Gladstone-Bioinformatics-Workshop/statistics-enrichment-analysis/bladder_cancer_WikiPathways_rSEA.csv

1	set_id	name	ID	Name	Size	Coverage	TDP.bound	TDP.estimate	SC.adjP	Comp.adjP
2	WP1600	Nicotine Metabolism	38	WP1600	6	0.17	1	1	3.39506009152496e-24	3.39506009152496e-24
3	WP2276	Glial Cell Differentiation	88	WP2276	8	0.62	0.4	0.4	7.83386153710323e-26	5.70447887867626e-23
4	WP4030	SCFA and skeletal muscle substrate metabolism	332	WP4030	6	0.33	0.5	0.5	7.99040804992212e-20	7.99040804992212e-20
5	WP334	GPCRs, Class B Secretin-like	210	WP334	24	0.17	0.5	0.5	3.06579274689702e-21	1.60955895014834e-18
6	WP1991	SRF and miRs in Smooth Muscle Differentiation and Proliferation	60	WP1991	13	0.69	0.888888888888889	1	5.37258163429194e-24	1.16900918682e-14
7	WP206	Fatty Acid Omega Oxidation	76	WP206	15	0.33	0.6	0.8	2.94021006969881e-38	1.31928124608757e-14
8	WP3299	let-7 inhibition of ES cell reprogramming	205	WP3299	15	0.33	0.6	0.6	1.69191698398203e-15	1.74501293167954e-14
9	WP2023	Cell Differentiation - Index expanded	66	WP2023	50	0.22	0.727272727272727	0.727272727272727	4.7856489956754e-16	2.33586928012365e-14
10	WP2029	Cell Differentiation - Index	67	WP2029	42	0.14	0.833333333333333	0.833333333333333	4.7856489956754e-16	2.33586928012365e-14
11	WP2366	Butyrate-induced histone acetylation	105	WP2366	2	1	0.5	0.5	1.10524321914212e-13	1.10524321914212e-13
12	WP3297	EV release from cardiac cells and their functional effects	203	WP3297	9	0.44	0.75	0.75	3.05550468161626e-32	3.37870774082303e-13
13	WP554	ACE Inhibitor Pathway	530	WP554	17	0.65	0.545454545454545	0.545454545454545	3.79036700534385e-25	5.54255202240522e-13
14	WP4284	Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer	385	WP4284	5	0.4	0.5	0.5	2.90591396510707e-11	2.90591396510707e-11
15	WP2361	Gastric Cancer Network 1	103	WP2361	29	0.76	0.727272727272727	0.727272727272727	3.61848623532521e-17	1.04514067941364e-10
16	WP3944	Serotonin and anxiety-related events	309	WP3944	13	0.46	0.666666666666667	0.666666666666667	1.45750470372243e-17	3.26510400891469e-09
17	WP3947	Serotonin and anxiety	311	WP3947	17	0.41	0.428571428571429	0.428571428571429	1.45750470372243e-17	3.26510400891469e-09
18	WP1438	Influenza A virus infection	20	WP1438	2	0.5	1	1	1.28737203377495e-08	1.28737203377495e-08
19	WP383	Striated Muscle Contraction Pathway	265	WP383	38	0.61	0.565217391304348	0.652173913043478	1.03667354058147e-21	1.30607861950122e-08
20	WP2542	Sulindac Metabolic Pathway	133	WP2542	5	0.8	0.5	0.75	4.35964063989166e-11	2.5564111779557e-08
21	WP4222	Phosphodiesterases in neuronal function	366	WP4222	55	0.56	0.419354838709677	0.483870967741935	1.11151548949677e-22	3.51064709129753e-08
22	WP2943	Hypoxia-mediated EMT and Stemness	191	WP2943	2	1	0.5	0.5	1.87433487284931e-07	1.87433487284931e-07
23	WP2874	Liver X Receptor Pathway	175	WP2874	10	0.5	0.4	0.4	9.83107916736652e-08	2.35055233649832e-07
24	WP466	DNA Replication	480	WP466	42	0.98	0.634146341463415	0.75609756097561	3.91911842678923e-14	4.20885218710584e-07
25	WP545	Complement Activation	528	WP545	22	0.68	0.466666666666667	0.466666666666667	3.75341311013175e-54	6.35126956702113e-07
26	WP4240	Regulation of sister chromatid separation at the metaphase-anaphase transition	374	WP4240	16	0.94	0.533333333333333	0.533333333333333	4.41152154021936e-12	6.65380602412947e-07
27	WP4300	Extracellular vesicles in the crosstalk of cardiac cells	395	WP4300	28	0.61	0.411764705882353	0.588235294117647	1.55030261832076e-25	8.80494600850642e-07
28	WP531	DNA Mismatch Repair	525	WP531	22	0.95	0.523809523809524	0.571428571428571	3.57124737003596e-13	1.25145166671192e-06
29	WP4589	Major receptors targeted by epinephrine and norepinephrine	471	WP4589	15	0.73	0.636363636363636	0.636363636363636	1.11151548949677e-22	2.66815064645758e-06
30	WP4760	PKC-gamma calcium signaling pathway in ataxia	508	WP4760	22	0.55	0.416666666666667	0.583333333333333	6.52294438984146e-17	2.70719651941471e-06
31	WP4191	Caloric restriction and aging	354	WP4191	8	1	0.375	0.375	2.9447393377517e-11	3.80469322236512e-06
32	WP2446	Retinoblastoma Gene in Cancer	117	WP2446	88	0.98	0.546511627906977	0.593023255813954	1.96366351804733e-14	4.24785596200959e-06
33	WP1992	Genes targeted by miRNAs in adipocytes	61	WP1992	19	0.53	0.5	0.5	2.33586928012365e-14	8.49856030430427e-06
34	WP4337	ncRNAs involved in STAT3 signaling in hepatocellular carcinoma	406	WP4337	17	0.76	0.538461538461538	0.615384615384615	1.55030261832076e-25	9.36831691097847e-06
35	WP2645	Heroin metabolism	145	WP2645	3	0.67	0.5	1	1.87627142351219e-05	1.87627142351219e-05
36	WP2826	Cocaine metabolism	158	WP2826	4	0.5	0.5	1	1.87627142351219e-05	1.87627142351219e-05
37	WP1602	Nicotine Activity on Dopaminergic Neurons	40	WP1602	22	0.5	0.636363636363636	0.818181818181818	2.50026382158374e-16	2.24952453555091e-05
38	WP4545	Oxysterols derived from cholesterol	452	WP4545	18	0.56	0.6	0.6	1.46780086933461e-09	2.36116814219851e-05
39	WP45	G1 to S cell cycle control	430	WP45	64	0.95	0.491803278688525	0.573770491803279	3.91911842678923e-14	2.89588011644963e-05
40	WP1495	Glycine Metabolism	24	WP1495	4	0.75	0.666666666666667	0.666666666666667	7.32732034249336e-10	2.91348117795513e-05
41	WP2879	Farnesoid X Receptor Pathway	180	WP2879	19	0.37	0.428571428571429	0.428571428571429	1.03671457774015e-11	0.000129931976156264
42	WP34	Ovarian Infertility Genes	211	WP34	32	0.53	0.411764705882353	0.411764705882353	8.1728342950092e-20	0.000152471085336278
43	WP516	Hypertrophy Model	519	WP516	20	0.75	0.466666666666667	0.533333333333333	1.73723649603814e-29	0.000166791537749366
44	WP247	Small Ligand GPCRs	121	WP247	19	0.53	0.6	0.8	3.77273931182897e-18	0.000182717661150266
45	WP2363	Gastric Cancer Network 2	104	WP2363	33	0.88	0.448275862068966	0.448275862068966	1.12863099668653e-15	0.000185246692246443
46	WP170	Nuclear Receptors	44	WP170	39	0.74	0.413793103448276	0.413793103448276	5.53853655041636e-45	0.000204208460415242
47	WP3996	Ethanol effects on histone modifications	325	WP3996	31	0.9	0.428571428571429	0.5	2.94021006969881e-38	0.000238758692258098
48	WP4400	FABP4 in ovarian cancer	417	WP4400	2	0.5	1	1	0.000245357066905715	0.000245357066905715
49	WP58	Monoamine GPCRs	534	WP58	33	0.15	0.6	0.6	2.66815064645758e-06	0.000266280491622695
50	WP3679	Cell-type Dependent Selectivity of CCK2R Signaling	261	WP3679	13	0.69	0.444444444444444	0.555555555555556	6.52294438984146e-17	0.000315427333264674
51	WP2338	miRNA Biogenesis	99	WP2338	8	0.75	0.5	0.5	5.52094234656009e-11	0.000633704399420972
52	WP1455	Serotonin Transporter Activity	22	WP1455	11	0.73	0.375	0.5	5.50097841431123e-07	0.000698192443745329
53	WP4016	DNA IR-damage and cellular response via ATR	329	WP4016	83	0.9	0.413333333333333	0.466666666666667	3.1984443894539e-16	0.000704575375419051
54	WP179	Cell Cycle	48	WP179	122	0.94	0.434782608695652	0.48695652173913	3.91911842678923e-14	0.000860192369254168
55	WP2848	Differentiation Pathway	162	WP2848	48	0.54	0.461538461538462	0.538461538461538	1.55030261832076e-25	0.000900218402911242
56	WP2815	Mammary gland development pathway - Involution (Stage 4 of 4)	155	WP2815	10	1	0.5	0.7	3.47598200773578e-10	0.000979886474579196
57	WP322	Osteoblast Signaling	199	WP322	14	0.5	0.428571428571429	0.428571428571429	1.60955895014834e-18	0.00122105800992755
58	WP4583	Biomarkers for urea cycle disorders	467	WP4583	12	0.67	0.375	0.375	1.05891161032475e-42	0.00125836568297114
59	WP3893	Development and heterogeneity of the ILC family	289	WP3893	32	0.56	0.5	0.555555555555556	1.55030261832076e-25	0.00137922281926359
60	WP2406	Cardiac Progenitor Differentiation	112	WP2406	53	0.57	0.466666666666667	0.5	5.00019440781505e-25	0.0019450999028179
61	WP558	Complement and Coagulation Cascades	531	WP558	59	0.66	0.41025641025641	0.487179487179487	3.75341311013175e-54	0.00204133415581446
62	WP2516	ATM Signaling Pathway	127	WP2516	40	0.92	0.405405405405405	0.459459459459459	6.96540853859659e-18	0.00226170199642674
63	WP3876	BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation	282	WP3876	13	0.85	0.454545454545455	0.454545454545455	1.1219536394885e-16	0.00287452439577986
64	WP1545	miRNAs involved in DNA damage response	33	WP1545	50	0.28	0.357142857142857	0.428571428571429	1.33825325438479e-13	0.00291300857028192
65	WP3591	Sleep regulation	223	WP3591	38	0.34	0.461538461538462	0.538461538461538	1.55030261832076e-25	0.00298637777295038
66	WP2855	Dopaminergic Neurogenesis	166	WP2855	30	0.33	0.4	0.6	8.1921343985721e-23	0.00300186445388684
67	WP497	Urea cycle and metabolism of amino groups	515	WP497	21	0.76	0.375	0.4375	1.21134935033961e-14	0.00350987947486594
68	WP3407	FTO Obesity Variant Mechanism	212	WP3407	8	0.88	0.428571428571429	0.428571428571429	2.9447393377517e-11	0.00376777148807062
69	WP289	Myometrial Relaxation and Contraction Pathways	186	WP289	158	0.76	0.391666666666667	0.466666666666667	4.72920713559152e-27	0.00465022180500277
70	WP1530	miRNA Regulation of DNA Damage Response	27	WP1530	93	0.69	0.375	0.453125	2.50026382158374e-16	0.00482551043459127
71	WP4149	White fat cell differentiation	344	WP4149	33	0.91	0.4	0.433333333333333	3.05550468161626e-32	0.00497520122591071
72	WP2814	Mammary gland development pathway - Puberty (Stage 2 of 4)	154	WP2814	13	0.92	0.5	0.5	8.1728342950092e-20	0.00569300599773054
