0.2,6.62772818839576e-10,0.999852323093054 "WP3849","MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ",269,"WP3849",12,1,0.166666666666667,0.25,1.31802719833037e-09,0.999852323093054 "WP3851","TLR4 Signaling and Tolerance",271,"WP3851",30,0.83,0.08,0.16,1.55030261832076e-25,0.999852323093054 "WP3853","ERK Pathway in Huntington's Disease",272,"WP3853",15,0.87,0.230769230769231,0.307692307692308,1.84528135455106e-08,0.999852323093054 "WP3858","Toll-like Receptor Signaling related to MyD88",273,"WP3858",32,0.84,0,0.111111111111111,0.114048118916392,0.999852323093054 "WP3863","T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection",275,"WP3863",62,0.81,0.14,0.22,1.21006371795151e-15,0.999852323093054 "WP3865","Novel intracellular components of RIG-I-like receptor (RLR) pathway",276,"WP3865",61,0.84,0.137254901960784,0.235294117647059,3.37870774082303e-13,0.999852323093054 "WP3869","Cannabinoid receptor signaling",277,"WP3869",29,0.79,0.0869565217391304,0.130434782608696,3.92161302035637e-08,0.999852323093054 "WP3871","Valproic acid pathway",278,"WP3871",13,0.62,0.125,0.125,0.0102047891408715,0.999852323093054 "WP3874","Canonical and Non-Canonical TGF-B signaling",280,"WP3874",17,1,0.0588235294117647,0.235294117647059,1.47923810515956e-16,0.999852323093054 "WP3877","Simplified Depiction of MYD88 Distinct Input-Output Pathway",283,"WP3877",19,0.74,0,0.214285714285714,0.0594386193019534,0.999852323093054 "WP3878","ATM Signaling Network in Development and Disease ",284,"WP3878",46,0.89,0.219512195121951,0.268292682926829,2.50026382158374e-16,0.999852323093054 "WP3879","4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression",285,"WP3879",18,1,0.111111111111111,0.111111111111111,2.45237666239285e-07,0.999852323093054 "WP391","Mitochondrial Gene Expression",290,"WP391",20,0.8,0.125,0.1875,2.9447393377517e-11,0.999852323093054 "WP3924","Hfe effect on hepcidin production",292,"WP3924",7,0.57,0.25,0.25,0.00378182889135815,0.999852323093054 "WP3925","Amino Acid metabolism",293,"WP3925",91,0.73,0.166666666666667,0.227272727272727,2.58938282317479e-38,0.999852323093054 "WP3927","BMP Signaling Pathway in Eyelid Development",295,"WP3927",20,0.8,0.1875,0.25,1.1219536394885e-16,0.999852323093054 "WP3933","Kennedy pathway from Sphingolipids",300,"WP3933",15,0.8,0.0833333333333333,0.0833333333333333,0.000153115641692463,0.999852323093054 "WP3934","Leptin and adiponectin",301,"WP3934",10,0.8,0.125,0.125,1.13349503425421e-06,0.999852323093054 "WP3937","Microglia Pathogen Phagocytosis Pathway",303,"WP3937",40,0.9,0.0833333333333333,0.0833333333333333,1.57756315705304e-09,0.999852323093054 "WP3938","miR-222 in Exercise-Induced Cardiac Growth",304,"WP3938",4,1,0,0,0.999852323093054,0.999852323093054 "WP3943","Robo4 and VEGF Signaling Pathways Crosstalk",308,"WP3943",6,1,0.333333333333333,0.333333333333333,1.76304737966141e-10,0.999852323093054 "WP3969","H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity",318,"WP3969",16,0.88,0.214285714285714,0.214285714285714,7.1806031181162e-15,0.999852323093054 "WP3971","Role of Osx and miRNAs in tooth development",319,"WP3971",36,0.28,0.2,0.2,1.74501293167954e-14,0.999852323093054 "WP3981","miRNA regulation of prostate cancer signaling pathways",321,"WP3981",59,0.54,0.15625,0.21875,1.28737203377495e-08,0.999852323093054 "WP399","Wnt Signaling Pathway and