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46 KiB
46 KiB
| 1 | ID | Description | setSize | enrichmentScore | NES | pvalue | p.adjust | qvalues | rank | leading_edge | core_enrichment | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | WP2446 | WP2446 | Retinoblastoma Gene in Cancer | 87 | 0.636565973412448 | 2.07894768186214 | 0.00165837479270315 | 0.0136986301369863 | 0.00729992790194665 | 4697 | tags=54%, list=19%, signal=44% | TOP2A/ANLN/POLE2/KIF4A/CCNB1/CCNA2/TTK/CHEK1/PLK4/MCM4/CCNB2/CDK1/RRM2/TYMS/CDC45/RFC4/CCNE2/ORC1/TFDP1/CCNE1/SKP2/CDT1/CDC25A/E2F2/CDC7/FANCG/MSH6/MCM6/BARD1/POLE/PRKDC/E2F3/SMC2/MCM7/RFC5/STMN1/DHFR/RFC3/RPA3/WEE1/HLTF/PRIM1/E2F1/HMGB2/PCNA/H2AFZ/MCM3 |
| 3 | WP179 | WP179 | Cell Cycle | 120 | 0.514478582141183 | 1.74942320154924 | 0.00166666666666667 | 0.0136986301369863 | 0.00729992790194665 | 4923 | tags=38%, list=20%, signal=31% | CDKN2A/CDC25C/CCNB1/CCNA2/TTK/CHEK1/CDC6/PLK1/ORC6/CDC20/MCM4/BUB1/CCNB2/CDK1/ESPL1/DBF4/CDC45/CCNE2/ORC1/PTTG1/TFDP1/MCM2/CCNE1/PKMYT1/SKP2/CDC25A/SMC1B/E2F2/CDC7/MCM6/PRKDC/E2F3/E2F5/CHEK2/MCM7/RBL1/CDKN2C/WEE1/GADD45A/E2F1/ORC2/PCNA/ATM/MCM3/ANAPC11/BUB3 |
| 4 | WP4016 | WP4016 | DNA IR-damage and cellular response via ATR | 80 | 0.608265656044446 | 1.96395220508954 | 0.00167785234899329 | 0.0136986301369863 | 0.00729992790194665 | 4611 | tags=44%, list=19%, signal=36% | CDC25C/BRIP1/CHEK1/PLK1/EXO1/FANCI/FOXM1/CDK1/CDC45/FANCD2/MSH2/FANCA/MCM2/BRCA1/RAD51/CLSPN/BRCA2/FEN1/TOPBP1/BARD1/POLB/PRKDC/EEF1E1/H2AFX/CHEK2/RMI1/CLK2/RBBP8/RFWD3/PALB2/E2F1/PCNA/SEM1/ATM/MRE11 |
| 5 | WP2369 | WP2369 | Histone Modifications | 67 | 0.622040510738319 | 1.9314019320563 | 0.00174825174825175 | 0.0136986301369863 | 0.00729992790194665 | 3552 | tags=40%, list=15%, signal=34% | EZH2/HIST1H4H/HIST1H4C/HIST1H3H/HIST1H4E/SUV39H2/HIST1H3B/HIST1H3J/HIST1H3D/HIST1H4D/HIST1H4I/HIST1H3C/HIST1H4B/HIST1H3F/EED/HIST1H4F/SMYD3/HIST1H4A/HIST1H3I/HIST1H4L/HIST1H3A/HIST4H4/HIST1H3G/HIST1H4J/HIST1H4K/KMT5C/SMYD5 |
| 6 | WP466 | WP466 | DNA Replication | 42 | 0.682437853191023 | 1.93537269381962 | 0.00177619893428064 | 0.0136986301369863 | 0.00729992790194665 | 4697 | tags=57%, list=19%, signal=46% | POLE2/CDC6/ORC6/MCM4/MCM10/DBF4/CDC45/RFC4/ORC1/MCM2/CDT1/GMNN/CDC7/MCM6/PRIM2/POLE/MCM7/RFC5/RFC3/RPA3/PRIM1/ORC2/PCNA/MCM3 |
| 7 | WP2361 | WP2361 | Gastric Cancer Network 1 | 29 | 0.686964138085659 | 1.80275060612194 | 0.00178890876565295 | 0.0136986301369863 | 0.00729992790194665 | 3244 | tags=52%, list=13%, signal=45% | CENPF/TOP2A/TPX2/UBE2C/ECT2/E2F7/MCM4/MYBL2/KIF15/AURKA/KIF20B/S100P/RUVBL1/HIST4H4/ACTL6A |
| 8 | WP357 | WP357 | Fatty Acid Biosynthesis | 22 | -0.726399194516133 | -1.84886866105561 | 0.00223713646532438 | 0.0136986301369863 | 0.00729992790194665 | 4344 | tags=64%, list=18%, signal=52% | ECH1/ACACA/ECHDC1/FASN/SCD/ACSL5/ACAA2/ACSL4/DECR1/PECR/ACSS2/ACACB/ACSL1 |
| 9 | WP545 | WP545 | Complement Activation | 22 | -0.756514524093489 | -1.92551974973147 | 0.00223713646532438 | 0.0136986301369863 | 0.00729992790194665 | 2934 | tags=59%, list=12%, signal=52% | C3/C1QC/C8B/C4A/C1QA/C4B/C7/C1QB/CFP/C5/CFD/MASP1 |
| 10 | WP127 | WP127 | IL-5 Signaling Pathway | 40 | -0.642749664204508 | -1.87301769330181 | 0.00227272727272727 | 0.0136986301369863 | 0.00729992790194665 | 3731 | tags=52%, list=15%, signal=45% | SYK/GSK3B/RAF1/MAP2K1/MAPK3/AKT1/IL2/RPS6KA1/FOS/GRB2/CSF2RB/STAT5B/JAK1/STAT3/STAT5A/MAPK1/PIK3R1/JUN/FOXO3/BTK |
| 11 | WP3937 | WP3937 | Microglia Pathogen Phagocytosis Pathway | 40 | -0.693804651206547 | -2.02179551351968 | 0.00227272727272727 | 0.0136986301369863 | 0.00729992790194665 | 3031 | tags=55%, list=12%, signal=48% | FCGR1A/NCF4/PLCG2/C1QC/VAV1/RAC2/ITGB2/SIGLEC7/PIK3R3/FCER1G/TREM1/PTPN6/C1QA/CYBB/PIK3R1/C1QB/HCK/NCF1/ITGAM/NCKAP1L/NCF2 |
| 12 | WP49 | WP49 | IL-2 Signaling Pathway | 42 | -0.654594269333697 | -1.92105350035104 | 0.00227790432801822 | 0.0136986301369863 | 0.00729992790194665 | 3731 | tags=55%, list=15%, signal=46% | MAP2K1/MAPK3/CISH/FYN/SOCS3/CCND2/AKT1/IL2/CRKL/FOS/GRB2/STAT5B/JAK1/IL2RG/STAT3/STAT5A/PTK2B/MAPK1/PIK3R1/JUN/FOXO3/GAB2 |
| 13 | WP1539 | WP1539 | Angiogenesis | 24 | -0.732880961801299 | -1.89749435748104 | 0.00229357798165138 | 0.0136986301369863 | 0.00729992790194665 | 4385 | tags=62%, list=18%, signal=51% | FLT1/PDGFRA/TIMP2/MAPK14/AKT1/ARNT/KDR/MAPK1/FGFR2/TIMP3/TEK/FGF2/PDGFB/ANGPT1 |
| 14 | WP98 | WP98 | Prostaglandin Synthesis and Regulation | 45 | -0.67707967450932 | -2.02155511161406 | 0.00229885057471264 | 0.0136986301369863 | 0.00729992790194665 | 3864 | tags=60%, list=16%, signal=51% | PPARGC1B/EDNRA/ANXA2/ANXA4/PRL/TBXA2R/PTGIS/SCGB1A1/ABCC4/PTGER3/PTGFR/ANXA6/HSD11B1/PTGS1/HPGDS/HPGD/PTGER2/MITF/PTGIR/PTGER4/ANXA3/TBXAS1/PTGDS/PPARG/EDN1/EDNRB |
| 15 | WP4481 | WP4481 | Resistin as a regulator of inflammation | 33 | -0.728719111343713 | -2.03471110257775 | 0.00230414746543779 | 0.0136986301369863 | 0.00729992790194665 | 5951 | tags=67%, list=25%, signal=50% | IKBKG/PLCD3/PLCB4/AKT3/TNF/CHUK/RELA/PLCG1/MAPK3/MAPK14/NFKB1/PLCG2/AKT1/ITPR1/IL6/PLCD1/MAPK1/RETN/PLCE1/NFKBIA/PLCB2 |
| 16 | WP4149 | WP4149 | White fat cell differentiation | 32 | -0.717187214869053 | -1.99503493862868 | 0.0023094688221709 | 0.0136986301369863 | 0.00729992790194665 | 4991 | tags=75%, list=21%, signal=60% | EBF1/RORA/CEBPB/INS/TLE3/TCF7L1/CTNNA1/EGR2/NR3C1/STAT5B/KLF4/RARA/NR2F2/GATA3/ZNF423/STAT5A/FOXO1/CEBPD/KLF2/CEBPA/KLF15/GATA2/PPARG |
| 17 | WP3942 | WP3942 | PPAR signaling pathway | 67 | -0.635560220456832 | -2.05978992655891 | 0.00232558139534884 | 0.0136986301369863 | 0.00729992790194665 | 2954 | tags=37%, list=12%, signal=33% | CYP7A1/ACSL5/HMGCS2/ACAA1/PCK2/ACSL4/ILK/CPT1A/RXRA/SLC27A6/FABP1/APOA1/ACSL1/LPL/FABP3/SORBS1/ACADL/OLR1/PPARG/RXRG/FABP5/FABP4/CYP27A1/CD36 |
| 18 | WP4155 | WP4155 | Endometrial cancer | 63 | -0.670921336651483 | -2.1426216377604 | 0.00232558139534884 | 0.0136986301369863 | 0.00729992790194665 | 4412 | tags=46%, list=18%, signal=38% | DDB2/CCND1/PDPK1/RAF1/MAP2K1/MAPK3/TCF7L1/CTNNA3/CTNNB1/CTNNA1/APC/PTEN/SOS2/AKT1/CDKN1A/TCF7L2/FOS/GRB2/ARAF/ILK/PIK3R3/MAPK1/FGFR2/PIK3R1/FOXO3/FGF2/GADD45B/AXIN2 |