73	WP1603	Nicotine Activity on Chromaffin Cells	41	WP1603	4	0.25	1	1	0.00581825930604642	0.00581825930604642
74	WP4698	Vitamin D-sensitive calcium signaling in depression	486	WP4698	41	0.54	0.363636363636364	0.5	6.52294438984146e-17	0.00581825930604642
75	WP1971	Integrated Cancer Pathway	56	WP1971	46	0.93	0.372093023255814	0.418604651162791	1.47590569356761e-12	0.00623426422936051
76	WP4224	Purine metabolism and related disorders	368	WP4224	22	0.86	0.368421052631579	0.421052631578947	3.39506009152496e-24	0.00660624701596271
77	WP4259	Disorders of Folate Metabolism and Transport	379	WP4259	13	0.85	0.454545454545455	0.454545454545455	7.32732034249336e-10	0.00660624701596271
78	WP1601	Fluoropyrimidine Activity	39	WP1601	34	0.82	0.392857142857143	0.5	7.38854762906026e-09	0.00668550277003425
79	WP2806	Human Complement System	152	WP2806	99	0.64	0.349206349206349	0.428571428571429	3.75341311013175e-54	0.00703640980157322
80	WP707	DNA Damage Response	557	WP707	69	0.9	0.370967741935484	0.451612903225806	2.50026382158374e-16	0.00934439177317729
81	WP2895	Differentiation of white and brown adipocyte	187	WP2895	25	0.72	0.388888888888889	0.388888888888889	4.791051754563e-15	0.00971361957709086
82	WP1995	Effects of Nitric Oxide	62	WP1995	8	0.5	0.5	0.75	3.39506009152496e-24	0.0112147264561884
83	WP136	Phase I biotransformations, non P450	10	WP136	8	0.62	0.4	0.6	1.87627142351219e-05	0.0123569322150726
84	WP536	Calcium Regulation in the Cardiac Cell	527	WP536	152	0.7	0.355140186915888	0.429906542056075	7.92756655687513e-25	0.0169432049684982
85	WP35	G Protein Signaling Pathways	216	WP35	97	0.78	0.355263157894737	0.434210526315789	1.11151548949677e-22	0.0169866528793556
86	WP241	One Carbon Metabolism	113	WP241	31	0.81	0.4	0.48	7.32732034249336e-10	0.0170103318686093
87	WP4571	Urea cycle and related diseases	464	WP4571	9	0.67	0.5	0.5	6.0595781921859e-07	0.020635406510022
88	WP4752	Base Excision Repair	503	WP4752	31	0.97	0.4	0.466666666666667	3.57124737003596e-13	0.0220340720140378
89	WP4720	Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway	491	WP4720	9	0.44	0.5	0.5	4.43345799464762e-09	0.0230432320025256
90	WP474	Endochondral Ossification	498	WP474	65	0.83	0.351851851851852	0.462962962962963	4.81536487673321e-20	0.0246820506324245
91	WP3875	ATR Signaling	281	WP3875	9	0.89	0.375	0.375	4.60260415203756e-08	0.0248929712443472
92	WP3959	DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM	314	WP3959	55	0.95	0.346153846153846	0.423076923076923	2.50026382158374e-16	0.0248929712443472
93	WP4560	MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement	458	WP4560	18	0.94	0.411764705882353	0.470588235294118	6.52294438984146e-17	0.0254612754912739
94	WP2525	Trans-sulfuration and one carbon metabolism	128	WP2525	32	0.88	0.357142857142857	0.464285714285714	7.32732034249336e-10	0.0321645449138761
95	WP98	Prostaglandin Synthesis and Regulation	568	WP98	45	0.82	0.378378378378378	0.459459459459459	2.17394413943821e-22	0.0332806226599994
96	WP4304	Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS	397	WP4304	31	0.52	0.375	0.375	7.83386153710323e-26	0.0344632354643189
97	WP3599	Transcription factor regulation in adipogenesis	228	WP3599	22	0.86	0.368421052631579	0.368421052631579	1.55030261832076e-25	0.0362388400314306
98	WP1604	Codeine and Morphine Metabolism	42	WP1604	15	0.27	0.5	0.5	6.49286728094462e-06	0.0372370714105519
99	WP236	Adipogenesis	102	WP236	131	0.79	0.346153846153846	0.413461538461538	3.75341311013175e-54	0.0373548404617312
100	WP4661	Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension)	481	WP4661	6	0.33	0.5	0.5	0.0431468886224066	0.0431468886224066
101	WP3585	Cytosine methylation	222	WP3585	9	0.89	0.375	0.5	7.49087453817701e-07	0.046146524101977
102	WP3872	Regulation of Apoptosis by Parathyroid Hormone-related Protein	279	WP3872	22	0.91	0.35	0.45	1.28737203377495e-08	0.0485074090657223
103	WP4399	MicroRNA network associated with chronic lymphocytic leukemia	416	WP4399	7	0.57	0.5	0.5	1.28737203377495e-08	0.0485074090657223
104	WP53	ID signaling pathway	523	WP53	16	0.81	0.307692307692308	0.384615384615385	1.33825325438479e-13	0.0542788662751285
105	WP734	Serotonin Receptor 4/6/7 and NR3C Signaling	564	WP734	19	0.84	0.3125	0.375	1.69191698398203e-15	0.0542788662751285
106	WP2881	Estrogen Receptor Pathway	182	WP2881	13	0.77	0.3	0.4	2.58938282317479e-38	0.0594386193019534
107	WP3963	Mevalonate pathway	315	WP3963	7	1	0.285714285714286	0.428571428571429	0.00314781622146767	0.0618737980244723
108	WP2197	Endothelin Pathways	81	WP2197	34	0.68	0.304347826086957	0.391304347826087	4.72920713559152e-27	0.0668243064530906
109	WP2355	Corticotropin-releasing hormone signaling pathway	100	WP2355	93	0.78	0.328767123287671	0.410958904109589	5.53853655041636e-45	0.0668243064530906
110	WP727	Monoamine Transport	561	WP727	32	0.53	0.294117647058824	0.529411764705882	4.62070637396041e-12	0.0730490654877152
111	WP167	Eicosanoid Synthesis	43	WP167	27	0.67	0.333333333333333	0.388888888888889	2.17394413943821e-22	0.0735098081465718
112	WP3624	Lung fibrosis	235	WP3624	63	0.67	0.30952380952381	0.428571428571429	1.55030261832076e-25	0.080115977530217
113	WP4584	Biomarkers for pyrimidine metabolism disorders	468	WP4584	15	0.8	0.333333333333333	0.5	2.56816439701713e-12	0.0832724893457054
114	WP4204	Tumor suppressor activity of SMARCB1	357	WP4204	33	0.79	0.269230769230769	0.423076923076923	7.79200875278231e-09	0.0908144088489654
115	WP4719	Eicosanoid metabolism via Cyclo Oxygenases (COX)	490	WP4719	30	0.7	0.333333333333333	0.380952380952381	2.17394413943821e-22	0.0918721376616465
116	WP3611	Photodynamic therapy-induced AP-1 survival signaling.	230	WP3611	51	0.9	0.304347826086957	0.456521739130435	1.55030261832076e-25	0.093911573076689
117	WP2011	SREBF and miR33 in cholesterol and lipid homeostasis	64	WP2011	19	0.84	0.3125	0.4375	2.9447393377517e-11	0.103949453944605
118	WP3892	Development of pulmonary dendritic cells and macrophage subsets	288	WP3892	13	0.77	0.2	0.7	7.70437079680464e-06	0.111367348220358
119	WP2431	Spinal Cord Injury	114	WP2431	120	0.75	0.322222222222222	0.4	5.53853655041636e-45	0.114048118916392
120	WP272	Blood Clotting Cascade	148	WP272	23	0.52	0.333333333333333	0.5	1.05891161032475e-42	0.114803285411883
121	WP117	GPCRs, Other	5	WP117	94	0.23	0.318181818181818	0.363636363636364	3.77273931182897e-18	0.120172770046016
122	WP3596	miR-517 relationship with ARCN1 and USP1	227	WP3596	5	1	0.2	0.4	7.70437079680464e-06	0.123137649892892
123	WP3672	LncRNA-mediated mechanisms of therapeutic resistance	257	WP3672	12	0.58	0.285714285714286	0.428571428571429	1.61117377276123e-06	0.123137649892892
124	WP3995	Prion disease pathway	324	WP3995	37	0.84	0.258064516129032	0.419354838709677	1.42295577093001e-17	0.148008766451471
125	WP4147	PTF1A related regulatory pathway	342	WP4147	11	0.45	0.2	0.4	0.000808563677475246	0.156029921726251
126	WP2849	Hematopoietic Stem Cell Differentiation	163	WP2849	63	0.68	0.325581395348837	0.395348837209302	1.4645909158934e-29	0.156167098725433
127	WP3958	GPR40 Pathway	313	WP3958	16	0.81	0.307692307692308	0.538461538461538	1.06179313771239e-06	0.156624702837221
128	WP4249	Hedgehog Signaling Pathway	376	WP4249	44	0.77	0.264705882352941	0.411764705882353	6.45939424963396e-09	0.171056939850016
129	WP2846	Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation	161	WP2846	3	0.33	0	1	0.191601747736878	0.191601747736878
130	WP3408	Evolocumab Mechanism	213	WP3408	3	0.33	0	1	0.191601747736878	0.191601747736878
131	WP2118	Arrhythmogenic Right Ventricular Cardiomyopathy	80	WP2118	76	0.74	0.303571428571429	0.410714285714286	6.58880500842654e-23	0.19520059624092
132	WP3640	Imatinib and Chronic Myeloid Leukemia	243	WP3640	21	0.95	0.3	0.4	3.36912948711107e-08	0.202640916207215
133	WP2007	Iron metabolism in placenta	63	WP2007	12	0.67	0.25	0.375	0.000425327317103322	0.20667484530917
134	WP129	Matrix Metalloproteinases	8	WP129	30	0.73	0.272727272727273	0.409090909090909	1.66846236358396e-28	0.217106999492912
135	WP4754	IL-18 signaling pathway	505	WP4754	279	0.8	0.265765765765766	0.373873873873874	5.53853655041636e-45	0.224063872360977
136	WP3301	MFAP5-mediated ovarian cancer cell motility and invasiveness	207	WP3301	13	1	0.230769230769231	0.384615384615385	7.1834548445351e-10	0.236415904297976
137	WP704	Methylation Pathways	555	WP704	10	0.7	0.142857142857143	0.428571428571429	1.10795143781028e-12	0.241165469354808
138	WP3930	EDA Signalling in Hair Follicle Development	297	WP3930	14	0.64	0.222222222222222	0.555555555555556	6.78928901696758e-07	0.24293224118149
139	WP3967	miR-509-3p alteration of YAP1/ECM axis	317	WP3967	19	0.89	0.235294117647059	0.352941176470588	3.92971708713555e-06	0.246081089028509
140	WP2858	Ectoderm Differentiation	168	WP2858	144	0.78	0.285714285714286	0.366071428571429	6.10911950894992e-26	0.251410075884791
141	WP428	Wnt Signaling	384	WP428	118	0.79	0.301075268817204	0.365591397849462	5.00019440781505e-25	0.251410075884791
142	WP1434	Osteopontin Signaling	19	WP1434	13	1	0.230769230769231	0.461538461538462	1.51229007711679e-12	0.257536764433672
143	WP176	Folate Metabolism	46	WP176	73	0.6	0.295454545454545	0.409090909090909	1.55030261832076e-25	0.257536764433672
144	WP28	Selenium Metabolism and Selenoproteins	150	WP28	46	0.61	0.25	0.392857142857143	2.4987918295779e-23	0.257536764433672