Pluripotency",323,"WP399",107,0.8,0.232558139534884,0.290697674418605,1.45750470372243e-17,0.999852323093054 "WP400","p38 MAPK Signaling Pathway",327,"WP400",34,0.97,0.181818181818182,0.242424242424242,4.7856489956754e-16,0.999852323093054 "WP4018","Pathways in clear cell renal cell carcinoma",330,"WP4018",87,0.91,0.164556962025316,0.189873417721519,1.10524321914212e-13,0.999852323093054 "WP405","Eukaryotic Transcription Initiation",334,"WP405",43,0.95,0.0975609756097561,0.146341463414634,2.41984712730741e-07,0.999852323093054 "WP410","Exercise-induced Circadian Regulation",336,"WP410",49,0.9,0.272727272727273,0.295454545454545,1.86144948015588e-42,0.999852323093054 "WP4136","Fibrin Complement Receptor 3 Signaling Pathway",338,"WP4136",42,0.71,0.0666666666666667,0.166666666666667,1.55030261832076e-25,0.999852323093054 "WP4141","PI3K/AKT/mTOR - VitD3 Signalling",339,"WP4141",22,0.86,0.263157894736842,0.263157894736842,3.87043570690072e-12,0.999852323093054 "WP4146","Macrophage markers",341,"WP4146",9,1,0,0.111111111111111,0.21102640351702,0.999852323093054 "WP4150","Wnt Signaling in Kidney Disease",345,"WP4150",39,0.69,0.222222222222222,0.222222222222222,8.33920870140507e-09,0.999852323093054 "WP4155","Endometrial cancer",347,"WP4155",63,0.94,0.152542372881356,0.220338983050847,1.04633266994318e-15,0.999852323093054 "WP4186","Somatroph axis (GH) and its relationship to dietary restriction and aging",352,"WP4186",6,1,0.333333333333333,0.333333333333333,2.25748011539398e-08,0.999852323093054 "WP4189","Mevalonate arm of cholesterol biosynthesis pathway with inhibitors",353,"WP4189",2,1,0,0,0.999852323093054,0.999852323093054 "WP4197","The human immune response to tuberculosis",356,"WP4197",23,1,0.130434782608696,0.130434782608696,0.000341914298724229,0.999852323093054 "WP4205","MET in type 1 papillary renal cell carcinoma",358,"WP4205",59,0.88,0.115384615384615,0.173076923076923,3.90142119029615e-06,0.999852323093054 "WP4206","Hereditary leiomyomatosis and renal cell carcinoma pathway",359,"WP4206",20,0.95,0.105263157894737,0.210526315789474,2.03101031117154e-10,0.999852323093054 "WP4210","Tryptophan catabolism leading to NAD+ production",360,"WP4210",16,0.69,0.0909090909090909,0.0909090909090909,1.2733947666864e-33,0.999852323093054 "WP4217","Ebola Virus Pathway on Host",363,"WP4217",132,0.89,0.135593220338983,0.186440677966102,7.15702783093164e-17,0.999852323093054 "WP422","MAPK Cascade",364,"WP422",33,1,0.212121212121212,0.272727272727273,1.06179313771239e-06,0.999852323093054 "WP4223","Ras Signaling",367,"WP4223",186,0.76,0.204225352112676,0.26056338028169,2.6982385516733e-21,0.999852323093054 "WP4236","Disorders of the Krebs cycle",372,"WP4236",7,1,0.142857142857143,0.142857142857143,0.000542153786249434,0.999852323093054 "WP4239","Epithelial to mesenchymal transition in colorectal cancer",373,"WP4239",164,0.78,0.1953125,0.2578125,5.10653311534479e-29,0.999852323093054 "WP4241","Type 2 papillary renal cell carcinoma",375,"WP4241",36,0.83,0.133333333333333,0.166666666666667,6.62772818839576e-10,0.999852323093054 "WP4255","Non-small cell lung cancer",377,"WP4255",72,0.93,0.149253731343284,0.238805970149254,1.45750470372243e-17,0.999852323093054 "WP4263","Pancreatic adenocarcinoma pathway",381,"WP4263",89,0.96,0.141176470588235,0.211764705882353,1.47923810515956e-16,0.999852323093054 "WP4271","Vitamin B12 