| 19 | WP2637 | WP2637 | Structural Pathway of Interleukin 1 (IL-1) | 49 | -0.644842291521501 | -1.94927613450899 | 0.00233100233100233 | 0.0136986301369863 | 0.00729992790194665 | 5196 | tags=55%, list=21%, signal=43% | MAP3K14/CHUK/RELA/MAPK10/TRAF6/MAP2K3/TAB1/MAP2K1/TAB2/MAPK3/MAP2K4/MAPK14/NFKB1/MAPK9/FOS/TOLLIP/MKNK1/MAP3K8/IL1R1/MKNK2/IL1A/MAPK1/MBP/NFKBIA/MYD88/MAP3K3 |
| 20 | WP286 | WP286 | IL-3 Signaling Pathway | 49 | -0.763650610847904 | -2.30841855504975 | 0.00233100233100233 | 0.0136986301369863 | 0.00729992790194665 | 3731 | tags=59%, list=15%, signal=50% | MAP2K1/MAPK3/FYN/YWHAB/CD86/AKT1/BCL2L1/CD69/INPP5D/CRKL/FOS/GRB2/CSF2RB/STAT5B/JAK1/VAV1/TGFB1/STAT3/STAT5A/PRKACA/PTPN6/RAPGEF1/MAPK1/PIK3R1/JUN/HCK/GAB2/IL3RA |
| 21 | WP4249 | WP4249 | Hedgehog Signaling Pathway | 43 | -0.655625827604928 | -1.92858111322179 | 0.00234192037470726 | 0.0136986301369863 | 0.00729992790194665 | 4544 | tags=42%, list=19%, signal=34% | SHH/CCND1/PTCH1/DHH/GPR161/CDON/CCND2/SUFU/EVC/FBXL17/SPOP/PRKACA/GRK3/ARRB2/LRP2/HHIP/ARRB1 |
| 22 | WP395 | WP395 | IL-4 Signaling Pathway | 54 | -0.658040267101942 | -2.01956684134443 | 0.00235849056603774 | 0.0136986301369863 | 0.00729992790194665 | 3558 | tags=52%, list=15%, signal=44% | MAPK14/SOCS3/NFKB1/FES/IL4R/EP300/AKT1/STAT6/INPP5D/FOS/GRB2/FLNA/STAT5B/JAK1/IRS1/NFIL3/GATA3/IL2RG/STAT3/STAT5A/PTPN6/MAPK1/NFKBIA/PIK3R1/GAB2/CEBPA/DOK2 |
| 23 | WP195 | WP195 | IL-1 signaling pathway | 55 | -0.64272055450148 | -1.98054641301281 | 0.00237529691211401 | 0.0136986301369863 | 0.00729992790194665 | 5196 | tags=56%, list=21%, signal=44% | NFKBIB/MAP3K14/CHUK/RELA/SQSTM1/TRAF6/PLCG1/MAP2K3/TAB1/MAP2K1/TAB2/MAPK3/MAP2K4/MAPK14/NFKB1/IL1B/AKT1/MAPK9/TOLLIP/IL1R1/IL1A/HSPB2/MAPK1/NFKBIA/IRAK3/PIK3R1/JUN/MYD88/MAP3K3/PRKCZ |
| 24 | WP2572 | WP2572 | Primary Focal Segmental Glomerulosclerosis FSGS | 72 | -0.564895810605214 | -1.85209517787765 | 0.00237529691211401 | 0.0136986301369863 | 0.00729992790194665 | 4385 | tags=49%, list=18%, signal=40% | CTSL/LRP6/VIM/NPHS2/CR1/CD151/CTNNB1/CDKN1B/FYN/MYH9/COL4A5/AKT1/DAG1/NOTCH1/CDKN1A/COL4A3/ITGA3/SCARB2/ACTN4/TGFB1/ILK/UTRN/PARVA/VCL/LAMB2/TLN1/MME/CDKN1C/PLCE1/PTPRO/TLR4/TRPC6/SYNPO/COL4A4 |
| 25 | WP2795 | WP2795 | Cardiac Hypertrophic Response | 55 | -0.562491502261919 | -1.73332021101943 | 0.00237529691211401 | 0.0136986301369863 | 0.00729992790194665 | 5125 | tags=53%, list=21%, signal=42% | RAC1/MAP3K14/CHUK/GSK3B/MAP4K1/MAP2K3/PDPK1/RAF1/MAP2K1/TNFRSF1A/MAPK3/NFATC2/MAP2K4/MAPK14/HDAC5/NFKB1/MAPK7/AKT1/MAP2K5/HDAC7/CALM1/TGFB1/MEF2A/MAPK1/FGFR2/PRKG1/FGF2/PRKD1 |
| 26 | WP560 | WP560 | TGF-beta Receptor Signaling | 55 | -0.618128504062653 | -1.90476589386786 | 0.00237529691211401 | 0.0136986301369863 | 0.00729992790194665 | 3558 | tags=47%, list=15%, signal=40% | RUNX3/CTNNB1/THBS1/ITGB6/NFKB1/FKBP1A/ZEB2/EP300/MAPK9/FOS/TFE3/JAK1/TGFB1/BMP4/SKI/STAT3/ZNF423/ZFYVE9/JUN/LEFTY2/SMAD7/ENG/TGFBR2/TGFBR3/SMAD6 |
| 27 | WP2203 | WP2203 | Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway | 47 | -0.678806935318986 | -2.03356014944586 | 0.00238095238095238 | 0.0136986301369863 | 0.00729992790194665 | 3758 | tags=51%, list=15%, signal=43% | MAP2K1/MAPK3/CISH/MAPK14/FYN/NFKB1/FES/AKT1/MAPK9/STAT6/STAT5B/JAK1/STAT3/IL6/STAT5A/TSLP/PI4K2A/MAPK1/NFKBIA/HCK/GAB2/IL7R/BTK |
| 28 | WP2034 | WP2034 | Leptin signaling pathway | 76 | -0.60032634434338 | -1.98738947622487 | 0.00239234449760766 | 0.0136986301369863 | 0.00729992790194665 | 5087 | tags=54%, list=21%, signal=43% | CHUK/JAK2/RELA/SP1/GSK3B/PLCG1/ACACA/CCND1/CFL2/RAF1/MAP2K1/MAPK3/CISH/MAPK14/PDE3B/FYN/SOCS3/NFKB1/IL1B/ROCK1/PTEN/ROCK2/PLCG2/AKT1/BCL2L1/RPS6KA1/GRB2/STAT5B/JAK1/IRS1/NCOA1/RHOA/STAT3/SOCS2/MAPK1/FOXO1/PIK3R1/PTPN1/ACACB/LEPR |
| 29 | WP2037 | WP2037 | Prolactin Signaling Pathway | 76 | -0.614835273428521 | -2.03542150621455 | 0.00239234449760766 | 0.0136986301369863 | 0.00729992790194665 | 3758 | tags=42%, list=15%, signal=36% | RAF1/MAP2K1/MAPK3/CISH/MAPK14/FYN/SOCS3/NFKB1/PRL/AKT1/MAPK9/FOS/GRB2/FLNA/STAT5B/JAK1/VAV1/IRS1/CTSD/STAT3/STAT5A/SOCS2/PTPN6/MAPK1/NFKBIA/PIK3R1/JUN/PTPN1/GAB2/SIRPA/RPS6KA2 |
| 30 | WP3945 | WP3945 | TYROBP Causal Network | 61 | -0.729451463583409 | -2.29761362489514 | 0.00239234449760766 | 0.0136986301369863 | 0.00729992790194665 | 3574 | tags=57%, list=15%, signal=49% | TYROBP/ELF4/PYCARD/RUNX3/GIMAP2/IL13RA1/ABCC4/ZFP36L2/RNASE6/CAPG/SH2B3/C3/PLEK/LYL1/RPS6KA1/NRROS/C1QC/ITGB2/SLC7A7/HCLS1/HLX/GAPT/STAT5A/CXCL16/FKBP15/IL10RA/CD4/APBB1IP/ITGAM/NCKAP1L/BIN2/ITGAX/NCF2/CD37 |
| 31 | WP304 | WP304 | Kit receptor signaling pathway | 59 | -0.701221359646638 | -2.18048350455823 | 0.00244498777506112 | 0.0136986301369863 | 0.00729992790194665 | 3758 | tags=51%, list=15%, signal=43% | RAF1/MAP2K1/MAPK3/DOK1/MAPK14/JUNB/FYN/EP300/AKT1/RPS6KA1/MATK/INPP5D/CRKL/FOS/GRB2/STAT5B/CRK/VAV1/STAT3/STAT5A/PRKCB/PTPN6/MAPK1/PIK3R1/FOXO3/MITF/GAB2/BTK/TBX2 |
| 32 | WP4341 | WP4341 | Non-genomic actions of 1,25 dihydroxyvitamin D3 | 71 | -0.655504539161554 | -2.13476766388158 | 0.00244498777506112 | 0.0136986301369863 | 0.00729992790194665 | 3689 | tags=46%, list=15%, signal=40% | MAPK3/ETS1/MAPK14/NFKB1/CD40/MAPK7/PLCG2/DEFB4A/MAPK9/CD40LG/JAK1/TLR2/IL6/CAMK2A/PRKCQ/RXRA/PRKCB/RSAD2/PLCD1/MAPK1/PLCE1/JUN/TLR8/PRKCZ/PRKCD/PLCB2/OAS2/TLR4/PRKCH/PRKCE/RXRG/CAV1 |
| 33 | WP4298 | WP4298 | Viral Acute Myocarditis | 84 | -0.639586276038619 | -2.14233412609757 | 0.00245700245700246 | 0.0136986301369863 | 0.00729992790194665 | 3558 | tags=50%, list=15%, signal=43% | MICA/EIF4G2/GSK3B/AIF1/CCND1/MAPK3/PYCARD/FYN/TLR5/AKT1/DAG1/SGCB/BCL2L1/CASP7/LAMA2/IL2/CD40LG/SGCD/JAK1/DMD/TLR3/RAC2/ITGB2/TGFB1/HLA-DMA/BNIP2/STAT3/IL6/CXCR4/CASP1/MAPK1/PIK3R1/CD4/NOS1/TLR4/ITGAL/PTCRA/SGCA/EDN1/SGCG/CAV1 |
| 34 | WP23 | WP23 | B Cell Receptor Signaling Pathway | 97 | -0.612444610670313 | -2.10875866219875 | 0.00246913580246914 | 0.0136986301369863 | 0.00729992790194665 | 3932 | tags=48%, list=16%, signal=41% | MAX/PDPK1/TEC/RAF1/MAP2K1/MEF2D/PTPRC/ETS1/NFATC2/PIK3AP1/MAPK14/PTPN18/FYN/NFKB1/PLCG2/GAB1/AKT1/PIP5K1C/MAPK9/BCL6/RPS6KA1/INPP5D/CRKL/GRB2/MAPK4/CRK/VAV1/RAC2/CD81/HCLS1/CAMK2A/PRKCB/NFATC3/PTPN6/RAPGEF1/MAPK1/FOXO1/NFKBIA/CD22/PIK3R1/JUN/KLF11/PRKCD/GAB2/BTK/PIP5K1B |