145	WP2840	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)	160	WP2840	88	0.64	0.267857142857143	0.375	1.4645909158934e-29	0.257536764433672
146	WP3617	Photodynamic therapy-induced NF-kB survival signaling	234	WP3617	35	0.86	0.233333333333333	0.4	1.55030261832076e-25	0.257536764433672
147	WP2059	Alzheimers Disease	75	WP2059	150	0.46	0.260869565217391	0.36231884057971	6.52294438984146e-17	0.264407820025205
148	WP4658	Small cell lung cancer	478	WP4658	98	0.91	0.269662921348315	0.359550561797753	1.33825325438479e-13	0.266714097046007
149	WP237	Glucocorticoid and Mineralcorticoid Metabolism	107	WP237	8	0.25	0	0.5	0.273007477872406	0.273007477872406
150	WP3287	Overview of nanoparticle effects	202	WP3287	19	0.79	0.266666666666667	0.4	1.55030261832076e-25	0.292450502904674
151	WP4586	Metabolism of alpha-linolenic acid	470	WP4586	7	0.86	0.166666666666667	0.5	0.0386740237126384	0.296626199889639
152	WP3580	Methionine De Novo and Salvage Pathway	220	WP3580	22	0.86	0.210526315789474	0.368421052631579	4.35964063989166e-11	0.301026666733762
153	WP4481	Resistin as a regulator of inflammation	422	WP4481	33	0.85	0.25	0.357142857142857	1.55030261832076e-25	0.310639518319511
154	WP3595	mir-124 predicted interactions with cell cycle and differentiation	226	WP3595	7	0.86	0.333333333333333	0.5	1.28871879017951e-06	0.311537001183337
155	WP4225	Pyrimidine metabolism and related diseases	369	WP4225	17	0.71	0.25	0.416666666666667	1.65319775729734e-07	0.312696646387934
156	WP24	Peptide GPCRs	111	WP24	75	0.28	0.285714285714286	0.428571428571429	1.91116166189054e-21	0.317365436064072
157	WP4336	ncRNAs involved in Wnt signaling in hepatocellular carcinoma	405	WP4336	91	0.76	0.289855072463768	0.36231884057971	5.00019440781505e-25	0.320170838547363
158	WP4462	Platelet-mediated interactions with vascular and circulating cells	418	WP4462	17	0.88	0.266666666666667	0.4	1.28837373141904e-08	0.341095356415239
159	WP4493	Cells and Molecules involved in local acute inflammatory response	426	WP4493	17	0.76	0.307692307692308	0.384615384615385	1.55030261832076e-25	0.341095356415239
160	WP3670	Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway	256	WP3670	21	0.81	0.176470588235294	0.352941176470588	2.45932835171728e-12	0.357129134137342
161	WP4538	Regulatory circuits of the STAT3 signaling pathway	447	WP4538	79	0.85	0.26865671641791	0.343283582089552	1.91116166189054e-21	0.363878327573958
162	WP229	Irinotecan Pathway	90	WP229	13	0.54	0.285714285714286	0.428571428571429	1.87627142351219e-05	0.372595026103777
163	WP4172	PI3K-Akt Signaling Pathway	350	WP4172	345	0.73	0.281746031746032	0.361111111111111	1.96319556679318e-26	0.389653492019368
164	WP3584	MECP2 and Associated Rett Syndrome	221	WP3584	71	0.72	0.274509803921569	0.352941176470588	2.08918249834541e-15	0.389709140526829
165	WP530	Cytokines and Inflammatory Response	524	WP530	27	0.52	0.214285714285714	0.357142857142857	1.55030261832076e-25	0.394616722859002
166	WP3888	VEGFA-VEGFR2 Signaling Pathway	286	WP3888	438	0.92	0.255583126550869	0.359801488833747	5.53853655041636e-45	0.415827475604265
167	WP4537	Hippo-Yap signaling pathway	446	WP4537	23	1	0.130434782608696	0.347826086956522	1.54778757247964e-06	0.425582638865984
168	WP4673	Genes involved in male infertility	483	WP4673	155	0.55	0.223529411764706	0.352941176470588	8.15687289296435e-21	0.434708802034794
169	WP4258	LncRNA involvement in canonical Wnt signaling and colorectal cancer	378	WP4258	104	0.73	0.276315789473684	0.342105263157895	5.00019440781505e-25	0.442641490692933
170	WP1528	Physiological and Pathological Hypertrophy of the Heart	26	WP1528	25	0.96	0.291666666666667	0.375	1.45750470372243e-17	0.443468145964458
171	WP1539	Angiogenesis	30	WP1539	24	1	0.25	0.375	2.08918249834541e-15	0.443468145964458
172	WP2586	Aryl Hydrocarbon Receptor Netpath	136	WP2586	48	0.83	0.225	0.35	1.44400359316927e-08	0.452666162731714
173	WP2865	IL1 and megakaryocytes in obesity	171	WP2865	25	0.84	0.238095238095238	0.380952380952381	5.19525794232389e-10	0.452666162731714
174	WP384	Apoptosis Modulation by HSP70	266	WP384	19	0.95	0.166666666666667	0.388888888888889	6.96540853859659e-18	0.452666162731714
175	WP706	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	556	WP706	164	0.61	0.31	0.35	7.75341732836066e-26	0.452666162731714
176	WP1742	TP53 Network	45	WP1742	20	0.9	0.222222222222222	0.388888888888889	1.28737203377495e-08	0.467750156194828
177	WP2507	Nanomaterial induced apoptosis	124	WP2507	20	0.95	0.105263157894737	0.368421052631579	1.28737203377495e-08	0.467750156194828
178	WP2267	Synaptic Vesicle Pathway	86	WP2267	52	0.6	0.258064516129032	0.354838709677419	6.97840140254166e-30	0.492132771972666
179	WP2038	Regulation of Microtubule Cytoskeleton	73	WP2038	49	0.86	0.285714285714286	0.357142857142857	5.70447887867626e-23	0.498108980109511
180	WP3594	Circadian rhythm related genes	225	WP3594	207	0.67	0.289855072463768	0.340579710144928	1.86144948015588e-42	0.502912219194388
181	WP186	Homologous recombination	51	WP186	13	0.92	0.333333333333333	0.333333333333333	3.57124737003596e-13	0.503680038828547
182	WP4299	Lamin A-processing pathway	392	WP4299	3	1	0.333333333333333	0.333333333333333	0.0375633720082355	0.525565992204199
183	WP26	Signal Transduction of S1P Receptor	139	WP26	26	0.92	0.208333333333333	0.333333333333333	1.36035451223937e-09	0.537154575485495
184	WP3932	Focal Adhesion-PI3K-Akt-mTOR-signaling pathway	299	WP3932	309	0.79	0.246913580246914	0.337448559670782	1.96319556679318e-26	0.55485006897197
185	WP3529	Zinc homeostasis	218	WP3529	37	0.65	0.208333333333333	0.333333333333333	1.09751947262418e-13	0.559735276252208
186	WP3613	Photodynamic therapy-induced unfolded protein response	232	WP3613	29	0.83	0.25	0.333333333333333	1.63572753987345e-09	0.592395677119481
187	WP455	GPCRs, Class A Rhodopsin-like	454	WP455	258	0.22	0.241379310344828	0.327586206896552	1.91116166189054e-21	0.594474156958518
188	WP314	Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation	198	WP314	44	0.91	0.175	0.325	1.28737203377495e-08	0.596740036001061
189	WP4321	Thermogenesis	401	WP4321	108	0.83	0.266666666666667	0.333333333333333	2.44977316588364e-24	0.602303776230422
190	WP1533	Vitamin B12 Metabolism	29	WP1533	53	0.57	0.2	0.333333333333333	1.55030261832076e-25	0.625924461178548
191	WP254	Apoptosis	132	WP254	86	0.93	0.225	0.3375	6.96540853859659e-18	0.630454225897172
192	WP2817	Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)	157	WP2817	33	0.76	0.32	0.32	8.1728342950092e-20	0.631033926043019
193	WP4286	Genotoxicity pathway	386	WP4286	63	0.78	0.244897959183673	0.326530612244898	6.52294438984146e-17	0.633739231633592
194	WP4228	Vitamin B6-dependent and responsive disorders	370	WP4228	5	0.8	0.25	0.25	0.00334024416831868	0.635216999029685
195	WP306	Focal Adhesion	195	WP306	202	0.86	0.248554913294798	0.323699421965318	1.96319556679318e-26	0.661870634611933
196	WP3941	Oxidative Damage	306	WP3941	41	0.9	0.243243243243243	0.324324324324324	1.28737203377495e-08	0.699923750757195
197	WP561	Heme Biosynthesis	533	WP561	9	0.89	0.25	0.25	6.5794345319789e-05	0.701076830955824
198	WP4541	Hippo-Merlin Signaling Dysregulation	450	WP4541	123	0.77	0.221052631578947	0.315789473684211	5.28168194977512e-22	0.723397294815617
199	WP2064	Neural Crest Differentiation	77	WP2064	102	0.63	0.25	0.328125	1.94200095136959e-19	0.727478052387628
200	WP3678	Amplification and Expansion of Oncogenic Pathways as Metastatic Traits	260	WP3678	17	1	0.117647058823529	0.294117647058824	6.04285700943382e-06	0.727478052387628
201	WP3935	Leptin Insulin Overlap	302	WP3935	17	0.82	0.285714285714286	0.285714285714286	9.45573250233619e-09	0.741018446305419
202	WP1772	Apoptosis Modulation and Signaling	47	WP1772	93	0.85	0.189873417721519	0.316455696202532	6.96540853859659e-18	0.744856843612274
203	WP2877	Vitamin D Receptor Pathway	178	WP2877	186	0.63	0.271186440677966	0.322033898305085	7.99040804992212e-20	0.818823949216948
204	WP1591	Heart Development	37	WP1591	46	0.65	0.266666666666667	0.3	1.16900918682e-14	0.842767793418932
205	WP4357	NRF2-ARE regulation	410	WP4357	23	0.96	0.227272727272727	0.318181818181818	6.33815645362995e-08	0.87065004588454
206	WP2882	Nuclear Receptors Meta-Pathway	183	WP2882	322	0.69	0.238738738738739	0.315315315315315	2.58938282317479e-38	0.88225486075262
207	WP2032	Human Thyroid Stimulating Hormone (TSH) signaling pathway	68	WP2032	68	0.91	0.274193548387097	0.32258064516129	8.47368187861688e-16	0.884931793800649
208	WP3998	Prader-Willi and Angelman Syndrome	326	WP3998	66	0.45	0.333333333333333	0.333333333333333	2.9765880724211e-12	0.892842095899067
209	WP2369	Histone Modifications	106	WP2369	70	0.43	0.166666666666667	0.3	4.29629046913145e-07	0.898693967045816
210	WP4540	Pathways Regulating Hippo Signaling	449	WP4540	99	0.81	0.225	0.325	1.45750470372243e-17	0.900720485325998
211	WP4022	Pyrimidine metabolism	331	WP4022	87	0.91	0.253164556962025	0.329113924050633	3.57124737003596e-13	0.90295173404126
212	WP4484	Control of immune tolerance by vasoactive intestinal peptide	425	WP4484	13	0.31	0	0.25	0.189083662421517	0.90837549057179
213	WP3527	Preimplantation Embryo	217	WP3527	60	0.52	0.193548387096774	0.290322580645161	1.4645909158934e-29	0.920619031124591