Disorders",383,"WP4271",13,0.69,0,0.222222222222222,0.105553301023444,0.999852323093054 "WP4292","Methionine metabolism leading to Sulphur Amino Acids and related disorders",389,"WP4292",11,0.82,0.222222222222222,0.222222222222222,5.6500805039415e-14,0.999852323093054 "WP430","Statin Pathway",394,"WP430",33,0.45,0.133333333333333,0.266666666666667,0.00133659811986492,0.999852323093054 "WP4313","Ferroptosis",399,"WP4313",40,0.9,0.138888888888889,0.194444444444444,1.14291084616521e-05,0.999852323093054 "WP4331","Neovascularisation processes",404,"WP4331",37,1,0.189189189189189,0.27027027027027,3.37870774082303e-13,0.999852323093054 "WP4352","Ciliary landscape",409,"WP4352",220,0.9,0.137055837563452,0.208121827411168,4.19419091059679e-15,0.999852323093054 "WP4389","Bile Acids synthesis and enterohepatic circulation ",413,"WP4389",13,0.38,0,0.2,0.191601747736878,0.999852323093054 "WP4396","Nonalcoholic fatty liver disease",414,"WP4396",160,0.84,0.133333333333333,0.207407407407407,1.55030261832076e-25,0.999852323093054 "WP4397","Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors",415,"WP4397",3,0.67,0,0,0.999852323093054,0.999852323093054 "WP4478","LTF danger signal response pathway",419,"WP4478",20,0.7,0.0714285714285714,0.214285714285714,1.55030261832076e-25,0.999852323093054 "WP4479","Supression of HMGB1 mediated inflammation by THBD",420,"WP4479",9,1,0,0.111111111111111,0.452666162731714,0.999852323093054 "WP4494","Selective expression of chemokine receptors during T-cell polarization",427,"WP4494",29,0.55,0.0625,0.125,0.00407427421601939,0.999852323093054 "WP4496","Signal transduction through IL1R",429,"WP4496",35,0.86,0.133333333333333,0.233333333333333,1.55030261832076e-25,0.999852323093054 "WP4504","Cysteine and methionine catabolism",431,"WP4504",15,0.87,0.153846153846154,0.153846153846154,5.6500805039415e-14,0.999852323093054 "WP4506","Tyrosine Metabolism",432,"WP4506",4,0.25,0,0,0.999852323093054,0.999852323093054 "WP4518","Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases",434,"WP4518",10,0.5,0.2,0.2,0.000377573164229441,0.999852323093054 "WP4521","Glycosylation and related congenital defects",436,"WP4521",25,1,0.12,0.16,1.02496252421453e-08,0.999852323093054 "WP4523","Classical pathway of steroidogenesis, including diseases",438,"WP4523",16,0.31,0,0.2,0.273007477872406,0.999852323093054 "WP4524","The alternative pathway of fetal androgen synthesis",439,"WP4524",12,0.33,0.25,0.25,2.8033361067803e-09,0.999852323093054 "WP453","Inflammatory Response Pathway",440,"WP453",33,0.67,0.0909090909090909,0.181818181818182,0.000442098767154395,0.999852323093054 "WP4532","Intraflagellar transport proteins binding to dynein",441,"WP4532",27,0.93,0.08,0.16,0.00558066527342552,0.999852323093054 "WP4533","Transcription co-factors SKI and SKIL protein partners",442,"WP4533",18,1,0.166666666666667,0.277777777777778,1.54778757247964e-06,0.999852323093054 "WP4536","Genes related to primary cilium development (based on CRISPR)",445,"WP4536",103,0.92,0.105263157894737,0.189473684210526,8.57900007846234e-13,0.999852323093054 "WP4539","Synaptic signaling pathways associated with autism spectrum disorder",448,"WP4539",51,0.76,0.256410256410256,0.256410256410256,9.26038985479124e-09,0.999852323093054 "WP4542","Overview of leukocyte-intrinsic Hippo pathway functions",451,"WP4542",36,0.86,0.161290322580645,0.258064516129032,1.54778757247964e-06,0.999852323093054 "WP4553","FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma",455,"WP4553",38,0.29,0.181818181818182,0.272727272727273,3.04356671038824e-07,0.999852323093054 "WP4559","Interactions between immune cells and microRNAs in tumor microenvironment",457,"WP4559",40,0.6,0.125,0.25,1.47923810515956e-16,0.999852323093054 "WP4561","Cell migration and invasion through p75NTR",459,"WP4561",31,0.9,0.214285714285714,0.285714285714286,3.88351886854851e-13,0.999852323093054 "WP4564","Neural Crest Cell Migration during Development",461,"WP4564",41,0.8,0.151515151515152,0.242424242424242,1.21006371795151e-15,0.999852323093054 "WP4565","Neural Crest Cell Migration in Cancer",462,"WP4565",44,0.82,0.166666666666667,0.25,1.21006371795151e-15,0.999852323093054 "WP4577","Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway",465,"WP4577",44,0.98,0.0930232558139535,0.116279069767442,0.000303680199088757,0.999852323093054 "WP4595","Urea cycle and associated pathways",472,"WP4595",21,0.76,0.25,0.3125,1.21134935033961e-14,0.999852323093054 "WP4629","Computational Model of Aerobic Glycolysis",473,"WP4629",12,0.92,0.181818181818182,0.181818181818182,1.94971495989183e-05,0.999852323093054 "WP4655","Cytosolic DNA-sensing pathway",475,"WP4655",76,0.72,0.109090909090909,0.145454545454545,1.55030261832076e-25,0.999852323093054 "WP4659","Gastrin Signaling Pathway",479,"WP4659",114,0.92,0.180952380952381,0.238095238095238,4.7856489956754e-16,0.999852323093054 "WP4674","Head and Neck Squamous Cell Carcinoma",484,"WP4674",70,0.94,0.121212121212121,0.166666666666667,1.47923810515956e-16,0.999852323093054 "WP4685","Melanoma",485,"WP4685",68,0.93,0.174603174603175,0.26984126984127,1.21006371795151e-15,0.999852323093054 "WP47","Hedgehog Signaling Pathway Netpath",487,"WP47",16,0.75,0.0833333333333333,0.25,0.0317273821116764,0.999852323093054 "WP4705","Pathways of nucleic acid metabolism and innate immune sensing",488,"WP4705",16,0.81,0.153846153846154,0.153846153846154,1.16208386478435e-12,0.999852323093054 "WP4718","Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)",489,"WP4718",47,0.87,0.219512195121951,0.268292682926829,1.16398114740138e-08,0.999852323093054 "WP4721","Eicosanoid metabolism via Lipo Oxygenases (LOX)",492,"WP4721",29,0.69,0.2,0.25,4.45382103461115e-22,0.999852323093054 "WP4722","Glycerolipids and Glycerophospholipids",493,"WP4722",24,0.75,0.0555555555555556,0.0555555555555556,0.000153115641692463,0.999852323093054 "WP4723","Omega-3/Omega-6 FA synthesis",494,"WP4723",15,0.73,0,0.0909090909090909,0.296626199889639,0.999852323093054 "WP4726","Sphingolipid Metabolism (integrated pathway)",497,"WP4726",25,0.84,0.19047619047619,0.238095238095238,1.3073328528498e-06,0.999852323093054 "WP4742","Ketogenesis and Ketolysis",499,"WP4742",8,1,0.125,0.125,6.0888051023505e-05,0.999852323093054 "WP4746","Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism",500,"WP4746",95,0.69,0.227272727272727,0.272727272727273,2.44977316588364e-24,0.999852323093054 "WP4747","Netrin-UNC5B signaling Pathway",501,"WP4747",52,0.85,0.181818181818182,0.272727272727273,2.5665992363522e-08,0.999852323093054 "WP4751","HIPK2 in kidney fibrosis",502,"WP4751",2,1,0,0,0.999852323093054,0.999852323093054 "WP4753","Nucleotide Excision Repair",504,"WP4753",44,0.98,0.255813953488372,0.27906976744186,3.57124737003596e-13,0.999852323093054 "WP4767","FGFR3 signalling in chondrocyte proliferation and terminal differentiation",509,"WP4767",27,0.89,0.166666666666667,0.25,1.60955895014834e-18,0.999852323093054 "WP477","Cytoplasmic Ribosomal Proteins",510,"WP477",91,0.93,0.129411764705882,0.164705882352941,8.56966962716958e-10,0.999852323093054 "WP4792","Purine metabolism",511,"WP4792",13,0.85,0.272727272727273,0.272727272727273,3.92279863878209e-05,0.999852323093054 "WP481","Insulin Signaling",512,"WP481",161,0.93,0.186666666666667,0.246666666666667,2.30627807010563e-26,0.999852323093054 "WP49","IL-2 Signaling Pathway",513,"WP49",42,0.98,0.195121951219512,0.24390243902439,1.21006371795151e-15,0.999852323093054 "WP496","Steroid Biosynthesis",514,"WP496",10,0.4,0,0.25,0.386085732506969,0.999852323093054 "WP500","Glycogen Synthesis and Degradation",516,"WP500",40,0.9,0.138888888888889,0.194444444444444,9.51262628208688e-25,0.999852323093054 "WP51","Regulation of Actin Cytoskeleton",518,"WP51",151,0.77,0.213675213675214,0.273504273504274,1.04633266994318e-15,0.999852323093054 "WP521","Amino acid conjugation of benzoic acid",520,"WP521",5,0.2,0,0,0.999852323093054,0.999852323093054 "WP524","G13 Signaling Pathway",521,"WP524",41,0.85,0.2,0.2,6.63243812483213e-11,0.999852323093054 "WP528","Acetylcholine Synthesis",522,"WP528",7,0.57,0,0,0.999852323093054,0.999852323093054 "WP534","Glycolysis and Gluconeogenesis",526,"WP534",45,0.73,0.121212121212121,0.121212121212121,7.99040804992212e-20,0.999852323093054 "WP560","TGF-beta Receptor Signaling",532,"WP560",58,0.79,0.217391304347826,0.260869565217391,1.47923810515956e-16,0.999852323093054 "WP581","EPO Receptor Signaling",535,"WP581",26,0.96,0.08,0.08,0.000601597866207179,0.999852323093054 "WP585","Interferon type I signaling pathways",536,"WP585",55,0.95,0.173076923076923,0.230769230769231,9.45573250233619e-09,0.999852323093054 "WP61","Notch Signaling Pathway Netpath",537,"WP61",63,0.9,0.157894736842105,0.280701754385965,4.8712821556021e-23,0.999852323093054 "WP615","Senescence and Autophagy in Cancer",538,"WP615",108,0.86,0.193548387096774,0.258064516129032,1.55030261832076e-25,0.999852323093054 "WP623","Oxidative phosphorylation",540,"WP623",62,0.6,0,0.0540540540540541,0.0626324188453113,0.999852323093054 "WP673","ErbB Signaling Pathway",542,"WP673",91,0.89,0.209876543209877,0.259259259259259,3.46021469111041e-20,0.999852323093054 "WP678","Arachidonate Epoxygenase / Epoxide Hydrolase",543,"WP678",7,0.71,0.2,0.2,4.43345799464762e-09,0.999852323093054 "WP688","Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)",544,"WP688",5,0.6,0,0,0.999852323093054,0.999852323093054 "WP690","Polyol Pathway",546,"WP690",4,0.75,0,0,0.855645046418417,0.999852323093054 "WP692","Sulfation Biotransformation Reaction",548,"WP692",19,0.32,0,0,0.999852323093054,0.999852323093054 "WP694","Arylamine metabolism",549,"WP694",6,0.33,0,0,0.999852323093054,0.999852323093054 "WP696","Benzo(a)pyrene metabolism",550,"WP696",9,0.78,0,0.142857142857143,0.186101834726753,0.999852323093054 "WP697","Estrogen metabolism",551,"WP697",19,0.47,0,0,0.999852323093054,0.999852323093054 "WP698","Glucuronidation",552,"WP698",26,0.35,0.222222222222222,0.222222222222222,2.6913627863713e-23,0.999852323093054 "WP699","Aflatoxin B1 metabolism",553,"WP699",7,0.43,0,0,0.999852323093054,0.999852323093054 "WP702","Metapathway biotransformation Phase I and