| 35 | WP2806 | WP2806 | Human Complement System | 97 | -0.642923121630133 | -2.21370174256498 | 0.00246913580246914 | 0.0136986301369863 | 0.00729992790194665 | 3341 | tags=44%, list=14%, signal=38% | THBS1/FGG/FGA/CD40/C2/SELL/C3/FCN1/ITGB2/ICAM1/TLR2/C4A/DCN/C3AR1/PRKACA/FCGR3A/ITGA2B/ARRB2/CD93/C7/APOA1/GNAI2/CFP/F11/WAS/C5/ICAM2/SELP/SFTPA1/SERPING1/CFD/C5AR1/SFTPA2/CLEC4M/LRP2/C4BPA/FPR1/VSIG4/SELPLG/ITGAX/MASP1/PROS1 |
| 36 | WP3931 | WP3931 | ESC Pluripotency Pathways | 117 | -0.483215380726575 | -1.72146078193607 | 0.00246913580246914 | 0.0136986301369863 | 0.00729992790194665 | 3823 | tags=36%, list=16%, signal=30% | RAF1/MAP2K1/PDGFRA/WNT2/CTNNB1/FZD1/APC/MAPK7/PTEN/GAB1/WNT7A/AKT1/MAP2K5/LIFR/PDGFA/FOS/GRB2/FGF18/JAK1/MAPK4/ARAF/FGF7/FZD7/BMP4/FGF10/FZD5/STAT3/BMPR1A/IL6ST/MAPK1/FGFR2/JUN/FZD4/SMAD7/FGFR4/BMPR2/FGF2/WNT3A/PDGFB/SMAD6/SELENOP |
| 37 | WP2431 | WP2431 | Spinal Cord Injury | 119 | -0.467420960589209 | -1.66836001096026 | 0.00247524752475248 | 0.0136986301369863 | 0.00729992790194665 | 3188 | tags=37%, list=13%, signal=32% | ROS1/IL1B/PDYN/FKBP1A/ROCK2/EGR1/FCGR2A/FCGR2C/PTPRA/CXCL2/IL2/BTG2/PLA2G5/FOS/MAG/GJA1/TGFB1/ICAM1/IL1R1/PLXNA2/RHOA/IL6/ZFP36/IL1A/MAPK1/RHOB/MBP/AQP1/C1QB/TNFSF13/C5/FOXO3/SELP/SEMA6A/NOS1/LILRB3/LOC102725035/BDNF/TLR4/AQP4/SLIT3/EFNB2/SLIT2 |
| 38 | WP366 | WP366 | TGF-beta Signaling Pathway | 132 | -0.478303442833193 | -1.73180872054833 | 0.00247524752475248 | 0.0136986301369863 | 0.00729992790194665 | 4442 | tags=45%, list=18%, signal=37% | SKP1/TRAF6/ZEB1/APP/RBL2/CCND1/MAP4K1/MAP2K3/TAB1/RAF1/MAP2K1/FOSB/YAP1/PRKAR2A/ETS1/LIMK2/MAP2K4/MAPK14/THBS1/JUNB/ATF3/FN1/PML/ROCK1/ZEB2/TGFB1I1/EP300/AKT1/DCP1A/KLF10/MAPK9/CDKN1A/FOS/JUND/GRB2/MAPK4/WWP1/TGFB1/SKI/RHOA/MEF2A/MAPK1/ZFYVE9/NEDD4L/SIK1/DAB2/PIAS1/PIK3R1/JUN/SPTBN1/KLF11/NEDD9/SMAD7/KLF6/CDKN2B/TGFBR2/TGFBR3/CAV1 |
| 39 | WP3915 | WP3915 | Angiopoietin Like Protein 8 Regulatory Pathway | 132 | -0.52741840164463 | -1.9096408379071 | 0.00247524752475248 | 0.0136986301369863 | 0.00729992790194665 | 4412 | tags=39%, list=18%, signal=32% | MAPKAP1/CAP1/MAP3K4/MLXIPL/INS/MAP4K1/MAP2K3/FASN/PDPK1/SCD/RAF1/MAP2K1/MAPK3/FLOT2/MAP2K4/MAPK14/SREBF2/RHOQ/PRKAB1/MAPK7/MAP3K11/CYP7A1/MINK1/TRIP10/SOS2/AKT1/MAP2K5/MAPK9/RPS6KA1/SHC3/MAPK4/CRK/IRS1/MAP4K2/MAP3K8/PIK3R3/PIK3C2G/RXRA/MAP3K6/RAPGEF1/THRB/MAPK1/FOXO1/THRA/PIK3R1/PTPN1/MAP3K3/FOXO3/LPL/RPS6KA2/FBP1 |
| 40 | WP1544 | WP1544 | MicroRNAs in cardiomyocyte hypertrophy | 98 | -0.544054587205048 | -1.87677876598414 | 0.00248138957816377 | 0.0136986301369863 | 0.00729992790194665 | 3906 | tags=39%, list=16%, signal=33% | MAP2K3/TAB1/PDPK1/RAF1/MAP2K1/MAPK3/CISH/CTNNB1/FZD1/MAP2K4/MAPK14/HDAC5/NFKB1/ROCK1/MAPK7/ROCK2/AKT1/MAP2K5/RCAN1/HDAC7/CALM1/MAPK4/TGFB1/PIK3R3/RHOA/STAT3/IL6ST/PRKCB/MAPK1/FGFR2/PIK3R1/PRKG1/MYLK/PLCB2/FGF2/WNT3A/EDN1 |
| 41 | WP236 | WP236 | Adipogenesis | 130 | -0.474985938357607 | -1.7171574020515 | 0.00248138957816377 | 0.0136986301369863 | 0.00729992790194665 | 3747 | tags=35%, list=15%, signal=30% | MEF2D/CNTFR/CTNNB1/FZD1/SOCS3/EGR2/PTGIS/LIFR/KLF7/STAT6/ID3/CDKN1A/PCK2/NR3C1/STAT5B/IRS1/TGFB1/WWTR1/RARA/BMP4/NCOA1/GATA3/STAT3/IL6/STAT5A/RXRA/BMP2/IL6ST/MEF2A/RETN/FOXO1/CEBPD/FRZB/CFD/PLIN2/LPL/CEBPA/KLF15/KLF6/GDF10/GATA2/GADD45B/PPARG/RXRG/EPAS1 |
| 42 | WP4540 | WP4540 | Pathways Regulating Hippo Signaling | 98 | -0.521323028062473 | -1.79836364272296 | 0.00248138957816377 | 0.0136986301369863 | 0.00729992790194665 | 3799 | tags=35%, list=16%, signal=29% | GNA11/PDGFRA/PRKAR2A/TCF7L1/CTNNB1/CSF1R/PRKAB1/CDH9/FLT4/TCF7L2/PRKAR1A/CDH6/CDH10/RHOA/PRKCQ/PRKACA/CDH19/PRKCB/KDR/NTRK2/FGFR2/GNAI2/PRKCZ/LATS2/PRKCD/CDH13/FGFR4/PLCB2/TEK/PRKCH/PRKCE/GNAQ/CDH5 |
| 43 | WP536 | WP536 | Calcium Regulation in the Cardiac Cell | 149 | -0.516859634478407 | -1.89197755115013 | 0.00248138957816377 | 0.0136986301369863 | 0.00729992790194665 | 3912 | tags=43%, list=16%, signal=36% | GNG5/RGS19/PRKAR2B/ADRB3/GNA11/PRKAR2A/YWHAH/ADCY5/ATP2B3/RGS16/CAMK1/YWHAB/FKBP1A/RGS18/CACNA1C/RYR1/GNG2/PKIA/CACNA1D/SLC8A1/RGS2/PLN/GJA4/PRKAR1A/CALM1/GJA1/ANXA6/GNAI1/ITPR1/CAMK2A/PRKCQ/PRKACA/RGS6/CASQ2/PRKCB/PKIG/ARRB2/CHRM1/ADCY4/GJC2/ADCY9/GNAI2/ATP1B2/PRKCZ/GNG7/ADRA1A/SLC8A3/PRKCD/GJA5/RGS5/PRKCH/CACNA1S/ARRB1/PRKCE/PRKD1/ADRA1B/GNAQ/CHRM2/RGS9/ADRB1/ADRB2/KCNJ5/GRK5 |
| 44 | WP138 | WP138 | Androgen receptor signaling pathway | 90 | -0.525276462659242 | -1.77249607836137 | 0.00249376558603491 | 0.0136986301369863 | 0.00729992790194665 | 5087 | tags=47%, list=21%, signal=37% | RAC1/RELA/TLE5/KAT7/SMAD4/SIN3A/SP1/SIRT1/GSK3B/NCOR2/RNF6/CCND1/KAT5/LIMK2/CTNNB1/ROCK1/PTEN/ROCK2/TGFB1I1/DSTN/EP300/AKT1/RNF14/CDKN1A/FLNA/NCOA1/RHOA/STAT3/KLK3/ZMIZ1/FOXO1/RHOB/PIAS1/PIK3R1/JUN/NCOA4/AR/KAT2B/ETV5/PLPP1/CAV1 |
| 45 | WP51 | WP51 | Regulation of Actin Cytoskeleton | 151 | -0.543185017975121 | -1.9920987618635 | 0.00249376558603491 | 0.0136986301369863 | 0.00729992790194665 | 3827 | tags=39%, list=16%, signal=33% | CFL2/RAF1/MAP2K1/PDGFRA/MAPK3/ARHGAP35/PIP4K2B/SSH1/ITGA1/TMSB4X/APC/FN1/PAK4/ROCK1/ROCK2/CYFIP2/PAK5/SOS2/PIP5K1C/PDGFA/RRAS2/SSH2/FGF18/IQGAP1/MAPK4/CRK/VAV1/RAC2/FGF7/DIAPH1/EZR/PIK3R3/FGF10/RHOA/GSN/PIK3C2G/WASF2/VCL/RDX/CHRM1/MAPK1/RRAS/FGFR2/MYL3/PIK3R1/PIK3R5/SLC9A1/WAS/MYLK/MSN/MRAS/FGFR4/ARHGEF6/MYH10/FGF2/PDGFB/CHRM2/PIP5K1B |
| 46 | WP69 | WP69 | T-Cell antigen Receptor (TCR) Signaling Pathway | 90 | -0.602333142752611 | -2.03251660657157 | 0.00249376558603491 | 0.0136986301369863 | 0.00729992790194665 | 5173 | tags=57%, list=21%, signal=45% | GRAP2/SKAP1/MAP3K14/CHUK/RELA/CD8A/TRAF6/PLCG1/ICOS/VIM/MAP4K1/CD3E/PDPK1/RAF1/MAP2K1/MAPK3/LCP2/NFATC2/MAPK14/DBNL/FYN/NFKB1/IL1B/AKT1/SH2B3/MAPK9/CRKL/FOS/GRB2/NFATC1/CD247/CRK/VAV1/TGFB1/MAP3K8/ITPR1/GATA3/IL6/PRKCQ/IL1A/PTK2B/MAPK1/NFKBIA/CD83/PIK3R1/JUN/WAS/PRKCD/CD4/GAB2 |
| 47 | WP4541 | WP4541 | Hippo-Merlin Signaling Dysregulation | 121 | -0.476114960490584 | -1.70282708999761 | 0.0025 | 0.0136986301369863 | 0.00729992790194665 | 3848 | tags=34%, list=16%, signal=29% | PRKAR2B/PDGFRA/PRKAR2A/CTNNB1/ITGA1/CTNNA1/ITGB6/CSF1R/PAK4/CDH9/PAK5/AJUBA/FLT4/PRKAR1A/CDH6/ITGA3/ITGB2/ITGA9/CDH10/PRKACA/ITGAE/CDH19/CCN2/SAV1/KDR/ITGA10/ITGA2B/NTRK2/CD44/FGFR2/LATS2/CDH13/FGFR4/ITGAM/TEK/PPP1R14A/ITGAL/ITGAX/ITGA8/CDH5 |