214	WP408	Oxidative Stress	335	WP408	34	0.85	0.206896551724138	0.310344827586207	2.4987918295779e-23	0.926181011736354
215	WP4297	Thiamine metabolic pathways	390	WP4297	9	0.89	0	0.25	0.171095325811961	0.927438681383965
216	WP1984	Integrated Breast Cancer Pathway	59	WP1984	155	0.92	0.27972027972028	0.314685314685315	3.61848623532521e-17	0.929014479457768
217	WP3972	PDGFR-beta pathway	320	WP3972	29	1	0.241379310344828	0.275862068965517	1.45750470372243e-17	0.936983896443534
218	WP15	Selenium Micronutrient Network	25	WP15	92	0.54	0.2	0.32	1.55030261832076e-25	0.94158668008034
219	WP1423	Ganglio Sphingolipid Metabolism	14	WP1423	13	0.62	0.25	0.25	4.87851969602103e-17	0.954898577153562
220	WP4298	Viral Acute Myocarditis	391	WP4298	85	0.82	0.228571428571429	0.314285714285714	1.55030261832076e-25	0.960973679911299
221	WP2374	Oncostatin M Signaling Pathway	109	WP2374	66	0.97	0.25	0.3125	1.45750470372243e-17	0.962619223865447
222	WP3850	Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling	270	WP3850	31	0.94	0.241379310344828	0.310344827586207	2.9447393377517e-11	0.979681670178472
223	WP3657	Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex	250	WP3657	22	0.86	0.315789473684211	0.315789473684211	1.28737203377495e-08	0.990973876560315
224	WP465	Tryptophan metabolism	474	WP465	42	0.64	0.259259259259259	0.333333333333333	1.2733947666864e-33	0.991085216247916
225	WP1541	Energy Metabolism	31	WP1541	48	0.88	0.30952380952381	0.333333333333333	4.7856489956754e-16	0.991457884585696
226	WP4148	Splicing factor NOVA regulated synaptic proteins	343	WP4148	42	0.74	0.258064516129032	0.32258064516129	8.59680057967434e-17	0.99308777325874
227	WP2380	Brain-Derived Neurotrophic Factor (BDNF) signaling pathway	110	WP2380	144	0.85	0.227642276422764	0.284552845528455	2.46076597989882e-17	0.993357395961217
228	WP183	Proteasome Degradation	49	WP183	64	0.91	0.189655172413793	0.258620689655172	0.000102727400071607	0.993739319892961
229	WP3942	PPAR signaling pathway	307	WP3942	67	0.67	0.244444444444444	0.266666666666667	4.45382103461115e-22	0.993946338790036
230	WP4341	Non-genomic actions of 1,25 dihydroxyvitamin D3	407	WP4341	71	0.82	0.224137931034483	0.310344827586207	1.55030261832076e-25	0.997223465039722
231	WP2036	TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway	71	WP2036	42	0.95	0.2	0.3	1.55030261832076e-25	0.998306181536745
232	WP262	EBV LMP1 signaling	140	WP262	24	0.83	0.2	0.3	1.31802719833037e-09	0.998306181536745
233	WP4008	NO/cGMP/PKG mediated Neuroprotection	328	WP4008	48	0.52	0.24	0.32	3.3920313877351e-19	0.998306181536745
234	WP4480	Role of Altered Glycolysation of MUC1 in Tumour Microenvironment	421	WP4480	9	0.89	0.125	0.25	1.55030261832076e-25	0.998306181536745
235	WP411	mRNA Processing	337	WP411	133	0.92	0.204918032786885	0.286885245901639	7.40715848733595e-20	0.999556795185293
236	WP4290	Metabolic reprogramming in colon cancer	388	WP4290	44	0.89	0.230769230769231	0.282051282051282	1.21134935033961e-14	0.999559974562214
237	WP2583	T-Cell Receptor and Co-stimulatory Signaling	135	WP2583	29	0.93	0.0740740740740741	0.185185185185185	0.0020390189701393	0.999564052655054
238	WP2113	Type III interferon signaling	79	WP2113	10	0.6	0.333333333333333	0.333333333333333	0.000341914298724229	0.999577405939352
239	WP2203	Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway	83	WP2203	47	0.96	0.2	0.266666666666667	1.55030261832076e-25	0.999581638329153
240	WP3929	Chemokine signaling pathway	296	WP3929	165	0.75	0.233870967741935	0.306451612903226	1.11151548949677e-22	0.999581638329153
241	WP2878	PPAR Alpha Pathway	179	WP2878	26	0.62	0.3125	0.3125	2.35000378034819e-10	0.999593630002801
242	WP4211	Transcriptional cascade regulating adipogenesis	361	WP4211	13	1	0.307692307692308	0.307692307692308	3.05550468161626e-32	0.999597380647255
243	WP395	IL-4 Signaling Pathway	312	WP395	55	0.96	0.169811320754717	0.264150943396226	1.21006371795151e-15	0.999598637344068
244	WP4756	Renin Angiotensin Aldosterone System (RAAS)	506	WP4756	44	0.64	0.214285714285714	0.285714285714286	3.79036700534385e-25	0.999600844420397
245	WP2037	Prolactin Signaling Pathway	72	WP2037	76	0.96	0.164383561643836	0.246575342465753	1.21006371795151e-15	0.999622158178795
246	WP3646	Hepatitis C and Hepatocellular Carcinoma	246	WP3646	50	0.88	0.25	0.340909090909091	1.55030261832076e-25	0.999661972130556
247	WP3414	Initiation of transcription and translation elongation at the HIV-1 LTR	215	WP3414	37	0.73	0.259259259259259	0.296296296296296	1.30274002920557e-12	0.999679395222021
248	WP1422	Sphingolipid pathway	13	WP1422	30	0.8	0.166666666666667	0.25	3.69949076638916e-07	0.999680873684117
249	WP4142	Metabolism of Spingolipids in ER and Golgi apparatus	340	WP4142	20	0.75	0.2	0.2	1.78651764239784e-05	0.999680873684117
250	WP4725	Sphingolipid Metabolism (general overview)	496	WP4725	24	0.83	0.2	0.25	1.3073328528498e-06	0.999680873684117
251	WP2359	Parkin-Ubiquitin Proteasomal System pathway	101	WP2359	70	0.84	0.152542372881356	0.23728813559322	1.33825325438479e-13	0.999692096078023
252	WP2911	miRNA targets in ECM and membrane receptors	188	WP2911	43	0.51	0.227272727272727	0.272727272727273	1.96319556679318e-26	0.999694369321929
253	WP4262	Breast cancer pathway	380	WP4262	157	0.77	0.214876033057851	0.28099173553719	8.1728342950092e-20	0.999736194038243
254	WP2636	Common Pathways Underlying Drug Addiction	141	WP2636	42	0.57	0.166666666666667	0.25	8.80436312071741e-23	0.999745706039956
255	WP2828	Bladder Cancer	159	WP2828	41	0.93	0.184210526315789	0.289473684210526	2.88662493064661e-07	0.999745706039956
256	WP3612	Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling	231	WP3612	24	0.88	0.0952380952380952	0.238095238095238	1.21006371795151e-15	0.999752419955776
257	WP4312	Rett syndrome causing genes	398	WP4312	49	0.76	0.216216216216216	0.297297297297297	1.22943627951508e-14	0.999766525303437
258	WP2533	Glycerophospholipid Biosynthetic Pathway	130	WP2533	30	0.83	0.08	0.16	3.98592395806362e-10	0.999787685558907
259	WP3940	One carbon metabolism and related pathways	305	WP3940	54	0.72	0.230769230769231	0.256410256410256	2.86780567028817e-25	0.999787685558907
260	WP4657	22q11.2 Deletion Syndrome	477	WP4657	92	0.63	0.258620689655172	0.310344827586207	5.10653311534479e-29	0.999801314777508
261	WP382	MAPK Signaling Pathway	264	WP382	249	0.78	0.261538461538462	0.302564102564103	5.53853655041636e-45	0.999829075430104
262	WP4666	Hepatitis B infection	482	WP4666	154	0.84	0.2	0.276923076923077	1.55030261832076e-25	0.999846173141814
263	WP107	Translation Factors	3	WP107	54	0.87	0.234042553191489	0.276595744680851	8.52450711689985e-13	0.999852323093054
264	WP1424	Globo Sphingolipid Metabolism	15	WP1424	21	0.95	0.2	0.2	4.87851969602103e-17	0.999852323093054
265	WP1584	Type II diabetes mellitus	35	WP1584	22	0.64	0.142857142857143	0.142857142857143	7.99040804992212e-20	0.999852323093054
266	WP2018	RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway	65	WP2018	55	0.95	0.0961538461538462	0.192307692307692	1.21006371795151e-15	0.999852323093054
267	WP231	TNF alpha Signaling Pathway	94	WP231	94	0.94	0.204545454545455	0.284090909090909	1.55030261832076e-25	0.999852323093054
268	WP2371	Parkinsons Disease Pathway	108	WP2371	84	0.37	0.193548387096774	0.290322580645161	6.96540853859659e-18	0.999852323093054
269	WP244	Alpha 6 Beta 4 signaling pathway	116	WP244	35	0.94	0.121212121212121	0.181818181818182	2.61142544133486e-11	0.999852323093054
270	WP2453	TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)	119	WP2453	16	0.94	0.0666666666666667	0.0666666666666667	1.10524321914212e-13	0.999852323093054
271	WP2456	HIF1A and PPARG regulation of glycolysis	120	WP2456	8	0.75	0.166666666666667	0.166666666666667	0.00320215171958638	0.999852323093054
272	WP2854	Gene regulatory network modelling somitogenesis	165	WP2854	11	0.55	0.166666666666667	0.166666666666667	0.0396104615656672	0.999852323093054
273	WP2870	Extracellular vesicle-mediated signaling in recipient cells	173	WP2870	30	0.9	0.185185185185185	0.222222222222222	1.47923810515956e-16	0.999852323093054
274	WP3	Phytochemical activity on NRF2 transcriptional activation	193	WP3	15	0.93	0.0714285714285714	0.214285714285714	0.00237947159212301	0.999852323093054
275	WP3286	Copper homeostasis	201	WP3286	54	0.87	0.234042553191489	0.297872340425532	3.71596808468601e-16	0.999852323093054
276	WP3298	Melatonin metabolism and effects	204	WP3298	42	0.62	0.269230769230769	0.307692307692308	1.86144948015588e-42	0.999852323093054
277	WP3413	NOTCH1 regulation of human endothelial cell calcification	214	WP3413	18	0.89	0.125	0.125	2.23804617426945e-12	0.999852323093054
278	WP3601	Composition of Lipid Particles	229	WP3601	10	0.4	0	0.25	0.191601747736878	0.999852323093054
279	WP3633	Caffeine and Theobromine metabolism	239	WP3633	4	0.25	0	0	0.999852323093054	0.999852323093054
280	WP3664	Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds	253	WP3664	18	0.89	0.1875	0.3125	8.33920870140507e-09	0.999852323093054
281	WP3845	Canonical and Non-canonical Notch signaling	268	WP3845	27	0.81	0.0909090909090909	0.181818181818182	0.000608063456248664	0.999852323093054
282	WP3859	TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition	274	WP3859	18	0.94	0.0588235294117647	0.0588235294117647	2.97846854097459e-06	0.999852323093054