II",554,"WP702",188,0.48,0.133333333333333,0.188888888888889,2.4987918295779e-23,0.999852323093054 "WP710","DNA Damage Response (only ATM dependent)",558,"WP710",115,0.87,0.13,0.21,1.57756315705304e-09,0.999852323093054 "WP712","Estrogen signaling pathway",559,"WP712",23,0.91,0.19047619047619,0.333333333333333,1.21006371795151e-15,0.999852323093054 "WP716","Vitamin A and Carotenoid Metabolism",560,"WP716",44,0.5,0.181818181818182,0.272727272727273,9.28054409606823e-14,0.999852323093054 "WP733","Serotonin Receptor 2 and STAT3 Signaling",563,"WP733",4,0.75,0.333333333333333,0.333333333333333,0.0212542319346549,0.999852323093054 "WP75","Toll-like Receptor Signaling Pathway",565,"WP75",104,0.75,0.0897435897435897,0.179487179487179,1.55030261832076e-25,0.999852323093054 "WP78","TCA Cycle (aka Krebs or citric acid cycle)",566,"WP78",18,1,0,0.0555555555555556,0.345480440691871,0.999852323093054 "WP80","Nucleotide GPCRs",567,"WP80",11,0.73,0,0,0.999852323093054,0.999852323093054 "WP127","IL-5 Signaling Pathway",7,"WP127",40,0.95,0.236842105263158,0.263157894736842,1.21006371795151e-15,0.999852323093054 "WP138","Androgen receptor signaling pathway",11,"WP138",91,0.9,0.195121951219512,0.25609756097561,1.33825325438479e-13,0.999852323093054 "WP1425","Bone Morphogenic Protein (BMP) Signalling and Regulation",16,"WP1425",12,0.83,0.1,0.2,0.0044135122745415,0.999852323093054 "WP1559","TFs Regulate miRNAs related to cardiac hypertrophy",34,"WP1559",12,0.58,0,0.142857142857143,0.452666162731714,0.999852323093054 "WP1946","Cori Cycle",53,"WP1946",17,0.82,0.142857142857143,0.142857142857143,7.99040804992212e-20,0.999852323093054 "WP2034","Leptin signaling pathway",69,"WP2034",76,0.99,0.213333333333333,0.266666666666667,6.63243812483213e-11,0.999852323093054 "WP2290","RalA downstream regulated genes",91,"WP2290",12,0.92,0.181818181818182,0.181818181818182,1.57756315705304e-09,0.999852323093054 "WP23","B Cell Receptor Signaling Pathway",93,"WP23",98,0.94,0.184782608695652,0.260869565217391,1.45750470372243e-17,0.999852323093054 "WP2328","Allograft Rejection",96,"WP2328",90,0.69,0.17741935483871,0.209677419354839,2.86780567028817e-25,0.999852323093054 "WP2332","Interleukin-11 Signaling Pathway",97,"WP2332",44,0.91,0.225,0.25,3.51846221320189e-12,0.999852323093054 "WP2795","Cardiac Hypertrophic Response",149,"WP2795",57,0.89,0.196078431372549,0.254901960784314,2.08918249834541e-15,0.999852323093054 "WP3614","Photodynamic therapy-induced HIF-1 survival signaling",233,"WP3614",37,0.89,0.181818181818182,0.242424242424242,3.51846221320189e-12,0.999852323093054 "WP3891","Benzene metabolism",287,"WP3891",6,0.5,0,0,0.999852323093054,0.999852323093054 "WP3915","Angiopoietin Like Protein 8 Regulatory Pathway",291,"WP3915",132,0.89,0.136752136752137,0.170940170940171,7.99040804992212e-20,0.999852323093054 "WP3926","ApoE and miR-146 in inflammation and atherosclerosis",294,"WP3926",9,0.89,0,0.125,0.114048118916392,0.999852323093054 "WP404","Nucleotide Metabolism",333,"WP404",19,0.95,0.166666666666667,0.166666666666667,3.57124737003596e-13,0.999852323093054 "WP4216","Chromosomal and microsatellite instability in colorectal cancer ",362,"WP4216",74,0.96,0.211267605633803,0.267605633802817,1.47923810515956e-16,0.999852323093054 "WP4269","Ethanol metabolism resulting in production of ROS by CYP2E1",382,"WP4269",10,0.9,0.111111111111111,0.333333333333333,7.45368111307164e-07,0.999852323093054 "WP4288","MTHFR deficiency",387,"WP4288",27,0.7,0.315789473684211,0.315789473684211,1.69249742410717e-08,0.999852323093054 "WP4301","Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells",396,"WP4301",18,1,0.166666666666667,0.222222222222222,9.01134422889796e-05,0.999852323093054 "WP4324","Mitochondrial complex I assembly model OXPHOS system",402,"WP4324",56,0.8,0,0.0222222222222222,0.0626324188453113,0.999852323093054 "WP4329","miRNAs involvement in the immune response in sepsis",403,"WP4329",64,0.5,0.0625,0.1875,1.55030261832076e-25,0.999852323093054 "WP438","Non-homologous end joining",412,"WP438",11,0.91,0.1,0.1,0.00934439177317729,0.999852323093054 "WP4495","IL-10 Anti-inflammatory Signaling Pathway ",428,"WP4495",12,0.92,0.181818181818182,0.272727272727273,1.55030261832076e-25,0.999852323093054 "WP4507","Molybdenum cofactor (Moco) biosynthesis",433,"WP4507",7,1,0.142857142857143,0.285714285714286,3.39506009152496e-24,0.999852323093054 "WP4534","Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms",443,"WP4534",48,0.92,0.159090909090909,0.272727272727273,8.80436312071741e-23,0.999852323093054 "WP4558","Overview of interferons-mediated signaling pathway",456,"WP4558",37,0.38,0.214285714285714,0.214285714285714,0.000341914298724229,0.999852323093054 "WP4566","Translation inhibitors in chronically activated PDGFRA cells",463,"WP4566",48,0.94,0.177777777777778,0.2,8.56966962716958e-10,0.999852323093054 "WP4582","Cancer immunotherapy by CTLA4 blockade",466,"WP4582",15,0.8,0,0,0.835939678356078,0.999852323093054 "WP4656","Joubert Syndrome",476,"WP4656",77,0.9,0.130434782608696,0.217391304347826,4.67701164770016e-10,0.999852323093054 "WP501","GPCRs, Class C Metabotropic glutamate, pheromone",517,"WP501",16,0.31,0,0,0.999852323093054,0.999852323093054 "WP619","Type II interferon signaling (IFNG)",539,"WP619",37,0.84,0.193548387096774,0.258064516129032,9.44618578094348e-09,0.999852323093054 "WP69","T-Cell antigen Receptor (TCR) Signaling Pathway",545,"WP69",91,0.9,0.0975609756097561,0.182926829268293,1.55030261832076e-25,0.999852323093054 "WP691","Tamoxifen metabolism",547,"WP691",21,0.24,0.2,0.2,0.0372370714105519,0.999852323093054 "WP732","Serotonin Receptor 2 and ELK-SRF/GATA4 signaling",562,"WP732",20,0.75,0.2,0.266666666666667,6.52294438984146e-17,0.999852323093054 "WP1981","Thyroxine (Thyroid Hormone) Production",57,"WP1981",6,0,NA,NA,NA,NA "WP2491","Diclofenac Metabolic Pathway",123,"WP2491",4,0,NA,NA,NA,NA "WP2536","Colchicine Metabolic Pathway",131,"WP2536",1,0,NA,NA,NA,NA "WP2596","Gastric acid production",137,"WP2596",7,0,NA,NA,NA,NA "WP2597","Secretion of Hydrochloric Acid in Parietal Cells",138,"WP2597",5,0,NA,NA,NA,NA "WP2640","Aripiprazole Metabolic Pathway",143,"WP2640",2,0,NA,NA,NA,NA "WP2646","Lidocaine metabolism",146,"WP2646",2,0,NA,NA,NA,NA "WP2816","Felbamate Metabolism",156,"WP2816",2,0,NA,NA,NA,NA "WP3627","Gut-Liver Indole Metabolism ",236,"WP3627",1,0,NA,NA,NA,NA "WP3666","Metabolism of Dichloroethylene by CYP450",254,"WP3666",1,0,NA,NA,NA,NA "WP4174","Metabolism of Tetrahydrocannabinol (THC)",351,"WP4174",2,0,NA,NA,NA,NA "WP4194","Hormonal control of Pubertal Growth Spurt",355,"WP4194",2,0,NA,NA,NA,NA "WP4233","Acrylamide Biotransformation and Exposure Biomarkers",371,"WP4233",1,0,NA,NA,NA,NA "WP661","Glucose Homeostasis",541,"WP661",1,0,NA,NA,NA,NA