| 48 | WP231 | WP231 | TNF alpha Signaling Pathway | 92 | -0.508347384485388 | -1.72409999242593 | 0.00251256281407035 | 0.0136986301369863 | 0.00729992790194665 | 5196 | tags=41%, list=21%, signal=33% | TNF/RAC1/MAP3K14/CHUK/PYGL/PPP2CA/SKP1/RIPK3/RIPK1/MAP2K3/TAB1/RAF1/TNFRSF1A/TNFRSF1B/TAB2/MAPK3/NSMAF/MAP2K4/NFKB1/FBXW11/AKT1/OTUD7B/BCL2L1/CASP7/MAPK9/CFLAR/GRB2/MAP4K2/TNFAIP3/MAP3K8/IL6/GLUL/MAPK1/NFKBIA/JUN/MAP3K3/PRKCZ |
| 49 | WP185 | WP185 | Integrin-mediated Cell Adhesion | 102 | -0.583190075319158 | -2.02092896305995 | 0.00252525252525253 | 0.0136986301369863 | 0.00729992790194665 | 3848 | tags=52%, list=16%, signal=44% | ITGAD/MAPK10/DOCK1/CAPN9/PXN/CAPN3/VASP/ITGB7/MAP2K3/PDPK1/RAF1/MAP2K1/ITGA1/FYN/ITGB6/CAPN2/PAK4/ROCK1/MAPK7/ROCK2/CAPNS1/AKT1/MAP2K5/SHC3/GRB2/MAPK4/ARAF/CRK/RAP1A/ITGA3/RAC2/ITGB2/ILK/ITGA9/ZYX/ITGAE/VCL/RAPGEF1/ITGA10/ITGA2B/MAPK1/TLN1/CAV3/ITGAM/CAV2/SORBS1/ITGAL/ITGAX/TNS1/ITGA8/SELENOP/CAV1 |
| 50 | WP399 | WP399 | Wnt Signaling Pathway and Pluripotency | 102 | -0.50786031199826 | -1.75988868319521 | 0.00252525252525253 | 0.0136986301369863 | 0.00729992790194665 | 3454 | tags=37%, list=14%, signal=32% | TCF7L1/CTNNB1/FZD1/MAP2K4/CTNND1/APC/CCND2/EP300/WNT7A/MMP7/FBXW2/MAPK9/PPP2R5C/TCF7L2/LRRK2/FRAT1/PAFAH1B1/PPP2CB/FZD7/RHOA/FZD5/PRKCQ/PRKCB/CD44/JUN/PRKCZ/PRKCD/FZD4/LDLR/NKD2/CCND3/PRKCH/WNT3A/PRKCE/PRKD1/NKD1/AXIN2 |
| 51 | WP1449 | WP1449 | Regulation of toll-like receptor signaling pathway | 143 | -0.507378430442551 | -1.85054502255692 | 0.00253164556962025 | 0.0136986301369863 | 0.00729992790194665 | 5125 | tags=41%, list=21%, signal=33% | RAC1/CCL5/CHUK/RELA/TIRAP/SQSTM1/SYK/MAPK10/TRAF6/CCL4/OTUD5/IFNA14/RIPK1/MAP2K3/TAB1/MAP2K1/TAB2/MAPK3/CISH/TRAFD1/RNF41/TLR7/MAP2K4/MAPK14/NFKB1/IL1B/TLR5/CD40/CD86/AKT1/SFTPD/MAPK9/CTNNAL1/FOS/TLR3/TNFAIP3/TOLLIP/MAP3K8/TLR2/PIK3R3/PELI3/IRF5/IL6/TREM1/PTPN6/ZMYND11/MAPK1/NFKBIA/IRAK3/PIK3R1/PIK3R5/JUN/MYD88/TLR8/SFTPA2/BTK/TLR4/SMAD6 |
| 52 | WP35 | WP35 | G Protein Signaling Pathways | 94 | -0.589402590436537 | -2.00316087263184 | 0.00253164556962025 | 0.0136986301369863 | 0.00729992790194665 | 2550 | tags=40%, list=11%, signal=36% | PRKAR2B/GNA11/AKAP11/PRKAR2A/ADCY5/PDE4B/PDE8A/PRKAR1A/AKAP4/PDE4A/AKAP7/CALM1/PDE8B/GNAI1/ITPR1/RHOA/PPP3CC/PDE1C/PRKCQ/PRKACA/PRKCB/AKAP2/AKAP13/GNGT2/RRAS/ADCY4/ADCY9/GNAI2/PRKCZ/GNG7/SLC9A1/PRKCD/PDE1B/PRKCH/PRKCE/PRKD1/GNAQ |
| 53 | WP4217 | WP4217 | Ebola Virus Pathway on Host | 129 | -0.604719341351543 | -2.17244775160068 | 0.00253164556962025 | 0.0136986301369863 | 0.00729992790194665 | 4950 | tags=51%, list=20%, signal=41% | ITGA5/ACTB/NPC2/TIMD4/TPCN2/HLA-F/BST2/CLTB/ADAM17/CTSL/HLA-DQB1/EPS15/DDX58/ICAM3/RFC1/HLA-DOB/MAPK3/ITGA1/SOCS3/NFKB1/RAB7A/VPS18/FOLR1/TYRO3/HLA-DMB/CLEC6A/EP300/AKT1/VPS11/AXL/RAB5A/HLA-DRB5/CLEC10A/HLA-DRB1/FLNA/HAVCR2/IQGAP1/ITGA3/ACTN4/RAB9A/HLA-DRA/PIK3R3/HLA-DMA/VPS39/RHOA/GSN/HLA-DQA2/HLA-DQA1/ASGR1/HLA-DQB2/HLA-G/MAPK1/HLA-DPB1/RHOB/HLA-E/PIK3R1/DAB2IP/ICAM2/CAV3/CLEC4M/CAV2/TLR4/HLA-DPA1/HLA-DOA/CAV1 |
| 54 | WP4666 | WP4666 | Hepatitis B infection | 152 | -0.478187392186986 | -1.75338279172837 | 0.00253164556962025 | 0.0136986301369863 | 0.00729992790194665 | 5024 | tags=38%, list=21%, signal=30% | CHUK/JAK2/RELA/TIRAP/SMAD4/MAPK10/TRAF6/DDB2/MAVS/IFNA14/DDX58/MAP2K3/TAB1/RAF1/MAP2K1/TAB2/MAPK3/NFATC2/IFIH1/MAP2K4/DDX3X/MAPK14/TGFB2/YWHAB/NFKB1/EGR2/CASP10/SOS2/EP300/AKT1/MAPK9/STAT6/CDKN1A/FOS/GRB2/NFATC1/STAT5B/JAK1/ATP6AP1/ARAF/TLR3/TGFB1/TLR2/PIK3R3/STAT3/IL6/STAT5A/PRKCB/NFATC3/PTK2B/MAPK1/PIK3R1/JUN/MYD88/CASP12/TLR4/TGFBR2 |
| 55 | WP2380 | WP2380 | Brain-Derived Neurotrophic Factor (BDNF) signaling pathway | 144 | -0.521528155745828 | -1.89448800527984 | 0.00255754475703325 | 0.0136986301369863 | 0.00729992790194665 | 3762 | tags=38%, list=15%, signal=32% | RAF1/MAP2K1/MAPK3/CTNNB1/ALPL/MAPK14/CYFIP1/CAMK1/FYN/NFKB1/EGR2/APC/KCNN2/MAPK7/RHOG/EGR1/AKT1/MAP2K5/MAPK9/RPS6KA1/FOS/SHC3/GRB2/STAT5B/RAP1A/IRS1/KCNA3/KIDINS220/CDKL5/STAT3/CAMK2A/STAT5A/BMP2/PTK2B/MEF2A/NTRK3/MAPK1/NTRK2/NFKBIA/PIK3R1/JUN/ACACB/FOXO3/PRKCD/SIRPA/NCF1/BDNF/CNR1/NCF2/RASGRF1/SORT1/GRIA1/DPYSL2 |
| 56 | WP2355 | WP2355 | Corticotropin-releasing hormone signaling pathway | 93 | -0.531240232360081 | -1.79886540543531 | 0.00256410256410256 | 0.0136986301369863 | 0.00729992790194665 | 4685 | tags=48%, list=19%, signal=39% | GRK6/GSK3B/PLCG1/ACACA/CRHBP/FOSL2/POMC/RAF1/MAP2K1/GNA11/FOSB/MAPK3/TCF4/CTNNB1/MAPK14/JUNB/NFKB1/PLCG2/CRH/AKT1/ERN1/MAPK9/IL2/FOS/JUND/KRT1/GJA1/TGFB1/GNAI1/RHOA/CAMK2A/PRKCQ/RAPGEF3/PRKCB/GRK3/ARRB2/MAPK1/NFKBIA/GNAI2/PRKCD/CASP12/TLR4/ARRB1/GNAQ |
| 57 | WP306 | WP306 | Focal Adhesion | 198 | -0.518087693346908 | -1.9576602945688 | 0.00261780104712042 | 0.0136986301369863 | 0.00729992790194665 | 3848 | tags=37%, list=16%, signal=31% | PDPK1/RAF1/MAP2K1/PDGFRA/LAMC3/MAPK3/ARHGAP35/CTNNB1/ITGA1/THBS1/FYN/ITGB6/FN1/CAPN2/PAK4/CCND2/MYL12A/ROCK1/PTEN/ROCK2/AKT1/PIP5K1C/PDGFA/PPP1R12C/MAPK9/LAMA2/CRKL/SHC3/GRB2/FLNA/PARVB/CRK/RAP1A/VAV1/ITGA3/RAC2/ACTN4/ILK/ITGA9/DIAPH1/PIK3R3/RHOA/PARVA/ZYX/PRKCB/VCL/LAMB2/KDR/RAPGEF1/ITGA10/ITGA2B/MAPK1/TLN1/PIK3R1/JUN/TNXB/MYL9/HCK/LAMA3/MYLK/CAV3/CAV2/PARVG/CCND3/VWF/PDGFB/COL4A4/VEGFD/RASGRF1/FGR/ITGA8/CAV1 |
| 58 | WP481 | WP481 | Insulin Signaling | 160 | -0.558049183557073 | -2.05099522607501 | 0.00261780104712042 | 0.0136986301369863 | 0.00729992790194665 | 3932 | tags=38%, list=16%, signal=32% | PPP1R3A/MAP2K3/PDPK1/RAF1/MAP2K1/MAPK3/FLOT2/STXBP1/MAP2K4/MAPK14/SOCS3/TBC1D4/RHOQ/MAPK7/MAP3K11/PTEN/MINK1/EGR1/SOS2/GAB1/AKT1/MAP2K5/MAPK9/RPS6KA1/SNAP23/FOS/SHC3/GRB2/SGK3/MAPK4/CRK/RAC2/IRS1/MAP4K2/STXBP2/MAP3K8/PIK3R3/PIK3C2G/PRKCQ/MAP3K6/PRKCB/RAPGEF1/MAPK1/FOXO1/EHD1/PIK3R1/JUN/PTPN1/MYO1C/VAMP2/MAP3K3/PRKCZ/FOXO3/SGK1/PRKCD/SORBS1/PRKCH/RPS6KA2/EHD2/RHOJ |
| 59 | WP706 | WP706 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways | 160 | -0.402371045121336 | -1.47883218356196 | 0.00261780104712042 | 0.0136986301369863 | 0.00729992790194665 | 3799 | tags=32%, list=16%, signal=28% | PPARGC1B/TAC1/PRKAR2A/YWHAH/RUNX3/CTNNB1/SLC1A3/YWHAB/NFKB1/IL1B/MECP2/EGR1/CHRNA4/EP300/SSTR1/HADHB/PRKAR1A/NR3C1/KCNQ1/SLC25A4/GJA1/HADHA/C4A/TPPP/GATA3/CPT1A/IL6/PRKACA/PBX1/IL1A/C4B/THRB/NTRK2/JUN/SPTBN1/AR/TSPYL1/VAMP2/GPD1L/KCNJ8/FMO3/CAV3/BDNF/IL6R/SCN4B/AQP4/GATA2/VIPR1/CHRM2/MAOA/SLC6A4 |