283	WP3931	ESC Pluripotency Pathways	298	WP3931	119	0.7	0.265060240963855	0.289156626506024	1.04633266994318e-15	0.999852323093054
284	WP3945	TYROBP Causal Network	310	WP3945	63	0.9	0.12280701754386	0.175438596491228	1.51229007711679e-12	0.999852323093054
285	WP3965	Lipid Metabolism Pathway	316	WP3965	29	0.9	0.269230769230769	0.269230769230769	1.10524321914212e-13	0.999852323093054
286	WP3982	miRNA regulation of p53 pathway in prostate cancer	322	WP3982	34	0.68	0.0869565217391304	0.217391304347826	4.32292432502445e-07	0.999852323093054
287	WP4153	Degradation pathway of sphingolipids, including diseases	346	WP4153	10	0.8	0	0	0.999852323093054	0.999852323093054
288	WP4156	Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases	348	WP4156	2	1	0	0	0.999852323093054	0.999852323093054
289	WP4159	GABA receptor Signaling	349	WP4159	33	0.39	0.0769230769230769	0.0769230769230769	0.0013300266749614	0.999852323093054
290	WP4220	Neurotransmitter Disorders	365	WP4220	4	0.25	0	0	0.999852323093054	0.999852323093054
291	WP43	Oxidation by Cytochrome P450	393	WP43	63	0.48	0.133333333333333	0.166666666666667	7.53565262981462e-07	0.999852323093054
292	WP4320	The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome	400	WP4320	39	0.56	0.227272727272727	0.227272727272727	5.61788394294512e-16	0.999852323093054
293	WP4342	Vitamins A and D - action mechanisms	408	WP4342	3	1	0.333333333333333	0.333333333333333	1.20099662033474e-06	0.999852323093054
294	WP437	EGF/EGFR Signaling Pathway	411	WP437	164	0.95	0.206451612903226	0.232258064516129	1.4645909158934e-29	0.999852323093054
295	WP4482	Vitamin D in inflammatory diseases	423	WP4482	22	0.95	0.19047619047619	0.285714285714286	1.16949610776226e-27	0.999852323093054
296	WP4483	Relationship between inflammation, COX-2 and EGFR	424	WP4483	25	0.88	0.272727272727273	0.318181818181818	6.500496706318e-05	0.999852323093054
297	WP4519	Cerebral Organic Acidurias, including diseases	435	WP4519	7	1	0.285714285714286	0.285714285714286	1.97077141104003e-05	0.999852323093054
298	WP4522	Metabolic pathway of LDL, HDL and TG, including diseases	437	WP4522	17	0.53	0	0.222222222222222	0.0725218231021907	0.999852323093054
299	WP4535	Envelope proteins and their potential roles in EDMD physiopathology	444	WP4535	46	0.89	0.24390243902439	0.268292682926829	1.11151548949677e-22	0.999852323093054
300	WP4549	Fragile X Syndrome	453	WP4549	123	0.76	0.172043010752688	0.21505376344086	6.52294438984146e-17	0.999852323093054
301	WP4562	Canonical NF-KB pathway	460	WP4562	8	1	0	0.125	0.452666162731714	0.999852323093054
302	WP4585	Cancer immunotherapy by PD-1 blockade	469	WP4585	24	0.88	0.0952380952380952	0.19047619047619	2.79548473355309e-05	0.999852323093054
303	WP4724	Omega-9 FA synthesis	495	WP4724	16	0.75	0.166666666666667	0.25	9.83107916736652e-08	0.999852323093054
304	WP4758	Nephrotic syndrome	507	WP4758	45	0.73	0.151515151515152	0.181818181818182	7.19331431961561e-10	0.999852323093054
305	WP550	Biogenic Amine Synthesis	529	WP550	16	0.19	0.333333333333333	0.333333333333333	0.0013300266749614	0.999852323093054
306	WP100	Glutathione metabolism	1	WP100	23	0.7	0.0625	0.0625	2.4987918295779e-23	0.999852323093054
307	WP106	Alanine and aspartate metabolism	2	WP106	12	0.58	0.142857142857143	0.142857142857143	0.0013300266749614	0.999852323093054
308	WP111	Electron Transport Chain (OXPHOS system in mitochondria)	4	WP111	106	0.66	0.0714285714285714	0.128571428571429	1.43014316833318e-19	0.999852323093054
309	WP12	Osteoclast Signaling	6	WP12	16	0.75	0.166666666666667	0.25	1.51229007711679e-12	0.999852323093054
310	WP134	Pentose Phosphate Metabolism	9	WP134	7	1	0	0.142857142857143	0.154107526146787	0.999852323093054
311	WP1403	AMP-activated Protein Kinase (AMPK) Signaling	12	WP1403	69	0.81	0.178571428571429	0.25	7.99040804992212e-20	0.999852323093054
312	WP143	Fatty Acid Beta Oxidation	17	WP143	34	0.79	0.111111111111111	0.111111111111111	6.0888051023505e-05	0.999852323093054
313	WP1433	Nucleotide-binding Oligomerization Domain (NOD) pathway	18	WP1433	41	0.78	0.0625	0.125	4.08325260581342e-05	0.999852323093054
314	WP1449	Regulation of toll-like receptor signaling pathway	21	WP1449	145	0.77	0.117117117117117	0.198198198198198	1.55030261832076e-25	0.999852323093054
315	WP1471	Target Of Rapamycin (TOR) Signaling	23	WP1471	37	0.92	0.0882352941176471	0.117647058823529	8.28904921253337e-06	0.999852323093054
316	WP1531	Vitamin D Metabolism	28	WP1531	10	0.7	0.285714285714286	0.285714285714286	2.36116814219851e-05	0.999852323093054
317	WP1544	MicroRNAs in cardiomyocyte hypertrophy	32	WP1544	101	0.75	0.223684210526316	0.263157894736842	1.45750470372243e-17	0.999852323093054
318	WP1589	Folate-Alcohol and Cancer Pathway Hypotheses	36	WP1589	9	0.89	0.125	0.25	2.91348117795513e-05	0.999852323093054
319	WP185	Integrin-mediated Cell Adhesion	50	WP185	104	0.84	0.195402298850575	0.218390804597701	5.28168194977512e-22	0.999852323093054
320	WP1941	Peroxisomal beta-oxidation of tetracosanoyl-CoA	52	WP1941	4	1	0	0	0.999852323093054	0.999852323093054
321	WP195	IL-1 signaling pathway	54	WP195	57	0.96	0.127272727272727	0.181818181818182	1.5288509675647e-18	0.999852323093054
322	WP197	Cholesterol Biosynthesis Pathway	55	WP197	15	0.93	0.214285714285714	0.285714285714286	2.36116814219851e-05	0.999852323093054
323	WP1982	Sterol Regulatory Element-Binding Proteins (SREBP) signalling	58	WP1982	73	0.88	0.140625	0.171875	1.10524321914212e-13	0.999852323093054
324	WP2035	Follicle Stimulating Hormone (FSH) signaling pathway	70	WP2035	27	0.81	0.181818181818182	0.272727272727273	1.84528135455106e-08	0.999852323093054
325	WP205	IL-7 Signaling Pathway	74	WP205	25	1	0.16	0.2	0.000601597866207179	0.999852323093054
326	WP2112	IL17 signaling pathway	78	WP2112	32	0.84	0.148148148148148	0.222222222222222	1.31802719833037e-09	0.999852323093054
327	WP22	IL-9 Signaling Pathway	82	WP22	19	0.79	0.0666666666666667	0.0666666666666667	0.000601597866207179	0.999852323093054
328	WP2249	Metastatic brain tumor	84	WP2249	28	0.21	0.166666666666667	0.333333333333333	0.00291300857028192	0.999852323093054
329	WP2261	Signaling Pathways in Glioblastoma	85	WP2261	83	0.96	0.2375	0.25	1.45750470372243e-17	0.999852323093054
330	WP2272	Pathogenic Escherichia coli infection	87	WP2272	55	0.85	0.0851063829787234	0.191489361702128	4.18564642105688e-07	0.999852323093054
331	WP2289	Drug Induction of Bile Acid Pathway	89	WP2289	17	0.24	0.25	0.25	6.49286728094462e-06	0.999852323093054
332	WP2291	Deregulation of Rab and Rab Effector Genes in Bladder Cancer	92	WP2291	16	0.94	0.266666666666667	0.266666666666667	3.11005970071626e-15	0.999852323093054
333	WP2324	AGE/RAGE pathway	95	WP2324	66	0.95	0.142857142857143	0.206349206349206	1.45750470372243e-17	0.999852323093054
334	WP2333	Trans-sulfuration pathway	98	WP2333	10	1	0.2	0.2	7.49087453817701e-07	0.999852323093054
335	WP2436	Dopamine metabolism	115	WP2436	14	0.64	0.222222222222222	0.222222222222222	6.78665345557183e-11	0.999852323093054
336	WP2447	Amyotrophic lateral sclerosis (ALS)	118	WP2447	38	0.79	0.166666666666667	0.3	1.30274002920557e-12	0.999852323093054
337	WP2485	NAD Biosynthesis II (from tryptophan)	122	WP2485	8	0.75	0.166666666666667	0.166666666666667	1.2733947666864e-33	0.999852323093054
338	WP2509	Nanoparticle triggered autophagic cell death	125	WP2509	24	0.88	0.142857142857143	0.142857142857143	1.28737203377495e-08	0.999852323093054
339	WP2513	Nanoparticle triggered regulated necrosis	126	WP2513	12	0.92	0	0	0.795485118928105	0.999852323093054
340	WP2526	PDGF Pathway	129	WP2526	40	0.98	0.0769230769230769	0.128205128205128	1.21006371795151e-15	0.999852323093054
341	WP2572	Primary Focal Segmental Glomerulosclerosis FSGS	134	WP2572	74	0.78	0.275862068965517	0.310344827586207	4.81412003815079e-10	0.999852323093054
342	WP2637	Structural Pathway of Interleukin 1 (IL-1)	142	WP2637	50	0.98	0.142857142857143	0.204081632653061	1.21006371795151e-15	0.999852323093054
343	WP2643	Nanoparticle-mediated activation of receptor signaling	144	WP2643	29	0.97	0.178571428571429	0.214285714285714	0.00101315545629077	0.999852323093054
344	WP268	Notch Signaling	147	WP268	47	0.85	0.175	0.225	6.84417911248327e-08	0.999852323093054
345	WP2805	exRNA mechanism of action and biogenesis	151	WP2805	8	0.62	0.2	0.2	0.000217368536815086	0.999852323093054
346	WP2813	Mammary gland development pathway - Embryonic development (Stage 1 of 4)	153	WP2813	18	0.61	0.272727272727273	0.272727272727273	1.1219536394885e-16	0.999852323093054
347	WP2853	Endoderm Differentiation	164	WP2853	146	0.77	0.223214285714286	0.258928571428571	5.00019440781505e-25	0.999852323093054
348	WP2857	Mesodermal Commitment Pathway	167	WP2857	157	0.74	0.206896551724138	0.258620689655172	5.00019440781505e-25	0.999852323093054
349	WP286	IL-3 Signaling Pathway	169	WP286	49	0.9	0.159090909090909	0.204545454545455	1.21006371795151e-15	0.999852323093054
350	WP2864	Apoptosis-related network due to altered Notch3 in ovarian cancer	170	WP2864	54	0.93	0.16	0.28	4.12289297028431e-17	0.999852323093054
351	WP2868	TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer	172	WP2868	5	1	0	0	0.999852323093054	0.999852323093054
352	WP2873	Aryl Hydrocarbon Receptor Pathway	174	WP2873	48	0.65	0.129032258064516	0.225806451612903	4.12289297028431e-17	0.999852323093054
353	WP2875	Constitutive Androstane Receptor Pathway	176	WP2875	32	0.53	0.176470588235294	0.235294117647059	2.9447393377517e-11	0.999852323093054
354	WP2876	Pregnane X Receptor pathway	177	WP2876	33	0.55	0.166666666666667	0.222222222222222	2.9447393377517e-11	0.999852323093054
355	WP288	NLR Proteins	181	WP288	9	0.89	0.125	0.125	0.00237947159212301	0.999852323093054
356	WP2884	NRF2 pathway	184	WP2884	146	0.66	0.1875	0.260416666666667	2.4987918295779e-23	0.999852323093054
357	WP2889	Oxytocin signaling	185	WP2889	4	0.5	0	0	0.999852323093054	0.999852323093054
358	WP2916	Interactome of polycomb repressive complex 2 (PRC2)	189	WP2916	17	0.94	0.1875	0.3125	6.05665966147348e-07	0.999852323093054
359	WP2942	DDX1 as a regulatory component of the Drosha microprocessor	190	WP2942	9	0.67	0	0	0.990973876560315	0.999852323093054
360	WP299	Nuclear Receptors in Lipid Metabolism and Toxicity	192	WP299	35	0.46	0.25	0.25	1.20099662033474e-06	0.999852323093054
361	WP304	Kit receptor signaling pathway	194	WP304	60	0.98	0.169491525423729	0.220338983050847	1.45750470372243e-17	0.999852323093054
362	WP311	Synthesis and Degradation of Ketone Bodies	196	WP311	5	1	0.2	0.2	6.0888051023505e-05	0.999852323093054
363	WP313	Signaling of Hepatocyte Growth Factor Receptor	197	WP313	34	1	0.176470588235294	0.205882352941176	1.21006371795151e-15	0.999852323093054
364	WP325	Triacylglyceride Synthesis	200	WP325	26	0.54	0	0	0.999852323093054	0.999852323093054
365	WP3300	Dual hijack model of Vif in HIV infection	206	WP3300	9	0.67	0	0.166666666666667	0.118228105072828	0.999852323093054
366	WP3302	eIF5A regulation in response to inhibition of the nuclear export system	208	WP3302	4	0.75	0.333333333333333	0.333333333333333	0.00071352422837791	0.999852323093054
367	WP3303	RAC1/PAK1/p38/MMP2 Pathway	209	WP3303	69	0.9	0.225806451612903	0.274193548387097	3.11796204582401e-18	0.999852323093054
368	WP357	Fatty Acid Biosynthesis	219	WP357	22	0.91	0.2	0.2	1.10524321914212e-13	0.999852323093054
369	WP3593	MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma	224	WP3593	9	0.78	0	0	0.999852323093054	0.999852323093054
370	WP363	Wnt Signaling Pathway (Netpath)	237	WP363	53	0.91	0.208333333333333	0.208333333333333	1.45750470372243e-17	0.999852323093054
371	WP3630	NAD metabolism, sirtuins and aging	238	WP3630	11	0.91	0.2	0.3	2.25748011539398e-08	0.999852323093054
372	WP3634	Insulin signalling in human adipocytes (normal condition)	240	WP3634	8	1	0.125	0.125	7.99040804992212e-20	0.999852323093054
373	WP3635	Insulin signalling in human adipocytes (diabetic condition)	241	WP3635	8	1	0.125	0.125	7.99040804992212e-20	0.999852323093054
374	WP364	IL-6 signaling pathway	242	WP364	43	0.95	0.24390243902439	0.24390243902439	1.55030261832076e-25	0.999852323093054
375	WP3644	NAD+ metabolism	244	WP3644	16	0.88	0.142857142857143	0.285714285714286	2.25748011539398e-08	0.999852323093054
376	WP3645	NAD+ biosynthetic pathways	245	WP3645	22	0.77	0.176470588235294	0.294117647058824	2.25748011539398e-08	0.999852323093054
377	WP3651	Pathways Affected in Adenoid Cystic Carcinoma	247	WP3651	66	0.85	0.196428571428571	0.25	2.89465973850597e-12	0.999852323093054
378	WP3655	Hypothetical Craniofacial Development Pathway	248	WP3655	8	0.75	0.166666666666667	0.166666666666667	0.00407427421601939	0.999852323093054
379	WP3656	Interleukin-1 Induced Activation of NF-kappa-B	249	WP3656	11	0.91	0.1	0.2	0.00279989180752429	0.999852323093054
380	WP3658	Wnt/beta-catenin Signaling Pathway in Leukemia	251	WP3658	26	0.81	0.333333333333333	0.333333333333333	1.28160819617811e-23	0.999852323093054
381	WP366	TGF-beta Signaling Pathway	252	WP366	133	0.96	0.2109375	0.234375	1.4645909158934e-29	0.999852323093054
382	WP3668	Hypothesized Pathways in Pathogenesis of Cardiovascular Disease	255	WP3668	25	0.92	0.217391304347826	0.304347826086957	1.91116166189054e-21	0.999852323093054
383	WP3674	Tgif disruption of Shh signaling	258	WP3674	9	0.44	0	0	0.999852323093054	0.999852323093054
384	WP3676	BDNF-TrkB Signaling	259	WP3676	34	0.88	0.166666666666667	0.2	1.84528135455106e-08	0.999852323093054
385	WP368	Mitochondrial LC-Fatty Acid Beta-Oxidation	262	WP368	17	0.94	0.0625	0.0625	0.0167383786864681	0.999852323093054
386	WP3680	Association Between Physico-Chemical Features and Toxicity Associated Pathways	263	WP3680	68	0.81	0.163636363636364	0.2	1.46702371634426e-15	0.999852323093054
387	WP3844	PI3K-AKT-mTOR signaling pathway and therapeutic opportunities	267	WP3844	30	1	0.2	0.2	6.62772818839576e-10	0.999852323093054
388	WP3849	MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ	269	WP3849	12	1	0.166666666666667	0.25	1.31802719833037e-09	0.999852323093054
389	WP3851	TLR4 Signaling and Tolerance	271	WP3851	30	0.83	0.08	0.16	1.55030261832076e-25	0.999852323093054
390	WP3853	ERK Pathway in Huntington's Disease	272	WP3853	15	0.87	0.230769230769231	0.307692307692308	1.84528135455106e-08	0.999852323093054
391	WP3858	Toll-like Receptor Signaling related to MyD88	273	WP3858	32	0.84	0	0.111111111111111	0.114048118916392	0.999852323093054
392	WP3863	T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection	275	WP3863	62	0.81	0.14	0.22	1.21006371795151e-15	0.999852323093054
393	WP3865	Novel intracellular components of RIG-I-like receptor (RLR) pathway	276	WP3865	61	0.84	0.137254901960784	0.235294117647059	3.37870774082303e-13	0.999852323093054
394	WP3869	Cannabinoid receptor signaling	277	WP3869	29	0.79	0.0869565217391304	0.130434782608696	3.92161302035637e-08	0.999852323093054
395	WP3871	Valproic acid pathway	278	WP3871	13	0.62	0.125	0.125	0.0102047891408715	0.999852323093054
396	WP3874	Canonical and Non-Canonical TGF-B signaling	280	WP3874	17	1	0.0588235294117647	0.235294117647059	1.47923810515956e-16	0.999852323093054
397	WP3877	Simplified Depiction of MYD88 Distinct Input-Output Pathway	283	WP3877	19	0.74	0	0.214285714285714	0.0594386193019534	0.999852323093054
398	WP3878	ATM Signaling Network in Development and Disease	284	WP3878	46	0.89	0.219512195121951	0.268292682926829	2.50026382158374e-16	0.999852323093054
399	WP3879	4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression	285	WP3879	18	1	0.111111111111111	0.111111111111111	2.45237666239285e-07	0.999852323093054
400	WP391	Mitochondrial Gene Expression	290	WP391	20	0.8	0.125	0.1875	2.9447393377517e-11	0.999852323093054
401	WP3924	Hfe effect on hepcidin production	292	WP3924	7	0.57	0.25	0.25	0.00378182889135815	0.999852323093054
402	WP3925	Amino Acid metabolism	293	WP3925	91	0.73	0.166666666666667	0.227272727272727	2.58938282317479e-38	0.999852323093054
403	WP3927	BMP Signaling Pathway in Eyelid Development	295	WP3927	20	0.8	0.1875	0.25	1.1219536394885e-16	0.999852323093054
404	WP3933	Kennedy pathway from Sphingolipids	300	WP3933	15	0.8	0.0833333333333333	0.0833333333333333	0.000153115641692463	0.999852323093054
405	WP3934	Leptin and adiponectin	301	WP3934	10	0.8	0.125	0.125	1.13349503425421e-06	0.999852323093054
406	WP3937	Microglia Pathogen Phagocytosis Pathway	303	WP3937	40	0.9	0.0833333333333333	0.0833333333333333	1.57756315705304e-09	0.999852323093054
407	WP3938	miR-222 in Exercise-Induced Cardiac Growth	304	WP3938	4	1	0	0	0.999852323093054	0.999852323093054
408	WP3943	Robo4 and VEGF Signaling Pathways Crosstalk	308	WP3943	6	1	0.333333333333333	0.333333333333333	1.76304737966141e-10	0.999852323093054
409	WP3969	H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity	318	WP3969	16	0.88	0.214285714285714	0.214285714285714	7.1806031181162e-15	0.999852323093054
410	WP3971	Role of Osx and miRNAs in tooth development	319	WP3971	36	0.28	0.2	0.2	1.74501293167954e-14	0.999852323093054
411	WP3981	miRNA regulation of prostate cancer signaling pathways	321	WP3981	59	0.54	0.15625	0.21875	1.28737203377495e-08	0.999852323093054
412	WP399	Wnt Signaling Pathway and Pluripotency	323	WP399	107	0.8	0.232558139534884	0.290697674418605	1.45750470372243e-17	0.999852323093054
413	WP400	p38 MAPK Signaling Pathway	327	WP400	34	0.97	0.181818181818182	0.242424242424242	4.7856489956754e-16	0.999852323093054
414	WP4018	Pathways in clear cell renal cell carcinoma	330	WP4018	87	0.91	0.164556962025316	0.189873417721519	1.10524321914212e-13	0.999852323093054
415	WP405	Eukaryotic Transcription Initiation	334	WP405	43	0.95	0.0975609756097561	0.146341463414634	2.41984712730741e-07	0.999852323093054
416	WP410	Exercise-induced Circadian Regulation	336	WP410	49	0.9	0.272727272727273	0.295454545454545	1.86144948015588e-42	0.999852323093054
417	WP4136	Fibrin Complement Receptor 3 Signaling Pathway	338	WP4136	42	0.71	0.0666666666666667	0.166666666666667	1.55030261832076e-25	0.999852323093054
418	WP4141	PI3K/AKT/mTOR - VitD3 Signalling	339	WP4141	22	0.86	0.263157894736842	0.263157894736842	3.87043570690072e-12	0.999852323093054
419	WP4146	Macrophage markers	341	WP4146	9	1	0	0.111111111111111	0.21102640351702	0.999852323093054
420	WP4150	Wnt Signaling in Kidney Disease	345	WP4150	39	0.69	0.222222222222222	0.222222222222222	8.33920870140507e-09	0.999852323093054
421	WP4155	Endometrial cancer	347	WP4155	63	0.94	0.152542372881356	0.220338983050847	1.04633266994318e-15	0.999852323093054
422	WP4186	Somatroph axis (GH) and its relationship to dietary restriction and aging	352	WP4186	6	1	0.333333333333333	0.333333333333333	2.25748011539398e-08	0.999852323093054