| 60 | WP289 | WP289 | Myometrial Relaxation and Contraction Pathways | 156 | -0.495512547324554 | -1.8138804577885 | 0.00263157894736842 | 0.0136986301369863 | 0.00729992790194665 | 3857 | tags=39%, list=16%, signal=33% | RGS19/CNN2/PRKAR2B/ACTA2/PRKAR2A/YWHAH/ADCY5/MYL4/RGS16/GUCY1A1/YWHAB/NFKB1/IL1B/ATF3/RGS18/PLCG2/RYR1/GNG2/CRH/CNN1/PKIA/ETS2/PDE4B/SLC8A1/RGS2/FOS/PRKAR1A/MAFF/IGFBP1/CALM1/GJA1/ITPR1/IL6/CAMK2A/PRKCQ/PRKACA/RGS6/PRKCB/PKIG/PLCD1/ARRB2/ADCY4/JUN/ADCY9/PRKCZ/GNG7/PRKCD/NOS1/RGS5/PRKCH/ARRB1/PRKCE/GUCA2A/PRKD1/GNAQ/RXFP1/RGS9/RAMP2/RAMP3/GRK5 |
| 61 | WP3929 | WP3929 | Chemokine signaling pathway | 164 | -0.529961471137152 | -1.95216415864642 | 0.00263852242744063 | 0.0136986301369863 | 0.00729992790194665 | 2991 | tags=32%, list=12%, signal=29% | ROCK1/ROCK2/GNG2/SOS2/AKT1/CXCL12/CRKL/SHC3/GRB2/CCL24/STAT5B/CRK/RAP1A/VAV1/RAC2/PF4/GNAI1/PIK3R3/CCR1/STAT3/CXCR4/CXCL16/PRKCB/GNGT2/PTK2B/DOCK2/ARRB2/MAPK1/XCR1/ADCY4/NFKBIA/PIK3R1/PIK3R5/ADCY9/GNAI2/CXCR2/HCK/PRKCZ/GNG7/WAS/FOXO3/PRKCD/NCF1/CX3CL1/RASGRP2/ELMO1/PLCB2/ARRB1/CX3CR1/PREX1/FGR/GRK5 |
| 62 | WP437 | WP437 | EGF/EGFR Signaling Pathway | 163 | -0.567435392513956 | -2.08919690999873 | 0.00263852242744063 | 0.0136986301369863 | 0.00729992790194665 | 4418 | tags=42%, list=18%, signal=35% | PIK3C2B/PLCG1/AP2M1/MAP3K4/EPS15/MAP4K1/PDPK1/RAF1/MAP2K1/FOSB/MEF2D/LIMK2/STXBP1/PTPN12/MAPK14/STAM/RALBP1/ROCK1/MAPK7/PTEN/USP8/SOS2/GAB1/AKT1/MAP2K5/RAB5A/MAPK9/RPS6KA1/INPP5D/CRKL/FOS/JUND/GRB2/STAT5B/JAK1/IQGAP1/MAPK4/CRK/RAP1A/VAV1/GJA1/IQSEC1/PTPN5/STAT3/CAMK2A/STAT5A/SH3KBP1/PRKCB/PEBP1/PTK2B/MEF2A/MAPK1/FOXO1/SH3GL3/FOXO4/PLCE1/PIK3R1/JUN/MAP3K3/PRKCZ/PRKCD/SPRY2/GAB2/CAV2/DOK2/RPS6KA2/REPS2/CAV1 |
| 63 | WP4223 | WP4223 | Ras Signaling | 184 | -0.475218887563424 | -1.77943506956402 | 0.00268096514745308 | 0.0136986301369863 | 0.00729992790194665 | 3925 | tags=35%, list=16%, signal=30% | GNG5/RAF1/MAP2K1/PDGFRA/STK4/MAPK3/PLA2G4E/PLA2G4D/ETS1/PLA2G3/SHOC2/NFKB1/RALBP1/CSF1R/PAK4/PLA1A/PLCG2/GNG2/PAK5/SOS2/RGL1/GAB1/AKT1/ETS2/RAB5A/RRAS2/BCL2L1/MAPK9/FLT4/PLA2G5/SHC3/GRB2/PLAAT3/CALM1/RAP1A/RAC2/PIK3R3/RHOA/PRKACA/PRKCB/KDR/GNGT2/PLA2G4C/RAPGEF5/RAB5B/MAPK1/RRAS/NTRK2/FGFR2/FOXO4/PLCE1/PIK3R1/GNG7/GAB2/MRAS/FGFR4/RASGRP2/RASSF5/PLA2G12B/RASGRP4/TEK/PLA2G4F/PLA2G1B/RASGRF1 |
| 64 | WP3888 | WP3888 | VEGFA-VEGFR2 Signaling Pathway | 236 | -0.589062517396146 | -2.26327859348876 | 0.00271739130434783 | 0.0136986301369863 | 0.00729992790194665 | 3823 | tags=40%, list=16%, signal=34% | CAMKK2/PDPK1/RAF1/MAP2K1/F3/ELOA/MAPK3/DOK1/ETS1/NFATC2/CTNNB1/MAP2K4/CTNNA1/MAPK14/HDAC5/STAM/OCLN/FGG/FYN/MYH9/NFKB1/FGA/CTNND1/CAPN2/ROCK1/PTPRJ/ROCK2/EGR1/SHB/FBXW11/GAB1/AKT1/RAB11A/ERN1/HBEGF/RCAN1/SLC8A1/RAB5A/HDAC7/BCL2L1/MAPK9/STAT6/PLA2G5/SOD2/GRB2/NFATC1/IQGAP1/CRK/RAP1A/GJA1/ICAM1/MKNK1/EZR/RHOA/PTPN9/ADAMTS1/STAT3/PRKCB/CCN2/VCL/PTPN6/KDR/RAPGEF1/PTK2B/ARRB2/MAPK1/FOXO1/FOXO4/NFKBIA/PIK3R1/JUN/PTPN1/PRKG1/TNXB/SMARCA2/ACACB/PRKCZ/FOXO3/PRKCD/ERG/NCF1/ARHGEF15/NOTCH4/MMRN2/PRKCE/PRKD1/RCAN2/RHOJ/TXNIP/NCF2/CDH5/KL/CAV1 |
| 65 | WP382 | WP382 | MAPK Signaling Pathway | 246 | -0.489721566933744 | -1.8914958861666 | 0.00273972602739726 | 0.0136986301369863 | 0.00729992790194665 | 3932 | tags=36%, list=16%, signal=31% | MAX/MAPKAPK3/PPP5D1/MAP2K3/TAB1/CACNG2/RAF1/MAP2K1/TNFRSF1A/STK4/TAB2/MAPK3/PLA2G4E/PLA2G4D/MAP2K4/PPM1B/MAPK14/TGFB2/CACNG4/NFKB1/IL1B/TAOK3/MAPK7/MAP3K11/CACNA1C/TAOK2/SOS2/AKT1/MAP2K5/CACNA1D/PDGFA/CACNB4/RRAS2/RAPGEF2/MAPK9/CACNA2D2/CRKL/FOS/LRRK2/JUND/GRB2/FLNA/NFATC1/FGF18/ARAF/CRK/RAP1A/RAC2/DUSP7/MAP4K2/FGF7/TGFB1/MKNK1/MAP3K8/DUSP16/IL1R1/FGF10/PTPN5/PPP3CC/PRKACA/MAP3K6/MKNK2/NFATC3/IL1A/PLA2G4C/DUSP3/ARRB2/MAPK1/RRAS/NTRK2/FGFR2/JUN/HSPA2/PRKCD/DUSP6/MRAS/FGFR4/BDNF/RASGRP2/DUSP1/RASGRP4/PLA2G4F/FGF2/CACNA1S/PDGFB/ARRB1/TGFBR2/RASGRF1 |
| 66 | WP3959 | WP3959 | DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM | 55 | 0.582197440322824 | 1.76019258020718 | 0.00344234079173838 | 0.0169469085131736 | 0.00903091835241487 | 6494 | tags=45%, list=27%, signal=33% | CDKN2A/CDC25C/CHEK1/EXO1/FANCD2/BRCA1/RAD51/BLM/BRCA2/CASP3/PRKDC/H2AFX/CHEK2/ACTL6A/E2F1/PCNA/ATM/MRE11/RIF1/PARP1/ATR/RAD9A/TP73/RAD52/CDK5 |
| 67 | WP45 | WP45 | G1 to S cell cycle control | 64 | 0.556928674132859 | 1.71459626479989 | 0.00350877192982456 | 0.0170122275385433 | 0.00906572651725006 | 4697 | tags=48%, list=19%, signal=39% | CDKN2A/POLE2/CCNB1/ORC6/MCM4/CDK1/CDC45/CCNE2/ORC1/TFDP1/MCM2/CCNE1/CDC25A/E2F2/MCM6/MYT1/PRIM2/CREB3L4/POLE/E2F3/MCM7/CDKN2C/RPA3/WEE1/PRIM1/GADD45A/E2F1/ORC2/PCNA/ATM/MCM3 |
| 68 | WP3965 | WP3965 | Lipid Metabolism Pathway | 29 | -0.644170593288779 | -1.7565770866349 | 0.00451467268623025 | 0.0184997832056656 | 0.00985843710301915 | 4413 | tags=48%, list=18%, signal=40% | PRKACB/BCKDHA/ACACA/PRKAR2B/FASN/PRKAR2A/PNPLA2/PRKAB1/AKT1/PRKAR1A/PRKACA/ACSS2/ABHD5 |
| 69 | WP3972 | WP3972 | PDGFR-beta pathway | 29 | -0.703598072588881 | -1.91862880017568 | 0.00451467268623025 | 0.0184997832056656 | 0.00985843710301915 | 5099 | tags=59%, list=21%, signal=46% | JAK2/PLCG1/RAF1/MAP2K1/MAPK3/MAP2K4/STAT6/FOS/GRB2/STAT5B/JAK1/STAT3/STAT5A/PRKCB/PIK3R1/JUN |
| 70 | WP2526 | WP2526 | PDGF Pathway | 40 | -0.612454490672276 | -1.78473542851409 | 0.00454545454545455 | 0.0184997832056656 | 0.00985843710301915 | 5099 | tags=52%, list=21%, signal=42% | RAC1/CHUK/PLCG1/RAF1/MAP2K1/MAPK3/MAP2K4/NFKB1/PDGFA/FOS/GRB2/JAK1/VAV1/RHOA/STAT3/MAPK1/NFKBIA/PIK3R1/JUN/PDGFB |
| 71 | WP3298 | WP3298 | Melatonin metabolism and effects | 38 | -0.627506056973278 | -1.81250107551413 | 0.00455580865603645 | 0.0184997832056656 | 0.00985843710301915 | 4443 | tags=53%, list=18%, signal=43% | TRAF6/GSK3B/MAP2/CYP1B1/CYP1A1/NFKB1/PER3/CRY1/APOE/CALM1/SULT1A1/CAMK2A/PER1/FOXO1/CRY2/CYP1A2/MAOA/EDN1/ADRB1 |
| 72 | WP143 | WP143 | Fatty Acid Beta Oxidation | 34 | -0.643312671618906 | -1.80765765982521 | 0.0045662100456621 | 0.0184997832056656 | 0.00985843710301915 | 3837 | tags=44%, list=16%, signal=37% | ACADS/ACAT1/PNPLA2/ACSL5/HADHB/ACSL4/HADHA/CPT1A/SLC25A20/DECR1/ACSS2/ACSL1/LPL/ACADL |
| 73 | WP2197 | WP2197 | Endothelin Pathways | 34 | -0.610275753893501 | -1.71482653738974 | 0.0045662100456621 | 0.0184997832056656 | 0.00985843710301915 | 3731 | tags=47%, list=15%, signal=40% | MAP2K1/EDNRA/CNN1/NPY1R/CALM1/GNAI1/NPY/MAPK1/ADRA1A/MYLK/PTGIR/CALCRL/EDN1/ADRB1/EDNRB |