423	WP4189	Mevalonate arm of cholesterol biosynthesis pathway with inhibitors	353	WP4189	2	1	0	0	0.999852323093054	0.999852323093054
424	WP4197	The human immune response to tuberculosis	356	WP4197	23	1	0.130434782608696	0.130434782608696	0.000341914298724229	0.999852323093054
425	WP4205	MET in type 1 papillary renal cell carcinoma	358	WP4205	59	0.88	0.115384615384615	0.173076923076923	3.90142119029615e-06	0.999852323093054
426	WP4206	Hereditary leiomyomatosis and renal cell carcinoma pathway	359	WP4206	20	0.95	0.105263157894737	0.210526315789474	2.03101031117154e-10	0.999852323093054
427	WP4210	Tryptophan catabolism leading to NAD+ production	360	WP4210	16	0.69	0.0909090909090909	0.0909090909090909	1.2733947666864e-33	0.999852323093054
428	WP4217	Ebola Virus Pathway on Host	363	WP4217	132	0.89	0.135593220338983	0.186440677966102	7.15702783093164e-17	0.999852323093054
429	WP422	MAPK Cascade	364	WP422	33	1	0.212121212121212	0.272727272727273	1.06179313771239e-06	0.999852323093054
430	WP4223	Ras Signaling	367	WP4223	186	0.76	0.204225352112676	0.26056338028169	2.6982385516733e-21	0.999852323093054
431	WP4236	Disorders of the Krebs cycle	372	WP4236	7	1	0.142857142857143	0.142857142857143	0.000542153786249434	0.999852323093054
432	WP4239	Epithelial to mesenchymal transition in colorectal cancer	373	WP4239	164	0.78	0.1953125	0.2578125	5.10653311534479e-29	0.999852323093054
433	WP4241	Type 2 papillary renal cell carcinoma	375	WP4241	36	0.83	0.133333333333333	0.166666666666667	6.62772818839576e-10	0.999852323093054
434	WP4255	Non-small cell lung cancer	377	WP4255	72	0.93	0.149253731343284	0.238805970149254	1.45750470372243e-17	0.999852323093054
435	WP4263	Pancreatic adenocarcinoma pathway	381	WP4263	89	0.96	0.141176470588235	0.211764705882353	1.47923810515956e-16	0.999852323093054
436	WP4271	Vitamin B12 Disorders	383	WP4271	13	0.69	0	0.222222222222222	0.105553301023444	0.999852323093054
437	WP4292	Methionine metabolism leading to Sulphur Amino Acids and related disorders	389	WP4292	11	0.82	0.222222222222222	0.222222222222222	5.6500805039415e-14	0.999852323093054
438	WP430	Statin Pathway	394	WP430	33	0.45	0.133333333333333	0.266666666666667	0.00133659811986492	0.999852323093054
439	WP4313	Ferroptosis	399	WP4313	40	0.9	0.138888888888889	0.194444444444444	1.14291084616521e-05	0.999852323093054
440	WP4331	Neovascularisation processes	404	WP4331	37	1	0.189189189189189	0.27027027027027	3.37870774082303e-13	0.999852323093054
441	WP4352	Ciliary landscape	409	WP4352	220	0.9	0.137055837563452	0.208121827411168	4.19419091059679e-15	0.999852323093054
442	WP4389	Bile Acids synthesis and enterohepatic circulation	413	WP4389	13	0.38	0	0.2	0.191601747736878	0.999852323093054
443	WP4396	Nonalcoholic fatty liver disease	414	WP4396	160	0.84	0.133333333333333	0.207407407407407	1.55030261832076e-25	0.999852323093054
444	WP4397	Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors	415	WP4397	3	0.67	0	0	0.999852323093054	0.999852323093054
445	WP4478	LTF danger signal response pathway	419	WP4478	20	0.7	0.0714285714285714	0.214285714285714	1.55030261832076e-25	0.999852323093054
446	WP4479	Supression of HMGB1 mediated inflammation by THBD	420	WP4479	9	1	0	0.111111111111111	0.452666162731714	0.999852323093054
447	WP4494	Selective expression of chemokine receptors during T-cell polarization	427	WP4494	29	0.55	0.0625	0.125	0.00407427421601939	0.999852323093054
448	WP4496	Signal transduction through IL1R	429	WP4496	35	0.86	0.133333333333333	0.233333333333333	1.55030261832076e-25	0.999852323093054
449	WP4504	Cysteine and methionine catabolism	431	WP4504	15	0.87	0.153846153846154	0.153846153846154	5.6500805039415e-14	0.999852323093054
450	WP4506	Tyrosine Metabolism	432	WP4506	4	0.25	0	0	0.999852323093054	0.999852323093054
451	WP4518	Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases	434	WP4518	10	0.5	0.2	0.2	0.000377573164229441	0.999852323093054
452	WP4521	Glycosylation and related congenital defects	436	WP4521	25	1	0.12	0.16	1.02496252421453e-08	0.999852323093054
453	WP4523	Classical pathway of steroidogenesis, including diseases	438	WP4523	16	0.31	0	0.2	0.273007477872406	0.999852323093054
454	WP4524	The alternative pathway of fetal androgen synthesis	439	WP4524	12	0.33	0.25	0.25	2.8033361067803e-09	0.999852323093054
455	WP453	Inflammatory Response Pathway	440	WP453	33	0.67	0.0909090909090909	0.181818181818182	0.000442098767154395	0.999852323093054
456	WP4532	Intraflagellar transport proteins binding to dynein	441	WP4532	27	0.93	0.08	0.16	0.00558066527342552	0.999852323093054
457	WP4533	Transcription co-factors SKI and SKIL protein partners	442	WP4533	18	1	0.166666666666667	0.277777777777778	1.54778757247964e-06	0.999852323093054
458	WP4536	Genes related to primary cilium development (based on CRISPR)	445	WP4536	103	0.92	0.105263157894737	0.189473684210526	8.57900007846234e-13	0.999852323093054
459	WP4539	Synaptic signaling pathways associated with autism spectrum disorder	448	WP4539	51	0.76	0.256410256410256	0.256410256410256	9.26038985479124e-09	0.999852323093054
460	WP4542	Overview of leukocyte-intrinsic Hippo pathway functions	451	WP4542	36	0.86	0.161290322580645	0.258064516129032	1.54778757247964e-06	0.999852323093054
461	WP4553	FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma	455	WP4553	38	0.29	0.181818181818182	0.272727272727273	3.04356671038824e-07	0.999852323093054
462	WP4559	Interactions between immune cells and microRNAs in tumor microenvironment	457	WP4559	40	0.6	0.125	0.25	1.47923810515956e-16	0.999852323093054
463	WP4561	Cell migration and invasion through p75NTR	459	WP4561	31	0.9	0.214285714285714	0.285714285714286	3.88351886854851e-13	0.999852323093054
464	WP4564	Neural Crest Cell Migration during Development	461	WP4564	41	0.8	0.151515151515152	0.242424242424242	1.21006371795151e-15	0.999852323093054
465	WP4565	Neural Crest Cell Migration in Cancer	462	WP4565	44	0.82	0.166666666666667	0.25	1.21006371795151e-15	0.999852323093054
466	WP4577	Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway	465	WP4577	44	0.98	0.0930232558139535	0.116279069767442	0.000303680199088757	0.999852323093054
467	WP4595	Urea cycle and associated pathways	472	WP4595	21	0.76	0.25	0.3125	1.21134935033961e-14	0.999852323093054
468	WP4629	Computational Model of Aerobic Glycolysis	473	WP4629	12	0.92	0.181818181818182	0.181818181818182	1.94971495989183e-05	0.999852323093054
469	WP4655	Cytosolic DNA-sensing pathway	475	WP4655	76	0.72	0.109090909090909	0.145454545454545	1.55030261832076e-25	0.999852323093054
470	WP4659	Gastrin Signaling Pathway	479	WP4659	114	0.92	0.180952380952381	0.238095238095238	4.7856489956754e-16	0.999852323093054
471	WP4674	Head and Neck Squamous Cell Carcinoma	484	WP4674	70	0.94	0.121212121212121	0.166666666666667	1.47923810515956e-16	0.999852323093054
472	WP4685	Melanoma	485	WP4685	68	0.93	0.174603174603175	0.26984126984127	1.21006371795151e-15	0.999852323093054
473	WP47	Hedgehog Signaling Pathway Netpath	487	WP47	16	0.75	0.0833333333333333	0.25	0.0317273821116764	0.999852323093054
474	WP4705	Pathways of nucleic acid metabolism and innate immune sensing	488	WP4705	16	0.81	0.153846153846154	0.153846153846154	1.16208386478435e-12	0.999852323093054
475	WP4718	Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)	489	WP4718	47	0.87	0.219512195121951	0.268292682926829	1.16398114740138e-08	0.999852323093054
476	WP4721	Eicosanoid metabolism via Lipo Oxygenases (LOX)	492	WP4721	29	0.69	0.2	0.25	4.45382103461115e-22	0.999852323093054
477	WP4722	Glycerolipids and Glycerophospholipids	493	WP4722	24	0.75	0.0555555555555556	0.0555555555555556	0.000153115641692463	0.999852323093054
478	WP4723	Omega-3/Omega-6 FA synthesis	494	WP4723	15	0.73	0	0.0909090909090909	0.296626199889639	0.999852323093054
479	WP4726	Sphingolipid Metabolism (integrated pathway)	497	WP4726	25	0.84	0.19047619047619	0.238095238095238	1.3073328528498e-06	0.999852323093054
480	WP4742	Ketogenesis and Ketolysis	499	WP4742	8	1	0.125	0.125	6.0888051023505e-05	0.999852323093054
481	WP4746	Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism	500	WP4746	95	0.69	0.227272727272727	0.272727272727273	2.44977316588364e-24	0.999852323093054
482	WP4747	Netrin-UNC5B signaling Pathway	501	WP4747	52	0.85	0.181818181818182	0.272727272727273	2.5665992363522e-08	0.999852323093054
483	WP4751	HIPK2 in kidney fibrosis	502	WP4751	2	1	0	0	0.999852323093054	0.999852323093054
484	WP4753	Nucleotide Excision Repair	504	WP4753	44	0.98	0.255813953488372	0.27906976744186	3.57124737003596e-13	0.999852323093054
485	WP4767	FGFR3 signalling in chondrocyte proliferation and terminal differentiation	509	WP4767	27	0.89	0.166666666666667	0.25	1.60955895014834e-18	0.999852323093054
486	WP477	Cytoplasmic Ribosomal Proteins	510	WP477	91	0.93	0.129411764705882	0.164705882352941	8.56966962716958e-10	0.999852323093054
487	WP4792	Purine metabolism	511	WP4792	13	0.85	0.272727272727273	0.272727272727273	3.92279863878209e-05	0.999852323093054
488	WP481	Insulin Signaling	512	WP481	161	0.93	0.186666666666667	0.246666666666667	2.30627807010563e-26	0.999852323093054
489	WP49	IL-2 Signaling Pathway	513	WP49	42	0.98	0.195121951219512	0.24390243902439	1.21006371795151e-15	0.999852323093054
490	WP496	Steroid Biosynthesis	514	WP496	10	0.4	0	0.25	0.386085732506969	0.999852323093054