| 74 | WP313 | WP313 | Signaling of Hepatocyte Growth Factor Receptor | 34 | -0.634577940990779 | -1.78311375851093 | 0.0045662100456621 | 0.0184997832056656 | 0.00985843710301915 | 4542 | tags=56%, list=19%, signal=45% | PXN/MAP4K1/RAF1/MAP2K1/MAPK3/ITGA1/PTEN/GAB1/CRKL/FOS/GRB2/CRK/RAP1A/STAT3/RAPGEF1/PTK2B/MAPK1/JUN |
| 75 | WP422 | WP422 | MAPK Cascade | 33 | -0.670850003116976 | -1.87313043977875 | 0.00460829493087558 | 0.0184997832056656 | 0.00985843710301915 | 4622 | tags=48%, list=19%, signal=39% | MAP2/MAP2K3/RAF1/MAP2K1/MAPK3/MAP2K4/MAPK14/SOS2/GRB2/ARAF/MAPK1/RRAS/MBP/JUN/MAP3K3 |
| 76 | WP2324 | WP2324 | AGE/RAGE pathway | 66 | -0.612892706020922 | -1.97297630344254 | 0.00464037122969838 | 0.0184997832056656 | 0.00985843710301915 | 3731 | tags=56%, list=15%, signal=48% | CHUK/JAK2/RELA/TIRAP/SP1/INS/RAF1/MAP2K1/MAPK3/ALPL/MAPK14/NFKB1/ROCK1/AKT1/MMP7/MAPK9/STAT5B/IRS1/DIAPH1/EZR/RHOA/STAT3/STAT5A/PRKCB/MAPK1/FOXO1/FOXO4/NFKBIA/JUN/MYD88/PRKCZ/PRKCD/MSN/NCF1/MSR1/AGER |
| 77 | WP2374 | WP2374 | Oncostatin M Signaling Pathway | 65 | -0.597863939945069 | -1.91873157520145 | 0.00465116279069767 | 0.0184997832056656 | 0.00985843710301915 | 3731 | tags=49%, list=15%, signal=42% | MAP2K1/MAPK3/MAPK14/CDKN1B/JUNB/SOCS3/NFKB1/EGR1/AKT1/LIFR/CASP7/MAPK9/FOS/JUND/GRB2/STAT5B/JAK1/IRS1/CCN1/STAT3/IL6ST/PRKCB/PTK2B/MAPK1/NFKBIA/PIK3R1/TIMP3/PRKCD/LDLR/PRKCH/PRKCE |
| 78 | WP2849 | WP2849 | Hematopoietic Stem Cell Differentiation | 63 | -0.597628338095296 | -1.90855669448911 | 0.00465116279069767 | 0.0184997832056656 | 0.00985843710301915 | 3661 | tags=48%, list=15%, signal=41% | MXI1/GYPA/CSF1/NFATC2/IL1B/CIITA/IKZF1/NOTCH1/LYL1/FOS/ZNF835/VAV1/IRF5/IL6/CXCR4/STAT5A/CSF3/GATA1/GP9/IL1A/ITGA2B/THRB/CD34/TNXB/FLI1/LMO2/NCKAP1L/SPI1/GATA2 |
| 79 | WP364 | WP364 | IL-6 signaling pathway | 43 | -0.601223554064732 | -1.76855203436559 | 0.00468384074941452 | 0.0184997832056656 | 0.00985843710301915 | 3728 | tags=47%, list=15%, signal=39% | MAPK3/MAP2K4/JUNB/SOCS3/GAB1/AKT1/BCL2L1/GRB2/JAK1/VAV1/NCOA1/STAT3/IL6/IL6ST/MAPK1/PIK3R1/HCK/PRKCD/IL6R |
| 80 | WP3303 | WP3303 | RAC1/PAK1/p38/MMP2 Pathway | 68 | -0.568156096046623 | -1.84262663906128 | 0.00472813238770686 | 0.0184997832056656 | 0.00985843710301915 | 3580 | tags=38%, list=15%, signal=33% | MAPK3/CTNNB1/TNIP1/MAPK14/NFKB1/FN1/ANGPTL1/AKT1/CASP7/MAPK9/GRB2/STAT5B/CRK/STAT3/STAT5A/MAPK1/FOXO1/NFKBIA/PIK3R1/NOS1/TEK/DOK2/RS1/ANGPT4/ANGPT1 |
| 81 | WP1541 | WP1541 | Energy Metabolism | 47 | -0.56738906134756 | -1.69977606938516 | 0.00476190476190476 | 0.0184997832056656 | 0.00985843710301915 | 5054 | tags=34%, list=21%, signal=27% | CAMK2G/SIRT1/GSK3B/PPARGC1B/MEF2D/MAPK14/PRKAB1/EP300/NCOA1/PPP3CC/RXRA/MEF2A/FOXO1/FOXO3/PPARG |
| 82 | WP1982 | WP1982 | Sterol Regulatory Element-Binding Proteins (SREBP) signalling | 71 | -0.575739856062364 | -1.87499972021835 | 0.00488997555012225 | 0.0184997832056656 | 0.00985843710301915 | 4836 | tags=41%, list=20%, signal=33% | ACSS1/SP1/SCAP/SIRT1/ACACA/INS/FDFT1/PPARGC1B/FASN/SCD/MED15/IDI1/SREBF2/PRKAB1/NR1H2/LSS/INSIG1/AKT1/GPAM/SAR1A/CYP51A1/HMGCS1/PRKACA/HMGCR/LDLR/LPL/RBP4/PPARG |
| 83 | WP4205 | WP4205 | MET in type 1 papillary renal cell carcinoma | 59 | -0.549954819803464 | -1.71011250062039 | 0.00488997555012225 | 0.0184997832056656 | 0.00985843710301915 | 4385 | tags=42%, list=18%, signal=35% | C8orf34/RAF1/MAP2K1/ELOA/MAPK3/ETS1/PAK4/PAK5/SOS2/GAB1/AKT1/CDKN1A/CRKL/GRB2/TFE3/ARAF/CRK/RAP1A/PIK3R3/STAT3/RAPGEF1/MAPK1/PIK3R1/JUN |
| 84 | WP4538 | WP4538 | Regulatory circuits of the STAT3 signaling pathway | 78 | -0.533002986817774 | -1.76304079571372 | 0.00488997555012225 | 0.0184997832056656 | 0.00985843710301915 | 3960 | tags=41%, list=16%, signal=34% | CTF1/PDGFRA/CNTFR/PTPRC/MAPK3/PTPRD/MAPK14/SOCS3/MAPK7/LIFR/IL11RA/MAPK9/CSF2RB/JAK1/MAPK4/CSF3R/IL2RG/STAT3/IL6ST/PRKCB/IL10RA/AGTR2/MAPK1/GHR/IFNLR1/IL3RA/IL20RA/IL7R/IL6R/F2RL3/AGTR1 |
| 85 | WP428 | WP428 | Wnt Signaling | 115 | -0.460205606485278 | -1.63752085375515 | 0.00490196078431373 | 0.0184997832056656 | 0.00985843710301915 | 5162 | tags=42%, list=21%, signal=33% | FZD8/RAC1/PPP3CB/CAMK2G/CHD8/WNT2B/GSK3B/LRP6/CCND1/DAAM1/NOTUM/SOST/WNT2/TCF7L1/NFATC2/CTNNB1/FZD1/APC/CCND2/ROCK2/WNT7A/SFRP5/MAPK9/TCF7L2/NFATC1/FRAT1/FZD7/CTNNBIP1/RHOA/FZD5/PPP3CC/CAMK2A/ROR1/DKK2/PRKCB/NFATC3/PRICKLE1/GPC4/DAAM2/JUN/SOX17/PLCB2/NKD2/CCND3/PRICKLE2/WNT3A/NKD1 |
| 86 | WP4321 | WP4321 | Thermogenesis | 108 | -0.472966706268173 | -1.66119186812598 | 0.00491400491400491 | 0.0184997832056656 | 0.00985843710301915 | 3860 | tags=28%, list=16%, signal=23% | MAP2K3/ADRB3/ARID1A/ADCY5/SMARCD3/PNPLA2/MAPK14/PRKAB1/SOS2/ACSL5/PRDM16/RPS6KA1/GRB2/ACSL4/CPT1A/SLC25A20/KLB/PRKACA/ADCY4/ADCY9/PRKG1/SMARCA2/ACSL1/MGLL/RPS6KA2/CNR1/PPARG/PRKG2/NPR1 |
| 87 | WP673 | WP673 | ErbB Signaling Pathway | 91 | -0.50746055745121 | -1.71751967058708 | 0.005 | 0.0186046511627907 | 0.00991432068543452 | 4412 | tags=37%, list=18%, signal=31% | GSK3B/PLCG1/CCND1/RAF1/MAP2K1/MAPK3/MAP2K4/CDKN1B/PAK4/PLCG2/PAK5/SOS2/GAB1/AKT1/HBEGF/ERBB4/MAPK9/CDKN1A/CRKL/SHC3/GRB2/STAT5B/ARAF/CRK/PIK3R3/CAMK2A/STAT5A/PRKCB/MAPK1/FOXO1/PIK3R1/JUN/NRG3 |
| 88 | WP26 | WP26 | Signal Transduction of S1P Receptor | 25 | -0.682006331746115 | -1.78248631708789 | 0.00683371298405467 | 0.0241545893719807 | 0.0128718535469108 | 3558 | tags=48%, list=15%, signal=41% | S1PR2/MAPK7/AKT1/MAPK4/GNAI1/S1PR5/MAPK1/ASAH1/GNAI2/PLCB2/S1PR1 |
| 89 | WP465 | WP465 | Tryptophan metabolism | 42 | -0.568462525644927 | -1.66828060658117 | 0.00683371298405467 | 0.0241545893719807 | 0.0128718535469108 | 4138 | tags=40%, list=17%, signal=34% | ACAT1/CYP1A1/ALDH3A2/ALDH1A1/WARS/IDO1/HAAO/ALDH2/OGDH/ALDH1A2/DHCR24/AOX1/CYP1A2/CAT/MAOB/INMT |
| 90 | WP4496 | WP4496 | Signal transduction through IL1R | 33 | -0.607456486490543 | -1.69612466333712 | 0.00691244239631336 | 0.0241545893719807 | 0.0128718535469108 | 5125 | tags=61%, list=21%, signal=48% | MAP3K14/CHUK/RELA/TRAF6/MAP2K3/TAB1/MAPK14/TGFB2/NFKB1/IL1B/TGFB1/TOLLIP/IL1R1/IL6/IL1A/NFKBIA/IRAK3/JUN/MYD88 |
| 91 | WP363 | WP363 | Wnt Signaling Pathway | 51 | -0.558895422142045 | -1.70696125777929 | 0.00696055684454756 | 0.0241545893719807 | 0.0128718535469108 | 3489 | tags=43%, list=14%, signal=37% | LRP6/CCND1/TCF4/NFATC2/CTNNB1/APC/AKT1/MAPK9/TCF7L2/FRAT1/GJA1/RHOA/ROR1/PI4K2A/PRKCB/ARRB2/MAPK1/TEK/PIP5K1B/AXIN2/PPARG |
| 92 | WP3680 | WP3680 | Association Between Physico-Chemical Features and Toxicity Associated Pathways | 66 | -0.493591530412936 | -1.58893128196474 | 0.00696055684454756 | 0.0241545893719807 | 0.0128718535469108 | 4412 | tags=42%, list=18%, signal=35% | PLCG1/DAAM1/RAF1/MAP2K1/CTNNB1/FZD1/MAP2K4/TMSB4X/CAMK1/CDKN1B/APC/FN1/ROCK2/AKT1/ERBB4/CDKN1A/GRB2/FZD7/RHOA/FZD5/STAT5A/MAPK1/JUN/MYLK/FZD4/NOS1/GRIA1 |
| 93 | WP2525 | WP2525 | Trans-sulfuration and one carbon metabolism | 31 | 0.619974131511702 | 1.66092493808102 | 0.00706713780918728 | 0.0241545893719807 | 0.0128718535469108 | 5937 | tags=55%, list=24%, signal=41% | DNMT3B/PSAT1/GCLC/TYMS/GCLM/MTHFD2L/CTH/PSPH/MTHFD2/BHMT/DHFR/SHMT2/DNMT3A/MAT1A/DNMT3L/CBS/DNMT1 |
| 94 | WP585 | WP585 | Interferon type I signaling pathways | 54 | -0.512799005748204 | -1.5738123030745 | 0.00707547169811321 | 0.0241545893719807 | 0.0128718535469108 | 3823 | tags=33%, list=16%, signal=28% | PTPRC/MAPK14/FYN/SOCS3/CRKL/JAK1/CRK/RAP1A/VAV1/IRS1/STAT3/STAT5A/PTPN6/RAPGEF1/PIAS1/PIK3R1/GAB2 |
| 95 | WP4534 | WP4534 | Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms | 47 | -0.553002892571109 | -1.65667818984855 | 0.00714285714285714 | 0.0241545893719807 | 0.0128718535469108 | 4886 | tags=43%, list=20%, signal=34% | ACTC1/TEAD1/TEAD4/MAPK10/TEAD3/MAP4K1/ITGB7/ACTA2/CTNNB1/CTNNA1/ITGB6/PAK4/PAK5/MAPK9/MAP4K2/ITGB2/SAV1/LIMD1/SGMS1 |
| 96 | WP61 | WP61 | Notch Signaling Pathway | 61 | -0.50872642550276 | -1.60237771110551 | 0.00717703349282297 | 0.0241545893719807 | 0.0128718535469108 | 5901 | tags=51%, list=24%, signal=39% | NCOR1/HEY2/SNW1/MAML2/PSEN2/DLL4/JAK2/NCSTN/SKP1/ADAM17/GSK3B/NCOR2/NOTCH2/CCND1/NFKB1/PSEN1/EP300/AKT1/NOTCH1/CDKN1A/GATA3/CIR1/STAT3/HEY1/NUMB/PIK3R1/APH1B/NOTCH4/PTCRA/FHL1 |
| 97 | WP558 | WP558 | Complement and Coagulation Cascades | 58 | -0.517764904303038 | -1.60778753824715 | 0.0072463768115942 | 0.0241545893719807 | 0.0128718535469108 | 1588 | tags=34%, list=7%, signal=32% | C3/C1QC/C3AR1/SERPINF2/SERPINA1/C1QA/C4B/THBD/C7/F8/C1QB/SERPIND1/SERPING1/CFD/C5AR1/VWF/MASP1/PROS1/CPB2 |
| 98 | WP710 | WP710 | DNA Damage Response (only ATM dependent) | 111 | -0.421948465844916 | -1.4909399130155 | 0.00738916256157635 | 0.0243642454697731 | 0.0129835781779712 | 3454 | tags=32%, list=14%, signal=27% | TCF7L1/CTNNB1/CDKN1B/NFKB1/APC/CCND2/PTEN/SOS2/WNT7A/AKT1/MAPK9/BCL6/PPP2R5C/CDKN1A/TCF7L2/PCK2/SOD2/GRB2/FRAT1/RAC2/IRS1/TGFB1/PIK3R3/RHOA/PIK3C2G/MAPK1/PIK3R1/PIK3R5/JUN/FOXO3/LDLR/CCND3/WNT3A/CAT |
| 99 | WP15 | WP15 | Selenium Micronutrient Network | 89 | -0.463322668064958 | -1.55866650168236 | 0.00753768844221105 | 0.0243642454697731 | 0.0129835781779712 | 3493 | tags=31%, list=14%, signal=27% | GGTLC1/FGG/NFKB1/IL1B/ABCA1/FGA/SELENON/SERPINA3/SOD2/DIO3/ICAM1/PTGS1/IL6/KMO/ALOX15B/GGTLC2/ALOX5AP/APOA1/GGT1/LDLR/SOD3/HBB/GPX3/HBA1/CAT/ALOX5/SELENOP |
| 100 | WP2328 | WP2328 | Allograft Rejection | 89 | -0.499394293978949 | -1.68001526971948 | 0.00753768844221105 | 0.0243642454697731 | 0.0129835781779712 | 3134 | tags=40%, list=13%, signal=35% | CD40/C2/HLA-DMB/CD86/C3/CXCL12/HLA-DRB5/CASP7/IL2/HLA-DRB1/CD40LG/LRRK2/C1QC/TGFB1/C8B/HLA-DRA/C4A/HLA-DMA/HLA-DQA2/HLA-DQA1/PECR/IL1A/C1QA/C4B/HLA-G/HLA-DPB1/C7/HLA-E/C1QB/PRKCZ/C5/PRF1/HLA-DPA1/HLA-DOA/AGTR1 |
| 101 | WP75 | WP75 | Toll-like Receptor Signaling Pathway | 103 | -0.47066931532722 | -1.62692638985206 | 0.00775193798449612 | 0.0248062015503876 | 0.013219094247246 | 5196 | tags=42%, list=21%, signal=33% | TNF/RAC1/CCL5/CHUK/RELA/TIRAP/MAPK10/TRAF6/CCL4/IFNA14/RIPK1/MAP2K3/TAB1/MAP2K1/TAB2/MAPK3/TLR7/MAP2K4/MAPK14/NFKB1/IL1B/TLR5/CD40/CD86/AKT1/MAPK9/FOS/TLR3/TOLLIP/MAP3K8/TLR2/PIK3R3/IRF5/IL6/MAPK1/NFKBIA/PIK3R1/PIK3R5/JUN/MYD88/TLR8/TLR4 |
| 102 | WP3858 | WP3858 | Toll-like Receptor Signaling | 31 | -0.593909181131908 | -1.64129979980801 | 0.00917431192660551 | 0.0286225402504472 | 0.0152528010545146 | 5024 | tags=45%, list=21%, signal=36% | RELA/TIRAP/TRAF6/TLR7/NFKB1/TLR5/TLR3/TOLLIP/TLR2/MAPK1/MYD88/TLR8/TLR4 |
| 103 | WP244 | WP244 | Alpha 6 Beta 4 signaling pathway | 33 | -0.592696115235935 | -1.65491112741854 | 0.00921658986175115 | 0.0286225402504472 | 0.0152528010545146 | 3558 | tags=39%, list=15%, signal=34% | MAPK14/GAB1/AKT1/LAMA2/GRB2/IRS1/RHOA/LAMB2/MAPK1/PIK3R1/LAMA3/PRKCD |
| 104 | WP2112 | WP2112 | IL17 signaling pathway | 32 | -0.600847580208362 | -1.67140725664644 | 0.0092378752886836 | 0.0286225402504472 | 0.0152528010545146 | 5196 | tags=66%, list=21%, signal=52% | IL17B/MAP3K14/JAK2/RELA/IL17RB/SP1/TRAF6/GSK3B/CEBPB/IL17RE/MAPK3/NFKB1/TRAF3IP2/AKT1/JAK1/STAT3/MAPK1/CEBPD/IL17RA/IL17D |
| 105 | WP410 | WP410 | Exercise-induced Circadian Regulation | 48 | -0.541562832478487 | -1.63667859285653 | 0.00930232558139535 | 0.0286225402504472 | 0.0152528010545146 | 3570 | tags=46%, list=15%, signal=39% | ARNTL/EIF4G2/CEBPB/TAB2/IDI1/TOB1/GSTM3/CRY1/GFRA1/BTG1/DAZAP2/PPP2CB/QKI/HLA-DMA/RBPMS/PER1/NCOA4/CRY2/PPP1R3C/CLDN5/KLF9 |
| 106 | WP2118 | WP2118 | Arrhythmogenic Right Ventricular Cardiomyopathy | 74 | -0.477962319992754 | -1.57337705473479 | 0.00952380952380952 | 0.0290249433106576 | 0.0154672395273899 | 3848 | tags=42%, list=16%, signal=35% | CACNG2/TCF7L1/CTNNA3/CTNNB1/ITGA1/CTNNA1/CACNG4/ITGB6/CACNA1C/CACNA1D/CACNB4/SLC8A1/DAG1/SGCB/LAMA2/CACNA2D2/TCF7L2/SGCD/DMD/ITGA3/ACTN4/GJA1/ITGA9/ITGA10/ITGA2B/ACTN2/CACNA1S/SGCA/SGCG/ITGA8 |
| 107 | WP2261 | WP2261 | Signaling Pathways in Glioblastoma | 82 | -0.46980885475768 | -1.56855575596006 | 0.00995024875621891 | 0.0300384868112269 | 0.0160073515244038 | 3823 | tags=40%, list=16%, signal=34% | PDPK1/RAF1/MAP2K1/PDGFRA/MAPK3/MAP2K4/CDKN1B/CCND2/PTEN/PLCG2/EP300/GAB1/AKT1/MAP2K5/CDKN1A/GRB2/ARAF/IRS1/PIK3C2G/PRKCQ/PRKCB/MAPK1/FOXO1/FGFR2/FOXO4/PIK3R1/PRKCZ/FOXO3/PRKCD/SPRY2/PRKCH/CDKN2B |
| 108 | WP4263 | WP4263 | Pancreatic adenocarcinoma pathway | 89 | -0.448736434831178 | -1.50959686901757 | 0.0100502512562814 | 0.0300568261870098 | 0.0160171244812355 | 3731 | tags=39%, list=15%, signal=33% | RAC1/CHUK/RELA/SMAD4/MAPK10/DDB2/CCND1/RAF1/MAP2K1/MAPK3/TGFB2/NFKB1/RALBP1/PAK4/PAK5/AKT1/BCL2L1/MAPK9/CDKN1A/JAK1/ARAF/RAC2/TGFB1/PIK3R3/RHOA/STAT3/PEBP1/MAPK1/PIK3R1/PRKCD/DUSP6/ARHGEF6/GADD45B/TGFBR2 |