491	WP500	Glycogen Synthesis and Degradation	516	WP500	40	0.9	0.138888888888889	0.194444444444444	9.51262628208688e-25	0.999852323093054
492	WP51	Regulation of Actin Cytoskeleton	518	WP51	151	0.77	0.213675213675214	0.273504273504274	1.04633266994318e-15	0.999852323093054
493	WP521	Amino acid conjugation of benzoic acid	520	WP521	5	0.2	0	0	0.999852323093054	0.999852323093054
494	WP524	G13 Signaling Pathway	521	WP524	41	0.85	0.2	0.2	6.63243812483213e-11	0.999852323093054
495	WP528	Acetylcholine Synthesis	522	WP528	7	0.57	0	0	0.999852323093054	0.999852323093054
496	WP534	Glycolysis and Gluconeogenesis	526	WP534	45	0.73	0.121212121212121	0.121212121212121	7.99040804992212e-20	0.999852323093054
497	WP560	TGF-beta Receptor Signaling	532	WP560	58	0.79	0.217391304347826	0.260869565217391	1.47923810515956e-16	0.999852323093054
498	WP581	EPO Receptor Signaling	535	WP581	26	0.96	0.08	0.08	0.000601597866207179	0.999852323093054
499	WP585	Interferon type I signaling pathways	536	WP585	55	0.95	0.173076923076923	0.230769230769231	9.45573250233619e-09	0.999852323093054
500	WP61	Notch Signaling Pathway Netpath	537	WP61	63	0.9	0.157894736842105	0.280701754385965	4.8712821556021e-23	0.999852323093054
501	WP615	Senescence and Autophagy in Cancer	538	WP615	108	0.86	0.193548387096774	0.258064516129032	1.55030261832076e-25	0.999852323093054
502	WP623	Oxidative phosphorylation	540	WP623	62	0.6	0	0.0540540540540541	0.0626324188453113	0.999852323093054
503	WP673	ErbB Signaling Pathway	542	WP673	91	0.89	0.209876543209877	0.259259259259259	3.46021469111041e-20	0.999852323093054
504	WP678	Arachidonate Epoxygenase / Epoxide Hydrolase	543	WP678	7	0.71	0.2	0.2	4.43345799464762e-09	0.999852323093054
505	WP688	Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)	544	WP688	5	0.6	0	0	0.999852323093054	0.999852323093054
506	WP690	Polyol Pathway	546	WP690	4	0.75	0	0	0.855645046418417	0.999852323093054
507	WP692	Sulfation Biotransformation Reaction	548	WP692	19	0.32	0	0	0.999852323093054	0.999852323093054
508	WP694	Arylamine metabolism	549	WP694	6	0.33	0	0	0.999852323093054	0.999852323093054
509	WP696	Benzo(a)pyrene metabolism	550	WP696	9	0.78	0	0.142857142857143	0.186101834726753	0.999852323093054
510	WP697	Estrogen metabolism	551	WP697	19	0.47	0	0	0.999852323093054	0.999852323093054
511	WP698	Glucuronidation	552	WP698	26	0.35	0.222222222222222	0.222222222222222	2.6913627863713e-23	0.999852323093054
512	WP699	Aflatoxin B1 metabolism	553	WP699	7	0.43	0	0	0.999852323093054	0.999852323093054
513	WP702	Metapathway biotransformation Phase I and II	554	WP702	188	0.48	0.133333333333333	0.188888888888889	2.4987918295779e-23	0.999852323093054
514	WP710	DNA Damage Response (only ATM dependent)	558	WP710	115	0.87	0.13	0.21	1.57756315705304e-09	0.999852323093054
515	WP712	Estrogen signaling pathway	559	WP712	23	0.91	0.19047619047619	0.333333333333333	1.21006371795151e-15	0.999852323093054
516	WP716	Vitamin A and Carotenoid Metabolism	560	WP716	44	0.5	0.181818181818182	0.272727272727273	9.28054409606823e-14	0.999852323093054
517	WP733	Serotonin Receptor 2 and STAT3 Signaling	563	WP733	4	0.75	0.333333333333333	0.333333333333333	0.0212542319346549	0.999852323093054
518	WP75	Toll-like Receptor Signaling Pathway	565	WP75	104	0.75	0.0897435897435897	0.179487179487179	1.55030261832076e-25	0.999852323093054
519	WP78	TCA Cycle (aka Krebs or citric acid cycle)	566	WP78	18	1	0	0.0555555555555556	0.345480440691871	0.999852323093054
520	WP80	Nucleotide GPCRs	567	WP80	11	0.73	0	0	0.999852323093054	0.999852323093054
521	WP127	IL-5 Signaling Pathway	7	WP127	40	0.95	0.236842105263158	0.263157894736842	1.21006371795151e-15	0.999852323093054
522	WP138	Androgen receptor signaling pathway	11	WP138	91	0.9	0.195121951219512	0.25609756097561	1.33825325438479e-13	0.999852323093054
523	WP1425	Bone Morphogenic Protein (BMP) Signalling and Regulation	16	WP1425	12	0.83	0.1	0.2	0.0044135122745415	0.999852323093054
524	WP1559	TFs Regulate miRNAs related to cardiac hypertrophy	34	WP1559	12	0.58	0	0.142857142857143	0.452666162731714	0.999852323093054
525	WP1946	Cori Cycle	53	WP1946	17	0.82	0.142857142857143	0.142857142857143	7.99040804992212e-20	0.999852323093054
526	WP2034	Leptin signaling pathway	69	WP2034	76	0.99	0.213333333333333	0.266666666666667	6.63243812483213e-11	0.999852323093054
527	WP2290	RalA downstream regulated genes	91	WP2290	12	0.92	0.181818181818182	0.181818181818182	1.57756315705304e-09	0.999852323093054
528	WP23	B Cell Receptor Signaling Pathway	93	WP23	98	0.94	0.184782608695652	0.260869565217391	1.45750470372243e-17	0.999852323093054
529	WP2328	Allograft Rejection	96	WP2328	90	0.69	0.17741935483871	0.209677419354839	2.86780567028817e-25	0.999852323093054
530	WP2332	Interleukin-11 Signaling Pathway	97	WP2332	44	0.91	0.225	0.25	3.51846221320189e-12	0.999852323093054
531	WP2795	Cardiac Hypertrophic Response	149	WP2795	57	0.89	0.196078431372549	0.254901960784314	2.08918249834541e-15	0.999852323093054
532	WP3614	Photodynamic therapy-induced HIF-1 survival signaling	233	WP3614	37	0.89	0.181818181818182	0.242424242424242	3.51846221320189e-12	0.999852323093054
533	WP3891	Benzene metabolism	287	WP3891	6	0.5	0	0	0.999852323093054	0.999852323093054
534	WP3915	Angiopoietin Like Protein 8 Regulatory Pathway	291	WP3915	132	0.89	0.136752136752137	0.170940170940171	7.99040804992212e-20	0.999852323093054
535	WP3926	ApoE and miR-146 in inflammation and atherosclerosis	294	WP3926	9	0.89	0	0.125	0.114048118916392	0.999852323093054
536	WP404	Nucleotide Metabolism	333	WP404	19	0.95	0.166666666666667	0.166666666666667	3.57124737003596e-13	0.999852323093054
537	WP4216	Chromosomal and microsatellite instability in colorectal cancer	362	WP4216	74	0.96	0.211267605633803	0.267605633802817	1.47923810515956e-16	0.999852323093054
538	WP4269	Ethanol metabolism resulting in production of ROS by CYP2E1	382	WP4269	10	0.9	0.111111111111111	0.333333333333333	7.45368111307164e-07	0.999852323093054
539	WP4288	MTHFR deficiency	387	WP4288	27	0.7	0.315789473684211	0.315789473684211	1.69249742410717e-08	0.999852323093054
540	WP4301	Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells	396	WP4301	18	1	0.166666666666667	0.222222222222222	9.01134422889796e-05	0.999852323093054
541	WP4324	Mitochondrial complex I assembly model OXPHOS system	402	WP4324	56	0.8	0	0.0222222222222222	0.0626324188453113	0.999852323093054
542	WP4329	miRNAs involvement in the immune response in sepsis	403	WP4329	64	0.5	0.0625	0.1875	1.55030261832076e-25	0.999852323093054
543	WP438	Non-homologous end joining	412	WP438	11	0.91	0.1	0.1	0.00934439177317729	0.999852323093054
544	WP4495	IL-10 Anti-inflammatory Signaling Pathway	428	WP4495	12	0.92	0.181818181818182	0.272727272727273	1.55030261832076e-25	0.999852323093054
545	WP4507	Molybdenum cofactor (Moco) biosynthesis	433	WP4507	7	1	0.142857142857143	0.285714285714286	3.39506009152496e-24	0.999852323093054
546	WP4534	Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms	443	WP4534	48	0.92	0.159090909090909	0.272727272727273	8.80436312071741e-23	0.999852323093054
547	WP4558	Overview of interferons-mediated signaling pathway	456	WP4558	37	0.38	0.214285714285714	0.214285714285714	0.000341914298724229	0.999852323093054
548	WP4566	Translation inhibitors in chronically activated PDGFRA cells	463	WP4566	48	0.94	0.177777777777778	0.2	8.56966962716958e-10	0.999852323093054
549	WP4582	Cancer immunotherapy by CTLA4 blockade	466	WP4582	15	0.8	0	0	0.835939678356078	0.999852323093054
550	WP4656	Joubert Syndrome	476	WP4656	77	0.9	0.130434782608696	0.217391304347826	4.67701164770016e-10	0.999852323093054
551	WP501	GPCRs, Class C Metabotropic glutamate, pheromone	517	WP501	16	0.31	0	0	0.999852323093054	0.999852323093054
552	WP619	Type II interferon signaling (IFNG)	539	WP619	37	0.84	0.193548387096774	0.258064516129032	9.44618578094348e-09	0.999852323093054
553	WP69	T-Cell antigen Receptor (TCR) Signaling Pathway	545	WP69	91	0.9	0.0975609756097561	0.182926829268293	1.55030261832076e-25	0.999852323093054
554	WP691	Tamoxifen metabolism	547	WP691	21	0.24	0.2	0.2	0.0372370714105519	0.999852323093054
555	WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling	562	WP732	20	0.75	0.2	0.266666666666667	6.52294438984146e-17	0.999852323093054
556	WP1981	Thyroxine (Thyroid Hormone) Production	57	WP1981	6	0	NA	NA	NA	NA
557	WP2491	Diclofenac Metabolic Pathway	123	WP2491	4	0	NA	NA	NA	NA
558	WP2536	Colchicine Metabolic Pathway	131	WP2536	1	0	NA	NA	NA	NA
559	WP2596	Gastric acid production	137	WP2596	7	0	NA	NA	NA	NA
560	WP2597	Secretion of Hydrochloric Acid in Parietal Cells	138	WP2597	5	0	NA	NA	NA	NA
561	WP2640	Aripiprazole Metabolic Pathway	143	WP2640	2	0	NA	NA	NA	NA
562	WP2646	Lidocaine metabolism	146	WP2646	2	0	NA	NA	NA	NA
563	WP2816	Felbamate Metabolism	156	WP2816	2	0	NA	NA	NA	NA
564	WP3627	Gut-Liver Indole Metabolism	236	WP3627	1	0	NA	NA	NA	NA
565	WP3666	Metabolism of Dichloroethylene by CYP450	254	WP3666	1	0	NA	NA	NA	NA
566	WP4174	Metabolism of Tetrahydrocannabinol (THC)	351	WP4174	2	0	NA	NA	NA	NA
567	WP4194	Hormonal control of Pubertal Growth Spurt	355	WP4194	2	0	NA	NA	NA	NA
568	WP4233	Acrylamide Biotransformation and Exposure Biomarkers	371	WP4233	1	0	NA	NA	NA	NA
569	WP661	Glucose Homeostasis	541	WP661	1	0	NA	NA	NA	NA