| 109 | WP1433 | WP1433 | Nucleotide-binding Oligomerization Domain (NOD) pathway | 41 | -0.540170731284649 | -1.57711241728712 | 0.0114678899082569 | 0.033822348116518 | 0.0180237512989339 | 5235 | tags=46%, list=22%, signal=36% | CARD8/RAC1/CHUK/RELA/NLRP12/NLRP3/NOD2/PYCARD/IL1B/CASP5/CASP7/CARD9/MEFV/CASP1/NOD1/NFKBIA/CARD6/NLRC4 |
| 110 | WP3676 | WP3676 | BDNF-TrkB Signaling | 33 | -0.57433990094298 | -1.60365736936312 | 0.0115207373271889 | 0.033822348116518 | 0.0180237512989339 | 2738 | tags=42%, list=11%, signal=38% | TRPC3/MAP2K1/GAB1/AKT1/RPS6KA1/GRB2/MKNK1/MAPK1/NTRK2/GAB2/BDNF/ARC/TRPC6 |
| 111 | WP4396 | WP4396 | Nonalcoholic fatty liver disease | 155 | -0.362936694457218 | -1.32971578290757 | 0.0129533678756477 | 0.0376825247291569 | 0.0200808190990902 | 3164 | tags=15%, list=13%, signal=14% | NFKB1/IL1B/PRKAB1/MAP3K11/AKT1/ERN1/CASP7/MAPK9/IRS1/TGFB1/PIK3R3/COX7A1/IL6/RXRA/IL1A/ADIPOR2/PIK3R1/JUN/SMAD7/CEBPA/IL6R/COX4I2/LEPR |
| 112 | WP167 | WP167 | Eicosanoid Synthesis | 26 | -0.634788780537419 | -1.6851790590273 | 0.0136363636363636 | 0.0387174833635814 | 0.0206323431082243 | 3378 | tags=46%, list=14%, signal=40% | PTGIS/PLA2G5/PTGS1/ALOX15B/GGTLC2/ALOX5AP/GGT1/LTA4H/TBXAS1/PTGDS/ALOX5 |
| 113 | WP205 | WP205 | IL-7 Signaling Pathway | 25 | -0.647064231955439 | -1.69116192335721 | 0.0136674259681093 | 0.0387174833635814 | 0.0206323431082243 | 4412 | tags=68%, list=18%, signal=56% | CCND1/MAP2K1/MAPK3/CDKN1B/FYN/AKT1/BCL2L1/STAT5B/JAK1/IL2RG/STAT3/STAT5A/PTK2B/MAPK1/PIK3R1/IL7R |
| 114 | WP2586 | WP2586 | Aryl Hydrocarbon Receptor | 45 | -0.518898697111699 | -1.54927455814743 | 0.0137931034482759 | 0.0387174833635814 | 0.0206323431082243 | 4322 | tags=40%, list=18%, signal=33% | CYP1B1/CYP1A1/RAF1/MAP2K1/NFE2L2/CDKN1B/NFKB1/EP300/CDKN1A/ARNT/HPGDS/MAPK1/PLAGL1/LPL/KLF6/CYP1A2/CD36 |
| 115 | WP268 | WP268 | Notch Signaling | 45 | -0.517665468318334 | -1.54559250998549 | 0.0137931034482759 | 0.0387174833635814 | 0.0206323431082243 | 2384 | tags=24%, list=10%, signal=22% | NOTCH1/DTX4/NUMB/APH1B/INPP5K/KAT2B/NOTCH4/PTCRA/MFNG/KCNJ5 |
| 116 | WP3863 | WP3863 | T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection | 62 | -0.472479499049397 | -1.4986947424136 | 0.013986013986014 | 0.0389176041349954 | 0.0207389864140436 | 5125 | tags=48%, list=21%, signal=38% | MAP3K14/CHUK/CD8A/GSK3B/PLCG1/ICOS/RAF1/MAP2K1/PTPRC/MAPK3/LCP2/NFATC2/FYN/NFKB1/CHP1/AKT1/MAPK9/IL2/FOS/CD40LG/GRB2/CALM1/MAP3K8/PRKCQ/PTPN6/RRAS/NFKBIA/JUN/CD4 |
| 117 | WP24 | WP24 | Peptide GPCRs | 75 | -0.45329305494355 | -1.49817386341742 | 0.014218009478673 | 0.0392220951135807 | 0.0209012480539476 | 3865 | tags=35%, list=16%, signal=29% | NPY4R/HCRTR2/EDNRA/ATP8A1/GALR1/FPR3/SSTR1/NPY1R/GHSR/ACKR1/C3AR1/CCR1/CXCR4/CXCR1/AGTR2/AVPR2/CXCR2/TACR3/C5AR1/FPR1/SSTR4/FPR2/CX3CR1/AGTR1/EDNRB |
| 118 | WP176 | WP176 | Folate Metabolism | 70 | -0.464337196191892 | -1.50408010089958 | 0.0146699266503667 | 0.0401228763086954 | 0.0213812696118706 | 3592 | tags=37%, list=15%, signal=32% | INS/MTHFS/CSF1/FOLR3/FGG/NFKB1/IL1B/ABCA1/FGA/FOLR1/FOLR2/IL2/SERPINA3/SOD2/SLC19A1/ICAM1/IL6/APOA1/LDLR/NOS1/SOD3/HBB/GPX3/HBA1/CAT |
| 119 | WP2858 | WP2858 | Ectoderm Differentiation | 141 | -0.369997509624108 | -1.34987838598429 | 0.0151133501259446 | 0.040985356273748 | 0.0218408806458789 | 3453 | tags=27%, list=14%, signal=23% | CTNNB1/ARHGEF9/BCAS3/SNCA/GAS2L1/FYN/PI4KA/MECP2/CDON/SERPINB6/ABCC4/GLB1/ZBTB16/NFATC1/CDH6/DMD/ZNF219/BMP4/TSC22D1/PGM1/EDA/PLXNA2/NR2F2/FZD5/PLCXD3/BMPR1A/SOCS2/RAB8B/FGFR2/PTPRB/PTPN13/FZD4/SPRY2/CTNND2/SDCBP/GATA6/LDB2 |
| 120 | WP1528 | WP1528 | Physiological and Pathological Hypertrophy of the Heart | 25 | -0.634959122979062 | -1.6595241069428 | 0.0159453302961276 | 0.0427046263345196 | 0.0227570706124742 | 3906 | tags=56%, list=16%, signal=47% | MAP2K3/MAPK14/LIFR/FOS/CALM1/RHOA/STAT3/IL6ST/PRKCB/MAPK1/JUN/PRKCE/EDN1 |
| 121 | WP2516 | WP2516 | ATM Signaling Pathway | 40 | 0.554957330191489 | 1.55676315483946 | 0.0160142348754448 | 0.0427046263345196 | 0.0227570706124742 | 4611 | tags=42%, list=19%, signal=34% | CDC25C/CCNB1/CHEK1/CDK1/FANCD2/BRCA1/RAD51/CCNE1/CDC25A/MDM4/H2AFX/CHEK2/PIDD1/AP3B2/GADD45A/ATM/MRE11 |
| 122 | WP4216 | WP4216 | Chromosomal and microsatellite instability in colorectal cancer | 73 | -0.454120807285491 | -1.48751379329662 | 0.0169491525423729 | 0.0448242050707382 | 0.0238865829653276 | 4776 | tags=42%, list=20%, signal=34% | RAC1/SMAD4/MAPK10/GSK3B/DDB2/CCND1/RAF1/MAP2K1/MLH1/MAPK3/TCF7L1/CTNNB1/TGFB2/APC/AKT1/MAPK9/APPL1/CDKN1A/TCF7L2/FOS/ARAF/RAC2/TGFB1/RHOA/MAPK1/JUN/DCC/GADD45B/AXIN2/TGFBR2 |
| 123 | WP2036 | WP2036 | TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway | 42 | -0.514025556221922 | -1.50852312693655 | 0.0182232346241458 | 0.0473512873631252 | 0.0252332518185075 | 5196 | tags=55%, list=21%, signal=43% | TNF/RAC1/CCL5/MAP3K14/CHUK/RELA/GSK3B/TRIM63/RIPK1/RAF1/MAPK3/CTNNB1/MAPK14/NFKB1/AKT1/CASP7/MAPK9/IL6/TNFSF12/MAPK1/NFKBIA/JUN |
| 124 | WP3594 | WP3594 | Circadian rhythm related genes | 200 | -0.350218594169658 | -1.32383047067144 | 0.0182767624020888 | 0.0473512873631252 | 0.0252332518185075 | 3897 | tags=26%, list=16%, signal=22% | OPRL1/DYRK1A/ADORA2A/ID2/GNA11/HCRTR2/NAGLU/NKX2-1/RORB/PER3/PML/PTEN/CST3/ROCK2/EGR1/FBXW11/CRH/EP300/BTBD9/CRY1/KLF10/MAPK9/ID3/OPN3/JUND/NFIL3/UBC/HNF1B/ARNT/FBXL3/CPT1A/CARTPT/IL6/ARNT2/SFTPC/NTRK3/AGRP/CHRM1/PER1/SIK1/JUN/HEBP1/CRY2/PRF1/BHLHE41/GNAQ/PTGDS/PPARG/ID4/KLF9/PRKG2/SLC6A4 |
| 125 | WP430 | WP430 | Statin Pathway | 31 | -0.557914902741278 | -1.54182768556289 | 0.018348623853211 | 0.0473512873631252 | 0.0252332518185075 | 3115 | tags=39%, list=13%, signal=34% | ABCA1/APOA5/CYP7A1/APOE/CETP/HMGCR/LRP1/APOC1/APOA1/LDLR/LPL |
| 126 | WP4535 | WP4535 | Envelope proteins and their potential roles in EDMD physiopathology | 46 | -0.505460594276532 | -1.5219902451176 | 0.0186046511627907 | 0.0476279069767442 | 0.0253806609547124 | 5515 | tags=43%, list=23%, signal=34% | PLEC/SRF/ADCY3/SMAD4/ADCY8/MAP2K1/MAPK3/ADCY5/TGFB2/TMEM43/SOS2/GRB2/TGFB1/RHOA/CCN2/MAPK1/ADCY4/SYNE3/ADCY9 |